|
PT1523496E
(pt)
|
2002-07-18 |
2011-09-29 |
Merus B V |
Produção de misturas de anticorpos de forma recombinante
|
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
|
EP1639009B1
(en)
|
2003-05-30 |
2013-02-27 |
Merus B.V. |
Fab library for the preparation of a mixture of antibodies
|
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
|
JP5620626B2
(ja)
|
2005-03-31 |
2014-11-05 |
中外製薬株式会社 |
会合制御によるポリペプチド製造方法
|
|
EP4218801A3
(en)
|
2006-03-31 |
2023-08-23 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody modification method for purifying bispecific antibody
|
|
CA2647846C
(en)
|
2006-03-31 |
2016-06-21 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for controlling blood pharmacokinetics of antibodies
|
|
ME02371B
(me)
|
2006-09-29 |
2016-06-20 |
Oncomed Pharm Inc |
Sastojci i postupci za dijagnstikovanje i tretman raka
|
|
CN105061577A
(zh)
|
2006-12-14 |
2015-11-18 |
爱勒让治疗公司 |
双巯基大环化系统
|
|
CN104086641A
(zh)
|
2007-02-23 |
2014-10-08 |
爱勒让治疗公司 |
三唑大环系统
|
|
CA2682174C
(en)
|
2007-03-28 |
2021-04-06 |
President And Fellows Of Harvard College |
Stitched polypeptides
|
|
EP2139924B1
(en)
|
2007-03-29 |
2016-07-06 |
Genmab A/S |
Bispecific antibodies and methods for production thereof
|
|
WO2009041613A1
(ja)
|
2007-09-26 |
2009-04-02 |
Chugai Seiyaku Kabushiki Kaisha |
抗体定常領域改変体
|
|
PL2202245T3
(pl)
|
2007-09-26 |
2017-02-28 |
Chugai Seiyaku Kabushiki Kaisha |
Sposób modyfikowania punktu izoelektrycznego przeciwciała poprzez podstawienie aminokwasu w cdr
|
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
|
PT2235064E
(pt)
*
|
2008-01-07 |
2016-03-01 |
Amgen Inc |
Método de preparação de moléculas heterodiméricas de fc de anticorpos utilizando efeitos de indução eletrostática
|
|
SG190572A1
(en)
|
2008-04-29 |
2013-06-28 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
SG191639A1
(en)
|
2008-06-03 |
2013-07-31 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
EP2315602A4
(en)
|
2008-06-26 |
2011-11-02 |
Acceleron Pharma Inc |
METHOD OF DOSING AN ACTRIIB ANTAGONIST AND MONITORING TREATED PATIENTS
|
|
MX2010014574A
(es)
|
2008-07-08 |
2011-04-27 |
Abbott Lab |
Inmunoglobulinas de dominio variable dual para prostaglandina e2 y usos de las mismas.
|
|
WO2010019702A2
(en)
|
2008-08-12 |
2010-02-18 |
Oncomed Pharmaceuticals, Inc. |
Ddr1-binding agents and methods of use thereof
|
|
US9175047B2
(en)
|
2009-01-14 |
2015-11-03 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles
|
|
JP5766124B2
(ja)
|
2009-01-21 |
2015-08-19 |
アムジェン インコーポレイテッド |
炎症性疾患および自己免疫疾患の処置の組成物および方法
|
|
SG172977A1
(en)
*
|
2009-01-26 |
2011-08-29 |
Genmab As |
Methods for producing mixtures of antibodies
|
|
US9228017B2
(en)
|
2009-03-19 |
2016-01-05 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
|
US20120071634A1
(en)
|
2009-03-19 |
2012-03-22 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody Constant Region Variant
|
|
AR075925A1
(es)
|
2009-03-25 |
2011-05-04 |
Genentech Inc |
Anticuerpos anti-alfa5beta1 (alfa5beta1: glicoproteina integrina) y sus usos
|
|
ES2537100T3
(es)
|
2009-04-07 |
2015-06-02 |
Roche Glycart Ag |
Anticuerpos biespecíficos trivalentes
|
|
CA2759233C
(en)
*
|
2009-04-27 |
2019-07-16 |
Oncomed Pharmaceuticals, Inc. |
Method for making heteromultimeric molecules
|
|
AU2013203859B2
(en)
*
|
2009-04-27 |
2016-09-08 |
Oncomed Pharmaceuticals, Inc. |
Method for making heteromultimeric molecules
|
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
|
KR20120027055A
(ko)
|
2009-06-26 |
2012-03-20 |
리제네론 파라마큐티칼스 인코포레이티드 |
천연 면역글로불린 포맷을 가지는 용이하게 분리된 이중특이성 항체
|
|
CA2766166A1
(en)
|
2009-07-08 |
2011-01-13 |
Amgen Inc. |
Design of stable and aggregation free antibody fc molecules through ch3 domain interface engineering
|
|
TW201109438A
(en)
*
|
2009-07-29 |
2011-03-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
WO2011028952A1
(en)
*
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
JP6091894B2
(ja)
|
2009-09-16 |
2017-03-15 |
ジェネンテック， インコーポレイテッド |
コイルドコイルおよび／またはテザー含有タンパク質複合体およびその使用
|
|
AU2010298338A1
(en)
|
2009-09-22 |
2012-04-12 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles
|
|
WO2011037158A1
(ja)
|
2009-09-24 |
2011-03-31 |
中外製薬株式会社 |
抗体定常領域改変体
|
|
AR078651A1
(es)
|
2009-10-15 |
2011-11-23 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
US8883145B2
(en)
|
2009-10-16 |
2014-11-11 |
Oncomed Pharmaceuticals, Inc. |
Methods of treatment with DLL4 antagonists and an anti-hypertensive agent
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
ES2688978T3
(es)
|
2009-11-23 |
2018-11-07 |
Amgen Inc. |
Anticuerpo monomérico Fc
|
|
WO2011090762A1
(en)
*
|
2009-12-29 |
2011-07-28 |
Emergent Product Development Seattle, Llc |
Heterodimer binding proteins and uses thereof
|
|
PL3095871T3
(pl)
|
2010-02-08 |
2019-10-31 |
Regeneron Pharma |
Mysz zawierająca wspólny łańcuch lekki
|
|
US9796788B2
(en)
|
2010-02-08 |
2017-10-24 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
|
US20130045492A1
(en)
|
2010-02-08 |
2013-02-21 |
Regeneron Pharmaceuticals, Inc. |
Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
|
|
WO2011103242A1
(en)
|
2010-02-18 |
2011-08-25 |
Genentech, Inc. |
Neuregulin antagonists and use thereof in treating cancer
|
|
US10435458B2
(en)
|
2010-03-04 |
2019-10-08 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variants with reduced Fcgammar binding
|
|
CA2791991A1
(en)
|
2010-03-24 |
2011-09-29 |
Genentech, Inc. |
Anti-lrp6 antibodies
|
|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
|
US20150231215A1
(en)
|
2012-06-22 |
2015-08-20 |
Randolph J. Noelle |
VISTA Antagonist and Methods of Use
|
|
US10745467B2
(en)
|
2010-03-26 |
2020-08-18 |
The Trustees Of Dartmouth College |
VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
|
|
EP2552947A4
(en)
|
2010-03-26 |
2013-11-13 |
Dartmouth College |
VISTA REGULATORY T CELL MEDIATOR PROTEIN, VISTA BINDING ACTIVE SUBSTANCES AND USE THEREOF
|
|
EP2556086B1
(en)
|
2010-04-09 |
2015-03-04 |
Amgen Inc. |
Btnl9 proteins, nucleic acids, and antibodies and uses thereof
|
|
AU2013203221B2
(en)
*
|
2010-04-20 |
2016-06-02 |
Genmab A/S |
Heterodimeric antibody FC-containing proteins and methods for production thereof
|
|
AU2016219622A1
(en)
*
|
2010-04-20 |
2016-09-15 |
Genmab A/S |
Heterodimeric antibody FC-containing proteins and methods for production thereof
|
|
JP2019048814A
(ja)
*
|
2010-04-20 |
2019-03-28 |
ゲンマブ エー／エス |
ヘテロ二量体抗体Ｆｃ含有タンパク質およびその産生方法
|
|
CA2796181C
(en)
*
|
2010-04-20 |
2023-01-03 |
Genmab A/S |
Heterodimeric antibody fc-containing proteins and methods for production thereof
|
|
RU2624027C2
(ru)
|
2010-04-23 |
2017-06-30 |
Дженентек, Инк. |
Получение гетеромультимерных белков
|
|
JP6022444B2
(ja)
*
|
2010-05-14 |
2016-11-09 |
ライナット ニューロサイエンス コーポレイション |
ヘテロ二量体タンパク質ならびにそれを生産および精製するための方法
|
|
WO2011147834A1
(en)
|
2010-05-26 |
2011-12-01 |
Roche Glycart Ag |
Antibodies against cd19 and uses thereof
|
|
CN107253992B
(zh)
|
2010-05-27 |
2022-03-11 |
根马布股份公司 |
针对her2的单克隆抗体
|
|
RU2577986C2
(ru)
|
2010-06-18 |
2016-03-20 |
Дженентек, Инк. |
Антитела против axl и способы их применения
|
|
WO2011161119A1
(en)
|
2010-06-22 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Antibodies against insulin-like growth factor i receptor and uses thereof
|
|
WO2011161189A1
(en)
|
2010-06-24 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Anti-hepsin antibodies and methods of use
|
|
NZ605449A
(en)
|
2010-07-09 |
2015-03-27 |
Genentech Inc |
Anti-neuropilin antibodies and methods of use
|
|
AU2011281702A1
(en)
|
2010-07-19 |
2013-01-31 |
F. Hoffmann-La Roche Ag |
Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
|
|
EP2596362A1
(en)
|
2010-07-19 |
2013-05-29 |
F. Hoffmann-La Roche AG |
Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
|
|
WO2012010582A1
(en)
|
2010-07-21 |
2012-01-26 |
Roche Glycart Ag |
Anti-cxcr5 antibodies and methods of use
|
|
WO2012016227A2
(en)
|
2010-07-29 |
2012-02-02 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
|
CA2807014A1
(en)
|
2010-08-03 |
2012-02-09 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
JP2013541501A
(ja)
|
2010-08-03 |
2013-11-14 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
慢性リンパ性白血病（ｃｌｌ）のバイオマーカー
|
|
WO2012017003A1
(en)
|
2010-08-05 |
2012-02-09 |
F. Hoffmann-La Roche Ag |
Anti-mhc antibody anti-viral cytokine fusion protein
|
|
NO2603530T3
(cg-RX-API-DMAC7.html)
|
2010-08-13 |
2018-04-07 |
|
|
|
JP5841149B2
(ja)
|
2010-08-13 |
2016-01-13 |
ロシュ グリクアート アーゲー |
抗テネイシンｃａ２抗体及び使用の方法
|
|
WO2012021875A1
(en)
|
2010-08-13 |
2012-02-16 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles with triazole linkers
|
|
RU2013110874A
(ru)
|
2010-08-25 |
2014-09-27 |
Ф.Хоффманн-Ля Рош Аг |
Антитела против il-18r1 и их применения
|
|
CA2809433A1
(en)
|
2010-08-26 |
2012-03-01 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
JP2013537966A
(ja)
|
2010-08-31 |
2013-10-07 |
ジェネンテック， インコーポレイテッド |
バイオマーカー及び治療の方法
|
|
US8551479B2
(en)
|
2010-09-10 |
2013-10-08 |
Oncomed Pharmaceuticals, Inc. |
Methods for treating melanoma
|
|
ES2758994T3
(es)
|
2010-11-05 |
2020-05-07 |
Zymeworks Inc |
Diseño anticuerpo heterodimérico estable con mutaciones en el dominio Fc
|
|
KR20130133205A
(ko)
|
2010-11-10 |
2013-12-06 |
제넨테크, 인크. |
신경계 질환 면역요법을 위한 방법 및 조성물
|
|
CN103298937B
(zh)
|
2010-11-17 |
2016-05-25 |
中外制药株式会社 |
具有代替凝血因子viii的功能的功能的多特异性抗原结合分子
|
|
EP2643353A1
(en)
|
2010-11-24 |
2013-10-02 |
Novartis AG |
Multispecific molecules
|
|
SI2646470T1
(sl)
|
2010-11-30 |
2017-05-31 |
F. Hoffmann-La Roche Ag |
Protitelesa proti receptorjem antitransferina in njihova uporaba za prenos terapevtskega enoverižnega variabilnega fragmenta (scfv) prek krvno-možganske pregrade
|
|
TR201815863T4
(tr)
|
2010-11-30 |
2018-11-21 |
Chugai Pharmaceutical Co Ltd |
Sitotoksisiteyi indükleyen terapötik madde.
|
|
EP2652498B1
(en)
|
2010-12-16 |
2018-04-18 |
F.Hoffmann-La Roche Ag |
Diagnosis and treatments relating to th2 inhibition
|
|
KR20140014116A
(ko)
|
2010-12-20 |
2014-02-05 |
제넨테크, 인크. |
항-메소텔린 항체 및 면역접합체
|
|
US20120195910A1
(en)
|
2010-12-22 |
2012-08-02 |
Genentech, Inc. |
Anti-pcsk9 antibodies and methods of use
|
|
US10689447B2
(en)
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
|
CN103649117B
(zh)
|
2011-02-04 |
2016-09-14 |
霍夫曼-拉罗奇有限公司 |
Fc变体及其生成方法
|
|
HUE040326T2
(hu)
|
2011-02-10 |
2019-03-28 |
Roche Glycart Ag |
Mutáns interleukon-2 polipeptidek
|
|
WO2012116927A1
(en)
|
2011-02-28 |
2012-09-07 |
F. Hoffmann-La Roche Ag |
Monovalent antigen binding proteins
|
|
MX341921B
(es)
|
2011-02-28 |
2016-09-07 |
Hoffmann La Roche |
Proteinas de union a antigeno.
|
|
DK2681245T3
(en)
|
2011-03-03 |
2018-08-13 |
Zymeworks Inc |
MULTIVALENT HEAT-MULTIMED SCAFFOLD DESIGN AND CONSTRUCTIONS
|
|
CA2830254C
(en)
*
|
2011-03-16 |
2019-09-10 |
Amgen Inc. |
Fc variants
|
|
AU2012235758B2
(en)
*
|
2011-03-25 |
2015-05-07 |
IGI Therapeutics SA |
Hetero-dimeric immunoglobulins
|
|
EP3590965A1
(en)
|
2011-03-29 |
2020-01-08 |
Roche Glycart AG |
Antibody fc variants
|
|
EP2694551A1
(en)
|
2011-04-07 |
2014-02-12 |
Genentech, Inc. |
Anti-fgfr4 antibodies and methods of use
|
|
CN103533951B
(zh)
|
2011-04-08 |
2017-04-19 |
安姆根有限公司 |
使用生长分化因子15(gdf‑15)治疗或改善代谢障碍的方法
|
|
SI2697257T1
(sl)
|
2011-04-13 |
2017-02-28 |
Bristol-Myers Squibb Company |
FC fuzijski proteini, ki vsebujejo nove linkerje ali razmestitve
|
|
JP6177231B2
(ja)
*
|
2011-04-20 |
2017-08-09 |
ゲンマブ エー／エス |
Ｈｅｒ２に対する二重特異性抗体
|
|
EP4520771A3
(en)
|
2011-04-20 |
2025-07-16 |
Genmab A/S |
Bispecifc antibodies against her2
|
|
CN103796677B
(zh)
|
2011-04-20 |
2019-08-16 |
健玛保 |
针对her2和cd3的双特异性抗体
|
|
CN103502273A
(zh)
|
2011-04-20 |
2014-01-08 |
罗氏格黎卡特股份公司 |
用于pH依赖性通过血脑屏障的方法和构建体
|
|
EA201892619A1
(ru)
|
2011-04-29 |
2019-04-30 |
Роше Гликарт Аг |
Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
|
|
MX2013013054A
(es)
|
2011-05-12 |
2014-02-20 |
Genentech Inc |
Metodo de monitoreo de lc-ms/ms de reaccion multiple para detectar anticuerpos terapeuticos en muestras de animales utilizando peptidos de firma de estructura.
|
|
PL2710035T3
(pl)
|
2011-05-16 |
2017-09-29 |
F.Hoffmann-La Roche Ag |
Agoniści fgfr1 i sposoby stosowania
|
|
BR112013032235A2
(pt)
|
2011-06-15 |
2016-11-22 |
Hoffmann La Roche |
anticorpos do receptor de epo anti-humano e métodos de uso
|
|
WO2013003680A1
(en)
|
2011-06-30 |
2013-01-03 |
Genentech, Inc. |
Anti-c-met antibody formulations
|
|
CN103827300A
(zh)
*
|
2011-06-30 |
2014-05-28 |
中外制药株式会社 |
异源二聚化多肽
|
|
UA117901C2
(uk)
|
2011-07-06 |
2018-10-25 |
Ґенмаб Б.В. |
Спосіб посилення ефекторної функції вихідного поліпептиду, його варіанти та їх застосування
|
|
EP2543680A1
(en)
*
|
2011-07-07 |
2013-01-09 |
Centre National de la Recherche Scientifique |
Multispecific mutated antibody Fab fragments
|
|
CN103930134B
(zh)
|
2011-07-18 |
2016-12-21 |
阿茨生物股份有限公司 |
长效促黄体激素(lh)化合物
|
|
CA2842099A1
(en)
*
|
2011-07-27 |
2013-01-31 |
Glaxo Group Limited |
Antigen binding constructs
|
|
IL273982B2
(en)
|
2011-08-05 |
2023-03-01 |
Regeneron Pharma |
Humanized mice possess a universal light chain
|
|
CA2842375A1
(en)
|
2011-08-17 |
2013-02-21 |
Erica Jackson |
Neuregulin antibodies and uses thereof
|
|
JP2014534806A
(ja)
|
2011-08-23 |
2014-12-25 |
ロシュ グリクアート アーゲー |
抗ｍｃｓｐ抗体
|
|
CA2844538C
(en)
|
2011-08-23 |
2020-09-22 |
Roche Glycart Ag |
Bispecific antigen binding molecules
|
|
US20130078250A1
(en)
|
2011-08-23 |
2013-03-28 |
Oliver Ast |
Bispecific t cell activating antigen binding molecules
|
|
MX356947B
(es)
|
2011-08-23 |
2018-06-20 |
Roche Glycart Ag |
Anticuerpos bioespecíficos específicos para antígenos que activan células t y un antígeno tumoral y métodos de uso.
|
|
EA030147B1
(ru)
|
2011-08-23 |
2018-06-29 |
Роше Гликарт Аг |
Биспецифические антигенсвязывающие молекулы, активирующие т-клетки
|
|
HK1199883A1
(en)
|
2011-08-26 |
2015-07-24 |
Merrimack Pharmaceuticals, Inc. |
Tandem fc bispecific antibodies
|
|
MX2014003094A
(es)
|
2011-09-15 |
2014-04-25 |
Genentech Inc |
Metodos para promover diferenciacion.
|
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
|
KR20140064971A
(ko)
|
2011-09-19 |
2014-05-28 |
제넨테크, 인크. |
c-met 길항제 및 B-raf 길항제를 포함하는 조합 치료
|
|
AP2014007588A0
(en)
|
2011-09-22 |
2014-04-30 |
Amgen Inc |
CD27L antigen binding proteins
|
|
CN107722122B
(zh)
|
2011-09-23 |
2022-05-27 |
昂考梅德药品有限公司 |
Vegf/dll4结合剂及其应用
|
|
CA2791109C
(en)
|
2011-09-26 |
2021-02-16 |
Merus B.V. |
Generation of binding molecules
|
|
BR112014008212A2
(pt)
|
2011-10-05 |
2017-06-13 |
Genentech Inc |
método para tratar uma condição hepática, método de indução por diferenciação hepática e método de redução de proliferação anormal do ducto biliar
|
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
PL2766397T3
(pl)
|
2011-10-11 |
2018-10-31 |
F.Hoffmann-La Roche Ag |
Ulepszone składanie przeciwciał bispecyficznych
|
|
ES2687951T3
(es)
|
2011-10-14 |
2018-10-30 |
F. Hoffmann-La Roche Ag |
Anticuerpos anti-HtrA1 y procedimientos de uso
|
|
BR112014008590A2
(pt)
|
2011-10-15 |
2017-10-24 |
Genentech Inc |
métodos de uso de antagonistas de scd1
|
|
CN108929375A
(zh)
|
2011-10-18 |
2018-12-04 |
爱勒让治疗公司 |
拟肽大环化合物
|
|
WO2013059531A1
(en)
|
2011-10-20 |
2013-04-25 |
Genentech, Inc. |
Anti-gcgr antibodies and uses thereof
|
|
WO2013060867A2
(en)
|
2011-10-27 |
2013-05-02 |
Genmab A/S |
Production of heterodimeric proteins
|
|
SG11201401815XA
(en)
|
2011-10-28 |
2014-05-29 |
Genentech Inc |
Therapeutic combinations and methods of treating melanoma
|
|
CN109111524B
(zh)
*
|
2011-10-31 |
2022-10-28 |
中外制药株式会社 |
控制了重链与轻链的缔合的抗原结合分子
|
|
WO2013063702A1
(en)
*
|
2011-11-04 |
2013-05-10 |
Zymeworks Inc. |
Stable heterodimeric antibody design with mutations in the fc domain
|
|
WO2013078170A1
(en)
|
2011-11-21 |
2013-05-30 |
Genentech, Inc. |
Purification of anti-c-met antibodies
|
|
MX2014006241A
(es)
|
2011-11-23 |
2015-03-03 |
Amgen Inc |
Metodos de tratamiento usando un anticuerpo contra interferon gamma.
|
|
EP2788024A1
(en)
|
2011-12-06 |
2014-10-15 |
F.Hoffmann-La Roche Ag |
Antibody formulation
|
|
CN104302665B
(zh)
|
2011-12-21 |
2019-04-23 |
安姆根有限公司 |
与新生儿Fc受体的结合增强的变体Fc多肽
|
|
EP3816284A1
(en)
|
2011-12-22 |
2021-05-05 |
F. Hoffmann-La Roche AG |
Expression vector for antibody production in eukaryotic cells
|
|
WO2013092720A1
(en)
|
2011-12-22 |
2013-06-27 |
F. Hoffmann-La Roche Ag |
Full length antibody display system for eukaryotic cells and its use
|
|
KR102166824B1
(ko)
|
2011-12-22 |
2020-10-19 |
에프. 호프만-라 로슈 아게 |
발현 벡터 구성원 조합, 신규한 제조 세포 생성 방법 및 폴리펩티드의 재조합적 제조를 위한 그의 용도
|
|
AR089434A1
(es)
|
2011-12-23 |
2014-08-20 |
Genentech Inc |
Procedimiento para preparar formulaciones con alta concentracion de proteinas
|
|
BR112014015851A2
(pt)
|
2011-12-30 |
2019-09-24 |
Abbvie Inc |
proteínas de ligação específicas duplas direcionadas contra il-13 e/ou il-17
|
|
CN102558355B
(zh)
*
|
2011-12-31 |
2015-02-25 |
苏州康宁杰瑞生物科技有限公司 |
基于电荷网络的异二聚体fc改造方法及异二聚体蛋白的制备方法
|
|
MX2014008157A
(es)
|
2012-01-18 |
2014-10-06 |
Genentech Inc |
Anticuerpos anti-lrp5 y metodos de uso.
|
|
JP2015506944A
(ja)
|
2012-01-18 |
2015-03-05 |
ジェネンテック， インコーポレイテッド |
Ｆｇｆ１９修飾薬を使用する方法
|
|
MX2014009129A
(es)
*
|
2012-01-26 |
2014-11-21 |
Amgen Inc |
Polipeptidos de factor 15 de diferenciacion de crecimiento (gdf-15).
|
|
EP2809682B1
(en)
|
2012-02-03 |
2020-04-08 |
F.Hoffmann-La Roche Ag |
Bispecific antibody molecules with antigen-transfected t-cells and their use in medicine
|
|
CN113480639A
(zh)
|
2012-02-09 |
2021-10-08 |
中外制药株式会社 |
抗体的Fc区变异体
|
|
RU2014133069A
(ru)
|
2012-02-11 |
2016-04-10 |
Дженентек, Инк. |
Транслокации r-спондина и способы с их использованием
|
|
BR112014018005B1
(pt)
|
2012-02-15 |
2021-06-29 |
F. Hoffmann-La Roche Ag |
Uso de um complexo não covalente imobilizado
|
|
CA2864120A1
(en)
|
2012-02-15 |
2013-08-22 |
Aileron Therapeutics, Inc. |
Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
|
|
CN112500466B
(zh)
|
2012-02-15 |
2022-05-03 |
艾瑞朗医疗公司 |
拟肽大环化合物
|
|
JP6254146B2
(ja)
|
2012-03-27 |
2017-12-27 |
エヌジーエム バイオファーマシューティカルス，インコーポレーテッド |
代謝障害を治療するための組成物および方法
|
|
RU2014136886A
(ru)
|
2012-03-27 |
2016-05-20 |
Дженентек, Инк. |
Диагностика и виды лечения, связанные с ингибиторами her3
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
MX2014011818A
(es)
|
2012-04-05 |
2014-12-10 |
Hoffmann La Roche |
Anticuerpos biespecificos contra inductor debil de la apoptosis relacionado con el tnf (tweak) humana e il17 humana y usos de los mismos.
|
|
ES2740749T3
(es)
|
2012-04-20 |
2020-02-06 |
Merus Nv |
Métodos y medios para la producción de moléculas heterodiméricas similares a Ig
|
|
US9212227B2
(en)
|
2012-04-30 |
2015-12-15 |
Janssen Biotech, Inc. |
ST2L antibody antagonists for the treatment of ST2L-mediated inflammatory pulmonary conditions
|
|
JP6242865B2
(ja)
|
2012-05-01 |
2017-12-06 |
ジェネンテック， インコーポレイテッド |
抗ｐｍｅｌ１７抗体および免疫複合体
|
|
CA2873720A1
(en)
*
|
2012-05-10 |
2013-11-14 |
Zymeworks Inc. |
Single-arm monovalent antibody constructs and uses thereof
|
|
CA2872540A1
(en)
*
|
2012-05-10 |
2013-11-14 |
Zymeworks Inc. |
Heteromultimer constructs of immunoglobulin heavy chains with mutations in the fc domain
|
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
|
AR091069A1
(es)
|
2012-05-18 |
2014-12-30 |
Amgen Inc |
Proteinas de union a antigeno dirigidas contra el receptor st2
|
|
CN108992668B
(zh)
|
2012-05-21 |
2023-12-05 |
霍夫曼-拉罗奇有限公司 |
用于提高血脑屏障转运的安全性的方法
|
|
RU2625771C2
(ru)
|
2012-05-23 |
2017-07-18 |
Дженентек, Инк. |
Способ отбора терапевтических средств
|
|
EP2862875B1
(en)
|
2012-06-14 |
2023-09-06 |
Chugai Seiyaku Kabushiki Kaisha |
ANTIGEN-BINDING MOLECULE CONTAINING MODIFIED Fc REGION
|
|
AR091462A1
(es)
|
2012-06-15 |
2015-02-04 |
Genentech Inc |
Anticuerpos anti-pcsk9, formulaciones, dosificacion y metodos de uso
|
|
DK3421486T5
(da)
|
2012-06-22 |
2024-09-16 |
The Trustees Of Darthmouth College |
Nye Vista-IG-konstruktioner og anvendelse af Vista-IG til behandling af autoimmune, allergiske og inflammatoriske lidelser
|
|
US9890215B2
(en)
|
2012-06-22 |
2018-02-13 |
King's College London |
Vista modulators for diagnosis and treatment of cancer
|
|
WO2014004586A1
(en)
|
2012-06-25 |
2014-01-03 |
Zymeworks Inc. |
Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
|
|
SI2869837T1
(sl)
|
2012-07-04 |
2016-12-30 |
F. Hoffmann-La Roche Ag |
Protitelesa proti teofilinu in postopki uporabe
|
|
CN104411725B
(zh)
|
2012-07-04 |
2018-09-28 |
弗·哈夫曼-拉罗切有限公司 |
抗生物素抗体及使用方法
|
|
CN107973856B
(zh)
|
2012-07-04 |
2021-11-23 |
弗·哈夫曼-拉罗切有限公司 |
共价连接的抗原-抗体缀合物
|
|
RU2670491C2
(ru)
|
2012-07-05 |
2018-10-23 |
Дженентек, Инк. |
Система экспрессии и секреции
|
|
AU2013285355A1
(en)
|
2012-07-06 |
2015-01-29 |
Genmab B.V. |
Dimeric protein with triple mutations
|
|
EP3632462A1
(en)
|
2012-07-06 |
2020-04-08 |
Genmab B.V. |
Dimeric protein with triple mutations
|
|
WO2014011520A1
(en)
|
2012-07-09 |
2014-01-16 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd22 antibodies
|
|
US20140030279A1
(en)
|
2012-07-09 |
2014-01-30 |
Spirogen Sarl |
Anti-cd22 antibodies and immunoconjugates
|
|
WO2014011519A1
(en)
|
2012-07-09 |
2014-01-16 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd79b antibodies
|
|
US20140030282A1
(en)
|
2012-07-09 |
2014-01-30 |
Genentech, Inc. |
Anti-cd79b antibodies and immunoconjugates
|
|
JP2015528003A
(ja)
*
|
2012-07-13 |
2015-09-24 |
ザイムワークス，インコーポレイテッド |
抗ｃｄ３構築物を含む二重特異性の非対称ヘテロ二量体
|
|
US9695233B2
(en)
|
2012-07-13 |
2017-07-04 |
Roche Glycart Ag |
Bispecific anti-VEGF/anti-ANG-2 antibodies and their use in the treatment of ocular vascular diseases
|
|
KR20150029714A
(ko)
|
2012-07-13 |
2015-03-18 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
이중특이적 항체의 공-도입에 의한 ｃａｒ 세포의 활성 증강
|
|
CA2878640C
(en)
|
2012-07-13 |
2023-10-24 |
Zymeworks Inc. |
Multivalent heteromultimer scaffold design and constructs
|
|
EP2875046B2
(en)
|
2012-07-19 |
2025-04-30 |
Amgen Inc. |
Human btnl3 proteins, nucleic acids, and antibodies and uses thereof
|
|
CN102851338A
(zh)
*
|
2012-07-25 |
2013-01-02 |
苏州康宁杰瑞生物科技有限公司 |
利用电荷排斥作用制备同二聚体蛋白混合物的方法
|
|
AR092044A1
(es)
|
2012-08-07 |
2015-03-18 |
Roche Glycart Ag |
Inmunoterapia mejorada
|
|
BR112015002790A2
(pt)
|
2012-08-09 |
2017-08-08 |
Roche Glycart Ag |
anticorpos asgpr e usos dos mesmos.
|
|
SG10201709559PA
(en)
|
2012-08-24 |
2017-12-28 |
Chugai Pharmaceutical Co Ltd |
Fcγriib-specific fc region variant
|
|
EP2889376A4
(en)
|
2012-08-24 |
2016-11-02 |
Chugai Pharmaceutical Co Ltd |
ANTIBODIES Fc SPECIFIC TO FCTRII OF MOUSE
|
|
CA2884704C
(en)
|
2012-09-07 |
2023-04-04 |
Randolph J. Noelle |
Vista modulators for diagnosis and treatment of cancer
|
|
AU2013322710A1
(en)
|
2012-09-25 |
2015-04-16 |
Glenmark Pharmaceuticals S.A. |
Purification of hetero-dimeric immunoglobulins
|
|
DK2900694T3
(en)
|
2012-09-27 |
2018-11-19 |
Merus Nv |
BISPECIFIC IGG ANTIBODIES AS T-CELL ACTIVATORS
|
|
JP6581505B2
(ja)
|
2012-10-03 |
2019-09-25 |
ザイムワークス，インコーポレイテッド |
重鎖および軽鎖ポリペプチドの対を定量化する方法
|
|
JP6273205B2
(ja)
|
2012-10-05 |
2018-01-31 |
協和発酵キリン株式会社 |
ヘテロダイマータンパク質組成物
|
|
US10087250B2
(en)
|
2012-10-08 |
2018-10-02 |
Roche Glycart Ag |
Fc-free antibodies comprising two fab-fragments and methods of use
|
|
AU2013337811A1
(en)
|
2012-10-31 |
2015-05-14 |
Oncomed Pharmaceuticals, Inc. |
Methods and monitoring of treatment with a DLL4 antagonist
|
|
CN104812384B
(zh)
|
2012-11-01 |
2020-09-18 |
爱勒让治疗公司 |
二取代的氨基酸及其制备和使用方法
|
|
BR112015009961B1
(pt)
|
2012-11-01 |
2020-10-20 |
Abbvie Inc. |
proteína de ligação capaz de se ligar a dll4 e vegf, bem como composição que a compreende como composição que a compreende
|
|
US11230589B2
(en)
|
2012-11-05 |
2022-01-25 |
Foundation Medicine, Inc. |
Fusion molecules and uses thereof
|
|
EP2914621B1
(en)
|
2012-11-05 |
2023-06-07 |
Foundation Medicine, Inc. |
Novel ntrk1 fusion molecules and uses thereof
|
|
CN110669136A
(zh)
|
2012-11-05 |
2020-01-10 |
全药工业株式会社 |
抗体或抗体组合物的制备方法
|
|
MA38165A1
(fr)
|
2012-11-08 |
2018-07-31 |
Hoffmann La Roche |
Protéines de liaison à l'antigène her3 se liant à l'épingle à cheveux beta de her3
|
|
JP6386465B2
(ja)
|
2012-11-13 |
2018-09-05 |
ジェネンテック， インコーポレイテッド |
抗ヘマグルチニン抗体及び使用方法
|
|
CN112079929A
(zh)
|
2012-11-21 |
2020-12-15 |
武汉友芝友生物制药有限公司 |
双特异性抗体
|
|
UY35148A
(es)
*
|
2012-11-21 |
2014-05-30 |
Amgen Inc |
Immunoglobulinas heterodiméricas
|
|
EP3878964A1
(en)
|
2012-11-27 |
2021-09-15 |
Ajou University Industry-Academic Cooperation Foundation |
Ch3 domain variant pair inducing formation of heterodimer of heavy chain constant region of antibody at high efficiency, method for preparing same, and use thereof
|
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
|
KR102545617B1
(ko)
|
2012-11-28 |
2023-06-20 |
자임워크스 비씨 인코포레이티드 |
가공된 면역글로불린 중쇄-경쇄 쌍 및 이들의 용도
|
|
KR102249779B1
(ko)
|
2012-12-27 |
2021-05-07 |
추가이 세이야쿠 가부시키가이샤 |
헤테로이량화 폴리펩티드
|
|
US20150353636A1
(en)
|
2013-01-10 |
2015-12-10 |
Genmab B.V. |
Human igg1 fc region variants and uses thereof
|
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
|
HRP20191865T1
(hr)
*
|
2013-01-14 |
2020-01-10 |
Xencor, Inc. |
Novi heterodimerni proteini
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
CA2897987A1
(en)
|
2013-01-15 |
2014-07-24 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
|
US10980804B2
(en)
|
2013-01-18 |
2021-04-20 |
Foundation Medicine, Inc. |
Methods of treating cholangiocarcinoma
|
|
WO2014116749A1
(en)
|
2013-01-23 |
2014-07-31 |
Genentech, Inc. |
Anti-hcv antibodies and methods of using thereof
|
|
ES2728936T3
(es)
|
2013-01-25 |
2019-10-29 |
Amgen Inc |
Anticuerpos dirigidos contra CDH19 para melanoma
|
|
EP2950807B1
(en)
|
2013-01-30 |
2018-03-28 |
NGM Biopharmaceuticals, Inc. |
Compositions and methods of use in treating metabolic disorders
|
|
US9161966B2
(en)
|
2013-01-30 |
2015-10-20 |
Ngm Biopharmaceuticals, Inc. |
GDF15 mutein polypeptides
|
|
US10047163B2
(en)
|
2013-02-08 |
2018-08-14 |
Abbvie Stemcentrx Llc |
Multispecific constructs
|
|
ES2813501T3
(es)
|
2013-02-12 |
2021-03-24 |
Bristol Myers Squibb Co |
Métodos de replegado de proteínas basados en filtración de flujo tangencial
|
|
EP3617220B1
(en)
|
2013-02-12 |
2021-03-24 |
Bristol-Myers Squibb Company |
High ph protein refolding methods
|
|
WO2014126582A1
(en)
*
|
2013-02-15 |
2014-08-21 |
R-PHARM, CJSC (Closed Joint Stock Company) |
IL-1β INHIBITOR COMPOSITION AND USE THEREOF
|
|
HK1211235A1
(en)
|
2013-02-22 |
2016-05-20 |
霍夫曼-拉罗奇有限公司 |
Methods of treating cancer and preventing drug resistance
|
|
EP2961770A1
(en)
|
2013-02-26 |
2016-01-06 |
Roche Glycart AG |
Bispecific t cell activating antigen binding molecules
|
|
EP2961772A1
(en)
|
2013-02-26 |
2016-01-06 |
Roche Glycart AG |
Anti-mcsp antibodies
|
|
KR20180023035A
(ko)
|
2013-02-26 |
2018-03-06 |
로슈 글리카트 아게 |
이중특이적 t 세포 활성화 항원 결합 분자
|
|
WO2014131694A1
(en)
|
2013-02-26 |
2014-09-04 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
|
MX2015011428A
(es)
|
2013-03-06 |
2016-02-03 |
Genentech Inc |
Metodos para tratar y prevenir la resistencia a los farmacos para el cancer.
|
|
KR20150143458A
(ko)
|
2013-03-06 |
2015-12-23 |
메리맥 파마슈티컬즈, 인크. |
항-C-MET 탠덤 Fc 이중특이적 항체
|
|
CA3085446C
(en)
*
|
2013-03-13 |
2022-08-09 |
Ibentrus, Inc. |
Protein in which electrostatic interaction is introduced within hydrophobic interaction site and preparation method thereof
|
|
PH12022550138A1
(en)
|
2013-03-13 |
2023-03-06 |
Amgen Inc |
Proteins specific for baff and b7rp1 and uses thereof
|
|
US9458246B2
(en)
|
2013-03-13 |
2016-10-04 |
Amgen Inc. |
Proteins specific for BAFF and B7RP1
|
|
CA2905070A1
(en)
|
2013-03-14 |
2014-09-25 |
Genentech, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
WO2014152358A2
(en)
|
2013-03-14 |
2014-09-25 |
Genentech, Inc. |
Combinations of a mek inhibitor compound with an her3/egfr inhibitor compound and methods of use
|
|
US9546203B2
(en)
|
2013-03-14 |
2017-01-17 |
Amgen Inc. |
Aglycosylated Fc-containing polypeptides with cysteine substitutions
|
|
EP2970474B1
(en)
|
2013-03-14 |
2017-12-20 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
|
US20160143910A1
(en)
|
2013-03-15 |
2016-05-26 |
Constellation Pharmaceuticals, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
|
HK1211963A1
(en)
|
2013-03-15 |
2016-06-03 |
豪夫迈．罗氏有限公司 |
Compositions and methods for diagnosis and treatment of hepatic cancers
|
|
CA2906526C
(en)
|
2013-03-15 |
2022-12-06 |
Ellen Chi |
Interferon alpha and omega antibody antagonists
|
|
MX2015013166A
(es)
|
2013-03-15 |
2015-12-11 |
Abbvie Inc |
Proteinas de union especificas duales dirigidas contra il-1 beta y/o il-17.
|
|
DK2970486T3
(en)
|
2013-03-15 |
2018-08-06 |
Xencor Inc |
MODULATION OF T-CELLS WITH BISPECIFIC ANTIBODIES AND FC-FUSIONS
|
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
|
KR102233349B1
(ko)
|
2013-03-15 |
2021-03-31 |
에이씨 이뮨 에스.에이. |
항-타우(tau) 항체 및 사용 방법
|
|
LT2951203T
(lt)
*
|
2013-03-15 |
2019-09-10 |
Xencor, Inc. |
Heterodimeriniai baltymai
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
BR112015021521A2
(pt)
|
2013-03-15 |
2017-10-10 |
Genentech Inc |
anticorpos anti-crth2 e métodos para seu uso
|
|
MY176706A
(en)
|
2013-03-15 |
2020-08-19 |
Genentech Inc |
Biomarkers and methods of treating pd-1 and pd-l1 related conditions
|
|
US20140302037A1
(en)
*
|
2013-03-15 |
2014-10-09 |
Amgen Inc. |
BISPECIFIC-Fc MOLECULES
|
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
|
EP3424952A1
(en)
|
2013-03-15 |
2019-01-09 |
Amgen, Inc |
Heterodimeric bispecific antibodies
|
|
JP2016515544A
(ja)
|
2013-03-18 |
2016-05-30 |
バイオセルオーエックス プロダクツ ビー．ブイ． |
ヒト化抗ｃｄ１３４（ｏｘ４０）抗体およびその使用
|
|
CN105246914B
(zh)
|
2013-04-02 |
2021-08-27 |
中外制药株式会社 |
Fc区变体
|
|
UA118028C2
(uk)
|
2013-04-03 |
2018-11-12 |
Рош Глікарт Аг |
Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування
|
|
CN105164157B
(zh)
*
|
2013-04-29 |
2024-05-28 |
豪夫迈·罗氏有限公司 |
Fc-受体结合的修饰的非对称抗体及使用方法
|
|
UA118029C2
(uk)
|
2013-04-29 |
2018-11-12 |
Ф. Хоффманн-Ля Рош Аг |
Модифіковане антитіло, що зв'язується з людським fcrn, й способи його застосування
|
|
PE20151925A1
(es)
|
2013-04-29 |
2015-12-26 |
Hoffmann La Roche |
Anticuerpos anti-igf-1r con abolicion de la union al fcrn y su utilizacion en el tratamiento de enfermedades oculares vasculares
|
|
WO2014182970A1
(en)
|
2013-05-08 |
2014-11-13 |
Zymeworks Inc. |
Bispecific her2 and her3 antigen binding constructs
|
|
IL242088B2
(en)
|
2013-05-20 |
2023-12-01 |
Genentech Inc |
Anti-transferrin receptor antibodies and methods of use
|
|
EP3456743B1
(en)
|
2013-05-30 |
2021-08-18 |
Kiniksa Pharmaceuticals, Ltd. |
Oncostatin m receptor antigen binding proteins
|
|
IL311371B2
(en)
|
2013-07-05 |
2024-09-01 |
Genmab As |
CD3 antibodies of human origin or chimeras
|
|
LT3027642T
(lt)
|
2013-07-31 |
2020-10-12 |
Amgen Inc. |
Augimo ir diferenciacijos faktoriaus 15(gdf-15) konstruktai
|
|
EP3041862B1
(en)
*
|
2013-09-05 |
2020-05-06 |
IGM Biosciences, Inc. |
Constant chain modified bispecific, penta- and hexavalent ig-m antibodies
|
|
KR20160055252A
(ko)
|
2013-09-17 |
2016-05-17 |
제넨테크, 인크. |
항-lgr5 항체의 사용 방법
|
|
WO2015048272A1
(en)
|
2013-09-25 |
2015-04-02 |
Amgen Inc. |
V-c-fc-v-c antibody
|
|
CN105764922B
(zh)
*
|
2013-09-27 |
2020-07-17 |
中外制药株式会社 |
多肽异源多聚体的制备方法
|
|
KR20160044060A
(ko)
|
2013-10-11 |
2016-04-22 |
에프. 호프만-라 로슈 아게 |
다중특이적 도메인 교환된 통상의 가변 경쇄 항체
|
|
CA2926084A1
(en)
|
2013-10-11 |
2015-04-16 |
Genentech, Inc. |
Nsp4 inhibitors and methods of use
|
|
TWI658052B
(zh)
|
2013-10-18 |
2019-05-01 |
美商建南德克公司 |
抗－ｒｓｐｏ抗體及使用方法
|
|
CA2924873A1
(en)
|
2013-10-23 |
2015-04-30 |
Genentech, Inc. |
Methods of diagnosing and treating eosinophilic disorders
|
|
EA034655B1
(ru)
|
2013-11-06 |
2020-03-03 |
Янссен Байотек, Инк. |
Антитела к ccl17
|
|
WO2015073721A1
(en)
|
2013-11-13 |
2015-05-21 |
Zymeworks Inc. |
Monovalent antigen binding constructs targeting egfr and/or her2 and uses thereof
|
|
CA2924268C
(en)
|
2013-11-21 |
2021-05-18 |
F. Hoffmann-La Roche Ag |
Anti-alpha-synuclein antibodies and methods of use
|
|
CA2931356A1
(en)
|
2013-11-27 |
2015-06-04 |
Zymeworks Inc. |
Bispecific antigen-binding constructs targeting her2
|
|
MA39095A1
(fr)
|
2013-12-13 |
2018-08-31 |
Genentech Inc |
Anticorps et immunoconjugués anti-cd33
|
|
SG11201605044RA
(en)
|
2013-12-20 |
2016-07-28 |
Hoffmann La Roche |
HUMANIZED ANTI-Tau(pS422) ANTIBODIES AND METHODS OF USE
|
|
TWI728373B
(zh)
|
2013-12-23 |
2021-05-21 |
美商建南德克公司 |
抗體及使用方法
|
|
IL301714A
(en)
|
2013-12-24 |
2023-05-01 |
Janssen Pharmaceutica Nv |
Antibodies and anti-VISTA fragments
|
|
US11014987B2
(en)
|
2013-12-24 |
2021-05-25 |
Janssen Pharmaceutics Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
|
EP3089759B1
(en)
|
2014-01-03 |
2018-12-05 |
F. Hoffmann-La Roche AG |
Covalently linked polypeptide toxin-antibody conjugates
|
|
RU2693438C2
(ru)
|
2014-01-03 |
2019-07-02 |
Ф. Хоффманн-Ля Рош Аг |
Биспецифичные антитела против гаптена/против рецептора гематоэнцефалического барьера, их комплексы и их применение в качестве челноков гематоэнцефалического барьера
|
|
RU2694981C2
(ru)
|
2014-01-03 |
2019-07-18 |
Ф. Хоффманн-Ля Рош Аг |
Ковалентно связанные конъюгаты хеликар-антитело против хеликара и их применения
|
|
JP6557664B2
(ja)
|
2014-01-06 |
2019-08-07 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
一価の血液脳関門シャトルモジュール
|
|
US10206980B2
(en)
|
2014-01-08 |
2019-02-19 |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
IL-15 heterodimeric protein and uses thereof
|
|
RU2727639C2
(ru)
|
2014-01-15 |
2020-07-22 |
Ф.Хоффманн-Ля Рош Аг |
Варианты fc-области с модифицированной способностью связываться с fcrn и с сохраненной способностью связываться с белком а
|
|
CN110981957B
(zh)
|
2014-01-15 |
2024-12-24 |
豪夫迈·罗氏有限公司 |
具有改善的蛋白A结合作用的Fc区变体
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
EP3096797A1
(en)
|
2014-01-24 |
2016-11-30 |
F. Hoffmann-La Roche AG |
Methods of using anti-steap1 antibodies and immunoconjugates
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
SG11201606490YA
(en)
|
2014-02-08 |
2016-09-29 |
Genentech Inc |
Methods of treating alzheimer's disease
|
|
NZ723884A
(en)
|
2014-02-08 |
2023-02-24 |
Genentech Inc |
Methods of treating alzheimer’s disease
|
|
CA2936565C
(en)
|
2014-02-12 |
2020-08-11 |
Genentech, Inc. |
Anti-jagged1 antibodies and methods of use
|
|
EP3107574A2
(en)
|
2014-02-21 |
2016-12-28 |
F. Hoffmann-La Roche AG |
Anti-il-13/il-17 bispecific antibodies and uses thereof
|
|
US9732154B2
(en)
|
2014-02-28 |
2017-08-15 |
Janssen Biotech, Inc. |
Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
|
|
DK3805268T3
(da)
|
2014-02-28 |
2025-01-20 |
Merus Nv |
Antistof, der binder erbb-2 og erbb-3
|
|
US10844127B2
(en)
|
2014-02-28 |
2020-11-24 |
Merus N.V. |
Antibodies that bind EGFR and ErbB3
|
|
KR102442436B1
(ko)
|
2014-03-14 |
2022-09-15 |
노파르티스 아게 |
Lag-3에 대한 항체 분자 및 그의 용도
|
|
KR102561695B1
(ko)
|
2014-03-14 |
2023-07-28 |
제넨테크, 인크. |
이형 폴리펩티드의 분비를 위한 방법 및 조성물
|
|
JP2017513818A
(ja)
|
2014-03-15 |
2017-06-01 |
ノバルティス アーゲー |
キメラ抗原受容体を使用する癌の処置
|
|
WO2015140591A1
(en)
|
2014-03-21 |
2015-09-24 |
Nordlandssykehuset Hf |
Anti-cd14 antibodies and uses thereof
|
|
JP6636498B2
(ja)
|
2014-03-21 |
2020-01-29 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． |
単一ドメイン結合タンパク質を作る非ヒト動物
|
|
CA2943329A1
(en)
|
2014-03-24 |
2015-10-01 |
Genentech, Inc. |
Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
|
|
US12180264B2
(en)
|
2014-03-24 |
2024-12-31 |
R-Pharm Overseas, Inc. |
IL1-R1 derived inhibitor of IL-1β and use thereof
|
|
SG11201607983YA
(en)
|
2014-03-28 |
2016-10-28 |
Xencor Inc |
Bispecific antibodies that bind to cd38 and cd3
|
|
MX2016012779A
(es)
|
2014-03-31 |
2017-04-27 |
Genentech Inc |
Terapia de combinacion con agentes antiangiogénesis y agonistas de unión a ox40.
|
|
WO2015153513A1
(en)
|
2014-03-31 |
2015-10-08 |
Genentech, Inc. |
Anti-ox40 antibodies and methods of use
|
|
EP3825326A1
(en)
|
2014-04-01 |
2021-05-26 |
Adimab, LLC |
Multispecific antibody analogs comprising a common light chain, and methods of their preparation and use
|
|
UA117289C2
(uk)
*
|
2014-04-02 |
2018-07-10 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифічне антитіло
|
|
EP3126389B1
(en)
|
2014-04-02 |
2024-10-23 |
F. Hoffmann-La Roche AG |
Method for detecting multispecific antibody light chain mispairing
|
|
KR102568808B1
(ko)
|
2014-04-07 |
2023-08-18 |
추가이 세이야쿠 가부시키가이샤 |
면역활성화 항원 결합 분자
|
|
WO2015160940A1
(en)
*
|
2014-04-15 |
2015-10-22 |
President And Fellows Of Harvard College |
Bi-specific agents
|
|
WO2015164615A1
(en)
|
2014-04-24 |
2015-10-29 |
University Of Oslo |
Anti-gluten antibodies and uses thereof
|
|
SG10201913507SA
(en)
|
2014-05-02 |
2020-02-27 |
Momenta Pharmaceuticals Inc |
Compositions and methods related to engineered fc constructs
|
|
WO2015171822A1
(en)
|
2014-05-06 |
2015-11-12 |
Genentech, Inc. |
Production of heteromultimeric proteins using mammalian cells
|
|
JP7179400B2
(ja)
|
2014-05-13 |
2022-11-29 |
バイオアトラ インコーポレイテッド |
条件的活性型生物学的タンパク質
|
|
AU2015260230A1
(en)
|
2014-05-13 |
2016-11-17 |
Chugai Seiyaku Kabushiki Kaisha |
T cell-redirected antigen-binding molecule for cells having immunosuppression function
|
|
JP6868394B2
(ja)
*
|
2014-05-16 |
2021-05-12 |
ファイザー・インク |
二重特異性抗体
|
|
WO2015179658A2
(en)
|
2014-05-22 |
2015-11-26 |
Genentech, Inc. |
Anti-gpc3 antibodies and immunoconjugates
|
|
CA2944717A1
(en)
|
2014-05-23 |
2015-11-26 |
Genentech, Inc. |
Mit biomarkers and methods using the same
|
|
BR112016027888A2
(pt)
|
2014-05-28 |
2017-10-24 |
Zymeworks Inc |
construto de polipeptídeo de ligação ao antígeno isolado, polinucleotídeo isolado ou um conjunto de polinucleotídeos isolados, vetor ou conjunto de vetores, célula isolada, composição farmacêutica, uso do construto, método para tratar um sujeito com uma doença ou distúrbio, método para obter um construto, método para preparar um construto, meio de armazenamento legível por computador, método para produzir um construto de polipeptídeo de ligação com antígeno bi-específico e método para preparar um construto de polipeptídeo de ligação com antígeno isolado
|
|
US10010498B2
(en)
|
2014-06-04 |
2018-07-03 |
Acceleron Pharma Inc. |
Methods for treatment of amyotrophic lateral sclerosis with follistatin fusion proteins
|
|
EP3152237B1
(en)
|
2014-06-04 |
2020-04-01 |
Acceleron Pharma Inc. |
Methods and compositions for treatment of disorders with follistatin polypeptides
|
|
MX389695B
(es)
|
2014-06-11 |
2025-03-20 |
Kathy A Green |
Uso de agonistas y antagonistas vista para suprimir o aumentar la inmunidad humoral.
|
|
WO2015191715A1
(en)
|
2014-06-11 |
2015-12-17 |
Genentech, Inc. |
Anti-lgr5 antibodies and uses thereof
|
|
CN107073121A
(zh)
|
2014-06-13 |
2017-08-18 |
基因泰克公司 |
治疗及预防癌症药物抗性的方法
|
|
TWI713453B
(zh)
|
2014-06-23 |
2020-12-21 |
美商健生生物科技公司 |
干擾素α及ω抗體拮抗劑
|
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
|
BR112016029935A2
(pt)
|
2014-06-26 |
2017-10-31 |
Hoffmann La Roche |
?anticorpos anti-brdu, complexo, formulação farmacêutica e uso de anticorpo?
|
|
AU2015279321B2
(en)
|
2014-06-27 |
2021-03-04 |
Innate Pharma, S.A. |
Multispecific antigen binding proteins
|
|
JP6822849B2
(ja)
|
2014-06-27 |
2021-01-27 |
イナート・ファルマ・ソシエテ・アノニムＩｎｎａｔｅ Ｐｈａｒｍａ Ｐｈａｒｍａ Ｓ．Ａ． |
多重特異的ＮＫｐ４６結合タンパク質
|
|
TW201623329A
(zh)
|
2014-06-30 |
2016-07-01 |
亞佛瑞司股份有限公司 |
針對骨調素截斷變異體的疫苗及單株抗體暨其用途
|
|
EP3164492B1
(en)
|
2014-07-03 |
2019-10-23 |
F. Hoffmann-La Roche AG |
Polypeptide expression systems
|
|
AU2015286604B2
(en)
|
2014-07-10 |
2019-08-15 |
Hd Immune Gmbh |
Substances and methods for the use in prevention and/or treatment in Huntington's disease
|
|
ES2916923T3
(es)
|
2014-07-11 |
2022-07-06 |
Ventana Med Syst Inc |
Anticuerpos anti-PD-L1 y usos diagnósticos de los mismos
|
|
CN114621347A
(zh)
|
2014-07-11 |
2022-06-14 |
根马布股份公司 |
结合axl的抗体
|
|
BR112017000130A2
(pt)
|
2014-07-11 |
2018-01-09 |
Genentech Inc |
método para atenuar a toxicidade associada à inibição da via de notch e método de tratamento do câncer
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
SG11201700416TA
(en)
|
2014-07-21 |
2017-02-27 |
Novartis Ag |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
EP3193915A1
(en)
|
2014-07-21 |
2017-07-26 |
Novartis AG |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
US10174095B2
(en)
|
2014-07-21 |
2019-01-08 |
Novartis Ag |
Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor
|
|
US9777073B2
(en)
*
|
2014-07-21 |
2017-10-03 |
Wuhan Yzy Biopharma Co., Ltd. |
Construction and application of bispecific antibody EpCAM×CD3
|
|
WO2016016299A1
(en)
*
|
2014-07-29 |
2016-02-04 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
MY192917A
(en)
|
2014-07-30 |
2022-09-15 |
Ngm Biopharmaceuticals Inc |
Compositions and methods of use for treating metabolic disorders
|
|
EP3174546B1
(en)
|
2014-07-31 |
2019-10-30 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing t-cells
|
|
EP2982692A1
(en)
|
2014-08-04 |
2016-02-10 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
|
PE20211533A1
(es)
*
|
2014-08-04 |
2021-08-16 |
Hoffmann La Roche |
Moleculas biespecificas de unon a antigeno activadoras de celulas t
|
|
AU2015301460B2
(en)
|
2014-08-14 |
2021-04-08 |
Novartis Ag |
Treatment of cancer using GFR alpha-4 chimeric antigen receptor
|
|
DK3183268T3
(da)
|
2014-08-19 |
2020-05-11 |
Univ Pennsylvania |
Behandling af cancer ved anvendelse af en cd123-kimær antigenreceptor
|
|
KR102615681B1
(ko)
|
2014-08-28 |
2023-12-18 |
바이오아트라, 인코퍼레이티드 |
변형된 t 세포에 대한 조건부 활성 키메라 항원 수용체
|
|
US11111288B2
(en)
|
2014-08-28 |
2021-09-07 |
Bioatla, Inc. |
Conditionally active chimeric antigen receptors for modified t-cells
|
|
CA2959786A1
(en)
|
2014-09-03 |
2016-03-10 |
Bioatla, Llc |
Discovering and producing conditionally active biologic proteins in the same eukaryotic cell production hosts
|
|
PH12017500442B1
(en)
|
2014-09-09 |
2023-05-24 |
Janssen Biotech Inc |
Combination therapies with anti-cd38 antibodies
|
|
EP3191518B1
(en)
|
2014-09-12 |
2020-01-15 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
|
TW201625690A
(zh)
|
2014-09-12 |
2016-07-16 |
建南德克公司 |
抗－ｃｌｌ－１抗體及免疫結合物
|
|
KR102508173B1
(ko)
|
2014-09-12 |
2023-03-10 |
제넨테크, 인크. |
항-her2 항체 및 면역콘주게이트
|
|
TW201625688A
(zh)
|
2014-09-12 |
2016-07-16 |
建南德克公司 |
經半胱胺酸改造之抗體及接合物
|
|
AU2015318008B2
(en)
|
2014-09-15 |
2021-05-20 |
Amgen Inc. |
Bi-specific anti-CGRP receptor/PAC1 receptor antigen binding proteins and uses thereof
|
|
RU2727663C2
(ru)
|
2014-09-17 |
2020-07-22 |
Дженентек, Инк. |
Иммуноконъюгаты, содержащие антитела против her2 и пирролбензодиазепины
|
|
KR20210149228A
(ko)
|
2014-09-17 |
2021-12-08 |
노파르티스 아게 |
입양 면역요법을 위한 키메라 수용체에 의한 세포독성 세포의 표적화
|
|
EP3689910A3
(en)
|
2014-09-23 |
2020-12-02 |
F. Hoffmann-La Roche AG |
Method of using anti-cd79b immunoconjugates
|
|
US10905739B2
(en)
|
2014-09-24 |
2021-02-02 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles and formulations thereof
|
|
EP3197478A4
(en)
|
2014-09-24 |
2018-05-30 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles and uses thereof
|
|
MX2017003847A
(es)
|
2014-09-25 |
2017-12-15 |
Amgen Inc |
Proteinas biespecificas activables por proteasas.
|
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
|
WO2016055592A1
(en)
|
2014-10-09 |
2016-04-14 |
Engmab Ag |
Bispecific antibodies against cd3epsilon and ror1
|
|
EA201790834A1
(ru)
|
2014-10-14 |
2018-01-31 |
Новартис Аг |
Молекулы антител к pd-l1 и их применение
|
|
EP3207057A2
(en)
|
2014-10-16 |
2017-08-23 |
F. Hoffmann-La Roche AG |
Anti-alpha-synuclein antibodies and methods of use
|
|
EP4653013A2
(en)
|
2014-10-31 |
2025-11-26 |
The Trustees of the University of Pennsylvania |
Methods and compositions for modified t cells
|
|
PT3212233T
(pt)
|
2014-10-31 |
2020-07-16 |
Oncomed Pharm Inc |
Terapia combinada para o tratamento de doenças
|
|
US9920118B2
(en)
|
2014-10-31 |
2018-03-20 |
Ngm Biopharmaceuticals, Inc. |
Compositions and methods of use for treating metabolic disorders
|
|
CN106796235B
(zh)
|
2014-11-03 |
2021-01-29 |
豪夫迈·罗氏有限公司 |
用于检测t细胞免疫子集的测定法及其使用方法
|
|
SG11201703521UA
(en)
|
2014-11-03 |
2017-05-30 |
Genentech Inc |
Methods and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment
|
|
US11773166B2
(en)
|
2014-11-04 |
2023-10-03 |
Ichnos Sciences SA |
CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
|
|
WO2016073157A1
(en)
|
2014-11-06 |
2016-05-12 |
Genentech, Inc. |
Anti-ang2 antibodies and methods of use thereof
|
|
EP3842453A1
(en)
|
2014-11-06 |
2021-06-30 |
F. Hoffmann-La Roche AG |
Fc-region variants with modified fcrn- and protein a-binding properties
|
|
HRP20191766T1
(hr)
|
2014-11-06 |
2019-12-27 |
F. Hoffmann - La Roche Ag |
Varijante fc regije s modificiranim vezanjem na neonatalni fc receptor (fcrn) i postupci primjene
|
|
WO2016077369A1
(en)
|
2014-11-10 |
2016-05-19 |
Genentech, Inc. |
Animal model for nephropathy and agents for treating the same
|
|
EP3218403B1
(en)
|
2014-11-10 |
2020-05-13 |
F.Hoffmann-La Roche Ag |
Anti-interleukin-33 antibodies and uses thereof
|
|
DK3224275T3
(da)
|
2014-11-14 |
2020-05-04 |
Hoffmann La Roche |
Antigenbindende molekyler omfattende en TNF-familieligandtrimer
|
|
CN107250158B
(zh)
|
2014-11-19 |
2022-03-25 |
基因泰克公司 |
抗转铁蛋白受体/抗bace1多特异性抗体和使用方法
|
|
EP3221362B1
(en)
|
2014-11-19 |
2019-07-24 |
F.Hoffmann-La Roche Ag |
Anti-transferrin receptor antibodies and methods of use
|
|
EP3845565A3
(en)
|
2014-11-19 |
2021-09-08 |
Genentech, Inc. |
Antibodies against bace1 and use thereof for neural disease immunotherapy
|
|
MX2017006571A
(es)
|
2014-11-20 |
2017-09-29 |
Hoffmann La Roche |
Moleculas de union a antigeno biespecificas activadoras de celulas t.
|
|
EP3023437A1
(en)
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
|
HRP20201928T1
(hr)
|
2014-11-20 |
2021-02-05 |
F. Hoffmann - La Roche Ag |
Kombinirana terapija bispecifičnom antigen vezujućom molekulom koja aktivira t-stanice, za cd3 i folatni receptor 1 (folr1), i antagonistom vezivanja osi pd-1
|
|
LT3221357T
(lt)
|
2014-11-20 |
2020-08-25 |
F. Hoffmann-La Roche Ag |
Bendros lengvosios grandinės ir naudojimo būdai
|
|
CN107406512A
(zh)
|
2014-11-26 |
2017-11-28 |
Xencor公司 |
结合cd3和cd38的异二聚体抗体
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
RS62332B1
(sr)
|
2014-11-26 |
2021-10-29 |
Xencor Inc |
Heterodimerna antitela koja vezuju cd3 i cd20
|
|
WO2016082044A1
(en)
|
2014-11-27 |
2016-06-02 |
Zymeworks Inc. |
Methods of using bispecific antigen-binding constructs targeting her2
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
EP3227332B1
(en)
|
2014-12-03 |
2019-11-06 |
F.Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
IL307913A
(en)
|
2014-12-04 |
2023-12-01 |
Janssen Biotech Inc |
Anti-CD38 antibodies for the treatment of acute myeloid leukemia
|
|
CA2969730A1
(en)
|
2014-12-05 |
2016-06-09 |
Immunext, Inc. |
Identification of vsig8 as the putative vista receptor and its use thereof to produce vista/vsig8 modulators
|
|
RS59203B1
(sr)
|
2014-12-05 |
2019-10-31 |
Hoffmann La Roche |
Anti-cd79b antitela i postupci primene
|
|
CN107207591A
(zh)
|
2014-12-10 |
2017-09-26 |
豪夫迈·罗氏有限公司 |
血脑屏障受体抗体及使用方法
|
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
|
CN107002114A
(zh)
|
2014-12-18 |
2017-08-01 |
豪夫迈·罗氏有限公司 |
用于确定cdc引发抗体的测定试验和方法
|
|
JP6174782B2
(ja)
|
2014-12-19 |
2017-08-02 |
中外製薬株式会社 |
抗ｃ５抗体および使用方法
|
|
US10865253B2
(en)
|
2014-12-19 |
2020-12-15 |
Genmab A/S |
Rodent bispecific heterodimeric proteins
|
|
IL278014B2
(en)
|
2014-12-19 |
2023-10-01 |
Chugai Pharmaceutical Co Ltd |
Anti-myostatin antibodies, polypeptides containing variable FC regions and methods of use
|
|
US10428155B2
(en)
|
2014-12-22 |
2019-10-01 |
Xencor, Inc. |
Trispecific antibodies
|
|
CN110658340B
(zh)
*
|
2015-01-08 |
2023-10-31 |
苏州康宁杰瑞生物科技有限公司 |
具有共同轻链的双特异性抗体或抗体混合物
|
|
EP3247723A1
(en)
|
2015-01-22 |
2017-11-29 |
Chugai Seiyaku Kabushiki Kaisha |
A combination of two or more anti-c5 antibodies and methods of use
|
|
MA41375A
(fr)
|
2015-01-22 |
2017-11-28 |
Lilly Co Eli |
Anticorps igg bispécifiques et leurs procédés de préparation
|
|
US10828353B2
(en)
|
2015-01-31 |
2020-11-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for T cell delivery of therapeutic molecules
|
|
CN107108729A
(zh)
|
2015-02-05 |
2017-08-29 |
中外制药株式会社 |
包含离子浓度依赖性的抗原结合结构域的抗体，fc区变体，il‑8‑结合抗体，及其应用
|
|
US10859726B2
(en)
|
2015-03-03 |
2020-12-08 |
Schlumberger Technology Corporation |
Multi-mode acoustic tool and method
|
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
|
KR20170122216A
(ko)
|
2015-03-06 |
2017-11-03 |
제넨테크, 인크. |
초순수화 dsba 및 dsbc와 이를 제조하고 사용하는 방법
|
|
HK1247287A1
(zh)
|
2015-03-16 |
2018-09-21 |
F. Hoffmann-La Roche Ag |
检测和定量il-13的方法和在诊断和治疗th2相关疾病中的用途
|
|
US11111314B2
(en)
|
2015-03-19 |
2021-09-07 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals that select for light chain variable regions that bind antigen
|
|
WO2016146833A1
(en)
|
2015-03-19 |
2016-09-22 |
F. Hoffmann-La Roche Ag |
Biomarkers for nad(+)-diphthamide adp ribosyltransferase resistance
|
|
SG11201707750YA
(en)
|
2015-03-20 |
2017-10-30 |
Aileron Therapeutics Inc |
Peptidomimetic macrocycles and uses thereof
|
|
JP2018510637A
(ja)
|
2015-03-26 |
2018-04-19 |
アクセルロン ファーマ， インコーポレイテッド |
フォリスタチン関連融合タンパク質およびその使用
|
|
US11142587B2
(en)
|
2015-04-01 |
2021-10-12 |
Chugai Seiyaku Kabushiki Kaisha |
Method for producing polypeptide hetero-oligomer
|
|
MY186708A
(en)
|
2015-04-03 |
2021-08-11 |
Eureka Therapeutics Inc |
Constructs targeting afp peptide/mhc complexes and uses thereof
|
|
MA41919A
(fr)
|
2015-04-06 |
2018-02-13 |
Acceleron Pharma Inc |
Hétéromultimères alk4:actriib et leurs utilisations
|
|
WO2016164089A2
(en)
|
2015-04-06 |
2016-10-13 |
Acceleron Pharma Inc. |
Tgf-beta superfamily type i and type ii receptor heteromultimers and uses thereof
|
|
EP3280727B1
(en)
|
2015-04-06 |
2021-02-17 |
Acceleron Pharma Inc. |
Single-arm type i and type ii receptor fusion proteins and uses thereof
|
|
CA2981183A1
(en)
|
2015-04-07 |
2016-10-13 |
Greg Lazar |
Antigen binding complex having agonistic activity and methods of use
|
|
JP6999421B2
(ja)
|
2015-04-07 |
2022-02-04 |
アレクトル エルエルシー |
抗ソルチリン抗体及びその使用方法
|
|
HUE059218T2
(hu)
|
2015-04-08 |
2022-11-28 |
Novartis Ag |
CD20-terápiák, CD22-terápiák és kombinációs terápiák CD19 kiméra antigénreceptort (CAR-t) expresszáló sejttel
|
|
EP3280444B1
(en)
|
2015-04-10 |
2024-05-08 |
Adimab, LLC |
Methods for purifying heterodimeric multispecific antibodies from parental homodimeric antibody species
|
|
IL283764B2
(en)
|
2015-04-10 |
2024-01-01 |
Amgen Inc |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
|
WO2016166348A1
(en)
|
2015-04-17 |
2016-10-20 |
Elsalys Biotech |
Anti-tyro3 antibodies and uses thereof
|
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
CN115932273A
(zh)
|
2015-04-24 |
2023-04-07 |
豪夫迈·罗氏有限公司 |
鉴定包含结合多肽的细菌的方法
|
|
KR20240093813A
(ko)
|
2015-04-24 |
2024-06-24 |
제넨테크, 인크. |
다중특이적 항원-결합 단백질
|
|
CN107592812A
(zh)
|
2015-05-11 |
2018-01-16 |
豪夫迈·罗氏有限公司 |
治疗狼疮性肾炎的组合物和方法
|
|
AU2016262074A1
(en)
|
2015-05-12 |
2017-11-09 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
CN108136218B
(zh)
|
2015-05-20 |
2022-12-13 |
詹森生物科技公司 |
用于治疗轻链淀粉样变性及其它cd38阳性血液恶性肿瘤的抗cd38抗体
|
|
SG10201911335TA
(en)
|
2015-05-28 |
2020-01-30 |
Genentech Inc |
Cell-based assay for detecting anti-cd3 homodimers
|
|
CN107771182A
(zh)
|
2015-05-29 |
2018-03-06 |
豪夫迈·罗氏有限公司 |
人源化抗埃博拉病毒糖蛋白抗体和使用方法
|
|
EP3708681A1
(en)
|
2015-05-29 |
2020-09-16 |
F. Hoffmann-La Roche AG |
Therapeutic and diagnostic methods for cancer
|
|
JP2018516933A
(ja)
|
2015-06-02 |
2018-06-28 |
ジェネンテック， インコーポレイテッド |
抗ｉｌ−３４抗体を使用して神経学的疾患を治療するための組成物及び方法
|
|
CA3258972A1
(en)
|
2015-06-05 |
2025-04-17 |
Ac Immune Sa |
TAU ANTIBODIES AND METHODS OF USING THEM
|
|
CN107810011A
(zh)
|
2015-06-08 |
2018-03-16 |
豪夫迈·罗氏有限公司 |
使用抗ox40抗体治疗癌症的方法
|
|
US20170000885A1
(en)
|
2015-06-08 |
2017-01-05 |
Genentech, Inc. |
Methods of treating cancer using anti-ox40 antibodies and pd-1 axis binding antagonists
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
|
|
WO2016205176A1
(en)
|
2015-06-15 |
2016-12-22 |
Genentech, Inc. |
Antibodies and immunoconjugates
|
|
PE20240218A1
(es)
|
2015-06-16 |
2024-02-16 |
Genentech Inc |
Anticuerpos madurados por afinidad y humanizados para fcrh5
|
|
JP6996983B2
(ja)
|
2015-06-16 |
2022-02-21 |
ジェネンテック， インコーポレイテッド |
抗ｃｌｌ－１抗体及び使用方法
|
|
JP2018526972A
(ja)
|
2015-06-16 |
2018-09-20 |
ジェネンテック， インコーポレイテッド |
抗ｃｄ３抗体及び使用方法
|
|
LT3310812T
(lt)
|
2015-06-17 |
2025-10-10 |
|
Antikūnai prieš her2 ir jų naudojimo būdai
|
|
PE20181323A1
(es)
|
2015-06-22 |
2018-08-14 |
Janssen Biotech Inc |
Terapias de combinacion para enfermedades malignas hematologicas con anticuerpos anti-cd38 e inhibidores de survivina
|
|
AU2016284871B2
(en)
|
2015-06-23 |
2022-09-29 |
Innate Pharma |
Multispecific NK engager proteins
|
|
WO2016207245A1
(en)
|
2015-06-24 |
2016-12-29 |
F. Hoffmann-La Roche Ag |
Humanized anti-tau(ps422) antibodies and methods of use
|
|
CN107531788B
(zh)
|
2015-06-24 |
2022-06-21 |
豪夫迈·罗氏有限公司 |
对her2和血脑屏障受体特异性的三特异性抗体及使用方法
|
|
PT3313441T
(pt)
|
2015-06-24 |
2024-05-07 |
Janssen Biotech Inc |
Modulação imunitária e tratamento de tumores sólidos com anticorpos que se ligam especificamente a cd38
|
|
CN114805576A
(zh)
|
2015-06-24 |
2022-07-29 |
詹森药业有限公司 |
抗vista抗体和片段
|
|
WO2016207124A1
(en)
|
2015-06-25 |
2016-12-29 |
F. Hoffmann-La Roche Ag |
Cell based assay for determining antibody or ligand binding and function
|
|
CN108473573A
(zh)
|
2015-06-29 |
2018-08-31 |
豪夫迈·罗氏有限公司 |
Ii型抗cd20抗体用于器官移植中
|
|
EP3514174B1
(en)
|
2015-06-29 |
2021-03-31 |
Ventana Medical Systems, Inc. |
Materials and methods for performing histochemical assays for human pro-epiregulin and amphiregulin
|
|
WO2017004548A1
(en)
|
2015-07-01 |
2017-01-05 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles
|
|
WO2017005649A1
(en)
|
2015-07-09 |
2017-01-12 |
Genmab A/S |
Bispecific and multispecific antibodies and method for isolation of such
|
|
PT3319993T
(pt)
|
2015-07-10 |
2020-04-22 |
Genmab As |
Conjugados de anticorpo-fármaco específicos de axl para tratamento de cancro
|
|
JP7010811B2
(ja)
|
2015-07-10 |
2022-02-10 |
メルス ナムローゼ フェンノートシャップ |
ヒトｃｄ３結合抗体
|
|
BR112018000696A2
(pt)
|
2015-07-15 |
2018-09-18 |
Genmab As |
?anticorpo, métodos para reduzir e para aumentar a afinidade de ligação de um anticorpo que se liga ao cd3 humano, para tratar e para diagnosticar uma doença, para produzir um anticorpo e para detectar a presença de antígeno de cd3, construto de ácido nucleico, vetor de expressão, célula hospedeira, composição, e, kit?
|
|
ES2878188T3
(es)
|
2015-07-29 |
2021-11-18 |
Novartis Ag |
Terapias de combinación que comprenden moléculas de anticuerpos contra LAG-3
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
EP3316902A1
(en)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
ES2898958T3
(es)
|
2015-07-30 |
2022-03-09 |
Macrogenics Inc |
Moléculas de unión a PD-1 y LAG-3 y métodos de uso de las mismas
|
|
MY188405A
(en)
|
2015-08-05 |
2021-12-08 |
Janssen Biotech Inc |
Anti-cd154 antibodies and methods of using them
|
|
BR102016018074A2
(pt)
|
2015-08-07 |
2021-11-16 |
ALX Oncology Inc. |
Construção variante de sirp-alfa, seu método de preparação e seus usos, molécula de ácido nucleico, vetor, célula hospedeira, e composição farmacêutica
|
|
ES2881771T3
(es)
|
2015-08-07 |
2021-11-30 |
Alx Oncology Inc |
Constructos que tienen un dominio de SIRP-alfa o variante del mismo
|
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
|
WO2017027861A1
(en)
|
2015-08-13 |
2017-02-16 |
Amgen Inc. |
Charged depth filtration of antigen-binding proteins
|
|
CN107106682B
(zh)
|
2015-08-26 |
2021-05-25 |
比森医疗股份有限公司 |
多特异性抗体平台和相关方法
|
|
US11890301B2
(en)
|
2015-08-28 |
2024-02-06 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for cells expressing a chimeric intracellular signaling molecule
|
|
EP3340998B1
(en)
|
2015-08-28 |
2023-01-11 |
The Trustees of the University of Pennsylvania |
Methods and compositions for cells expressing a chimeric intracellular signaling molecule
|
|
AU2016319126A1
(en)
|
2015-09-10 |
2018-04-19 |
Affigen, Inc. |
Sequencing-directed selection of tumor theranostics
|
|
CN108368161A
(zh)
|
2015-09-10 |
2018-08-03 |
艾瑞朗医疗公司 |
作为mcl-1调节剂的拟肽大环化合物
|
|
EP3350216A1
(en)
|
2015-09-15 |
2018-07-25 |
Amgen Inc. |
Tetravalent bispecific and tetraspecific antigen binding proteins and uses thereof
|
|
CA2993423C
(en)
|
2015-09-18 |
2024-03-12 |
Chugai Seiyaku Kabushiki Kaisha |
Il-8-binding antibodies and uses thereof
|
|
JP6904947B2
(ja)
|
2015-09-22 |
2021-07-21 |
スプリング バイオサイエンス コーポレーション |
抗ｏｘ４０抗体及びその診断用途
|
|
RU2763916C2
(ru)
|
2015-09-23 |
2022-01-11 |
Дженентек, Инк. |
Оптимизированные варианты анти-vegf антител
|
|
ES2968074T3
(es)
|
2015-09-23 |
2024-05-07 |
Mereo Biopharma 5 Inc |
Anticuerpo bi-específico anti-VEGF/DLL4 para su uso en el tratamiento del cáncer de ovario resistente al platino
|
|
RU2757135C2
(ru)
|
2015-09-24 |
2021-10-11 |
АБВИТРО ЭлЭлСи |
Композиции антител к вич и способы их применения
|
|
CR20220186A
(es)
|
2015-09-25 |
2022-07-07 |
Genentech Inc |
ANTICUERPOS ANTI-TIGIT Y MÉTODOS DE USO (divisional 2018-0225)
|
|
AU2016332900C1
(en)
|
2015-09-29 |
2024-07-04 |
Amgen Inc. |
ASGR inhibitors
|
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
|
EP3150637A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Multispecific antibodies
|
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
|
WO2017055395A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xrob04 bispecific t cell activating antigen binding molecules
|
|
UA123826C2
(uk)
|
2015-10-02 |
2021-06-09 |
Ф. Хоффманн-Ля Рош Аг |
Антитіла до pd1 та способи їх застосування
|
|
AR106365A1
(es)
|
2015-10-02 |
2018-01-10 |
Hoffmann La Roche |
Moléculas biespecíficas de unión a antígeno activadoras de células t
|
|
EP3356409A2
(en)
|
2015-10-02 |
2018-08-08 |
H. Hoffnabb-La Roche Ag |
Bispecific t cell activating antigen binding molecules
|
|
EP3913000A1
(en)
|
2015-10-02 |
2021-11-24 |
F. Hoffmann-La Roche AG |
Bispecific anti-cd19xcd3 t cell activating antigen binding molecules
|
|
BR112018000835A2
(pt)
|
2015-10-02 |
2018-09-11 |
Hoffmann La Roche |
molécula, um ou mais polinucleotídeos, um ou mais vetores, célula, método de produção da molécula, composição, uso da molécula, método de tratamento de uma doença e método para induzir a lise de uma célula-alvo
|
|
CN108139394B
(zh)
|
2015-10-02 |
2020-10-30 |
豪夫迈·罗氏有限公司 |
用于确定同时结合的基于细胞的fret测定法
|
|
IL257110B
(en)
|
2015-10-02 |
2022-09-01 |
Hoffmann La Roche |
Bispecific antibodies specific against pd1 and tim3
|
|
JP7239320B2
(ja)
*
|
2015-10-02 |
2023-03-14 |
エフ． ホフマン－ラ ロシュ アーゲー |
多重特異性抗体
|
|
WO2017055385A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xgd2 bispecific t cell activating antigen binding molecules
|
|
RU2761115C1
(ru)
|
2015-10-02 |
2021-12-06 |
Ф. Хоффманн-Ля Рош Аг |
Биспецифические антитела, специфические в отношении костимуляторного tnf-рецептора
|
|
WO2017055393A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xtim-3 bispecific t cell activating antigen binding molecules
|
|
WO2017055392A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xcd44v6 bispecific t cell activating antigen binding molecules
|
|
AU2016334623A1
(en)
|
2015-10-07 |
2018-02-15 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies with tetravalency for a costimulatory TNF receptor
|
|
PL3359576T3
(pl)
|
2015-10-08 |
2025-04-14 |
Zymeworks Bc Inc. |
Konstrukty polipeptydowe wiążące antygen zawierające łańcuchy lekkie kappa i lambda oraz ich zastosowania
|
|
KR101851380B1
(ko)
|
2015-10-12 |
2018-04-23 |
아주대학교산학협력단 |
효모접합을 이용한 항체 ch3 도메인 이종이중체 돌연변이쌍 제조 방법 및 이에 의하여 제조된 ch3 돌연변이체 쌍
|
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
|
MA45326A
(fr)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
|
|
CA3002957A1
(en)
|
2015-10-23 |
2017-04-27 |
Koninklijke Nederlandse Akademie Van Wetenschappen |
Binding molecules that inhibit cancer growth
|
|
WO2017072210A1
(en)
|
2015-10-29 |
2017-05-04 |
F. Hoffmann-La Roche Ag |
Anti-variant fc-region antibodies and methods of use
|
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
|
EP3368578B1
(en)
|
2015-10-30 |
2021-03-17 |
H. Hoffnabb-La Roche Ag |
Anti-htra1 antibodies and methods of use thereof
|
|
CN108289951A
(zh)
|
2015-10-30 |
2018-07-17 |
豪夫迈·罗氏有限公司 |
抗-因子d抗体和缀合物
|
|
HUE053366T2
(hu)
|
2015-11-03 |
2021-06-28 |
Janssen Biotech Inc |
Szubkután anti-CD38-ellenanyag-készítmények és alkalmazásuk
|
|
JP6998869B2
(ja)
|
2015-11-08 |
2022-02-04 |
ジェネンテック， インコーポレイテッド |
多重特異性抗体のスクリーニング方法
|
|
US11649293B2
(en)
|
2015-11-18 |
2023-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Method for enhancing humoral immune response
|
|
WO2017086367A1
(ja)
|
2015-11-18 |
2017-05-26 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するｔ細胞リダイレクト抗原結合分子を用いた併用療法
|
|
WO2017093447A1
(en)
|
2015-12-01 |
2017-06-08 |
Genmab B.V. |
Anti-death receptor antibodies and methods of use thereof
|
|
US11623957B2
(en)
|
2015-12-07 |
2023-04-11 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and PSMA
|
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
|
ES2901794T3
(es)
|
2015-12-09 |
2022-03-23 |
Hoffmann La Roche |
Anticuerpo anti-CD20 de tipo II para reducir la formación de anticuerpos antifármaco
|
|
MA44082A
(fr)
|
2015-12-14 |
2018-10-24 |
Macrogenics Inc |
Molécules bispécifiques présentant une immunoréactivité par rapport à pd-1 et à ctla-4 et leurs procédés d'utilisation
|
|
CR20180365A
(es)
|
2015-12-16 |
2018-09-28 |
Amgen Inc |
PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS
|
|
CN106883297B
(zh)
|
2015-12-16 |
2019-12-13 |
苏州康宁杰瑞生物科技有限公司 |
基于ch3结构域的异二聚体分子、其制备方法及用途
|
|
WO2017106656A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
|
CN108697794A
(zh)
|
2015-12-17 |
2018-10-23 |
诺华股份有限公司 |
C-met抑制剂和抗pd-1抗体分子的组合及其用途
|
|
MA44072A
(fr)
|
2015-12-17 |
2018-10-24 |
Janssen Biotech Inc |
Anticorps se liant spécifiquement à hla-dr et leurs utilisations
|
|
ES2969440T3
(es)
|
2015-12-18 |
2024-05-20 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos anti-C5 y métodos de uso
|
|
KR102709693B1
(ko)
|
2015-12-18 |
2024-09-24 |
추가이 세이야쿠 가부시키가이샤 |
항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
|
|
EP4643874A2
(en)
|
2015-12-22 |
2025-11-05 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
|
WO2017110980A1
(ja)
|
2015-12-25 |
2017-06-29 |
中外製薬株式会社 |
増強された活性を有する抗体及びその改変方法
|
|
EP3397646A1
(en)
|
2015-12-28 |
2018-11-07 |
Massachusetts Institute of Technology |
Bispecific antibodies having constant region mutations and uses therefor
|
|
US11649262B2
(en)
|
2015-12-28 |
2023-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Method for promoting efficiency of purification of Fc region-containing polypeptide
|
|
KR20180097615A
(ko)
|
2016-01-08 |
2018-08-31 |
에프. 호프만-라 로슈 아게 |
Pd-1 축 결합 길항물질 및 항-cea/항-cd3 이중특이성 항체를 사용하는 cea-양성 암의 치료 방법
|
|
CA3011739A1
(en)
|
2016-01-20 |
2017-07-27 |
Genentech, Inc. |
High dose treatments for alzheimer's disease
|
|
EP3405492B1
(en)
|
2016-01-21 |
2020-10-21 |
Novartis AG |
Multispecific molecules targeting cll-1
|
|
BR112018016461A2
(pt)
|
2016-02-12 |
2019-10-01 |
Janssen Pharmaceutica Nv |
anticorpos e fragmentos anti-vista, usos dos mesmos e métodos de identificação dos mesmos
|
|
JP6821693B2
(ja)
|
2016-02-29 |
2021-01-27 |
ジェネンテック， インコーポレイテッド |
がんのための治療方法及び診断方法
|
|
ES2972740T3
(es)
|
2016-03-02 |
2024-06-14 |
Momenta Pharmaceuticals Inc |
Procedimientos relacionados con construcciones de Fc modificadas genéticamente
|
|
US20200281973A1
(en)
|
2016-03-04 |
2020-09-10 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
|
MX2018010988A
(es)
|
2016-03-14 |
2019-01-21 |
Chugai Pharmaceutical Co Ltd |
Farmaco terapeutico que induce lesion celular para usarse en terapia de cancer.
|
|
WO2017165464A1
(en)
|
2016-03-21 |
2017-09-28 |
Elstar Therapeutics, Inc. |
Multispecific and multifunctional molecules and uses thereof
|
|
EP3433280B1
(en)
|
2016-03-22 |
2023-04-19 |
F. Hoffmann-La Roche AG |
Protease-activated t cell bispecific molecules
|
|
RS64266B1
(sr)
|
2016-03-22 |
2023-07-31 |
Hoffmann La Roche |
Bispecifični molekul koji aktivira t ćeliju koji se aktivira proteazom
|
|
WO2017165683A1
(en)
|
2016-03-23 |
2017-09-28 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
|
WO2017165734A1
(en)
|
2016-03-25 |
2017-09-28 |
Genentech, Inc. |
Multiplexed total antibody and antibody-conjugated drug quantification assay
|
|
CA3016035A1
(en)
|
2016-03-31 |
2017-10-05 |
Ngm Biopharmaceuticals, Inc. |
Binding proteins and methods of use thereof
|
|
WO2017177013A1
(en)
|
2016-04-06 |
2017-10-12 |
Acceleron Pharma Inc. |
Alk7 antagonists and uses thereof
|
|
US20170319688A1
(en)
|
2016-04-14 |
2017-11-09 |
Genentech, Inc. |
Anti-rspo3 antibodies and methods of use
|
|
SI3443096T1
(sl)
|
2016-04-15 |
2023-07-31 |
Novartis Ag |
Sestavki in postopki za selektivno izražanje himerni antigenskih receptorjev
|
|
WO2017180842A1
(en)
|
2016-04-15 |
2017-10-19 |
Bioatla, Llc |
Anti-axl antibodies, antibody fragments and their immunoconjugates and uses thereof
|
|
CA3020848A1
(en)
|
2016-04-15 |
2017-10-19 |
Janssen Pharmaceuticals, Inc. |
Anti-human vista antibodies and use thereof
|
|
KR20190003957A
(ko)
|
2016-04-15 |
2019-01-10 |
제넨테크, 인크. |
암 모니터링 및 치료 방법
|
|
WO2017181111A2
(en)
|
2016-04-15 |
2017-10-19 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
|
WO2017184831A1
(en)
|
2016-04-20 |
2017-10-26 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for making antibodies based on use of an expression-enhancing locus
|
|
AR109451A1
(es)
|
2016-04-20 |
2018-12-12 |
Regeneron Pharma |
Composiciones y métodos para preparar anticuerpos basados en el uso de loci mejoradores de expresión
|
|
MX2018012648A
(es)
|
2016-04-28 |
2019-01-30 |
Chugai Pharmaceutical Co Ltd |
Preparaciones que contienen anticuerpos.
|
|
EP3889175A1
(en)
|
2016-05-02 |
2021-10-06 |
F. Hoffmann-La Roche AG |
The contorsbody - a single chain target binder
|
|
KR20240115933A
(ko)
|
2016-05-04 |
2024-07-26 |
암젠 인크 |
T-조절 세포의 증식을 위한 인터류킨-2 뮤테인
|
|
EP3243836A1
(en)
|
2016-05-11 |
2017-11-15 |
F. Hoffmann-La Roche AG |
C-terminally fused tnf family ligand trimer-containing antigen binding molecules
|
|
CN109071652B
(zh)
|
2016-05-11 |
2022-09-23 |
豪夫迈·罗氏有限公司 |
包含tnf家族配体三聚体和生腱蛋白结合模块的抗原结合分子
|
|
CN109071640B
(zh)
|
2016-05-11 |
2022-10-18 |
豪夫迈·罗氏有限公司 |
经修饰抗生腱蛋白抗体及使用方法
|
|
LT3455261T
(lt)
|
2016-05-13 |
2022-11-10 |
Bioatla, Inc. |
Antikūnai prieš ror2, antikūnų fragmentai, jų imunokonjugatai ir panaudojimas
|
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
|
WO2017201036A1
(en)
|
2016-05-17 |
2017-11-23 |
Genentech, Inc. |
Stromal gene signatures for diagnosis and use in immunotherapy
|
|
JP2019522633A
(ja)
|
2016-05-20 |
2019-08-15 |
ジェネンテック， インコーポレイテッド |
Ｐｒｏｔａｃ抗体コンジュゲート及び使用方法
|
|
NZ749292A
(en)
|
2016-05-23 |
2025-08-29 |
Momenta Pharmaceuticals Inc |
Compositions and methods related to engineered fc constructs
|
|
CN109475627B
(zh)
*
|
2016-05-26 |
2023-01-06 |
齐鲁普吉湾生物治疗公司 |
抗体混合物
|
|
EP3465221B1
(en)
|
2016-05-27 |
2020-07-22 |
H. Hoffnabb-La Roche Ag |
Bioanalytical method for the characterization of site-specific antibody-drug conjugates
|
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
|
WO2017210617A2
(en)
|
2016-06-02 |
2017-12-07 |
Porter, David, L. |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
AU2018276419A1
(en)
|
2016-06-02 |
2019-10-17 |
F. Hoffmann-La Roche Ag |
Type II anti-CD20 antibody and anti-CD20/CD3 bispecific antibody for treatment of cancer
|
|
JP7043425B2
(ja)
|
2016-06-06 |
2022-03-29 |
ジェネンテック， インコーポレイテッド |
シルベストロール抗体－薬物コンジュゲート及び使用方法
|
|
IL263542B2
(en)
|
2016-06-14 |
2024-10-01 |
Xencor Inc |
Bispecific antibodies inhibit immunological checkpoint
|
|
KR102680483B1
(ko)
|
2016-06-17 |
2024-07-01 |
추가이 세이야쿠 가부시키가이샤 |
항-마이오스타틴 항체 및 사용 방법
|
|
EP4549463A3
(en)
|
2016-06-17 |
2025-07-30 |
F. Hoffmann-La Roche AG |
Purification of multispecific antibodies
|
|
CN116143918A
(zh)
|
2016-06-24 |
2023-05-23 |
豪夫迈·罗氏有限公司 |
抗聚泛素多特异性抗体
|
|
EP3474895A1
(en)
|
2016-06-28 |
2019-05-01 |
UMC Utrecht Holding B.V. |
TREATMENT OF IgE-MEDIATED DISEASES WITH ANTIBODIES THAT SPECIFICALLY BIND CD38
|
|
CN116063545A
(zh)
|
2016-06-28 |
2023-05-05 |
Xencor股份有限公司 |
结合生长抑素受体2的异源二聚抗体
|
|
CN119120423A
(zh)
|
2016-07-01 |
2024-12-13 |
分解治疗有限责任公司 |
优化的二核酸酶融合体和方法
|
|
EP3478717B1
(en)
|
2016-07-04 |
2022-01-05 |
F. Hoffmann-La Roche AG |
Novel antibody format
|
|
MA45672A
(fr)
|
2016-07-14 |
2019-05-22 |
Biontech Ag |
Anticorps multispécifiques dirigés contre cd40 et cd137
|
|
US20190336504A1
(en)
|
2016-07-15 |
2019-11-07 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
|
RS62011B1
(sr)
|
2016-07-15 |
2021-07-30 |
Acceleron Pharma Inc |
Kompozicije koje sadrže polipeptide actriia za upotrebu u lečenju plućne hipertenzije
|
|
CN109476763B
(zh)
*
|
2016-07-19 |
2023-11-07 |
伊班绰斯有限责任公司 |
双特异性蛋白质及其制备方法
|
|
WO2018014260A1
(en)
|
2016-07-20 |
2018-01-25 |
Nanjing Legend Biotech Co., Ltd. |
Multispecific antigen binding proteins and methods of use thereof
|
|
WO2018018011A2
(en)
|
2016-07-22 |
2018-01-25 |
Amgen Inc. |
Methods of purifying fc-containing proteins
|
|
RS65735B1
(sr)
|
2016-07-27 |
2024-08-30 |
Acceleron Pharma Inc |
Kompozicije za upotrebu u lečenju mijelofibroze
|
|
CN110214150A
(zh)
|
2016-07-28 |
2019-09-06 |
诺华股份有限公司 |
嵌合抗原受体和pd-1抑制剂的组合疗法
|
|
AU2017303205B2
(en)
|
2016-07-29 |
2024-08-01 |
Chugai Seiyaku Kabushiki Kaisha |
Bispecific antibody exhibiting increased alternative FVIII-cofactor-function activity
|
|
JP2019527696A
(ja)
|
2016-08-01 |
2019-10-03 |
ノバルティス アーゲー |
プロｍ２マクロファージ分子の阻害剤と組み合わせてキメラ抗原受容体を用いる癌の処置
|
|
WO2018026942A1
(en)
*
|
2016-08-02 |
2018-02-08 |
Merrimack Pharmaceuticals, Inc. |
Heteromeric polypeptides
|
|
TWI831965B
(zh)
|
2016-08-05 |
2024-02-11 |
日商中外製藥股份有限公司 |
Il-8相關疾病之治療用或預防用組成物
|
|
US11046776B2
(en)
|
2016-08-05 |
2021-06-29 |
Genentech, Inc. |
Multivalent and multiepitopic antibodies having agonistic activity and methods of use
|
|
EP3511340B1
(en)
|
2016-08-10 |
2024-10-02 |
Ajou University Industry-Academic Cooperation Foundation |
Heterodimeric fc-fused cytokine and pharmaceutical composition comprising the same
|
|
JP7093767B2
(ja)
|
2016-08-11 |
2022-06-30 |
ジェネンテック， インコーポレイテッド |
ピロロベンゾジアゼピンプロドラッグ及びその抗体コンジュゲート
|
|
US11793180B2
(en)
|
2016-08-22 |
2023-10-24 |
Chugai Seiyaku Kabushiki Kaisha |
Gene-modified mouse expressing human GPC3 polypeptide
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
SG10201607778XA
(en)
|
2016-09-16 |
2018-04-27 |
Chugai Pharmaceutical Co Ltd |
Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
|
|
CN116731197A
(zh)
|
2016-09-19 |
2023-09-12 |
豪夫迈·罗氏有限公司 |
基于补体因子的亲和层析
|
|
NZ790629A
(en)
|
2016-09-23 |
2025-11-28 |
Genentech Inc |
Uses of il-13 antagonists for treating atopic dermatitis
|
|
EP3504234A4
(en)
|
2016-09-29 |
2020-12-02 |
Beijing Hanmi Pharmaceutical Co., Ltd. |
CONSTRUCTIONS OF HETERODIMERIC IMMUNOGLOBULINS AND THEIR PREPARATION PROCESSES
|
|
WO2018060035A1
(en)
|
2016-09-30 |
2018-04-05 |
F. Hoffmann-La Roche Ag |
Spr-based dual-binding assay for the functional analysis of multispecific molecules
|
|
JP7022123B2
(ja)
|
2016-09-30 |
2022-02-17 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
Ｃｄ３に対する二重特異性抗体
|
|
CN110036025B
(zh)
*
|
2016-10-05 |
2024-03-22 |
阿塞勒隆制药公司 |
变体ActRIIB蛋白及其用途
|
|
AU2017340504A1
(en)
|
2016-10-05 |
2019-04-11 |
Acceleron Pharma, Inc. |
Compositions and method for treating kidney disease
|
|
KR20190075078A
(ko)
|
2016-10-05 |
2019-06-28 |
악셀레론 파마 인코포레이티드 |
ALK4:ActRIIB 이형다량체 및 이의 용도
|
|
WO2018065501A1
(en)
|
2016-10-05 |
2018-04-12 |
F. Hoffmann-La Roche Ag |
Methods for preparing antibody drug conjugates
|
|
CN110418851A
(zh)
|
2016-10-06 |
2019-11-05 |
基因泰克公司 |
癌症的治疗和诊断方法
|
|
CA3039646A1
(en)
|
2016-10-07 |
2018-04-12 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
|
WO2018068201A1
(en)
|
2016-10-11 |
2018-04-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against ctla-4
|
|
MA46534A
(fr)
|
2016-10-14 |
2019-08-21 |
Xencor Inc |
Protéines de fusion fc hétérodimères il15/il15r
|
|
CN118359705A
(zh)
|
2016-10-19 |
2024-07-19 |
英温拉公司 |
抗体构建体
|
|
JP2019535250A
(ja)
|
2016-10-29 |
2019-12-12 |
ジェネンテック， インコーポレイテッド |
抗ｍｉｃ抗体及び使用方法
|
|
US20190276549A1
(en)
|
2016-11-01 |
2019-09-12 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
|
EP3538137A2
(en)
|
2016-11-08 |
2019-09-18 |
Qilu Puget Sound Biotherapeutics Corporation |
Anti-pd1 and anti-ctla4 antibodies
|
|
WO2018089715A1
(en)
|
2016-11-10 |
2018-05-17 |
Keros Therapeutics, Inc. |
Activin receptor type iia variants and methods of use thereof
|
|
MA46753A
(fr)
|
2016-11-14 |
2019-09-18 |
Amgen Inc |
Protéines de liaison à l'antigène bispécifiques ou biparatopiques et utilisations de celles-ci
|
|
US11466094B2
(en)
|
2016-11-15 |
2022-10-11 |
Genentech, Inc. |
Dosing for treatment with anti-CD20/anti-CD3 bispecific antibodies
|
|
SG10201913260VA
(en)
|
2016-11-18 |
2020-03-30 |
Beijing Hanmi Pharmaceutical Co Ltd |
Anti-pd-1/anti-her2 natural antibody structural heterodimeric bispecific antibody and method of preparing the same
|
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
|
JOP20190100A1
(ar)
|
2016-11-19 |
2019-05-01 |
Potenza Therapeutics Inc |
بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها
|
|
AU2017363309A1
(en)
|
2016-11-23 |
2019-07-11 |
Bioverativ Therapeutics Inc. |
Mono- and bispecific antibodies binding to coagulation factor IX and coagulation factor X
|
|
JP2020511937A
(ja)
|
2016-12-07 |
2020-04-23 |
ジェネンテック， インコーポレイテッド |
抗ｔａｕ抗体及び使用方法
|
|
WO2018106781A1
(en)
|
2016-12-07 |
2018-06-14 |
Genentech, Inc |
Anti-tau antibodies and methods of use
|
|
WO2018108759A1
(en)
|
2016-12-13 |
2018-06-21 |
F. Hoffmann-La Roche Ag |
Method to determine the presence of a target antigen in a tumor sample
|
|
EP3554542A1
(en)
|
2016-12-19 |
2019-10-23 |
H. Hoffnabb-La Roche Ag |
Combination therapy with targeted 4-1bb (cd137) agonists
|
|
WO2018114748A1
(en)
|
2016-12-20 |
2018-06-28 |
F. Hoffmann-La Roche Ag |
Combination therapy of anti-cd20/anti-cd3 bispecific antibodies and 4-1bb (cd137) agonists
|
|
CN110100007B
(zh)
|
2016-12-21 |
2024-05-28 |
豪夫迈·罗氏有限公司 |
用于体外糖工程化抗体的酶的再使用
|
|
WO2018114772A1
(en)
|
2016-12-21 |
2018-06-28 |
F. Hoffmann-La Roche Ag |
Assay for determining antibody or ligand binding and function
|
|
AU2017381657B2
(en)
|
2016-12-21 |
2020-07-23 |
F. Hoffmann-La Roche Ag |
Method for in vitro glycoengineering of antibodies
|
|
AU2017384276B9
(en)
|
2016-12-21 |
2020-11-26 |
F. Hoffmann-La Roche Ag |
In vitro glycoengineering of antibodies
|
|
EP3360898A1
(en)
|
2017-02-14 |
2018-08-15 |
Boehringer Ingelheim International GmbH |
Bispecific anti-tnf-related apoptosis-inducing ligand receptor 2 and anti-cadherin 17 binding molecules for the treatment of cancer
|
|
US20190322767A1
(en)
|
2016-12-23 |
2019-10-24 |
Innate Pharma |
Heterodimeric antigen binding proteins
|
|
MX2019007795A
(es)
|
2017-01-03 |
2019-08-16 |
Hoffmann La Roche |
Moleculas de union a antigeno biespecificas que comprenden el clon 20h4.9 anti-4-1bb.
|
|
CN110650748B
(zh)
|
2017-01-06 |
2024-01-02 |
动量制药公司 |
与经工程改造的Fc构建体相关的组合物和方法
|
|
EP3568468A4
(en)
|
2017-01-12 |
2020-12-30 |
Eureka Therapeutics, Inc. |
RECOMBINATION PRODUCTS TARGETING PEPTIDE HISTONE H3 / MHC COMPLEXES AND THEIR USES
|
|
EP3574005B1
(en)
|
2017-01-26 |
2021-12-15 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
WO2018144784A1
(en)
|
2017-02-01 |
2018-08-09 |
Smet Pharmaceutical Inc. |
MONOMERIC HUMAN IgG1 Fc AND BISPECIFIC ANTIBODIES
|
|
WO2018147245A1
(ja)
|
2017-02-07 |
2018-08-16 |
第一三共株式会社 |
抗ｇｐｒｃ５ｄ抗体及び該抗体を含む分子
|
|
CA3221995C
(en)
|
2017-02-08 |
2024-05-28 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
|
|
US20190375838A1
(en)
*
|
2017-02-10 |
2019-12-12 |
Dragonfly Therapeutics, Inc. |
Proteins binding bcma, nkg2d and cd16
|
|
AU2018217816A1
(en)
|
2017-02-10 |
2019-08-15 |
Genentech, Inc. |
Anti-tryptase antibodies, compositions thereof, and uses thereof
|
|
CA3053222A1
(en)
|
2017-02-10 |
2018-08-16 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
|
WO2018151820A1
(en)
|
2017-02-16 |
2018-08-23 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
|
SG11201907646YA
(en)
|
2017-02-20 |
2019-09-27 |
Dragonfly Therapeutics Inc |
Proteins binding her2, nkg2d and cd16
|
|
US12054544B2
(en)
|
2017-02-24 |
2024-08-06 |
Chugai Seiyaku Kabushiki Kaisha |
Compositions comprising antigen-binding molecules
|
|
AU2018228873A1
(en)
|
2017-03-01 |
2019-08-29 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
EP3589650A1
(en)
|
2017-03-02 |
2020-01-08 |
Novartis AG |
Engineered heterodimeric proteins
|
|
LT3592769T
(lt)
|
2017-03-09 |
2024-08-26 |
Genmab A/S |
Antikūnai, atpažįstantys pd-l1
|
|
CN110402253B
(zh)
|
2017-03-10 |
2024-01-05 |
豪夫迈·罗氏有限公司 |
用于生产多特异性抗体的方法
|
|
AR111190A1
(es)
|
2017-03-22 |
2019-06-12 |
Genentech Inc |
Composiciones en hidrogel de prodrogas entrecruzadas de ácido hialurónico y métodos relacionados
|
|
AU2018237359B2
(en)
|
2017-03-22 |
2024-06-27 |
Genentech, Inc. |
Optimized antibody compositions for treatment of ocular disorders
|
|
SG11201908326YA
(en)
|
2017-03-28 |
2019-10-30 |
Genentech Inc |
Methods of treating neurodegenerative diseases
|
|
WO2018178055A1
(en)
|
2017-03-29 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Bispecific antigen binding molecule for a costimulatory tnf receptor
|
|
JP7205995B2
(ja)
|
2017-03-29 |
2023-01-17 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
共刺激性ｔｎｆ受容体に対する二重特異性抗原結合分子
|
|
EP3600413A1
(en)
|
2017-03-31 |
2020-02-05 |
Merus N.V. |
Erbb-2 and erbb3 binding bispecific antibodies for use in the treatment f cells that have an nrg1 fusion gene
|
|
WO2018178396A1
(en)
|
2017-03-31 |
2018-10-04 |
Genmab Holding B.V. |
Bispecific anti-cd37 antibodies, monoclonal anti-cd37 antibodies and methods of use thereof
|
|
SG11201909156RA
(en)
|
2017-04-01 |
2019-10-30 |
Beijing hanmi pharm co ltd |
Anti-pd-l1/anti-pd-1 natural antibody structure-like heterodimeric bispecific antibody and preparation thereof
|
|
EP3606960A1
(en)
|
2017-04-03 |
2020-02-12 |
Oncologie, Inc. |
Methods for treating cancer using ps-targeting antibodies with immuno-oncology agents
|
|
WO2018184965A1
(en)
|
2017-04-03 |
2018-10-11 |
F. Hoffmann-La Roche Ag |
Immunoconjugates of il-2 with an anti-pd-1 and tim-3 bispecific antibody
|
|
KR102461885B1
(ko)
|
2017-04-03 |
2022-11-03 |
에프. 호프만-라 로슈 아게 |
항-pd-1 항체와 돌연변이 il-2 또는 il-15의 면역접합체
|
|
AU2018247767B2
(en)
|
2017-04-03 |
2025-01-30 |
F. Hoffmann-La Roche Ag |
Antibodies binding to STEAP-1
|
|
MX2019011907A
(es)
|
2017-04-04 |
2020-01-09 |
Hoffmann La Roche |
Nuevas moleculas de union a antigeno biespecificas capaces de unirse especificamente a cd40 y a fap.
|
|
EP4516809A3
(en)
|
2017-04-05 |
2025-09-03 |
F. Hoffmann-La Roche AG |
Bispecific antibodies specifically binding to pd1 and lag3
|
|
IL268620B2
(en)
|
2017-04-05 |
2024-04-01 |
Hoffmann La Roche |
Antibodies against LAG3 pharmaceutical formulations containing them, and their uses for cancer treatment
|
|
BR112019020940A2
(pt)
|
2017-04-11 |
2020-05-05 |
Inhibrx, Inc. |
construções polipeptídicas multipecíficas que têm ligação a cd3 restrita e métodos de usar as mesmas
|
|
BR112019021411A2
(pt)
|
2017-04-13 |
2020-05-05 |
Hoffmann La Roche |
métodos para tratar ou retardar a progressão do câncer e para melhorar a função, usos de um imunoconjugado, de um agonista, de um antagonista, composições, kit e invenção
|
|
JOP20190248A1
(ar)
|
2017-04-21 |
2019-10-20 |
Amgen Inc |
بروتينات ربط مولد ضد trem2 واستخداماته
|
|
MX2019012419A
(es)
|
2017-04-21 |
2019-12-05 |
Genentech Inc |
Uso de antagonistas de klk5 para el tratamiento de una enfermedad.
|
|
SG11201909728XA
(en)
|
2017-04-26 |
2019-11-28 |
Eureka Therapeutics Inc |
Constructs specifically recognizing glypican 3 and uses thereof
|
|
US20200179511A1
(en)
|
2017-04-28 |
2020-06-11 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
KR102744809B1
(ko)
|
2017-05-17 |
2024-12-23 |
메뤼스 엔.페. |
유방암 치료를 위한 ErbB-2/ErbB-3 이중특이적 항체와 내분비 치료의 조합
|
|
EP3630836A1
(en)
|
2017-05-31 |
2020-04-08 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
|
JP2020522543A
(ja)
|
2017-06-07 |
2020-07-30 |
ゲンマブ ビー．ブイ． |
変異ＩｇＧ六量体に基づく治療用抗体
|
|
UY37758A
(es)
|
2017-06-12 |
2019-01-31 |
Novartis Ag |
Método de fabricación de anticuerpos biespecíficos, anticuerpos biespecíficos y uso terapéutico de dichos anticuerpos
|
|
CN110785187B
(zh)
|
2017-06-22 |
2024-04-05 |
诺华股份有限公司 |
针对cd73的抗体分子及其用途
|
|
US20200223924A1
(en)
|
2017-06-27 |
2020-07-16 |
Novartis Ag |
Dosage regimens for anti-tim-3 antibodies and uses thereof
|
|
WO2019006472A1
(en)
|
2017-06-30 |
2019-01-03 |
Xencor, Inc. |
TARGETED HETETRODIMERIC FUSION PROTEINS CONTAINING IL-15 / IL-15RA AND ANTIGEN-BINDING DOMAINS
|
|
AR112603A1
(es)
|
2017-07-10 |
2019-11-20 |
Lilly Co Eli |
Anticuerpos biespecíficos inhibidores de punto de control
|
|
MX2020000342A
(es)
|
2017-07-11 |
2020-08-17 |
Compass Therapeutics Llc |
Anticuerpos agonistas que se unen a cd137 humano y sus usos.
|
|
IL319798A
(en)
|
2017-07-20 |
2025-05-01 |
Novartis Ag |
ANTI-LAG-3 Antibody Dosage Regimens and Their Uses
|
|
MX2020000604A
(es)
|
2017-07-21 |
2020-09-10 |
Genentech Inc |
Métodos terapéuticos y de diagnóstico para el cáncer.
|
|
AU2018308364C1
(en)
|
2017-07-26 |
2023-02-16 |
Forty Seven, LLC |
Anti-SIRP-alpha antibodies and related methods
|
|
CN111406067B
(zh)
|
2017-08-04 |
2022-11-08 |
健玛保 |
与pd-l1和cd137结合的结合剂及其用途
|
|
PL3665198T3
(pl)
|
2017-08-09 |
2025-06-09 |
Merus N.V. |
Przeciwciała wiążące egfr i cmet
|
|
MX2020000903A
(es)
|
2017-08-11 |
2020-07-22 |
Genentech Inc |
Anticuerpos anti-cd8 y usos de los mismos.
|
|
EP3672986A1
(en)
|
2017-08-22 |
2020-07-01 |
Sanabio, LLC |
Soluble interferon receptors and uses thereof
|
|
CN111108202B
(zh)
|
2017-09-29 |
2024-10-22 |
中外制药株式会社 |
具有凝血因子viii(fviii)辅因子功能替代活性的多特异性抗原结合分子及含有所述分子作为活性成分的药物制剂
|
|
CA3078974A1
(en)
|
2017-10-12 |
2019-04-18 |
Immunowake Inc. |
Vegfr-antibody light chain fusion protein
|
|
JP7450535B2
(ja)
*
|
2017-10-20 |
2024-03-15 |
エフ． ホフマン－ラ ロシュ アーゲー |
単一特異性抗体から多重特異性抗体を生成させるための方法
|
|
TWI832824B
(zh)
*
|
2017-10-30 |
2024-02-21 |
瑞士商赫孚孟拉羅股份公司 |
自單特異性抗體於活體內產生多特異性抗體之方法
|
|
WO2019089753A2
(en)
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
|
SG11202003833TA
(en)
|
2017-11-01 |
2020-05-28 |
Chugai Pharmaceutical Co Ltd |
Antibody variant and isoform with lowered biological activity
|
|
PL3704146T3
(pl)
|
2017-11-01 |
2022-03-07 |
F. Hoffmann-La Roche Ag |
Przeciwciało Contorsbody trifab
|
|
AU2018359506A1
(en)
|
2017-11-01 |
2020-04-23 |
F. Hoffmann-La Roche Ag |
Combination therapy with targeted OX40 agonists
|
|
EP3703746A1
(en)
|
2017-11-01 |
2020-09-09 |
F. Hoffmann-La Roche AG |
Novel tnf family ligand trimer-containing antigen binding molecules
|
|
WO2019086394A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
The compbody - a multivalent target binder
|
|
IL272747B2
(en)
|
2017-11-01 |
2025-04-01 |
Hoffmann La Roche |
Bispecific antibodies 1 + 2
|
|
TW201923089A
(zh)
|
2017-11-06 |
2019-06-16 |
美商建南德克公司 |
癌症之診斷及治療方法
|
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
CN112272563A
(zh)
|
2017-11-08 |
2021-01-26 |
Xencor股份有限公司 |
使用新颖抗pd-1序列的双特异性和单特异性抗体
|
|
CA3082146A1
(en)
|
2017-11-09 |
2019-05-16 |
Keros Therapeutics, Inc. |
Activin receptor type iia variants and methods of use thereof
|
|
WO2019098212A1
(en)
|
2017-11-14 |
2019-05-23 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-c1s antibodies and methods of use
|
|
MX2020004756A
(es)
|
2017-11-16 |
2020-08-20 |
Novartis Ag |
Terapias de combinacion.
|
|
US11851497B2
(en)
|
2017-11-20 |
2023-12-26 |
Compass Therapeutics Llc |
CD137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
AU2018371114A1
(en)
|
2017-11-21 |
2020-05-07 |
Innate Pharma |
Multispecific antigen binding proteins
|
|
IL275426B2
(en)
|
2017-12-19 |
2025-03-01 |
Xencor Inc |
Engineered il-2 fc fusion proteins
|
|
EP3502140A1
(en)
|
2017-12-21 |
2019-06-26 |
F. Hoffmann-La Roche AG |
Combination therapy of tumor targeted icos agonists with t-cell bispecific molecules
|
|
TWI805665B
(zh)
|
2017-12-21 |
2023-06-21 |
瑞士商赫孚孟拉羅股份公司 |
結合hla-a2/wt1之抗體
|
|
WO2019126472A1
(en)
|
2017-12-22 |
2019-06-27 |
Genentech, Inc. |
Use of pilra binding agents for treatment of a disease
|
|
JP7074859B2
(ja)
|
2017-12-22 |
2022-05-24 |
エフ．ホフマン－ラ ロシュ アーゲー |
疎水性相互作用クロマトグラフィーによる軽鎖誤対合抗体変種の枯渇の方法
|
|
EP3732202A4
(en)
|
2017-12-28 |
2022-06-15 |
Nanjing Legend Biotech Co., Ltd. |
SINGLE DOMAIN ANTIBODIES AND VARIANTS THEREOF AGAINST TIGIT
|
|
US12168688B2
(en)
|
2017-12-28 |
2024-12-17 |
Nanjing Legend Biotech Co., Ltd. |
Antibodies and variants thereof against PD-L1
|
|
CN111511400B
(zh)
|
2017-12-29 |
2025-08-29 |
豪夫迈·罗氏有限公司 |
抗vegf抗体及其使用方法
|
|
WO2019133512A1
(en)
|
2017-12-29 |
2019-07-04 |
Alector Llc |
Anti-tmem106b antibodies and methods of use thereof
|
|
AU2019205330B2
(en)
|
2018-01-04 |
2025-09-11 |
Iconic Therapeutics Llc |
Anti-tissue factor antibodies, antibody-drug conjugates, and related methods
|
|
EP3737692A4
(en)
|
2018-01-09 |
2021-09-29 |
Elstar Therapeutics, Inc. |
CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES
|
|
JP7394767B2
(ja)
|
2018-01-12 |
2023-12-08 |
ジェンザイム・コーポレーション |
ポリペプチドの定量化方法
|
|
EP3740507A4
(en)
|
2018-01-15 |
2022-08-24 |
Nanjing Legend Biotech Co., Ltd. |
SINGLE DOMAIN ANTIBODIES AND VARIANTS THEREOF AGAINST PD-1
|
|
US20200339686A1
(en)
|
2018-01-16 |
2020-10-29 |
Lakepharma, Inc. |
Bispecific antibody that binds cd3 and another target
|
|
JP2021510740A
(ja)
|
2018-01-24 |
2021-04-30 |
ゲンマブ ビー．ブイ． |
ポリペプチド変種およびそれらの用途
|
|
WO2019149715A1
(en)
|
2018-01-31 |
2019-08-08 |
F. Hoffmann-La Roche Ag |
Stabilized immunoglobulin domains
|
|
US11472874B2
(en)
|
2018-01-31 |
2022-10-18 |
Alector Llc |
Anti-MS4A4A antibodies and methods of use thereof
|
|
AU2019215031B2
(en)
|
2018-01-31 |
2025-10-09 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
JP2021511793A
(ja)
|
2018-01-31 |
2021-05-13 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
Ｌａｇ３に結合する抗原結合部位を含む二重特異性抗体
|
|
WO2019148410A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1 antibodies
|
|
WO2019148412A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1/lag3 bispecific antibodies
|
|
CN111699004A
(zh)
|
2018-02-06 |
2020-09-22 |
豪夫迈·罗氏有限公司 |
眼科疾病的治疗
|
|
PT3749346T
(pt)
|
2018-02-08 |
2024-09-05 |
Dragonfly Therapeutics Inc |
Combinações de domínios variáveis de anticorpos dirigidas ao receptor nkg2d
|
|
CN118772288A
(zh)
|
2018-02-08 |
2024-10-15 |
豪夫迈·罗氏有限公司 |
双特异性抗原结合分子和使用方法
|
|
KR20200118824A
(ko)
|
2018-02-08 |
2020-10-16 |
드래곤플라이 쎄라퓨틱스, 인크. |
자연 살해 세포를 활성화시키는 다중-특이성 결합 단백질을 수반하는 암의 병용 요법
|
|
WO2019153200A1
(zh)
|
2018-02-08 |
2019-08-15 |
北京韩美药品有限公司 |
抗pd-1/抗her2天然抗体结构样异源二聚体形式双特异抗体及其制备
|
|
KR102417088B1
(ko)
|
2018-02-09 |
2022-07-07 |
제넨테크, 인크. |
비만 세포 매개 염증성 질환에 대한 치료 및 진단 방법
|
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
|
JP2021512624A
(ja)
|
2018-02-11 |
2021-05-20 |
ベイジン・ハンミ・ファーマシューティカル・カンパニー・リミテッドＢｅｉｊｉｎｇ Ｈａｎｍｉ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． |
抗ｐｄ−１／抗ｖｅｇｆ天然抗体構造様ヘテロ二量体型二重特異性抗体及びその製造
|
|
JP7466442B2
(ja)
|
2018-02-14 |
2024-04-12 |
中外製薬株式会社 |
抗原結合分子および組合せ
|
|
CA3091424A1
(en)
|
2018-02-20 |
2019-08-29 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use
|
|
CR20250348A
(es)
|
2018-03-12 |
2025-09-23 |
Genmab As |
ANTICUERPOS QUE SE UNEN A 5T4 (Divisional 2020-463)
|
|
PL3765489T3
(pl)
|
2018-03-13 |
2025-02-10 |
F. Hoffmann-La Roche Ag |
Terapeutyczne połączenie agonistów 4-1BB z przeciwciałami anty-CD20
|
|
TWI841551B
(zh)
|
2018-03-13 |
2024-05-11 |
瑞士商赫孚孟拉羅股份公司 |
使用靶向4-1bb (cd137)之促效劑的組合療法
|
|
EP3765517A1
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
EP3765516A2
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
|
US20200040103A1
(en)
|
2018-03-14 |
2020-02-06 |
Genentech, Inc. |
Anti-klk5 antibodies and methods of use
|
|
JP7508368B2
(ja)
|
2018-03-15 |
2024-07-01 |
中外製薬株式会社 |
ジカウイルスに対して交差反応性を有する抗デングウイルス抗体および使用方法
|
|
JP2021519073A
(ja)
|
2018-03-29 |
2021-08-10 |
ジェネンテック， インコーポレイテッド |
哺乳動物細胞におけるラクトジェニック活性の制御
|
|
CN111886254B
(zh)
|
2018-03-30 |
2023-12-08 |
南京传奇生物科技有限公司 |
针对lag-3的单结构域抗体及其用途
|
|
EP3778639A4
(en)
|
2018-04-02 |
2021-06-09 |
Mab-Venture Biopharm Co., Ltd. |
LYMPHOCYTE ANTIGEN-3 (LAG-3) BINDING ANTIBODY AND ITS USES
|
|
TW202011029A
(zh)
|
2018-04-04 |
2020-03-16 |
美商建南德克公司 |
偵測及定量fgf21之方法
|
|
AU2019247415A1
(en)
|
2018-04-04 |
2020-10-22 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
|
BR112020020823A2
(pt)
|
2018-04-09 |
2021-01-19 |
Amgen Inc. |
Proteínas de fusão do fator de diferenciação do crescimento 15
|
|
IL323061A
(en)
|
2018-04-11 |
2025-10-01 |
Inhibrx Biosciences Inc |
Multispecific polypeptide constructs with forced CD3 binding and related methods and uses
|
|
PE20210652A1
(es)
|
2018-04-13 |
2021-03-26 |
Hoffmann La Roche |
Moleculas de union a antigeno dirigidas a her2 que comprenden 4-1bbl
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
EP3781598A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
|
|
AR114789A1
(es)
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
|
KR20210010862A
(ko)
|
2018-04-18 |
2021-01-28 |
젠코어 인코포레이티드 |
IL-15/IL-15Rα Fc-융합 단백질 및 PD-1 항원 결합 도메인을 함유하는 PD-1 표적화 이종이량체 융합 단백질 및 이의 용도
|
|
MA52289A
(fr)
|
2018-04-18 |
2021-02-24 |
Xencor Inc |
Protéines de fusion fc hétérodimères il-15/il-15ra et leurs utilisations
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
WO2019211472A1
(en)
|
2018-05-03 |
2019-11-07 |
Genmab B.V. |
Antibody variant combinations and uses thereof
|
|
EP3794132A1
(en)
|
2018-05-18 |
2021-03-24 |
F. Hoffmann-La Roche AG |
Targeted intracellular delivery of large nucleic acids
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
CN112384534A
(zh)
|
2018-05-21 |
2021-02-19 |
指南针制药有限责任公司 |
用于增强nk细胞对靶细胞的杀死的组合物和方法
|
|
PE20210342A1
(es)
|
2018-05-25 |
2021-02-23 |
Alector Llc |
Anticuerpos anti-sirpa y metodos de utilizacion de los mismos
|
|
WO2019227003A1
(en)
|
2018-05-25 |
2019-11-28 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
BR112020024351A2
(pt)
|
2018-06-01 |
2021-02-23 |
Novartis Ag |
moléculas de ligação contra bcma e usos das mesmas
|
|
TWI851577B
(zh)
|
2018-06-07 |
2024-08-11 |
美商思進公司 |
喜樹鹼結合物
|
|
TWI848953B
(zh)
|
2018-06-09 |
2024-07-21 |
德商百靈佳殷格翰國際股份有限公司 |
針對癌症治療之多特異性結合蛋白
|
|
MY208825A
(en)
|
2018-06-13 |
2025-05-30 |
Novartis Ag |
Bcma chimeric antigen receptors and uses thereof
|
|
WO2019245991A1
(en)
|
2018-06-18 |
2019-12-26 |
Eureka Therapeutics, Inc. |
Constructs targeting prostate-specific membrane antigen (psma) and uses thereof
|
|
EP3810269A2
(en)
|
2018-06-19 |
2021-04-28 |
Atarga, LLC |
Antibody molecules to complement component 5 and uses thereof
|
|
JP7513530B2
(ja)
|
2018-06-22 |
2024-07-09 |
ジェンマブ ホールディング ビー．ブイ． |
抗ｃｄ３７抗体および抗ｃｄ２０抗体、組成物、ならびにそれらの使用方法
|
|
CN112384532B
(zh)
|
2018-06-29 |
2025-01-10 |
艾利妥 |
抗SIRP-β1抗体及其使用方法
|
|
EP3818083A2
(en)
|
2018-07-03 |
2021-05-12 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
WO2020007817A1
(en)
|
2018-07-04 |
2020-01-09 |
F. Hoffmann-La Roche Ag |
Novel bispecific agonistic 4-1bb antigen binding molecules
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
MA53123A
(fr)
|
2018-07-13 |
2021-05-19 |
Genmab As |
Thérapie à médiation par trogocytose utilisant des anticorps cd38
|
|
KR102530517B1
(ko)
|
2018-07-13 |
2023-05-09 |
알렉터 엘엘씨 |
항-소틸린 항체 및 이들의 사용 방법
|
|
KR20210031932A
(ko)
|
2018-07-13 |
2021-03-23 |
젠맵 에이/에스 |
Cd38 항체의 변이체 및 그의 용도
|
|
JP7072715B2
(ja)
|
2018-07-20 |
2022-05-20 |
サーフィス オンコロジー インコーポレイテッド |
抗ｃｄ１１２ｒ組成物及び方法
|
|
WO2020023553A1
(en)
|
2018-07-24 |
2020-01-30 |
Inhibrx, Inc. |
Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
SG11202101152QA
(en)
|
2018-08-03 |
2021-03-30 |
Chugai Pharmaceutical Co Ltd |
Antigen-binding molecule containing two antigen-binding domains that are linked to each other
|
|
CA3108646A1
(en)
|
2018-08-08 |
2020-02-13 |
Dragonfly Therapeutics, Inc. |
Proteins binding nkg2d, cd16 and a tumor-associated antigen
|
|
EA202091888A1
(ru)
|
2018-08-08 |
2020-10-23 |
Драгонфлай Терапьютикс, Инк. |
Вариабельные домены антител, нацеленные на рецептор nkg2d
|
|
AU2019318083A1
(en)
|
2018-08-08 |
2021-02-25 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins that bind BCMA, NKG2D and CD16, and methods of use
|
|
CA3051549A1
(en)
|
2018-08-09 |
2020-02-09 |
Regeneron Pharmaceuticals, Inc. |
Methods for assessing binding affinity of an antibody variant to the neonatal fc receptor
|
|
CN112839960B
(zh)
|
2018-08-10 |
2024-09-06 |
中外制药株式会社 |
抗cd137抗原结合分子及其应用
|
|
TW202021618A
(zh)
|
2018-08-17 |
2020-06-16 |
美商２３與我有限公司 |
抗ｉｌ１ｒａｐ抗體及其使用方法
|
|
JP7523349B2
(ja)
|
2018-08-29 |
2024-07-26 |
中外製薬株式会社 |
抗体半分子、および抗体半分子のホモ二量体形成を抑制する方法
|
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
|
MX2021002573A
(es)
|
2018-09-10 |
2021-05-12 |
Genentech Inc |
Sistemas y procedimientos para electroforesis capilar de afinidad.
|
|
US11573226B2
(en)
|
2018-09-10 |
2023-02-07 |
Genentech, Inc. |
Systems and methods for affinity capillary electrophoresis
|
|
CN112673022B
(zh)
|
2018-09-10 |
2024-07-09 |
南京传奇生物科技有限公司 |
针对cd33的单结构域抗体及其构建体
|
|
JP2022501332A
(ja)
|
2018-09-19 |
2022-01-06 |
ジェネンテック， インコーポレイテッド |
膀胱がんの治療方法および診断方法
|
|
WO2020068774A1
(en)
|
2018-09-24 |
2020-04-02 |
The Medical College Of Wisconsin, Inc. |
System and method for the development of cd30 bispecific antibodies for immunotherapy of cd30+ malignancies
|
|
CN112955468B
(zh)
|
2018-10-01 |
2024-08-09 |
豪夫迈·罗氏有限公司 |
包含抗fap克隆212的双特异性抗原结合分子
|
|
JP2022511396A
(ja)
|
2018-10-01 |
2022-01-31 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
Ｃｄ４０への三価結合を伴う二重特異性抗原結合分子
|
|
JP7612571B2
(ja)
|
2018-10-03 |
2025-01-14 |
ゼンコア インコーポレイテッド |
Ｉｌ－１２ヘテロ二量体ｆｃ－融合タンパク質
|
|
WO2020070313A1
(en)
|
2018-10-04 |
2020-04-09 |
Genmab Holding B.V. |
Pharmaceutical compositions comprising bispecific anti-cd37 antibodies
|
|
WO2020076970A1
(en)
|
2018-10-11 |
2020-04-16 |
Inhibrx, Inc. |
B7h3 single domain antibodies and therapeutic compositions thereof
|
|
JP7453219B2
(ja)
|
2018-10-11 |
2024-03-19 |
インヒブリックス， インコーポレイテッド |
Ｐｄ－１単一ドメイン抗体およびその治療用組成物
|
|
CN113166263A
(zh)
|
2018-10-11 |
2021-07-23 |
印希比股份有限公司 |
Dll3单域抗体及其治疗性组合物
|
|
CA3114693A1
(en)
|
2018-10-11 |
2020-04-16 |
Inhibrx, Inc. |
5t4 single domain antibodies and therapeutic compositions thereof
|
|
CR20210239A
(es)
|
2018-10-12 |
2021-12-15 |
Xencor Inc |
Proteínas de fusión de il-15/il-15ralfa-fc dirigidas a pd-1 y usos de las mismas en terapias combinadas
|
|
WO2020081767A1
(en)
|
2018-10-18 |
2020-04-23 |
Genentech, Inc. |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
|
KR20210080460A
(ko)
|
2018-10-23 |
2021-06-30 |
드래곤플라이 쎄라퓨틱스, 인크. |
이종이량체성 Fc-융합된 단백질
|
|
CA3115110A1
(en)
|
2018-10-24 |
2020-04-30 |
F. Hoffmann-La Roche Ag |
Conjugated chemical inducers of degradation and methods of use
|
|
WO2020089051A1
(en)
|
2018-10-29 |
2020-05-07 |
F. Hoffmann-La Roche Ag |
Antibody formulation
|
|
US20220170097A1
(en)
|
2018-10-29 |
2022-06-02 |
The Broad Institute, Inc. |
Car t cell transcriptional atlas
|
|
WO2020094744A1
(en)
|
2018-11-06 |
2020-05-14 |
Genmab A/S |
Antibody formulation
|
|
CN113166269B
(zh)
|
2018-11-13 |
2025-01-07 |
指南针制药有限责任公司 |
对抗检查点分子的多特异性结合构建体及其用途
|
|
EP3883964A1
(en)
|
2018-11-20 |
2021-09-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Bispecific antibody targeting transferrin receptor 1 and soluble antigen
|
|
CA3121699A1
(en)
|
2018-12-05 |
2020-06-11 |
Morphosys Ag |
Multispecific antigen-binding molecules
|
|
AU2018451747A1
(en)
|
2018-12-06 |
2021-06-17 |
F. Hoffmann-La Roche Ag |
Combination therapy of diffuse large B-cell lymphoma comprising an anti-CD79b immunoconjugates, an alkylating agent and an anti-CD20 antibody
|
|
EP3894427A1
(en)
|
2018-12-10 |
2021-10-20 |
Genentech, Inc. |
Photocrosslinking peptides for site specific conjugation to fc-containing proteins
|
|
AU2019402097A1
(en)
|
2018-12-17 |
2021-06-10 |
Revitope Limited |
Twin immune cell engager
|
|
TWI874341B
(zh)
|
2018-12-18 |
2025-03-01 |
美商健生生物科技公司 |
產生異二聚體抗體之方法
|
|
BR112021011874A2
(pt)
|
2018-12-20 |
2021-09-08 |
Novartis Ag |
Regime de dosagem e combinação farmacêutica compreendendo derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona
|
|
WO2020132646A1
(en)
|
2018-12-20 |
2020-06-25 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains
|
|
AR117327A1
(es)
|
2018-12-20 |
2021-07-28 |
23Andme Inc |
Anticuerpos anti-cd96 y métodos de uso de estos
|
|
KR20210106484A
(ko)
|
2018-12-20 |
2021-08-30 |
노파르티스 아게 |
Hdm2-p53 상호작용 억제제와 bcl2 억제제의 조합 및 암 치료를 위한 이의 용도
|
|
JP2022514290A
(ja)
|
2018-12-20 |
2022-02-10 |
ジェネンテック， インコーポレイテッド |
改変抗体ｆｃおよび使用方法
|
|
CN113286822A
(zh)
|
2018-12-21 |
2021-08-20 |
豪夫迈·罗氏有限公司 |
靶向肿瘤的超激动性cd28抗原结合分子
|
|
WO2020132220A1
(en)
|
2018-12-21 |
2020-06-25 |
23Andme, Inc. |
Anti-il-36 antibodies and methods of use thereof
|
|
US11672858B2
(en)
|
2018-12-21 |
2023-06-13 |
Hoffmann-La Roche Inc. |
Bispecific antibody molecules binding to CD3 and TYRP-1
|
|
KR20210108981A
(ko)
|
2018-12-21 |
2021-09-03 |
에프. 호프만-라 로슈 아게 |
종양-표적화된 효현성 cd28 항원 결합 분자
|
|
IL319262A
(en)
|
2018-12-24 |
2025-04-01 |
Sanofi Sa |
Multispecific FAB pseudoproteins bind
|
|
MX2021007672A
(es)
|
2018-12-24 |
2021-09-30 |
Sanofi Sa |
Proteinas de union multiespecificas con dominios fab mutantes.
|
|
CN113412123A
(zh)
|
2018-12-28 |
2021-09-17 |
豪夫迈·罗氏有限公司 |
用于免疫应答增强的患者的治疗性用途的肽-mhc-i-抗体融合蛋白
|
|
CN113227789B
(zh)
|
2018-12-30 |
2024-12-24 |
豪夫迈·罗氏有限公司 |
基于pH梯度SPR的结合测定
|
|
CA3124352A1
(en)
|
2019-01-04 |
2020-07-09 |
Resolve Therapeutics, Llc |
Treatment of sjogren's disease with nuclease fusion proteins
|
|
CN113329759A
(zh)
*
|
2019-01-07 |
2021-08-31 |
沙塔克实验室有限公司 |
用于调节γδT细胞的异二聚体蛋白
|
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
|
CN113597433B
(zh)
|
2019-01-18 |
2024-12-27 |
詹森生物科技公司 |
Gprc5d嵌合抗原受体以及表达这些受体的细胞
|
|
JPWO2020153467A1
(ja)
|
2019-01-24 |
2021-12-02 |
中外製薬株式会社 |
新規がん抗原及びそれらの抗原に対する抗体
|
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
|
WO2020165833A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
AU2020222346B2
(en)
|
2019-02-15 |
2021-12-09 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
|
AU2020224154B2
(en)
|
2019-02-21 |
2025-05-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
CA3130628A1
(en)
|
2019-02-21 |
2020-08-27 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to t cells and uses thereof to treat autoimmune disorders
|
|
EP3927431A1
(en)
|
2019-02-21 |
2021-12-29 |
Marengo Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
CN119661722A
(zh)
|
2019-02-21 |
2025-03-21 |
马伦戈治疗公司 |
结合t细胞相关癌细胞的多功能分子及其用途
|
|
SG11202108955QA
(en)
|
2019-02-21 |
2021-09-29 |
Marengo Therapeutics Inc |
Antibody molecules that bind to nkp30 and uses thereof
|
|
US20220088075A1
(en)
|
2019-02-22 |
2022-03-24 |
The Trustees Of The University Of Pennsylvania |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
JOP20210233A1
(ar)
|
2019-02-26 |
2023-01-30 |
Janssen Biotech Inc |
علاجات مركبة وتطابق المريض مع الأجسام ثنائية النوعية المضادة لـ EGFR/c-Met.
|
|
BR112021016955A2
(pt)
|
2019-03-01 |
2021-11-23 |
Xencor Inc |
Composição, composição de ácido nucleico, composição de vetor de expressão, vetor de expressão, célula hospedeira, métodos de produção de um domínio de ligação de membro de família 3 de pirofosfatase/fosfodiesterase de ectonucleotídeo e de tratamento de um câncer, anticorpo anti-enpp3, e, anticorpo heterodimérico
|
|
US20220235144A1
(en)
|
2019-03-04 |
2022-07-28 |
Qilu Puget Sound Biotherapeutics Corporation |
Anti-sirp-alpha antibodies
|
|
TWI892981B
(zh)
|
2019-03-08 |
2025-08-11 |
美商建南德克公司 |
用於偵測且量化膜相關蛋白之方法
|
|
JP7730761B2
(ja)
|
2019-03-14 |
2025-08-28 |
ジェネンテック， インコーポレイテッド |
抗ＨＥＲ２ ＭＡＢと組み合わせたＨＥＲ２ｘＣＤ３二重特異性抗体によるがんの処置
|
|
EP3947440A1
(en)
|
2019-03-29 |
2022-02-09 |
F. Hoffmann-La Roche AG |
Method for generating avid-binding multispecific antibodies
|
|
PH12021552414A1
(en)
|
2019-03-29 |
2022-07-25 |
Atarga Llc |
Anti fgf23 antibody
|
|
EP3948281A1
(en)
|
2019-03-29 |
2022-02-09 |
F. Hoffmann-La Roche AG |
Spr-based binding assay for the functional analysis of multivalent molecules
|
|
EP3952996A1
(en)
|
2019-04-12 |
2022-02-16 |
F. Hoffmann-La Roche AG |
Bispecific antigen binding molecules comprising lipocalin muteins
|
|
EP3956364A1
(en)
|
2019-04-19 |
2022-02-23 |
F. Hoffmann-La Roche AG |
Anti-mertk antibodies and their methods of use
|
|
EP3959238A1
(en)
|
2019-04-25 |
2022-03-02 |
F. Hoffmann-La Roche AG |
Activatable therapeutic multispecific polypeptides with extended half-life
|
|
BR112021020843A2
(pt)
|
2019-04-25 |
2022-02-01 |
Hoffmann La Roche |
Conjunto de polipeptídeos precursores heterodiméricos, polipeptídeos heterodiméricos, métodos para gerar um polipeptídeo heterodimérico e para identificar um polipeptídeo heterodimérico multiespecífico, polipeptídeo heterodimérico multiespecífico, primeiro e segundo polipeptídeo precursor heterodimérico
|
|
WO2020216879A1
(en)
|
2019-04-25 |
2020-10-29 |
F. Hoffmann-La Roche Ag |
Therapeutic multispecific polypeptides activated by polypeptide chain exchange
|
|
BR112021021972A2
(pt)
|
2019-05-03 |
2021-12-21 |
Hoffmann La Roche |
Métodos de redução de uma taxa de atividade de hidrólise enzimática, de redução do nível de uma ou mais enzimas hidrolíticas e de redução da degradação de um polissorbato, composições farmacêuticas e composições de porção de anticorpo formulada
|
|
WO2020225456A1
(en)
|
2019-05-09 |
2020-11-12 |
Genmab B.V. |
Dosage regimens for a combination of anti-dr5 antibodies for use in treating cancer
|
|
AR122263A1
(es)
|
2019-05-09 |
2022-08-31 |
Genentech Inc |
Métodos para producir anticuerpos
|
|
EP3969907B1
(en)
|
2019-05-13 |
2025-09-24 |
F. Hoffmann-La Roche AG |
Interference-suppressed pharmacokinetic immunoassay
|
|
TW202108178A
(zh)
|
2019-05-14 |
2021-03-01 |
美商建南德克公司 |
使用抗CD79b免疫結合物治療濾泡性淋巴瘤之方法
|
|
WO2020236797A1
(en)
|
2019-05-21 |
2020-11-26 |
Novartis Ag |
Variant cd58 domains and uses thereof
|
|
KR102878895B1
(ko)
|
2019-05-21 |
2025-10-31 |
노파르티스 아게 |
Cd19 결합 분자 및 이의 용도
|
|
JP7664183B2
(ja)
|
2019-05-21 |
2025-04-17 |
ノバルティス アーゲー |
Ｂｃｍａに対する三重特異性結合分子及びその使用
|
|
JP7710997B2
(ja)
|
2019-05-31 |
2025-07-22 |
エーエルエックス オンコロジー インコーポレイテッド |
免疫チェックポイント阻害剤と組み合わせてｓｉｒｐアルファｆｃ融合によりがんを治療する方法
|
|
MA56131A
(fr)
|
2019-06-10 |
2022-04-13 |
Chugai Pharmaceutical Co Ltd |
Molécule de liaison à l'antigène anti-lymphocytes t à utiliser en association avec un inhibiteur de cytokines
|
|
MX2021015212A
(es)
|
2019-06-11 |
2022-04-06 |
Alector Llc |
Anticuerpos antisortilina para uso en terapia.
|
|
EP3986924A1
(en)
|
2019-06-19 |
2022-04-27 |
F. Hoffmann-La Roche AG |
Method for the generation of a multivalent, multispecific antibody expressing cell by targeted integration of multiple expression cassettes in a defined organization
|
|
CN114080451B
(zh)
|
2019-06-19 |
2024-03-22 |
豪夫迈·罗氏有限公司 |
通过使用Cre mRNA进行的靶向整合来产生蛋白质表达细胞的方法
|
|
JP2022537202A
(ja)
|
2019-06-19 |
2022-08-24 |
エフ．ホフマン－ラ ロシュ アーゲー |
所定の構成の複数の発現カセットの標的指向性組込みによって多価二重特異性抗体発現細胞を作製するための方法
|
|
KR20220024637A
(ko)
|
2019-06-19 |
2022-03-03 |
에프. 호프만-라 로슈 아게 |
정의된 조직의 다수 발현 카세트들의 표적화 통합에 의한 3가 항체 발현 세포의 생성 방법
|
|
MX2021015538A
(es)
|
2019-06-19 |
2022-02-10 |
Hoffmann La Roche |
Metodo para la generacion de una celula que expresa un anticuerpo biespecifico bivalente mediante la integracion dirigida de multiples casetes de expresion en una organizacion definida.
|
|
ES3027485T3
(en)
|
2019-06-26 |
2025-06-16 |
Hoffmann La Roche |
Mammalian cell lines with sirt-1 gene knockout
|
|
AU2020304813A1
(en)
|
2019-06-26 |
2022-01-06 |
F. Hoffmann-La Roche Ag |
Fusion of an antibody binding CEA and 4-1BBL
|
|
EP3990492A1
(en)
|
2019-06-27 |
2022-05-04 |
F. Hoffmann-La Roche AG |
Novel icos antibodies and tumor-targeted antigen binding molecules comprising them
|
|
AU2020304671A1
(en)
|
2019-06-28 |
2022-01-20 |
Amgen Inc. |
Anti-CGRP receptor/anti-PAC1 receptor bispecific antigen binding proteins
|
|
JP2022538139A
(ja)
|
2019-07-02 |
2022-08-31 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
変異体インターロイキン－２及び抗ｃｄ８抗体を含む免疫複合体
|
|
AR119382A1
(es)
|
2019-07-12 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos de pre-direccionamiento y métodos de uso
|
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
|
US20230107034A1
(en)
|
2019-07-16 |
2023-04-06 |
The Brigham And Women's Hospital, Inc. |
Neutralizing anti-amyloid beta antibodies for the treatment of alzheimer's disease
|
|
CN114174338A
(zh)
|
2019-07-31 |
2022-03-11 |
豪夫迈·罗氏有限公司 |
与gprc5d结合的抗体
|
|
MX2022001156A
(es)
|
2019-07-31 |
2022-02-22 |
Hoffmann La Roche |
Anticuerpos que se fijan a gprc5d.
|
|
JP7612658B2
(ja)
|
2019-07-31 |
2025-01-14 |
アレクトル エルエルシー |
抗ｍｓ４ａ４ａ抗体、及びその使用方法
|
|
CA3148740A1
(en)
|
2019-08-06 |
2021-02-11 |
Aprinoia Therapeutics Limited |
Antibodies that bind to pathological tau species and uses thereof
|
|
EP4010371A1
(en)
|
2019-08-08 |
2022-06-15 |
Regeneron Pharmaceuticals, Inc. |
Novel antigen binding molecule formats
|
|
CR20220111A
(es)
|
2019-08-13 |
2022-05-04 |
Amgen Inc |
Muteínas de interleucina-2 para la expansión de células t reguladoras referencia cruzada a solicitudes relacionadas
|
|
MX2022002612A
(es)
|
2019-09-03 |
2022-05-06 |
Amgen Inc |
Composiciones de il-22 orales, intrarrectales u otras relacionadas con el intestino y metodos de uso de las mismas.
|
|
MX2022002963A
(es)
|
2019-09-12 |
2022-04-06 |
Genentech Inc |
Composiciones y metodos para tratar nefritis lupica.
|
|
JP2022549087A
(ja)
|
2019-09-18 |
2022-11-24 |
ジェネンテック， インコーポレイテッド |
抗ｋｌｋ７抗体、抗ｋｌｋ５抗体、多重特異性抗ｋｌｋ５／ｋｌｋ７抗体および使用方法
|
|
WO2021055694A1
(en)
|
2019-09-20 |
2021-03-25 |
Genentech, Inc. |
Dosing for anti-tryptase antibodies
|
|
EP4036116A4
(en)
|
2019-09-27 |
2024-01-24 |
Nanjing GenScript Biotech Co., Ltd. |
ANTI-VHH DOMAIN ANTIBODIES AND USE THEREOF
|
|
TWI878355B
(zh)
|
2019-10-02 |
2025-04-01 |
德商百靈佳殷格翰國際股份有限公司 |
用於癌症治療之多重專一性結合蛋白
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
WO2021076196A1
(en)
|
2019-10-18 |
2021-04-22 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
|
CN114786679A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
具有维奈托克和tim-3抑制剂的组合疗法
|
|
JP2022553306A
(ja)
|
2019-10-21 |
2022-12-22 |
ノバルティス アーゲー |
Ｔｉｍ－３阻害剤およびその使用
|
|
TW202134277A
(zh)
|
2019-11-05 |
2021-09-16 |
美商再生元醫藥公司 |
Ｎ—端ｓｃＦｖ多特異性結合分子
|
|
EP4055046A1
(en)
|
2019-11-06 |
2022-09-14 |
Genmab B.V. |
Antibody variant combinations and uses thereof
|
|
EP4055060B1
(en)
*
|
2019-11-08 |
2025-07-09 |
Amgen Inc. |
Engineering charge pair mutations for pairing of hetero-igg molecules
|
|
TWI895295B
(zh)
|
2019-11-12 |
2025-09-01 |
美商方得生醫療公司 |
偵測編碼新生抗原之融合基因之方法
|
|
CA3152314A1
(en)
|
2019-11-15 |
2021-05-20 |
Andrea ALLMENDINGER |
Prevention of visible particle formation in aqueous protein solutions
|
|
KR20220114560A
(ko)
|
2019-11-18 |
2022-08-17 |
얀센 바이오테크 인코포레이티드 |
항-cd79 키메라 항원 수용체, car-t 세포 및 이의 용도
|
|
CA3160438A1
(en)
|
2019-11-19 |
2021-05-27 |
Amgen Inc. |
Novel multispecific antibody format
|
|
PH12022551291A1
(en)
|
2019-11-26 |
2023-11-20 |
Novartis Ag |
Chimeric antigen receptors binding bcma and cd19 and uses thereof
|
|
CN113135996A
(zh)
|
2019-12-09 |
2021-07-20 |
启愈生物技术(上海)有限公司 |
一种双特异抗体及其应用
|
|
AR120741A1
(es)
|
2019-12-13 |
2022-03-16 |
Genentech Inc |
Anticuerpos anti-ly6g6d y métodos de uso
|
|
MX2022007712A
(es)
|
2019-12-17 |
2022-09-26 |
Amgen Inc |
Agonista doble de interleucina-2/receptor de tnf para uso en terapia.
|
|
IL293926A
(en)
|
2019-12-17 |
2022-08-01 |
Pfizer |
Antibodies specific for cd47, pd-l1, and uses thereof
|
|
AU2020403913B2
(en)
|
2019-12-18 |
2024-10-10 |
F. Hoffmann-La Roche Ag |
Bispecific anti-CCL2 antibodies
|
|
CN114828965B
(zh)
|
2019-12-18 |
2025-09-05 |
豪夫迈·罗氏有限公司 |
与hla-a2/mage-a4结合的抗体
|
|
IL293978A
(en)
|
2019-12-20 |
2022-08-01 |
Regeneron Pharma |
New il2 agonists and methods of using them
|
|
CN115175937A
(zh)
|
2019-12-20 |
2022-10-11 |
诺华股份有限公司 |
用于治疗骨髓纤维化和骨髓增生异常综合征的抗TIM-3抗体MBG453和抗TGF-β抗体NIS793与或不与地西他滨或抗PD-1抗体斯巴达珠单抗的组合
|
|
CN114846024A
(zh)
|
2019-12-20 |
2022-08-02 |
豪夫迈·罗氏有限公司 |
Il-37融合蛋白及其用途
|
|
BR112022012439A2
(pt)
|
2019-12-23 |
2022-09-06 |
Genentech Inc |
Anticorpos isolados, ácido nucleico isolado, vetor isolado, célula hospedeira isolada e métodos para produzir um anticorpo que se liga à apol1, para detectar apolipoproteína l1 em uma amostra, para distinguir apolipoproteína l1 endógena, para distinguir as formas g0 e g1 de apolipoproteína l1 da forma apol1 g2 e para detectar especificamente células de podócitos
|
|
PH12022551580A1
(en)
|
2019-12-27 |
2023-11-20 |
Chugai Pharmaceutical Co Ltd |
Anti-ctla-4 antibody and use thereof
|
|
CN114930170A
(zh)
|
2020-01-02 |
2022-08-19 |
豪夫迈·罗氏有限公司 |
用于测定脑中的治疗性抗体量的方法
|
|
WO2021138407A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
|
GB2609554B
(en)
|
2020-01-03 |
2025-08-20 |
Marengo Therapeutics Inc |
Anti-TCR antibody molecules and uses thereof
|
|
JP7675083B2
(ja)
|
2020-01-09 |
2025-05-12 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
新規４－１ｂｂｌ三量体含有抗原結合分子
|
|
CN110818795B
(zh)
|
2020-01-10 |
2020-04-24 |
上海复宏汉霖生物技术股份有限公司 |
抗tigit抗体和使用方法
|
|
EP4090666A1
(en)
|
2020-01-15 |
2022-11-23 |
F. Hoffmann-La Roche AG |
Methods to decrease impurities from recombinant protein manufacturing processes
|
|
PE20230113A1
(es)
|
2020-01-16 |
2023-01-27 |
Genmab As |
Formulaciones de anticuerpos anti-cd38 y usos de las mismas
|
|
US20210222244A1
(en)
|
2020-01-17 |
2021-07-22 |
Becton, Dickinson And Company |
Methods and compositions for single cell secretomics
|
|
KR20220128389A
(ko)
|
2020-01-17 |
2022-09-20 |
노파르티스 아게 |
골수이형성 증후군 또는 만성 골수단핵구성 백혈병을 치료하는데 사용하기 위한 tim-3 억제제 및 저메틸화제를 포함하는 조합물
|
|
KR20220148175A
(ko)
|
2020-01-29 |
2022-11-04 |
인히브릭스, 인크. |
Ｃｄ28 단일 도메인 항체 및 이의 다가 및 다중특이적 구조체
|
|
WO2021155916A1
(en)
|
2020-02-04 |
2021-08-12 |
BioNTech SE |
Treatment involving antigen vaccination and binding agents binding to pd-l1 and cd137
|
|
EP4105238A4
(en)
|
2020-02-10 |
2024-03-27 |
Shanghai Escugen Biotechnology Co., Ltd. |
CLAUDIN 18.2 ANTIBODIES AND THEIR USE
|
|
JP7663883B2
(ja)
|
2020-02-10 |
2025-04-17 |
上海詩健生物科技有限公司 |
Ｃｌｄｎ１８．２抗体及びその使用
|
|
TWI895351B
(zh)
|
2020-02-12 |
2025-09-01 |
日商中外製藥股份有限公司 |
用於癌症之治療的抗cd137抗原結合分子
|
|
JP2023516195A
(ja)
|
2020-02-26 |
2023-04-18 |
バイオグラフ ５５，インク． |
Ｃ１９ ｃ３８二特異性抗体
|
|
WO2021173844A1
(en)
|
2020-02-26 |
2021-09-02 |
Biograph 55, Inc. |
C19 c38 bispecific antibodies
|
|
AU2021225949A1
(en)
|
2020-02-27 |
2022-09-15 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
TW202144410A
(zh)
|
2020-03-13 |
2021-12-01 |
美商建南德克公司 |
抗介白素－３３抗體及其用途
|
|
CN115298221A
(zh)
|
2020-03-18 |
2022-11-04 |
健玛保 |
结合b7h4的抗体
|
|
MX2022011455A
(es)
|
2020-03-19 |
2022-10-03 |
Genentech Inc |
Anticuerpos anti-tgf-beta con selectividad de isoforma y metodos de uso.
|
|
EP4126949A1
(en)
|
2020-03-24 |
2023-02-08 |
Genentech, Inc. |
Tie2-binding agents and methods of use
|
|
KR20220156912A
(ko)
|
2020-03-25 |
2022-11-28 |
일라이 릴리 앤드 캄파니 |
다중특이적 결합 단백질 및 그의 개발 방법
|
|
CN115315512A
(zh)
|
2020-03-26 |
2022-11-08 |
基因泰克公司 |
具有降低的宿主细胞蛋白质的经修饰的哺乳动物细胞
|
|
CN116249549A
(zh)
|
2020-03-27 |
2023-06-09 |
诺华股份有限公司 |
用于治疗增殖性疾病和自身免疫病症的双特异性组合疗法
|
|
AU2021246385A1
(en)
|
2020-03-30 |
2022-12-08 |
Daiichi Sankyo Company, Limited |
Bispecific antibody
|
|
AR121706A1
(es)
|
2020-04-01 |
2022-06-29 |
Hoffmann La Roche |
Moléculas de unión a antígeno biespecíficas dirigidas a ox40 y fap
|
|
US20240183826A9
(en)
|
2020-04-02 |
2024-06-06 |
Chugai Seiyaku Kabushiki Kaisha |
Analysis method for impurity molecules in composition containing multi-specific antigen-binding molecules
|
|
EP4127724A1
(en)
|
2020-04-03 |
2023-02-08 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
US20230192795A1
(en)
|
2020-04-15 |
2023-06-22 |
Hoffmann-La Roche Inc. |
Immunoconjugates
|
|
KR20230020394A
(ko)
|
2020-04-15 |
2023-02-10 |
보이저 테라퓨틱스, 인크. |
Tau 결합 화합물
|
|
JP2023522417A
(ja)
|
2020-04-24 |
2023-05-30 |
エフ． ホフマン－ラ ロシュ アーゲー |
スルフヒドリル化合物およびその誘導体を用いた酵素および経路調節
|
|
KR20230028242A
(ko)
|
2020-04-24 |
2023-02-28 |
마렝고 테라퓨틱스, 인크. |
T 세포 관련 암 세포에 결합하는 다중기능성 분자 및 그것의 용도
|
|
JP7785016B2
(ja)
|
2020-04-24 |
2025-12-12 |
ジェネンテック， インコーポレイテッド |
抗ＣＤ７９ｂ免疫抱合体の使用方法
|
|
JP2023523450A
(ja)
|
2020-04-28 |
2023-06-05 |
ジェネンテック， インコーポレイテッド |
非小細胞肺がん免疫療法のための方法及び組成物
|
|
CA3180173A1
(en)
|
2020-04-30 |
2021-11-04 |
Bristol-Myers Squibb Company |
Methods of treating cytokine-related adverse events
|
|
CN116096758A
(zh)
|
2020-05-01 |
2023-05-09 |
诺华股份有限公司 |
工程化免疫球蛋白
|
|
KR20230087414A
(ko)
|
2020-05-03 |
2023-06-16 |
레베나 (쑤저우) 바이오파마 컴퍼니 리미티드 |
항-Trop-2 항체를 포함하는 항체-약물 접합체 (ADCS), 상기 ADCS를 포함하는 조성물, 및 이의 제조 및 사용 방법
|
|
MX2022013944A
(es)
|
2020-05-06 |
2022-11-30 |
Dragonfly Therapeutics Inc |
Proteinas que se unen al receptor activador de celulas asesinas naturales grupo 2 miembro d (nkg2d), cumulo de diferenciacion (cd16) y miembro a de la familia de dominios de lectina tipo c 12 (clec12a).
|
|
CN115916166A
(zh)
|
2020-05-08 |
2023-04-04 |
健玛保 |
针对cd3和cd20的双特异性抗体
|
|
BR112022022614A2
(pt)
|
2020-05-11 |
2023-02-07 |
Hoffmann La Roche |
Métodos para estimular uma resposta imune, melhorar uma imunoterapia, tratar uma doença, reduzir crescimento tumoral, produzir um imunoconjugado e produzir uma composição, método de vacinação, imunoconjugados, composição, usos e kits
|
|
US11673930B2
(en)
|
2020-05-12 |
2023-06-13 |
Regeneran Pharmaceuticals, Inc. |
IL10 agonists and methods of use thereof
|
|
US11919956B2
(en)
|
2020-05-14 |
2024-03-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
|
|
EP4149421A1
(en)
|
2020-05-15 |
2023-03-22 |
F. Hoffmann-La Roche AG |
Prevention of visible particle formation in parenteral protein solutions
|
|
AU2021273789B2
(en)
|
2020-05-18 |
2024-07-18 |
Shandong Simcere Biopharmaceutical Co., Ltd. |
Human IL-15 mutant and use thereof
|
|
EP4153130A1
(en)
|
2020-05-19 |
2023-03-29 |
F. Hoffmann-La Roche AG |
The use of chelators for the prevention of visible particle formation in parenteral protein solutions
|
|
CN116249555A
(zh)
|
2020-05-19 |
2023-06-09 |
勃林格殷格翰国际有限公司 |
用于癌症治疗的结合分子
|
|
WO2021243204A1
(en)
|
2020-05-29 |
2021-12-02 |
23Andme, Inc. |
Anti-cd200r1 antibodies and methods of use thereof
|
|
CN115697489A
(zh)
|
2020-06-08 |
2023-02-03 |
豪夫迈·罗氏有限公司 |
抗hbv抗体及其使用方法
|
|
WO2021252977A1
(en)
|
2020-06-12 |
2021-12-16 |
Genentech, Inc. |
Methods and compositions for cancer immunotherapy
|
|
CN115768478A
(zh)
|
2020-06-19 |
2023-03-07 |
中外制药株式会社 |
用于和血管新生抑制剂组合使用的抗t细胞抗原结合分子
|
|
EP4168446A1
(en)
|
2020-06-19 |
2023-04-26 |
F. Hoffmann-La Roche AG |
Antibodies binding to cd3 and folr1
|
|
IL296225A
(en)
|
2020-06-19 |
2022-11-01 |
Hoffmann La Roche |
Immune activating fc domain binding molecules
|
|
MX2022016069A
(es)
|
2020-06-19 |
2023-02-02 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y cd19.
|
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
|
TW202214704A
(zh)
|
2020-06-19 |
2022-04-16 |
瑞士商赫孚孟拉羅股份公司 |
蛋白酶活化ｔ細胞雙特異性抗體
|
|
AR122658A1
(es)
|
2020-06-19 |
2022-09-28 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3
|
|
US20230235040A1
(en)
|
2020-06-22 |
2023-07-27 |
Almirall, S.A. |
Anti-il-36 antibodies and methods of use thereof
|
|
CA3182346A1
(en)
|
2020-06-23 |
2021-12-30 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
PE20231361A1
(es)
|
2020-06-23 |
2023-09-05 |
Hoffmann La Roche |
Moleculas agonistas de union al antigeno cd28 que se dirigen a her2
|
|
WO2021262783A1
(en)
|
2020-06-24 |
2021-12-30 |
Genentech, Inc. |
Apoptosis resistant cell lines
|
|
CN115916830A
(zh)
|
2020-06-25 |
2023-04-04 |
豪夫迈·罗氏有限公司 |
抗cd3/抗cd28双特异性抗原结合分子
|
|
CA3165342A1
(en)
|
2020-06-29 |
2022-01-06 |
James Arthur Posada |
Treatment of sjogren's syndrome with nuclease fusion proteins
|
|
US12295997B2
(en)
|
2020-07-06 |
2025-05-13 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
|
JP2023532764A
(ja)
|
2020-07-07 |
2023-07-31 |
エフ． ホフマン－ラ ロシュ アーゲー |
治療用タンパク質製剤の安定剤としての代替界面活性剤
|
|
BR112023000204A2
(pt)
|
2020-07-10 |
2023-01-31 |
Hoffmann La Roche |
Conjunto de anticorpos, conjunto de ácidos nucleicos, vetor de expressão, célula hospedeira, métodos de pré-direcionamento de radioimunoterapia e direcionamento de um radioisótopo, ligante peptídico, proteína de múltiplos domínios e usos
|
|
MX2023000547A
(es)
|
2020-07-16 |
2023-02-13 |
Novartis Ag |
Anticuerpos anti-betacelulina, fragmentos de los mismos, y moleculas de union multiespecificas.
|
|
WO2022016119A1
(en)
|
2020-07-17 |
2022-01-20 |
Simurx, Inc. |
Chimeric myd88 receptors for redirecting immunosuppressive signaling and related compositions and methods
|
|
MX2023000617A
(es)
|
2020-07-17 |
2023-02-13 |
Genentech Inc |
Anticuerpos anti-notch2 y metodos de uso.
|
|
MX2023000888A
(es)
|
2020-07-21 |
2023-02-22 |
Genentech Inc |
Inductores quimicos de degradacion conjugados con anticuerpo de brm y metodos de estos.
|
|
US20230293680A1
(en)
|
2020-07-23 |
2023-09-21 |
Genmab B.V. |
A composition of anti-dr5 antibodies and an immunomodulatory imide drug for use in treating multiple myeloma
|
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
|
AU2021317974A1
(en)
|
2020-07-31 |
2023-03-16 |
Chugai Seiyaku Kabushiki Kaisha |
Pharmaceutical Composition comprising Cell Expressing Chimeric Receptor
|
|
US20230271940A1
(en)
|
2020-08-03 |
2023-08-31 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
AU2021322046A1
(en)
|
2020-08-06 |
2023-02-02 |
BioNTech SE |
Binding agents for coronavirus S protein
|
|
US11919958B2
(en)
|
2020-08-19 |
2024-03-05 |
Xencor, Inc. |
Anti-CD28 compositions
|
|
WO2022047046A1
(en)
|
2020-08-26 |
2022-03-03 |
Marengo Therapeutics, Inc. |
Methods of detecting trbc1 or trbc2
|
|
CN116249718A
(zh)
|
2020-08-26 |
2023-06-09 |
马伦戈治疗公司 |
结合至钙网蛋白的多功能性分子及其用途
|
|
CN116917316A
(zh)
|
2020-08-26 |
2023-10-20 |
马伦戈治疗公司 |
与NKp30结合的抗体分子及其用途
|
|
WO2022044248A1
(ja)
|
2020-08-28 |
2022-03-03 |
中外製薬株式会社 |
ヘテロ二量体Ｆｃポリペプチド
|
|
WO2022047222A2
(en)
|
2020-08-28 |
2022-03-03 |
Genentech, Inc. |
Crispr/cas9 multiplex knockout of host cell proteins
|
|
EP4204020A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
|
US20230321285A1
(en)
|
2020-08-31 |
2023-10-12 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
CN116472060A
(zh)
|
2020-09-02 |
2023-07-21 |
健玛保 |
抗体疗法
|
|
CN116782933A
(zh)
|
2020-09-10 |
2023-09-19 |
健玛保 |
用于治疗弥漫性大b细胞淋巴瘤的联合疗法中的针对cd3和cd20的双特异性抗体
|
|
CN116406293A
(zh)
|
2020-09-10 |
2023-07-07 |
健玛保 |
用于治疗滤泡性淋巴瘤的联合疗法中的针对cd3和cd20的双特异性抗体
|
|
CA3190349A1
(en)
|
2020-09-10 |
2022-03-17 |
Brian Elliott |
Bispecific antibodies against cd3 and cd20 for treating chronic lymphocytic leukemia
|
|
JP2023542092A
(ja)
|
2020-09-10 |
2023-10-05 |
ジェンマブ エー／エス |
びまん性大細胞型ｂ細胞リンパ腫を治療するための併用療法におけるｃｄ３及びｃｄ２０に対する二重特異性抗体
|
|
CA3192251A1
(en)
|
2020-09-10 |
2022-03-17 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
|
BR112023004351A2
(pt)
|
2020-09-10 |
2023-04-04 |
Genmab As |
Método para tratar linfoma folicular em um sujeito humano
|
|
US11970539B2
(en)
|
2020-09-14 |
2024-04-30 |
Ichnos Sciences SA |
Antibodies that bind to IL1RAP and uses thereof
|
|
AU2021342566A1
(en)
|
2020-09-21 |
2023-03-02 |
Genentech, Inc. |
Purification of multispecific antibodies
|
|
IL301366A
(en)
|
2020-09-24 |
2023-05-01 |
Hoffmann La Roche |
Mammalian cell lines with gene knockout
|
|
IL301513A
(en)
|
2020-10-02 |
2023-05-01 |
Genmab As |
Antibodies capable of binding to ror2 and bispecific antibodies binding to ror2 and cd3
|
|
JP2023544407A
(ja)
|
2020-10-05 |
2023-10-23 |
ジェネンテック， インコーポレイテッド |
抗ＦｃＲＨ５／抗ＣＤ３二重特異性抗体による処置のための投与
|
|
US11926667B2
(en)
|
2020-10-13 |
2024-03-12 |
Janssen Biotech, Inc. |
Bioengineered T cell mediated immunity, materials and other methods for modulating cluster of differentiation IV and/or VIII
|
|
WO2022084210A1
(en)
|
2020-10-20 |
2022-04-28 |
F. Hoffmann-La Roche Ag |
Combination therapy of pd-1 axis binding antagonists and lrrk2 inhitibors
|
|
TW202233671A
(zh)
|
2020-10-20 |
2022-09-01 |
美商建南德克公司 |
Ｐｅｇ結合抗ｍｅｒｔｋ抗體及其使用方法
|
|
JP7633397B2
(ja)
|
2020-10-21 |
2025-02-19 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
眼の疾患の処置のための二重特異性抗ＶＥＧＦ及び抗ＴｒｋＢ結合分子
|
|
WO2022093888A1
(en)
|
2020-10-28 |
2022-05-05 |
Janssen Biotech, Inc. |
Compositions and methods for modulating delta gamma chain mediated immunity
|
|
US20230374147A1
(en)
|
2020-11-02 |
2023-11-23 |
Hummingbird Bioscience Pte. Ltd. |
Bcma/taci antigen-binding molecules
|
|
CA3199839A1
(en)
|
2020-11-06 |
2022-05-12 |
Novartis Ag |
Anti-cd19 agent and b cell targeting agent combination therapy for treating b cell malignancies
|
|
US20240025993A1
(en)
|
2020-11-06 |
2024-01-25 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
US20240010748A1
(en)
|
2020-11-10 |
2024-01-11 |
Shanghai Qilu Pharmaceutical Research And Development Centre Ltd. |
Bispecific antibody for claudin 18a2 and cd3 and application of bispecific antibody
|
|
CN116635062A
(zh)
|
2020-11-13 |
2023-08-22 |
诺华股份有限公司 |
使用表达嵌合抗原受体（car）的细胞的组合疗法
|
|
JP2023549316A
(ja)
|
2020-11-16 |
2023-11-24 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
Ｆａｐを標的としたｃｄ４０アゴニストとの併用療法
|
|
JP2023549809A
(ja)
|
2020-11-16 |
2023-11-29 |
エフ． ホフマン－ラ ロシュ アーゲー |
Ｆａｂ高マンノースグリコフォーム
|
|
KR20230117169A
(ko)
|
2020-12-02 |
2023-08-07 |
알렉터 엘엘씨 |
항-소르틸린 항체의 사용 방법
|
|
CN116635403A
(zh)
|
2020-12-04 |
2023-08-22 |
豪夫迈·罗氏有限公司 |
pH依赖性突变型白细胞介素-2多肽
|
|
US20240067758A1
(en)
|
2020-12-07 |
2024-02-29 |
UCB Biopharma SRL |
Multi-specific antibodies and antibody combinations
|
|
BR112023008265A2
(pt)
|
2020-12-07 |
2024-02-06 |
UCB Biopharma SRL |
Anticorpos contra interleucina-22
|
|
JP7326584B2
(ja)
|
2020-12-17 |
2023-08-15 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
抗ｈｌａ－ｇ抗体及びその使用
|
|
WO2022129313A1
(en)
|
2020-12-18 |
2022-06-23 |
F. Hoffmann-La Roche Ag |
Precursor proteins and kit for targeted therapy
|
|
JP2024501662A
(ja)
|
2020-12-22 |
2024-01-15 |
エフ． ホフマン－ラ ロシュ アーゲー |
Ｘｂｐ１を標的とするオリゴヌクレオチド
|
|
JP2024503826A
(ja)
|
2021-01-06 |
2024-01-29 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
Ｐｄ１－ｌａｇ３二重特異性抗体及びｃｄ２０ ｔ細胞二重特異性抗体を用いる併用療法
|
|
WO2022148853A1
(en)
|
2021-01-11 |
2022-07-14 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
|
PE20240690A1
(es)
|
2021-01-12 |
2024-04-10 |
Hoffmann La Roche |
Anticuerpos split que se unen a celulas cancerosas y dirigen radionuclidos a dichas celulas
|
|
US20240173442A1
(en)
|
2021-01-13 |
2024-05-30 |
Hoffmann-La Roche Inc. |
Combination therapy
|
|
WO2022162587A1
(en)
|
2021-01-27 |
2022-08-04 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
|
JP2024505049A
(ja)
|
2021-01-29 |
2024-02-02 |
ノバルティス アーゲー |
抗ｃｄ７３及び抗ｅｎｔｐｄ２抗体のための投与方式並びにその使用
|
|
CA3209479A1
(en)
|
2021-02-03 |
2022-08-11 |
Mozart Therapeutics, Inc. |
Binding agents and methods of using the same
|
|
EP4288458A1
(en)
|
2021-02-03 |
2023-12-13 |
Genentech, Inc. |
Multispecific binding protein degrader platform and methods of use
|
|
CN117794566A
(zh)
|
2021-02-05 |
2024-03-29 |
Vib研究所 |
沙贝病毒结合剂
|
|
BR112023016360A2
(pt)
|
2021-02-16 |
2024-01-23 |
Janssen Biotech Inc |
Materiais e métodos para determinação aprimorada de ligante alvo
|
|
EP4295154A1
(en)
|
2021-02-18 |
2023-12-27 |
F. Hoffmann-La Roche AG |
Method for resolving complex, multistep antibody interactions
|
|
KR102836732B1
(ko)
|
2021-02-19 |
2025-07-21 |
(주)샤페론 |
Pd-l1에 대한 단일 도메인 항체 및 이의 용도
|
|
WO2022177392A1
(ko)
|
2021-02-19 |
2022-08-25 |
(주)샤페론 |
Cd47에 대한 단일 도메인 항체 및 이의 용도
|
|
EP4301418A1
(en)
|
2021-03-03 |
2024-01-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates comprising an anti-bcma antibody
|
|
JP2024508894A
(ja)
|
2021-03-03 |
2024-02-28 |
ドラゴンフライ セラピューティクス， インコーポレイテッド |
Ｎｋｇ２ｄ、ｃｄ１６、及び腫瘍関連抗原に結合する多特異性結合タンパク質を使用して癌を治療する方法
|
|
US20240262913A1
(en)
|
2021-03-09 |
2024-08-08 |
Hoffmann-La Roche Inc. |
Combination therapy of pd-1-targeted il-2 variant immunoconjugate and anti-tyrp1/anti-cd3 bispecific antibodies
|
|
CN117083084A
(zh)
|
2021-03-09 |
2023-11-17 |
豪夫迈·罗氏有限公司 |
Pd-1靶向il-2变体免疫缀合物和fap/4-1bb结合分子的组合疗法
|
|
KR20230156079A
(ko)
|
2021-03-09 |
2023-11-13 |
젠코어 인코포레이티드 |
Cd3과 cldn6에 결합하는 이종이량체 항체
|
|
EP4305065A1
(en)
|
2021-03-10 |
2024-01-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and gpc3
|
|
JP2024512377A
(ja)
|
2021-03-12 |
2024-03-19 |
ジェネンテック， インコーポレイテッド |
抗ｋｌｋ７抗体、抗ｋｌｋ５抗体、多重特異性抗ｋｌｋ５／ｋｌｋ７抗体、及び使用方法
|
|
KR20230156921A
(ko)
|
2021-03-12 |
2023-11-15 |
젠맵 에이/에스 |
비-활성화 항체 변이체
|
|
MX2023010812A
(es)
|
2021-03-15 |
2023-09-27 |
Genentech Inc |
Composiciones y metodos para tratar la nefritis lupica.
|
|
WO2022197947A1
(en)
|
2021-03-18 |
2022-09-22 |
Alector Llc |
Anti-tmem106b antibodies and methods of use thereof
|
|
WO2022197877A1
(en)
|
2021-03-19 |
2022-09-22 |
Genentech, Inc. |
Methods and compositions for time delayed bio-orthogonal release of cytotoxic agents
|
|
EP4314063A1
(en)
|
2021-03-23 |
2024-02-07 |
Alector LLC |
Anti-tmem106b antibodies for treating and preventing coronavirus infections
|
|
TW202304986A
(zh)
|
2021-03-24 |
2023-02-01 |
美商健生生物科技公司 |
靶向cd22及cd79b的抗體
|
|
BR112023019205A2
(pt)
|
2021-03-26 |
2023-10-24 |
Janssen Biotech Inc |
Anticorpos humanizados contra tau de filamento helicoidal pareado e usos dos mesmos
|
|
MX2023011310A
(es)
|
2021-03-26 |
2023-10-05 |
Innate Pharma |
Anclajes de citocina para proteinas de celulas nk de union a nkp46.
|
|
MX2023011127A
(es)
|
2021-03-29 |
2023-10-04 |
Daiichi Sankyo Co Ltd |
Molecula multiespecifica estable y uso de la misma.
|
|
WO2022206872A1
(zh)
|
2021-03-31 |
2022-10-06 |
江苏恒瑞医药股份有限公司 |
截短的taci多肽及其融合蛋白和用途
|
|
TW202304994A
(zh)
|
2021-04-02 |
2023-02-01 |
美商泰尼歐生物公司 |
促效性抗ｉｌ－２ｒ抗體及使用方法
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
EP4320147A4
(en)
|
2021-04-08 |
2025-06-18 |
Marengo Therapeutics, Inc. |
TCR-BINDING MULTIFUNCTIONAL MOLECULES AND USES THEREOF
|
|
WO2022214565A1
(en)
|
2021-04-09 |
2022-10-13 |
F. Hoffmann-La Roche Ag |
Process for selecting cell clones expressing a heterologous polypeptide
|
|
TW202304524A
(zh)
|
2021-04-10 |
2023-02-01 |
美商普方生物製藥美國公司 |
Folr1結合劑、其結合物及使用方法
|
|
AR125344A1
(es)
|
2021-04-15 |
2023-07-05 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-c1s
|
|
CA3215965A1
(en)
|
2021-04-19 |
2022-10-27 |
Amy Shen |
Modified mammalian cells
|
|
AU2022262644A1
(en)
|
2021-04-23 |
2023-11-09 |
Genmab A/S |
Anti-cd70 antibodies, conjugates thereof and methods of using the same
|
|
WO2022228706A1
(en)
|
2021-04-30 |
2022-11-03 |
F. Hoffmann-La Roche Ag |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibody
|
|
AU2021443318A1
(en)
|
2021-04-30 |
2023-09-07 |
F. Hoffmann-La Roche Ag |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
|
CN117642428A
(zh)
|
2021-05-03 |
2024-03-01 |
Ucb生物制药有限责任公司 |
抗体
|
|
BR112023022878A2
(pt)
|
2021-05-04 |
2024-01-23 |
Regeneron Pharma |
Agonistas do receptor fgf21 multiespecíficos e seus usos
|
|
CN117597365A
(zh)
|
2021-05-04 |
2024-02-23 |
再生元制药公司 |
多特异性fgf21受体激动剂及其应用
|
|
MX2023012351A
(es)
|
2021-05-07 |
2023-10-31 |
Genmab As |
Composiciones farmaceuticas que comprenden anticuerpos biespecificos que se unen al inhibidor de la activacion de celulas t que contiene un dominio v-set 1 (b7h4) y cumulo de diferenciacion 3 (cd3).
|
|
WO2022238481A1
(en)
|
2021-05-11 |
2022-11-17 |
Modiquest B.V. |
Antibodies
|
|
CA3218170A1
(en)
|
2021-05-12 |
2022-11-17 |
Jamie Harue HIRATA |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
|
KR20240006586A
(ko)
|
2021-05-12 |
2024-01-15 |
지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 |
Rankl 및 ngf에 특이적으로 결합하는 항원 결합 분자, 및 이의 의학적 용도
|
|
IL308400A
(en)
|
2021-05-13 |
2024-01-01 |
Alx Oncology Inc |
Combined therapies for cancer treatment
|
|
US20240392020A1
(en)
|
2021-05-14 |
2024-11-28 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Antigen-binding molecule
|
|
BR112023023777A2
(pt)
|
2021-05-14 |
2024-01-30 |
Genentech Inc |
Anticorpos isolados, composição farmacêutica, ácido nucleico isolado, vetor isolado, célula hospedeira isolada, método para produzir um anticorpo, método para tratar uma condição associada à perda de função de trem2, método para reduzir os níveis de strem2 e uso de um anticorpo
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
WO2022243261A1
(en)
|
2021-05-19 |
2022-11-24 |
F. Hoffmann-La Roche Ag |
Agonistic cd40 antigen binding molecules targeting cea
|
|
KR20240010469A
(ko)
|
2021-05-21 |
2024-01-23 |
제넨테크, 인크. |
관심 재조합 생성물의 생성을 위한 변형된 세포
|
|
CN113278071B
(zh)
|
2021-05-27 |
2021-12-21 |
江苏荃信生物医药股份有限公司 |
抗人干扰素α受体1单克隆抗体及其应用
|
|
AR126009A1
(es)
|
2021-06-02 |
2023-08-30 |
Hoffmann La Roche |
Moléculas agonistas de unión al antígeno cd28 que se dirigen a epcam
|
|
WO2022255440A1
(en)
|
2021-06-04 |
2022-12-08 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-ddr2 antibodies and uses thereof
|
|
WO2022258691A1
(en)
|
2021-06-09 |
2022-12-15 |
Innate Pharma |
Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a
|
|
WO2022258600A1
(en)
|
2021-06-09 |
2022-12-15 |
F. Hoffmann-La Roche Ag |
Combination of a particular braf inhibitor (paradox breaker) and a pd-1 axis binding antagonist for use in the treatment of cancer
|
|
MX2023014645A
(es)
|
2021-06-09 |
2024-01-31 |
Innate Pharma |
Proteinas acopladoras de celulas nk de union a nkp46 especificas de cd20.
|
|
WO2022258678A1
(en)
|
2021-06-09 |
2022-12-15 |
Innate Pharma |
Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a
|
|
BR112023025331A2
(pt)
|
2021-06-09 |
2024-02-27 |
Innate Pharma |
Proteína multiespecífica, composição farmacêutica, célula recombinante, ácido nucleico ou conjunto de ácidos nucleicos, uso de uma proteína ou composição, métodos ou uso
|
|
CN117642426A
(zh)
|
2021-06-16 |
2024-03-01 |
艾莱克特有限责任公司 |
双特异性抗MerTK和抗PDL1抗体及其使用方法
|
|
EP4355783A1
(en)
|
2021-06-16 |
2024-04-24 |
Alector LLC |
Monovalent anti-mertk antibodies and methods of use thereof
|
|
JP2024523033A
(ja)
|
2021-06-17 |
2024-06-25 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
新規の三重特異的結合分子
|
|
WO2022263638A1
(en)
|
2021-06-17 |
2022-12-22 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
|
AU2022295067A1
(en)
|
2021-06-18 |
2023-12-21 |
F. Hoffmann-La Roche Ag |
Bispecific anti-ccl2 antibodies
|
|
IL309319A
(en)
|
2021-06-21 |
2024-02-01 |
Genmab As |
Combined dosage regimen CD137 and PD-L1 binding agents
|
|
IL308134A
(en)
|
2021-06-22 |
2023-12-01 |
Novartis Ag |
BISPECIFIC ANTIBODIES FOR USE IN THE TREATMENT OF HIDRADENITIS SUPPURATIVA
|
|
TW202306999A
(zh)
|
2021-06-24 |
2023-02-16 |
美商艾瑞斯卡公司 |
抗egfr抗體及其用途
|
|
TWI861519B
(zh)
|
2021-06-25 |
2024-11-11 |
日商中外製藥股份有限公司 |
抗ctla-4抗體
|
|
US12448451B2
(en)
|
2021-06-25 |
2025-10-21 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-CTLA-4 antibody and use thereof
|
|
CN117545779B
(zh)
|
2021-06-25 |
2025-04-04 |
中外制药株式会社 |
抗ctla-4抗体的用途
|
|
EP4365199A4
(en)
|
2021-06-29 |
2025-02-26 |
Shandong Simcere Biopharmaceutical Co., Ltd. |
Cd16 antibody and use thereof
|
|
TW202309078A
(zh)
|
2021-07-02 |
2023-03-01 |
美商建南德克公司 |
治療癌症之方法及組成物
|
|
TW202320857A
(zh)
|
2021-07-06 |
2023-06-01 |
美商普方生物製藥美國公司 |
連接子、藥物連接子及其結合物及其使用方法
|
|
JP2024527589A
(ja)
|
2021-07-09 |
2024-07-25 |
ルクセンブルク インスティテュート オブ ヘルス（エルアイエイチ） |
二量体タンパク質複合体及びその使用
|
|
WO2023287663A1
(en)
|
2021-07-13 |
2023-01-19 |
Genentech, Inc. |
Multi-variate model for predicting cytokine release syndrome
|
|
JP2024528573A
(ja)
|
2021-07-14 |
2024-07-30 |
江蘇恒瑞医薬股▲ふん▼有限公司 |
Ｈｇｆｒとｅｇｆｒに特異的に結合する抗原結合分子及びその医薬使用
|
|
KR20240032889A
(ko)
|
2021-07-14 |
2024-03-12 |
제넨테크, 인크. |
항-c-c 모티프 케모카인 수용체 8(ccr8) 항체 및 사용 방법
|
|
US20250066441A1
(en)
|
2021-07-19 |
2025-02-27 |
Regeneron Pharmaceuticals, Inc. |
Il12 receptor agonists and methods of use thereof
|
|
WO2023001884A1
(en)
|
2021-07-22 |
2023-01-26 |
F. Hoffmann-La Roche Ag |
Heterodimeric fc domain antibodies
|
|
JP2024526880A
(ja)
|
2021-07-22 |
2024-07-19 |
ジェネンテック， インコーポレイテッド |
脳標的化組成物及びその使用方法
|
|
WO2023006809A1
(en)
|
2021-07-27 |
2023-02-02 |
Morphosys Ag |
Combinations of antigen binding molecules
|
|
WO2023010060A2
(en)
|
2021-07-27 |
2023-02-02 |
Novab, Inc. |
Engineered vlrb antibodies with immune effector functions
|
|
CN117715936A
(zh)
|
2021-07-28 |
2024-03-15 |
豪夫迈·罗氏有限公司 |
用于治疗癌症的方法和组合物
|
|
WO2023012147A1
(en)
|
2021-08-03 |
2023-02-09 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies and methods of use
|
|
WO2023019239A1
(en)
|
2021-08-13 |
2023-02-16 |
Genentech, Inc. |
Dosing for anti-tryptase antibodies
|
|
WO2023022965A2
(en)
|
2021-08-16 |
2023-02-23 |
Regeneron Pharmaceuticals, Inc. |
Novel il27 receptor agonists and methods of use thereof
|
|
AU2022332285A1
(en)
|
2021-08-23 |
2024-02-15 |
Immunitas Therapeutics, Inc. |
Anti-cd161 antibodies and uses thereof
|
|
CA3228359A1
(en)
|
2021-08-27 |
2023-03-02 |
Genentech, Inc. |
Methods of treating tau pathologies
|
|
JP2024534853A
(ja)
|
2021-08-30 |
2024-09-26 |
ジェネンテック， インコーポレイテッド |
抗ポリビキチン多重特異性抗体
|
|
CN113603775B
(zh)
|
2021-09-03 |
2022-05-20 |
江苏荃信生物医药股份有限公司 |
抗人白介素-33单克隆抗体及其应用
|
|
CN113683694B
(zh)
|
2021-09-03 |
2022-05-13 |
江苏荃信生物医药股份有限公司 |
一种抗人tslp单克隆抗体及其应用
|
|
EP4399227A1
(en)
|
2021-09-06 |
2024-07-17 |
Genmab A/S |
Antibodies capable of binding to cd27, variants thereof and uses thereof
|
|
EP4405396A2
(en)
|
2021-09-20 |
2024-07-31 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
EP4406968A4
(en)
|
2021-09-23 |
2025-03-12 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
ANTI-KLB ANTIBODIES AND USES
|
|
CA3233261A1
(en)
|
2021-09-30 |
2023-04-06 |
Langyong MAO |
Anti-il23 antibody fusion protein and uses thereof
|
|
CN115975043B
(zh)
*
|
2021-09-30 |
2024-07-12 |
宁波三生生物科技股份有限公司 |
重组促卵泡激素融合蛋白
|
|
IL311805A
(en)
|
2021-10-08 |
2024-05-01 |
Genmab As |
Antibodies that bind to CD30 and CD3
|
|
JPWO2023058723A1
(cg-RX-API-DMAC7.html)
|
2021-10-08 |
2023-04-13 |
|
|
|
JP2024537096A
(ja)
|
2021-10-14 |
2024-10-10 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
がんの治療のための代替的なＰＤ１－ＩＬ７ｖイムノコンジュゲート
|
|
PE20241627A1
(es)
|
2021-10-14 |
2024-08-07 |
Hoffmann La Roche |
Nuevos inmunoconjugados de interleucina-7
|
|
UY39981A
(es)
|
2021-10-14 |
2023-07-31 |
Teneobio Inc |
Proteínas de unión a la mesotelina y usos de las mismas
|
|
JP2024542939A
(ja)
|
2021-10-15 |
2024-11-19 |
リジェネクスバイオ インコーポレイテッド |
抗体及びその使用方法
|
|
CA3234552A1
(en)
|
2021-10-20 |
2023-04-27 |
Synthekine, Inc. |
Heterodimeric fc cytokines and uses thereof
|
|
WO2023076876A1
(en)
|
2021-10-26 |
2023-05-04 |
Mozart Therapeutics, Inc. |
Modulation of immune responses to viral vectors
|
|
JP2024541905A
(ja)
|
2021-10-28 |
2024-11-13 |
ノバルティス アーゲー |
人工操作Ｆｃバリアント
|
|
WO2023086807A1
(en)
|
2021-11-10 |
2023-05-19 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
|
TW202334223A
(zh)
|
2021-11-11 |
2023-09-01 |
美商再生元醫藥公司 |
Ｃｄ２０－ｐｄ１結合分子及其使用方法
|
|
WO2023092004A1
(en)
|
2021-11-17 |
2023-05-25 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
EP4437344A1
(en)
|
2021-11-25 |
2024-10-02 |
F. Hoffmann-La Roche AG |
Quantification of low amounts of antibody sideproducts
|
|
CN118284625A
(zh)
|
2021-11-26 |
2024-07-02 |
豪夫迈·罗氏有限公司 |
抗tyrp1/抗cd3双特异性抗体与tyrp1特异性抗体的组合疗法
|
|
AU2022401024A1
(en)
|
2021-11-30 |
2024-05-16 |
Daiichi Sankyo Company, Limited |
Protease-cleavable masked antibodies
|
|
IL313202A
(en)
|
2021-12-01 |
2024-07-01 |
Chugai Pharmaceutical Co Ltd |
A method for preparing a formulation containing an antibody
|
|
WO2023098846A1
(zh)
|
2021-12-03 |
2023-06-08 |
江苏先声药业有限公司 |
抗bcma纳米抗体及其应用
|
|
AR127887A1
(es)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y plap
|
|
EP4448578A1
(en)
|
2021-12-17 |
2024-10-23 |
Shanghai Henlius Biotech, Inc. |
Anti-ox40 antibodies, multispecific antibodies and methods of use
|
|
KR20240122784A
(ko)
|
2021-12-17 |
2024-08-13 |
상하이 헨리우스 바이오테크, 인크. |
항-ox40 항체 및 사용 방법
|
|
CR20240246A
(es)
|
2021-12-20 |
2024-07-19 |
Hoffmann La Roche |
Anticuerpos agonistas anti-ltbr y anticuerpos biespecificos que los comprenden
|
|
EP4416301B1
(en)
|
2021-12-21 |
2025-06-11 |
F. Hoffmann-La Roche AG |
Method for the determination of hydrolytic activity
|
|
TW202346346A
(zh)
|
2021-12-23 |
2023-12-01 |
大陸商江蘇恆瑞醫藥股份有限公司 |
抗ｄｌｌ３抗體、其抗體－藥物偶聯物及其醫藥用途
|
|
US20250145705A1
(en)
|
2021-12-31 |
2025-05-08 |
Shandong Simcere Biopharmaceutical Co., Ltd. |
Gprc5d antibody and application thereof
|
|
CA3248241A1
(en)
|
2022-01-12 |
2023-07-20 |
Vib Vzw |
HUMAN NTCP BINDERS FOR THERAPEUTIC USE AND TARGETED LIVER ADMINISTRATION
|
|
TW202340251A
(zh)
|
2022-01-19 |
2023-10-16 |
美商建南德克公司 |
抗ｎｏｔｃｈ２抗體及結合物及其使用方法
|
|
AR128331A1
(es)
|
2022-01-26 |
2024-04-17 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpos y métodos de estos
|
|
AR128330A1
(es)
|
2022-01-26 |
2024-04-17 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpo y métodos de estos
|
|
JP2025503177A
(ja)
|
2022-01-28 |
2025-01-30 |
ジェンマブ エー／エス |
びまん性大細胞型ｂ細胞リンパ腫を治療するための併用療法におけるｃｄ３及びｃｄ２０に対する二重特異性抗体
|
|
WO2023144290A1
(en)
|
2022-01-28 |
2023-08-03 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
|
WO2023147784A1
(zh)
|
2022-02-07 |
2023-08-10 |
江苏恒瑞医药股份有限公司 |
特异性结合psma和cd3的抗原结合分子及其医药用途
|
|
JP2025505650A
(ja)
|
2022-02-07 |
2025-02-28 |
ビステラ， インコーポレイテッド |
抗イディオタイプ抗体分子及びその使用
|
|
EP4477674A1
(en)
|
2022-02-09 |
2024-12-18 |
Daiichi Sankyo Company, Limited |
Environmentally responsive masked antibody and use thereof
|
|
MX2024009715A
(es)
|
2022-02-11 |
2024-08-19 |
Jiangsu Hengrui Pharmaceuticals Co Ltd |
Inmunoconjugado y su uso del mismo.
|
|
MX2024010773A
(es)
|
2022-03-03 |
2024-09-10 |
Pfizer |
Anticuerpos multiespecificos y usos de estos.
|
|
WO2024026472A2
(en)
|
2022-07-29 |
2024-02-01 |
Alector Llc |
Transferrin receptor antigen-binding domains and uses therefor
|
|
JP2025509286A
(ja)
|
2022-03-10 |
2025-04-11 |
ビバソル， インコーポレイテッド |
抗体－薬物コンジュゲートおよびその使用
|
|
CN119173530A
(zh)
|
2022-03-11 |
2024-12-20 |
詹森药业有限公司 |
多特异性抗体及其用途
|
|
CN119173532A
(zh)
|
2022-03-11 |
2024-12-20 |
詹森药业有限公司 |
多特异性抗体及其用途
|
|
CN119173531A
(zh)
|
2022-03-11 |
2024-12-20 |
詹森药业有限公司 |
多特异性抗体及其用途
|
|
US20250215083A1
(en)
|
2022-03-14 |
2025-07-03 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Antigen-binding molecule specifically binding to gprc5d and cd3 and medical use thereof
|
|
WO2023174521A1
(en)
|
2022-03-15 |
2023-09-21 |
Genmab A/S |
Binding agents binding to epcam and cd137
|
|
JPWO2023176881A1
(cg-RX-API-DMAC7.html)
|
2022-03-16 |
2023-09-21 |
|
|
|
US20250197496A1
(en)
|
2022-03-18 |
2025-06-19 |
Evolvelmmune Therapeutics, Inc. |
Bispecific antibody fusion molecules and methods of use thereof
|
|
KR20240164782A
(ko)
|
2022-03-23 |
2024-11-20 |
에프. 호프만-라 로슈 아게 |
항-cd20/항-cd3 이중특이적 항체와 화학요법의 병용 치료
|
|
KR20240163119A
(ko)
|
2022-03-25 |
2024-11-18 |
상하이 헨리우스 바이오테크, 인크. |
항-msln 항체 및 사용 방법
|
|
AR128876A1
(es)
|
2022-03-28 |
2024-06-19 |
Hoffmann La Roche |
Anticuerpos biespecíficos de linfocitos t activables con proteasa folr1 mejorados
|
|
CA3246312A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
DOSAGE FOR TREATMENT WITH BISOPECIFIC ANTI-FCRH5/ANTI-CD3 ANTIBODIES
|
|
KR20250004768A
(ko)
|
2022-04-13 |
2025-01-08 |
제넨테크, 인크. |
치료 단백질의 약학적 조성물 및 사용 방법
|
|
CA3255366A1
(en)
|
2022-04-13 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions based on bispecific anti-CD20/anti-CD3 antibodies and methods of use
|
|
WO2023198839A2
(en)
|
2022-04-13 |
2023-10-19 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20
|
|
WO2023202967A1
(en)
|
2022-04-19 |
2023-10-26 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
|
AR129136A1
(es)
|
2022-04-26 |
2024-07-17 |
Novartis Ag |
Anticuerpos multiespecíficos que se dirigen a il-13 e il-18
|
|
IL316445A
(en)
|
2022-04-26 |
2024-12-01 |
Chugai Pharmaceutical Co Ltd |
A syringe containing a pharmaceutical preparation equipped with a filter
|
|
TW202406934A
(zh)
|
2022-05-03 |
2024-02-16 |
美商建南德克公司 |
抗Ｌｙ６Ｅ抗體、免疫結合物及其用途
|
|
WO2023220647A1
(en)
|
2022-05-11 |
2023-11-16 |
Regeneron Pharmaceuticals, Inc. |
Multispecific binding molecule proproteins and uses thereof
|
|
US20240059799A1
(en)
|
2022-05-11 |
2024-02-22 |
Pfizer Inc. |
Anti-tl1a antibodies and methods of use thereof
|
|
AU2022458320A1
(en)
|
2022-05-11 |
2024-11-28 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
JP2025516633A
(ja)
|
2022-05-12 |
2025-05-30 |
ジェンマブ エー／エス |
併用療法においてｃｄ２７に結合する能力を有する結合剤
|
|
CA3253038A1
(en)
|
2022-05-12 |
2023-11-16 |
Genmab A/S |
LIAISON AGENTS CAPABLE OF BINDING TO CD27 IN POLYTHERAPY
|
|
EP4522757A2
(en)
|
2022-05-13 |
2025-03-19 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
AU2023276766A1
(en)
|
2022-05-27 |
2024-12-05 |
Regeneron Pharmaceuticals, Inc. |
Interleukin-2 proproteins and uses thereof
|
|
EP4532526A1
(en)
|
2022-06-03 |
2025-04-09 |
F. Hoffmann-La Roche AG |
Improved production cells
|
|
IL317373A
(en)
|
2022-06-04 |
2025-02-01 |
Regeneron Pharma |
Interleukin-2 proproteins and their uses
|
|
WO2023236889A1
(zh)
|
2022-06-06 |
2023-12-14 |
山东先声生物制药有限公司 |
靶向bcma、gprc5d和t细胞的多特异性抗体及其应用
|
|
WO2023246885A1
(zh)
|
2022-06-23 |
2023-12-28 |
江苏恒瑞医药股份有限公司 |
特异性结合dll3和cd3的抗原结合分子及其医药用途
|
|
CA3261147A1
(en)
|
2022-07-13 |
2024-01-18 |
Genentech, Inc. |
DOSAGE FOR TREATMENT WITH BISOPECIFIC ANTI-FCRH5/ANTI-CD3 ANTIBODIES
|
|
JP2025523031A
(ja)
|
2022-07-15 |
2025-07-17 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
がんの処置のための結合性分子
|
|
WO2024020432A1
(en)
|
2022-07-19 |
2024-01-25 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
AR129995A1
(es)
|
2022-07-22 |
2024-10-23 |
Genentech Inc |
Moléculas de unión al antígeno anti-steap1 y sus usos
|
|
KR20250040994A
(ko)
|
2022-07-22 |
2025-03-25 |
브리스톨-마이어스 스큅 컴퍼니 |
인간 pad4에 결합하는 항체 및 그의 용도
|
|
AU2023312905A1
(en)
|
2022-07-27 |
2025-01-16 |
Teneobio, Inc. |
Mesothelin binding proteins and uses thereof
|
|
EP4561614A1
(en)
|
2022-07-29 |
2025-06-04 |
Alector LLC |
Cd98hc antigen-binding domains and uses therefor
|
|
TW202435912A
(zh)
|
2022-08-03 |
2024-09-16 |
美商航海家醫療公司 |
用於穿過血腦屏障之組合物及方法
|
|
JP2025525829A
(ja)
|
2022-08-03 |
2025-08-07 |
ファイザー・インク |
抗ｉｌ２７ｒ抗体およびその使用の方法
|
|
WO2024030956A2
(en)
|
2022-08-03 |
2024-02-08 |
Mozart Therapeutics, Inc. |
Cd39-specific binding agents and methods of using the same
|
|
JP2025525885A
(ja)
|
2022-08-05 |
2025-08-07 |
江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 |
Ｇｕｃｙ２ｃとｃｄ３に特異的に結合する抗原結合分子及びその医薬的使用
|
|
EP4573110A1
(en)
|
2022-08-18 |
2025-06-25 |
Regeneron Pharmaceuticals, Inc. |
Interferon proproteins and uses thereof
|
|
US20240067691A1
(en)
|
2022-08-18 |
2024-02-29 |
Regeneron Pharmaceuticals, Inc. |
Interferon receptor agonists and uses thereof
|
|
CN120153254A
(zh)
|
2022-09-01 |
2025-06-13 |
基因泰克公司 |
膀胱癌的治疗和诊断方法
|
|
EP4584297A1
(en)
|
2022-09-11 |
2025-07-16 |
Yeda Research and Development Co. Ltd |
Anti-klk4 antibodies and uses thereof
|
|
JP2025535203A
(ja)
|
2022-09-15 |
2025-10-23 |
ボイジャー セラピューティクス インコーポレイテッド |
タウ結合化合物
|
|
CN120322463A
(zh)
|
2022-09-15 |
2025-07-15 |
艾维迪治疗知识产权有限公司 |
用于nk细胞的肿瘤靶向的多特异性抗原结合蛋白及其用途
|
|
JP2025533570A
(ja)
|
2022-09-28 |
2025-10-07 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
改良されたプロテアーゼ活性化型ｔ細胞二重特異性抗体
|
|
WO2024068996A1
(en)
|
2022-09-30 |
2024-04-04 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
|
JP2025535042A
(ja)
|
2022-10-05 |
2025-10-22 |
アムジェン インコーポレイテッド |
Ｔ細胞リダイレクト療法及びアゴニスト抗ｉｌ－２ｒ抗体又はその断片を含む組み合わせ療法
|
|
KR20250084938A
(ko)
|
2022-10-07 |
2025-06-11 |
제넨테크, 인크. |
항-c-c 모티프 케모킨 수용체 8(ccr8) 항체를 이용한 암 치료 방법
|
|
TW202430211A
(zh)
|
2022-10-10 |
2024-08-01 |
瑞士商赫孚孟拉羅股份公司 |
Ｇｐｒｃ５ｄ ｔｃｂ及ｉｍｉｄ之組合療法
|
|
TW202423969A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Ｇｐｒｃ５ｄ ｔｃｂ及蛋白酶體抑制劑之組合療法
|
|
TW202423970A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Ｇｐｒｃ５ｄ ｔｃｂ及ｃｄ３８抗體之組合療法
|
|
CN120019277A
(zh)
|
2022-10-12 |
2025-05-16 |
豪夫迈·罗氏有限公司 |
用于对细胞进行分类的方法
|
|
WO2024086796A1
(en)
|
2022-10-20 |
2024-04-25 |
Alector Llc |
Anti-ms4a4a antibodies with amyloid-beta therapies
|
|
CN115724975A
(zh)
|
2022-10-20 |
2023-03-03 |
江苏荃信生物医药股份有限公司 |
抗人白介素36受体单克隆抗体及其应用
|
|
KR20250093336A
(ko)
|
2022-10-25 |
2025-06-24 |
제넨테크, 인크. |
다발성 골수종에 대한 치료 및 진단 방법
|
|
EP4612177A1
(en)
|
2022-10-31 |
2025-09-10 |
Genmab A/S |
Cd38 antibodies and uses thereof
|
|
TW202432596A
(zh)
|
2022-11-01 |
2024-08-16 |
大陸商上海齊魯製藥研究中心有限公司 |
針對磷脂醯肌醇蛋白聚醣3的雙特異性抗體及其應用
|
|
EP4612179A1
(en)
|
2022-11-02 |
2025-09-10 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20 for treating richter's syndrome
|
|
JP2025541593A
(ja)
|
2022-11-03 |
2025-12-22 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
抗ｃｄ１９／抗ｃｄ２８二重特異性抗体による併用療法
|
|
AU2023375342A1
(en)
|
2022-11-08 |
2025-04-24 |
F. Hoffmann-La Roche Ag |
Compositions and methods of treating childhood onset idiopathic nephrotic syndrome
|
|
KR20250134582A
(ko)
|
2022-11-10 |
2025-09-11 |
이뮤비아 인코포레이티드 |
Dr5 및 muc16에 결합하는 세포독성 이중특이성 항체 및 이의 용도
|
|
WO2024102948A1
(en)
|
2022-11-11 |
2024-05-16 |
Celgene Corporation |
Fc receptor-homolog 5 (fcrh5) specific binding molecules and bispecific t-cell engaging antibodies including same and related methods
|
|
WO2024100170A1
(en)
|
2022-11-11 |
2024-05-16 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a*02/foxp3
|
|
JP2025537782A
(ja)
|
2022-11-15 |
2025-11-20 |
エフ． ホフマン－ラ ロシュ アーゲー |
活性化可能なエフェクタードメインを有する組換え結合タンパク質
|
|
WO2024104933A1
(en)
|
2022-11-15 |
2024-05-23 |
F. Hoffmann-La Roche Ag |
Antigen binding molecules
|
|
TW202435917A
(zh)
|
2022-11-17 |
2024-09-16 |
美商西雅圖遺傳學公司 |
Ceacam5抗體-藥物接合物及其使用方法
|
|
EP4623086A1
(en)
|
2022-11-23 |
2025-10-01 |
F. Hoffmann-La Roche AG |
Method for increasing recombinant protein expression
|
|
AR131163A1
(es)
|
2022-11-25 |
2025-02-19 |
Chugai Pharmaceutical Co Ltd |
Métodos para producir proteínas
|
|
CN120077072A
(zh)
|
2022-11-29 |
2025-05-30 |
江苏恒瑞医药股份有限公司 |
Cldn18.2/4-1bb结合蛋白及其医药用途
|
|
EP4631974A1
(en)
|
2022-12-08 |
2025-10-15 |
Nanjing Vazyme Biotech Co., Ltd. |
Antibody specifically binding to rsv
|
|
WO2024129594A1
(en)
|
2022-12-12 |
2024-06-20 |
Genentech, Inc. |
Optimizing polypeptide sialic acid content
|
|
EP4385999A1
(en)
|
2022-12-14 |
2024-06-19 |
ModiQuest B.V. |
Antibodies
|
|
WO2024126660A1
(en)
|
2022-12-15 |
2024-06-20 |
F. Hoffmann-La Roche Ag |
Combination therapy for cancer treatment
|
|
KR20250134733A
(ko)
|
2022-12-16 |
2025-09-11 |
리제너론 파아마슈티컬스, 인크. |
Aav 입자에 결합하는 항원-결합 분자 및 용도
|
|
US20240252601A1
(en)
|
2022-12-23 |
2024-08-01 |
Regeneron Pharmaceuticals, Inc. |
Ace2 fusion proteins and uses thereof
|
|
WO2024152014A1
(en)
|
2023-01-13 |
2024-07-18 |
Regeneron Pharmaceuticals, Inc. |
Fgfr3 binding molecules and methods of use thereof
|
|
CN121013860A
(zh)
|
2023-01-13 |
2025-11-25 |
再生元制药公司 |
Il12受体激动剂及其使用方法
|
|
AU2024209001A1
(en)
|
2023-01-18 |
2025-07-24 |
Genentech, Inc. |
Multispecific antibodies and uses thereof
|
|
EP4651885A1
(en)
|
2023-01-20 |
2025-11-26 |
F. Hoffmann-La Roche AG |
Recombinant fc domain - il2 variant polypeptides and combination therapy with membrane-anchored antigen binding polypeptides
|
|
EP4655315A1
(en)
|
2023-01-25 |
2025-12-03 |
F. Hoffmann-La Roche AG |
Payload-bearing multispecific antibodies
|
|
WO2024156672A1
(en)
|
2023-01-25 |
2024-08-02 |
F. Hoffmann-La Roche Ag |
Antibodies binding to csf1r and cd3
|
|
TW202436339A
(zh)
|
2023-01-31 |
2024-09-16 |
瑞士商赫孚孟拉羅股份公司 |
治療選自非小細胞肺癌或三陰性乳癌的癌症之用途
|
|
WO2024163009A1
(en)
|
2023-01-31 |
2024-08-08 |
Genentech, Inc. |
Methods and compositions for treating urothelial bladder cancer
|
|
CN120584138A
(zh)
|
2023-02-06 |
2025-09-02 |
豪夫迈·罗氏有限公司 |
组合疗法及其用途
|
|
WO2024168061A2
(en)
|
2023-02-07 |
2024-08-15 |
Ayan Therapeutics Inc. |
Antibody molecules binding to sars-cov-2
|
|
AU2024226611A1
(en)
|
2023-02-21 |
2025-08-28 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Il-36r binding protein and medicinal use thereof
|
|
EP4669669A1
(en)
|
2023-02-21 |
2025-12-31 |
Teneobio, Inc. |
C-KIT BINDING PROTEINS, CHIMERIC ANTIGENIC RECEPTORS AND THEIR USES
|
|
WO2024179470A1
(zh)
|
2023-02-27 |
2024-09-06 |
苏州盛迪亚生物医药有限公司 |
抗dll3抗体、其抗体-药物偶联物及其医药用途
|
|
WO2024182540A2
(en)
|
2023-02-28 |
2024-09-06 |
Regeneron Pharmaceuticals, Inc. |
T cell activators and methods of use thereof
|
|
IL322940A
(en)
|
2023-02-28 |
2025-10-01 |
Regeneron Pharma |
Multivalent anti-spike protein binding molecules and their uses
|
|
WO2024184287A1
(en)
|
2023-03-06 |
2024-09-12 |
F. Hoffmann-La Roche Ag |
Combination therapy of an anti-egfrviii/anti-cd3 antibody and an tumor-targeted 4-1bb agonist
|
|
WO2024191785A1
(en)
|
2023-03-10 |
2024-09-19 |
Genentech, Inc. |
Fusions with proteases and uses thereof
|
|
WO2024188965A1
(en)
|
2023-03-13 |
2024-09-19 |
F. Hoffmann-La Roche Ag |
Combination therapy employing a pd1-lag3 bispecific antibody and an hla-g t cell bispecific antibody
|
|
TW202440636A
(zh)
|
2023-03-21 |
2024-10-16 |
美商傳記５５有限公司 |
Ｃｄ１９／ｃｄ３８多特異性抗體
|
|
WO2024206788A1
(en)
|
2023-03-31 |
2024-10-03 |
Genentech, Inc. |
Anti-alpha v beta 8 integrin antibodies and methods of use
|
|
CN120917044A
(zh)
|
2023-04-03 |
2025-11-07 |
豪夫迈·罗氏有限公司 |
激动性拆分型抗体
|
|
WO2024208777A1
(en)
|
2023-04-03 |
2024-10-10 |
F. Hoffmann-La Roche Ag |
All-in-one agonistic antibodies
|
|
TW202506178A
(zh)
|
2023-04-05 |
2025-02-16 |
丹麥商珍美寶股份有限公司 |
包含與ｃｄ３０和ｃｄ３結合之抗體之醫藥組成物
|
|
WO2024211236A2
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
WO2024211234A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
WO2024211235A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
EP4442275A1
(en)
|
2023-04-06 |
2024-10-09 |
ModiQuest B.V. |
Anti-type ii collagen antibodies
|
|
WO2024213040A1
(zh)
|
2023-04-11 |
2024-10-17 |
浙江博锐生物制药有限公司 |
抗ror1抗体及其药物偶联物
|
|
KR20250169618A
(ko)
|
2023-04-13 |
2025-12-03 |
젠맵 에이/에스 |
Cd3 및 cd20에 대한 이중특이적 항체를 사용하여 림프종을 치료하는 방법
|
|
CN121038814A
(zh)
|
2023-04-14 |
2025-11-28 |
中外制药株式会社 |
用于稳定含蛋白质药物制剂的方法
|
|
WO2024220546A2
(en)
|
2023-04-17 |
2024-10-24 |
Peak Bio, Inc. |
Antibodies and antibody-drug conjugates and methods of use and synthetic processes and intermediates
|
|
AU2024270495A1
(en)
|
2023-05-05 |
2025-10-09 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
AR132623A1
(es)
|
2023-05-08 |
2025-07-16 |
Hoffmann La Roche |
PROTEÍNAS DE FUSIÓN DE INTERFERÓN a DIRIGIDAS Y MÉTODOS DE USO
|
|
WO2024233646A1
(en)
|
2023-05-10 |
2024-11-14 |
Genentech, Inc. |
Methods and compositions for treating cancer
|
|
WO2024233926A1
(en)
|
2023-05-10 |
2024-11-14 |
Regeneron Pharmaceuticals, Inc. |
Cd20-pd1 binding molecules and methods of use thereof
|
|
AU2024271605A1
(en)
|
2023-05-12 |
2025-11-13 |
BioNTech SE |
Antibodies capable of binding to ox40, variants thereof and uses thereof
|
|
US20240376229A1
(en)
|
2023-05-12 |
2024-11-14 |
Regeneron Pharmaceuticals, Inc. |
Interferon receptor antagonists and uses thereof
|
|
AU2024273454A1
(en)
|
2023-05-16 |
2025-11-27 |
F. Hoffmann-La Roche Ag |
Pd-1-regulated il-2 immunocytokine and uses thereof
|
|
WO2024243423A1
(en)
|
2023-05-24 |
2024-11-28 |
Mozart Therapeutics, Inc. |
Cd8-specific binding proteins and methods of using the same
|
|
WO2024246086A1
(en)
|
2023-06-01 |
2024-12-05 |
F. Hoffmann-La Roche Ag |
Immunostimulatory antigen binding molecules that specifically bind to bcma
|
|
WO2024246083A1
(en)
|
2023-06-01 |
2024-12-05 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies targeting bcma and cd28
|
|
WO2024251884A1
(en)
|
2023-06-09 |
2024-12-12 |
Innate Pharma |
Nk cell engager proteins comprising anti-cd20 and ant-nkp46 antibody, linked to il-2 in treatment of r/r b-nhl
|
|
US20250011449A1
(en)
|
2023-06-11 |
2025-01-09 |
Regeneron Pharmaceuticals, Inc. |
Circularized antibody molecules
|
|
AU2024305352A1
(en)
|
2023-06-12 |
2025-12-04 |
Amgen Inc. |
Lymphotoxin beta receptor agonist binding proteins
|
|
WO2024256623A1
(en)
|
2023-06-16 |
2024-12-19 |
Heidelberg Immunotherapeutics Gmbh |
Novel anti-hsv antibody
|
|
WO2024261013A1
(en)
|
2023-06-21 |
2024-12-26 |
F. Hoffmann-La Roche Ag |
Combination therapy with fap-targeted lymphotoxin beta receptor agonists
|
|
TW202502809A
(zh)
|
2023-06-22 |
2025-01-16 |
美商建南德克公司 |
抗體及其用途
|
|
TW202504929A
(zh)
|
2023-06-22 |
2025-02-01 |
美商建南德克公司 |
用於癌症治療之方法及組成物
|
|
WO2024263195A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2024263904A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
AU2024307352A1
(en)
|
2023-06-27 |
2025-12-11 |
Amgen Inc. |
Charge pair mutations to enable correct heavy-light chain pairing
|
|
WO2025007037A1
(en)
|
2023-06-28 |
2025-01-02 |
Dragonfly Therapeutics, Inc. |
Variant il-2 proteins
|
|
JP2025530208A
(ja)
|
2023-06-30 |
2025-09-11 |
ジェンマブ エー／エス |
線維芽細胞活性化タンパク質アルファおよびデスレセプター４に結合する抗体
|
|
WO2025010272A1
(en)
*
|
2023-07-03 |
2025-01-09 |
Neoimmunetech, Inc. |
Heterodimeric fc molecules and uses thereof
|
|
US12319747B2
(en)
|
2023-07-03 |
2025-06-03 |
Medicovestor, Inc. |
Methods of using anti-SP17 immunotherapeutics
|
|
WO2025024265A1
(en)
|
2023-07-21 |
2025-01-30 |
Bristol-Myers Squibb Company |
Methods of assessing citrullination and activity of pad4 modulators
|
|
WO2025021838A1
(en)
|
2023-07-26 |
2025-01-30 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3
|
|
WO2025027511A1
(en)
|
2023-07-30 |
2025-02-06 |
Janssen Biotech, Inc. |
Molecules that bind to mutant calreticulin and uses thereof
|
|
WO2025034806A1
(en)
|
2023-08-08 |
2025-02-13 |
Wisconsin Alumni Research Foundation |
Single-domain antibodies and variants thereof against fibroblast activation protein
|
|
WO2025032071A1
(en)
|
2023-08-09 |
2025-02-13 |
F. Hoffmann-La Roche Ag |
Mono and multispecific anti-trem2 antibodies, methods and uses thereof
|
|
WO2025032069A1
(en)
|
2023-08-09 |
2025-02-13 |
F. Hoffmann-La Roche Ag |
Mono and multispecific anti-trem2 antibodies, methods and uses thereof
|
|
US20250051434A1
(en)
|
2023-08-11 |
2025-02-13 |
Merck Sharp & Dohme Llc |
Monovalent interleukin 12 (il-12) heterodimeric fc proteins
|
|
WO2025036892A1
(en)
|
2023-08-14 |
2025-02-20 |
Morphosys Ag |
Cycat halfbody molecules comprising sterically occluding moieties
|
|
WO2025038668A1
(en)
|
2023-08-14 |
2025-02-20 |
Voro Therapeutics, Inc. |
Therapeutic binding agents that conditionally promote myeloid cell activity against target cells and uses thereof
|
|
EP4630457A1
(en)
|
2023-08-18 |
2025-10-15 |
Regeneron Pharmaceuticals, Inc. |
Bispecific antigen-binding molecules and uses thereof
|
|
WO2025042742A1
(en)
|
2023-08-18 |
2025-02-27 |
Bristol-Myers Squibb Company |
Compositions comprising antibodies that bind bcma and cd3 and methods of treatment
|
|
WO2025040567A1
(en)
|
2023-08-18 |
2025-02-27 |
F. Hoffmann-La Roche Ag |
Protease activatable fc domain binding molecules
|
|
TW202525845A
(zh)
|
2023-08-23 |
2025-07-01 |
法商賽諾菲公司 |
基於ｃｔｌａ—４之溶體降解劑及其用途
|
|
TW202525856A
(zh)
|
2023-09-08 |
2025-07-01 |
美商Ｍｌａｂ生物科學有限公司 |
雙功能性蛋白質及其用途
|
|
WO2025059037A1
(en)
|
2023-09-11 |
2025-03-20 |
Evolveimmune Therapeutics, Inc. |
Bispecific antibody fusion molecules targeting b7-h4 and cd3 and methods of use thereof
|
|
WO2025059162A1
(en)
|
2023-09-11 |
2025-03-20 |
Dana-Farber Cancer Institute, Inc. |
Car-engager containing il-2 variants to enhance the functionality of car t cells
|
|
WO2025056180A1
(en)
|
2023-09-15 |
2025-03-20 |
BioNTech SE |
Methods of treatment using agents binding to epcam and cd137 in combination with pd-1 axis binding antagonists
|
|
WO2025064890A1
(en)
|
2023-09-20 |
2025-03-27 |
Evolveimmune Therapeutics, Inc. |
Bispecific antibody fusion molecules targeting cd180 and cd3 and methods of use thereof
|
|
WO2025064885A1
(en)
|
2023-09-20 |
2025-03-27 |
Evolveimmune Therapeutics, Inc. |
Multispecific antibodies that bind cd3 and cd2 and methods of use thereof
|
|
AR133909A1
(es)
|
2023-09-25 |
2025-11-12 |
Hoffmann La Roche |
ANTICUERPO QUE SE UNE A C3bBb
|
|
WO2025072406A1
(en)
|
2023-09-26 |
2025-04-03 |
Profoundbio Us Co. |
Ptk7 binding agents, conjugates thereof and methods of using the same
|
|
WO2025068957A1
(en)
|
2023-09-29 |
2025-04-03 |
Novartis Ag |
Bispecific antibodies for use in lowering the risk of cardiovascular disease events in subjects known to be a carrier of clonal expansion of hematopoietic cell lines with somatic mutations
|
|
WO2025082777A1
(en)
|
2023-10-17 |
2025-04-24 |
Morphosys Ag |
Dual-targeting of muc16 and mesothelin co-expressing tumor cells by functional complementation of cycat® halfbody molecules
|
|
WO2025085489A1
(en)
|
2023-10-17 |
2025-04-24 |
Bristol-Myers Squibb Company |
Gspt1-degrading compounds, anti-cd33 antibodies and antibody-drug conjugates and uses thereof
|
|
US12364777B2
(en)
|
2023-10-20 |
2025-07-22 |
Medicovestor, Inc. |
Homodimeric antibodies for use in treating cancers and methods of use
|
|
WO2025099632A1
(en)
|
2023-11-08 |
2025-05-15 |
Sanofi |
Cd25 based lysosomal degrader and uses thereof
|
|
US20250154287A1
(en)
|
2023-11-10 |
2025-05-15 |
Pfizer Inc. |
ANTI-MIGIS-alpha ANTIBODIES AND METHODS OF USE THEREOF
|
|
WO2025106474A1
(en)
|
2023-11-14 |
2025-05-22 |
Genentech, Inc. |
Therapeutic and diagnostic methods for treating cancer with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2025106469A1
(en)
|
2023-11-14 |
2025-05-22 |
Regeneron Pharmaceuticals, Inc. |
Engineered heavy chain variable domains and uses thereof
|
|
WO2025106634A1
(en)
|
2023-11-17 |
2025-05-22 |
Genentech, Inc. |
Mcl-1 inhibitor compounds and use in antibody drug conjugates
|
|
WO2025114541A1
(en)
|
2023-11-30 |
2025-06-05 |
Genmab A/S |
Antibodies capable of binding to ox40 in combination therapy
|
|
WO2025113643A1
(en)
|
2023-12-01 |
2025-06-05 |
Gilead Sciences Inc. |
Anti-fap-light fusion protein and use thereof
|
|
US20250179137A1
(en)
|
2023-12-05 |
2025-06-05 |
Regeneron Pharmaceuticals, Inc. |
Il18 receptor agonists and methods of use thereof
|
|
WO2025122634A1
(en)
|
2023-12-05 |
2025-06-12 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
WO2025125118A1
(en)
|
2023-12-11 |
2025-06-19 |
F. Hoffmann-La Roche Ag |
Protease activatable fc domain binding molecules
|
|
WO2025129010A1
(en)
|
2023-12-14 |
2025-06-19 |
Genentech, Inc. |
Methods of structure determination using antibodies
|
|
WO2025125386A1
(en)
|
2023-12-14 |
2025-06-19 |
F. Hoffmann-La Roche Ag |
Antibodies that bind to folr1 and methods of use
|
|
WO2025137086A1
(en)
|
2023-12-20 |
2025-06-26 |
Genentech, Inc. |
Reducing alpha-gal
|
|
WO2025132503A1
(en)
|
2023-12-20 |
2025-06-26 |
F. Hoffmann-La Roche Ag |
Antibodies binding to ceacam5
|
|
WO2025137454A1
(en)
|
2023-12-21 |
2025-06-26 |
Amgen Inc. |
Stabilizing homodimer mutations for two cell heterodimer production
|
|
WO2025133042A2
(en)
|
2023-12-22 |
2025-06-26 |
F. Hoffmann-La Roche Ag |
Activatable fusion proteins and methods of use
|
|
US12116410B1
(en)
|
2023-12-26 |
2024-10-15 |
Medicovestor, Inc. |
Methods of manufacturing dimeric antibodies
|
|
US12121587B1
(en)
|
2023-12-26 |
2024-10-22 |
Medicovestor, Inc. |
Dimeric antibodies
|
|
WO2025147696A1
(en)
|
2024-01-05 |
2025-07-10 |
Resolve Therapeutics, Llc |
Treatment of symptoms associated with sars-cov viral infection or a prior sars-cov viral infection with nuclease agents
|
|
US20250296992A1
(en)
|
2024-01-10 |
2025-09-25 |
Genmab A/S |
Slitrk6 binding agents, conjugates thereof and methods of using the same
|
|
WO2025149633A1
(en)
|
2024-01-12 |
2025-07-17 |
Laigo Bio B.V. |
Bispecific antigen binding proteins
|
|
WO2025166042A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Cd98hc antigen-binding domains and uses therefor
|
|
WO2025166040A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Multi-specific binding proteins that bind to gpnmb and a blood brain barrier target and methods of use thereof
|
|
WO2025166077A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Compositions comprising progranulin and uses thereof
|
|
WO2025166045A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
β-GLUCOCEREBROSIDASE ENZYMES, FUSION PROTEINS AND COMPLEXES COMPRISING THE SAME, AND METHODS OF USE THEREOF
|
|
US12378314B1
(en)
|
2024-02-02 |
2025-08-05 |
Medicovestor, Inc. |
Proteins that bind folate receptor alpha including fully-human antibodies
|
|
US12240900B1
(en)
|
2024-02-02 |
2025-03-04 |
Medicovestor, Inc. |
Nucleic acids, vectors, and cells that encode antibodies and other proteins that bind folate receptor alpha
|
|
US12258396B1
(en)
|
2024-02-02 |
2025-03-25 |
Medicovestor, Inc. |
Methods of using immunotherapeutics that bind folate receptor alpha
|
|
WO2025174974A1
(en)
|
2024-02-14 |
2025-08-21 |
Bristol-Myers Squibb Company |
Anti-cd33 antibodies and uses thereof
|
|
WO2025172924A1
(en)
|
2024-02-15 |
2025-08-21 |
Janssen Biotech, Inc. |
Anti-transferrin receptor compositions and methods thereof
|
|
WO2025181219A1
(en)
|
2024-02-29 |
2025-09-04 |
Genmab A/S |
Egfr and c-met bispecific binding agents, conjugates thereof and methods of using the same
|
|
WO2025181189A1
(en)
|
2024-03-01 |
2025-09-04 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3
|
|
WO2025191136A1
(en)
|
2024-03-15 |
2025-09-18 |
Avidicure Ip B.V. |
Muteins of 4-1bb ligand extracellular domain, fusion proteins comprising the same and uses thereof
|
|
WO2025191144A1
(en)
|
2024-03-15 |
2025-09-18 |
Avidicure Ip B.V. |
Conjugates of egfr-specific antigen binding proteins and cytokines
|
|
WO2025191133A1
(en)
|
2024-03-15 |
2025-09-18 |
Avidicure Ip B.V. |
Il-21 muteins, fusion proteins comprising the same and uses thereof
|
|
WO2025199243A1
(en)
|
2024-03-20 |
2025-09-25 |
Regeneron Pharmaceuticals, Inc. |
Trivalent multispecific binding molecules and methods of use thereof
|
|
WO2025196639A1
(en)
|
2024-03-21 |
2025-09-25 |
Seagen Inc. |
Cd25 antibodies, antibody-drug conjugates, and uses thereof
|
|
WO2025202147A1
(en)
|
2024-03-27 |
2025-10-02 |
F. Hoffmann-La Roche Ag |
Interleukin-7 immunoconjugates
|
|
WO2025217101A2
(en)
|
2024-04-09 |
2025-10-16 |
Amgen Inc. |
Agonistic anti-il-2rbg heavy‑chain antibodies
|
|
WO2025215060A1
(en)
|
2024-04-11 |
2025-10-16 |
F. Hoffmann-La Roche Ag |
Antibodies that specifically bind modified oligonucleotides
|
|
WO2025219504A1
(en)
|
2024-04-19 |
2025-10-23 |
F. Hoffmann-La Roche Ag |
Treatment of ophthalmologic diseases
|
|
WO2025222129A2
(en)
|
2024-04-19 |
2025-10-23 |
Mozart Therapeutics, Inc. |
Engineered cytokines and targeted cytokine delivery
|
|
WO2025226808A1
(en)
|
2024-04-24 |
2025-10-30 |
Genentech, Inc. |
Compositions and methods of treating lupus nephritis
|
|
WO2025233825A1
(en)
|
2024-05-06 |
2025-11-13 |
Janssen Pharmaceutica Nv |
Enrichment of cells expressing a bird linker
|
|
WO2025233431A1
(en)
|
2024-05-07 |
2025-11-13 |
Immatics Biotechnologies Gmbh |
Heteromeric proteins comprising three heteromerization improving substitution, production, combinations and applications thereof
|
|
WO2025233304A1
(en)
|
2024-05-08 |
2025-11-13 |
F. Hoffmann-La Roche Ag |
Recombinant fc domain – il7 variant polypeptides and combination therapy with membrane-anchored antigen binding polypeptides
|
|
WO2025240335A1
(en)
|
2024-05-13 |
2025-11-20 |
Regeneron Pharmaceuticals, Inc. |
Fgfr3 binding molecules and methods of use thereof
|
|
WO2025240670A2
(en)
|
2024-05-15 |
2025-11-20 |
Abalytics Oncology, Inc. |
Anti-pd-1 antibodies and related binding molecules and methods and uses thereof
|
|
WO2025237931A1
(en)
|
2024-05-15 |
2025-11-20 |
F. Hoffmann-La Roche Ag |
Recombinant binding proteins with conditionally activatable t cell and nk cell recruiting effector domains
|
|
WO2025240781A2
(en)
|
2024-05-15 |
2025-11-20 |
Werewolf Therapeutics, Inc. |
Modified antibodies and immunoglobulin formats
|
|
WO2025238133A1
(en)
|
2024-05-17 |
2025-11-20 |
UCB Biopharma SRL |
Multispecific antibody with binding specificity for il-11 and il-17
|
|
WO2025238135A2
(en)
|
2024-05-17 |
2025-11-20 |
UCB Biopharma SRL |
Antibody with binding specificity for il-11
|
|
WO2025250969A1
(en)
|
2024-05-31 |
2025-12-04 |
Vertex Pharmaceuticals Incorporated |
Anti-cd74 antibodies, conjugates and uses thereof
|
|
WO2025255340A2
(en)
|
2024-06-05 |
2025-12-11 |
Genzyme Corporation |
BINDING PROTEINS THAT TARGET aC1s, TfR, OR BOTH, AND COMPOSITIONS THEREOF
|
|
WO2025253337A2
(en)
|
2024-06-05 |
2025-12-11 |
Sanofi |
Monospecific and bispecific tau binding proteins and compositions thereof
|
|
WO2025255349A1
(en)
|
2024-06-06 |
2025-12-11 |
Bristol-Myers Squibb Company |
Multispecific anti-cd40 / anti-fap antibodies and uses thereof
|
|
WO2025255480A1
(en)
|
2024-06-07 |
2025-12-11 |
Regeneron Pharmaceuticals, Inc. |
Tetravalent multispecific binding molecules and methods of use thereof
|
|
WO2025255452A2
(en)
|
2024-06-07 |
2025-12-11 |
Regeneron Pharmaceuticals, Inc. |
Antigen-binding molecules that bind to aav particles and uses thereof
|
|
WO2025259718A2
(en)
|
2024-06-11 |
2025-12-18 |
Regeneron Pharmaceuticals, Inc. |
Vegf antagonists and methods of use thereof
|
|
WO2025257181A1
(en)
|
2024-06-11 |
2025-12-18 |
Institut National de la Santé et de la Recherche Médicale |
Antibodies targeting trans-active response dna-binding protein-43 (tdp-43)
|
|
CN121135878A
(zh)
|
2024-06-14 |
2025-12-16 |
康诺亚生物医药科技（成都）有限公司 |
针对ox40l和il-13的双特异性抗体及其用途
|
|
WO2025259871A1
(en)
|
2024-06-14 |
2025-12-18 |
Gilead Sciences, Inc. |
Anti-ccr8 antibodies and uses thereof
|