JP5620626B2 - 会合制御によるポリペプチド製造方法 - Google Patents
会合制御によるポリペプチド製造方法 Download PDFInfo
- Publication number
- JP5620626B2 JP5620626B2 JP2007511155A JP2007511155A JP5620626B2 JP 5620626 B2 JP5620626 B2 JP 5620626B2 JP 2007511155 A JP2007511155 A JP 2007511155A JP 2007511155 A JP2007511155 A JP 2007511155A JP 5620626 B2 JP5620626 B2 JP 5620626B2
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- Prior art keywords
- amino acid
- antibody
- acid residues
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005101105 | 2005-03-31 | ||
JP2005101105 | 2005-03-31 | ||
JP2005378266 | 2005-12-28 | ||
JP2005378266 | 2005-12-28 | ||
PCT/JP2006/306803 WO2006106905A1 (ja) | 2005-03-31 | 2006-03-31 | 会合制御によるポリペプチド製造方法 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012171614A Division JP5739387B2 (ja) | 2005-03-31 | 2012-08-02 | 会合制御によるポリペプチド製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2006106905A1 JPWO2006106905A1 (ja) | 2008-09-11 |
JP5620626B2 true JP5620626B2 (ja) | 2014-11-05 |
Family
ID=37073456
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007511155A Active JP5620626B2 (ja) | 2005-03-31 | 2006-03-31 | 会合制御によるポリペプチド製造方法 |
JP2012171614A Active JP5739387B2 (ja) | 2005-03-31 | 2012-08-02 | 会合制御によるポリペプチド製造方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012171614A Active JP5739387B2 (ja) | 2005-03-31 | 2012-08-02 | 会合制御によるポリペプチド製造方法 |
Country Status (12)
Country | Link |
---|---|
US (3) | US10011858B2 (es) |
EP (3) | EP3623473A1 (es) |
JP (2) | JP5620626B2 (es) |
KR (1) | KR101374454B1 (es) |
CN (1) | CN101198698B (es) |
AU (1) | AU2006232287B2 (es) |
CA (1) | CA2603408C (es) |
DK (1) | DK3050963T3 (es) |
ES (1) | ES2592271T3 (es) |
HK (1) | HK1114878A1 (es) |
TW (2) | TWI544076B (es) |
WO (1) | WO2006106905A1 (es) |
Families Citing this family (712)
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PL1876236T3 (pl) * | 2005-04-08 | 2015-01-30 | Chugai Pharmaceutical Co Ltd | Przeciwciała zastępujące czynność czynnika krzepnięcia VIII |
CN101262885B (zh) * | 2005-06-10 | 2015-04-01 | 中外制药株式会社 | 含有sc(Fv)2的药物组合物 |
CA2610987C (en) * | 2005-06-10 | 2013-09-10 | Chugai Seiyaku Kabushiki Kaisha | Stabilizer for protein preparation comprising meglumine and use thereof |
NI200800032A (es) | 2005-07-25 | 2009-03-23 | Reducción de célula b utilizando moléculas de unión específicas cd37 y cd20 | |
ES2395969T3 (es) * | 2006-03-24 | 2013-02-18 | Merck Patent Gmbh | Dominios de proteínas heterodiméricas genéticamente modificados |
US11046784B2 (en) | 2006-03-31 | 2021-06-29 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
DK2009101T3 (en) * | 2006-03-31 | 2018-01-15 | Chugai Pharmaceutical Co Ltd | Antibody modification method for purification of a bispecific antibody |
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CN101198698A (zh) | 2008-06-11 |
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US11168344B2 (en) | 2021-11-09 |
TWI544076B (zh) | 2016-08-01 |
JP5739387B2 (ja) | 2015-06-24 |
KR101374454B1 (ko) | 2014-03-17 |
EP1870459A1 (en) | 2007-12-26 |
EP1870459B1 (en) | 2016-06-29 |
HK1114878A1 (en) | 2008-11-14 |
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DK3050963T3 (da) | 2019-12-09 |
US20220267822A1 (en) | 2022-08-25 |
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EP3050963A1 (en) | 2016-08-03 |
EP3623473A1 (en) | 2020-03-18 |
CA2603408A1 (en) | 2006-10-12 |
TWI671403B (zh) | 2019-09-11 |
EP3050963B1 (en) | 2019-09-18 |
TW200722517A (en) | 2007-06-16 |
US20100015133A1 (en) | 2010-01-21 |
US20180051307A1 (en) | 2018-02-22 |
CA2603408C (en) | 2018-08-21 |
TW201631154A (zh) | 2016-09-01 |
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US10011858B2 (en) | 2018-07-03 |
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