MX2022014736A - Anticuerpos anti-cd200r1 y metodos de uso de estos. - Google Patents
Anticuerpos anti-cd200r1 y metodos de uso de estos.Info
- Publication number
- MX2022014736A MX2022014736A MX2022014736A MX2022014736A MX2022014736A MX 2022014736 A MX2022014736 A MX 2022014736A MX 2022014736 A MX2022014736 A MX 2022014736A MX 2022014736 A MX2022014736 A MX 2022014736A MX 2022014736 A MX2022014736 A MX 2022014736A
- Authority
- MX
- Mexico
- Prior art keywords
- cd200r1
- antibodies
- inhibiting
- decreasing
- present disclosure
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 101000969553 Homo sapiens Cell surface glycoprotein CD200 receptor 1 Proteins 0.000 abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 102100021396 Cell surface glycoprotein CD200 receptor 1 Human genes 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 102000057542 human CD200R1 Human genes 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000009711 regulatory function Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Abstract
La presente divulgación proporciona proteínas de fijación, tales como anticuerpos y fragmentos de fijación al antígeno, que se fijan específicamente a la proteína receptora CD200R1 humana (hu-CD200R1) y que son capaces de disminuir, inhibir y/o bloquear por completo los efectos inmunorreguladores mediados por hu-CD200R1. La presente divulgación también proporciona métodos para usar los anticuerpos (y composiciones de estos) para tratar enfermedades y afecciones que responden a la disminución, inhibición y/o bloqueo de la función o actividad inmunorreguladora mediada por la fijación de CD200 a CD200R1.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063032508P | 2020-05-29 | 2020-05-29 | |
PCT/US2021/034852 WO2021243204A1 (en) | 2020-05-29 | 2021-05-28 | Anti-cd200r1 antibodies and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022014736A true MX2022014736A (es) | 2023-03-23 |
Family
ID=76624182
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022014736A MX2022014736A (es) | 2020-05-29 | 2021-05-28 | Anticuerpos anti-cd200r1 y metodos de uso de estos. |
Country Status (17)
Country | Link |
---|---|
US (2) | US11787861B2 (es) |
EP (1) | EP4157461A1 (es) |
JP (1) | JP2023528375A (es) |
KR (1) | KR20230018425A (es) |
CN (1) | CN116323665A (es) |
AR (1) | AR122213A1 (es) |
AU (1) | AU2021281417A1 (es) |
BR (1) | BR112022024339A2 (es) |
CA (1) | CA3178417A1 (es) |
CL (1) | CL2022003296A1 (es) |
CO (1) | CO2022016860A2 (es) |
CR (1) | CR20220608A (es) |
IL (1) | IL298668A (es) |
MX (1) | MX2022014736A (es) |
PE (1) | PE20230460A1 (es) |
TW (1) | TW202210512A (es) |
WO (1) | WO2021243204A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW202400651A (zh) * | 2022-05-19 | 2024-01-01 | 中國商和鉑醫藥(上海)有限責任公司 | 抗cd200r1抗體 |
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-
2021
- 2021-05-28 AU AU2021281417A patent/AU2021281417A1/en active Pending
- 2021-05-28 WO PCT/US2021/034852 patent/WO2021243204A1/en unknown
- 2021-05-28 PE PE2022002743A patent/PE20230460A1/es unknown
- 2021-05-28 IL IL298668A patent/IL298668A/en unknown
- 2021-05-28 BR BR112022024339A patent/BR112022024339A2/pt unknown
- 2021-05-28 JP JP2022573152A patent/JP2023528375A/ja active Pending
- 2021-05-28 MX MX2022014736A patent/MX2022014736A/es unknown
- 2021-05-28 CA CA3178417A patent/CA3178417A1/en active Pending
- 2021-05-28 EP EP21735037.0A patent/EP4157461A1/en active Pending
- 2021-05-28 KR KR1020227045305A patent/KR20230018425A/ko unknown
- 2021-05-28 CN CN202180038994.4A patent/CN116323665A/zh active Pending
- 2021-05-28 CR CR20220608A patent/CR20220608A/es unknown
- 2021-05-28 US US17/333,963 patent/US11787861B2/en active Active
- 2021-05-31 AR ARP210101465A patent/AR122213A1/es unknown
- 2021-05-31 TW TW110119701A patent/TW202210512A/zh unknown
-
2022
- 2022-11-23 CL CL2022003296A patent/CL2022003296A1/es unknown
- 2022-11-24 CO CONC2022/0016860A patent/CO2022016860A2/es unknown
-
2023
- 2023-08-24 US US18/455,181 patent/US20240018239A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2021243204A1 (en) | 2021-12-02 |
PE20230460A1 (es) | 2023-03-10 |
CA3178417A1 (en) | 2021-12-02 |
CR20220608A (es) | 2023-01-26 |
CN116323665A (zh) | 2023-06-23 |
TW202210512A (zh) | 2022-03-16 |
CO2022016860A2 (es) | 2023-02-27 |
WO2021243204A9 (en) | 2022-01-20 |
CL2022003296A1 (es) | 2023-04-14 |
AU2021281417A1 (en) | 2022-12-08 |
KR20230018425A (ko) | 2023-02-07 |
US20240018239A1 (en) | 2024-01-18 |
US11787861B2 (en) | 2023-10-17 |
BR112022024339A2 (pt) | 2022-12-27 |
JP2023528375A (ja) | 2023-07-04 |
US20210371521A1 (en) | 2021-12-02 |
AR122213A1 (es) | 2022-08-24 |
IL298668A (en) | 2023-01-01 |
EP4157461A1 (en) | 2023-04-05 |
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