RS57840B1 - Humanizovana anti-cd 134 (ox40) antitela i njihove upotrebe - Google Patents
Humanizovana anti-cd 134 (ox40) antitela i njihove upotrebeInfo
- Publication number
- RS57840B1 RS57840B1 RS20181085A RSP20181085A RS57840B1 RS 57840 B1 RS57840 B1 RS 57840B1 RS 20181085 A RS20181085 A RS 20181085A RS P20181085 A RSP20181085 A RS P20181085A RS 57840 B1 RS57840 B1 RS 57840B1
- Authority
- RS
- Serbia
- Prior art keywords
- antibodies
- humanized anti
- humanized
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13159794 | 2013-03-18 | ||
EP14715138.5A EP2976361B1 (en) | 2013-03-18 | 2014-03-18 | Humanized anti-cd134 (ox40) antibodies and uses thereof |
PCT/NL2014/050162 WO2014148895A1 (en) | 2013-03-18 | 2014-03-18 | Humanized anti-cd134 (ox40) antibodies and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
RS57840B1 true RS57840B1 (sr) | 2018-12-31 |
Family
ID=47891522
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20181085A RS57840B1 (sr) | 2013-03-18 | 2014-03-18 | Humanizovana anti-cd 134 (ox40) antitela i njihove upotrebe |
Country Status (32)
Country | Link |
---|---|
US (3) | US9790281B2 (sr) |
EP (2) | EP2976361B1 (sr) |
JP (1) | JP2016515544A (sr) |
KR (1) | KR20160006168A (sr) |
CN (1) | CN105229032A (sr) |
AU (2) | AU2014238546C1 (sr) |
BR (1) | BR112015023862A2 (sr) |
CA (1) | CA2907436A1 (sr) |
CL (2) | CL2015002793A1 (sr) |
CR (1) | CR20150498A (sr) |
CY (1) | CY1120752T1 (sr) |
DK (1) | DK2976361T3 (sr) |
EA (1) | EA201591495A1 (sr) |
ES (1) | ES2687282T3 (sr) |
HK (1) | HK1215035A1 (sr) |
HR (1) | HRP20181478T1 (sr) |
HU (1) | HUE040234T2 (sr) |
IL (1) | IL241701A0 (sr) |
LT (1) | LT2976361T (sr) |
MD (2) | MD20180107A2 (sr) |
MX (2) | MX2015013288A (sr) |
NZ (1) | NZ712903A (sr) |
PE (1) | PE20160690A1 (sr) |
PH (1) | PH12015502185A1 (sr) |
PL (1) | PL2976361T3 (sr) |
PT (1) | PT2976361T (sr) |
RS (1) | RS57840B1 (sr) |
SG (2) | SG10201708048XA (sr) |
SI (1) | SI2976361T1 (sr) |
UA (1) | UA119319C2 (sr) |
WO (1) | WO2014148895A1 (sr) |
ZA (1) | ZA201507021B (sr) |
Families Citing this family (122)
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EP2972348B1 (en) | 2013-03-14 | 2018-08-15 | The Board of Trustees of The Leland Stanford Junior University | Methods of detecting donor-specific antibodies |
SI2976361T1 (sl) | 2013-03-18 | 2018-11-30 | Biocerox Products B.V. | Humanizirana ANTI-CD134 (OX40) protitelesa in njih uporaba |
MX2016007965A (es) | 2013-12-17 | 2016-10-28 | Genentech Inc | Terapia de combinacion que comprende agonistas de union a ox40 y antagonistas de union al eje pd-1. |
RU2016142476A (ru) | 2014-03-31 | 2018-05-07 | Дженентек, Инк. | Комбинированная терапия, включающая антиангиогенезные агенты и агонисты, связывающие ох40 |
TW201619200A (zh) | 2014-10-10 | 2016-06-01 | 麥迪紐有限責任公司 | 人類化抗-ox40抗體及其用途 |
US20160161485A1 (en) | 2014-11-03 | 2016-06-09 | Genentech, Inc. | Assays for detecting t cell immune subsets and methods of use thereof |
EP3215637B1 (en) | 2014-11-03 | 2019-07-03 | F. Hoffmann-La Roche AG | Methods and biomarkers for predicting efficacy and valuation of an ox40 agonist treatment |
AU2015343494A1 (en) | 2014-11-06 | 2017-04-27 | Genentech, Inc. | Combination therapy comprising OX40 binding agonists and TIGIT inhibitors |
RU2017121096A (ru) | 2014-11-17 | 2018-12-19 | Дженентек, Инк. | Комбинированная терапия, включающая применение ох40-связывающих агонистов и антагонистов связывания оси pd-1 |
EP4071176A3 (en) * | 2015-01-08 | 2022-12-14 | BioNTech SE | Agonistic tnf receptor binding agents |
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EP3584260A1 (en) * | 2015-04-28 | 2019-12-25 | Mitsubishi Tanabe Pharma Corporation | Rgma binding protein and use thereof |
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LT3303396T (lt) * | 2015-05-29 | 2023-01-10 | Bristol-Myers Squibb Company | Antikūnai prieš ox40 ir jų panaudojimo būdai |
US20190022092A1 (en) | 2015-09-15 | 2019-01-24 | Acerta Pharma B.V. | Therapeutic Combinations of a BTK Inhibitor and a GITR Binding Molecule, a 4-1BB Agonist, or an OX40 Agonist |
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