MX2019011423A - Metodos de tratamiento de enfermedades neurodegenerativas. - Google Patents

Metodos de tratamiento de enfermedades neurodegenerativas.

Info

Publication number
MX2019011423A
MX2019011423A MX2019011423A MX2019011423A MX2019011423A MX 2019011423 A MX2019011423 A MX 2019011423A MX 2019011423 A MX2019011423 A MX 2019011423A MX 2019011423 A MX2019011423 A MX 2019011423A MX 2019011423 A MX2019011423 A MX 2019011423A
Authority
MX
Mexico
Prior art keywords
methods
neurodegenerative diseases
treating neurodegenerative
treating
provides methods
Prior art date
Application number
MX2019011423A
Other languages
English (en)
Inventor
Kerchner Geoffrey
Teng Edmond
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2019011423A publication Critical patent/MX2019011423A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención proporciona métodos de tratamiento de tauopatías con anticuerpos anti-Tau.
MX2019011423A 2017-03-28 2018-03-26 Metodos de tratamiento de enfermedades neurodegenerativas. MX2019011423A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762477535P 2017-03-28 2017-03-28
US201762532696P 2017-07-14 2017-07-14
US201762577559P 2017-10-26 2017-10-26
US201762580359P 2017-11-01 2017-11-01
PCT/US2018/024300 WO2018183175A1 (en) 2017-03-28 2018-03-26 Methods of treating neurodegenerative diseases

Publications (1)

Publication Number Publication Date
MX2019011423A true MX2019011423A (es) 2019-11-01

Family

ID=62063590

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019011423A MX2019011423A (es) 2017-03-28 2018-03-26 Metodos de tratamiento de enfermedades neurodegenerativas.

Country Status (13)

Country Link
US (2) US20200131255A1 (es)
EP (1) EP3601337A1 (es)
JP (2) JP2020515543A (es)
KR (1) KR20190133162A (es)
CN (2) CN117205311A (es)
AU (1) AU2018244224A1 (es)
CA (1) CA3055758A1 (es)
IL (1) IL269106A (es)
MA (1) MA48996A (es)
MX (1) MX2019011423A (es)
SG (2) SG10201911225WA (es)
TW (2) TW201836640A (es)
WO (1) WO2018183175A1 (es)

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JP7193457B2 (ja) 2016-12-07 2022-12-20 ジェネンテック， インコーポレイテッド 抗ｔａｕ抗体及び使用方法
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MA47499A (fr) 2017-02-17 2019-12-25 Denali Therapeutics Inc Anticorps anti-tau et leurs procédés d'utilisation
KR20200030029A (ko) 2017-05-02 2020-03-19 프로테나 바이오사이언시즈 리미티드 타우 인식 항체
TW202100550A (zh) 2019-03-03 2021-01-01 愛爾蘭商普羅帝納生物科學公司 識別ｔａｕ之抗體
GB202010652D0 (en) * 2020-07-10 2020-08-26 Wista Lab Ltd Anti-tau antibodies
TW202328177A (zh) * 2021-08-27 2023-07-16 美商建南德克公司 治療ｔａｕ病理學之方法
WO2023150483A1 (en) * 2022-02-03 2023-08-10 Eli Lilly And Company Regional tau imaging for diagnosing and treating alzheimer's disease

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Also Published As

Publication number Publication date
RU2019130976A (ru) 2021-04-28
JP2023055720A (ja) 2023-04-18
KR20190133162A (ko) 2019-12-02
US20200131255A1 (en) 2020-04-30
TW202400231A (zh) 2024-01-01
JP2020515543A (ja) 2020-05-28
CA3055758A1 (en) 2018-10-04
RU2019130976A3 (es) 2021-09-13
AU2018244224A1 (en) 2019-09-19
IL269106A (en) 2019-11-28
TW201836640A (zh) 2018-10-16
CN110494446A (zh) 2019-11-22
US20210284720A1 (en) 2021-09-16
EP3601337A1 (en) 2020-02-05
CN117205311A (zh) 2023-12-12
SG11201908326YA (en) 2019-10-30
SG10201911225WA (en) 2020-01-30
MA48996A (fr) 2020-02-05
WO2018183175A1 (en) 2018-10-04

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