PT2976361T - Anticorpos anti-cd134 (ox40) humanizados e utilizações dos mesmos - Google Patents

Anticorpos anti-cd134 (ox40) humanizados e utilizações dos mesmos

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Publication number
PT2976361T
PT2976361T PT14715138T PT14715138T PT2976361T PT 2976361 T PT2976361 T PT 2976361T PT 14715138 T PT14715138 T PT 14715138T PT 14715138 T PT14715138 T PT 14715138T PT 2976361 T PT2976361 T PT 2976361T
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PT
Portugal
Prior art keywords
antibodies
humanized anti
humanized
Prior art date
Application number
PT14715138T
Other languages
English (en)
Inventor
Brezski Randall
Johannes Simons Petrus
Boon Louis
Luo Jinquan
Goldberg Monica
Original Assignee
Janssen Pharmaceuticals Inc
Biocerox Prod Bv
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47891522&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2976361(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceuticals Inc, Biocerox Prod Bv filed Critical Janssen Pharmaceuticals Inc
Publication of PT2976361T publication Critical patent/PT2976361T/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74Inducing cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75Agonist effect on antigen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
PT14715138T 2013-03-18 2014-03-18 Anticorpos anti-cd134 (ox40) humanizados e utilizações dos mesmos PT2976361T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13159794 2013-03-18

Publications (1)

Publication Number Publication Date
PT2976361T true PT2976361T (pt) 2018-10-19

Family

ID=47891522

Family Applications (1)

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PT14715138T PT2976361T (pt) 2013-03-18 2014-03-18 Anticorpos anti-cd134 (ox40) humanizados e utilizações dos mesmos

Country Status (32)

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US (3) US9790281B2 (pt)
EP (2) EP2976361B1 (pt)
JP (1) JP2016515544A (pt)
KR (1) KR20160006168A (pt)
CN (1) CN105229032A (pt)
AU (2) AU2014238546C1 (pt)
BR (1) BR112015023862A2 (pt)
CA (1) CA2907436A1 (pt)
CL (2) CL2015002793A1 (pt)
CR (1) CR20150498A (pt)
CY (1) CY1120752T1 (pt)
DK (1) DK2976361T3 (pt)
EA (1) EA201591495A1 (pt)
ES (1) ES2687282T3 (pt)
HK (1) HK1215035A1 (pt)
HR (1) HRP20181478T1 (pt)
HU (1) HUE040234T2 (pt)
IL (1) IL241701A0 (pt)
LT (1) LT2976361T (pt)
MD (2) MD20180107A2 (pt)
MX (2) MX2015013288A (pt)
NZ (1) NZ712903A (pt)
PE (1) PE20160690A1 (pt)
PH (1) PH12015502185A1 (pt)
PL (1) PL2976361T3 (pt)
PT (1) PT2976361T (pt)
RS (1) RS57840B1 (pt)
SG (2) SG10201708048XA (pt)
SI (1) SI2976361T1 (pt)
UA (1) UA119319C2 (pt)
WO (1) WO2014148895A1 (pt)
ZA (1) ZA201507021B (pt)

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