|
US7838216B1
(en)
|
1986-03-05 |
2010-11-23 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Human gene related to but distinct from EGF receptor gene
|
|
US5869620A
(en)
*
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
|
US20050058638A1
(en)
*
|
1987-05-21 |
2005-03-17 |
Huston James S. |
Biosynthetic binding proteins for immuno-targeting
|
|
WO1990005144A1
(en)
*
|
1988-11-11 |
1990-05-17 |
Medical Research Council |
Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors
|
|
AU664030B2
(en)
*
|
1991-02-27 |
1995-11-02 |
Micromet Ag |
Serine-rich peptide linkers
|
|
AU673335B2
(en)
*
|
1991-08-05 |
1996-11-07 |
Igen, Inc. |
Prodrugs activated by targeted catalytic proteins
|
|
US6027725A
(en)
|
1991-11-25 |
2000-02-22 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
|
US20070031931A1
(en)
*
|
1992-02-06 |
2007-02-08 |
Chiron Corporation |
Biosynthetic binding proteins for immuno-targeting
|
|
EP1997894B1
(en)
*
|
1992-02-06 |
2011-03-30 |
Novartis Vaccines and Diagnostics, Inc. |
Biosynthetic binding protein for cancer marker
|
|
US7754211B2
(en)
*
|
1992-04-10 |
2010-07-13 |
Research Development Foundation |
Immunotoxins directed against c-erbB-2(HER-2/neu) related surface antigens
|
|
US20080152586A1
(en)
*
|
1992-09-25 |
2008-06-26 |
Avipep Pty Limited |
High avidity polyvalent and polyspecific reagents
|
|
WO1994012520A1
(en)
*
|
1992-11-20 |
1994-06-09 |
Enzon, Inc. |
Linker for linked fusion polypeptides
|
|
GB9225453D0
(en)
|
1992-12-04 |
1993-01-27 |
Medical Res Council |
Binding proteins
|
|
EP0672142B1
(en)
*
|
1992-12-04 |
2001-02-28 |
Medical Research Council |
Multivalent and multispecific binding proteins, their manufacture and use
|
|
DK0720624T3
(da)
|
1993-09-22 |
1999-08-09 |
Medical Res Council |
Omdirigering af antistoffer
|
|
US5753225A
(en)
*
|
1993-12-03 |
1998-05-19 |
The Regents Of The University Of California |
Antibodies that mimic actions of neurotrophins
|
|
IT1264083B1
(it)
*
|
1993-12-10 |
1996-09-10 |
Enea Ente Nuove Tec |
Procedimento per la produzione in piante di anticorpi ingegnerizzati, anticorpi prodotti e loro uso in diagnosi e terapia.
|
|
US5763733A
(en)
*
|
1994-10-13 |
1998-06-09 |
Enzon, Inc. |
Antigen-binding fusion proteins
|
|
US6514942B1
(en)
*
|
1995-03-14 |
2003-02-04 |
The Board Of Regents, The University Of Texas System |
Methods and compositions for stimulating T-lymphocytes
|
|
AUPO591797A0
(en)
*
|
1997-03-27 |
1997-04-24 |
Commonwealth Scientific And Industrial Research Organisation |
High avidity polyvalent and polyspecific reagents
|
|
US6685940B2
(en)
*
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
US5968511A
(en)
|
1996-03-27 |
1999-10-19 |
Genentech, Inc. |
ErbB3 antibodies
|
|
EP0896586B2
(en)
*
|
1996-03-27 |
2015-05-20 |
Genentech, Inc. |
ErbB3 ANTIBODIES
|
|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
|
ATE465257T1
(de)
*
|
1996-07-03 |
2010-05-15 |
Genentech Inc |
Agonisten für den rezeptor des hepatozyten- wachstumsfaktors und deren anwendungen
|
|
JP4219985B2
(ja)
*
|
1996-07-23 |
2009-02-04 |
タノックス ファーマ ベスローテン フェンノートシャップ |
二つの共刺激経路を同時にブロックできる可溶性分子を用いたt細胞寛容の誘導
|
|
AU730477B2
(en)
*
|
1996-08-05 |
2001-03-08 |
President And Fellows Of Harvard College |
MHC binding peptide oligomers and methods of use
|
|
US7371376B1
(en)
*
|
1996-10-18 |
2008-05-13 |
Genentech, Inc. |
Anti-ErbB2 antibodies
|
|
DE69841217D1
(de)
*
|
1997-01-13 |
2009-11-19 |
Univ Emory |
Glutathion zur behandlung von influenzainfektionen
|
|
WO1998033809A1
(en)
*
|
1997-01-31 |
1998-08-06 |
The General Hospital Corporation |
Compositions and methods for imaging gene expression
|
|
US20030109680A1
(en)
*
|
2001-11-21 |
2003-06-12 |
Sunol Molecular Corporation |
Antibodies for inhibiting blood coagulation and methods of use thereof
|
|
US7749498B2
(en)
*
|
1997-03-10 |
2010-07-06 |
Genentech, Inc. |
Antibodies for inhibiting blood coagulation and methods of use thereof
|
|
US5986065A
(en)
*
|
1997-03-10 |
1999-11-16 |
Sunol Molecular Corporation |
Antibodies for inhibiting blood coagulation and methods of use thereof
|
|
US20060235209A9
(en)
*
|
1997-03-10 |
2006-10-19 |
Jin-An Jiao |
Use of anti-tissue factor antibodies for treating thromboses
|
|
CA2288994C
(en)
|
1997-04-30 |
2011-07-05 |
Enzon, Inc. |
Polyalkylene oxide-modified single chain polypeptides
|
|
US20040009166A1
(en)
*
|
1997-04-30 |
2004-01-15 |
Filpula David R. |
Single chain antigen-binding polypeptides for polymer conjugation
|
|
EP0998486B2
(en)
|
1997-06-13 |
2012-02-01 |
Genentech, Inc. |
Protein recovery by chromatography followed by filtration upon a charged layer
|
|
US5994511A
(en)
|
1997-07-02 |
1999-11-30 |
Genentech, Inc. |
Anti-IgE antibodies and methods of improving polypeptides
|
|
US6172213B1
(en)
|
1997-07-02 |
2001-01-09 |
Genentech, Inc. |
Anti-IgE antibodies and method of improving polypeptides
|
|
FR2766826B1
(fr)
*
|
1997-08-04 |
2001-05-18 |
Pasteur Institut |
Vecteurs derives d'anticorps pour le transfert de substances dans les cellules
|
|
US6737249B1
(en)
*
|
1997-08-22 |
2004-05-18 |
Genentech, Inc. |
Agonist antibodies
|
|
EP1947119A3
(en)
|
1997-12-12 |
2012-12-19 |
Genentech, Inc. |
Treatment of cancer with anti-erb2 antibodies in combination with a chemotherapeutic agent
|
|
ZA9811162B
(en)
*
|
1997-12-12 |
2000-06-07 |
Genentech Inc |
Treatment with anti-ERBB2 antibodies.
|
|
EP1941905A1
(en)
|
1998-03-27 |
2008-07-09 |
Genentech, Inc. |
APO-2 Ligand-anti-her-2 antibody synergism
|
|
DE19819846B4
(de)
*
|
1998-05-05 |
2016-11-24 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Multivalente Antikörper-Konstrukte
|
|
AU4009899A
(en)
*
|
1998-05-23 |
1999-12-13 |
Tanox, Inc. |
Molecules targeting cd40 and tumor cells
|
|
GB9812545D0
(en)
*
|
1998-06-10 |
1998-08-05 |
Celltech Therapeutics Ltd |
Biological products
|
|
US6962702B2
(en)
*
|
1998-06-22 |
2005-11-08 |
Immunomedics Inc. |
Production and use of novel peptide-based agents for use with bi-specific antibodies
|
|
US7405320B2
(en)
|
1998-06-22 |
2008-07-29 |
Immunomedics, Inc. |
Therapeutic and diagnostic conjugates for use with multispecific antibodies
|
|
US7138103B2
(en)
*
|
1998-06-22 |
2006-11-21 |
Immunomedics, Inc. |
Use of bi-specific antibodies for pre-targeting diagnosis and therapy
|
|
US7833528B2
(en)
*
|
1998-06-22 |
2010-11-16 |
Immunomedics, Inc. |
Use of multispecific, non-covalent complexes for targeted delivery of therapeutics
|
|
JP4113670B2
(ja)
*
|
1998-06-22 |
2008-07-09 |
イムノメディクス, インコーポレイテッド |
プレターゲッティング診断およびプレターゲッティング治療のための二重特異性抗体の使用
|
|
US7387772B1
(en)
*
|
1999-06-22 |
2008-06-17 |
Immunimedics, Inc. |
Chimeric, human and humanized anti-CSAP monoclonal antibodies
|
|
DE19831429A1
(de)
*
|
1998-07-07 |
2000-04-27 |
Jerini Biotools Gmbh |
Verfahren zur Identifizierung und chemisch-synthetischen Nachahmung von Bindungsstellen auf Proteinen
|
|
US6228360B1
(en)
*
|
1998-08-19 |
2001-05-08 |
Ajinomoto Co., Inc. |
Antithrombotic agent and humanized anti-von Willebrand factor monoclonal antibody
|
|
US6333396B1
(en)
|
1998-10-20 |
2001-12-25 |
Enzon, Inc. |
Method for targeted delivery of nucleic acids
|
|
US7067144B2
(en)
*
|
1998-10-20 |
2006-06-27 |
Omeros Corporation |
Compositions and methods for systemic inhibition of cartilage degradation
|
|
US6818749B1
(en)
|
1998-10-31 |
2004-11-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Variants of humanized anti carcinoma monoclonal antibody cc49
|
|
WO2000029431A1
(en)
*
|
1998-11-17 |
2000-05-25 |
Tanox, Inc. |
Bispecific molecules cross-linking itim and itam for therapy
|
|
US7118743B2
(en)
|
1998-11-17 |
2006-10-10 |
Tanox, Inc. |
Bispecific molecules cross-linking ITIM and ITAM for therapy
|
|
SI1135498T1
(sl)
|
1998-11-18 |
2008-06-30 |
Genentech Inc |
Variante protitelesa z višjo vezavno afiniteto vprimerjavi z izvirnimi protitelesi
|
|
US20030086924A1
(en)
*
|
1999-06-25 |
2003-05-08 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
|
US7041292B1
(en)
|
1999-06-25 |
2006-05-09 |
Genentech, Inc. |
Treating prostate cancer with anti-ErbB2 antibodies
|
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
|
PL203326B1
(pl)
|
1999-06-25 |
2009-09-30 |
Genentech Inc |
Przeciwciało, kompozycja farmaceutyczna, koniugat, izolowany kwas nukleinowy, wektor, komórka gospodarza i sposób wytwarzania przeciwciała
|
|
US20040013667A1
(en)
*
|
1999-06-25 |
2004-01-22 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
|
KR20020012292A
(ko)
|
1999-06-25 |
2002-02-15 |
제넨테크, 인크. |
항-ErbB 항체-메이탄시노이드 결합체를 사용한 치료방법
|
|
CN100381172C
(zh)
*
|
1999-06-25 |
2008-04-16 |
吉尼泰克公司 |
使用抗-ErbB2抗体治疗前列腺癌
|
|
DE60042693D1
(de)
|
1999-08-27 |
2009-09-17 |
Genentech Inc |
Dosierung für die behandlung mit anti erbb2-antikörpern
|
|
WO2001024763A2
(en)
|
1999-10-01 |
2001-04-12 |
Immunogen, Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
|
US6794494B1
(en)
*
|
2003-04-14 |
2004-09-21 |
Arius Research, Inc. |
Cancerous disease modifying antibodies
|
|
UA74803C2
(uk)
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
|
|
EP1975182A1
(en)
|
2000-02-01 |
2008-10-01 |
PanGenetics B.V. |
CD40-binding APC-activating molecules
|
|
AU4243201A
(en)
*
|
2000-02-24 |
2001-09-03 |
Eidgenoess Tech Hochschule |
Antibody specific for the ed-b domain of fibronectin, conjugates comprising saidantibody, and their use for the detection and treatment of angiogenesis
|
|
US6319694B1
(en)
*
|
2000-03-03 |
2001-11-20 |
Genopsys, Inc. |
Random truncation and amplification of nucleic acid
|
|
US7097840B2
(en)
*
|
2000-03-16 |
2006-08-29 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
|
PT2857516T
(pt)
|
2000-04-11 |
2017-08-28 |
Genentech Inc |
Anticorpos multivalentes e utilizações dos mesmos
|
|
AU2001261024A1
(en)
|
2000-04-12 |
2001-10-30 |
Delta Biotechnology Limited |
Albumin fusion proteins
|
|
US20040180046A1
(en)
*
|
2000-04-26 |
2004-09-16 |
Jeff Himawan |
Bispecific molecules and uses thereof
|
|
AU2001259271A1
(en)
*
|
2000-04-28 |
2001-11-12 |
Millennium Pharmaceuticals, Inc. |
14094, a novel human trypsin family member and uses thereof
|
|
CN1447696A
(zh)
|
2000-05-19 |
2003-10-08 |
杰南技术公司 |
用于提高对ErbB拮抗剂癌症治疗的有效应答可能性的基因检测试验
|
|
HK1054316A1
(zh)
*
|
2000-05-26 |
2003-11-28 |
Smithkline Beecham Corporation |
用於治疗rank配体介导疾病的抗-rank配体单克隆抗体
|
|
JP2004512262A
(ja)
|
2000-06-20 |
2004-04-22 |
アイデック ファーマスーティカルズ コーポレイション |
非放射性抗cd20抗体/放射標識抗cd22抗体の組合せ
|
|
GB0027328D0
(en)
*
|
2000-06-23 |
2000-12-27 |
Aventis Pharma Inc |
Bioengineered vehicles for targeted nucleic acid delivery
|
|
CA2421783A1
(en)
*
|
2000-09-07 |
2002-03-14 |
Schering Aktiengesellschaft |
Receptor in the edb fibronectin domain
|
|
US6631283B2
(en)
*
|
2000-11-15 |
2003-10-07 |
Virginia Tech Intellectual Properties, Inc. |
B/B-like fragment targeting for the purposes of photodynamic therapy and medical imaging
|
|
MA26040A1
(fr)
|
2001-01-05 |
2004-04-01 |
Pfizer |
Des anticorps pour recepteur i de facteur de croissance insulinique
|
|
US20020159996A1
(en)
|
2001-01-31 |
2002-10-31 |
Kandasamy Hariharan |
Use of CD23 antagonists for the treatment of neoplastic disorders
|
|
EP1381384B1
(en)
|
2001-04-24 |
2011-05-25 |
Merck Patent GmbH |
COMBINATION THERAPY USING ANTI-ANGIOGENIC AGENTS AND TNFalpha
|
|
CN1195779C
(zh)
|
2001-05-24 |
2005-04-06 |
中国科学院遗传与发育生物学研究所 |
抗人卵巢癌抗人cd3双特异性抗体
|
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
|
KR100788092B1
(ko)
|
2001-06-20 |
2007-12-21 |
제넨테크, 인크. |
종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물
|
|
AU2002345792A1
(en)
|
2001-06-21 |
2003-01-08 |
Pfizer Inc. |
Thienopyridine and thienopyrimidine anticancer agents
|
|
MXPA04002593A
(es)
|
2001-09-18 |
2004-05-31 |
Genentech Inc |
Composiciones y metodos para el diagnostico y tratamiento de tumor.
|
|
US20050123925A1
(en)
|
2002-11-15 |
2005-06-09 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
AR039067A1
(es)
*
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
KR100623128B1
(ko)
|
2002-01-02 |
2006-09-14 |
제넨테크, 인크. |
종양의 진단 및 치료 방법 및 이를 위한 조성물
|
|
EP2239274A1
(en)
*
|
2002-01-03 |
2010-10-13 |
Bayer Schering Pharma AG |
New methods for diagnosis and treatment of tumours
|
|
AU2003210802B2
(en)
|
2002-02-05 |
2009-09-10 |
Genentech Inc. |
Protein purification
|
|
US6869787B2
(en)
*
|
2002-02-27 |
2005-03-22 |
The United States Of America As Represented By The Secretary Of The Army |
Ricin vaccine and methods of making and using thereof
|
|
ES2401428T3
(es)
|
2002-04-10 |
2013-04-19 |
Genentech, Inc. |
Variantes de anticuerpos anti-HER2
|
|
PL375033A1
(en)
*
|
2002-04-11 |
2005-11-14 |
Amgen, Inc. |
Her-2 receptor tyrosine kinase molecules and uses thereof
|
|
KR20040101502A
(ko)
|
2002-04-16 |
2004-12-02 |
제넨테크, 인크. |
종양의 진단 및 치료 방법 및 이를 위한 조성물
|
|
UA77303C2
(en)
*
|
2002-06-14 |
2006-11-15 |
Pfizer |
Derivatives of thienopyridines substituted by benzocondensed heteroarylamide useful as therapeutic agents, pharmaceutical compositions and methods for their use
|
|
US7569673B2
(en)
*
|
2002-06-28 |
2009-08-04 |
The United States Of America As Represented By The Department Of Health And Human Services |
Humanized anti-tag 72 cc49 for diagnosis and therapy of human tumors
|
|
ATE535254T1
(de)
|
2002-07-15 |
2011-12-15 |
Genentech Inc |
Behandlung von krebs mit dem anti-erbb2- antikörper rhumab 2c4
|
|
JP5303092B2
(ja)
|
2002-09-11 |
2013-10-02 |
ジェネンテック, インコーポレイテッド |
タンパク質精製
|
|
AU2002951853A0
(en)
*
|
2002-10-04 |
2002-10-24 |
Commonwealth Scientific And Industrial Research Organisation |
Crystal structure of erbb2 and uses thereof
|
|
US9701754B1
(en)
|
2002-10-23 |
2017-07-11 |
City Of Hope |
Covalent disulfide-linked diabodies and uses thereof
|
|
WO2004048525A2
(en)
*
|
2002-11-21 |
2004-06-10 |
Genentech, Inc. |
Therapy of non-malignant diseases or disorders with anti-erbb2 antibodies
|
|
US20040186160A1
(en)
*
|
2002-12-13 |
2004-09-23 |
Sugen, Inc. |
Hexahydro-cyclohepta-pyrrole oxindole as potent kinase inhibitors
|
|
BR0317548A
(pt)
*
|
2002-12-19 |
2005-11-22 |
Pfizer |
Compostos de indazole e composições farmacêuticas para a inibição de proteìnas-cinases e métodos para o seu uso
|
|
EP1592777A4
(en)
|
2003-02-01 |
2008-06-04 |
Tanox Inc |
METHOD OF GENERATING HIGH-ANTIBODY ANTIBODIES
|
|
WO2004076412A2
(en)
|
2003-02-26 |
2004-09-10 |
Sugen, Inc. |
Aminoheteroaryl compounds as protein kinase inhibitors
|
|
WO2004087152A1
(en)
*
|
2003-04-03 |
2004-10-14 |
Pfizer Inc. |
Dosage forms comprising ag013736
|
|
HRP20050934B1
(hr)
|
2003-04-04 |
2014-09-26 |
Genentech, Inc. |
Formulacije s visokom koncentracijom antitijela i proteina
|
|
MXPA05010778A
(es)
|
2003-04-09 |
2005-12-12 |
Genentech Inc |
Terapia para enfermedad autoinmune en un paciente con una respuesta inadecuada a un inhibidor tnf-alfa.
|
|
US7425328B2
(en)
*
|
2003-04-22 |
2008-09-16 |
Purdue Pharma L.P. |
Tissue factor antibodies and uses thereof
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
RS20150135A1
(sr)
|
2003-05-30 |
2015-08-31 |
Genentech Inc. |
Tretman sa anti-vegf antitelima
|
|
NZ543712A
(en)
|
2003-06-05 |
2008-06-30 |
Genentech Inc |
Combination therapy for B cell disorders
|
|
WO2005004793A2
(en)
*
|
2003-06-19 |
2005-01-20 |
Tanox Inc. |
Compositions and methods for treating coagulation related disorders
|
|
MX341074B
(es)
|
2003-07-08 |
2016-08-05 |
Genentech Inc |
Polipeptidos heterologos il-17 a/f y usos terapeuticos de los mismos.
|
|
EP3095793B1
(en)
|
2003-07-28 |
2020-03-25 |
Genentech, Inc. |
Reducing protein a leaching during protein a affinity chromatography
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
WO2005021594A2
(en)
*
|
2003-08-29 |
2005-03-10 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Minimally immunogenic variants of sdr-grafted humanized antibody cc49 and their use
|
|
BRPI0413876A
(pt)
*
|
2003-08-29 |
2006-10-24 |
Pfizer |
tienopiridin-fenilacetamidas e seus derivados úteis como agentes antiangiogênicos
|
|
BRPI0414011A
(pt)
*
|
2003-08-29 |
2006-10-24 |
Pfizer |
naftalencarboxamidas e seus derivados úteis como novos agentes antiangiogênicos
|
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
CN104998273A
(zh)
|
2003-11-06 |
2015-10-28 |
西雅图基因公司 |
能够与配体偶联的单甲基缬氨酸化合物
|
|
DE602004024921D1
(de)
|
2003-11-17 |
2010-02-11 |
Genentech Inc |
Zusammensetzungen und verfahren zur behandlung von tumoren hämatopoetischen ursprungs
|
|
DK1689721T3
(da)
*
|
2003-11-26 |
2010-09-20 |
Pfizer Prod Inc |
Aminopyrazolderivater som GSK-3-ihibitorer
|
|
US8298532B2
(en)
|
2004-01-16 |
2012-10-30 |
Regeneron Pharmaceuticals, Inc. |
Fusion polypeptides capable of activating receptors
|
|
DE602005018325D1
(de)
|
2004-02-19 |
2010-01-28 |
Genentech Inc |
Antikörper mit korrigierten cdr
|
|
CA2561516A1
(en)
*
|
2004-03-30 |
2005-10-13 |
Pfizer Products Inc. |
Combinations of signal transduction inhibitors
|
|
WO2005097832A2
(en)
|
2004-03-31 |
2005-10-20 |
Genentech, Inc. |
Humanized anti-tgf-beta antibodies
|
|
US20150017671A1
(en)
|
2004-04-16 |
2015-01-15 |
Yaping Shou |
Methods for detecting lp-pla2 activity and inhibition of lp-pla2 activity
|
|
CA2567520A1
(en)
|
2004-06-01 |
2005-12-15 |
Genentech, Inc. |
Maytansinoid-antibody conjugates
|
|
AU2005249566B2
(en)
|
2004-06-04 |
2010-11-11 |
Genentech, Inc. |
Method for treating multiple sclerosis
|
|
GT200500155A
(es)
|
2004-06-16 |
2006-05-15 |
|
Terapia del càncer resistente al platino
|
|
MX2007000610A
(es)
*
|
2004-07-16 |
2007-03-07 |
Pfizer Prod Inc |
Tratamiento de combinacion para enfermedades malignas no hematologicas usando un anti-cuerpo de receptor de factor i de crecimiento de tipo anti-insulina.
|
|
US8604185B2
(en)
|
2004-07-20 |
2013-12-10 |
Genentech, Inc. |
Inhibitors of angiopoietin-like 4 protein, combinations, and their use
|
|
SI1771474T1
(sl)
|
2004-07-20 |
2010-06-30 |
Genentech Inc |
Inhibitorji angiopoetinu podobnega proteina kombinacije in njihova uporaba
|
|
BRPI0513915A
(pt)
*
|
2004-08-26 |
2008-05-20 |
Pfizer |
compostos aminoeteroarila enantiomericamente puros como inibidores de proteìna quinase
|
|
MX2007001986A
(es)
*
|
2004-08-26 |
2007-05-10 |
Pfizer |
Compuestos de aminoheteroarilo como inhibidores de proteina quinasa.
|
|
ATE492544T1
(de)
*
|
2004-08-26 |
2011-01-15 |
Pfizer |
Pyrazol-substituierte aminoheteroarylverbindungen als proteinkinasehemmer
|
|
WO2006034335A2
(en)
*
|
2004-09-21 |
2006-03-30 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Method of detecting cancer based on immune reaction to boris
|
|
EP3088004B1
(en)
|
2004-09-23 |
2018-03-28 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
US20060107555A1
(en)
*
|
2004-11-09 |
2006-05-25 |
Curtis Marc D |
Universal snow plow adapter
|
|
DK1841793T3
(da)
|
2005-01-07 |
2010-07-19 |
Diadexus Inc |
Ovr110-antistofsammensætninger og fremgangsmåder til anvendelse deraf
|
|
CN102580084B
(zh)
|
2005-01-21 |
2016-11-23 |
健泰科生物技术公司 |
Her抗体的固定剂量给药
|
|
EP1846558A2
(en)
*
|
2005-02-09 |
2007-10-24 |
Genentech, Inc. |
Inhibiting her2 shedding with matrix metalloprotease antagonists
|
|
KR101289537B1
(ko)
|
2005-02-15 |
2013-07-31 |
듀크 유니버시티 |
항-cd19 항체 및 종양학에서 이의 용도
|
|
MX2007009889A
(es)
|
2005-02-23 |
2007-09-07 |
Genentech Inc |
Alargar el tiempo hasta la progresion de la enfermedad o la supervivencia de los pacientes de cancer.
|
|
TW200642695A
(en)
*
|
2005-03-08 |
2006-12-16 |
Genentech Inc |
Methods for identifying tumors responsive to treatment with her dimerization inhibitors (HDIs)
|
|
AU2006230563B8
(en)
|
2005-03-31 |
2010-06-17 |
Agensys, Inc. |
Antibodies and related molecules that bind to 161P2F10B proteins
|
|
CA2763671A1
(en)
|
2005-04-26 |
2006-11-02 |
Pfizer Inc. |
P-cadherin antibodies
|
|
EP1885755A4
(en)
|
2005-05-05 |
2009-07-29 |
Univ Duke |
CD19 ANTIBODY THERAPY FOR AUTOIMMUNE DISEASES
|
|
JP2006316040A
(ja)
|
2005-05-13 |
2006-11-24 |
Genentech Inc |
Herceptin(登録商標)補助療法
|
|
AU2006255686A1
(en)
|
2005-06-06 |
2006-12-14 |
Genentech, Inc. |
Transgenic models for different genes and their use for gene characterization
|
|
CA2614436C
(en)
|
2005-07-07 |
2016-05-17 |
Seattle Genetics, Inc. |
Monomethylvaline compounds having phenylalanine side-chain modifications at the c-terminus
|
|
EP1922410A2
(en)
|
2005-08-15 |
2008-05-21 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
|
MY164457A
(en)
|
2005-09-07 |
2017-12-15 |
Amgen Fremont Inc |
Human monoclonal antibodies to activin receptor-like kinase-1
|
|
ATE533057T1
(de)
|
2005-09-20 |
2011-11-15 |
Osi Pharm Inc |
Biologische marker als prädiktoren der antikrebsreaktion auf insulinähnlichen wachstumsfaktor-1-rezeptor-kinaseinhibitoren
|
|
KR20180002911A
(ko)
|
2005-11-04 |
2018-01-08 |
제넨테크, 인크. |
안질환 치료를 위한 보체 경로 억제제의 용도
|
|
MY149159A
(en)
|
2005-11-15 |
2013-07-31 |
Hoffmann La Roche |
Method for treating joint damage
|
|
JP2009516514A
(ja)
|
2005-11-21 |
2009-04-23 |
ジェネンテック・インコーポレーテッド |
新規遺伝子破壊、それらに関する組成物および方法
|
|
EP1954719A2
(en)
|
2005-12-02 |
2008-08-13 |
Genentech Inc. |
Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r
|
|
ES2535856T3
(es)
|
2005-12-15 |
2015-05-18 |
Genentech, Inc. |
Métodos y composiciones para dirigirse a la poliubiquitina
|
|
US7625759B2
(en)
|
2005-12-19 |
2009-12-01 |
Genentech, Inc. |
Method for using BOC/CDO to modulate hedgehog signaling
|
|
JP5164856B2
(ja)
|
2006-01-05 |
2013-03-21 |
ジェネンテック, インコーポレイテッド |
抗ephb4抗体およびその使用方法
|
|
CN101370831B
(zh)
*
|
2006-01-13 |
2013-06-19 |
Irm责任有限公司 |
用于治疗过敏性疾病的针对胸腺基质淋巴细胞生成素受体的抗体
|
|
ES2521679T3
(es)
|
2006-01-18 |
2014-11-13 |
Merck Patent Gmbh |
Terapia específica usando ligandos de integrinas para el tratamiento del cáncer
|
|
EP1988768A2
(en)
|
2006-02-17 |
2008-11-12 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
|
EP2540741A1
(en)
|
2006-03-06 |
2013-01-02 |
Aeres Biomedical Limited |
Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
AR059851A1
(es)
|
2006-03-16 |
2008-04-30 |
Genentech Inc |
Anticuerpos de la egfl7 y metodos de uso
|
|
CA2646329C
(en)
|
2006-03-20 |
2018-07-03 |
The Regents Of The University Of California |
Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting
|
|
WO2007109376A2
(en)
|
2006-03-23 |
2007-09-27 |
Novartis Ag |
Anti-tumor cell antigen antibody therapeutics
|
|
CA2647277A1
(en)
|
2006-04-05 |
2007-11-08 |
Genentech, Inc. |
Method for using boc/cdo to modulate hedgehog signaling
|
|
EP2082645A1
(en)
|
2006-04-19 |
2009-07-29 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
|
EP2258700A1
(en)
|
2006-05-09 |
2010-12-08 |
Pfizer Products Inc. |
Cycloalkylamino acid derivatives and pharmaceutical compositions thereof
|
|
NL2000613C2
(nl)
|
2006-05-11 |
2007-11-20 |
Pfizer Prod Inc |
Triazoolpyrazinederivaten.
|
|
US8524865B2
(en)
|
2006-05-30 |
2013-09-03 |
Genentech, Inc. |
Antibodies and immunoconjugates and uses therefor
|
|
NZ573819A
(en)
|
2006-06-02 |
2011-09-30 |
Aveo Pharmaceuticals Inc |
Hepatocyte growth factor (hgf) binding proteins
|
|
BRPI0712222B1
(pt)
|
2006-06-02 |
2021-10-13 |
Aveo Pharmaceuticals, Inc. |
Proteína de ligação isolada que se liga ao fator de crescimento de hepatócito humano (hgf), seu uso e método de produção, ácido nucléico, vetor de expressão, célula hospedeira, e métodos para produzir um polipeptídeo que compreende uma região variável da cadeia pesada de imunoglobulina e para produzir um polipeptídeo que compreende uma região variável da cadeia leve de imunoglobulina
|
|
FR2902799B1
(fr)
|
2006-06-27 |
2012-10-26 |
Millipore Corp |
Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
|
|
MX2008015830A
(es)
|
2006-06-30 |
2009-01-09 |
Novo Nordisk As |
Anticuerpos anti-nkg2a y usos de los mismos.
|
|
AU2007275654A1
(en)
|
2006-07-19 |
2008-01-24 |
The Trustees Of The University Of Pennsylvania |
WSX-1/p28 as a target for anti-inflammatory responses
|
|
US7862813B2
(en)
|
2006-07-29 |
2011-01-04 |
Bjork Jr Robert Lamar |
Bi-specific monoclonal antibody (specific for both CD3 and CD11b) therapeutic drug
|
|
CA2660286A1
(en)
|
2006-08-09 |
2008-02-21 |
Homestead Clinical Corporation |
Organ-specific proteins and methods of their use
|
|
EP2061900A2
(en)
|
2006-08-25 |
2009-05-27 |
Oncotherapy Science, Inc. |
Prognostic markers and therapeutic targets for lung cancer
|
|
MX2009002414A
(es)
|
2006-09-08 |
2009-05-20 |
Medimmune Llc |
Anticuerpos anti-cd19 humanizados y su uso en el tratamiento de oncologia, transplante y enfermedad autoinmunitaria.
|
|
EP2469283B1
(en)
|
2006-09-08 |
2014-01-15 |
The Chancellor, Masters and Scholars of the University of Oxford |
Clinical diagnosis of hepatic fibrosis using human serum APOL1 as biomarker
|
|
US20080076139A1
(en)
|
2006-09-21 |
2008-03-27 |
Sharat Singh |
Methods and compositions for detecting the activation states of multiple signal transducers in rare circulating cells
|
|
MX2009003938A
(es)
|
2006-10-27 |
2009-04-24 |
Genentech Inc |
Anticuerpos e inmunoconjugados y sus usos.
|
|
ES2437110T3
(es)
|
2006-11-14 |
2014-01-08 |
Genentech, Inc. |
Moduladores de la regeneración neuronal
|
|
CA2670471A1
(en)
|
2006-11-22 |
2008-06-05 |
Adnexus, A Bristol-Myers Squibb R&D Company (A Delaware Corporation) |
Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir
|
|
CA2670696A1
(en)
|
2006-11-27 |
2008-06-05 |
Diadexus, Inc. |
Ovr110 antibody compositions and methods of use
|
|
KR101568049B1
(ko)
|
2006-12-18 |
2015-11-11 |
제넨테크, 인크. |
항-notch3 길항제 항체 및 notch3-관련 질환의 예방 및 치료에 있어서 그의 용도
|
|
US8362217B2
(en)
|
2006-12-21 |
2013-01-29 |
Emd Millipore Corporation |
Purification of proteins
|
|
US8569464B2
(en)
|
2006-12-21 |
2013-10-29 |
Emd Millipore Corporation |
Purification of proteins
|
|
WO2008079302A2
(en)
|
2006-12-21 |
2008-07-03 |
Millipore Corporation |
Purification of proteins
|
|
JP2010513321A
(ja)
*
|
2006-12-22 |
2010-04-30 |
ノヴェリクス・セラピューティクス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
少なくとも一種の上皮細胞増殖因子受容体特異抗体またはその誘導体を用いる糖尿病の治療
|
|
WO2008087025A2
(en)
|
2007-01-18 |
2008-07-24 |
Merck Patent Gmbh |
Specific therapy and medicament using integrin ligands for treating cancer
|
|
MX2009008430A
(es)
|
2007-02-09 |
2009-10-28 |
Genentech Inc |
Anticuerpos anti-robo4 y sus usos.
|
|
JP5761915B2
(ja)
|
2007-02-22 |
2015-08-12 |
ジェネンテック, インコーポレイテッド |
炎症性腸疾患の検出方法
|
|
ES2477497T3
(es)
|
2007-03-02 |
2014-07-17 |
Genentech, Inc. |
Predicción de la respuesta a un inhibidor de la dimerización de HER basado en la expresión de HER3 bajo
|
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
|
ES2529790T3
(es)
|
2007-04-13 |
2015-02-25 |
Dana-Farber Cancer Institute, Inc. |
Métodos de tratamiento de cáncer resistente a agentes terapéuticos de ERBB
|
|
EP2703011A3
(en)
|
2007-05-07 |
2014-03-26 |
MedImmune, LLC |
Anti-icos antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
US20090163698A1
(en)
*
|
2007-05-11 |
2009-06-25 |
John Joseph Grigsby |
Method for Preparing Antibody Conjugates
|
|
US9551033B2
(en)
|
2007-06-08 |
2017-01-24 |
Genentech, Inc. |
Gene expression markers of tumor resistance to HER2 inhibitor treatment
|
|
CA3006428A1
(en)
|
2007-06-08 |
2008-12-18 |
Genentech, Inc. |
Gene expression markers of tumor resistance to her2 inhibitor treatment
|
|
HUE046992T2
(hu)
|
2007-07-09 |
2020-04-28 |
Genentech Inc |
Diszulfidkötés redukciójának megelõzése polipeptidek rekombináns elõállítása során
|
|
ES2528922T3
(es)
|
2007-07-16 |
2015-02-13 |
Genentech, Inc. |
Anticuerpos anti-CD79b humanizados e inmunoconjugados y métodos de uso
|
|
RS53595B1
(sr)
|
2007-07-16 |
2015-02-27 |
Genentech, Inc. |
Anti-cd79b antitela i imunokonjugati i metode upotrebe
|
|
WO2009028580A1
(en)
|
2007-08-24 |
2009-03-05 |
Oncotherapy Science, Inc. |
Ebi3, dlx5, nptx1 and cdkn3 for target genes of lung cancer therapy and diagnosis
|
|
US8709731B2
(en)
|
2007-08-24 |
2014-04-29 |
Oncotherapy Science, Inc. |
DKK1 oncogene as therapeutic target for cancer and a diagnosing marker
|
|
TW200920405A
(en)
|
2007-08-24 |
2009-05-16 |
Oncotherapy Science Inc |
PKIB and NAALADL2 for target genes of prostate cancer therapy and diagnosis
|
|
MY159201A
(en)
|
2007-08-29 |
2016-12-30 |
Sanofi Aventis |
Humanized anti-cxcr5 antibodies, derivatives thereof and their uses
|
|
CA2698343C
(en)
|
2007-09-04 |
2018-06-12 |
The Regents Of The University Of California |
High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection
|
|
PT2185574E
(pt)
|
2007-09-07 |
2013-08-26 |
Agensys Inc |
Anticorpos e moléculas relacionadas que se ligam a proteínas 24p4c12
|
|
RU2526512C2
(ru)
|
2007-09-26 |
2014-08-20 |
Чугаи Сейяку Кабусики Кайся |
Модифицированная константная область антитела
|
|
US8691222B2
(en)
|
2007-10-02 |
2014-04-08 |
Genentech, Inc. |
NLRR-1 antagonists and uses thereof
|
|
EP2050764A1
(en)
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
|
EP2200631A1
(en)
|
2007-10-16 |
2010-06-30 |
Zymogenetics, Inc. |
Combination of blys inhibition and anti-cd 20 agents for treatment of autoimmune disease
|
|
US20090148435A1
(en)
|
2007-10-30 |
2009-06-11 |
Genentech, Inc. |
Antibody purification by cation exchange chromatography
|
|
WO2009062102A2
(en)
|
2007-11-07 |
2009-05-14 |
Genentech, Inc. |
Compositions and methods for treatment of microbial disorders
|
|
WO2010135521A2
(en)
|
2009-05-20 |
2010-11-25 |
Theraclone Sciences, Inc. |
Compositions and methods for the therapy and diagnosis of influenza
|
|
MX2010005244A
(es)
|
2007-11-12 |
2010-10-25 |
Theraclone Sciences Inc |
Composiciones y métodos para la terapia y el diagnóstico de influenza.
|
|
CN101970689A
(zh)
|
2007-11-29 |
2011-02-09 |
健泰科生物技术公司 |
炎性肠病的基因表达标志物
|
|
TWI580694B
(zh)
|
2007-11-30 |
2017-05-01 |
建南德克公司 |
抗-vegf抗體
|
|
KR101615935B1
(ko)
|
2007-12-14 |
2016-04-28 |
노보 노르디스크 에이/에스 |
인간 nkg2d에 대한 항체 및 그것의 용도
|
|
EP2235536A4
(en)
|
2007-12-20 |
2011-05-04 |
Lab Corp America Holdings |
HER-2-DIAGNOSTIC PROCEDURE
|
|
US8253725B2
(en)
*
|
2007-12-28 |
2012-08-28 |
St. Jude Medical, Atrial Fibrillation Division, Inc. |
Method and system for generating surface models of geometric structures
|
|
EP2077281A1
(en)
|
2008-01-02 |
2009-07-08 |
Bergen Teknologioverforing AS |
Anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome
|
|
US7914785B2
(en)
|
2008-01-02 |
2011-03-29 |
Bergen Teknologieverforing As |
B-cell depleting agents, like anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome
|
|
AR070141A1
(es)
|
2008-01-23 |
2010-03-17 |
Glenmark Pharmaceuticals Sa |
Anticuerpos humanizados especificos para el factor von willebrand
|
|
JP5774312B2
(ja)
|
2008-01-24 |
2015-09-09 |
ノボ・ノルデイスク・エー/エス |
ヒト化抗ヒトnkg2aモノクローナル抗体
|
|
EP2238162A1
(en)
*
|
2008-01-24 |
2010-10-13 |
The Government of the United States of America as represented by The Secretary of the Department of Health and Human Services |
Induced internalization of surface receptors
|
|
TWI472339B
(zh)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至her2結構域ii之抗體及其酸性變異體的組合物
|
|
IL287292B
(en)
|
2008-01-31 |
2022-09-01 |
Genentech Inc |
Cycteine engineering anti-cd79b antibodies and antibody-drug conjugates
|
|
JP2011517314A
(ja)
|
2008-02-14 |
2011-06-02 |
ブリストル−マイヤーズ スクイブ カンパニー |
Egfrに結合する操作されたタンパク質に基づく標的化された治療薬
|
|
NZ617520A
(en)
|
2008-02-25 |
2015-05-29 |
Nestec Sa |
Drug selection for breast cancer therapy using antibody-based arrays
|
|
EP2257571B1
(en)
|
2008-03-10 |
2015-03-04 |
Theraclone Sciences, Inc. |
Compositions and methods for the therapy and diagnosis of cytomegalovirus infections
|
|
US8663643B2
(en)
|
2008-03-18 |
2014-03-04 |
Genentech, Inc. |
Combinations of an anti-HER2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
|
|
ES2354661B1
(es)
|
2008-05-08 |
2012-02-01 |
Consejo Superior De Investigaciones Científicas (Csic) |
Método para generar anticuerpos monoclonales que reconocen antígenos de membrana de células progenitoras neurales, anticuerpos producidos por dicho método, y usos.
|
|
US8093018B2
(en)
|
2008-05-20 |
2012-01-10 |
Otsuka Pharmaceutical Co., Ltd. |
Antibody identifying an antigen-bound antibody and an antigen-unbound antibody, and method for preparing the same
|
|
CN102099373A
(zh)
|
2008-05-22 |
2011-06-15 |
百时美施贵宝公司 |
基于纤连蛋白的多价支架结构域蛋白
|
|
US8999702B2
(en)
|
2008-06-11 |
2015-04-07 |
Emd Millipore Corporation |
Stirred tank bioreactor
|
|
BRPI0812682A2
(pt)
|
2008-06-16 |
2010-06-22 |
Genentech Inc |
tratamento de cáncer de mama metastático
|
|
EP2318832B1
(en)
|
2008-07-15 |
2013-10-09 |
Academia Sinica |
Glycan arrays on ptfe-like aluminum coated glass slides and related methods
|
|
US20100029675A1
(en)
*
|
2008-07-25 |
2010-02-04 |
Hwang Soo-In |
Pyrimidine-2, 4-diamine JAK2 Kinase inhibiting anti-inflammation use
|
|
DK2848625T3
(da)
|
2008-08-14 |
2019-10-07 |
Genentech Inc |
Fremgangsmåder til fjernelse af en kontaminant under anvendelse af ion bytningsmembrankromatografi med forskydning af naturligt forekommende proteiner
|
|
RU2478648C2
(ru)
|
2008-09-07 |
2013-04-10 |
Гликонекс Инк. |
Антитело против удлиненного гликосфинголипида i типа, его производные и применение
|
|
TW201438738A
(zh)
|
2008-09-16 |
2014-10-16 |
Genentech Inc |
治療進展型多發性硬化症之方法
|
|
US8476410B2
(en)
|
2008-10-16 |
2013-07-02 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Fully human antibodies to high molecular weight-melanoma associated antigen and uses thereof
|
|
CA2741089A1
(en)
|
2008-10-22 |
2010-04-29 |
Genentech, Inc. |
Modulation of axon degeneration
|
|
CN102753193A
(zh)
|
2008-10-31 |
2012-10-24 |
比奥根艾迪克Ma公司 |
Light靶向分子及其用途
|
|
CN102438652B
(zh)
|
2008-11-12 |
2014-08-13 |
米迪缪尼有限公司 |
抗体制剂
|
|
CA3019967A1
(en)
|
2008-11-13 |
2010-05-20 |
The General Hospital Corporation |
Methods and compositions for regulating iron homeostasis by modulation of bmp-6
|
|
JP5677972B2
(ja)
*
|
2008-11-18 |
2015-02-25 |
メリマック ファーマシューティカルズ インコーポレーティッド |
ヒト血清アルブミンリンカーおよびそのコンジュゲート
|
|
US20100143351A1
(en)
|
2008-11-22 |
2010-06-10 |
Genentech, Inc. |
Anti-Angiogenesis Therapy for the Treatment of Breast Cancer
|
|
US8211434B2
(en)
|
2008-11-26 |
2012-07-03 |
Allergan, Inc. |
KLK-13 antibody inhibitor for treating dry eye
|
|
ES2637411T3
(es)
|
2008-12-01 |
2017-10-13 |
Laboratory Corporation Of America Holdings |
Métodos y ensayos para medir p95 Y/O p95 en una muestra y anticuerpos específicos para p95
|
|
US8217149B2
(en)
|
2008-12-09 |
2012-07-10 |
Genentech, Inc. |
Anti-PD-L1 antibodies, compositions and articles of manufacture
|
|
SG171446A1
(en)
|
2008-12-16 |
2011-07-28 |
Millipore Corp |
Stirred tank reactor and method
|
|
US20110020327A1
(en)
|
2008-12-16 |
2011-01-27 |
Millipore Corporation |
Purification of proteins
|
|
AU2009335788A1
(en)
|
2008-12-17 |
2011-07-07 |
Genentech, Inc. |
Hepatitis C virus combination therapy
|
|
WO2010075249A2
(en)
|
2008-12-22 |
2010-07-01 |
Genentech, Inc. |
A method for treating rheumatoid arthritis with b-cell antagonists
|
|
JP5746051B2
(ja)
|
2009-01-15 |
2015-07-08 |
ラボラトリー コーポレイション オブ アメリカ ホールディングス |
Her−3の測定による患者の反応を判定する方法
|
|
CN102307875A
(zh)
|
2009-02-09 |
2012-01-04 |
苏伯俭股份有限公司 |
吡咯并嘧啶基axl激酶抑制剂
|
|
US10517969B2
(en)
|
2009-02-17 |
2019-12-31 |
Cornell University |
Methods and kits for diagnosis of cancer and prediction of therapeutic value
|
|
EP2398829A2
(en)
|
2009-02-23 |
2011-12-28 |
Glenmark Pharmaceuticals S.A. |
Humanized antibodies that bind to cd19 and their uses
|
|
EP2400985A2
(en)
|
2009-02-25 |
2012-01-04 |
OSI Pharmaceuticals, LLC |
Combination of an either an anti-igf-1r antibody or an igf binding protein and a small molecule igf-1r kinase inhibitor
|
|
JP2012519170A
(ja)
|
2009-02-26 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
生体内の腫瘍細胞のemtステータスをモニターするためのinsitu法
|
|
JP2012519281A
(ja)
|
2009-02-27 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
間葉様腫瘍細胞またはその生成を阻害する薬剤を同定するための方法
|
|
WO2010099364A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
TW201035088A
(en)
|
2009-02-27 |
2010-10-01 |
Supergen Inc |
Cyclopentathiophene/cyclohexathiophene DNA methyltransferase inhibitors
|
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
EP2409155A1
(en)
|
2009-03-15 |
2012-01-25 |
Technion Research and Development Foundation, Ltd. |
Soluble hla complexes for use in disease diagnosis
|
|
SI3260136T1
(sl)
|
2009-03-17 |
2021-05-31 |
Theraclone Sciences, Inc. |
Humani imunodeficientni virus (HIV)-nevtralizirajoča protitelesa
|
|
AR075896A1
(es)
|
2009-03-20 |
2011-05-04 |
Genentech Inc |
Anticuerpos anti-her (factor de crecimiento epidermico)
|
|
SG174904A1
(en)
|
2009-03-25 |
2011-11-28 |
Genentech Inc |
Anti-fgfr3 antibodies and methods using same
|
|
WO2010114859A1
(en)
|
2009-04-01 |
2010-10-07 |
Genentech, Inc. |
Treatment of insulin-resistant disorders
|
|
WO2010120561A1
(en)
|
2009-04-01 |
2010-10-21 |
Genentech, Inc. |
Anti-fcrh5 antibodies and immunoconjugates and methods of use
|
|
SI2417156T1
(sl)
|
2009-04-07 |
2015-06-30 |
Roche Glycart Ag |
Trivalentna, bispecifiäśna protitelesa
|
|
WO2010118243A2
(en)
|
2009-04-08 |
2010-10-14 |
Genentech, Inc. |
Use of il-27 antagonists to treat lupus
|
|
US8753631B2
(en)
*
|
2009-05-01 |
2014-06-17 |
New York University |
Therapeutic agents for inducing platelet fragmentation and treating thromboembolic disorders
|
|
EP2799876B1
(en)
|
2009-05-14 |
2021-11-03 |
ShOx Science Limited |
Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers
|
|
NZ597339A
(en)
|
2009-05-25 |
2013-10-25 |
Merck Patent Gmbh |
Continuous administration of cilengitide in cancer treatments
|
|
SG176073A1
(en)
|
2009-05-29 |
2011-12-29 |
Hoffmann La Roche |
Modulators for her2 signaling in her2 expressing patients with gastric cancer
|
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
|
KR20120105405A
(ko)
|
2009-06-23 |
2012-09-25 |
알렉시온 파마슈티칼스, 인코포레이티드 |
보체 단백질에 결합하는 이중특이적 항체
|
|
KR20120051002A
(ko)
|
2009-07-07 |
2012-05-21 |
제넨테크, 인크. |
자가면역 탈수초성 질환의 진단 및 치료
|
|
CA2768013C
(en)
|
2009-07-15 |
2018-08-21 |
Prometheus Laboratories Inc. |
Drug selection for gastric cancer therapy using antibody-based arrays
|
|
EP2757160A3
(en)
|
2009-07-20 |
2014-07-30 |
Genentech, Inc. |
Gene expression markers for Crohn's disease
|
|
AR077595A1
(es)
|
2009-07-27 |
2011-09-07 |
Genentech Inc |
Tratamientos de combinacion
|
|
SG178177A1
(en)
|
2009-07-31 |
2012-03-29 |
Genentech Inc |
Inhibition of tumor metastasis using bv8- or g-csf-antagonists
|
|
US20130017188A1
(en)
|
2009-07-31 |
2013-01-17 |
The Brigham And Women's Hospital, Inc. |
Modulation of sgk1 expression in th17 cells to modulate th17-mediated immune responses
|
|
WO2011019620A1
(en)
|
2009-08-10 |
2011-02-17 |
Genentech, Inc. |
Antibodies with enhanced adcc function
|
|
SI2464725T2
(sl)
|
2009-08-11 |
2025-06-30 |
F. Hoffmann-La Roche Ag |
Proizvodnja beljakovin v medijih za celične kulture brez glutamina
|
|
US20110038871A1
(en)
|
2009-08-11 |
2011-02-17 |
Veena Viswanth |
Ccr2 inhibitors for treating conditions of the eye
|
|
WO2011019622A1
(en)
|
2009-08-14 |
2011-02-17 |
Genentech, Inc. |
Cell culture methods to make antibodies with enhanced adcc function
|
|
JP6088246B2
(ja)
|
2009-08-15 |
2017-03-01 |
ジェネンテック, インコーポレイテッド |
以前に治療された乳癌の治療のための抗血管新生療法
|
|
CN102686738A
(zh)
|
2009-09-01 |
2012-09-19 |
弗·哈夫曼-拉罗切有限公司 |
通过改进的a蛋白洗脱增强的蛋白质纯化
|
|
JP2013503846A
(ja)
|
2009-09-01 |
2013-02-04 |
ファイザー・インク |
ベンズイミダゾール誘導体
|
|
US9321823B2
(en)
|
2009-09-02 |
2016-04-26 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
|
MX2012003396A
(es)
|
2009-09-16 |
2012-04-10 |
Genentech Inc |
Complejos de proteina conteniendo helice super-enrollada y/o enlazador tether y usos de los mismos.
|
|
NZ599460A
(en)
|
2009-10-20 |
2014-07-25 |
Nestec Sa |
Proximity-mediated assays for detecting oncogenic fusion proteins
|
|
JP2013508401A
(ja)
|
2009-10-22 |
2013-03-07 |
ジェネンテック, インコーポレイテッド |
軸索変性の調節
|
|
AU2010310585A1
(en)
|
2009-10-22 |
2012-05-03 |
Genentech, Inc. |
Anti-hepsin antibodies and methods using same
|
|
BR112012009409A2
(pt)
|
2009-10-22 |
2017-02-21 |
Genentech Inc |
método de identificação de uma substância inibidora, molécula antagonista, ácido nucleico isolado, vetor, célula hospedeira, método para fabricar a molécula, composição, artigo de fabricação, método de inibição de uma atividade biológica, método de tratamento de uma condição patológica, método para detectar msp em uma amostra e método para detectar hepsina em uma amostra
|
|
WO2011056494A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor-like kinase-1 antagonist and vegfr3 antagonist combinations
|
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
|
WO2011056997A1
(en)
|
2009-11-04 |
2011-05-12 |
Fabrus Llc |
Methods for affinity maturation-based antibody optimization
|
|
CA2780143A1
(en)
|
2009-11-05 |
2011-05-12 |
Genentech, Inc. |
Methods and composition for secretion of heterologous polypeptides
|
|
TWI507524B
(zh)
|
2009-11-30 |
2015-11-11 |
Genentech Inc |
診斷及治療腫瘤之組合物及方法
|
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
|
EP2506876B1
(en)
|
2009-12-02 |
2016-10-12 |
Imaginab, Inc. |
J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use
|
|
US11377485B2
(en)
|
2009-12-02 |
2022-07-05 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
|
WO2011071577A1
(en)
|
2009-12-11 |
2011-06-16 |
Genentech, Inc. |
Anti-vegf-c antibodies and methods using same
|
|
CN107095846A
(zh)
|
2009-12-21 |
2017-08-29 |
霍夫曼-拉罗奇有限公司 |
抗体配制剂
|
|
RU2559542C2
(ru)
|
2009-12-23 |
2015-08-10 |
Дженентек, Инк. |
Антитела против bv8 и их применение
|
|
ES2701626T3
(es)
|
2009-12-28 |
2019-02-25 |
Oncotherapy Science Inc |
Anticuerpos anti-CDH3 y sus usos
|
|
WO2011082187A1
(en)
|
2009-12-30 |
2011-07-07 |
Genentech, Inc. |
Methods for modulating a pdgf-aa mediated biological response
|
|
EP2533810B1
(en)
|
2010-02-10 |
2016-10-12 |
ImmunoGen, Inc. |
Cd20 antibodies and uses thereof
|
|
RS55487B2
(sr)
|
2010-02-12 |
2024-06-28 |
Pfizer |
Soli i polimorfi 8-fluoro-2-{4-[(metilamino}metil]fenil}-1,3,4,5-tetrahidro-6h-azepino[5,4,3-cd]indol-6-ona
|
|
SG183333A1
(en)
|
2010-02-18 |
2012-09-27 |
Genentech Inc |
Neuregulin antagonists and use thereof in treating cancer
|
|
JP6025256B2
(ja)
*
|
2010-02-23 |
2016-11-16 |
コーニング インコーポレイテッド |
ペプチド固定化表面をγ線劣化から保護するための修飾基板
|
|
MA34057B1
(fr)
|
2010-02-23 |
2013-03-05 |
Genentech Inc |
Compositions et methodes pour le diagnostic et le traitement d'une tumeur
|
|
CN103237810A
(zh)
|
2010-02-23 |
2013-08-07 |
霍夫曼-拉罗奇有限公司 |
用于治疗卵巢癌的抗血管发生疗法
|
|
AU2011223655A1
(en)
|
2010-03-03 |
2012-06-28 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
|
EP2519826A2
(en)
|
2010-03-03 |
2012-11-07 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
|
WO2011116396A2
(en)
|
2010-03-19 |
2011-09-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
Hepatocyte growth factor fragments that function as potent met receptor agonists and antagonists
|
|
JP6093692B2
(ja)
|
2010-03-24 |
2017-03-08 |
ジェネンテック, インコーポレイテッド |
抗lrp6抗体
|
|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
|
WO2011130332A1
(en)
|
2010-04-12 |
2011-10-20 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
|
WO2011133931A1
(en)
|
2010-04-22 |
2011-10-27 |
Genentech, Inc. |
Use of il-27 antagonists for treating inflammatory bowel disease
|
|
JP2013533732A
(ja)
|
2010-05-03 |
2013-08-29 |
ジェネンテック, インコーポレイテッド |
腫瘍の診断と治療のための組成物と方法
|
|
DK2568976T3
(en)
|
2010-05-10 |
2016-01-11 |
Academia Sinica |
Zanamivir-phosphonate congener with the anti-influenza activity, and determining the sensitivity oseltamivir in influenza viruses
|
|
CN107312062B
(zh)
|
2010-05-17 |
2021-03-16 |
Emd密理博公司 |
用于纯化生物分子的刺激响应性聚合物
|
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
|
EP4492053A3
(en)
|
2010-05-25 |
2025-03-19 |
F. Hoffmann-La Roche AG |
Methods of purifying polypeptides
|
|
WO2011147834A1
(en)
|
2010-05-26 |
2011-12-01 |
Roche Glycart Ag |
Antibodies against cd19 and uses thereof
|
|
KR20190067277A
(ko)
|
2010-05-28 |
2019-06-14 |
제넨테크, 인크. |
락테이트 데히드로게나제 및 피루베이트 데히드로게나제 키나제의 발현의 하향조절에 의한 락테이트 수준의 감소 및 폴리펩티드 생산의 증가
|
|
WO2011153243A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Anti-angiogenesis therapy for treating gastric cancer
|
|
AU2011261362B2
(en)
|
2010-06-03 |
2016-06-09 |
Genentech, Inc. |
Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
|
|
CA2799540A1
(en)
|
2010-06-08 |
2011-12-15 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
EP2582727B8
(en)
|
2010-06-16 |
2017-04-19 |
University of Pittsburgh- Of the Commonwealth System of Higher Education |
Antibodies to endoplasmin and their use
|
|
US20110311527A1
(en)
|
2010-06-16 |
2011-12-22 |
Allergan, Inc. |
IL23p19 ANTIBODY INHIBITOR FOR TREATING OCULAR AND OTHER CONDITIONS
|
|
JP5940061B2
(ja)
|
2010-06-18 |
2016-06-29 |
ジェネンテック, インコーポレイテッド |
抗axl抗体及び使用方法
|
|
WO2011161119A1
(en)
|
2010-06-22 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Antibodies against insulin-like growth factor i receptor and uses thereof
|
|
WO2011161189A1
(en)
|
2010-06-24 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Anti-hepsin antibodies and methods of use
|
|
RU2571226C2
(ru)
|
2010-07-09 |
2015-12-20 |
Дженентек, Инк. |
Антитела против нейропилина и способы их применения
|
|
JP2013532628A
(ja)
|
2010-07-16 |
2013-08-19 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
乳癌および/または骨転移の処置に用いるためのペプチド
|
|
WO2012010582A1
(en)
|
2010-07-21 |
2012-01-26 |
Roche Glycart Ag |
Anti-cxcr5 antibodies and methods of use
|
|
AU2011280969A1
(en)
|
2010-07-23 |
2013-02-07 |
Trustees Of Boston University |
Anti-Despr inhibitors as therapeutics for inhibition of pathological angiogenesis and tumor cell invasiveness and for molecular imaging and targeted delivery
|
|
RU2013106216A
(ru)
|
2010-08-03 |
2014-09-10 |
Ф. Хоффманн-Ля Рош Аг |
Биомаркеры хронической лимфоцитарной лейкемии
|
|
WO2012017003A1
(en)
|
2010-08-05 |
2012-02-09 |
F. Hoffmann-La Roche Ag |
Anti-mhc antibody anti-viral cytokine fusion protein
|
|
EP2420250A1
(en)
|
2010-08-13 |
2012-02-22 |
Universitätsklinikum Münster |
Anti-Syndecan-4 antibodies
|
|
EP2603237A4
(en)
|
2010-08-12 |
2014-05-21 |
Theraclone Sciences Inc |
ANTI-HEMAGGLUTININE ANTIBODY COMPOSITIONS AND METHOD FOR THEIR USE
|
|
HUE036077T2
(hu)
|
2010-08-13 |
2018-06-28 |
Roche Glycart Ag |
Anti-FAP ellenanyagok és alkalmazásukra szolgáló eljárások
|
|
CA2806640A1
(en)
|
2010-08-13 |
2012-02-16 |
Roche Glycart Ag |
Anti-tenascin-c a2 antibodies and methods of use
|
|
CN103068846B9
(zh)
|
2010-08-24 |
2016-09-28 |
弗·哈夫曼-拉罗切有限公司 |
包含二硫键稳定性Fv片段的双特异性抗体
|
|
RU2013110874A
(ru)
|
2010-08-25 |
2014-09-27 |
Ф.Хоффманн-Ля Рош Аг |
Антитела против il-18r1 и их применения
|
|
EP4549461A3
(en)
|
2010-08-31 |
2025-08-06 |
Theraclone Sciences, Inc. |
Human immunodeficiency virus (hiv)-neutralizing antibodies
|
|
JP2013537966A
(ja)
|
2010-08-31 |
2013-10-07 |
ジェネンテック, インコーポレイテッド |
バイオマーカー及び治療の方法
|
|
WO2012028683A1
(en)
|
2010-09-02 |
2012-03-08 |
Novartis Ag |
Antibody gel system for sustained drug delivery
|
|
WO2012030512A1
(en)
|
2010-09-03 |
2012-03-08 |
Percivia Llc. |
Flow-through protein purification process
|
|
MX349622B
(es)
|
2010-09-08 |
2017-08-07 |
Halozyme Inc |
Metodos para evaluar e identificar o evolucionar proteinas terapeuticas condicionalmente activas.
|
|
US8481680B2
(en)
|
2010-10-05 |
2013-07-09 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
|
EP2630134B9
(en)
|
2010-10-20 |
2018-04-18 |
Pfizer Inc |
Pyridine-2- derivatives as smoothened receptor modulators
|
|
WO2012061129A1
(en)
|
2010-10-25 |
2012-05-10 |
Genentech, Inc |
Treatment of gastrointestinal inflammation and psoriasis a
|
|
WO2012064836A1
(en)
|
2010-11-10 |
2012-05-18 |
Genentech, Inc. |
Methods and compositions for neural disease immunotherapy
|
|
WO2012071436A1
(en)
|
2010-11-24 |
2012-05-31 |
Genentech, Inc. |
Method of treating autoimmune inflammatory disorders using il-23r loss-of-function mutants
|
|
WO2012069466A1
(en)
|
2010-11-24 |
2012-05-31 |
Novartis Ag |
Multispecific molecules
|
|
WO2012075333A2
(en)
|
2010-12-02 |
2012-06-07 |
Prometheus Laboratories Inc. |
Her2delta16 peptides
|
|
EP3447491A3
(en)
|
2010-12-16 |
2019-06-05 |
F. Hoffmann-La Roche AG |
Diagnosis and treatments relating to th2 inhibition
|
|
TWI477513B
(zh)
|
2010-12-20 |
2015-03-21 |
建南德克公司 |
抗間皮素(mesothelin)抗體及免疫接合物
|
|
CA2820953A1
(en)
|
2010-12-22 |
2012-06-28 |
Genentech, Inc. |
Anti-pcsk9 antibodies and methods of use
|
|
JP6046049B2
(ja)
|
2010-12-23 |
2016-12-14 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
二価結合剤による翻訳後修飾されたポリペプチドの検出
|
|
SG191153A1
(en)
|
2010-12-23 |
2013-07-31 |
Hoffmann La Roche |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
|
CN103384681B
(zh)
|
2010-12-23 |
2018-05-18 |
霍夫曼-拉罗奇有限公司 |
结合剂
|
|
EP2659275B1
(en)
|
2010-12-23 |
2017-11-22 |
Roche Diagnostics GmbH |
Detection of a polypeptide dimer by a bivalent binding agent
|
|
MX2013007429A
(es)
|
2010-12-23 |
2014-01-31 |
Nestec Sa |
Seleccion de farmacos para terapia de cancer maligno usando disposiciones a base de anticuerpos.
|
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
|
CN105440123B
(zh)
|
2011-02-10 |
2020-10-09 |
罗切格利卡特公司 |
突变体白介素-2多肽
|
|
JP2014511147A
(ja)
|
2011-02-10 |
2014-05-12 |
ロシュ グリクアート アーゲー |
改善された免疫療法
|
|
CA2827301A1
(en)
|
2011-02-14 |
2012-08-23 |
Theraclone Sciences, Inc. |
Compositions and methods for the therapy and diagnosis of influenza
|
|
US20120214830A1
(en)
|
2011-02-22 |
2012-08-23 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma
|
|
BR112013020338A2
(pt)
|
2011-02-28 |
2016-10-18 |
Hoffmann La Roche |
proteína de ligação de antígeno monovalente, composição farmacêutica, uso da proteína de ligação de antígeno monovalente, método para o tratamento de um paciente com necessidade de terapia, método para a preparação de uma proteína de ligação de antígeno monovalente, ácido nucleico, vetor e célula hospedeira
|
|
WO2012116926A1
(en)
|
2011-02-28 |
2012-09-07 |
F. Hoffmann-La Roche Ag |
Antigen binding proteins
|
|
JP6101638B2
(ja)
|
2011-03-03 |
2017-03-22 |
ザイムワークス,インコーポレイテッド |
多価ヘテロマルチマー足場設計及び構築物
|
|
WO2012119989A2
(en)
|
2011-03-04 |
2012-09-13 |
Oryzon Genomics, S.A. |
Methods and antibodies for the diagnosis and treatment of cancer
|
|
WO2012122499A2
(en)
|
2011-03-09 |
2012-09-13 |
Pestell Richard G |
Prostate cancer cell lines, gene signatures and uses thereof
|
|
SG193402A1
(en)
|
2011-03-15 |
2013-10-30 |
Theraclone Sciences Inc |
Compositions and methods for the therapy and diagnosis of influenza
|
|
AR085911A1
(es)
|
2011-03-16 |
2013-11-06 |
Sanofi Sa |
Dosis terapeutica segura de una proteina similar a un anticuerpo con region v dual
|
|
SI2691417T2
(sl)
|
2011-03-29 |
2025-05-30 |
Roche Glycart Ag |
FC variante protitelesa
|
|
AU2012236304C1
(en)
|
2011-03-31 |
2017-01-05 |
Genentech, Inc. |
Methods of administering beta7 integrin antagonists
|
|
CN103596983B
(zh)
|
2011-04-07 |
2016-10-26 |
霍夫曼-拉罗奇有限公司 |
抗fgfr4抗体及使用方法
|
|
US9150644B2
(en)
|
2011-04-12 |
2015-10-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
|
|
WO2012145183A2
(en)
|
2011-04-19 |
2012-10-26 |
Pfizer Inc. |
Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
|
|
BR112013026423A2
(pt)
|
2011-04-20 |
2016-11-29 |
Roche Glycart Ag |
método e construtos para a passagem de pendente do ph da barreira sangue-cérebro
|
|
JP2014519813A
(ja)
|
2011-04-25 |
2014-08-21 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
癌薬剤発見、診断、および治療におけるemt遺伝子シグネチャーの使用
|
|
EA201892619A1
(ru)
|
2011-04-29 |
2019-04-30 |
Роше Гликарт Аг |
Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
|
|
MX2013013054A
(es)
|
2011-05-12 |
2014-02-20 |
Genentech Inc |
Metodo de monitoreo de lc-ms/ms de reaccion multiple para detectar anticuerpos terapeuticos en muestras de animales utilizando peptidos de firma de estructura.
|
|
ES2628385T3
(es)
|
2011-05-16 |
2017-08-02 |
F. Hoffmann-La Roche Ag |
Agonistas de FGFR1 y procedimientos de uso
|
|
RU2013158627A
(ru)
|
2011-06-15 |
2015-07-20 |
Ф. Хоффманн-Ля Рош Аг |
Антитела к рецептору человеческого эритропоэтина и способы их применения
|
|
AR086823A1
(es)
|
2011-06-30 |
2014-01-22 |
Genentech Inc |
Formulaciones de anticuerpo anti-c-met, metodos
|
|
JP2013040160A
(ja)
|
2011-07-01 |
2013-02-28 |
Genentech Inc |
自己免疫疾患を治療するための抗cd83アゴニスト抗体の使用
|
|
HRP20180858T1
(hr)
|
2011-07-11 |
2018-09-21 |
Glenmark Pharmaceuticals S.A. |
Protutijela koja se vežu na ox40 i njihove uporabe
|
|
ES2671748T3
(es)
|
2011-07-21 |
2018-06-08 |
Tolero Pharmaceuticals, Inc. |
Inhibidores heterocíclicos de proteína quinasas
|
|
US9120858B2
(en)
|
2011-07-22 |
2015-09-01 |
The Research Foundation Of State University Of New York |
Antibodies to the B12-transcobalamin receptor
|
|
US20130022551A1
(en)
|
2011-07-22 |
2013-01-24 |
Trustees Of Boston University |
DEspR ANTAGONISTS AND AGONISTS AS THERAPEUTICS
|
|
WO2013015821A1
(en)
|
2011-07-22 |
2013-01-31 |
The Research Foundation Of State University Of New York |
Antibodies to the b12-transcobalamin receptor
|
|
CA2842375A1
(en)
|
2011-08-17 |
2013-02-21 |
Erica Jackson |
Neuregulin antibodies and uses thereof
|
|
CN103890008A
(zh)
|
2011-08-17 |
2014-06-25 |
霍夫曼-拉罗奇有限公司 |
在顽固性肿瘤中抑制血管发生
|
|
KR20140048292A
(ko)
|
2011-08-23 |
2014-04-23 |
로슈 글리카트 아게 |
항-mcsp 항체
|
|
NO2748201T3
(OSRAM)
|
2011-08-23 |
2018-05-12 |
|
|
|
RU2650775C2
(ru)
|
2011-08-23 |
2018-04-17 |
Рош Гликарт Аг |
Биспецифические антигенсвязывающие молекулы
|
|
KR101681818B1
(ko)
|
2011-08-23 |
2016-12-01 |
로슈 글리카트 아게 |
T 세포 활성화 항원 및 종양 항원에 대해 특이적인 이중특이적 항체 및 이의 사용 방법
|
|
US20130078250A1
(en)
|
2011-08-23 |
2013-03-28 |
Oliver Ast |
Bispecific t cell activating antigen binding molecules
|
|
WO2013033069A1
(en)
|
2011-08-30 |
2013-03-07 |
Theraclone Sciences, Inc. |
Human rhinovirus (hrv) antibodies
|
|
WO2013033623A1
(en)
|
2011-09-02 |
2013-03-07 |
Nestec S.A. |
Profiling of signal pathway proteins to determine therapeutic efficacy
|
|
GB201212550D0
(en)
|
2012-07-13 |
2012-08-29 |
Novartis Ag |
B cell assay
|
|
CN103930781A
(zh)
|
2011-09-15 |
2014-07-16 |
霍夫曼-拉罗奇有限公司 |
促进分化的方法
|
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
|
KR20140064971A
(ko)
|
2011-09-19 |
2014-05-28 |
제넨테크, 인크. |
c-met 길항제 및 B-raf 길항제를 포함하는 조합 치료
|
|
PH12014500638A1
(en)
|
2011-09-22 |
2017-08-09 |
Pfizer |
Pyrrolopyrimidine and purine derivatives
|
|
EP2764025B1
(en)
|
2011-10-04 |
2017-11-29 |
IGEM Therapeutics Limited |
Ige-antibodies against hmw-maa
|
|
US20130089562A1
(en)
|
2011-10-05 |
2013-04-11 |
Genenthech, Inc. |
Methods of treating liver conditions using notch2 antagonists
|
|
CA2850032C
(en)
|
2011-10-14 |
2022-06-07 |
Genentech, Inc. |
Anti-htra1 antibodies and methods of use
|
|
BR112014008590A2
(pt)
|
2011-10-15 |
2017-10-24 |
Genentech Inc |
métodos de uso de antagonistas de scd1
|
|
WO2013059531A1
(en)
|
2011-10-20 |
2013-04-25 |
Genentech, Inc. |
Anti-gcgr antibodies and uses thereof
|
|
US9327023B2
(en)
|
2011-10-25 |
2016-05-03 |
The Regents Of The University Of Michigan |
HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells
|
|
JP6251682B2
(ja)
|
2011-10-28 |
2017-12-20 |
ジェネンテック, インコーポレイテッド |
メラノーマ治療の治療の組み合わせ及び方法
|
|
RS58472B2
(sr)
|
2011-11-02 |
2024-10-31 |
Hoffmann La Roche |
Hromatografija preopterećenja i eluata
|
|
AU2012335247A1
(en)
|
2011-11-08 |
2014-05-29 |
Pfizer Inc. |
Methods of treating inflammatory disorders using anti-M-CSF antibodies
|
|
CN104066748A
(zh)
|
2011-11-21 |
2014-09-24 |
霍夫曼-拉罗奇有限公司 |
抗c-met抗体的纯化
|
|
WO2013078377A1
(en)
|
2011-11-23 |
2013-05-30 |
Igenica, Inc. |
Anti-cd98 antibodies and methods of use thereof
|
|
AR089028A1
(es)
|
2011-11-29 |
2014-07-23 |
Genentech Inc |
Composiciones y metodos para el analisis de cancer de prostata
|
|
EP2785864A2
(en)
|
2011-11-30 |
2014-10-08 |
F. Hoffmann-La Roche AG |
Erbb3 mutations in cancer
|
|
WO2013083497A1
(en)
|
2011-12-06 |
2013-06-13 |
F. Hoffmann-La Roche Ag |
Antibody formulation
|
|
WO2013083810A1
(en)
|
2011-12-09 |
2013-06-13 |
F. Hoffmann-La Roche Ag |
Identification of non-responders to her2 inhibitors
|
|
WO2013091903A1
(en)
|
2011-12-22 |
2013-06-27 |
Novo Nordisk A/S |
Anti-crac channel antibodies
|
|
US20160208284A1
(en)
|
2011-12-22 |
2016-07-21 |
Hoffmann-La Roche Inc. |
Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides
|
|
HRP20181846T1
(hr)
|
2011-12-22 |
2018-12-28 |
Genentech, Inc. |
Kromatografija membranom za ionsku izmjenu
|
|
RU2756106C2
(ru)
|
2011-12-22 |
2021-09-28 |
Ф. Хоффманн-Ля Рош Аг |
Строение экспрессионного вектора, новые способы получения клеток-продуцентов и их применение для рекомбинантного получения полипептидов
|
|
WO2013096791A1
(en)
|
2011-12-23 |
2013-06-27 |
Genentech, Inc. |
Process for making high concentration protein formulations
|
|
WO2013101771A2
(en)
|
2011-12-30 |
2013-07-04 |
Genentech, Inc. |
Compositions and method for treating autoimmune diseases
|
|
JP6684490B2
(ja)
|
2012-01-09 |
2020-04-22 |
ザ・スクリップス・リサーチ・インスティテュート |
超長相補性決定領域及びその使用
|
|
CA2862979A1
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Humanized antibodies with ultralong cdr3s
|
|
MX2014008699A
(es)
|
2012-01-18 |
2014-11-21 |
Genentech Inc |
Metodos para utilizar moduladores de fgf19.
|
|
PE20141561A1
(es)
|
2012-01-18 |
2014-11-12 |
Genentech Inc |
Anticuerpos anti-lrp5 y metodos de uso
|
|
WO2013113641A1
(en)
|
2012-01-31 |
2013-08-08 |
Roche Glycart Ag |
Use of nkp46 as a predictive biomarker for cancer treatment with adcc- enhanced antibodies
|
|
TW201334789A
(zh)
|
2012-01-31 |
2013-09-01 |
Genentech Inc |
抗ige抗體及其使用方法
|
|
CN104105711B
(zh)
|
2012-02-10 |
2018-11-30 |
弗·哈夫曼-拉罗切有限公司 |
单链抗体及其他异多聚体
|
|
WO2013120056A1
(en)
|
2012-02-11 |
2013-08-15 |
Genentech, Inc. |
R-spondin translocations and methods using the same
|
|
WO2013120929A1
(en)
|
2012-02-15 |
2013-08-22 |
F. Hoffmann-La Roche Ag |
Fc-receptor based affinity chromatography
|
|
MX2014010379A
(es)
|
2012-03-02 |
2015-05-15 |
Roche Glycart Ag |
Biomarcador predictivo para tratamiento de cancer con anticuerpos mejorados en adcc.
|
|
NZ630020A
(en)
|
2012-03-08 |
2016-08-26 |
Halozyme Inc |
Conditionally active anti-epidermal growth factor receptor antibodies and methods of use thereof
|
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
|
CA2865082A1
(en)
|
2012-03-27 |
2013-10-03 |
Genentech, Inc. |
Diagnosis and treatments relating to her3 inhibitors
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
|
RU2014148162A
(ru)
|
2012-05-01 |
2016-06-20 |
Дженентек, Инк. |
Анти-pmel17 антитела и их иммуноконъюгаты
|
|
AU2013258834B2
(en)
|
2012-05-10 |
2017-09-07 |
Zymeworks Bc Inc. |
Heteromultimer constructs of immunoglobulin heavy chains with mutations in the Fc domain
|
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
|
EP2861302A4
(en)
|
2012-05-14 |
2016-08-24 |
Prostagene Llc |
USE OF CCR5 MODULATORS IN THE TREATMENT OF CANCER
|
|
KR101843614B1
(ko)
|
2012-05-23 |
2018-03-29 |
제넨테크, 인크. |
치료제의 선택 방법
|
|
UA113879C2
(xx)
|
2012-06-08 |
2017-03-27 |
|
ГУМАНІЗОВАНЕ АНТИТІЛО ПРОТИ ТrkА З АМІНОКИСЛОТНИМИ ЗАМІЩЕННЯМИ
|
|
US9266961B2
(en)
|
2012-06-15 |
2016-02-23 |
Genentech, Inc. |
Anti-PCSK9 antibodies, formulations, dosing, and methods of use
|
|
EP2867254B1
(en)
|
2012-06-27 |
2017-10-25 |
F. Hoffmann-La Roche AG |
Method for making antibody fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof
|
|
WO2014001326A1
(en)
|
2012-06-27 |
2014-01-03 |
F. Hoffmann-La Roche Ag |
Method for the selection and production of tailor-made, selective and multi-specific therapeutic molecules comprising at least two different targeting entities and uses thereof
|
|
KR20150023889A
(ko)
|
2012-06-27 |
2015-03-05 |
에프. 호프만-라 로슈 아게 |
2 개 이상의 상이한 결합 단위를 함유하는 맞춤-제작된 고도로 선별적이고 다중-특이적인 표적화 단위의 선별 및 제조 방법 및 이의 용도
|
|
ES2600154T3
(es)
|
2012-07-04 |
2017-02-07 |
F. Hoffmann-La Roche Ag |
Anticuerpos antiteofilina y métodos de uso
|
|
BR112014030844A2
(pt)
|
2012-07-04 |
2019-10-15 |
Hoffmann La Roche |
anticorpo anti-biotina humanizado, formulação farmacêutica e uso do anticorpo
|
|
CA2871112C
(en)
|
2012-07-04 |
2020-05-12 |
F. Hoffmann-La Roche Ag |
Covalently linked antigen-antibody conjugates
|
|
EP3578660A1
(en)
|
2012-07-05 |
2019-12-11 |
F. Hoffmann-La Roche AG |
Expression and secretion system
|
|
EP2869847B1
(en)
|
2012-07-09 |
2017-12-06 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd79b antibodies
|
|
HK1209043A1
(en)
|
2012-07-09 |
2016-03-24 |
基因泰克公司 |
Immunoconjugates comprising anti-cd22 antibodies
|
|
US20140030280A1
(en)
|
2012-07-09 |
2014-01-30 |
Genentech, Inc. |
Anti-cd79b antibodies and immunoconjugates
|
|
BR112015000439A2
(pt)
|
2012-07-09 |
2017-12-19 |
Genentech Inc |
imunoconjugado , formulação farmacêutica e métodos de tratamento de um indivíduo e de inibição da proliferação
|
|
PE20150361A1
(es)
|
2012-07-13 |
2015-03-14 |
Roche Glycart Ag |
Anticuerpos biespecificos anti-vegf/anti-ang-2 y su utilizacion en el tratamiento de enfermedades vasculares oculares
|
|
WO2014012082A2
(en)
|
2012-07-13 |
2014-01-16 |
Zymeworks Inc. |
Multivalent heteromultimer scaffold design an constructs
|
|
CN103566377A
(zh)
|
2012-07-18 |
2014-02-12 |
上海博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
|
CA2872195A1
(en)
|
2012-08-07 |
2014-02-13 |
Roche Glycart Ag |
Composition comprising two antibodies engineered to have reduced and increased effector function
|
|
SG11201408526SA
(en)
|
2012-08-08 |
2015-03-30 |
Roche Glycart Ag |
Interleukin-10 fusion proteins and uses thereof
|
|
CN104704001B
(zh)
|
2012-08-09 |
2019-02-12 |
罗切格利卡特公司 |
Asgpr抗体及其用途
|
|
EP2885311B1
(en)
|
2012-08-18 |
2020-01-01 |
Academia Sinica |
Cell-permeable probes for identification and imaging of sialidases
|
|
US9547009B2
(en)
|
2012-08-21 |
2017-01-17 |
Academia Sinica |
Benzocyclooctyne compounds and uses thereof
|
|
WO2014036520A1
(en)
|
2012-08-30 |
2014-03-06 |
Merrimack Pharmaceuticals, Inc. |
Combination therapies comprising anti-erbb3 agents
|
|
KR20150052085A
(ko)
|
2012-09-14 |
2015-05-13 |
에프. 호프만-라 로슈 아게 |
2개 이상의 상이한 단위를 포함하는 분자의 제조 및 선별 방법, 및 이의 용도
|
|
MX372664B
(es)
|
2012-10-05 |
2020-05-06 |
Genentech Inc |
Un antagonista de integrina beta7 para usarse en diagnosticar y tratar la enfermedad inflamatoria intestinal.
|
|
EP2904016B1
(en)
|
2012-10-08 |
2018-11-14 |
Roche Glycart AG |
Fc-free antibodies comprising two fab-fragments and methods of use
|
|
SG11201502757QA
(en)
|
2012-10-09 |
2015-05-28 |
Igenica Biotherapeutics Inc |
Anti-c16orf54 antibodies and methods of use thereof
|
|
EP2909181B1
(en)
|
2012-10-16 |
2017-08-09 |
Tolero Pharmaceuticals, Inc. |
Pkm2 modulators and methods for their use
|
|
AU2013337264B2
(en)
|
2012-11-05 |
2018-03-08 |
Foundation Medicine, Inc. |
Novel fusion molecules and uses thereof
|
|
EP2914621B1
(en)
|
2012-11-05 |
2023-06-07 |
Foundation Medicine, Inc. |
Novel ntrk1 fusion molecules and uses thereof
|
|
AR093378A1
(es)
|
2012-11-08 |
2015-06-03 |
Hoffmann La Roche |
PROTEINAS LIGANTES DE ANTIGENO HER3 DE UNION A LA HORQUILLA b DE HER3
|
|
BR112015010817A8
(pt)
|
2012-11-13 |
2018-01-23 |
Genentech Inc |
anticorpos anti-hemaglutinina isolado, método de tratamento, inibição ou prevenção de infecções, composição, composição farmacêutica, ácido nucleico isolado, célula hospedeira, método de produção de anticorpos e uso do anticorpo anti-hemaglutinina
|
|
CA2890979A1
(en)
|
2012-11-15 |
2014-05-22 |
Genentech, Inc. |
Ionic strength-mediated ph gradient ion exchange chromatography
|
|
CA2889298C
(en)
|
2012-11-30 |
2024-01-02 |
Anton Belousov |
Identification of patients in need of pd-l1 inhibitor cotherapy
|
|
US9260426B2
(en)
|
2012-12-14 |
2016-02-16 |
Arrien Pharmaceuticals Llc |
Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
|
|
SG11201505186SA
(en)
|
2013-01-02 |
2015-07-30 |
Glenmark Pharmaceuticals Sa |
Antibodies that bind to tl1a and their uses
|
|
AU2014207342C1
(en)
|
2013-01-18 |
2019-04-04 |
Foundation Medicine, Inc. |
Methods of treating cholangiocarcinoma
|
|
WO2014114595A1
(en)
|
2013-01-23 |
2014-07-31 |
Roche Glycart Ag |
Predictive biomarker for cancer treatment with adcc-enhanced antibodies
|
|
WO2014116749A1
(en)
|
2013-01-23 |
2014-07-31 |
Genentech, Inc. |
Anti-hcv antibodies and methods of using thereof
|
|
WO2014128235A1
(en)
|
2013-02-22 |
2014-08-28 |
F. Hoffmann-La Roche Ag |
Methods of treating cancer and preventing drug resistance
|
|
KR20180023035A
(ko)
|
2013-02-26 |
2018-03-06 |
로슈 글리카트 아게 |
이중특이적 t 세포 활성화 항원 결합 분자
|
|
EP3444278A1
(en)
|
2013-02-26 |
2019-02-20 |
Roche Glycart AG |
Bispecific t cell activating antigen binding molecules
|
|
MX2015010843A
(es)
|
2013-02-26 |
2016-04-04 |
Roche Glycart Ag |
Moleculas biespecificas de union al antigeno que activan celulas t.
|
|
CN104936987A
(zh)
|
2013-02-26 |
2015-09-23 |
罗切格利卡特公司 |
抗mcsp抗体
|
|
HK1213180A1
(zh)
|
2013-03-06 |
2016-06-30 |
豪夫迈‧罗氏有限公司 |
治疗和预防癌症药物抗性的方法
|
|
NZ711567A
(en)
|
2013-03-13 |
2020-04-24 |
Genentech Inc |
Antibody formulations
|
|
MY174679A
(en)
|
2013-03-13 |
2020-05-06 |
Genentech Inc |
Formulations with reduced oxidation
|
|
RS60534B1
(sr)
|
2013-03-13 |
2020-08-31 |
Hoffmann La Roche |
Formulacije sa smanjenom oksidacijom
|
|
US10653779B2
(en)
|
2013-03-13 |
2020-05-19 |
Genentech, Inc. |
Formulations with reduced oxidation
|
|
US20140314778A1
(en)
|
2013-03-13 |
2014-10-23 |
Genentech, Inc. |
Formulations with reduced oxidation
|
|
JP2016515132A
(ja)
|
2013-03-14 |
2016-05-26 |
ジェネンテック, インコーポレイテッド |
Mek阻害剤化合物のher3/egfr阻害剤化合物との組み合わせ及び使用方法
|
|
HK1220916A1
(zh)
|
2013-03-14 |
2017-05-19 |
基因泰克公司 |
治疗癌症和预防癌症药物抗性的方法
|
|
AU2014244424A1
(en)
|
2013-03-14 |
2015-08-27 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
JP6433974B2
(ja)
|
2013-03-14 |
2018-12-05 |
トレロ ファーマシューティカルズ, インコーポレイテッド |
Jak2およびalk2阻害剤およびその使用方法
|
|
KR20150131269A
(ko)
|
2013-03-15 |
2015-11-24 |
제넨테크, 인크. |
Pd-1 및 pd-l1 관련 상태를 치료하기 위한 바이오마커 및 방법
|
|
MX2015012326A
(es)
|
2013-03-15 |
2016-03-08 |
Genentech Inc |
Anticuerpos anti-crth2 y su uso.
|
|
KR20210037745A
(ko)
|
2013-03-15 |
2021-04-06 |
제넨테크, 인크. |
항산화제를 함유하는 세포 배양 조성물 및 폴리펩티드 생산 방법
|
|
AR095348A1
(es)
|
2013-03-15 |
2015-10-07 |
Genentech Inc |
Medios de cultivo celular y métodos de producción de anticuerpos
|
|
MX2015011444A
(es)
|
2013-03-15 |
2015-12-16 |
Genentech Inc |
Composiciones y metodos para el diagnostico y tratamiento del cancer hepatico.
|
|
US20140283157A1
(en)
|
2013-03-15 |
2014-09-18 |
Diadexus, Inc. |
Lipoprotein-associated phospholipase a2 antibody compositions and methods of use
|
|
EP2970452A2
(en)
|
2013-03-15 |
2016-01-20 |
AC Immune S.A. |
Anti-tau antibodies and methods of use
|
|
RU2015143437A
(ru)
|
2013-03-15 |
2017-04-27 |
Дженентек, Инк. |
Способы лечения рака и предотвращения устойчивости к лекарственным препаратам для лечения рака
|
|
EA201591495A1
(ru)
|
2013-03-18 |
2016-05-31 |
Биосерокс Продактс Б.В. |
Гуманизированные антитела против cd134 (ox40) и применения указанных антител
|
|
EP3495814A3
(en)
|
2013-03-27 |
2019-07-17 |
F. Hoffmann-La Roche AG |
Use of biomarkers for assessing treatment of gastrointestinal inflammatory disorders with beta7 integrin antagonists
|
|
US20160053023A1
(en)
|
2013-04-09 |
2016-02-25 |
Annexon, Inc. |
Methods of treatment for neuromyelitis optica
|
|
US9206188B2
(en)
|
2013-04-18 |
2015-12-08 |
Arrien Pharmaceuticals Llc |
Substituted pyrrolo[2,3-b]pyridines as ITK and JAK inhibitors
|
|
AU2014262566A1
(en)
|
2013-05-08 |
2015-11-12 |
Zymeworks Inc. |
Bispecific HER2 and HER3 antigen binding constructs
|
|
IL242088B2
(en)
|
2013-05-20 |
2023-12-01 |
Genentech Inc |
Anti-transferrin receptor antibodies and methods of use
|
|
JP2016520199A
(ja)
|
2013-05-24 |
2016-07-11 |
ネステク ソシエテ アノニム |
過敏性腸症候群を診断するための経路特異的マーカー
|
|
US10086054B2
(en)
|
2013-06-26 |
2018-10-02 |
Academia Sinica |
RM2 antigens and use thereof
|
|
US9981030B2
(en)
|
2013-06-27 |
2018-05-29 |
Academia Sinica |
Glycan conjugates and use thereof
|
|
SI3019240T1
(sl)
|
2013-07-09 |
2024-07-31 |
Annexon, Inc. |
Protitelesa proti komplementnemu faktorju C1q in njihova uporaba
|
|
CN105377873B
(zh)
|
2013-07-12 |
2021-03-30 |
豪夫迈·罗氏有限公司 |
阐明离子交换层析输入优化
|
|
EP3022303B1
(en)
*
|
2013-07-17 |
2023-11-01 |
Foundation Medicine, Inc. |
Methods of treating urothelial carcinomas
|
|
CN105814074B
(zh)
|
2013-07-18 |
2020-04-21 |
图鲁斯生物科学有限责任公司 |
具有超长互补决定区的人源化抗体
|
|
WO2015017146A2
(en)
|
2013-07-18 |
2015-02-05 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
|
MX2016001854A
(es)
|
2013-08-12 |
2016-09-06 |
Genentech Inc |
Composiciones y metodo para tratar condiciones asociadas con el complemento.
|
|
RU2016112549A
(ru)
|
2013-09-05 |
2017-10-10 |
Дженентек, Инк. |
Способ для повторного использования хроматографии
|
|
WO2015035337A1
(en)
|
2013-09-06 |
2015-03-12 |
Academia Sinica |
HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS
|
|
KR20160055253A
(ko)
|
2013-09-12 |
2016-05-17 |
할로자임, 아이엔씨 |
변형된 항-상피세포 성장인자 수용체 항체 및 이의 사용 방법
|
|
ES2915378T3
(es)
|
2013-09-13 |
2022-06-22 |
Hoffmann La Roche |
Procedimientos para detectar y cuantificar una proteína de célula huésped en líneas celulares
|
|
KR102571391B1
(ko)
|
2013-09-13 |
2023-08-29 |
제넨테크, 인크. |
정제된 재조합 폴리펩티드를 포함하는 방법 및 조성물
|
|
KR20160055252A
(ko)
|
2013-09-17 |
2016-05-17 |
제넨테크, 인크. |
항-lgr5 항체의 사용 방법
|
|
KR20160055861A
(ko)
|
2013-09-17 |
2016-05-18 |
오비아이 파머 인코퍼레이티드 |
암치료에서 면역반응을 유도하기 위한 탄수화물 백신의 조성물
|
|
US10414818B2
(en)
|
2013-09-27 |
2019-09-17 |
Roche Diagnostics Operations, Inc. |
Thermus thermophilus SlyD FKBP domain specific antibodies
|
|
PT3049441T
(pt)
|
2013-09-27 |
2020-01-21 |
Hoffmann La Roche |
Formulações de anticorpos anti-pdl1
|
|
ES2775579T3
(es)
|
2013-10-04 |
2020-07-27 |
Aptose Biosciences Inc |
Composiciones para el tratamiento del cáncer
|
|
KR20160044060A
(ko)
|
2013-10-11 |
2016-04-22 |
에프. 호프만-라 로슈 아게 |
다중특이적 도메인 교환된 통상의 가변 경쇄 항체
|
|
BR112016007635A2
(pt)
|
2013-10-11 |
2017-09-12 |
Genentech Inc |
inibidores de nsp4 e métodos de uso
|
|
WO2015058132A2
(en)
|
2013-10-18 |
2015-04-23 |
Genentech, Inc. |
Anti-rspo antibodies and methods of use
|
|
BR112016008694A2
(pt)
|
2013-10-23 |
2017-10-03 |
Genentech Inc |
Métodos de previsão da reação de pacientes com asma, de previsão da capacidade de reação de pacientes com asma, de identificação de pacientes com asma, de tratamento de pacientes portadores de asma e de tratamento de asma, uso de um kit e kit
|
|
JP2016538283A
(ja)
|
2013-11-13 |
2016-12-08 |
ザイムワークス,インコーポレイテッド |
Egfr及び/またはher2を標的にする一価抗原結合性構築物及びその使用
|
|
SI3071597T1
(sl)
|
2013-11-21 |
2020-11-30 |
F. Hoffmann-La Roche Ag |
Anti alfa-sinukleinska protitelesa in postopki uporabe
|
|
UA115388C2
(uk)
|
2013-11-21 |
2017-10-25 |
Пфайзер Інк. |
2,6-заміщені пуринові похідні та їх застосування в лікуванні проліферативних захворювань
|
|
ES3030987T3
(en)
|
2013-11-27 |
2025-07-03 |
Zymeworks Bc Inc |
Bispecific antigen-binding constructs targeting her2
|
|
HRP20192052T1
(hr)
|
2013-12-09 |
2020-02-07 |
Allakos Inc. |
Protutijela anti-siglec-8 te njihovi postupci i uporabe
|
|
EP3461845B1
(en)
|
2013-12-13 |
2020-09-16 |
Genentech, Inc. |
Anti-cd33 antibodies and immunoconjugates
|
|
BR112016013963A2
(pt)
|
2013-12-17 |
2017-10-10 |
Genentech Inc |
terapia de combinação compreendendo agonistas de ligação de ox40 e antagonistas de ligação do eixo de pd-1
|
|
PE20210107A1
(es)
|
2013-12-17 |
2021-01-19 |
Genentech Inc |
Anticuerpos anti-cd3 y metodos de uso
|
|
CA2933881A1
(en)
|
2013-12-17 |
2015-06-25 |
Genentech, Inc. |
Methods of treating cancer using pd-1 axis binding antagonists and an anti-cd20 antibody
|
|
FI3083686T4
(fi)
|
2013-12-17 |
2023-05-09 |
|
Menetelmiä syöpien hoitamiseksi käyttäen pd-1-akselia sitovia antagonisteja ja taksaaneja
|
|
MX2016007208A
(es)
|
2013-12-20 |
2016-07-21 |
Hoffmann La Roche |
Anticuerpos anti-tau(ps422) humanizados y metodos de uso.
|
|
TWI728373B
(zh)
|
2013-12-23 |
2021-05-21 |
美商建南德克公司 |
抗體及使用方法
|
|
BR112016014945A2
(pt)
|
2014-01-03 |
2018-01-23 |
F. Hoffmann-La Roche Ag |
conjugado, formulação farmacêutica e uso
|
|
EP3089996B1
(en)
|
2014-01-03 |
2021-07-28 |
F. Hoffmann-La Roche AG |
Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles
|
|
EP3089758B1
(en)
|
2014-01-03 |
2021-01-27 |
F.Hoffmann-La Roche Ag |
Covalently linked helicar-anti-helicar antibody conjugates and uses thereof
|
|
BR112016015589A2
(pt)
|
2014-01-06 |
2017-10-31 |
Hoffmann La Roche |
módulos de trânsito monovalentes para a barreira hematoencefálica
|
|
US10548985B2
(en)
|
2014-01-10 |
2020-02-04 |
Birdie Biopharmaceuticals, Inc. |
Compounds and compositions for treating EGFR expressing tumors
|
|
US9982041B2
(en)
|
2014-01-16 |
2018-05-29 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
WO2016114819A1
(en)
|
2015-01-16 |
2016-07-21 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
SI3097122T1
(sl)
|
2014-01-24 |
2020-07-31 |
Ngm Biopharmaceuticals, Inc. |
Protitelesa, ki se vežejo v domeni beta klotho 2, in metode za njihovo uporabo
|
|
AU2015209154A1
(en)
|
2014-01-24 |
2017-02-16 |
Genentech, Inc. |
Methods of using anti-STEAP1 antibodies and immunoconjugates
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
WO2015116902A1
(en)
|
2014-01-31 |
2015-08-06 |
Genentech, Inc. |
G-protein coupled receptors in hedgehog signaling
|
|
DK3102197T3
(en)
|
2014-02-04 |
2018-11-19 |
Genentech Inc |
Smoothened mutant and methods for its use
|
|
KR102476641B1
(ko)
|
2014-02-08 |
2022-12-09 |
제넨테크, 인크. |
알츠하이머병의 치료 방법
|
|
EP3718563A1
(en)
|
2014-02-08 |
2020-10-07 |
F. Hoffmann-La Roche AG |
Methods of treating alzheimer's disease
|
|
CA2936565C
(en)
|
2014-02-12 |
2020-08-11 |
Genentech, Inc. |
Anti-jagged1 antibodies and methods of use
|
|
MX2016010729A
(es)
|
2014-02-21 |
2016-10-26 |
Genentech Inc |
Anticuerpos biespecificos anti-il-13 / il-17 y sus usos.
|
|
WO2015131155A1
(en)
|
2014-02-28 |
2015-09-03 |
Allakos Inc. |
Methods and compositions for treating siglec-8 associated diseases
|
|
CA2936962C
(en)
|
2014-03-14 |
2024-03-05 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
|
WO2015139046A1
(en)
|
2014-03-14 |
2015-09-17 |
Genentech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
|
ES2939760T3
(es)
|
2014-03-15 |
2023-04-26 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico para antígenos
|
|
BR112016023417A2
(pt)
|
2014-03-21 |
2019-04-16 |
F. Hoffmann-La Roche Ag |
predição in vitro de meia-vida in vivo
|
|
US20170107294A1
(en)
|
2014-03-21 |
2017-04-20 |
Nordlandssykehuset Hf |
Anti-cd14 antibodies and uses thereof
|
|
CN107002119A
(zh)
|
2014-03-24 |
2017-08-01 |
豪夫迈·罗氏有限公司 |
使用c‑met拮抗剂的癌症治疗及前者与hgf表达的关联
|
|
EP3129767B1
(en)
|
2014-03-27 |
2021-09-01 |
Academia Sinica |
Reactive labelling compounds and uses thereof
|
|
SG11201607938UA
(en)
|
2014-03-27 |
2016-10-28 |
Genentech Inc |
Methods for diagnosing and treating inflammatory bowel disease
|
|
PE20161571A1
(es)
|
2014-03-31 |
2017-02-07 |
Genentech Inc |
Anticuerpos anti-ox40 y metodos de uso
|
|
JP6588461B2
(ja)
|
2014-03-31 |
2019-10-09 |
ジェネンテック, インコーポレイテッド |
抗血管新生剤及びox40結合アゴニストを含む併用療法
|
|
WO2015155624A1
(en)
|
2014-04-10 |
2015-10-15 |
Pfizer Inc. |
Dihydropyrrolopyrimidine derivatives
|
|
US20150361163A1
(en)
|
2014-04-18 |
2015-12-17 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating sickle-cell disease
|
|
WO2015164615A1
(en)
|
2014-04-24 |
2015-10-29 |
University Of Oslo |
Anti-gluten antibodies and uses thereof
|
|
AU2015249946A1
(en)
|
2014-04-25 |
2016-11-17 |
The Brigham And Women's Hospital Inc. |
Methods to manipulate alpha-fetoprotein (AFP)
|
|
CR20160497A
(es)
|
2014-04-30 |
2016-12-20 |
Pfizer |
Derivados de diheterociclo enlazado a cicloalquilo
|
|
EA201692109A1
(ru)
|
2014-05-01 |
2017-03-31 |
Дженентек, Инк. |
Варианты антител к фактору d и их применение
|
|
JP6875129B2
(ja)
|
2014-05-08 |
2021-05-19 |
ノボダイアックス, インコーポレイテッド |
直接的な免疫組織化学アッセイ
|
|
EP3145952A2
(en)
|
2014-05-22 |
2017-03-29 |
Genentech, Inc. |
Anti-gpc3 antibodies and immunoconjugates
|
|
KR20170005016A
(ko)
|
2014-05-23 |
2017-01-11 |
제넨테크, 인크. |
MiT 바이오마커 및 그의 사용 방법
|
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
|
CN106573971A
(zh)
|
2014-05-27 |
2017-04-19 |
中央研究院 |
抗cd20醣抗体及其用途
|
|
CA2950440A1
(en)
|
2014-05-27 |
2015-12-03 |
Academia Sinica |
Anti-her2 glycoantibodies and uses thereof
|
|
AU2015267051B2
(en)
|
2014-05-27 |
2022-03-17 |
Academia Sinica |
Fucosidase from bacteroides and methods using the same
|
|
CN106714829A
(zh)
|
2014-05-28 |
2017-05-24 |
中央研究院 |
抗TNF‑α醣抗体及其用途
|
|
MX2016016233A
(es)
|
2014-06-11 |
2017-03-31 |
Genentech Inc |
Anticuerpos anti-lgr5 y sus usos.
|
|
JP2017517552A
(ja)
|
2014-06-13 |
2017-06-29 |
ジェネンテック, インコーポレイテッド |
抗癌剤耐性の治療及び防止方法
|
|
MA40008A
(fr)
|
2014-06-13 |
2021-05-05 |
Acceleron Pharma Inc |
Antagoniste actrii pour le traitement et la prevention d'un ulcere cutane chez un sujet ayant l'anemie
|
|
CA2947504A1
(en)
|
2014-06-26 |
2015-12-30 |
F. Hoffmann-La Roche Ag |
Anti-brdu antibodies and methods of use
|
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
|
WO2016001789A1
(en)
|
2014-06-30 |
2016-01-07 |
Pfizer Inc. |
Pyrimidine derivatives as pi3k inhibitors for use in the treatment of cancer
|
|
SI3164492T1
(sl)
|
2014-07-03 |
2020-02-28 |
F. Hoffmann-La Roche Ag |
Sistem polipeptidne ekspresije
|
|
EP3164194B1
(en)
|
2014-07-03 |
2021-11-24 |
Yale University |
Dickkopf2 (dkk2) inhibition suppresses tumor formation
|
|
CA2954446A1
(en)
|
2014-07-09 |
2016-01-14 |
Shanghai Birdie Biotech, Inc. |
Anti-pd-l1 combinations for treating tumors
|
|
CN105440135A
(zh)
|
2014-09-01 |
2016-03-30 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
|
CN112546231A
(zh)
|
2014-07-09 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗癌症的联合治疗组合物和联合治疗方法
|
|
BR112017000130A2
(pt)
|
2014-07-11 |
2018-01-09 |
Genentech Inc |
método para atenuar a toxicidade associada à inibição da via de notch e método de tratamento do câncer
|
|
BR112017000497B1
(pt)
|
2014-07-11 |
2023-12-26 |
Ventana Medical Systems, Inc |
Anticorpo isolado, célula hospedeira procariótica, imunoconjugado e método de detecção da presença ou do nível de expressão de pd-l1
|
|
JP7054622B2
(ja)
|
2014-07-21 |
2022-04-14 |
ノバルティス アーゲー |
ヒト化抗bcmaキメラ抗原受容体を使用した癌の処置
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
JP2017528433A
(ja)
|
2014-07-21 |
2017-09-28 |
ノバルティス アーゲー |
低い免疫増強用量のmTOR阻害剤とCARの組み合わせ
|
|
EP3722316A1
(en)
|
2014-07-21 |
2020-10-14 |
Novartis AG |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
ES2781175T3
(es)
|
2014-07-31 |
2020-08-31 |
Novartis Ag |
Subconjunto optimizado de células T que contienen un receptor de antígeno quimérico
|
|
DK3177643T3
(da)
|
2014-08-04 |
2019-07-15 |
Hoffmann La Roche |
Bispecifikke T-celle-aktiverende antigenbindende molekyler
|
|
MX2017001531A
(es)
|
2014-08-08 |
2017-05-15 |
Alector Llc |
Anticuerpos anti-trem2 y metodos de uso de los mismos.
|
|
US10851149B2
(en)
|
2014-08-14 |
2020-12-01 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using GFR α-4 chimeric antigen receptor
|
|
ES2791248T3
(es)
|
2014-08-19 |
2020-11-03 |
Novartis Ag |
Receptor antigénico quimérico (CAR) anti-CD123 para su uso en el tratamiento del cáncer
|
|
DK3186281T3
(da)
|
2014-08-28 |
2019-06-11 |
Halozyme Inc |
Kombinationsterapi med et hyaluronan-nedbrydende enzym og en immun-checkpoint-inhibitor
|
|
RU2764074C2
(ru)
|
2014-08-28 |
2022-01-13 |
Байоатла, Ллк |
Условно активные химерные антигенные рецепторы для модифицированных т-клеток
|
|
US9879042B2
(en)
|
2014-09-08 |
2018-01-30 |
Academia Sinica |
Human iNKT cell activation using glycolipids
|
|
EP3388449A3
(en)
|
2014-09-12 |
2018-10-24 |
F. Hoffmann-La Roche AG |
Cysteine engineered antibodies and conjugates
|
|
EP3191518B1
(en)
|
2014-09-12 |
2020-01-15 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
|
US9751946B2
(en)
|
2014-09-12 |
2017-09-05 |
Genentech, Inc. |
Anti-CLL-1 antibodies and immunoconjugates
|
|
KR102508173B1
(ko)
|
2014-09-12 |
2023-03-10 |
제넨테크, 인크. |
항-her2 항체 및 면역콘주게이트
|
|
EP3193932B1
(en)
|
2014-09-15 |
2023-04-26 |
F. Hoffmann-La Roche AG |
Antibody formulations
|
|
HK1243629A1
(zh)
|
2014-09-17 |
2018-07-20 |
基因泰克公司 |
包含抗her2抗体和吡咯并苯并二氮杂䓬的免疫缀合物
|
|
US10577417B2
(en)
|
2014-09-17 |
2020-03-03 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
EP3689910A3
(en)
|
2014-09-23 |
2020-12-02 |
F. Hoffmann-La Roche AG |
Method of using anti-cd79b immunoconjugates
|
|
US10428143B2
(en)
|
2014-09-28 |
2019-10-01 |
The Regents Of The University Of California |
Modulation of stimulatory and non-stimulatory myeloid cells
|
|
CA2964367C
(en)
|
2014-10-14 |
2024-01-30 |
Novartis Ag |
Antibody molecules to pd-l1 and uses thereof
|
|
CN107074938A
(zh)
|
2014-10-16 |
2017-08-18 |
豪夫迈·罗氏有限公司 |
抗‑α‑突触核蛋白抗体和使用方法
|
|
CA2966523A1
(en)
|
2014-11-03 |
2016-05-12 |
Genentech, Inc. |
Assays for detecting t cell immune subsets and methods of use thereof
|
|
SG11201703521UA
(en)
|
2014-11-03 |
2017-05-30 |
Genentech Inc |
Methods and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment
|
|
KR20170080675A
(ko)
|
2014-11-05 |
2017-07-10 |
제넨테크, 인크. |
항-fgfr2/3 항체 및 이의 이용 방법
|
|
RU2739500C2
(ru)
|
2014-11-05 |
2020-12-25 |
Дженентек, Инк. |
Способы получения двуцепочечных белков в бактериях
|
|
SG11201703667SA
(en)
|
2014-11-05 |
2017-06-29 |
Annexon Inc |
Humanized anti-complement factor c1q antibodies and uses thereof
|
|
CN108064308B
(zh)
|
2014-11-05 |
2023-06-09 |
豪夫迈·罗氏有限公司 |
细菌中产生双链蛋白的方法
|
|
WO2016073157A1
(en)
|
2014-11-06 |
2016-05-12 |
Genentech, Inc. |
Anti-ang2 antibodies and methods of use thereof
|
|
KR20170072343A
(ko)
|
2014-11-06 |
2017-06-26 |
제넨테크, 인크. |
Ox40 결합 효능제 및 tigit 억제제를 포함하는 병용 요법
|
|
EP3552488A1
(en)
|
2014-11-10 |
2019-10-16 |
F. Hoffmann-La Roche AG |
Animal model for nephropathy and agents for treating the same
|
|
MX2017006094A
(es)
|
2014-11-10 |
2017-07-19 |
Genentech Inc |
Anticuerpos anti-interleucina-33 y sus usos.
|
|
TWI757803B
(zh)
|
2014-11-14 |
2022-03-11 |
瑞士商赫孚孟拉羅股份公司 |
包含tnf家族配位三聚體之抗原結合分子
|
|
EP3221360A1
(en)
|
2014-11-17 |
2017-09-27 |
F. Hoffmann-La Roche AG |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
|
CN107108745B
(zh)
|
2014-11-19 |
2021-01-12 |
基因泰克公司 |
抗bace1的抗体和其用于神经疾病免疫疗法的用途
|
|
US10508151B2
(en)
|
2014-11-19 |
2019-12-17 |
Genentech, Inc. |
Anti-transferrin receptor antibodies and methods of use
|
|
CA2968338A1
(en)
|
2014-11-19 |
2016-05-26 |
Nestec S.A. |
Antibodies against serotonin, tryptophan and kynurenine metabolites and uses thereof
|
|
JP6993228B2
(ja)
|
2014-11-19 |
2022-03-03 |
ジェネンテック, インコーポレイテッド |
抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法
|
|
DK3221356T3
(da)
|
2014-11-20 |
2020-11-02 |
Hoffmann La Roche |
T-celleaktiverende, bispecifikke, antigenbindende molekyler mod folr1 og cd3
|
|
DK4141032T3
(da)
|
2014-11-20 |
2024-08-05 |
Hoffmann La Roche |
Kombinationsbehandling med T-celleaktiverende bispecifikke antigenbindende molekyler og PD-1-aksebindende antagonister
|
|
DK3221357T3
(da)
|
2014-11-20 |
2020-08-10 |
Hoffmann La Roche |
Fælles letkæder og fremgangsmåder til anvendelse
|
|
DK3223848T3
(da)
|
2014-11-27 |
2025-03-03 |
Zymeworks Bc Inc |
Fremgangsmåder til anvendelse af bispecifikke antigenbindingskonstrukter målrettet her2
|
|
WO2016087514A1
(en)
|
2014-12-02 |
2016-06-09 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Anti-mutant calreticulin antibodies and their use in the diagnosis and therapy of myeloid malignancies
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
MA41119A
(fr)
|
2014-12-03 |
2017-10-10 |
Acceleron Pharma Inc |
Méthodes de traitement de syndromes myélodysplasiques et d'anémie sidéroblastique
|
|
WO2016087416A1
(en)
|
2014-12-03 |
2016-06-09 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
SG11201704449VA
(en)
|
2014-12-05 |
2017-06-29 |
Genentech Inc |
ANTI-CD79b ANTIBODIES AND METHODS OF USE
|
|
EP3230317A2
(en)
|
2014-12-10 |
2017-10-18 |
F. Hoffmann-La Roche AG |
Blood brain barrier receptor antibodies and methods of use
|
|
US20160168237A1
(en)
|
2014-12-12 |
2016-06-16 |
Alexion Pharmaceuticals, Inc. |
Method for treating a complement mediated disorder caused by an infectious agent in a patient
|
|
WO2016097918A1
(en)
|
2014-12-18 |
2016-06-23 |
Pfizer Inc. |
Pyrimidine and triazine derivatives and their use as axl inhibitors
|
|
EP3034130B1
(en)
|
2014-12-19 |
2019-12-04 |
Althia Health, S.L. |
Monoclonal antibody for the diagnosis, treatment and/or prevention of brain tumors and brain lesions
|
|
IL278014B2
(en)
|
2014-12-19 |
2023-10-01 |
Chugai Pharmaceutical Co Ltd |
Anti-myostatin antibodies, polypeptides containing variable FC regions and methods of use
|
|
AR103162A1
(es)
|
2014-12-19 |
2017-04-19 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos anti-c5 y métodos para su uso
|
|
HK1245134A1
(zh)
|
2015-01-14 |
2018-08-24 |
The Brigham And Women's Hospital, Inc. |
用抗lap单克隆抗体治疗癌症
|
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
|
JP2018511557A
(ja)
|
2015-01-22 |
2018-04-26 |
中外製薬株式会社 |
2種以上の抗c5抗体の組み合わせおよび使用方法
|
|
AU2015378564A1
(en)
|
2015-01-24 |
2017-07-13 |
Academia Sinica |
Novel glycan conjugates and methods of use thereof
|
|
CA2972731A1
(en)
|
2015-01-24 |
2016-07-28 |
Chi-Huey Wong |
Cancer markers and methods of use thereof
|
|
JP2018506275A
(ja)
|
2015-01-28 |
2018-03-08 |
ジェネンテック, インコーポレイテッド |
多発性硬化症の遺伝子発現マーカー及び治療
|
|
EP3250590B1
(en)
|
2015-01-30 |
2021-09-15 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced anti-ssea4 antibody efficacy
|
|
CA2975875A1
(en)
|
2015-02-04 |
2016-08-11 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
|
SG10201907215QA
(en)
|
2015-02-05 |
2019-09-27 |
Chugai Pharmaceutical Co Ltd |
Antibodies Comprising An Ion Concentration Dependent Antigen-Binding Domain, Fc Region Variants, Il-8-Binding Antibodies, And Uses Therof
|
|
JP6959869B2
(ja)
|
2015-02-23 |
2021-11-05 |
シーガル セラピューティクス エスアーエス |
非天然セマフォリン3およびそれらの医学的使用
|
|
EP3262072A1
(en)
|
2015-02-26 |
2018-01-03 |
F. Hoffmann-La Roche AG |
Integrin beta7 antagonists and methods of treating crohn's disease
|
|
CN107531749A
(zh)
|
2015-03-06 |
2018-01-02 |
豪夫迈·罗氏有限公司 |
超纯化DsbA和DsbC及其制备和使用方法
|
|
CA2977285A1
(en)
|
2015-03-16 |
2016-09-22 |
F. Hoffmann-La Roche Ag |
Methods of detecting and quantifying il-13 and uses in diagnosing and treating th2-associated diseases
|
|
WO2016145536A1
(en)
|
2015-03-18 |
2016-09-22 |
Immunobiochem Corporation |
Conjugates for the treatment of cancer targeted at intracellular tumor-associated antigens
|
|
WO2016146833A1
(en)
|
2015-03-19 |
2016-09-22 |
F. Hoffmann-La Roche Ag |
Biomarkers for nad(+)-diphthamide adp ribosyltransferase resistance
|
|
MA41919A
(fr)
|
2015-04-06 |
2018-02-13 |
Acceleron Pharma Inc |
Hétéromultimères alk4:actriib et leurs utilisations
|
|
EP3828199B1
(en)
|
2015-04-06 |
2025-10-15 |
Acceleron Pharma Inc. |
Alk7: actriib heteromultimers and uses thereof
|
|
KR20180002653A
(ko)
|
2015-04-07 |
2018-01-08 |
제넨테크, 인크. |
효능작용 활성을 갖는 항원 결합 복합체 및 사용 방법
|
|
JP6999421B2
(ja)
|
2015-04-07 |
2022-02-04 |
アレクトル エルエルシー |
抗ソルチリン抗体及びその使用方法
|
|
JP6961490B2
(ja)
|
2015-04-08 |
2021-11-05 |
ノバルティス アーゲー |
Cd20療法、cd22療法、およびcd19キメラ抗原受容体(car)発現細胞との併用療法
|
|
WO2016172214A1
(en)
|
2015-04-20 |
2016-10-27 |
Tolero Pharmaceuticals, Inc. |
Predicting response to alvocidib by mitochondrial profiling
|
|
ES3007999T3
(en)
|
2015-04-21 |
2025-03-21 |
Genentech Inc |
Compositions and methods for prostate cancer analysis
|
|
GB201506870D0
(en)
|
2015-04-22 |
2015-06-03 |
Ucb Biopharma Sprl |
Method
|
|
US12128069B2
(en)
|
2015-04-23 |
2024-10-29 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
CN115932273A
(zh)
|
2015-04-24 |
2023-04-07 |
豪夫迈·罗氏有限公司 |
鉴定包含结合多肽的细菌的方法
|
|
EP3288957A4
(en)
|
2015-05-01 |
2019-01-23 |
Cocrystal Pharma, Inc. |
NUCLEOSIDE ANALOGUE FOR THE TREATMENT OF VIRUSES OF THE FLAVIVIIDAE FAMILY AND CANCER
|
|
CN107709363A
(zh)
|
2015-05-01 |
2018-02-16 |
基因泰克公司 |
掩蔽抗cd3抗体和使用方法
|
|
EP4238994A3
(en)
|
2015-05-11 |
2024-02-07 |
F. Hoffmann-La Roche AG |
Compositions and methods of treating lupus nephritis
|
|
RS61152B2
(sr)
|
2015-05-12 |
2024-06-28 |
Hoffmann La Roche |
Terapeutski i dijagnostički postupci za lečenje raka
|
|
RU2752729C2
(ru)
|
2015-05-18 |
2021-07-30 |
Сумитомо Даиниппон Фарма Онколоджи, Инк. |
Пролекарства альвоцидиба, имеющие повышенную биодоступность
|
|
CN107646038B
(zh)
|
2015-05-28 |
2021-08-20 |
基因泰克公司 |
用于检测抗cd3同二聚体的基于细胞的测定
|
|
HK1248773A1
(zh)
|
2015-05-29 |
2018-10-19 |
豪夫迈‧罗氏有限公司 |
用於癌症的治疗和诊断方法
|
|
AU2016271142A1
(en)
|
2015-05-29 |
2017-11-23 |
Genentech, Inc. |
PD-L1 promoter methylation in cancer
|
|
WO2016196343A1
(en)
|
2015-05-29 |
2016-12-08 |
Genentech, Inc. |
Humanized anti-ebola virus glycoprotein antibodies and methods of use
|
|
US20180153884A1
(en)
|
2015-05-31 |
2018-06-07 |
Curegenix Corporation |
Combination compositions for immunotherapy
|
|
JP2018516933A
(ja)
|
2015-06-02 |
2018-06-28 |
ジェネンテック, インコーポレイテッド |
抗il−34抗体を使用して神経学的疾患を治療するための組成物及び方法
|
|
EP4465050A3
(en)
|
2015-06-05 |
2025-06-11 |
Genentech, Inc. |
Anti-tau antibodies and methods of use
|
|
JP2018521019A
(ja)
|
2015-06-08 |
2018-08-02 |
ジェネンテック, インコーポレイテッド |
抗ox40抗体を使用して癌を治療する方法
|
|
JP2018518483A
(ja)
|
2015-06-08 |
2018-07-12 |
ジェネンテック, インコーポレイテッド |
抗ox40抗体及びpd−1軸結合アンタゴニストを使用して癌を治療する方法
|
|
AU2016276981B2
(en)
|
2015-06-12 |
2022-10-06 |
Alector Llc |
Anti-CD33 antibodies and methods of use thereof
|
|
WO2016201389A2
(en)
|
2015-06-12 |
2016-12-15 |
Alector Llc |
Anti-cd33 antibodies and methods of use thereof
|
|
JP2018524295A
(ja)
|
2015-06-15 |
2018-08-30 |
ジェネンテック, インコーポレイテッド |
抗体及び免疫複合体
|
|
EP3310378B1
(en)
|
2015-06-16 |
2024-01-24 |
F. Hoffmann-La Roche AG |
Anti-cll-1 antibodies and methods of use
|
|
CN107849132B
(zh)
|
2015-06-16 |
2022-03-08 |
豪夫迈·罗氏有限公司 |
人源化的和亲和力成熟的针对FcRH5的抗体和使用方法
|
|
EP3916018A1
(en)
|
2015-06-16 |
2021-12-01 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
|
IL256080B2
(en)
|
2015-06-17 |
2025-06-01 |
Genentech Inc |
Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes
|
|
JP2018524312A
(ja)
|
2015-06-17 |
2018-08-30 |
ジェネンテック, インコーポレイテッド |
抗her2抗体及び使用方法
|
|
WO2016205567A1
(en)
|
2015-06-17 |
2016-12-22 |
Allakos Inc. |
Methods and compositions for treating fibrotic diseases
|
|
CN113929779B
(zh)
|
2015-06-24 |
2025-02-25 |
豪夫迈·罗氏有限公司 |
人源化的抗-Tau(pS422)抗体和使用方法
|
|
EP3514174B1
(en)
|
2015-06-29 |
2021-03-31 |
Ventana Medical Systems, Inc. |
Materials and methods for performing histochemical assays for human pro-epiregulin and amphiregulin
|
|
CA2989936A1
(en)
|
2015-06-29 |
2017-01-05 |
Genentech, Inc. |
Type ii anti-cd20 antibody for use in organ transplantation
|
|
WO2017009751A1
(en)
|
2015-07-15 |
2017-01-19 |
Pfizer Inc. |
Pyrimidine derivatives
|
|
US20180207273A1
(en)
|
2015-07-29 |
2018-07-26 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
|
WO2017019896A1
(en)
|
2015-07-29 |
2017-02-02 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
DK3317301T3
(da)
|
2015-07-29 |
2021-06-28 |
Immutep Sas |
Kombinationsterapier omfattende antistofmolekyler mod lag-3
|
|
JP7083497B2
(ja)
|
2015-08-03 |
2022-06-13 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
がんの処置のための併用療法
|
|
EP3331550B1
(en)
|
2015-08-04 |
2022-11-02 |
Acceleron Pharma Inc. |
Composition for treating myeloproliferative disorders
|
|
TW202440903A
(zh)
|
2015-08-04 |
2024-10-16 |
美商再生元醫藥公司 |
補充牛磺酸之細胞培養基及用法(一)
|
|
CN108136012B
(zh)
|
2015-08-07 |
2022-10-04 |
伊麦吉纳博公司 |
靶向分子的抗原结合构建体
|
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
|
WO2017040301A1
(en)
|
2015-08-28 |
2017-03-09 |
Alector Llc |
Anti-siglec-7 antibodies and methods of use thereof
|
|
EP3932953A1
(en)
|
2015-08-28 |
2022-01-05 |
F. Hoffmann-La Roche AG |
Anti-hypusine antibodies and uses thereof
|
|
KR20180050339A
(ko)
|
2015-09-04 |
2018-05-14 |
오비아이 파머 인코퍼레이티드 |
글리칸 어레이 및 사용 방법
|
|
EP3328885A1
(en)
|
2015-09-11 |
2018-06-06 |
Bruce Andrien |
Recombinant glycosylated eculizumab and eculizumab variants
|
|
MY203894A
(en)
|
2015-09-18 |
2024-07-23 |
Chugai Pharmaceutical Co Ltd |
Il-8-binding antibodies and uses thereof
|
|
JP6904947B2
(ja)
|
2015-09-22 |
2021-07-21 |
スプリング バイオサイエンス コーポレーション |
抗ox40抗体及びその診断用途
|
|
KR102725051B1
(ko)
|
2015-09-23 |
2024-11-04 |
제넨테크, 인크. |
항-vegf 항체의 최적화된 변이체들
|
|
KR20230125094A
(ko)
|
2015-09-25 |
2023-08-28 |
제넨테크, 인크. |
항-tigit 항체 및 이의 이용 방법
|
|
WO2017058881A1
(en)
|
2015-09-28 |
2017-04-06 |
The Trustees Of Columbia University In The City Of New York |
Use of pentoxifylline with immune checkpoint-blockade therapies for the treatment of melanoma
|
|
EP3355920A4
(en)
|
2015-09-29 |
2019-05-15 |
Celgene Corporation |
PD-1 BINDING PROTEINS AND METHOD OF USE THEREOF
|
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
|
WO2017055314A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Bispecific anti-cd19xcd3 t cell activating antigen binding molecules
|
|
KR20180073561A
(ko)
|
2015-10-02 |
2018-07-02 |
에프. 호프만-라 로슈 아게 |
이중특이적 항-ceaxcd3 t 세포 활성화 항원 결합 분자
|
|
WO2017055385A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xgd2 bispecific t cell activating antigen binding molecules
|
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
|
KR20180053674A
(ko)
|
2015-10-02 |
2018-05-23 |
에프. 호프만-라 로슈 아게 |
공자극 tnf 수용체에 특이적인 이중특이성 항체
|
|
WO2017055393A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xtim-3 bispecific t cell activating antigen binding molecules
|
|
WO2017055392A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xcd44v6 bispecific t cell activating antigen binding molecules
|
|
WO2017055395A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xrob04 bispecific t cell activating antigen binding molecules
|
|
CN107949574A
(zh)
|
2015-10-02 |
2018-04-20 |
豪夫迈·罗氏有限公司 |
双特异性t细胞活化性抗原结合分子
|
|
RS62258B1
(sr)
|
2015-10-02 |
2021-09-30 |
Hoffmann La Roche |
Bispecifična antitela specifična za pd1 i tim3
|
|
MA43018B1
(fr)
|
2015-10-02 |
2021-11-30 |
Hoffmann La Roche |
Anticorps anti-pd1 et procédés d'utilisation
|
|
WO2017055391A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Bispecific t cell activating antigen binding molecules binding mesothelin and cd3
|
|
HUE069935T2
(hu)
|
2015-10-06 |
2025-04-28 |
Hoffmann La Roche |
Módszer szklerózis multiplex kezelésére
|
|
JP7725185B2
(ja)
|
2015-10-06 |
2025-08-19 |
アレクトル エルエルシー |
抗trem2抗体及びその使用方法
|
|
US11203634B2
(en)
|
2015-10-07 |
2021-12-21 |
Alexion Pharmaceuticals, Inc. |
Methods of treating age-related macular degeneration in a patient comprising administering an anti-C5a antibody
|
|
EP3359568B1
(en)
|
2015-10-07 |
2022-03-09 |
F. Hoffmann-La Roche AG |
Bispecific antibodies with tetravalency for a costimulatory tnf receptor
|
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
|
MA45326A
(fr)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
|
|
US10604577B2
(en)
|
2015-10-22 |
2020-03-31 |
Allakos Inc. |
Methods and compositions for treating systemic mastocytosis
|
|
US10954500B2
(en)
|
2015-10-23 |
2021-03-23 |
Fred Hutchinson Cancer Research Center |
Methods to create chemically-induced dimerizing protein systems for regulation of cellular events
|
|
AU2016344459B2
(en)
|
2015-10-28 |
2023-10-05 |
Yale University |
Humanized anti-DKK2 antibody and uses thereof
|
|
KR20180084817A
(ko)
|
2015-10-29 |
2018-07-25 |
알렉터 엘엘씨 |
항-siglec-9 항체 및 이의 이용 방법
|
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
|
JP6949016B2
(ja)
|
2015-10-29 |
2021-10-13 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
抗バリアントFc領域抗体および使用法
|
|
RU2750285C2
(ru)
|
2015-10-30 |
2021-06-25 |
Дженентек, Инк. |
АНТИТЕЛА ПРОТИВ НtrА1 И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
|
JP2018536650A
(ja)
|
2015-10-30 |
2018-12-13 |
ジェネンテック, インコーポレイテッド |
抗d因子抗体変異体コンジュゲート及びその使用
|
|
WO2017075173A2
(en)
|
2015-10-30 |
2017-05-04 |
Genentech, Inc. |
Anti-factor d antibodies and conjugates
|
|
WO2017079591A2
(en)
|
2015-11-04 |
2017-05-11 |
Acceleron Pharma Inc. |
Methods for increasing red blood cell levels and treating ineffective erythropoiesis
|
|
CN108602884B
(zh)
|
2015-11-08 |
2024-06-25 |
豪夫迈·罗氏有限公司 |
筛选多特异性抗体的方法
|
|
CN106729743B
(zh)
|
2015-11-23 |
2021-09-21 |
四川科伦博泰生物医药股份有限公司 |
抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用
|
|
AU2016359695A1
(en)
|
2015-11-23 |
2018-06-14 |
Acceleron Pharma Inc. |
Methods for treating eye disorders
|
|
JP6877429B2
(ja)
|
2015-12-03 |
2021-05-26 |
アジオス ファーマシューティカルズ, インコーポレイテッド |
Mtapヌル癌を処置するためのmat2a阻害剤
|
|
KR102850929B1
(ko)
|
2015-12-09 |
2025-08-27 |
에프. 호프만-라 로슈 아게 |
항-약물 항체의 형성을 감소시키기 위한 ii형 항-cd20 항체
|
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
|
AU2016370591C1
(en)
|
2015-12-15 |
2020-09-03 |
Gilead Sciences, Inc. |
Human immunodeficiency virus neutralizing antibodies
|
|
WO2017106656A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
|
KR20180094977A
(ko)
|
2015-12-17 |
2018-08-24 |
노파르티스 아게 |
c-Met 억제제와 PD-1에 대한 항체 분자의 조합물 및 그의 용도
|
|
CA3002422C
(en)
|
2015-12-18 |
2024-04-16 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
|
|
IL259256B2
(en)
|
2015-12-18 |
2023-02-01 |
Chugai Pharmaceutical Co Ltd |
Anti-c5 antibodies and methods of use
|
|
EP3393504B1
(en)
|
2015-12-22 |
2025-09-24 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
|
AU2016380988B2
(en)
|
2015-12-30 |
2022-07-21 |
Genentech, Inc. |
Formulations with reduced degradation of polysorbate
|
|
US20170239355A1
(en)
|
2015-12-30 |
2017-08-24 |
Genentech, Inc. |
Use of tryptophan derivatives for protein formulations
|
|
US20200270365A1
(en)
|
2016-01-05 |
2020-08-27 |
Jiangsu Hengrui Medicine Co., Ltd. |
Pcsk9 antibody, antigen-binding fragment thereof, and medical uses thereof
|
|
ES2837428T3
(es)
|
2016-01-08 |
2021-06-30 |
Hoffmann La Roche |
Procedimientos de tratamiento de cánceres positivos para CEA usando antagonistas de unión al eje PD-1 y anticuerpos biespecíficos anti-CEA/anti-CD3
|
|
CN114019170A
(zh)
|
2016-01-20 |
2022-02-08 |
基因泰克公司 |
用于阿尔茨海默氏病的高剂量治疗
|
|
US20210198368A1
(en)
|
2016-01-21 |
2021-07-01 |
Novartis Ag |
Multispecific molecules targeting cll-1
|
|
WO2017132279A1
(en)
|
2016-01-25 |
2017-08-03 |
Genentech, Inc. |
Methods for assaying t-cell dependent bispecific antibodies
|
|
JP2019509721A
(ja)
|
2016-02-04 |
2019-04-11 |
キュリス,インコーポレイテッド |
突然変異体スムースンド及びその使用方法
|
|
US10982136B2
(en)
|
2016-02-26 |
2021-04-20 |
The Regents Of The University Of California |
Ligand-sensitized lanthanide nanocrystals as ultraviolet downconverters
|
|
KR102500659B1
(ko)
|
2016-02-29 |
2023-02-16 |
제넨테크, 인크. |
암에 대한 치료 및 진단 방법
|
|
WO2017149515A1
(en)
|
2016-03-04 |
2017-09-08 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
|
US11472877B2
(en)
|
2016-03-04 |
2022-10-18 |
Alector Llc |
Anti-TREM1 antibodies and methods of use thereof
|
|
EP3216458A1
(en)
|
2016-03-07 |
2017-09-13 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Modified vascular endothelial growth factor a (vegf-a) and its medical use
|
|
KR20180114210A
(ko)
|
2016-03-08 |
2018-10-17 |
아카데미아 시니카 |
N-글리칸의 모듈 합성 방법 및 그의 어레이
|
|
EP3430054B1
(en)
|
2016-03-15 |
2021-12-29 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of treating cancers using pd-1 axis binding antagonists and anti-gpc3 antibodies
|
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
|
JP7015244B2
(ja)
|
2016-03-22 |
2022-02-02 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
プロテアーゼ活性化t細胞二重特異性分子
|
|
PE20181891A1
(es)
|
2016-03-22 |
2018-12-11 |
Hoffmann La Roche |
Moleculas biespecificas de celulas t activadas por proteasas
|
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
|
CN108700598A
(zh)
|
2016-03-25 |
2018-10-23 |
豪夫迈·罗氏有限公司 |
多路总抗体和抗体缀合的药物量化测定法
|
|
EP3231813A1
(en)
|
2016-03-29 |
2017-10-18 |
F. Hoffmann-La Roche AG |
Trimeric costimulatory tnf family ligand-containing antigen binding molecules
|
|
US11041017B2
(en)
|
2016-03-29 |
2021-06-22 |
Obi Pharma, Inc. |
Antibodies, pharmaceutical compositions and methods
|
|
US10980894B2
(en)
|
2016-03-29 |
2021-04-20 |
Obi Pharma, Inc. |
Antibodies, pharmaceutical compositions and methods
|
|
US20170306027A1
(en)
|
2016-04-06 |
2017-10-26 |
Acceleron Pharma Inc. |
Alk7 antagonists and uses thereof
|
|
US20170319688A1
(en)
|
2016-04-14 |
2017-11-09 |
Genentech, Inc. |
Anti-rspo3 antibodies and methods of use
|
|
CN109563164A
(zh)
|
2016-04-15 |
2019-04-02 |
生物蛋白有限公司 |
抗axl抗体、抗体片段和它们的免疫缀合物以及其用途
|
|
JP7503887B2
(ja)
|
2016-04-15 |
2024-06-21 |
ジェネンテック, インコーポレイテッド |
がんを監視及び治療するための方法
|
|
CA3020718A1
(en)
|
2016-04-15 |
2017-10-19 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
|
EP3443096B1
(en)
|
2016-04-15 |
2023-03-01 |
Novartis AG |
Compositions and methods for selective expression of chimeric antigen receptors
|
|
AU2017252128B2
(en)
|
2016-04-22 |
2024-06-06 |
Obi Pharma, Inc. |
Cancer immunotherapy by immune activation or immune modulation via Globo series antigens
|
|
CR20180509A
(es)
|
2016-05-02 |
2019-02-15 |
Hoffmann La Roche |
Contorsbody - un ligante de diana monocatenario
|
|
US20190151346A1
(en)
|
2016-05-10 |
2019-05-23 |
INSERM (Institute National de la Santé et de la Recherche Médicale) |
Combinations therapies for the treatment of cancer
|
|
EP3243836A1
(en)
|
2016-05-11 |
2017-11-15 |
F. Hoffmann-La Roche AG |
C-terminally fused tnf family ligand trimer-containing antigen binding molecules
|
|
JP7089483B2
(ja)
|
2016-05-11 |
2022-06-22 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
修飾された抗テネイシン抗体及び使用方法
|
|
WO2017194442A1
(en)
|
2016-05-11 |
2017-11-16 |
F. Hoffmann-La Roche Ag |
Antigen binding molecules comprising a tnf family ligand trimer and a tenascin binding moiety
|
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
|
TWI844509B
(zh)
|
2016-05-13 |
2024-06-11 |
美商拜奧亞特拉公司 |
抗-ror2抗體、抗體片段、其免疫結合物及其用途
|
|
AU2017268234A1
(en)
|
2016-05-17 |
2018-12-13 |
Genentech, Inc. |
Stromal gene signatures for diagnosis and use in immunotherapy
|
|
CN109152843A
(zh)
|
2016-05-20 |
2019-01-04 |
豪夫迈·罗氏有限公司 |
Protac抗体缀合物及其使用方法
|
|
CN109313200B
(zh)
|
2016-05-27 |
2022-10-04 |
豪夫迈·罗氏有限公司 |
用于表征位点特异性抗体-药物缀合物的生物分析性方法
|
|
AU2018276419A1
(en)
|
2016-06-02 |
2019-10-17 |
F. Hoffmann-La Roche Ag |
Type II anti-CD20 antibody and anti-CD20/CD3 bispecific antibody for treatment of cancer
|
|
EP3464354B1
(en)
|
2016-06-02 |
2021-07-28 |
Bloom Diagnostics AG |
Antibodies that bind to human anti-müllerian hormone (amh) and their uses
|
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
|
US20210177896A1
(en)
|
2016-06-02 |
2021-06-17 |
Novartis Ag |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
US10639378B2
(en)
|
2016-06-06 |
2020-05-05 |
Genentech, Inc. |
Silvestrol antibody-drug conjugates and methods of use
|
|
KR20250107275A
(ko)
|
2016-06-17 |
2025-07-11 |
제넨테크, 인크. |
다중 특이적 항체의 정제
|
|
KR102376582B1
(ko)
|
2016-06-17 |
2022-03-18 |
추가이 세이야쿠 가부시키가이샤 |
항-마이오스타틴 항체 및 사용 방법
|
|
WO2017223405A1
(en)
|
2016-06-24 |
2017-12-28 |
Genentech, Inc. |
Anti-polyubiquitin multispecific antibodies
|
|
WO2018011691A1
(en)
|
2016-07-12 |
2018-01-18 |
Nestec S.A. |
Competitive immunoassay methods
|
|
AU2017297603A1
(en)
|
2016-07-14 |
2019-02-14 |
Fred Hutchinson Cancer Research Center |
Multiple bi-specific binding domain constructs with different epitope binding to treat cancer
|
|
HUE054228T2
(hu)
|
2016-07-15 |
2021-08-30 |
Acceleron Pharma Inc |
Használható actriia polipeptideket tartalmazó összetételek a pulmonalis hypertónia kezelésében történõ alkalmazásra
|
|
CN110461315B
(zh)
|
2016-07-15 |
2025-05-02 |
诺华股份有限公司 |
使用与激酶抑制剂组合的嵌合抗原受体治疗和预防细胞因子释放综合征
|
|
WO2018014260A1
(en)
|
2016-07-20 |
2018-01-25 |
Nanjing Legend Biotech Co., Ltd. |
Multispecific antigen binding proteins and methods of use thereof
|
|
KR20230117482A
(ko)
|
2016-07-27 |
2023-08-08 |
오비아이 파머 인코퍼레이티드 |
면역원성/치료 글리칸 조성물 및 그의 용도
|
|
PL3490582T3
(pl)
|
2016-07-27 |
2024-09-23 |
Acceleron Pharma Inc. |
Kompozycje do zastosowania w leczeniu mielofibrozy
|
|
IL316970A
(en)
|
2016-07-28 |
2025-01-01 |
Novartis Ag |
Combination therapies of chimeric antigen receptors and PD-1 inhibitors
|
|
CN110062767B
(zh)
|
2016-07-29 |
2023-07-11 |
台湾浩鼎生技股份有限公司 |
人抗体、药物组合物和方法
|
|
CN109415444B
(zh)
|
2016-07-29 |
2024-03-01 |
中外制药株式会社 |
显示增加的备选fviii辅因子功能活性的双特异性抗体
|
|
KR20190036551A
(ko)
|
2016-08-01 |
2019-04-04 |
노파르티스 아게 |
Pro-m2 대식세포 분자의 억제제를 병용하는, 키메라 항원 수용체를 이용한 암의 치료
|
|
CN109689099B
(zh)
|
2016-08-05 |
2023-02-28 |
中外制药株式会社 |
用于预防或治疗il-8相关疾病的组合物
|
|
JP2019530434A
(ja)
|
2016-08-05 |
2019-10-24 |
ジェネンテック, インコーポレイテッド |
アゴニスト活性を有する多価及び多重エピトープ抗体ならびに使用方法
|
|
JP7250674B2
(ja)
|
2016-08-08 |
2023-04-03 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
がんの治療及び診断方法
|
|
CN109689111B
(zh)
|
2016-08-11 |
2024-04-05 |
基因泰克公司 |
吡咯并苯并二氮杂䓬前药及其抗体缀合物
|
|
ES3034020T3
(en)
|
2016-08-15 |
2025-08-12 |
Hoffmann La Roche |
Chromatography method for quantifying a non-ionic surfactant in a composition comprising the non-ionic surfactant and a polypeptide
|
|
US10538592B2
(en)
|
2016-08-22 |
2020-01-21 |
Cho Pharma, Inc. |
Antibodies, binding fragments, and methods of use
|
|
EP4529966A3
(en)
|
2016-08-29 |
2025-06-18 |
Fred Hutchinson Cancer Center |
Chelating platform for delivery of radionuclides
|
|
RU2756982C2
(ru)
|
2016-08-31 |
2021-10-07 |
Онкотерапи Сайенс, Инк. |
Моноклональное антитело против melk и его использование
|
|
JP7018210B2
(ja)
|
2016-09-06 |
2022-02-10 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
ヒドロキシピリドネートアクチニド/ランタニド体外除去剤の製剤
|
|
EP3510046A4
(en)
|
2016-09-07 |
2020-05-06 |
The Regents of the University of California |
ANTIBODIES AGAINST OXIDATION-SPECIFIC EPITOPES
|
|
SG10201607778XA
(en)
|
2016-09-16 |
2018-04-27 |
Chugai Pharmaceutical Co Ltd |
Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
|
|
CN116731197A
(zh)
|
2016-09-19 |
2023-09-12 |
豪夫迈·罗氏有限公司 |
基于补体因子的亲和层析
|
|
AU2017329024A1
(en)
|
2016-09-19 |
2019-03-21 |
Celgene Corporation |
Methods of treating immune disorders using pd-1 binding proteins
|
|
US10766958B2
(en)
|
2016-09-19 |
2020-09-08 |
Celgene Corporation |
Methods of treating vitiligo using PD-1 binding antibodies
|
|
JOP20190009A1
(ar)
|
2016-09-21 |
2019-01-27 |
Alx Oncology Inc |
أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
|
|
HRP20231015T1
(hr)
|
2016-09-23 |
2023-12-08 |
F. Hoffmann-La Roche Ag |
Upotreba antagonista il-13 u liječenju atopičnog dermatitisa
|
|
EP3519034A4
(en)
|
2016-09-29 |
2021-02-17 |
The Regents of The University of California |
CHELATING MOLECULES
|
|
WO2018097871A2
(en)
|
2016-09-29 |
2018-05-31 |
The Regents Of The University Of California |
Separation of metal ions by liquid-liquid extraction
|
|
ES2897217T3
(es)
|
2016-09-30 |
2022-02-28 |
Hoffmann La Roche |
Anticuerpos biespecíficos frente a p95HER2
|
|
EP3522934A4
(en)
|
2016-10-05 |
2020-04-15 |
Acceleron Pharma Inc. |
COMPOSITIONS AND METHODS FOR TREATING KIDNEY DISEASES
|
|
EP3522933B1
(en)
|
2016-10-05 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Methods for preparing antibody drug conjugates
|
|
MX2019003934A
(es)
|
2016-10-06 |
2019-07-10 |
Genentech Inc |
Métodos terapéuticos y de diagnóstico para el cáncer.
|
|
TWI762516B
(zh)
|
2016-10-06 |
2022-05-01 |
日商腫瘤療法 科學股份有限公司 |
針對fzd10之單株抗體及其用途
|
|
WO2018067992A1
(en)
|
2016-10-07 |
2018-04-12 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
|
WO2018068201A1
(en)
|
2016-10-11 |
2018-04-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against ctla-4
|
|
US11828683B2
(en)
|
2016-10-19 |
2023-11-28 |
Alexion Pharmaceuticals, Inc. |
Method of quantitating unbound C5a in a sample
|
|
ES2848206T3
(es)
|
2016-10-19 |
2021-08-05 |
Alexion Pharma Inc |
Un método de cuantificar C5 sin unir en una muestra
|
|
EP3411071A4
(en)
|
2016-10-20 |
2019-08-28 |
I-Mab |
NOVEL MONOCLONAL CD47 ANTIBODY AND USES THEREOF
|
|
CN110366558A
(zh)
|
2016-10-28 |
2019-10-22 |
班扬生物标记公司 |
针对泛素c末端水解酶l1(uch-l1)和胶质纤维酸性蛋白(gfap)的抗体及相关方法
|
|
JP2019535250A
(ja)
|
2016-10-29 |
2019-12-12 |
ジェネンテック, インコーポレイテッド |
抗mic抗体及び使用方法
|
|
CN109923128A
(zh)
|
2016-11-15 |
2019-06-21 |
基因泰克公司 |
用于用抗cd20/抗cd3双特异性抗体进行治疗的给药
|
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
|
JOP20190100A1
(ar)
|
2016-11-19 |
2019-05-01 |
Potenza Therapeutics Inc |
بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها
|
|
TWI822055B
(zh)
|
2016-11-21 |
2023-11-11 |
台灣浩鼎生技股份有限公司 |
共軛生物分子、醫藥組成物及方法
|
|
CN110248959B
(zh)
|
2016-12-07 |
2023-06-30 |
基因泰克公司 |
抗tau抗体和使用方法
|
|
EP3551220B1
(en)
|
2016-12-07 |
2025-01-29 |
Genentech, Inc. |
Anti-tau antibodies and methods of use
|
|
JP7141407B2
(ja)
|
2016-12-13 |
2022-09-22 |
エフ.ホフマン-ラ ロシュ アーゲー |
腫瘍試料における標的抗原の存在を決定する方法
|
|
US10132797B2
(en)
|
2016-12-19 |
2018-11-20 |
Tolero Pharmaceuticals, Inc. |
Profiling peptides and methods for sensitivity profiling
|
|
CN110087682B
(zh)
|
2016-12-19 |
2023-12-15 |
豪夫迈·罗氏有限公司 |
用靶向性4-1bb(cd137)激动剂的组合疗法
|
|
JP7247091B2
(ja)
|
2016-12-20 |
2023-03-28 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
抗cd20/抗cd3二重特異性抗体と4-1bb(cd137)アゴニストの併用療法
|
|
JOP20190134A1
(ar)
|
2016-12-23 |
2019-06-02 |
Potenza Therapeutics Inc |
بروتينات رابطة لمولد ضد مضادة لنيوروبيلين وطرق استخدامها
|
|
EP3565843A1
(en)
|
2017-01-03 |
2019-11-13 |
H. Hoffnabb-La Roche Ag |
Bispecific antigen binding molecules comprising anti-4-1bb clone 20h4.9
|
|
TW201825515A
(zh)
|
2017-01-04 |
2018-07-16 |
美商伊繆諾金公司 |
Met抗體以及其免疫結合物及用途
|
|
KR102646046B1
(ko)
|
2017-01-06 |
2024-03-08 |
바이오션, 인코포레이티드 |
Erbb2 항체 및 이의 용도
|
|
US11535662B2
(en)
|
2017-01-26 |
2022-12-27 |
Novartis Ag |
CD28 compositions and methods for chimeric antigen receptor therapy
|
|
US11266745B2
(en)
|
2017-02-08 |
2022-03-08 |
Imaginab, Inc. |
Extension sequences for diabodies
|
|
TWI778018B
(zh)
|
2017-02-10 |
2022-09-21 |
美商建南德克公司 |
抗類胰蛋白酶抗體、其組合物及其用途
|
|
WO2018152496A1
(en)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions and methods for the diagnosis and treatment of zika virus infection
|
|
EP3589647A1
(en)
|
2017-02-28 |
2020-01-08 |
Novartis AG |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
|
ES2953595T3
(es)
|
2017-03-01 |
2023-11-14 |
Hoffmann La Roche |
Procedimientos diagnósticos y terapéuticos para el cáncer
|
|
JP7116736B2
(ja)
|
2017-03-02 |
2022-08-10 |
ノバルティス アーゲー |
操作されたヘテロ二量体タンパク質
|
|
AR111249A1
(es)
|
2017-03-22 |
2019-06-19 |
Genentech Inc |
Composiciones de anticuerpo optimizadas para el tratamiento de trastornos oculares
|
|
JP7216006B2
(ja)
|
2017-03-22 |
2023-01-31 |
ジェネンテック, インコーポレイテッド |
ヒドロゲル架橋ヒアルロン酸プロドラッグ組成物及び方法
|
|
TWI808963B
(zh)
|
2017-03-22 |
2023-07-21 |
法商賽諾菲公司 |
使用人類化抗cxcr5抗體治療狼瘡
|
|
EP3600408A1
(en)
|
2017-03-27 |
2020-02-05 |
H. Hoffnabb-La Roche Ag |
Improved antigen binding receptor formats
|
|
PE20200152A1
(es)
|
2017-03-27 |
2020-01-17 |
Hoffmann La Roche |
Receptores de union a antigeno mejorados
|
|
KR20190133162A
(ko)
|
2017-03-28 |
2019-12-02 |
제넨테크, 인크. |
신경퇴행성 질병의 치료 방법
|
|
WO2018178074A1
(en)
|
2017-03-29 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Trimeric antigen binding molecules specific for a costimulatory tnf receptor
|
|
JP7205995B2
(ja)
|
2017-03-29 |
2023-01-17 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
共刺激性tnf受容体に対する二重特異性抗原結合分子
|
|
JP7196094B2
(ja)
|
2017-03-29 |
2022-12-26 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
共刺激tnf受容体のための二重特異性抗原結合分子
|
|
JOP20190203A1
(ar)
|
2017-03-30 |
2019-09-03 |
Potenza Therapeutics Inc |
بروتينات رابطة لمولد ضد مضادة لـ tigit وطرق استخدامها
|
|
CN110382525B
(zh)
|
2017-04-03 |
2023-10-20 |
豪夫迈·罗氏有限公司 |
免疫缀合物
|
|
AU2018247767B2
(en)
|
2017-04-03 |
2025-01-30 |
F. Hoffmann-La Roche Ag |
Antibodies binding to STEAP-1
|
|
JP7426825B2
(ja)
|
2017-04-03 |
2024-02-02 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
抗pd-1抗体と突然変異il-2とまたはil-15とのイムノコンジュゲート
|
|
EP3606956B1
(en)
|
2017-04-04 |
2024-07-31 |
F. Hoffmann-La Roche AG |
Novel bispecific antigen binding molecules capable of specific binding to cd40 and to fap
|
|
US11285207B2
(en)
|
2017-04-05 |
2022-03-29 |
Hoffmann-La Roche Inc. |
Bispecific antibodies specifically binding to PD1 and LAG3
|
|
TWI707871B
(zh)
|
2017-04-05 |
2020-10-21 |
瑞士商赫孚孟拉羅股份公司 |
抗lag3抗體
|
|
RU2665790C1
(ru)
|
2017-04-17 |
2018-09-04 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело к pd-l1
|
|
US12460208B2
(en)
|
2017-04-18 |
2025-11-04 |
Parr Biotechnology Co., Ltd. |
Immunomodulatory polynucleotides and uses thereof
|
|
CN108728444A
(zh)
|
2017-04-18 |
2018-11-02 |
长春华普生物技术股份有限公司 |
免疫调节性多核苷酸及其应用
|
|
JP7248588B2
(ja)
|
2017-04-21 |
2023-03-29 |
ジェネンテック, インコーポレイテッド |
疾患の治療のためのklk5アンタゴニストの使用
|
|
EP3615569A1
(en)
|
2017-04-25 |
2020-03-04 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis and treatment of epstein barr virus infection
|
|
EP3615068A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
US20200055948A1
(en)
|
2017-04-28 |
2020-02-20 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
EA201992626A1
(ru)
|
2017-05-05 |
2020-04-24 |
Аллакос Инк. |
Способы и композиции для лечения аллергических заболеваний глаз
|
|
WO2018213097A1
(en)
|
2017-05-15 |
2018-11-22 |
University Of Rochester |
Broadly neutralizing anti-influenza monoclonal antibody and uses thereof
|
|
US11359014B2
(en)
|
2017-05-16 |
2022-06-14 |
Alector Llc |
Anti-siglec-5 antibodies and methods of use thereof
|
|
WO2018215535A1
(en)
|
2017-05-23 |
2018-11-29 |
Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Novel cd73 antibody, preparation and uses thereof
|
|
EP3409322A1
(en)
|
2017-06-01 |
2018-12-05 |
F. Hoffmann-La Roche AG |
Treatment method
|
|
MY204117A
(en)
|
2017-06-22 |
2024-08-08 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
WO2019000223A1
(en)
|
2017-06-27 |
2019-01-03 |
Nanjing Legend Biotech Co., Ltd. |
ENABLERS OF IMMUNE EFFECTOR CELLS OF CHIMERIC ANTIBODIES AND METHODS OF USE THEREOF
|
|
MX2019015738A
(es)
|
2017-06-27 |
2020-02-20 |
Novartis Ag |
Regimen de dosificacion para anticuerpos anti-tim-3 y usos de los mismos.
|
|
MX2019015293A
(es)
|
2017-06-30 |
2020-02-17 |
Zymeworks Inc |
Fab quimericos estabilizados.
|
|
SG11201913137VA
(en)
|
2017-07-11 |
2020-01-30 |
Compass Therapeutics Llc |
Agonist antibodies that bind human cd137 and uses thereof
|
|
EP3655430A1
(en)
|
2017-07-19 |
2020-05-27 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Antibodies and methods for the diagnosis and treatment of hepatitis b virus infection
|
|
AU2018302283B2
(en)
|
2017-07-20 |
2025-07-10 |
Novartis Ag |
Dosage regimens of anti-LAG-3 antibodies and uses thereof
|
|
IL271888B2
(en)
|
2017-07-21 |
2024-09-01 |
Genentech Inc |
Therapeutic and diagnostic methods for cancer
|
|
CN111448210B
(zh)
|
2017-07-26 |
2024-05-14 |
四十七公司 |
抗SIRP-α抗体及相关方法
|
|
JP7407699B2
(ja)
|
2017-07-28 |
2024-01-04 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性抗体製剤
|
|
RS64419B1
(sr)
|
2017-08-03 |
2023-09-29 |
Alector Llc |
Anti-trem2 antitela i postupci za njihovu upotrebu
|
|
CN110662765B
(zh)
|
2017-08-03 |
2023-09-29 |
艾利妥 |
抗cd33抗体及其使用方法
|
|
CN111295394B
(zh)
|
2017-08-11 |
2024-06-11 |
豪夫迈·罗氏有限公司 |
抗cd8抗体及其用途
|
|
JP7196160B2
(ja)
|
2017-09-12 |
2022-12-26 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
Mcl-1阻害剤アルボシジブを用いた、bcl-2阻害剤に対して非感受性である癌の治療レジメン
|
|
US20200216542A1
(en)
|
2017-09-20 |
2020-07-09 |
Chugai Seiyaku Kabushiki Kaisha |
Dosage regimen for combination therapy using pd-1 axis binding antagonists and gpc3 targeting agent
|
|
CA3071236A1
(en)
|
2017-09-29 |
2019-04-04 |
Chugai Seiyaku Kabushiki Kaisha |
Multispecific antigen-binding molecule having blood coagulation factor viii (fviii) cofactor function-substituting activity, and pharmaceutical formulation containing said molecule as active ingredient
|
|
EA039662B1
(ru)
|
2017-10-03 |
2022-02-24 |
Закрытое Акционерное Общество "Биокад" |
Антитела, специфичные к cd47 и pd-l1
|
|
RU2698048C2
(ru)
|
2017-10-03 |
2019-08-21 |
Закрытое Акционерное Общество "Биокад" |
МОНОКЛОНАЛЬНОЕ АНТИТЕЛО К IL-5Rα
|
|
US20200237766A1
(en)
|
2017-10-13 |
2020-07-30 |
Tolero Pharmaceuticals, Inc. |
Pkm2 activators in combination with reactive oxygen species for treatment of cancer
|
|
EP3697441B1
(en)
|
2017-10-20 |
2023-06-07 |
F. Hoffmann-La Roche AG |
Method for generating multispecific antibodies from monospecific antibodies
|
|
CA3078676A1
(en)
|
2017-10-30 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
Method for in vivo generation of multispecific antibodies from monospecific antibodies
|
|
WO2019089753A2
(en)
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
|
WO2019086394A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
The compbody - a multivalent target binder
|
|
BR112020006443A2
(pt)
|
2017-11-01 |
2020-09-29 |
F. Hoffmann-La Roche Ag |
anticorpos biespecíficos, ácido nucleico isolado, vetor ou célula hospedeira, método para produzir um anticorpo biespecífico e para tratar um indivíduo, composição farmacêutica e uso do anticorpo
|
|
CA3079036A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
Combination therapy with targeted ox40 agonists
|
|
CN111246884A
(zh)
|
2017-11-01 |
2020-06-05 |
豪夫迈·罗氏有限公司 |
新颖的含有tnf家族配体三聚体的抗原结合分子
|
|
EP3704146B1
(en)
|
2017-11-01 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Trifab-contorsbody
|
|
CA3077664A1
(en)
|
2017-11-06 |
2019-05-09 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
EP4640703A2
(en)
|
2017-11-14 |
2025-10-29 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-c1s antibodies and methods of use
|
|
CA3081602A1
(en)
|
2017-11-16 |
2019-05-23 |
Novartis Ag |
Combination therapies
|
|
EP3713961A2
(en)
|
2017-11-20 |
2020-09-30 |
Compass Therapeutics LLC |
Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
EP3723799A1
(en)
|
2017-12-14 |
2020-10-21 |
H. Hoffnabb-La Roche Ag |
Use of a cea cd3 bispecific antibody and a pd-1 axis binding antagonist in a dosage regime to treat cancer
|
|
EP3502140A1
(en)
|
2017-12-21 |
2019-06-26 |
F. Hoffmann-La Roche AG |
Combination therapy of tumor targeted icos agonists with t-cell bispecific molecules
|
|
JP7394058B2
(ja)
|
2017-12-21 |
2023-12-07 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
新規抗原結合部分の特異性試験のためのユニバーサルレポーター細胞アッセイ
|
|
JP2021508246A
(ja)
|
2017-12-21 |
2021-03-04 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
新規抗原結合部分の特異性試験のためのcar−t細胞アッセイ
|
|
WO2019122052A2
(en)
|
2017-12-21 |
2019-06-27 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a2/wt1
|
|
WO2019126472A1
(en)
|
2017-12-22 |
2019-06-27 |
Genentech, Inc. |
Use of pilra binding agents for treatment of a disease
|
|
JP7383617B2
(ja)
|
2017-12-28 |
2023-11-20 |
ナンジン レジェンド バイオテック カンパニー,リミテッド |
Pd-l1に対する抗体及びそのバリアント
|
|
JP7369127B2
(ja)
|
2017-12-28 |
2023-10-25 |
ナンジン レジェンド バイオテック カンパニー,リミテッド |
Tigitに対する単一ドメイン抗体及びその変異体
|
|
EP3731865A1
(en)
|
2017-12-29 |
2020-11-04 |
F. Hoffmann-La Roche AG |
Method for improving vegf-receptor blocking selectivity of an anti-vegf antibody
|
|
CN111886246B
(zh)
|
2017-12-29 |
2024-12-17 |
艾莱克特有限责任公司 |
抗tmem106b抗体及其使用方法
|
|
KR20200118029A
(ko)
|
2018-01-04 |
2020-10-14 |
아이코닉 테라퓨틱스, 인코포레이티드 |
항-조직 인자 항체, 항체-약물 결합체, 및 관련 방법
|
|
WO2019139987A1
(en)
|
2018-01-09 |
2019-07-18 |
Elstar Therapeutics, Inc. |
Calreticulin binding constructs and engineered t cells for the treatment of diseases
|
|
KR20250114571A
(ko)
|
2018-01-15 |
2025-07-29 |
난징 레전드 바이오테크 씨오., 엘티디. |
Pd-1에 대한 단일-도메인 항체 및 이의 변이체
|
|
WO2019143636A1
(en)
|
2018-01-16 |
2019-07-25 |
Lakepharma, Inc. |
Bispecific antibody that binds cd3 and another target
|
|
EP3746116A1
(en)
|
2018-01-31 |
2020-12-09 |
Novartis AG |
Combination therapy using a chimeric antigen receptor
|
|
WO2019149716A1
(en)
|
2018-01-31 |
2019-08-08 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies comprising an antigen-binding site binding to lag3
|
|
US11472874B2
(en)
|
2018-01-31 |
2022-10-18 |
Alector Llc |
Anti-MS4A4A antibodies and methods of use thereof
|
|
WO2019149715A1
(en)
|
2018-01-31 |
2019-08-08 |
F. Hoffmann-La Roche Ag |
Stabilized immunoglobulin domains
|
|
CN118772288A
(zh)
|
2018-02-08 |
2024-10-15 |
豪夫迈·罗氏有限公司 |
双特异性抗原结合分子和使用方法
|
|
JP7654402B2
(ja)
|
2018-02-09 |
2025-04-01 |
アクセルロン ファーマ インコーポレイテッド |
異所性骨化を処置するための方法
|
|
WO2019157358A1
(en)
|
2018-02-09 |
2019-08-15 |
Genentech, Inc. |
Therapeutic and diagnostic methods for mast cell-mediated inflammatory diseases
|
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
|
CA3092108A1
(en)
|
2018-02-26 |
2019-08-29 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
JP2021514648A
(ja)
|
2018-03-01 |
2021-06-17 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
新規の標的抗原結合部分のための特異性アッセイ
|
|
MX2020009468A
(es)
|
2018-03-13 |
2020-10-22 |
Hoffmann La Roche |
Terapias de combinacion de agonistas de 4-1bb con anticuerpos anti-cd20.
|
|
TWI841551B
(zh)
|
2018-03-13 |
2024-05-11 |
瑞士商赫孚孟拉羅股份公司 |
使用靶向4-1bb (cd137)之促效劑的組合療法
|
|
US20200040103A1
(en)
|
2018-03-14 |
2020-02-06 |
Genentech, Inc. |
Anti-klk5 antibodies and methods of use
|
|
US12152073B2
(en)
|
2018-03-14 |
2024-11-26 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
TW202003562A
(zh)
|
2018-03-14 |
2020-01-16 |
中國大陸商北京軒義醫藥科技有限公司 |
抗密連蛋白18.2(cldn18.2)抗體
|
|
TWI887899B
(zh)
|
2018-03-15 |
2025-06-21 |
日商中外製藥股份有限公司 |
對茲卡病毒具有交叉反應性的抗登革病毒抗體之用途
|
|
WO2019179420A1
(en)
|
2018-03-20 |
2019-09-26 |
Wuxi Biologics (Shanghai) Co., Ltd. |
Novel anti-tim-3 antibodies
|
|
MA52091A
(fr)
|
2018-03-21 |
2021-01-27 |
Alx Oncology Inc |
Anticorps contre la protéine régulatrice de signal alpha et procédés d'utilisation
|
|
JP2021519073A
(ja)
|
2018-03-29 |
2021-08-10 |
ジェネンテック, インコーポレイテッド |
哺乳動物細胞におけるラクトジェニック活性の制御
|
|
JP7104458B2
(ja)
|
2018-04-02 |
2022-07-21 |
上海博威生物医薬有限公司 |
リンパ球活性化遺伝子-3(lag-3)結合抗体およびその使用
|
|
JP7394067B2
(ja)
|
2018-04-04 |
2023-12-07 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
がん患者における腫瘍抗原を検出するための診断アッセイ
|
|
EP3775883A1
(en)
|
2018-04-04 |
2021-02-17 |
F. Hoffmann-La Roche AG |
Diagnostic assays to detect tumor antigens in cancer patients
|
|
TW202011029A
(zh)
|
2018-04-04 |
2020-03-16 |
美商建南德克公司 |
偵測及定量fgf21之方法
|
|
EP3774883A1
(en)
|
2018-04-05 |
2021-02-17 |
Gilead Sciences, Inc. |
Antibodies and fragments thereof that bind hepatitis b virus protein x
|
|
BR112020016997A2
(pt)
|
2018-04-13 |
2021-01-19 |
F. Hoffmann-La Roche Ag |
Moléculas de ligação e de ácido nucleico isolada, vetor, célula hospedeira, métodos para produzir a molécula de ligação, para tratar um indivíduo com câncer e para regular positivamente ou prolongar a atividade de células t, composição farmacêutica e uso da molécula de ligação
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
AR114789A1
(es)
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
US12084489B2
(en)
|
2018-05-02 |
2024-09-10 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis, prevention, and treatment of Epstein Barr virus infection
|
|
WO2019213384A1
(en)
|
2018-05-03 |
2019-11-07 |
University Of Rochester |
Anti-influenza neuraminidase monoclonal antibodies and uses thereof
|
|
SG11202011308VA
(en)
|
2018-05-14 |
2020-12-30 |
Werewolf Therapeutics Inc |
Activatable cytokine polypeptides and methods of use thereof
|
|
JP7460609B2
(ja)
|
2018-05-14 |
2024-04-02 |
ウェアウルフ セラピューティクス, インコーポレイテッド |
活性化可能なインターロイキン-2ポリペプチド及びその使用方法
|
|
MX2020012378A
(es)
|
2018-05-18 |
2021-02-09 |
Hoffmann La Roche |
Administracion intracelular dirigida de acidos nucleicos grandes.
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
JP2021525243A
(ja)
|
2018-05-21 |
2021-09-24 |
コンパス セラピューティクス リミテッド ライアビリティ カンパニー |
Nk細胞による標的細胞の殺傷を増進するための組成物および方法
|
|
CR20200566A
(es)
|
2018-05-25 |
2021-02-19 |
Alector Llc |
Anticuerpos anti-sirpa y metodos de utilización de los mismos
|
|
US20210213063A1
(en)
|
2018-05-25 |
2021-07-15 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
EP3805400A4
(en)
|
2018-06-04 |
2022-06-29 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule showing changed half-life in cytoplasm
|
|
JP7382970B2
(ja)
|
2018-06-08 |
2023-11-17 |
アレクトル エルエルシー |
抗Siglec-7抗体及びその使用方法
|
|
TWI890660B
(zh)
|
2018-06-13 |
2025-07-21 |
瑞士商諾華公司 |
Bcma 嵌合抗原受體及其用途
|
|
KR20210022004A
(ko)
|
2018-06-18 |
2021-03-02 |
안위타 바이오사이언시스, 인코포레이티드 |
항-메소텔린 작제물 및 이의 용도
|
|
MX2020013798A
(es)
|
2018-06-19 |
2021-08-11 |
Atarga Llc |
Moléculas de anticuerpo de componente de complemento 5 y sus usos.
|
|
AU2019288728A1
(en)
|
2018-06-23 |
2021-01-14 |
Genentech, Inc. |
Methods of treating lung cancer with a pd-1 axis binding antagonist, a platinum agent, and a topoisomerase ii inhibitor
|
|
WO2020006176A1
(en)
|
2018-06-27 |
2020-01-02 |
Obi Pharma, Inc. |
Glycosynthase variants for glycoprotein engineering and methods of use
|
|
US20210355199A1
(en)
|
2018-06-28 |
2021-11-18 |
University Of Virginia Patent Foundation |
Compositions and methods for detecting and regulating fibronectin-integrin interaction and signaling
|
|
CA3099176A1
(en)
|
2018-06-29 |
2020-01-02 |
Alector Llc |
Anti-sirp-beta1 antibodies and methods of use thereof
|
|
CN112955465A
(zh)
|
2018-07-03 |
2021-06-11 |
马伦戈治疗公司 |
抗tcr抗体分子及其用途
|
|
CN112424228B
(zh)
|
2018-07-04 |
2024-08-09 |
豪夫迈·罗氏有限公司 |
新型双特异性激动性4-1bb抗原结合分子
|
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
PE20210186A1
(es)
|
2018-07-13 |
2021-02-02 |
Alector Llc |
Anticuerpos anti-sortilina y metodos para su uso
|
|
TW202011991A
(zh)
|
2018-07-18 |
2020-04-01 |
美商建南德克公司 |
用pd-1軸結合拮抗劑、抗代謝劑及鉑劑治療肺癌之方法
|
|
MX2021000745A
(es)
|
2018-07-20 |
2021-03-26 |
Surface Oncology Inc |
Composiciones anti-cd112r y metodos.
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
AU2019310590A1
(en)
|
2018-07-26 |
2021-01-14 |
Sumitomo Pharma Oncology, Inc. |
Methods for treating diseases associated with abnormal acvr1 expression and acvr1 inhibitors for use in the same
|
|
EA202190183A1
(ru)
|
2018-07-27 |
2021-05-18 |
Алектор Ллс |
Антитела к siglec-5 и способы их применения
|
|
CN113286824A
(zh)
|
2018-08-03 |
2021-08-20 |
中外制药株式会社 |
包含两个彼此连接的抗原结合结构域的抗原结合分子
|
|
JP7542521B2
(ja)
|
2018-08-08 |
2024-08-30 |
ジェネンテック, インコーポレイテッド |
タンパク質製剤のためのトリプトファン誘導体及びl-メチオニンの使用
|
|
MX2021001431A
(es)
|
2018-08-10 |
2021-05-12 |
Chugai Pharmaceutical Co Ltd |
Molecula de union al antigeno anti grupo de diferenciacion 137 (cd137) y su uso.
|
|
TW202021618A
(zh)
|
2018-08-17 |
2020-06-16 |
美商23與我有限公司 |
抗il1rap抗體及其使用方法
|
|
WO2020041360A1
(en)
|
2018-08-21 |
2020-02-27 |
Quidel Corporation |
Dbpa antibodies and uses thereof
|
|
EP3841123A2
(en)
|
2018-08-23 |
2021-06-30 |
Seagen Inc. |
Anti-tigit antibodies
|
|
AU2019331018A1
(en)
|
2018-08-31 |
2021-03-11 |
Alector Llc |
Anti-cd33 antibodies and methods of use thereof
|
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
|
CN112673022B
(zh)
|
2018-09-10 |
2024-07-09 |
南京传奇生物科技有限公司 |
针对cd33的单结构域抗体及其构建体
|
|
TWI846731B
(zh)
|
2018-09-18 |
2024-07-01 |
瑞士商赫孚孟拉羅股份公司 |
組織蛋白酶(cathepsin)S抑制劑之對抗抗藥抗體形成之用途
|
|
CN112955747A
(zh)
|
2018-09-19 |
2021-06-11 |
豪夫迈·罗氏有限公司 |
膀胱癌的治疗和诊断方法
|
|
ES2955032T3
(es)
|
2018-09-21 |
2023-11-28 |
Hoffmann La Roche |
Métodos de diagnóstico para el cáncer de mama triple negativo
|
|
US20220002370A1
(en)
|
2018-09-27 |
2022-01-06 |
Xilio Development, Inc. |
Masked cytokine polypeptides
|
|
TW202028237A
(zh)
|
2018-09-27 |
2020-08-01 |
美商西建公司 |
SIRPα結合蛋白及其使用方法
|
|
CN112839957A
(zh)
|
2018-09-28 |
2021-05-25 |
协和麒麟株式会社 |
Il-36抗体及其用途
|
|
EP3861026A1
(en)
|
2018-10-01 |
2021-08-11 |
F. Hoffmann-La Roche AG |
Bispecific antigen binding molecules comprising anti-fap clone 212
|
|
EP3861025A1
(en)
|
2018-10-01 |
2021-08-11 |
F. Hoffmann-La Roche AG |
Bispecific antigen binding molecules with trivalent binding to cd40
|
|
TW202028244A
(zh)
|
2018-10-09 |
2020-08-01 |
美商建南德克公司 |
用於確定突觸形成之方法及系統
|
|
AU2019361983A1
(en)
|
2018-10-18 |
2021-05-20 |
Genentech, Inc. |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
|
CN113056287A
(zh)
|
2018-10-24 |
2021-06-29 |
豪夫迈·罗氏有限公司 |
缀合的化学降解诱导剂及使用方法
|
|
RU2724469C2
(ru)
|
2018-10-31 |
2020-06-23 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело, которое специфически связывается с cd20
|
|
WO2020096959A1
(en)
|
2018-11-05 |
2020-05-14 |
Genentech, Inc. |
Methods of producing two chain proteins in prokaryotic host cells
|
|
CN119735694A
(zh)
|
2018-11-13 |
2025-04-01 |
指南针制药有限责任公司 |
对抗检查点分子的多特异性结合构建体及其用途
|
|
EP3884276A2
(en)
|
2018-11-23 |
2021-09-29 |
Katholieke Universiteit Leuven |
Predicting a treatment response in inflammatory bowel disease
|
|
CN113490499A
(zh)
|
2018-12-04 |
2021-10-08 |
大日本住友制药肿瘤公司 |
用作治疗癌症的活性剂的cdk9抑制剂及其多晶型物
|
|
WO2020117257A1
(en)
|
2018-12-06 |
2020-06-11 |
Genentech, Inc. |
Combination therapy of diffuse large b-cell lymphoma comprising an anti-cd79b immunoconjugates, an alkylating agent and an anti-cd20 antibody
|
|
JP2022513198A
(ja)
|
2018-12-10 |
2022-02-07 |
ジェネンテック, インコーポレイテッド |
Fc含有タンパク質への部位特異的コンジュゲーションのための光架橋性ペプチド
|
|
WO2020128927A1
(en)
|
2018-12-20 |
2020-06-25 |
Kyowa Kirin Co., Ltd. |
Fn14 antibodies and uses thereof
|
|
AR117327A1
(es)
|
2018-12-20 |
2021-07-28 |
23Andme Inc |
Anticuerpos anti-cd96 y métodos de uso de estos
|
|
JP2022514280A
(ja)
|
2018-12-20 |
2022-02-10 |
ノバルティス アーゲー |
Mdm2阻害剤のための延長低用量レジメン
|
|
KR20210106437A
(ko)
|
2018-12-20 |
2021-08-30 |
노파르티스 아게 |
3-(1-옥소이소인돌린-2-일)피페리딘-2,6-디온 유도체를 포함하는 투약 요법 및 약학적 조합물
|
|
JP7560459B2
(ja)
|
2018-12-21 |
2024-10-02 |
ジェネンテック, インコーポレイテッド |
アポトーシスに耐性のある細胞株を使用してポリペプチドを生成する方法
|
|
CN113286822A
(zh)
|
2018-12-21 |
2021-08-20 |
豪夫迈·罗氏有限公司 |
靶向肿瘤的超激动性cd28抗原结合分子
|
|
US11608376B2
(en)
|
2018-12-21 |
2023-03-21 |
Hoffmann-La Roche Inc. |
Tumor-targeted agonistic CD28 antigen binding molecules
|
|
SG11202106100VA
(en)
|
2018-12-21 |
2021-07-29 |
23Andme Inc |
Anti-il-36 antibodies and methods of use thereof
|
|
PE20211603A1
(es)
|
2018-12-21 |
2021-08-18 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3
|
|
KR20210142594A
(ko)
|
2018-12-26 |
2021-11-25 |
시티 오브 호프 |
활성화 가능한 차폐된 항-ctla4 결합 단백질
|
|
CN113272327A
(zh)
|
2018-12-30 |
2021-08-17 |
豪夫迈·罗氏有限公司 |
抗兔cd19抗体及其使用方法
|
|
EP3908602A1
(en)
|
2019-01-07 |
2021-11-17 |
Bactolife ApS |
Pathogen binding proteins
|
|
JP2022518399A
(ja)
|
2019-01-14 |
2022-03-15 |
ジェネンテック, インコーポレイテッド |
Pd-1軸結合アンタゴニスト及びrnaワクチンを用いてがんを処置する方法
|
|
WO2020153467A1
(ja)
|
2019-01-24 |
2020-07-30 |
中外製薬株式会社 |
新規がん抗原及びそれらの抗原に対する抗体
|
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
|
CA3127502A1
(en)
|
2019-02-12 |
2020-08-20 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Formulations comprising heterocyclic protein kinase inhibitors
|
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
|
US12479817B2
(en)
|
2019-02-15 |
2025-11-25 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
AU2020222345B2
(en)
|
2019-02-15 |
2022-11-17 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
CN119039441A
(zh)
|
2019-02-21 |
2024-11-29 |
马伦戈治疗公司 |
与nkp30结合的抗体分子及其用途
|
|
CN119661722A
(zh)
|
2019-02-21 |
2025-03-21 |
马伦戈治疗公司 |
结合t细胞相关癌细胞的多功能分子及其用途
|
|
WO2020169698A1
(en)
|
2019-02-21 |
2020-08-27 |
F. Hoffmann-La Roche Ag |
Sensitization of cancer cells to tnf by bet inhibition
|
|
US20220088075A1
(en)
|
2019-02-22 |
2022-03-24 |
The Trustees Of The University Of Pennsylvania |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
JP2022522007A
(ja)
|
2019-02-27 |
2022-04-13 |
アンジーエックス・インコーポレーテッド |
抗tm4sf1抗体を含む抗体薬物コンジュゲートおよびそれを使用する方法
|
|
JP2022521773A
(ja)
|
2019-02-27 |
2022-04-12 |
ジェネンテック, インコーポレイテッド |
抗tigit抗体と抗cd20抗体又は抗cd38抗体とによる処置のための投薬
|
|
EP3935385A1
(en)
|
2019-03-08 |
2022-01-12 |
F. Hoffmann-La Roche AG |
Methods for detecting and quantifying membrane-associated proteins on extracellular vesicles
|
|
CN120189523A
(zh)
|
2019-03-13 |
2025-06-24 |
默克专利股份公司 |
用于脂质化蛋白质结构的制备的方法
|
|
CR20210467A
(es)
|
2019-03-14 |
2021-10-07 |
Genentech Inc |
Tratamiento de cáncer con anticuerpos biespecíficos contra her2xcd3 en combinación con mab anti-her2
|
|
US11793802B2
(en)
|
2019-03-20 |
2023-10-24 |
Sumitomo Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (AML) with venetoclax failure
|
|
JP7547360B2
(ja)
|
2019-03-22 |
2024-09-09 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
Pkm2モジュレーターを含む組成物およびそれを使用する処置の方法
|
|
JP2022527790A
(ja)
|
2019-03-29 |
2022-06-06 |
アターガ,エルエルシー |
抗fgf23抗体分子
|
|
JP2022527565A
(ja)
|
2019-04-12 |
2022-06-02 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
CEA CD3二重特異性抗体及びWntシグナル伝達阻害剤を使用するがんの治療
|
|
WO2020208049A1
(en)
|
2019-04-12 |
2020-10-15 |
F. Hoffmann-La Roche Ag |
Bispecific antigen binding molecules comprising lipocalin muteins
|
|
BR112021020867A2
(pt)
|
2019-04-19 |
2022-01-04 |
Genentech Inc |
Anticorpos, ácido nucleico, vetor, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, usos do anticorpo, método de tratamento de um indivíduo com câncer e método para reduzir a depuração
|
|
AU2020257748A1
(en)
|
2019-04-19 |
2021-11-18 |
Chugai Seiyaku Kabushiki Kaisha |
Chimeric receptor recognizing modification site of antibody
|
|
RU2734432C1
(ru)
|
2019-04-23 |
2020-10-16 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело, которое специфически связывается с GITR
|
|
KR20220004744A
(ko)
|
2019-05-03 |
2022-01-11 |
제넨테크, 인크. |
항-pd-l1 항체를 이용하여 암을 치료하는 방법
|
|
CN119770674A
(zh)
|
2019-05-10 |
2025-04-08 |
武田药品工业株式会社 |
抗体药物缀合物
|
|
EP3968993A1
(en)
|
2019-05-14 |
2022-03-23 |
F. Hoffmann-La Roche AG |
Methods of using anti-cd79b immunoconjugates to treat follicular lymphoma
|
|
EP3969035A4
(en)
|
2019-05-14 |
2023-06-21 |
Werewolf Therapeutics, Inc. |
SEPARATION UNITS AND METHODS AND THEIR USE
|
|
EP3969906A1
(en)
|
2019-05-16 |
2022-03-23 |
ProciseDx Inc. |
Assay detection methods for vcam-1 and calprotectin
|
|
JP2022532385A
(ja)
|
2019-05-16 |
2022-07-14 |
プロサイセデクス インコーポレイティド |
血中のVCAM-1及びα2-マクログロブリンの検出のためのアッセイ方法
|
|
JP2022534227A
(ja)
|
2019-05-23 |
2022-07-28 |
プロサイセデクス インコーポレイティド |
ヒト血清アルブミン、ビタミンd、c反応性タンパク質、及び抗トランスグルタミナーゼ自己抗体の検出のためのアッセイ方法
|
|
AR119264A1
(es)
|
2019-06-05 |
2021-12-09 |
Genentech Inc |
Método para reutilización de cromatografía
|
|
WO2020247159A1
(en)
|
2019-06-06 |
2020-12-10 |
Procisedx Inc. |
DETECTION OF HEMOGLOBIN A1C (HbA1c) IN BLOOD
|
|
CA3140023A1
(en)
|
2019-06-11 |
2020-12-17 |
Alector Llc |
Anti-sortilin antibodies for use in therapy
|
|
WO2020263450A1
(en)
|
2019-06-25 |
2020-12-30 |
Procisedx Inc. |
Detection of anti-tnf alpha drug biologics and anti-drug antibodies
|
|
BR112021026293A2
(pt)
|
2019-06-26 |
2022-03-03 |
Hoffmann La Roche |
Moléculas de ligação, anticorpos humanizados, ácido nucleico isolado, célula hospedeira, métodos para produzir a molécula de ligação ao antígeno, para tratar um indivíduo e suprarregular ou prolongar a atividade de células t citotóxicas, composição farmacêutica e uso da molécula
|
|
JP7354306B2
(ja)
|
2019-06-27 |
2023-10-02 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
新規icos抗体及びそれらを含む腫瘍標的化抗原結合分子
|
|
JP2022538293A
(ja)
|
2019-06-28 |
2022-09-01 |
ジェネンテック, インコーポレイテッド |
液体タンパク質製剤を安定化するための組成物及び方法
|
|
JP2022538139A
(ja)
|
2019-07-02 |
2022-08-31 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
変異体インターロイキン-2及び抗cd8抗体を含む免疫複合体
|
|
EP3998083A4
(en)
|
2019-07-12 |
2023-08-23 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-mutation type fgfr3 antibody and use therefor
|
|
AR119382A1
(es)
|
2019-07-12 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos de pre-direccionamiento y métodos de uso
|
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
|
JP2022540806A
(ja)
|
2019-07-19 |
2022-09-20 |
オンコレスポンス,インク. |
免疫調節抗体およびその使用方法
|
|
PE20220394A1
(es)
|
2019-07-31 |
2022-03-18 |
Hoffmann La Roche |
Anticuerpos que se fijan a gprc5d
|
|
KR20220058540A
(ko)
|
2019-07-31 |
2022-05-09 |
알렉터 엘엘씨 |
항-ms4a4a 항체 및 이의 사용 방법
|
|
JP2022543551A
(ja)
|
2019-07-31 |
2022-10-13 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Gprc5dに結合する抗体
|
|
MX2022002963A
(es)
|
2019-09-12 |
2022-04-06 |
Genentech Inc |
Composiciones y metodos para tratar nefritis lupica.
|
|
AU2020349509A1
(en)
|
2019-09-18 |
2022-03-31 |
Genentech, Inc. |
Anti-KLK7 antibodies, anti-KLK5 antibodies, multispecific anti-KLK5/KLK7 antibodies, and methods of use
|
|
US20220348687A1
(en)
|
2019-09-20 |
2022-11-03 |
Genentech, Inc. |
Dosing for anti-tryptase antibodies
|
|
CR20220127A
(es)
|
2019-09-27 |
2022-05-27 |
Genentech Inc |
Administración de dosis para tratamiento con anticuerpos antagonistas anti-tigit y anti-pd-l1
|
|
US20220281997A1
(en)
|
2019-09-27 |
2022-09-08 |
Nanjing GenScript Biotech Co., Ltd. |
Anti-VHH Domain Antibodies and Use Thereof
|
|
CA3153880A1
(en)
|
2019-10-18 |
2020-06-09 |
Juana Elva HERNANDEZ MONTALVO |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
|
KR20220103947A
(ko)
|
2019-10-21 |
2022-07-25 |
노파르티스 아게 |
베네토클락스 및 tim-3 억제제를 사용한 조합 요법
|
|
CN114786680A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
Tim-3抑制剂及其用途
|
|
US12297451B1
(en)
|
2019-10-25 |
2025-05-13 |
Regeneron Pharmaceuticals, Inc. |
Cell culture medium
|
|
KR20220093323A
(ko)
|
2019-11-05 |
2022-07-05 |
에프. 호프만-라 로슈 아게 |
HLA-A2/WT1 x CD3 이중특이적 항체 및 레날리도미드를 이용한 암의 치료
|
|
US20220389103A1
(en)
|
2019-11-06 |
2022-12-08 |
Genentech, Inc. |
Diagnostic and therapeutic methods for treatment of hematologic cancers
|
|
EP4058593A4
(en)
|
2019-11-12 |
2023-11-15 |
Foundation Medicine, Inc. |
METHOD FOR DETECTING A FUSION GENE CODING A NEOANTIGEN
|
|
MX2022005666A
(es)
|
2019-11-14 |
2022-10-07 |
Werewolf Therapeutics Inc |
Polipeptidos de citocina activables y metodos de uso de los mismos.
|
|
AR120566A1
(es)
|
2019-11-26 |
2022-02-23 |
Novartis Ag |
Receptores de antígeno quiméricos y sus usos
|
|
WO2021113655A1
(en)
|
2019-12-05 |
2021-06-10 |
Alector Llc |
Methods of use of anti-trem2 antibodies
|
|
CA3081503A1
(en)
|
2019-12-06 |
2021-06-06 |
Zymeworks Inc. |
Methods of using a bispecific antigen-binding construct targeting her2 in combination with cdk4/6 inhibitors for the treatment of breast cancer
|
|
AU2020403021A1
(en)
|
2019-12-12 |
2022-06-23 |
Alector Llc |
Methods of use of anti-CD33 antibodies
|
|
CA3160210A1
(en)
|
2019-12-13 |
2021-06-17 |
Alector Llc |
Anti-mertk antibodies and methods of use thereof
|
|
KR20220113790A
(ko)
|
2019-12-13 |
2022-08-16 |
제넨테크, 인크. |
항-ly6g6d 항체 및 사용 방법
|
|
MX2022007635A
(es)
|
2019-12-18 |
2022-07-19 |
Hoffmann La Roche |
Anticuerpos que se unen a hla-a2/mage-a4.
|
|
JP2023506958A
(ja)
|
2019-12-20 |
2023-02-20 |
ノバルティス アーゲー |
骨髄線維症および骨髄異形成症候群を処置するための、デシタビンまたは抗pd-1抗体スパルタリズマブを伴うかまたは伴わない抗tim-3抗体mbg453および抗tgf-ベータ抗体nis793の組合せ
|
|
JP7392145B2
(ja)
|
2019-12-20 |
2023-12-05 |
山東博安生物技術股▲ふん▼有限公司 |
免疫療法のためのt細胞二重特異性抗体の作製における最適化された抗cd3アーム
|
|
EP4081294A2
(en)
|
2019-12-23 |
2022-11-02 |
Genentech, Inc. |
Apolipoprotein l1-specific antibodies and methods of use
|
|
IL294226B2
(en)
|
2019-12-27 |
2025-05-01 |
Chugai Pharmaceutical Co Ltd |
Anti-CTLA-4 antibodies and their use
|
|
GB2609554B
(en)
|
2020-01-03 |
2025-08-20 |
Marengo Therapeutics Inc |
Anti-TCR antibody molecules and uses thereof
|
|
CA3162009A1
(en)
|
2020-01-09 |
2021-07-15 |
F. Hoffmann-La Roche Ag |
New 4-1bbl trimer-containing antigen binding molecules
|
|
CN110818795B
(zh)
|
2020-01-10 |
2020-04-24 |
上海复宏汉霖生物技术股份有限公司 |
抗tigit抗体和使用方法
|
|
IL293752A
(en)
|
2020-01-17 |
2022-08-01 |
Novartis Ag |
Combination comprising a tim-3 inhibitor and a hypomethylating agent for use in treating myelodysplastic syndrome or chronic myelomonocytic leukemia
|
|
CN115298322A
(zh)
|
2020-01-17 |
2022-11-04 |
贝克顿迪金森公司 |
用于单细胞分泌组学的方法和组合物
|
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
WO2022050954A1
(en)
|
2020-09-04 |
2022-03-10 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
WO2021155006A1
(en)
|
2020-01-31 |
2021-08-05 |
Les Laboratoires Servier Sas |
Inhibitors of cyclin-dependent kinases and uses thereof
|
|
CA3165319A1
(en)
|
2020-01-31 |
2021-08-05 |
Vincent K. Tuohy |
Anti-mullerian hormone receptor 2 antibodies and methods of use
|
|
BR112022015077A2
(pt)
|
2020-01-31 |
2022-10-04 |
Genentech Inc |
Métodos para induzir células t cd8+ específicas de neoepítopos em um indivíduo com um tumor e para induzir o tráfico de células t cd8+, vacinas de rna, vacina de rna para uso e antagonistas de ligação
|
|
KR20220140786A
(ko)
|
2020-02-10 |
2022-10-18 |
상하이 에스쿠겐 바이오테크놀로지 컴퍼니 리미티드 |
클라우딘18.2 항체 및 그것의 사용
|
|
CA3167299A1
(en)
|
2020-02-10 |
2021-08-19 |
Shanghai Escugen Biotechnology Co., Ltd. |
Cldn18.2 antibody and use thereof
|
|
TWI895351B
(zh)
|
2020-02-12 |
2025-09-01 |
日商中外製藥股份有限公司 |
用於癌症之治療的抗cd137抗原結合分子
|
|
CA3167851A1
(en)
|
2020-02-24 |
2021-09-02 |
Francesca CIGNARELLA |
Methods of use of anti-trem2 antibodies
|
|
KR20220147109A
(ko)
|
2020-02-27 |
2022-11-02 |
노파르티스 아게 |
키메라 항원 수용체 발현 세포의 제조 방법
|
|
JP7765397B2
(ja)
|
2020-03-12 |
2025-11-06 |
イミューン-オーエヌシー セラピューティクス,インコーポレーテッド |
新規抗lilrb4抗体および派生産物
|
|
EP4118114A1
(en)
|
2020-03-13 |
2023-01-18 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
|
US11919948B2
(en)
|
2020-03-19 |
2024-03-05 |
Genentech, Inc. |
Isoform-selective anti-TGFβ antibodies and methods of use
|
|
US11365239B2
(en)
|
2020-03-20 |
2022-06-21 |
Tsb Therapeutics (Beijing) Co., Ltd. |
Anti-SARS-COV-2 antibodies and uses thereof
|
|
PE20230414A1
(es)
|
2020-03-24 |
2023-03-07 |
Genentech Inc |
Agentes de fijacion a tie2 y metodos de uso
|
|
CA3169908A1
(en)
|
2020-03-26 |
2021-09-30 |
Genentech, Inc. |
Modified mammalian cells having reduced host cell proteins
|
|
EP4126937A1
(en)
|
2020-03-31 |
2023-02-08 |
Alector LLC |
Anti-mertk antibodies and methods of use thereof
|
|
EP4574971A2
(en)
|
2020-03-31 |
2025-06-25 |
Seattle Children's Hospital d/b/a Seattle Children's Research Institute |
Proteomic screening for lysosomal storage diseases
|
|
KR20220161375A
(ko)
|
2020-03-31 |
2022-12-06 |
추가이 세이야쿠 가부시키가이샤 |
다중 특이성 항원 결합 분자를 제조하기 위한 방법
|
|
CA3170570A1
(en)
|
2020-04-01 |
2021-10-07 |
James J. KOBIE |
Monoclonal antibodies against the hemagglutinin (ha) and neuraminidase (na) of influenza h3n2 viruses
|
|
AR121706A1
(es)
|
2020-04-01 |
2022-06-29 |
Hoffmann La Roche |
Moléculas de unión a antígeno biespecíficas dirigidas a ox40 y fap
|
|
WO2021202959A1
(en)
|
2020-04-03 |
2021-10-07 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
EP4126953A2
(en)
|
2020-04-03 |
2023-02-08 |
Alector LLC |
Methods of use of anti-trem2 antibodies
|
|
JP2023521785A
(ja)
|
2020-04-09 |
2023-05-25 |
テクニッシェ ウニベルシタット ミュンヘン |
肺線維症の治療のためのマクロファージへのmiR-21阻害剤の標的送達
|
|
IL297200A
(en)
|
2020-04-15 |
2022-12-01 |
Voyager Therapeutics Inc |
tau binding compounds
|
|
PE20230111A1
(es)
|
2020-04-15 |
2023-01-27 |
Hoffmann La Roche |
Inmunoconjugados
|
|
CR20220531A
(es)
|
2020-04-24 |
2022-11-28 |
Hoffmann La Roche |
Modulacion de enzimas y vías con compuestos de sulfhidrilo y sus derivados
|
|
IL297541A
(en)
|
2020-04-24 |
2022-12-01 |
Genentech Inc |
Methods for using anti-cd79b immunoconjugates
|
|
CA3172880A1
(en)
|
2020-04-27 |
2021-11-04 |
Sotirios Tsimikas |
Isoform-independent antibodies to lipoprotein(a)
|
|
US11634477B2
(en)
|
2020-04-28 |
2023-04-25 |
The Rockefeller University |
Neutralizing anti-SARS-CoV-2 antibodies and methods of use thereof
|
|
EP4143345A1
(en)
|
2020-04-28 |
2023-03-08 |
Genentech, Inc. |
Methods and compositions for non-small cell lung cancer immunotherapy
|
|
WO2021222533A1
(en)
|
2020-04-30 |
2021-11-04 |
Procisedx Inc. |
Methods of detecting antibodies to sars-cov-2
|
|
IL297830A
(en)
|
2020-05-03 |
2023-01-01 |
Levena Suzhou Biopharma Co Ltd |
Antibody-drug conjugates (adcs) comprising an anti-trop-2 antibody, compositions comprising such adcs, as well as methods of making and using the same
|
|
US20230212260A1
(en)
|
2020-05-15 |
2023-07-06 |
Apogenix Ag |
Multi-specific immune modulators
|
|
US11787861B2
(en)
|
2020-05-29 |
2023-10-17 |
23Andme, Inc. |
Anti-CD200R1 antibodies and methods of use thereof
|
|
BR112022024996A2
(pt)
|
2020-06-08 |
2022-12-27 |
Hoffmann La Roche |
Anticorpos, ácido nucleico, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, agente terapêutico, uso do anticorpo e método para tratar um indivíduo com hepatite b
|
|
AU2021289738A1
(en)
|
2020-06-11 |
2022-12-15 |
Genentech, Inc. |
Nanolipoprotein-polypeptide conjugates and compositions, systems, and methods using same
|
|
JP2023529206A
(ja)
|
2020-06-12 |
2023-07-07 |
ジェネンテック, インコーポレイテッド |
がん免疫療法のための方法及び組成物
|
|
CA3181820A1
(en)
|
2020-06-16 |
2021-12-23 |
Genentech, Inc. |
Methods and compositions for treating triple-negative breast cancer
|
|
WO2021257124A1
(en)
|
2020-06-18 |
2021-12-23 |
Genentech, Inc. |
Treatment with anti-tigit antibodies and pd-1 axis binding antagonists
|
|
IL296429A
(en)
|
2020-06-19 |
2022-11-01 |
Hoffmann La Roche |
Protease-activated t-cell bispecific antibodies
|
|
BR112022025856A2
(pt)
|
2020-06-19 |
2023-01-10 |
Hoffmann La Roche |
Anticorpo que se liga a cd3 e cd19, polinucleotídeo isolado, célula hospedeira, método de produção de um anticorpo que se liga a cd3 e cd19, composição farmacêutica, uso do anticorpo, método para tratar uma doença em um indivíduo e invenção
|
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
|
PE20230616A1
(es)
|
2020-06-19 |
2023-04-14 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y folr1
|
|
PE20230835A1
(es)
|
2020-06-19 |
2023-05-19 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3
|
|
JP2023531222A
(ja)
|
2020-06-22 |
2023-07-21 |
アルミラル・ソシエダッド・アノニマ |
抗il-36抗体およびその使用方法
|
|
WO2021260528A1
(en)
|
2020-06-23 |
2021-12-30 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
PE20231361A1
(es)
|
2020-06-23 |
2023-09-05 |
Hoffmann La Roche |
Moleculas agonistas de union al antigeno cd28 que se dirigen a her2
|
|
PH12022500029A1
(en)
|
2020-06-23 |
2024-04-22 |
Kadmon Corp Llc |
Anti-pd-1 antibodies and fusion proteins
|
|
MX2022016453A
(es)
|
2020-06-24 |
2023-02-01 |
Genentech Inc |
Lineas celulares resistentes a la apoptosis.
|
|
EP4172203A1
(en)
|
2020-06-25 |
2023-05-03 |
F. Hoffmann-La Roche AG |
Anti-cd3/anti-cd28 bispecific antigen binding molecules
|
|
WO2022002112A1
(en)
|
2020-07-01 |
2022-01-06 |
Shandong Boan Biotechnology Co., Ltd. |
Anti-gpc3 antibody, anti-gpc3 chimeric antigen receptor and gpc3/cd3 bispecific antibody
|
|
IL298921A
(en)
|
2020-07-10 |
2023-02-01 |
Hoffmann La Roche |
Antibodies which bind to cancer cells and target radionuclides to said cells
|
|
CA3188000A1
(en)
|
2020-07-13 |
2022-01-20 |
Genentech, Inc. |
Cell-based methods for predicting polypeptide immunogenicity
|
|
CR20230009A
(es)
|
2020-07-16 |
2023-01-25 |
Novartis Ag |
Anticuerpos anti-betacelulina, fragmentos de los mismos, y moléculas de unión multiespecíficas
|
|
IL299799A
(en)
|
2020-07-17 |
2023-03-01 |
Genentech Inc |
Anti-NOTCH2 antibodies and methods of use
|
|
PE20231104A1
(es)
|
2020-07-21 |
2023-07-19 |
Genentech Inc |
Inductores quimicos de degradacion conjugados con anticuerpo de brm y metodos de estos
|
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
|
WO2022029573A1
(en)
|
2020-08-03 |
2022-02-10 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
CN115836122A
(zh)
|
2020-08-07 |
2023-03-21 |
基因泰克公司 |
用于预测多肽免疫原性的基于t细胞的方法
|
|
JP2023539201A
(ja)
|
2020-08-28 |
2023-09-13 |
ジェネンテック, インコーポレイテッド |
宿主細胞タンパク質のCRISPR/Cas9マルチプレックスノックアウト
|
|
EP4204020A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
|
WO2022043557A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
EP4211165A1
(en)
|
2020-09-14 |
2023-07-19 |
Ichnos Sciences SA |
Antibodies that bind to il1rap and uses thereof
|
|
MX2023003133A
(es)
|
2020-09-24 |
2023-03-23 |
Hoffmann La Roche |
Prevencion o mitigacion de efectos adversos relacionados con el anticuerpo biespecifico de linfocitos t.
|
|
JP2023544407A
(ja)
|
2020-10-05 |
2023-10-23 |
ジェネンテック, インコーポレイテッド |
抗FcRH5/抗CD3二重特異性抗体による処置のための投与
|
|
JP2023545566A
(ja)
|
2020-10-20 |
2023-10-30 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Pd-1軸結合アンタゴニストとlrrk2阻害剤との併用療法
|
|
AR123855A1
(es)
|
2020-10-20 |
2023-01-18 |
Genentech Inc |
Anticuerpos anti-mertk conjugados con peg y métodos de uso
|
|
EP4232479A1
(en)
|
2020-10-22 |
2023-08-30 |
Janssen Biotech, Inc. |
Proteins comprising delta-like ligand 3 (dll3) antigen binding domains and their uses
|
|
WO2022093981A1
(en)
|
2020-10-28 |
2022-05-05 |
Genentech, Inc. |
Combination therapy comprising ptpn22 inhibitors and pd-l1 binding antagonists
|
|
CN116635419A
(zh)
|
2020-10-30 |
2023-08-22 |
豪夫迈·罗氏有限公司 |
使用CEA CD3双特异性抗体和TGFβ信号传导抑制剂的癌症治疗
|
|
WO2022098638A2
(en)
|
2020-11-04 |
2022-05-12 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
|
MX2023005130A
(es)
|
2020-11-04 |
2023-05-25 |
Genentech Inc |
Dosis subcutanea de anticuerpos biespecificos anti-cd20/anti-cd3.
|
|
WO2022098870A1
(en)
|
2020-11-04 |
2022-05-12 |
The Rockefeller University |
Neutralizing anti-sars-cov-2 antibodies
|
|
US20220153842A1
(en)
|
2020-11-04 |
2022-05-19 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies and anti-cd79b antibody drug conjugates
|
|
EP4240765A2
(en)
|
2020-11-06 |
2023-09-13 |
Novartis AG |
Antibody fc variants
|
|
IL302402A
(en)
|
2020-11-08 |
2023-06-01 |
Seagen Inc |
Combination therapy
|
|
EP4240488A1
(en)
|
2020-11-09 |
2023-09-13 |
Takeda Pharmaceutical Company Limited |
Antibody drug conjugates
|
|
WO2022101120A1
(en)
|
2020-11-10 |
2022-05-19 |
F. Hoffmann-La Roche Ag |
Prevention or mitigation of t-cell engaging agent-related adverse effects
|
|
IL302700A
(en)
|
2020-11-13 |
2023-07-01 |
Novartis Ag |
Combination therapies with chimeric antigen receptor (car)-expressing cells
|
|
JP2023549316A
(ja)
|
2020-11-16 |
2023-11-24 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Fapを標的としたcd40アゴニストとの併用療法
|
|
MX2023005581A
(es)
|
2020-11-16 |
2023-05-29 |
Hoffmann La Roche |
Glucoformas de fab ricas en manosa.
|
|
TW202235431A
(zh)
|
2020-11-25 |
2022-09-16 |
美商艾希利歐發展股份有限公司 |
腫瘤特異性可裂解連接子
|
|
KR20230117169A
(ko)
|
2020-12-02 |
2023-08-07 |
알렉터 엘엘씨 |
항-소르틸린 항체의 사용 방법
|
|
KR20230117122A
(ko)
|
2020-12-04 |
2023-08-07 |
에프. 호프만-라 로슈 아게 |
pH 의존성 돌연변이체 인터류킨-2 폴리펩티드
|
|
WO2022122652A1
(en)
|
2020-12-07 |
2022-06-16 |
UCB Biopharma SRL |
Antibodies against interleukin-22
|
|
PE20231953A1
(es)
|
2020-12-07 |
2023-12-06 |
UCB Biopharma SRL |
Anticuerpos multiespecificos y combinaciones de anticuerpos
|
|
CR20230263A
(es)
|
2020-12-17 |
2023-08-21 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de estos
|
|
WO2022147463A2
(en)
|
2020-12-31 |
2022-07-07 |
Alamar Biosciences, Inc. |
Binder molecules with high affinity and/ or specificity and methods of making and use thereof
|
|
JP2024503826A
(ja)
|
2021-01-06 |
2024-01-29 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Pd1-lag3二重特異性抗体及びcd20 t細胞二重特異性抗体を用いる併用療法
|
|
MX2023008084A
(es)
|
2021-01-12 |
2023-07-13 |
Hoffmann La Roche |
Anticuerpos split que se unen a celulas cancerosas y dirigen radionuclidos a dichas celulas.
|
|
WO2022152701A1
(en)
|
2021-01-13 |
2022-07-21 |
F. Hoffmann-La Roche Ag |
Combination therapy
|
|
US12060411B2
(en)
|
2021-01-15 |
2024-08-13 |
The Rockefeller University |
Neutralizing anti-SARS-CoV-2 antibodies
|
|
BR112023014418A2
(pt)
|
2021-01-20 |
2023-10-31 |
Oncoresponse Inc |
Anticorpos imunomoduladores e usos dos mesmos
|
|
WO2022159984A1
(en)
|
2021-01-22 |
2022-07-28 |
Bionecure Therapeutics, Inc. |
Anti-her-2/trop-2 constructs and uses thereof
|
|
US20240141060A1
(en)
|
2021-01-29 |
2024-05-02 |
Novartis Ag |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
|
EP4301467A1
(en)
|
2021-03-01 |
2024-01-10 |
Xilio Development, Inc. |
Combination of ctla4 and pd1/pdl1 antibodies for treating cancer
|
|
CA3209364A1
(en)
|
2021-03-01 |
2022-09-09 |
Jennifer O'neil |
Combination of masked ctla4 and pd1/pdl1 antibodies for treating cancer
|
|
EP4301418A1
(en)
|
2021-03-03 |
2024-01-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates comprising an anti-bcma antibody
|
|
CN117062839A
(zh)
|
2021-03-12 |
2023-11-14 |
基因泰克公司 |
抗klk7抗体、抗klk5抗体、多特异性抗klk5/klk7抗体和使用方法
|
|
TW202300521A
(zh)
|
2021-03-15 |
2023-01-01 |
美商建南德克公司 |
治療狼瘡性腎炎的組成物及方法
|
|
US20240174746A1
(en)
|
2021-03-18 |
2024-05-30 |
Alector Llc |
Anti-tmem106b antibodies and methods of use thereof
|
|
WO2022197877A1
(en)
|
2021-03-19 |
2022-09-22 |
Genentech, Inc. |
Methods and compositions for time delayed bio-orthogonal release of cytotoxic agents
|
|
US20240166738A1
(en)
|
2021-03-23 |
2024-05-23 |
Alector Llc |
Anti-tmem106b antibodies for treating and preventing coronavirus infections
|
|
GB202104104D0
(en)
|
2021-03-24 |
2021-05-05 |
Liliumx Ltd |
Platform and method
|
|
KR20230162793A
(ko)
|
2021-03-26 |
2023-11-28 |
얀센 바이오테크 인코포레이티드 |
쌍 나선형 필라멘트 타우에 대한 인간화 항체 및 이의 용도
|
|
US20240376171A1
(en)
|
2021-03-30 |
2024-11-14 |
Hoffmann-La Roche Inc. |
Protease-activated polypeptides
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
CA3216170A1
(en)
|
2021-04-09 |
2022-10-13 |
Seagen Inc. |
Methods of treating cancer with anti-tigit antibodies
|
|
AR125344A1
(es)
|
2021-04-15 |
2023-07-05 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-c1s
|
|
TW202305122A
(zh)
|
2021-04-19 |
2023-02-01 |
美商建南德克公司 |
經修飾之哺乳動物細胞
|
|
WO2022223651A1
(en)
|
2021-04-23 |
2022-10-27 |
F. Hoffmann-La Roche Ag |
Prevention or mitigation of nk cell engaging agent-related adverse effects
|
|
EP4330282A1
(en)
|
2021-04-30 |
2024-03-06 |
F. Hoffmann-La Roche AG |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
|
TW202244059A
(zh)
|
2021-04-30 |
2022-11-16 |
瑞士商赫孚孟拉羅股份公司 |
用抗cd20/抗cd3雙特異性抗體進行治療之給藥
|
|
CA3218933A1
(en)
|
2021-05-03 |
2022-11-10 |
UCB Biopharma SRL |
Antibodies
|
|
EP4334343A2
(en)
|
2021-05-06 |
2024-03-13 |
The Rockefeller University |
Neutralizing anti-sars- cov-2 antibodies and methods of use thereof
|
|
CA3218170A1
(en)
|
2021-05-12 |
2022-11-17 |
Jamie Harue HIRATA |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
|
TW202306993A
(zh)
|
2021-05-14 |
2023-02-16 |
美商建南德克公司 |
Trem2之促效劑
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
WO2022243261A1
(en)
|
2021-05-19 |
2022-11-24 |
F. Hoffmann-La Roche Ag |
Agonistic cd40 antigen binding molecules targeting cea
|
|
EP4341385A1
(en)
|
2021-05-21 |
2024-03-27 |
Genentech, Inc. |
Modified cells for the production of a recombinant product of interest
|
|
AR126009A1
(es)
|
2021-06-02 |
2023-08-30 |
Hoffmann La Roche |
Moléculas agonistas de unión al antígeno cd28 que se dirigen a epcam
|
|
TW202306994A
(zh)
|
2021-06-04 |
2023-02-16 |
日商中外製藥股份有限公司 |
抗ddr2抗體及其用途
|
|
CA3216220A1
(en)
|
2021-06-09 |
2022-12-15 |
F. Hoffmann-La Roche Ag |
Combination of a particular braf inhibitor (paradox breaker) and a pd-1 axis binding antagonist for use in the treatment of cancer
|
|
JP2024527262A
(ja)
|
2021-06-16 |
2024-07-24 |
アレクトル エルエルシー |
二重特異性抗MerTK及び抗PDL1抗体ならびにその使用方法
|
|
EP4355783A1
(en)
|
2021-06-16 |
2024-04-24 |
Alector LLC |
Monovalent anti-mertk antibodies and methods of use thereof
|
|
AU2022294106A1
(en)
|
2021-06-18 |
2024-01-25 |
Therini Bio, Inc. |
ANTIBODIES WHICH BIND HUMAN FIBRIN OR FIBRINOGEN γC DOMAIN AND METHODS OF USE
|
|
CA3220353A1
(en)
|
2021-06-25 |
2022-12-29 |
Chugai Seiyaku Kabushiki Kaisha |
Use of anti-ctla-4 antibody
|
|
CR20240026A
(es)
|
2021-06-25 |
2024-03-14 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-ctla-4
|
|
KR20240028452A
(ko)
|
2021-07-02 |
2024-03-05 |
제넨테크, 인크. |
암을 치료하기 위한 방법 및 조성물
|
|
CA3224853A1
(en)
|
2021-07-14 |
2023-01-19 |
Gautham GAMPA |
Anti-c-c motif chemokine receptor 8 (ccr8) antibodies and methods of use
|
|
AU2022315528A1
(en)
|
2021-07-22 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Heterodimeric fc domain antibodies
|
|
JP2024526880A
(ja)
|
2021-07-22 |
2024-07-19 |
ジェネンテック, インコーポレイテッド |
脳標的化組成物及びその使用方法
|
|
MX2024001214A
(es)
|
2021-07-28 |
2024-02-12 |
Hoffmann La Roche |
Metodos y composiciones para tratar cancer.
|
|
CN117794953A
(zh)
|
2021-08-03 |
2024-03-29 |
豪夫迈·罗氏有限公司 |
双特异性抗体及使用方法
|
|
WO2023019239A1
(en)
|
2021-08-13 |
2023-02-16 |
Genentech, Inc. |
Dosing for anti-tryptase antibodies
|
|
WO2023028501A1
(en)
|
2021-08-23 |
2023-03-02 |
Immunitas Therapeutics, Inc. |
Anti-cd161 antibodies and uses thereof
|
|
IL310382A
(en)
|
2021-08-27 |
2024-03-01 |
Genentech Inc |
Methods for treating tau pathologies
|
|
TW202325727A
(zh)
|
2021-08-30 |
2023-07-01 |
美商建南德克公司 |
抗聚泛素多特異性抗體
|
|
WO2023044483A2
(en)
|
2021-09-20 |
2023-03-23 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
JPWO2023053282A1
(OSRAM)
|
2021-09-29 |
2023-04-06 |
|
|
|
TW202321308A
(zh)
|
2021-09-30 |
2023-06-01 |
美商建南德克公司 |
使用抗tigit抗體、抗cd38抗體及pd—1軸結合拮抗劑治療血液癌症的方法
|
|
WO2023056069A1
(en)
|
2021-09-30 |
2023-04-06 |
Angiex, Inc. |
Degrader-antibody conjugates and methods of using same
|
|
KR20240082388A
(ko)
|
2021-10-08 |
2024-06-10 |
추가이 세이야쿠 가부시키가이샤 |
프리필드 시린지 제제의 조제 방법
|
|
WO2023062050A1
(en)
|
2021-10-14 |
2023-04-20 |
F. Hoffmann-La Roche Ag |
New interleukin-7 immunoconjugates
|
|
WO2023062048A1
(en)
|
2021-10-14 |
2023-04-20 |
F. Hoffmann-La Roche Ag |
Alternative pd1-il7v immunoconjugates for the treatment of cancer
|
|
WO2023069919A1
(en)
|
2021-10-19 |
2023-04-27 |
Alector Llc |
Anti-cd300lb antibodies and methods of use thereof
|
|
WO2023073225A1
(en)
|
2021-11-01 |
2023-05-04 |
F. Hoffmann-La Roche Ag |
Treatment of cancer using a hla-a2/wt1 x cd3 bispecific antibody and a 4-1bb (cd137) agonist
|
|
WO2023081898A1
(en)
|
2021-11-08 |
2023-05-11 |
Alector Llc |
Soluble cd33 as a biomarker for anti-cd33 efficacy
|
|
EP4430072A1
(en)
|
2021-11-10 |
2024-09-18 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
|
WO2023088876A1
(en)
|
2021-11-16 |
2023-05-25 |
Apogenix Ag |
Multi-specific immune modulators
|
|
MX2024005680A
(es)
|
2021-11-16 |
2024-05-30 |
Genentech Inc |
Metodos y composiciones para tratar lupus eritematoso sistemico (sle) con mosunetuzumab.
|
|
WO2023088889A1
(en)
|
2021-11-16 |
2023-05-25 |
Apogenix Ag |
CD137 ligands
|
|
US20250034559A1
(en)
|
2021-11-17 |
2025-01-30 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
AU2022402985A1
(en)
|
2021-12-01 |
2024-07-11 |
Kadmon Corporation, Llc |
B7-h4 antibodies and anti-b7-h4 antibody/il-15 fusion proteins
|
|
AR127887A1
(es)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y plap
|
|
CN118541382A
(zh)
|
2021-12-14 |
2024-08-23 |
豪夫迈·罗氏有限公司 |
使用HLA-A2/MAGE-A4 x CD3双特异性抗体和4-1BB(CD137)激动剂治疗癌症
|
|
US20250051472A1
(en)
|
2021-12-17 |
2025-02-13 |
Dana-Farber Cancer Institute, Inc. |
Antibodies and uses thereof
|
|
KR20240116755A
(ko)
|
2021-12-17 |
2024-07-30 |
상하이 헨리우스 바이오테크, 인크. |
항-ox40 항체, 다중 특이적 항체 및 이의 사용 방법
|
|
US20250051755A1
(en)
|
2021-12-17 |
2025-02-13 |
Dana-Farber Cancer Institute, Inc. |
Platform for antibody discovery
|
|
WO2023109901A1
(en)
|
2021-12-17 |
2023-06-22 |
Shanghai Henlius Biotech, Inc. |
Anti-ox40 antibodies and methods of use
|
|
CR20240246A
(es)
|
2021-12-20 |
2024-07-19 |
Hoffmann La Roche |
Anticuerpos agonistas anti-ltbr y anticuerpos biespecificos que los comprenden
|
|
UY40097A
(es)
|
2022-01-07 |
2023-07-14 |
Johnson & Johnson Entpr Innovation Inc |
Materiales y métodos de proteínas de unión a il-1b
|
|
TW202340251A
(zh)
|
2022-01-19 |
2023-10-16 |
美商建南德克公司 |
抗notch2抗體及結合物及其使用方法
|
|
AR128331A1
(es)
|
2022-01-26 |
2024-04-17 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpos y métodos de estos
|
|
AR128330A1
(es)
|
2022-01-26 |
2024-04-17 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpo y métodos de estos
|
|
US20230383010A1
(en)
|
2022-02-07 |
2023-11-30 |
Visterra, Inc. |
Anti-idiotype antibody molecules and uses thereof
|
|
EP4482523A1
(en)
|
2022-02-23 |
2025-01-01 |
Alector LLC |
Methods of use of anti-trem2 antibodies
|
|
WO2023173026A1
(en)
|
2022-03-10 |
2023-09-14 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
US20250136672A1
(en)
|
2022-03-11 |
2025-05-01 |
Janssen Pharmaceutica Nv |
Multispecific antibodies and uses thereof
|
|
IL315544A
(en)
|
2022-03-11 |
2024-11-01 |
Janssen Pharmaceutica Nv |
Multispecific antibodies and their uses
|
|
CA3254098A1
(en)
|
2022-03-11 |
2023-09-14 |
Janssen Pharmaceutica Nv |
MULTISPECIFIC ANTIBODIES AND THEIR USES
|
|
EP4496631A1
(en)
|
2022-03-23 |
2025-01-29 |
F. Hoffmann-La Roche AG |
Combination treatment of an anti-cd20/anti-cd3 bispecific antibody and chemotherapy
|
|
TW202402790A
(zh)
|
2022-03-25 |
2024-01-16 |
英商梅迪繆思有限公司 |
減少呼吸系統感染之方法
|
|
WO2023179740A1
(en)
|
2022-03-25 |
2023-09-28 |
Shanghai Henlius Biotech , Inc. |
Anti-msln antibodies and methods of use
|
|
CN119095880A
(zh)
|
2022-03-28 |
2024-12-06 |
豪夫迈·罗氏有限公司 |
干扰素γ变体以及包含这些变体的抗原结合分子
|
|
WO2023191816A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
MX2024011181A
(es)
|
2022-04-01 |
2024-09-18 |
Genentech Inc |
Derivados de hidroxipropilmetilcelulosa para estabilizar polipeptidos.
|
|
EP4508087A1
(en)
|
2022-04-13 |
2025-02-19 |
Genentech, Inc. |
Pharmaceutical compositions of therapeutic proteins and methods of use
|
|
TW202404637A
(zh)
|
2022-04-13 |
2024-02-01 |
瑞士商赫孚孟拉羅股份公司 |
抗cd20/抗cd3雙特異性抗體之醫藥組成物及使用方法
|
|
IL316174A
(en)
|
2022-04-26 |
2024-12-01 |
Novartis Ag |
Multiple specific antibodies targeting IL-13 and IL-18
|
|
PE20242350A1
(es)
|
2022-05-03 |
2024-12-16 |
Genentech Inc |
Anticuerpos anti-ly6e, inmunoconjugados y usos de estos
|
|
CA3251472A1
(en)
|
2022-05-11 |
2023-11-16 |
Genentech, Inc. |
DOSAGE FOR TREATMENT WITH ANTI-FCRH5/ANTI-CD3 BISPECIFIC ANTIBODIES
|
|
US20250295809A1
(en)
|
2022-05-13 |
2025-09-25 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
TWI866210B
(zh)
|
2022-05-17 |
2024-12-11 |
大陸商蘇州創勝醫藥集團有限公司 |
雙功能蛋白質及其製劑和用途
|
|
US20230416412A1
(en)
|
2022-05-31 |
2023-12-28 |
Hoffmann-La Roche Inc. |
Prevention or mitigation of t-cell engaging agent-related adverse effects
|
|
KR20250022049A
(ko)
|
2022-06-07 |
2025-02-14 |
제넨테크, 인크. |
항-pd-l1 길항제 및 항-tigit 길항제 항체를 포함하는, 폐암 치료의 효율을 결정하는 방법
|
|
WO2023239803A1
(en)
|
2022-06-08 |
2023-12-14 |
Angiex, Inc. |
Anti-tm4sf1 antibody-drug conjugates comprising cleavable linkers and methods of using same
|
|
CN119585308A
(zh)
|
2022-07-13 |
2025-03-07 |
基因泰克公司 |
针对用抗fcrh5/抗cd3双特异性抗体进行的治疗的给药
|
|
KR20250044292A
(ko)
|
2022-07-15 |
2025-03-31 |
피브로겐, 인크. |
변형된 항-갈렉틴-9 항체 및 그의 용도
|
|
EP4558524A1
(en)
|
2022-07-19 |
2025-05-28 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
CR20250056A
(es)
|
2022-07-22 |
2025-03-19 |
Genentech Inc |
Moléculas de unión al antígeno anti-steap1 y sus usos.
|
|
EP4558529A1
(en)
|
2022-07-22 |
2025-05-28 |
Bristol-Myers Squibb Company |
Antibodies binding to human pad4 and uses thereof
|
|
CA3261511A1
(en)
|
2022-07-29 |
2024-02-01 |
Alector Llc |
CD98HC ANTIGEN BINDING DOMAINS AND THEIR USES
|
|
CN119497721A
(zh)
|
2022-07-29 |
2025-02-21 |
艾莱克特有限责任公司 |
转铁蛋白受体抗原结合结构域及其用途
|
|
CN119866348A
(zh)
|
2022-07-29 |
2025-04-22 |
艾莱克特有限责任公司 |
抗gpnmb抗体及其使用方法
|
|
JP2025528068A
(ja)
|
2022-08-03 |
2025-08-26 |
ボイジャー セラピューティクス インコーポレイテッド |
血液脳関門を通過させるための組成物及び方法
|
|
WO2024040216A2
(en)
|
2022-08-19 |
2024-02-22 |
Fibrogen, Inc. |
Anti-ccr8 antibodies and uses thereof
|
|
CN120153254A
(zh)
|
2022-09-01 |
2025-06-13 |
基因泰克公司 |
膀胱癌的治疗和诊断方法
|
|
EP4587123A1
(en)
|
2022-09-15 |
2025-07-23 |
Avidicure IP B.V. |
Multispecific antigen binding proteins for tumor-targeting of nk cells and use thereof
|
|
CN120019071A
(zh)
|
2022-09-15 |
2025-05-16 |
沃雅戈治疗公司 |
Tau结合化合物
|
|
KR20250131767A
(ko)
|
2022-09-28 |
2025-09-03 |
발린크 테라퓨틱스 리미티드 |
다가 단백질 및 스크리닝 방법
|
|
EP4594345A1
(en)
|
2022-09-29 |
2025-08-06 |
F. Hoffmann-La Roche AG |
Protease-activated polypeptides
|
|
KR20250080884A
(ko)
|
2022-10-05 |
2025-06-05 |
알세아 테라퓨틱스, 인크. |
Notch4 항체, 조성물, 및 기도 염증 치료 방법
|
|
EP4598959A1
(en)
|
2022-10-07 |
2025-08-13 |
Genentech, Inc. |
Methods of treating cancer with anti-c-c motif chemokine receptor 8 (ccr8) antibodies
|
|
TW202430211A
(zh)
|
2022-10-10 |
2024-08-01 |
瑞士商赫孚孟拉羅股份公司 |
Gprc5d tcb及imid之組合療法
|
|
TW202423970A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Gprc5d tcb及cd38抗體之組合療法
|
|
TW202423969A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Gprc5d tcb及蛋白酶體抑制劑之組合療法
|
|
US20250250345A1
(en)
|
2022-10-14 |
2025-08-07 |
Ebbil, Ltd. |
Sil-6r and ctgf binding proteins and methods of use thereof
|
|
WO2024086796A1
(en)
|
2022-10-20 |
2024-04-25 |
Alector Llc |
Anti-ms4a4a antibodies with amyloid-beta therapies
|
|
WO2024091991A1
(en)
|
2022-10-25 |
2024-05-02 |
Genentech, Inc. |
Therapeutic and diagnostic methods for multiple myeloma
|
|
WO2024089551A1
(en)
|
2022-10-25 |
2024-05-02 |
Janssen Biotech, Inc. |
Msln and cd3 binding agents and methods of use thereof
|
|
WO2024094741A1
(en)
|
2022-11-03 |
2024-05-10 |
F. Hoffmann-La Roche Ag |
Combination therapy with anti-cd19/anti-cd28 bispecific antibody
|
|
AU2023375342A1
(en)
|
2022-11-08 |
2025-04-24 |
F. Hoffmann-La Roche Ag |
Compositions and methods of treating childhood onset idiopathic nephrotic syndrome
|
|
WO2024100170A1
(en)
|
2022-11-11 |
2024-05-16 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a*02/foxp3
|
|
CN120265651A
(zh)
|
2022-11-25 |
2025-07-04 |
中外制药株式会社 |
用于生产蛋白质的方法
|
|
EP4626418A1
(en)
|
2022-11-29 |
2025-10-08 |
F. Hoffmann-La Roche AG |
Improved cancer immunotherapy
|
|
CN119998314A
(zh)
|
2022-12-08 |
2025-05-13 |
长春百克生物科技股份公司 |
特异性结合rsv的抗体
|
|
EP4634397A1
(en)
|
2022-12-12 |
2025-10-22 |
Genentech Inc. |
Optimizing polypeptide sialic acid content
|
|
AU2023412611A1
(en)
|
2022-12-23 |
2025-07-10 |
Chimagen Biosciences, Ltd |
Novel anti-gprc5d antibody
|
|
EP4646270A2
(en)
|
2023-01-06 |
2025-11-12 |
Alector LLC |
Anti-il18 binding protein antibodies and methods of use thereof
|
|
WO2024149821A1
(en)
|
2023-01-13 |
2024-07-18 |
F. Hoffmann-La Roche Ag |
Treatment of cancer using a hla-a2/wt1 x cd3 bispecific antibody and venetoclax/azacitidine
|
|
AR131638A1
(es)
|
2023-01-18 |
2025-04-16 |
Genentech Inc |
Anticuerpos multiespecíficos y usos de estos
|
|
WO2024156672A1
(en)
|
2023-01-25 |
2024-08-02 |
F. Hoffmann-La Roche Ag |
Antibodies binding to csf1r and cd3
|
|
WO2024163494A1
(en)
|
2023-01-31 |
2024-08-08 |
F. Hoffmann-La Roche Ag |
Methods and compositions for treating non-small cell lung cancer and triple-negative breast cancer
|
|
WO2024163009A1
(en)
|
2023-01-31 |
2024-08-08 |
Genentech, Inc. |
Methods and compositions for treating urothelial bladder cancer
|
|
WO2024168061A2
(en)
|
2023-02-07 |
2024-08-15 |
Ayan Therapeutics Inc. |
Antibody molecules binding to sars-cov-2
|
|
US12257304B2
(en)
|
2023-03-03 |
2025-03-25 |
Arsenal Biosciences, Inc. |
Systems targeting PSMA and CA9
|
|
WO2024191807A1
(en)
|
2023-03-10 |
2024-09-19 |
Seagen Inc. |
Methods of treating cancer with anti-tigit antibodies
|
|
CN120858109A
(zh)
|
2023-03-10 |
2025-10-28 |
基因泰克公司 |
与蛋白酶的融合物及其用途
|
|
WO2024188966A1
(en)
|
2023-03-13 |
2024-09-19 |
F. Hoffmann-La Roche Ag |
Treatment of cancer using an anti-hla-g/anti-cd3 bispecific antibody and a 4‑1bb (cd137) agonist
|
|
WO2024192100A1
(en)
|
2023-03-13 |
2024-09-19 |
Arsenal Biosciences, Inc. |
Synthetic pathway activators
|
|
CN120835901A
(zh)
|
2023-03-13 |
2025-10-24 |
豪夫迈·罗氏有限公司 |
采用pd1-lag3双特异性抗体和hla-g t细胞双特异性抗体的组合疗法
|
|
AU2024248331A1
(en)
|
2023-03-31 |
2025-10-09 |
Genentech, Inc. |
Anti-alpha v beta 8 integrin antibodies and methods of use
|
|
WO2024211236A2
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
WO2024211234A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
WO2024211235A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
AR132404A1
(es)
|
2023-04-12 |
2025-06-25 |
Astrazeneca Uk Ltd |
Compuestos dirigidos a steap2 y uso de los mismos
|
|
WO2024220546A2
(en)
|
2023-04-17 |
2024-10-24 |
Peak Bio, Inc. |
Antibodies and antibody-drug conjugates and methods of use and synthetic processes and intermediates
|
|
AU2024260837A1
(en)
|
2023-04-25 |
2025-10-16 |
Arsenal Biosciences, Inc. |
Novel receptors for transcription regulation
|
|
AU2024270495A1
(en)
|
2023-05-05 |
2025-10-09 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
AR132623A1
(es)
|
2023-05-08 |
2025-07-16 |
Hoffmann La Roche |
PROTEÍNAS DE FUSIÓN DE INTERFERÓN a DIRIGIDAS Y MÉTODOS DE USO
|
|
AU2024268933A1
(en)
|
2023-05-10 |
2025-11-20 |
Chugai Seiyaku Kabushiki Kaisha |
Methods and compositions for treating cancer
|
|
AR132687A1
(es)
|
2023-05-16 |
2025-07-23 |
Hoffmann La Roche |
Inmunoconjugados de il-2 regulados por pd-1 y sus usos
|
|
AU2024270788A1
(en)
|
2023-05-18 |
2024-11-21 |
Clade Therapeutics, Inc. |
Inhibiting natural killer cell cytotoxicity against cell therapies
|
|
TW202448933A
(zh)
|
2023-05-31 |
2024-12-16 |
美商建南德克公司 |
用抗轉化生長因子β3抗體治療TGFβ相關病症之方法
|
|
TW202504918A
(zh)
|
2023-06-01 |
2025-02-01 |
瑞士商赫孚孟拉羅股份公司 |
靶向bcma及cd28的雙特異性抗體
|
|
AR132805A1
(es)
|
2023-06-01 |
2025-07-30 |
Hoffmann La Roche |
Moléculas de unión al antígeno inmunoestimuladoras que se unen específicamente a bcma
|
|
WO2024256843A1
(en)
|
2023-06-16 |
2024-12-19 |
Valink Therapeutics Ltd |
Conjugated molecules
|
|
WO2024261013A1
(en)
|
2023-06-21 |
2024-12-26 |
F. Hoffmann-La Roche Ag |
Combination therapy with fap-targeted lymphotoxin beta receptor agonists
|
|
WO2024263761A1
(en)
|
2023-06-22 |
2024-12-26 |
Genentech, Inc. |
Antibodies and uses thereof
|
|
WO2024263845A1
(en)
|
2023-06-22 |
2024-12-26 |
Genentech, Inc. |
Treatment of multiple myeloma
|
|
WO2024263195A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2024263904A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2025024265A1
(en)
|
2023-07-21 |
2025-01-30 |
Bristol-Myers Squibb Company |
Methods of assessing citrullination and activity of pad4 modulators
|
|
WO2025021838A1
(en)
|
2023-07-26 |
2025-01-30 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3
|
|
WO2025032510A1
(en)
|
2023-08-07 |
2025-02-13 |
Janssen Biotech, Inc. |
Stabilized cd3 antigen binding agents and methods of use thereof
|
|
US20250163182A1
(en)
|
2023-08-07 |
2025-05-22 |
Janssen Biotech, Inc. |
Enpp3 and cd3 binding agents and methods of use thereof
|
|
WO2025034806A1
(en)
|
2023-08-08 |
2025-02-13 |
Wisconsin Alumni Research Foundation |
Single-domain antibodies and variants thereof against fibroblast activation protein
|
|
WO2025032069A1
(en)
|
2023-08-09 |
2025-02-13 |
F. Hoffmann-La Roche Ag |
Mono and multispecific anti-trem2 antibodies, methods and uses thereof
|
|
WO2025032071A1
(en)
|
2023-08-09 |
2025-02-13 |
F. Hoffmann-La Roche Ag |
Mono and multispecific anti-trem2 antibodies, methods and uses thereof
|
|
WO2025042786A1
(en)
|
2023-08-18 |
2025-02-27 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprising circular polyribonucleotides and uses thereof
|
|
WO2025049277A1
(en)
|
2023-08-25 |
2025-03-06 |
Genentech, Inc. |
Methods and compositions for treating non-small cell lung cancer comprising an anti-tigit antagonist antibody and a pd-1 axis binding antagonist
|
|
WO2025056655A1
(en)
|
2023-09-14 |
2025-03-20 |
F. Hoffmann-La Roche Ag |
Antibody formulation
|
|
AR133909A1
(es)
|
2023-09-25 |
2025-11-12 |
Hoffmann La Roche |
ANTICUERPO QUE SE UNE A C3bBb
|
|
WO2025072888A2
(en)
|
2023-09-28 |
2025-04-03 |
Novavax, Inc. |
Anti-sars-cov-2 spike (s) antibodies and their use in treating covid-19
|
|
WO2025085489A1
(en)
|
2023-10-17 |
2025-04-24 |
Bristol-Myers Squibb Company |
Gspt1-degrading compounds, anti-cd33 antibodies and antibody-drug conjugates and uses thereof
|
|
WO2025099120A1
(en)
|
2023-11-09 |
2025-05-15 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies with conditional activity
|
|
WO2025106474A1
(en)
|
2023-11-14 |
2025-05-22 |
Genentech, Inc. |
Therapeutic and diagnostic methods for treating cancer with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
TW202523328A
(zh)
|
2023-11-17 |
2025-06-16 |
美商建南德克公司 |
Mcl-1抑制劑化合物及在抗體藥物結合物中之用途
|
|
WO2025122634A1
(en)
|
2023-12-05 |
2025-06-12 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
WO2025126102A1
(en)
|
2023-12-12 |
2025-06-19 |
Janssen Biotech, Inc. |
Enpp3 × cd3 bispecific antibodies and use thereof
|
|
WO2025129010A1
(en)
|
2023-12-14 |
2025-06-19 |
Genentech, Inc. |
Methods of structure determination using antibodies
|
|
WO2025125386A1
(en)
|
2023-12-14 |
2025-06-19 |
F. Hoffmann-La Roche Ag |
Antibodies that bind to folr1 and methods of use
|
|
WO2025137086A1
(en)
|
2023-12-20 |
2025-06-26 |
Genentech, Inc. |
Reducing alpha-gal
|
|
TW202535935A
(zh)
|
2023-12-20 |
2025-09-16 |
美商艾普吉醫療股份有限公司 |
結合介白素13之抗體之醫藥組合物
|
|
WO2025137523A2
(en)
|
2023-12-20 |
2025-06-26 |
Apogee Therapeutics, Inc. |
Pharmaceutical formulations of antibodies that bind interleukin 13
|
|
WO2025132503A1
(en)
|
2023-12-20 |
2025-06-26 |
F. Hoffmann-La Roche Ag |
Antibodies binding to ceacam5
|
|
WO2025133042A2
(en)
|
2023-12-22 |
2025-06-26 |
F. Hoffmann-La Roche Ag |
Activatable fusion proteins and methods of use
|
|
WO2025149633A1
(en)
|
2024-01-12 |
2025-07-17 |
Laigo Bio B.V. |
Bispecific antigen binding proteins
|
|
WO2025166077A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Compositions comprising progranulin and uses thereof
|
|
WO2025166045A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
β-GLUCOCEREBROSIDASE ENZYMES, FUSION PROTEINS AND COMPLEXES COMPRISING THE SAME, AND METHODS OF USE THEREOF
|
|
WO2025166040A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Multi-specific binding proteins that bind to gpnmb and a blood brain barrier target and methods of use thereof
|
|
WO2025166042A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Cd98hc antigen-binding domains and uses therefor
|
|
WO2025171006A1
(en)
|
2024-02-06 |
2025-08-14 |
Paragon Therapeutics, Inc. |
Il-23 binding protein compositions and methods of use
|
|
WO2025174974A1
(en)
|
2024-02-14 |
2025-08-21 |
Bristol-Myers Squibb Company |
Anti-cd33 antibodies and uses thereof
|
|
WO2025172924A1
(en)
|
2024-02-15 |
2025-08-21 |
Janssen Biotech, Inc. |
Anti-transferrin receptor compositions and methods thereof
|
|
WO2025181189A1
(en)
|
2024-03-01 |
2025-09-04 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3
|
|
WO2025191133A1
(en)
|
2024-03-15 |
2025-09-18 |
Avidicure Ip B.V. |
Il-21 muteins, fusion proteins comprising the same and uses thereof
|
|
WO2025191136A1
(en)
|
2024-03-15 |
2025-09-18 |
Avidicure Ip B.V. |
Muteins of 4-1bb ligand extracellular domain, fusion proteins comprising the same and uses thereof
|
|
WO2025191139A1
(en)
|
2024-03-15 |
2025-09-18 |
Avidicure Ip B.V. |
Conjugates of her2-specific antigen binding proteins and cytokines
|
|
WO2025199338A1
(en)
|
2024-03-20 |
2025-09-25 |
Arsenal Biosciences, Inc. |
Systems targeting slc34a2 and tmprss4 and methods of use thereof
|
|
WO2025199346A1
(en)
|
2024-03-20 |
2025-09-25 |
Arsenal Biosciences, Inc. |
Antigen binding proteins that bind tmprss4 and methods of use thereof
|
|
WO2025215060A1
(en)
|
2024-04-11 |
2025-10-16 |
F. Hoffmann-La Roche Ag |
Antibodies that specifically bind modified oligonucleotides
|
|
WO2025226808A1
(en)
|
2024-04-24 |
2025-10-30 |
Genentech, Inc. |
Compositions and methods of treating lupus nephritis
|
|
WO2025233867A1
(en)
|
2024-05-10 |
2025-11-13 |
Adaptam Therapeutics, S.L. |
Anti-siglec-9 antibodies and uses thereof
|
|
WO2025238135A2
(en)
|
2024-05-17 |
2025-11-20 |
UCB Biopharma SRL |
Antibody with binding specificity for il-11
|
|
WO2025238133A1
(en)
|
2024-05-17 |
2025-11-20 |
UCB Biopharma SRL |
Multispecific antibody with binding specificity for il-11 and il-17
|
|
WO2025250969A1
(en)
|
2024-05-31 |
2025-12-04 |
Vertex Pharmaceuticals Incorporated |
Anti-cd74 antibodies, conjugates and uses thereof
|
|
WO2025255353A1
(en)
|
2024-06-06 |
2025-12-11 |
Apogee Therapeutics, Inc. |
Dosage and administration of an anti-ox40l antibody
|
|
WO2025255349A1
(en)
|
2024-06-06 |
2025-12-11 |
Bristol-Myers Squibb Company |
Multispecific anti-cd40 / anti-fap antibodies and uses thereof
|
|
WO2025255405A1
(en)
|
2024-06-06 |
2025-12-11 |
Bristol-Myers Squibb Company |
Anti-fap antibodies and uses thereof
|
|
WO2025259871A1
(en)
|
2024-06-14 |
2025-12-18 |
Gilead Sciences, Inc. |
Anti-ccr8 antibodies and uses thereof
|