DK1999154T3 - Fremstillede heterodimere proteindomæner - Google Patents

Fremstillede heterodimere proteindomæner

Info

Publication number
DK1999154T3
DK1999154T3 DK07723539T DK07723539T DK1999154T3 DK 1999154 T3 DK1999154 T3 DK 1999154T3 DK 07723539 T DK07723539 T DK 07723539T DK 07723539 T DK07723539 T DK 07723539T DK 1999154 T3 DK1999154 T3 DK 1999154T3
Authority
DK
Denmark
Prior art keywords
heterodimered
manufactured
protein domains
domains
protein
Prior art date
Application number
DK07723539T
Other languages
English (en)
Inventor
Jonathan H Davis
James Stafford Huston
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of DK1999154T3 publication Critical patent/DK1999154T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/246—IL-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/524—CH2 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
DK07723539T 2006-03-24 2007-03-23 Fremstillede heterodimere proteindomæner DK1999154T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78547406P 2006-03-24 2006-03-24
PCT/EP2007/002590 WO2007110205A2 (en) 2006-03-24 2007-03-23 Engineered heterodimeric protein domains

Publications (1)

Publication Number Publication Date
DK1999154T3 true DK1999154T3 (da) 2012-12-03

Family

ID=38541456

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07723539T DK1999154T3 (da) 2006-03-24 2007-03-23 Fremstillede heterodimere proteindomæner

Country Status (13)

Country Link
US (4) US8871912B2 (da)
EP (1) EP1999154B1 (da)
JP (3) JP5474531B2 (da)
AR (1) AR060070A1 (da)
AU (1) AU2007229698B9 (da)
CA (1) CA2646965C (da)
DK (1) DK1999154T3 (da)
ES (1) ES2395969T3 (da)
IL (1) IL194145A (da)
PL (1) PL1999154T3 (da)
PT (1) PT1999154E (da)
SI (1) SI1999154T1 (da)
WO (1) WO2007110205A2 (da)

Families Citing this family (519)

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