SG11201509371XA - Pathway specific markers for diagnosing irritable bowel syndrome - Google Patents

Pathway specific markers for diagnosing irritable bowel syndrome

Info

Publication number
SG11201509371XA
SG11201509371XA SG11201509371XA SG11201509371XA SG11201509371XA SG 11201509371X A SG11201509371X A SG 11201509371XA SG 11201509371X A SG11201509371X A SG 11201509371XA SG 11201509371X A SG11201509371X A SG 11201509371XA SG 11201509371X A SG11201509371X A SG 11201509371XA
Authority
SG
Singapore
Prior art keywords
bowel syndrome
irritable bowel
specific markers
pathway specific
diagnosing irritable
Prior art date
Application number
SG11201509371XA
Inventor
Stefan Westin
Fabiyola Selvaraj
Fred Princen
Sharat Singh
Original Assignee
Nestec Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestec Sa filed Critical Nestec Sa
Publication of SG11201509371XA publication Critical patent/SG11201509371XA/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9406Neurotransmitters
    • G01N33/942Serotonin, i.e. 5-hydroxy-tryptamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
SG11201509371XA 2013-05-24 2014-05-22 Pathway specific markers for diagnosing irritable bowel syndrome SG11201509371XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361827506P 2013-05-24 2013-05-24
PCT/IB2014/061636 WO2014188378A1 (en) 2013-05-24 2014-05-22 Pathway specific markers for diagnosing irritable bowel syndrome

Publications (1)

Publication Number Publication Date
SG11201509371XA true SG11201509371XA (en) 2015-12-30

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201509371XA SG11201509371XA (en) 2013-05-24 2014-05-22 Pathway specific markers for diagnosing irritable bowel syndrome
SG11201509370UA SG11201509370UA (en) 2013-05-24 2014-05-22 Pathway specific assays for predicting irritable bowel syndrome diagnosis

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201509370UA SG11201509370UA (en) 2013-05-24 2014-05-22 Pathway specific assays for predicting irritable bowel syndrome diagnosis

Country Status (14)

Country Link
US (5) US9891235B2 (en)
EP (2) EP3004068A2 (en)
JP (4) JP2016520199A (en)
KR (2) KR20160010621A (en)
CN (2) CN105392780A (en)
AU (3) AU2014269960B2 (en)
BR (2) BR112015029320A8 (en)
CA (2) CA2912993A1 (en)
HK (2) HK1223361A1 (en)
IL (2) IL242597B (en)
MX (1) MX367046B (en)
RU (2) RU2015155590A (en)
SG (2) SG11201509371XA (en)
WO (2) WO2014188378A1 (en)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105392780A (en) 2013-05-24 2016-03-09 雀巢产品技术援助有限公司 Pathway specific assays for predicting irritable bowel syndrome diagnosis
AU2014284047B2 (en) 2013-06-21 2018-11-22 Ondek Pty Ltd Immunotherapy composition and use thereof
MA39963A (en) * 2014-05-09 2017-03-15 Nogra Pharma Ltd Methods for treating inflammatory bowel disease
ES2748692T3 (en) 2014-11-19 2020-03-17 Nzp Uk Ltd 6.alpha.-alkyl-3,7-dione steroids as intermediates for the production of steroid FXR modulators
AU2015348940A1 (en) 2014-11-19 2017-05-25 Société des Produits Nestlé S.A. Antibodies against serotonin, tryptophan and kynurenine metabolites and uses thereof
DK3221331T3 (en) 2014-11-19 2019-12-02 Nzp Uk Ltd 6-ALKYL-7-HYDROXY-4-EN-3-ON STEROIDS AS INTERMEDIATES FOR THE MANUFACTURE OF STEROID FXR MODULATORS
CN107108687B (en) 2014-11-19 2019-10-29 Nzp英国有限公司 5 β -6- alkyl -7- hydroxyl -3- the ketosteroids as the intermediate for preparing steroids FXR regulator
EP3221334B1 (en) 2014-11-19 2020-02-19 Nzp Uk Limited 6.alpha.-alkyl-6,7-dione steroids as intermediates for the production of steroidal fxr modulators
EP3227685A1 (en) * 2014-12-02 2017-10-11 Nestec S.A. Methods for establishing a vedolizumab dosing regimen to treat patients with irritable bowel disease
CN105987995A (en) * 2015-02-04 2016-10-05 东莞博捷生物科技有限公司 Enzyme linked immunosorbent assay kit for detecting anti-saccharomyces cerevisiae antibody IgG
CN105987996A (en) * 2015-02-09 2016-10-05 东莞博捷生物科技有限公司 Enzyme linked immunosorbent assay kit for detecting human anti-saccharomyces cerevisiae IgA antibody
CN105061305A (en) * 2015-08-31 2015-11-18 河南师范大学 Method for synthesizing 3-methylpyridine-2-carboxylic acid methyl ester in one step
GB201608777D0 (en) 2016-05-18 2016-06-29 Dextra Lab Ltd Compounds
CN106399344B (en) * 2016-06-01 2021-01-01 上海领潮生物新材料有限公司 Preparation method of vin-cdtb fusion protein
WO2018011691A1 (en) * 2016-07-12 2018-01-18 Nestec S.A. Competitive immunoassay methods
CN106188191A (en) * 2016-07-13 2016-12-07 西安电子科技大学 Diagnosis and treatment integration organic molecular probe based on GSH response and preparation method thereof
CN110249048A (en) * 2016-09-15 2019-09-17 太阳基因组学公司 For extracting the universal method of nucleic acid molecules from one of sample or the diverse populations of a plurality of types of microorganisms
US10428370B2 (en) 2016-09-15 2019-10-01 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
US11959125B2 (en) 2016-09-15 2024-04-16 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
US20180164221A1 (en) 2016-12-07 2018-06-14 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
CN110072519A (en) 2016-12-14 2019-07-30 普罗根尼蒂公司 Use JAK inhibitor for treating enterogastric diseases and device
EP3554540B1 (en) 2016-12-14 2023-08-02 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor released using an ingestible device
EP3554362A4 (en) * 2016-12-14 2020-08-12 Warren, Tracy System and methods for developing and using a microbiome-based action component for patient health
WO2018112237A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor
US11134889B2 (en) 2016-12-14 2021-10-05 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a SMAD7 inhibitor
JP2020513280A (en) 2016-12-14 2020-05-14 プロジェニティ, インコーポレイテッド Treatment of digestive tract diseases with immunosuppressants
CA3045310A1 (en) 2016-12-14 2018-06-21 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
CA3046093A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with an il-1 inhibitor
EP3554344A1 (en) 2016-12-14 2019-10-23 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a tlr modulator
WO2018112240A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with a tnf inhibitor
US20200253506A1 (en) 2016-12-14 2020-08-13 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an integrin inhibitor
US11596670B2 (en) 2017-03-30 2023-03-07 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with IL-10 or an IL-10 agonist
US20210138213A1 (en) 2017-03-30 2021-05-13 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
WO2018183941A2 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with live biotherapeutics
WO2018183932A1 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor
CA3054159A1 (en) 2017-03-30 2018-10-04 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a chst15 inhibitor
US20200306516A1 (en) 2017-08-14 2020-10-01 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with glatiramer or a pharmaceutically acceptable salt thereof
EP3750168A1 (en) * 2018-02-09 2020-12-16 Metabolomic Diagnostics Limited A system and method of generating a model to detect, or predict the risk of, an outcome
CN111886501A (en) * 2018-03-19 2020-11-03 富士胶片和光纯药株式会社 Method for judging mental disease
CN112020651A (en) * 2018-04-24 2020-12-01 根特大学 Gut and stool biomarkers for poultry gut health
WO2019232295A1 (en) 2018-06-01 2019-12-05 Progenity, Inc. Devices and systems for gastrointestinal microbiome detection and manipulation
AU2019281024A1 (en) 2018-06-07 2020-12-24 4D Pharma Plc Method for stratifying IBS patients
CN110607335B (en) * 2018-06-14 2021-08-03 中国科学院微生物研究所 Biosynthesis method of nicotinamide adenine dinucleotide compound
CN109324132A (en) * 2018-10-31 2019-02-12 杭州佰辰医学检验所有限公司 Kit and its application of high throughput detection tryptophan and its metabolite
US11488699B1 (en) 2018-12-09 2022-11-01 Cerner Innovation, Inc. Microbiota activity sensor and decision support tool
US11842795B1 (en) * 2018-12-17 2023-12-12 Cerner Innovation, Inc. Irritable bowel syndrome diagnostic sensor and decision support tool
EP3947744A1 (en) * 2019-04-03 2022-02-09 4D Pharma Cork Limited Methods of diagnosing disease
JPWO2020213732A1 (en) * 2019-04-18 2021-04-30 株式会社サイキンソー How to test for irritable bowel syndrome
US11884958B2 (en) * 2019-04-30 2024-01-30 Mayo Foundation For Medical Education And Research Assessing and treating functional gastrointestinal disorders
WO2020232262A1 (en) * 2019-05-16 2020-11-19 Procisedx Inc. Assay detection methods for vcam-1 and calprotectin
CN111351870A (en) * 2019-12-03 2020-06-30 康美华大基因技术有限公司 Irritable bowel syndrome serum metabolism marker combination and diagnostic kit thereof
EP4085256B1 (en) 2020-01-27 2024-01-24 Immundiagnostik AG Test and in vitro diagnosis of irritable bowel syndrome
WO2021152586A1 (en) * 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Methods of analyzing microbiome, immunoglobulin profile and physiological state
EP3913371A1 (en) 2020-05-18 2021-11-24 Neuroimmun GmbH Method and kit for diagnosting irritable bowel syndrome and for its relief through dietary interventions
KR102478205B1 (en) * 2020-09-24 2022-12-15 경희대학교 산학협력단 Method of providing information for diagnosis of upper gastrointestinal tract involvement in patients with crohn’s disease
CN114755313A (en) * 2021-01-08 2022-07-15 复旦大学附属华山医院 Acute kidney injury markers comprising urine NAD + metabolites
CN115724779B (en) * 2021-09-01 2024-03-29 四川大学 Amide alkyl disulfide compound, preparation method and application thereof
WO2023122320A1 (en) * 2021-12-24 2023-06-29 Kuleon Llc Polypodal serotonergic compounds and prodrugs of serotonin receptor agonists and antagonists
WO2023180899A1 (en) * 2022-03-21 2023-09-28 Swain Manish Kumar Device and method for detecting diarrhea
CN116381222A (en) * 2023-03-23 2023-07-04 北京巴瑞医疗器械有限公司 Serotonin luminescent immune detection method and serotonin detection kit
CN116990498A (en) * 2023-09-28 2023-11-03 山东大学齐鲁医院 Application of plasma tryptophan metabolite in diagnosis of migraine in children

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US5571894A (en) 1991-02-05 1996-11-05 Ciba-Geigy Corporation Recombinant antibodies specific for a growth factor receptor
US5587458A (en) 1991-10-07 1996-12-24 Aronex Pharmaceuticals, Inc. Anti-erbB-2 antibodies, combinations thereof, and therapeutic and diagnostic uses thereof
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
AU675929B2 (en) 1992-02-06 1997-02-27 Curis, Inc. Biosynthetic binding protein for cancer marker
ATE149570T1 (en) 1992-08-17 1997-03-15 Genentech Inc BISPECIFIC IMMUNOADHESINS
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
US6218129B1 (en) * 1998-05-15 2001-04-17 Prometheus Laboratories, Inc. Inflammatory bowel disease first step assay system
US6406862B1 (en) 1998-10-06 2002-06-18 The United States Of America As Represented By The Secretary Of The Army Dip-stick assay for C-reactive protein
BR0016467A (en) * 1999-12-15 2002-08-27 Cubist Pharm Inc Lipopeptides as antibacterial agents
US6838250B2 (en) 2000-03-31 2005-01-04 Ortho-Clinical Diagnostics, Inc. Immunoassay for C-reactive protein
DE10121217A1 (en) * 2001-04-30 2002-10-31 Merck Patent Gmbh 6H-Oxazolo [4,5-e] indole derivatives as nicotinic acetylcholine receptor ligands and / or serotonergic ligands
CA2549971A1 (en) 2003-11-03 2005-05-12 Duke University Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction or stroke
US20060154276A1 (en) * 2004-05-13 2006-07-13 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US20060019410A1 (en) 2004-07-21 2006-01-26 Qualyst, Inc. Apparatus, kits and methods for evaluating binding interactions, for detecting and quantifying binding molecules, and for sample preparation
WO2007000046A1 (en) * 2005-06-27 2007-01-04 Holburn Biomedical Corporation Methods for diagnosing functional bowel disease
US7873479B2 (en) 2005-12-01 2011-01-18 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US20100094560A1 (en) 2006-08-15 2010-04-15 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US8278057B2 (en) 2007-09-14 2012-10-02 Nestec S.A. Addressable antibody arrays and methods of use
EP2419529B1 (en) 2009-04-14 2015-05-20 Nestec S.A. Inflammatory bowel disease prognostics
US20120171672A1 (en) 2009-04-14 2012-07-05 Prometheus Laboratories Inc. Inflammatory bowel disease prognostics
EP2778685B1 (en) * 2009-06-25 2017-04-26 Nestec S.A. Methods for diagnosing irritable bowel syndrome
KR20120101038A (en) * 2009-10-30 2012-09-12 프로메테우스 레버러터리스 인코포레이티드 Methods for diagnosing irritable bowel syndrome
BR112012012513A2 (en) * 2009-11-25 2017-01-10 Prometheus Lab Inc method for diagnosing irritable bowel syndrome in a patient, method for monitoring the progression or regression of irritable bowel syndrome in a patient, and for assigning irritable bowel syndrome therapy to a patient in need thereof
US8445215B1 (en) * 2010-07-23 2013-05-21 Nestec S.A. Assays and methods for the detection of Crohn's disease
EP2710383B1 (en) * 2011-05-16 2017-01-11 The University of Newcastle Performance of a biomarker panel for irritable bowel syndrome
EP2769321B1 (en) 2011-10-21 2016-06-01 Nestec S.A. Methods for improving inflammatory bowel disease diagnosis
EP2904395B1 (en) * 2012-10-05 2018-09-05 Nestec S.A. Antibodies to microbiome as diagnostic markers for ibs
CN105392780A (en) 2013-05-24 2016-03-09 雀巢产品技术援助有限公司 Pathway specific assays for predicting irritable bowel syndrome diagnosis
SG11201604495PA (en) * 2013-12-04 2016-07-28 Chugai Pharmaceutical Co Ltd Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules

Also Published As

Publication number Publication date
AU2014269961A1 (en) 2015-11-26
US9891235B2 (en) 2018-02-13
JP2016520199A (en) 2016-07-11
WO2014188377A3 (en) 2015-03-05
BR112015029320A2 (en) 2017-07-25
HK1223361A1 (en) 2017-07-28
RU2015155552A (en) 2017-06-27
SG11201509370UA (en) 2015-12-30
BR112015029318A2 (en) 2017-07-25
JP2019194600A (en) 2019-11-07
KR20160013163A (en) 2016-02-03
JP2016521683A (en) 2016-07-25
IL242597B (en) 2019-02-28
US20180321259A1 (en) 2018-11-08
WO2014188377A2 (en) 2014-11-27
JP2019151637A (en) 2019-09-12
CN105579852A (en) 2016-05-11
CN105579852B (en) 2017-12-01
US20170307637A1 (en) 2017-10-26
HK1223416A1 (en) 2017-07-28
CA2912993A1 (en) 2014-11-27
RU2015155590A (en) 2017-06-29
BR112015029320A8 (en) 2023-01-03
CA2913108A1 (en) 2014-11-27
EP3004892A1 (en) 2016-04-13
AU2018214104A1 (en) 2018-08-30
US10338083B2 (en) 2019-07-02
AU2014269960A1 (en) 2015-11-26
CN105392780A (en) 2016-03-09
US10036759B2 (en) 2018-07-31
IL242595B (en) 2019-01-31
WO2014188378A1 (en) 2014-11-27
EP3004892B1 (en) 2018-10-10
US20160130279A1 (en) 2016-05-12
MX367046B (en) 2019-08-02
US20180136233A1 (en) 2018-05-17
US20160139148A1 (en) 2016-05-19
KR20160010621A (en) 2016-01-27
AU2014269960B2 (en) 2018-05-10
EP3004068A2 (en) 2016-04-13
US9739786B2 (en) 2017-08-22

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