GB1419481A
(en)
|
1973-06-20 |
1975-12-31 |
Ciba Geigy Ag |
Dithiole derivatives useful as additives for lubricating oils and other organic materials
|
EP0876379A1
(en)
|
1996-01-17 |
1998-11-11 |
Novo Nordisk A/S |
Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use
|
DE122010000020I1
(de)
|
1996-04-25 |
2010-07-08 |
Prosidion Ltd |
Verfahren zur Senkung des Blutglukosespiegels in Säugern
|
JP3149958B2
(ja)
|
1996-08-30 |
2001-03-26 |
ノボ ノルディスク アクティーゼルスカブ |
Glp―1誘導体
|
PL192664B1
(pl)
|
1996-12-31 |
2006-11-30 |
Reddys Lab Ltd Dr |
Pochodne azolidynodionu, sposób ich wytwarzania, zawierające je kompozycje farmaceutyczne, ich zastosowanie w leczeniu cukrzycy i związanych z nią chorób oraz związki pośrednie
|
DE19726167B4
(de)
|
1997-06-20 |
2008-01-24 |
Sanofi-Aventis Deutschland Gmbh |
Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
|
WO1999003861A1
(en)
|
1997-07-16 |
1999-01-28 |
Novo Nordisk A/S |
Fused 1,2,4-thiadiazine derivatives, their preparation and use
|
EP2583675A1
(en)
|
1998-02-02 |
2013-04-24 |
Trustees Of Tufts College |
Use of dipeptidylpeptidase inhibitors to regulate glucose metabolism
|
US6903186B1
(en)
|
1998-12-07 |
2005-06-07 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S |
Analogues of GLP-1
|
WO2000064876A1
(en)
|
1999-04-28 |
2000-11-02 |
Aventis Pharma Deutschland Gmbh |
Tri-aryl acid derivatives as ppar receptor ligands
|
WO2000064888A1
(en)
|
1999-04-28 |
2000-11-02 |
Aventis Pharma Deutschland Gmbh |
Di-aryl acid derivatives as ppar receptor ligands
|
HU228466B1
(en)
|
1999-06-23 |
2013-03-28 |
Sanofi Aventis Deutschland |
Substituted benzimidazole
|
EP1076066A1
(en)
|
1999-07-12 |
2001-02-14 |
Zealand Pharmaceuticals A/S |
Peptides for lowering blood glucose levels
|
DE60028791T2
(de)
|
1999-09-10 |
2007-05-24 |
Novo Nordisk A/S |
Modulatoren der protein tyrosin phosphatase (ptpases)
|
WO2001017516A2
(en)
|
1999-09-10 |
2001-03-15 |
Novo Nordisk A/S |
Method of inhibiting protein tyrosine phosphatase 1b and/or t-cell protein tyrosine phosphatase and/or other ptpases with an asp residue at position 48
|
DE19951360A1
(de)
|
1999-10-26 |
2001-05-03 |
Aventis Pharma Gmbh |
Substituierte Indole
|
PE20011010A1
(es)
|
1999-12-02 |
2001-10-18 |
Glaxo Group Ltd |
Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano
|
SE0001899D0
(sv)
|
2000-05-22 |
2000-05-22 |
Pharmacia & Upjohn Ab |
New compounds
|
JP2004518743A
(ja)
|
2000-12-21 |
2004-06-24 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
プロテインキナーゼインヒビターとして有用なピラゾール化合物
|
TWI311133B
(en)
|
2001-04-20 |
2009-06-21 |
Eisai R&D Man Co Ltd |
Carboxylic acid derivativeand the salt thereof
|
GB0113233D0
(en)
|
2001-05-31 |
2001-07-25 |
Glaxo Group Ltd |
Chemical compounds
|
DE50208960D1
(de)
|
2001-08-31 |
2007-01-25 |
Sanofi Aventis Deutschland |
Diarylcycloalkylderivate, verfahren zu ihrer herstellung und ihre verwendung als ppar-aktivatoren
|
JP2005509677A
(ja)
|
2001-11-22 |
2005-04-14 |
ビオヴィトルム・アクチボラゲット |
1型11−ベータ−ヒドロキシステロイドデヒヒドロゲナーゼの阻害剤
|
PL370447A1
(en)
|
2001-11-22 |
2005-05-30 |
Biovitrum Ab |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
|
JP4559078B2
(ja)
|
2001-11-22 |
2010-10-06 |
ビオヴィトルム・アクチボラゲット(プブリクト) |
11−ベータ−ヒドロキシステロイド脱水素酵素タイプ1のインヒビター
|
JP4368683B2
(ja)
|
2002-02-01 |
2009-11-18 |
メルク エンド カムパニー インコーポレーテッド |
糖尿病、肥満症および脂質代謝異常の治療に有用な11−ベータ−ヒドロキシステロイドデヒドロゲナーゼ1阻害剤
|
JP4414232B2
(ja)
|
2002-03-05 |
2010-02-10 |
イーライ リリー アンド カンパニー |
キナーゼ阻害物質
|
HUP0200849A2
(hu)
|
2002-03-06 |
2004-08-30 |
Sanofi-Synthelabo |
N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
|
FR2836915B1
(fr)
|
2002-03-11 |
2008-01-11 |
Aventis Pharma Sa |
Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
|
IL164249A0
(en)
|
2002-04-11 |
2005-12-18 |
Aventis Pharma Gmbh |
Acyl-3-carboxphenylurea derivatives, processes forpreparing them and their use
|
JPWO2003097064A1
(ja)
|
2002-05-17 |
2005-09-15 |
協和醗酵工業株式会社 |
糖尿病治療剤
|
AR040241A1
(es)
|
2002-06-10 |
2005-03-23 |
Merck & Co Inc |
Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia
|
DE10226462A1
(de)
|
2002-06-13 |
2003-12-24 |
Aventis Pharma Gmbh |
Fluorierte Cycloalkyl-derivatisierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament
|
HUP0202001A2
(hu)
|
2002-06-14 |
2005-08-29 |
Sanofi-Aventis |
DDP-IV gátló hatású azabiciklooktán- és nonánszármazékok
|
DE10231370B4
(de)
|
2002-07-11 |
2006-04-06 |
Sanofi-Aventis Deutschland Gmbh |
Thiophenglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
JP2006502247A
(ja)
|
2002-07-12 |
2006-01-19 |
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
複素環で置換されたベンゾイル尿素、その製造方法および医薬としてのその使用
|
BR0312957A
(pt)
|
2002-07-27 |
2005-06-14 |
Astrazeneca Ab |
Composto ou um sal farmaceuticamente aceitável deste, uso do mesmo, composição farmacêutica, e, método para produzir um efeito inibidor de 11betahsd1 em um animal de sangue quente, tal como o homem, em necessidade de tal tratamento
|
EP1537106A1
(en)
|
2002-08-07 |
2005-06-08 |
Mitsubishi Pharma Corporation |
Dihydropyrazolopyridine compounds
|
DE10237723A1
(de)
|
2002-08-17 |
2004-07-08 |
Aventis Pharma Deutschland Gmbh |
Verwendung von IKappaB-Kinase Inhibitoren in der Schmerztherapie
|
DE10237722A1
(de)
|
2002-08-17 |
2004-08-19 |
Aventis Pharma Deutschland Gmbh |
Indol- oder Benzimidazolderivate zur Modulation der IKappaB-Kinase
|
CN1678589A
(zh)
|
2002-09-05 |
2005-10-05 |
安万特医药股份有限公司 |
作为药物的新氨基吲唑衍生物与含有它们的药物组合物
|
ATE345340T1
(de)
|
2002-09-12 |
2006-12-15 |
Hoffmann La Roche |
N-substituierte-1h-indol-5-propansäure verbindungen als ppar-agonisten zur behandlung von diabetis
|
MXPA05003632A
(es)
|
2002-10-11 |
2005-06-03 |
Astrazeneca Ab |
Derivados de piperidina 1, 4-disustituidos y su uso como inhibidores de 11-beta-hidroesteroide deshidrogenasa humana de tipo 1 (11betahsd1).
|
EP1556362B1
(en)
|
2002-10-18 |
2008-03-26 |
Merck & Co., Inc. |
Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
MXPA05004434A
(es)
|
2002-10-24 |
2005-07-26 |
Sterix Ltd |
Inhibidores de 11-beta-hidroxi esteroide deshidrogenasa tipo 1 y tipo 2.
|
WO2004041274A1
(en)
|
2002-11-05 |
2004-05-21 |
Arena Pharmaceuticals, Inc. |
Benzotriazoles and methods of prophylaxis or treatment of metabolic-related disorders thereof
|
AU2003276458A1
(en)
|
2002-11-07 |
2004-06-07 |
Astrazeneca Ab |
2-oxo-ethanesulfonamide derivates
|
FR2847253B1
(fr)
|
2002-11-19 |
2007-05-18 |
Aventis Pharma Sa |
Nouveaux derives de pyridazinones a titre de medicaments et compositions pharmaceutiques les renfermant
|
GB0227813D0
(en)
|
2002-11-29 |
2003-01-08 |
Astrazeneca Ab |
Chemical compounds
|
UY28103A1
(es)
|
2002-12-03 |
2004-06-30 |
Boehringer Ingelheim Pharma |
Nuevas imidazo-piridinonas sustituidas, su preparación y su empleo como medicacmentos
|
DE10258008B4
(de)
|
2002-12-12 |
2006-02-02 |
Sanofi-Aventis Deutschland Gmbh |
Heterocyclische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
DE10258007B4
(de)
|
2002-12-12 |
2006-02-09 |
Sanofi-Aventis Deutschland Gmbh |
Aromatische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
JO2397B1
(en)
|
2002-12-20 |
2007-06-17 |
ميرك شارب اند دوم كوربوريشن |
Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors
|
WO2004056744A1
(en)
|
2002-12-23 |
2004-07-08 |
Janssen Pharmaceutica N.V. |
Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
|
ATE506354T1
(de)
|
2003-01-06 |
2011-05-15 |
Lilly Co Eli |
Substituierte arylcyclopropylacetamide als glucokinaseaktivatoren
|
NO20030115D0
(no)
*
|
2003-01-09 |
2003-01-09 |
Amersham Health As |
Kontrastmiddel
|
CA2512899A1
(en)
|
2003-01-14 |
2004-08-05 |
Arena Pharmaceuticals Inc. |
1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
|
TW200503994A
(en)
|
2003-01-24 |
2005-02-01 |
Novartis Ag |
Organic compounds
|
PL378117A1
(pl)
|
2003-02-11 |
2006-03-06 |
Prosidion Limited |
Tricyklopodstawione związki amidowe
|
US7262196B2
(en)
|
2003-02-11 |
2007-08-28 |
Prosidion Limited |
Tri(cyclo) substituted amide glucokinase activator compounds
|
KR100728425B1
(ko)
|
2003-02-19 |
2007-06-13 |
에프. 호프만-라 로슈 아게 |
Pepck 억제제로서 사용하기 위한 설폰아마이드 치환된크산틴 유도체
|
EP1460075A1
(en)
|
2003-03-21 |
2004-09-22 |
Sanofi-Synthelabo |
Substituted 8-Pyridinyl-6,7,8,9-Tetrahydropyrimido[1,2-a]Pyrimidin-4-one and 8-Phenyl-6-7,8,9-Tetrahydropyrimido[1,2-a]Pyrimidin-4-one derivatives
|
ATE467616T1
(de)
|
2003-04-11 |
2010-05-15 |
High Point Pharmaceuticals Llc |
Verbindungen mit aktivität an der 11beta- hydroxasteroiddehydrogenase
|
DK1615647T3
(da)
|
2003-04-11 |
2010-04-06 |
High Point Pharmaceuticals Llc |
Farmaceutisk anvendelse af kondenserede 1,2,4-triazoler
|
WO2004089367A1
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
Pharmaceutical use of substituted 1,2,4-triazoles
|
CN1784226A
(zh)
|
2003-05-09 |
2006-06-07 |
麦克公司 |
苯并咪唑化合物、含有苯并咪唑化合物的组合物以及使用方法
|
US7067529B2
(en)
|
2003-05-19 |
2006-06-27 |
Hoffmann-La Roche Inc. |
Glutamine fructose-y-phosphate amidotransferase (GFAT) inhibitors
|
EP1631558A1
(en)
|
2003-05-21 |
2006-03-08 |
Biovitrum Ab |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type i
|
US8026264B2
(en)
|
2003-05-29 |
2011-09-27 |
Merck Sharp And Dohme Corp. |
Triazole derivatives as inhibitors of 11-β hydroxysteroid dehydrogenase-1
|
WO2004106343A2
(en)
|
2003-05-30 |
2004-12-09 |
Ufc Limited |
Agelastatin derivatives of antitumour and gsk-3beta-inhibiting alkaloids
|
JP2004359630A
(ja)
|
2003-06-06 |
2004-12-24 |
Yamanouchi Pharmaceut Co Ltd |
ジフルオロジフェニルメタン誘導体及びその塩
|
RS20050915A
(sr)
|
2003-06-13 |
2008-04-04 |
Janssen Pharmaceutica N.V., |
Supstituisani derivati indazolil (indolil)maleimida kao inhibitori kinaze
|
SE0301882D0
(sv)
|
2003-06-25 |
2003-06-25 |
Biovitrum Ab |
New use I
|
SE0301888D0
(sv)
|
2003-06-25 |
2003-06-25 |
Biovitrum Ab |
New use VII
|
WO2004113310A1
(en)
|
2003-06-25 |
2004-12-29 |
Biovitrum Ab |
Use of an inhibitor of 11-b-hydroxysteroid dehydrogenase type 1 compounds for promoting wound healing
|
SE0301886D0
(sv)
|
2003-06-25 |
2003-06-25 |
Biovitrum Ab |
New use V
|
WO2005005477A2
(en)
|
2003-07-11 |
2005-01-20 |
Novo Nordisk A/S |
Stabilised insulin compositions
|
PE20050249A1
(es)
|
2003-07-25 |
2005-06-01 |
Aventis Pharma Gmbh |
Nuevas cianopirrolididas y procedimiento para su preparacion como medicamentos
|
DE10333935A1
(de)
|
2003-07-25 |
2005-02-24 |
Aventis Pharma Deutschland Gmbh |
Neue bicyclische Cyanoheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE10334309A1
(de)
|
2003-07-28 |
2005-03-03 |
Aventis Pharma Deutschland Gmbh |
Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
|
US20050026984A1
(en)
|
2003-07-29 |
2005-02-03 |
Aventis Pharma S.A. |
Substituted thieno [2,3-c] pyrazoles and their use as medicinal products
|
US7008953B2
(en)
|
2003-07-30 |
2006-03-07 |
Agouron Pharmaceuticals, Inc. |
3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
|
AU2004265299B2
(en)
|
2003-08-07 |
2008-05-01 |
Merck & Co., Inc. |
Pyrazole carboxamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
|
MXPA06002941A
(es)
|
2003-09-19 |
2006-05-31 |
Novo Nordisk As |
Derivados de enlace a albumina de peptidos terapeuticos.
|
TW200519105A
(en)
|
2003-10-20 |
2005-06-16 |
Lg Life Science Ltd |
Novel inhibitors of DPP-IV, methods of preparing the same, and pharmaceutical compositions containing the same as an active agent
|
GB0325402D0
(en)
|
2003-10-31 |
2003-12-03 |
Astrazeneca Ab |
Compounds
|
WO2005051373A1
(ja)
|
2003-11-26 |
2005-06-09 |
Takeda Pharmaceutical Company Limited |
受容体機能調節剤
|
DE10359098A1
(de)
|
2003-12-17 |
2005-07-28 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 2-(Piperazin-1-yl)- und 2-([1,4]Diazepan-1-yl)-imidazo[4,5-d]pyridazin-4-one, deren Herstellung und deren Verwendung als Arzneimittel
|
US7301036B2
(en)
|
2003-12-19 |
2007-11-27 |
Merck & Co., Inc. |
Cyclic guanidines, compositions containing such compounds and methods of use
|
EP1557417B1
(en)
|
2003-12-19 |
2007-03-07 |
Sanofi-Aventis |
Substituted 8'-pyri(mi)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-a] pyrimidin-6-one derivatives
|
EP1703908A4
(en)
|
2003-12-22 |
2009-07-08 |
Amgen Inc |
ARYLSULFONAMIDE COMPOUNDS AND RELATED APPLICATIONS
|
CN1898235A
(zh)
|
2003-12-24 |
2007-01-17 |
普罗西迪恩有限公司 |
作为gpcr受体激动剂的杂环衍生物
|
WO2005063729A1
(en)
|
2003-12-25 |
2005-07-14 |
Takeda Pharmaceutical Company Limited |
3-(4-benzyloxyphenyl)propanoic acid derivatives
|
CA2551639A1
(en)
|
2004-01-06 |
2005-07-28 |
Janssen Pharmaceutica N.V. |
(3-oxo-3, 4-dihydro-quinoxalin-2-yl-amino) -benzamide derivatives and related compound as glycogen phosphorylase inhibitors for the treatment of diabetes and obesity
|
RU2006131306A
(ru)
|
2004-01-31 |
2008-03-10 |
Санофи-Авентис Дойчланд Гмбх (De) |
Производные 7-фениламино-4-хинолон-3-карбоновой кислоты, способ их получения и их применение в качестве лекарственных средств
|
DE102004005172A1
(de)
|
2004-02-02 |
2005-08-18 |
Aventis Pharma Deutschland Gmbh |
Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
|
WO2005080360A1
(en)
|
2004-02-18 |
2005-09-01 |
Astrazeneca Ab |
Compounds
|
CN1946666A
(zh)
|
2004-02-27 |
2007-04-11 |
埃姆艮股份有限公司 |
用于治疗代谢性疾病的化合物、药物组合物和方法
|
DE102004010194A1
(de)
|
2004-03-02 |
2005-10-13 |
Aventis Pharma Deutschland Gmbh |
4-Benzimidazol-2-yl-pyridazin-3-on-Derivate, ihre Herstellung und Verwendung in Arzneimitteln
|
ZA200608028B
(en)
|
2004-03-04 |
2009-03-25 |
Kissei Pharmaceutical |
Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof
|
US20050250820A1
(en)
|
2004-03-08 |
2005-11-10 |
Amgen Inc. |
Therapeutic modulation of PPARgamma activity
|
DE102004012068A1
(de)
|
2004-03-12 |
2005-09-29 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue alkyl-haltige 5-Acylindolinone, deren Herstellung und deren Verwendung als Arzneimittel
|
AU2005230864A1
(en)
|
2004-03-29 |
2005-10-20 |
Merck Sharp & Dohme Corp. |
Diaryltriazoles as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
|
EP1732566A4
(en)
|
2004-04-05 |
2010-01-13 |
Takeda Pharmaceutical |
6-azaindole COMPOUND
|
EP1586318A1
(en)
|
2004-04-05 |
2005-10-19 |
Neuropharma S.A.U. |
Thiadiazolidinones as GSK-3 inhibitors
|
EP1734930A2
(en)
|
2004-04-09 |
2006-12-27 |
Smithkline Beecham Corporation |
Low dose pharmaceutical products
|
EP1747215A1
(en)
|
2004-05-12 |
2007-01-31 |
Aventis Pharmaceuticals, Inc. |
Substantially pure 2-{¬2-(2-methylamino-pyrimidin-4-yl)-1h-indole-5-carbonyl|-amino}-3-(phenylpyridin-2-yl-amino)-propionic acid as an ikb kinase inhibitor
|
EP1604988A1
(en)
|
2004-05-18 |
2005-12-14 |
Sanofi-Aventis Deutschland GmbH |
Pyridazinone derivatives, methods for producing them and their use as pharmaceuticals
|
DE102004026532A1
(de)
|
2004-05-29 |
2006-01-05 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
|
DE102004028241B4
(de)
|
2004-06-11 |
2007-09-13 |
Sanofi-Aventis Deutschland Gmbh |
Neue Fluorglykosidderivate von Pyrazolen, diese Verbindungen enthaltende Arzneimittel und Herstellung dieser Arzneimittel
|
WO2006012227A2
(en)
|
2004-06-24 |
2006-02-02 |
Incyte Corporation |
Amido compounds and their use as pharmaceuticals
|
JP2008504274A
(ja)
|
2004-06-24 |
2008-02-14 |
インサイト・コーポレイション |
アミド化合物およびその医薬としての使用
|
DE102004034697A1
(de)
|
2004-07-17 |
2006-02-09 |
Sanofi-Aventis Deutschland Gmbh |
Mit Diphenylamin oder Diphenylaminderivaten substituierte Salicylthiazole, Verfahren zu deren Herstellung und deren Verwendung
|
CA2574875C
(en)
|
2004-07-28 |
2010-09-28 |
Kurt Amrein |
Aryl-pyridine derivatives as 11-beta hsd1 inhibitors
|
DE102004037554A1
(de)
|
2004-08-03 |
2006-03-16 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte 8-Aminoalkylthio-xanthine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
EP1797034B1
(en)
|
2004-08-06 |
2010-06-30 |
Merck Sharp & Dohme Corp. |
Sulfonyl compounds as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
|
DE102004038270A1
(de)
|
2004-08-06 |
2006-03-16 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte, bizyklische 8-Amino-xanthine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE102004038269A1
(de)
|
2004-08-06 |
2006-03-16 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte, bizyklische 8-Piperidino-xanthine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE102004038268A1
(de)
|
2004-08-06 |
2006-03-16 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte, bizyklische 8-Pyrrolidino-xanthine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
WO2006018150A1
(de)
|
2004-08-11 |
2006-02-23 |
Boehringer Ingelheim International Gmbh |
D-xylopyranosyl-phenyl-substituierte cyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
|
MX2007001650A
(es)
|
2004-08-12 |
2007-07-13 |
Prosidion Ltd |
Fenilacetamidas substituidas y su uso como activadores de glucocinasa.
|
DE102004039507A1
(de)
|
2004-08-14 |
2006-03-02 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte 8-Aminoalkoxi-xanthine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
RU2007102288A
(ru)
|
2004-08-18 |
2008-09-27 |
Мебабазис Терапеутикс, Инк. (Us) |
Новые тиазольные ингибиторы фруктозо-1,6-бисфосфатазы
|
JP5208505B2
(ja)
|
2004-08-30 |
2013-06-12 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
11−ベータヒドロキシステロイドデヒドロゲナーゼ阻害剤としてのn−2アダマンタニル−2−フェノキシ−アセトアミド誘導体
|
CN101018790A
(zh)
|
2004-09-11 |
2007-08-15 |
塞诺菲-安万特德国有限公司 |
7-氮杂吲哚以及其用作ppar激动剂的应用
|
WO2006058064A2
(en)
|
2004-11-29 |
2006-06-01 |
Merck & Co., Inc. |
Fused aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
WO2006035796A1
(ja)
|
2004-09-29 |
2006-04-06 |
Kissei Pharmaceutical Co., Ltd. |
1-(β-D-グリコピラノシル)-3-置換含窒素ヘテロ環化合物、それを含有する医薬組成物及びその医薬用途
|
WO2006034804A1
(en)
|
2004-09-29 |
2006-04-06 |
F.Hoffmann-La Roche Ag |
Indozolone derivatives as 11b-hsd1 inhibitors
|
CA2582447C
(en)
|
2004-10-01 |
2012-04-17 |
Merck & Co., Inc. |
Aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
EP2330126B1
(en)
|
2004-10-07 |
2015-12-23 |
Novo Nordisk A/S |
Protracted exendin-4 compounds
|
US7893017B2
(en)
|
2004-10-07 |
2011-02-22 |
Novo Nordisk A/S |
Protracted GLP-1 compounds
|
WO2006040329A1
(en)
|
2004-10-12 |
2006-04-20 |
Novo Nordisk A/S |
1 ibeta- hydroxysteroid dehydrogenase type 1 active spiro compounds
|
KR20070070231A
(ko)
|
2004-10-22 |
2007-07-03 |
스미스클라인 비참 코포레이션 |
Hm74a 수용체 활성을 가지는 크산틴 유도체
|
WO2006045564A1
(en)
|
2004-10-22 |
2006-05-04 |
Smithkline Beecham Corporation |
Xanthine derivatives with hm74a receptor activity
|
EP1807072B1
(en)
|
2004-10-29 |
2009-01-07 |
Eli Lilly And Company |
Cycloalkyl lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
EP1812407A2
(en)
|
2004-11-02 |
2007-08-01 |
Pfizer, Inc. |
Novel compounds of substituted and unsubstituted adamantyl amides
|
EP1666467A1
(en)
|
2004-11-08 |
2006-06-07 |
Evotec AG |
11Beta-HSD1 Inhibitors
|
EP1659113A1
(en)
|
2004-11-08 |
2006-05-24 |
Evotec AG |
Inhibitors of 11beta-hydroxy steroid dehydrogenase type 1 (11beta-HSD1)
|
WO2006051662A1
(ja)
|
2004-11-09 |
2006-05-18 |
Taisho Pharmaceutical Co., Ltd. |
チアゾール誘導体
|
JP2006160733A
(ja)
|
2004-11-15 |
2006-06-22 |
Taisho Pharmaceut Co Ltd |
シアノフルオロピロリジン誘導体を有効成分として含有する医薬
|
WO2007024993A2
(en)
|
2005-08-26 |
2007-03-01 |
Merck & Co., Inc. |
Fused aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
JPWO2006059744A1
(ja)
|
2004-11-30 |
2008-06-05 |
日本ケミファ株式会社 |
ペルオキシソーム増殖剤活性化受容体δの活性化剤
|
JP2008521864A
(ja)
|
2004-12-03 |
2008-06-26 |
トランステック・ファーマ、インコーポレイテッド |
ヘテロ芳香族グルコキナーゼ活性化剤
|
DE102004058449A1
(de)
|
2004-12-03 |
2006-06-14 |
Merck Patent Gmbh |
Tetrahydropyranderivate
|
JP2008007405A
(ja)
|
2004-12-07 |
2008-01-17 |
Takeda Chem Ind Ltd |
カルボキサミド誘導体
|
WO2006065826A2
(en)
|
2004-12-15 |
2006-06-22 |
Merck & Co., Inc. |
Process to chiral beta amino acid derivatives by asymmetric hydrogenation
|
DE102004060542A1
(de)
|
2004-12-16 |
2006-07-06 |
Sanofi-Aventis Deutschland Gmbh |
Hydroxybiphenyl-Carbonsäuren und Derivate, Verfahren zu deren Herstellung und deren Verwendung
|
JP2008524244A
(ja)
|
2004-12-17 |
2008-07-10 |
タケダ サン ディエゴ インコーポレイテッド |
水酸化ステロイド脱水素酵素阻害剤
|
PE20060949A1
(es)
|
2004-12-23 |
2006-10-11 |
Arena Pharm Inc |
Derivados fusionados de pirazol como agonistas del receptor de niacina
|
EP1838706A1
(en)
|
2004-12-24 |
2007-10-03 |
Prosidion Limited |
G-protein coupled receptor agonists
|
JPWO2006068163A1
(ja)
|
2004-12-24 |
2008-06-12 |
大日本住友製薬株式会社 |
二環性ピロール誘導体
|
BRPI0516407A
(pt)
|
2004-12-24 |
2008-09-02 |
Prosidion Ltd |
agonistas de receptor acoplado à proteìna g (gpr116) e uso destes para o tratamento de obesidade e diabetes
|
US7635699B2
(en)
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
EP1846363B1
(en)
|
2005-01-05 |
2012-04-25 |
Abbott Laboratories |
Adamantyl derivatives as inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
DE102005001053A1
(de)
|
2005-01-07 |
2006-07-20 |
Merck Patent Gmbh |
Quadratsäurederivate
|
TW200637839A
(en)
|
2005-01-07 |
2006-11-01 |
Taisho Pharmaceutical Co Ltd |
1-thio-d-glucitol derivatives
|
WO2006073167A1
(ja)
|
2005-01-07 |
2006-07-13 |
Ono Pharmaceutical Co., Ltd. |
ピロリジン誘導体
|
MY148521A
(en)
|
2005-01-10 |
2013-04-30 |
Arena Pharm Inc |
Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
|
DE102005002130A1
(de)
|
2005-01-17 |
2006-07-27 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte N-Aminomethylensulfonamide, ihre Herstellung und Verwendung als Arzneimittel
|
CA2593264C
(en)
|
2005-01-19 |
2012-09-25 |
Merck & Co., Inc. |
Bicyclic pyrimidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
JP2008100916A
(ja)
|
2005-01-24 |
2008-05-01 |
Dainippon Sumitomo Pharma Co Ltd |
インドール類およびそれを含む医薬組成物
|
AR053329A1
(es)
|
2005-01-31 |
2007-05-02 |
Tanabe Seiyaku Co |
Derivados de indol utiles como inhibidores de los transportadores de glucosa dependientes del sodio (sglt)
|
WO2006084176A2
(en)
|
2005-02-03 |
2006-08-10 |
Irm Llc |
Compounds and compositions as ppar modulators
|
US20090156582A1
(en)
|
2005-02-09 |
2009-06-18 |
Tetsuya Tsukamoto |
Pyrazole Compound
|
WO2006086488A2
(en)
|
2005-02-11 |
2006-08-17 |
Eli Lilly And Company |
Substituted thiophene derivatives as glucagon receptor antagonists, preparation and therapeutic uses
|
GB0503056D0
(en)
|
2005-02-14 |
2005-03-23 |
Smithkline Beecham Corp |
Chemical compounds
|
JP2008530074A
(ja)
|
2005-02-14 |
2008-08-07 |
スミスクライン・ビーチャム・コーポレイション |
Hm74a受容体アゴニストとしてのアントラニル酸誘導体
|
GB0503053D0
(en)
|
2005-02-14 |
2005-03-23 |
Smithkline Beecham Corp |
Chemical compounds
|
JP5020065B2
(ja)
|
2005-02-15 |
2012-09-05 |
キッセイ薬品工業株式会社 |
1−置換−7−(β−D−グリコピラノシルオキシ)(アザ)インドール化合物、及びそれを含有する医薬
|
WO2006087309A1
(en)
|
2005-02-15 |
2006-08-24 |
Novo Nordisk A/S |
3,4-dihydro-1h-isoquinoline-2-carboxylic acid 5-aminopyridin-2-yl esters
|
CA2598934A1
(en)
|
2005-02-25 |
2006-08-31 |
Takeda Pharmaceutical Company Limited |
Pyridyl acetic acid compounds
|
DE102005012874A1
(de)
|
2005-03-19 |
2006-09-21 |
Sanofi-Aventis Deutschland Gmbh |
Amid substituierte 8-N-Benzimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE102005012873B4
(de)
|
2005-03-19 |
2007-05-03 |
Sanofi-Aventis Deutschland Gmbh |
Aminocarbonyl substituierte 8-N-Benzimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
WO2006104030A1
(ja)
|
2005-03-25 |
2006-10-05 |
Daiichi Sankyo Company, Limited |
チアゾール化合物
|
TWI357902B
(en)
|
2005-04-01 |
2012-02-11 |
Lg Life Science Ltd |
Dipeptidyl peptidase-iv inhibiting compounds, meth
|
WO2006106423A2
(en)
|
2005-04-07 |
2006-10-12 |
Pfizer Inc. |
Amino sulfonyl derivatives as inhibitors of human 11-.beta.-hydrosysteroid dehydrogenase
|
CA2603757A1
(en)
|
2005-04-13 |
2006-10-26 |
Merck & Co., Inc. |
Niacin receptor agonists, compositions containing such compounds and methods of treatment
|
ATE453656T1
(de)
|
2005-04-15 |
2010-01-15 |
Boehringer Ingelheim Int |
Glucopyranosyl-substituierte (heteroaryloxy- benzyl)-benzen-derivate als sglt-inhibitoren
|
DE102005017605B4
(de)
|
2005-04-16 |
2007-03-15 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte 2-Aminoalkylthio-benzimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE102005018389A1
(de)
|
2005-04-20 |
2006-10-26 |
Sanofi-Aventis Deutschland Gmbh |
Azolderivate als Inhibitoren von Lipasen und Phospholipasen
|
JP5094394B2
(ja)
|
2005-04-20 |
2012-12-12 |
武田薬品工業株式会社 |
縮合複素環化合物
|
EP1883419A4
(en)
|
2005-05-06 |
2010-08-04 |
Bayer Pharmaceuticals Corp |
GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS AND THEIR PHARMACOLOGICAL USES
|
EA012442B1
(ru)
|
2005-05-13 |
2009-10-30 |
Эли Лилли Энд Компани |
Пегилированные соединения glp-1
|
JP4975739B2
(ja)
|
2005-05-17 |
2012-07-11 |
シェーリング コーポレイション |
脂質異常症の処置のための、ニコチン酸受容体アゴニストとしての複素環
|
ATE540950T1
(de)
|
2005-05-25 |
2012-01-15 |
Merck Sharp & Dohme |
Aminocyclohexane als dipeptidylpeptidase-iv- hemmer zur behandlung bzw. prävention von diabetes
|
TW200714597A
(en)
|
2005-05-27 |
2007-04-16 |
Astrazeneca Ab |
Chemical compounds
|
EP1889842A4
(en)
|
2005-06-08 |
2009-07-29 |
Japan Tobacco Inc |
HETEROCYCLIC CONNECTION
|
US7579360B2
(en)
|
2005-06-09 |
2009-08-25 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
WO2006134481A1
(en)
|
2005-06-16 |
2006-12-21 |
Pfizer Inc. |
Inhibitors of 11-beta hydroxysteroid dehydrogenase type 1
|
ES2334518T3
(es)
|
2005-06-16 |
2010-03-11 |
Pfizer, Inc. |
Derivados de n-(piridin-2-il)-sulfonamida.
|
US20080200527A1
(en)
|
2005-06-17 |
2008-08-21 |
Carex Sa |
Cannabinoid Receptor Modulators
|
US7572808B2
(en)
|
2005-06-17 |
2009-08-11 |
Bristol-Myers Squibb Company |
Triazolopyridine cannabinoid receptor 1 antagonists
|
US7605289B2
(en)
|
2005-06-17 |
2009-10-20 |
Amgen, Inc. |
Benzamide derivatives and uses related thereto
|
EP1896445B1
(en)
|
2005-06-22 |
2010-11-10 |
F. Hoffmann-La Roche AG |
( 6-FLU0R0-BENZ0[l, 3] DIOXOLYL) -MORPHOLIN-4-YL-METHANONES AND THEIR USE AS CBl LIGANDS
|
US20060293364A1
(en)
|
2005-06-28 |
2006-12-28 |
Subharekha Raghavan |
Niacin receptor agonists, compositions containing such compounds and methods of treatment
|
WO2007000445A1
(en)
|
2005-06-29 |
2007-01-04 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
AT8564U1
(de)
|
2005-06-29 |
2006-09-15 |
Plansee Se |
Halogenglühlampe mit abblendkappe aus mo-legierung
|
JP5114395B2
(ja)
|
2005-06-30 |
2013-01-09 |
プロシディオン・リミテッド |
Gpcrアゴニスト
|
NZ564758A
(en)
|
2005-06-30 |
2011-03-31 |
Prosidion Ltd |
G-protein coupled receptor agonists
|
WO2007003521A2
(en)
|
2005-07-05 |
2007-01-11 |
F. Hoffmann-La Roche Ag |
Pyridazine derivatives as 11beta-hydroxysteroid dehydrogenase type 1 inhibitors
|
JPWO2007007688A1
(ja)
|
2005-07-08 |
2009-01-29 |
持田製薬株式会社 |
3,5−ジアミノ−1,2,4−トリアゾール誘導体
|
WO2007006760A1
(en)
|
2005-07-08 |
2007-01-18 |
Novo Nordisk A/S |
Dicycloalkyl urea glucokinase activators
|
JP2009500442A
(ja)
|
2005-07-09 |
2009-01-08 |
アストラゼネカ アクチボラグ |
2型糖尿病を処置するためのグルコキナーゼのモジュレーターとしての2−ヘテロシクリルオキシベンゾイルアミノヘテロシクリル化合物
|
US7514439B2
(en)
|
2005-07-11 |
2009-04-07 |
Mitsubishi Tanabe Pharma Corporation |
Oxime derivative and preparations thereof
|
EP1905769B1
(en)
|
2005-07-13 |
2017-03-29 |
Msd K.K. |
Heterocycle-substituted benzimidazole derivative
|
CA2615938C
(en)
|
2005-07-14 |
2014-04-29 |
Novo-Nordisk A/S |
Urea glucokinase activators
|
ES2325558T3
(es)
|
2005-07-20 |
2009-09-08 |
Eli Lilly And Company |
Derivados de piridina como inhibidores de dipeptidilpeptidasa.
|
WO2007009911A1
(en)
|
2005-07-21 |
2007-01-25 |
F. Hoffmann-La Roche Ag |
PYRIDO [2 , 3-D] PYRIMIDINE-2 , 4-DIAMINE COMPOUNDS AS PTPlB INHIBITORS
|
WO2007015744A1
(en)
|
2005-07-21 |
2007-02-08 |
Incyte Corporation |
Disubstituted thienyl compounds and their use as pharmaceuticals
|
UY29694A1
(es)
|
2005-07-28 |
2007-02-28 |
Boehringer Ingelheim Int |
Metodos para prevenir y tratar trastornos metabolicos y nuevos derivados de pirazol-o-glucosido
|
EP1916234B1
(en)
|
2005-07-29 |
2014-11-12 |
Takeda Pharmaceutical Company Limited |
Cyclopropanecarboxylic acid compound
|
FR2889190A1
(fr)
|
2005-08-01 |
2007-02-02 |
Merck Sante Soc Par Actions Si |
Nouveaux derives d'imidazoles carboxamides comme inhibiteurs de fructose -1,6-biphosphatase et compositions pharmaceutiques les contenant
|
ES2267400B1
(es)
|
2005-08-04 |
2008-03-01 |
Universitat De Valencia |
Composiciones pigmentarias en base acuosa para marcado policromatico de materiales inorganicos con laser.
|
EP1915367A1
(en)
|
2005-08-09 |
2008-04-30 |
AstraZeneca AB |
Heteroarylcarbamoylbenzene derivatives for the treatment of diabetes
|
DE602006018151D1
(de)
|
2005-08-10 |
2010-12-23 |
Glaxosmithkline Llc |
Xanthinderivate als selektive hm74a-agonisten
|
GB0516462D0
(en)
|
2005-08-10 |
2005-09-14 |
Smithkline Beecham Corp |
Novel compounds
|
CA2620570A1
(en)
|
2005-08-29 |
2007-03-08 |
Merck & Co., Inc. |
Niacin receptor agonists, compositions containing such compounds and methods of treatment
|
BRPI0615236A2
(pt)
|
2005-08-31 |
2011-05-10 |
Astellas Pharma Inc |
derivado de tiazol
|
JP2007063225A
(ja)
|
2005-09-01 |
2007-03-15 |
Takeda Chem Ind Ltd |
イミダゾピリジン化合物
|
WO2007028145A2
(en)
|
2005-09-02 |
2007-03-08 |
Dara Biosciences, Inc. |
Agents and methods for reducing protein tyrosine phosphatase 1b activity in the central nervous system
|
EP1931633A2
(en)
|
2005-09-05 |
2008-06-18 |
Ranbaxy Laboratories Limited |
Derivatives of 3-azabicyclo[3.1.0]hexane as dipeptidyl peptidase-iv inhibitors
|
GB2429975A
(en)
|
2005-09-08 |
2007-03-14 |
Univ Edinburgh |
1,5-substituted-1H-tetrazole 11beta-hydroxysteroid dehydrogenase type 1 inhibitors
|
MXPA05009633A
(es)
|
2005-09-08 |
2007-03-07 |
Silanes Sa De Cv Lab |
Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
|
CA2621949A1
(en)
|
2005-09-14 |
2007-03-22 |
Amgen Inc. |
Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders
|
DK1931654T3
(da)
|
2005-09-16 |
2009-07-27 |
Arena Pharm Inc |
Stofskiftemodulatorer og behandling af lidelser relateret dertil
|
CN101263140A
(zh)
|
2005-09-16 |
2008-09-10 |
阿斯利康(瑞典)有限公司 |
作为葡萄糖激酶活化剂的杂双环化合物
|
EP1931652A2
(en)
|
2005-09-21 |
2008-06-18 |
Incyte Corporation |
Amido compounds and their use as pharmaceuticals
|
JP5183479B2
(ja)
|
2005-09-29 |
2013-04-17 |
サノフイ |
フェニル基を有するフェニル−[1,2,4]−オキサジアゾール−5−オン誘導体、その製造方法、及び医薬品としてのその使用
|
GT200600429A
(es)
|
2005-09-30 |
2007-04-30 |
|
Compuestos organicos
|
GT200600428A
(es)
|
2005-09-30 |
2007-05-21 |
|
Compuestos organicos
|
JP4990783B2
(ja)
|
2005-09-30 |
2012-08-01 |
Msd株式会社 |
2−ヘテロアリール置換インドール誘導体
|
DE102005048897A1
(de)
|
2005-10-12 |
2007-04-19 |
Sanofi-Aventis Deutschland Gmbh |
Diacylindazol-derivate als Inhibitoren von Lipasen und Phospholipasen
|
TW200745031A
(en)
|
2005-10-13 |
2007-12-16 |
Merck & Co Inc |
Acyl indoles, compositions containing such compounds and methods of use
|
JP2009013065A
(ja)
|
2005-10-14 |
2009-01-22 |
Astellas Pharma Inc |
縮合へテロ環化合物
|
AU2006304434B2
(en)
|
2005-10-20 |
2012-04-05 |
Merck Sharp & Dohme Corp. |
Triazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
|
BRPI0618051A2
(pt)
|
2005-11-01 |
2011-08-16 |
Transtech Pharma Inc |
uso farmacêutico de amidas substituìdas
|
WO2007053345A1
(en)
|
2005-11-01 |
2007-05-10 |
Array Biopharma Inc. |
Glucokinase activators
|
CA2627910A1
(en)
|
2005-11-01 |
2007-05-10 |
Janssen Pharmaceutica N.V. |
Substituted cycloalkylpyrrolones as allosteric modulators of glucokinase
|
WO2007051810A2
(en)
|
2005-11-01 |
2007-05-10 |
Transtech Pharma |
Pharmaceutical use of substituted amides
|
EP1948645A1
(en)
|
2005-11-03 |
2008-07-30 |
Prosidion Limited |
Tricyclo substituted amides
|
US20080293741A1
(en)
|
2005-11-03 |
2008-11-27 |
Matthew Colin Thor Fyfe |
Tricyclo Substituted Amides as Glucokinase Modulators
|
BRPI0618062A2
(pt)
|
2005-11-03 |
2011-08-16 |
Prosidion Ltd |
composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, processo para a preparação de um composto
|
UA95613C2
(ru)
|
2005-11-09 |
2011-08-25 |
Уеллстат Терепьютикс Корпорейшн |
Соединения для лечения расстройсв метаболизма
|
ES2391109T3
(es)
|
2005-11-17 |
2012-11-21 |
Eli Lilly And Company |
Antagonistas del receptor de glucagón, preparación y usos terapéuticos
|
AU2006342449B2
(en)
|
2005-11-17 |
2012-03-01 |
Eli Lilly And Company |
Glucagon receptor antagonists, preparation and therapeutic uses
|
WO2007057768A2
(en)
|
2005-11-18 |
2007-05-24 |
Pfizer Products Inc. |
Sulfonyl derivatives
|
JP2009515997A
(ja)
|
2005-11-18 |
2009-04-16 |
タケダ サン ディエゴ インコーポレイテッド |
グルコキナーゼ活性剤
|
RU2443689C2
(ru)
|
2005-11-21 |
2012-02-27 |
Сионоги Энд Ко., Лтд. |
ГЕТЕРОЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ, ОБЛАДАЮЩИЕ ИНГИБИРУЮЩЕЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К 11β-ГИДРОКСИСТЕРОИДДЕГИДРОГЕНАЗЕ 1 ТИПА
|
MX2008006530A
(es)
|
2005-11-22 |
2008-09-25 |
Amgen Inc |
Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa tipo 1.
|
JP5230436B2
(ja)
|
2005-11-22 |
2013-07-10 |
イーライ リリー アンド カンパニー |
グルカゴン受容体アンタゴニスト、製造及び治療的使用
|
US7807702B2
(en)
|
2005-11-23 |
2010-10-05 |
Eli Lilly And Company |
Substituted thiophene carboxylic amide glucagon receptor antagonists, preparation and therapeutic uses
|
WO2007060992A1
(ja)
|
2005-11-25 |
2007-05-31 |
Kaneka Corporation |
メタボリックシンドロームもしくはインスリン抵抗性症候群の予防または改善剤
|
WO2007063928A1
(ja)
|
2005-11-30 |
2007-06-07 |
Toray Industries, Inc. |
新規な非環状アミンカルボキシアミド誘導体及びその塩
|
CN1978445B
(zh)
|
2005-12-02 |
2010-09-01 |
中国科学院上海药物研究所 |
一种可用作人源腺苷单核苷酸激活蛋白激酶激活剂的化合物及其制备方法和应用
|
WO2007070506A2
(en)
|
2005-12-14 |
2007-06-21 |
Amgen Inc. |
Diaza heterocyclic sulfonamide derivatives and their uses
|
US7943615B2
(en)
|
2005-12-14 |
2011-05-17 |
Merck Sharp & Dohme Corp. |
Fused aminopiperidines as dipeptidyl peptidase-4 inhibitors for the treatment or prevention of diabetes
|
EP1801098A1
(en)
|
2005-12-16 |
2007-06-27 |
Merck Sante |
2-Adamantylurea derivatives as selective 11B-HSD1 inhibitors
|
KR20080077024A
(ko)
|
2005-12-19 |
2008-08-20 |
트러스티즈 오브 터프츠 칼리지 |
소프트 단백질분해효소 억제자 및 이의 프로-소프트 폼
|
EP1966152A2
(en)
|
2005-12-20 |
2008-09-10 |
Takeda Pharmaceutical Company Limited |
Glucokinase activators
|
DE602006017259D1
(de)
|
2005-12-21 |
2010-11-11 |
Hoffmann La Roche |
Neues salz und polymorph des dpp-iv-hemmers
|
US7943613B2
(en)
|
2005-12-22 |
2011-05-17 |
High Point Pharmaceuticals, Llc |
Compounds, their preparation and use
|
EP1973885A1
(en)
|
2005-12-22 |
2008-10-01 |
Crystalgenomics, Inc. |
Aminopyrimidine derivatives inhibiting protein kinase activity, method for the preparation thereof and pharmaceutical composition containing same
|
RU2008129873A
(ru)
|
2005-12-23 |
2010-01-27 |
Новартис АГ (CH) |
Конденсированные гетероциклические соединения, полезные в качестве ингибиторов дпп-iv
|
US20090156465A1
(en)
|
2005-12-30 |
2009-06-18 |
Sattigeri Jitendra A |
Derivatives of beta-amino acid as dipeptidyl peptidase-iv inhibitors
|
WO2007081755A2
(en)
|
2006-01-09 |
2007-07-19 |
Metabasis Therapeutics, Inc. |
Indole-benzimidazole and indazole inhibitors of tyrosine phosphatases
|
UY30082A1
(es)
|
2006-01-11 |
2007-08-31 |
Boehringer Ingelheim Int |
Forma cristalina de 1-(1-metiletil)-4`-((2-fluoro-4-metoxifenil)metil)-5`- metil-1h-pirazol-3`-o-b-d-glucopiranosido, un metodo para su preparacion y el uso de la misma para preparar medicamentos
|
WO2007087150A2
(en)
|
2006-01-13 |
2007-08-02 |
Merck & Co., Inc. |
Triazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
|
EP1976509B1
(en)
|
2006-01-18 |
2014-12-17 |
Evolva SA |
Ppar modulators
|
KR20070077468A
(ko)
|
2006-01-23 |
2007-07-26 |
크리스탈지노믹스(주) |
단백질 키나아제 활성을 저해하는 이미다조피리딘 유도체,이의 제조방법 및 이를 함유하는 약학 조성물
|
CN101007798B
(zh)
|
2006-01-24 |
2011-01-26 |
中国人民解放军军事医学科学院毒物药物研究所 |
苯并间二氧杂环戊烯衍生物及其制备方法和医药用途
|
CN101007804B
(zh)
|
2006-01-25 |
2011-05-11 |
中国人民解放军军事医学科学院毒物药物研究所 |
1,3-苯并间二氧杂环戊烯-2,2-二羧酸衍生物、其制备方法和医疗用途
|
CA2636757A1
(en)
|
2006-01-25 |
2007-08-02 |
Tesfaye Biftu |
Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
CN101437512A
(zh)
|
2006-01-27 |
2009-05-20 |
阿雷生物药品公司 |
葡萄糖激酶活化剂
|
RU2008135125A
(ru)
|
2006-01-30 |
2010-03-10 |
Айрм Ллк (Bm) |
Соединения и композиции в качестве модуляторов ppar
|
AU2007210076A1
(en)
|
2006-01-30 |
2007-08-09 |
Irm Llc |
Polycyclic 1, 2, 3, 4 -tetrahydro- isoquinoline derivatives and compositions comprising them as PPAR modulators
|
CN101374841A
(zh)
|
2006-01-30 |
2009-02-25 |
Irm责任有限公司 |
作为ppar调节剂的螺咪唑衍生物
|
JP2009525333A
(ja)
|
2006-01-31 |
2009-07-09 |
インサイト・コーポレイション |
アミド化合物およびその医薬としての使用
|
PA8713501A1
(es)
|
2006-02-07 |
2009-09-17 |
Wyeth Corp |
INHIBIDORES DE 11-BETA HIDROXIESTEROIDE DEHIDROGENASA - 11ßHSD1
|
EP1983993A4
(en)
|
2006-02-07 |
2010-09-22 |
Merck Sharp & Dohme |
Niacin receptor agonists, compositions containing such compounds and method of treatment
|
US8044243B2
(en)
|
2006-02-13 |
2011-10-25 |
Wellstat Therapeutics Corporation |
Compounds for the treatment of metabolic disorders
|
DE102006006648A1
(de)
|
2006-02-14 |
2007-08-23 |
Merck Patent Gmbh |
Mandelsäurehydrazide
|
WO2007097931A2
(en)
|
2006-02-15 |
2007-08-30 |
Merck & Co., Inc. |
Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
WO2007093610A1
(en)
|
2006-02-15 |
2007-08-23 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture
|
WO2007099553A2
(en)
|
2006-02-27 |
2007-09-07 |
Cadila Healthcare Limited |
1,3-dioxane carboxylic acids
|
KR20080098615A
(ko)
|
2006-02-28 |
2008-11-11 |
웰스태트 테러퓨틱스 코포레이션 |
물질대사 장애의 치료용 화합물
|
WO2007099385A1
(en)
|
2006-03-01 |
2007-09-07 |
Glenmark Pharmaceuticals S.A. |
Dipeptidyl peptidase iv inhibitor compounds and compositions
|
US7834178B2
(en)
|
2006-03-01 |
2010-11-16 |
Bristol-Myers Squibb Company |
Triazine 11-beta hydroxysteroid dehydrogenase type 1 inhibitors
|
WO2007101270A1
(en)
|
2006-03-02 |
2007-09-07 |
Incyte Corporation |
MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
|
WO2007100027A1
(ja)
|
2006-03-02 |
2007-09-07 |
Daiichi Sankyo Company, Limited |
光学活性なチアゾリジンジオン誘導体
|
EP1993543A2
(en)
|
2006-03-03 |
2008-11-26 |
Merck & Co., Inc. |
Novel crystalline forms of antidiabetic compounds
|
US20070208001A1
(en)
|
2006-03-03 |
2007-09-06 |
Jincong Zhuo |
Modulators of 11- beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
|
US20070270492A1
(en)
|
2006-03-06 |
2007-11-22 |
Avestha Gengraine Technologies Pvt. Ltd. |
Nananoic acid derivatives as dipeptidyl peptidase inhibitors
|
US20080051452A1
(en)
|
2006-03-06 |
2008-02-28 |
Avestha Gengraine Technologies Pvt. Ltd. |
Hexanoic acid derivatives as dipeptidyl peptidase inhibitors
|
JP2009132620A
(ja)
|
2006-03-07 |
2009-06-18 |
Astellas Pharma Inc |
フェニルチアゾール誘導体
|
EP2001875A2
(en)
|
2006-03-08 |
2008-12-17 |
Takeda San Diego, Inc. |
Glucokinase activators
|
CA2645719A1
(en)
|
2006-03-09 |
2007-09-13 |
High Point Pharmaceuticals, Llc |
Compounds that modulate ppar activity, their preparation and use
|
CA2646429A1
(en)
|
2006-03-09 |
2007-09-13 |
Pharmacopeia, Inc. |
8-heteroarylpurine mnk2 inhibitors for treating metabolic disorders
|
WO2007105650A1
(ja)
|
2006-03-10 |
2007-09-20 |
Ajinomoto Co., Inc. |
4-ヒドロキシイソロイシン誘導体および同誘導体の製造方法
|
CA2646430A1
(en)
|
2006-03-14 |
2007-09-20 |
Amgen Inc. |
Bicyclic carboxylic acid derivatives useful for treating metabolic disorders
|
EP1996617A2
(en)
|
2006-03-15 |
2008-12-03 |
Novo Nordisk A/S |
Amylin derivatives
|
BRPI0708782A2
(pt)
|
2006-03-16 |
2011-06-14 |
Astellas Pharma Inc |
derivado de triazol ou um sal deste
|
JP5243696B2
(ja)
|
2006-03-17 |
2013-07-24 |
田辺三菱製薬株式会社 |
ベンゼン誘導体
|
JP2009530346A
(ja)
|
2006-03-21 |
2009-08-27 |
ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー |
メタボリックシンドロームの治療用のアダマンタン誘導体
|
KR20110007258A
(ko)
|
2006-03-22 |
2011-01-21 |
에프. 호프만-라 로슈 아게 |
11-베타-hsd-1로서의 피라졸
|
EP2004619A1
(en)
|
2006-03-23 |
2008-12-24 |
Amgen Inc. |
1-phenylsulfonyl-diaza heterocyclic amide compounds and their uses as modulators of hydroxsteroid dehydrogenases
|
CA2645639A1
(en)
|
2006-03-23 |
2007-10-04 |
Merck & Co. Inc. |
Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
|
BRPI0709171A2
(pt)
|
2006-03-24 |
2011-06-28 |
Array Biopharma Inc |
ativadores de glicoquinase, composição, usos dos referidos ativadores e métodos para preparação dos mesmos
|
FR2898892A1
(fr)
|
2006-03-24 |
2007-09-28 |
Genfit Sa |
Derives de n-(phenethyl)benzamide substitues,preparation et utilisations
|
FR2898894B1
(fr)
|
2006-03-24 |
2008-06-06 |
Genfit Sa |
Composes derives de n-(phenethyl)benzamide substitues, preparation et utilisations
|
JP2007291075A
(ja)
|
2006-03-27 |
2007-11-08 |
Sankyo Co Ltd |
新規化合物ステレニン及びその製造方法
|
TW200806669A
(en)
|
2006-03-28 |
2008-02-01 |
Merck & Co Inc |
Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
WO2007112347A1
(en)
|
2006-03-28 |
2007-10-04 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
DE102006014688A1
(de)
|
2006-03-28 |
2007-10-04 |
Sanofi-Aventis |
Azolopyridin-3-on-derivate als Inhibitoren von Lipasen und Phospholipasen
|
GB0606429D0
(en)
|
2006-03-30 |
2006-05-10 |
Novartis Ag |
Organic compounds
|
BRPI0710182A2
(pt)
|
2006-03-31 |
2012-08-07 |
Novartis Ag |
compostos orgÂnicos.
|
EP2004643A1
(en)
|
2006-03-31 |
2008-12-24 |
Novartis AG |
Organic compounds
|
WO2007114532A1
(en)
|
2006-04-03 |
2007-10-11 |
Industry-Academic Cooperation Foundation Gyeongsang National University |
Novel chalcone derivatives, pharmaceutically acceptable salt, method for preparation and uses thereof
|
MX2008012756A
(es)
|
2006-04-03 |
2009-03-05 |
Matrix Lab Ltd |
Inhibidores de dipeptidil peptidasa iv novedosos y procesos para su preparacion y composiciones farmaceuticas que los contienen.
|
CN101050194B
(zh)
|
2006-04-05 |
2013-08-21 |
上海恒瑞医药有限公司 |
双环辛烷类衍生物、其制备方法及其在医药上的用途
|
US20090221639A1
(en)
|
2006-04-06 |
2009-09-03 |
Lisa Sarah Bertram |
Heterocyclic GPCR Agonists
|
US8053447B2
(en)
|
2006-04-07 |
2011-11-08 |
High Point Pharmaceuticals, Llc |
11β-hydroxysteroid dehydrogenase type 1 active compounds
|
US7435833B2
(en)
|
2006-04-07 |
2008-10-14 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
|
KR20090047391A
(ko)
|
2006-04-07 |
2009-05-12 |
데벨로겐 악틴게젤샤프트 |
약제학적 조성물을 위한 Mnk1/Mnk2 억제 활성을 갖는티에노피리미딘
|
AR060404A1
(es)
|
2006-04-11 |
2008-06-11 |
Novartis Ag |
Compuestos organicos utiles como inhibidores de dipeptidil-peptidasa iv
|
GB0607196D0
(en)
|
2006-04-11 |
2006-05-17 |
Prosidion Ltd |
G-protein coupled receptor agonists
|
EP2010512A4
(en)
|
2006-04-11 |
2010-02-24 |
Merck & Co Inc |
NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
|
CA2649302A1
(en)
|
2006-04-12 |
2007-10-25 |
Wyeth |
Anilino-pyrimidine phenyl and benzothiophene analogs
|
EP2007734A1
(en)
|
2006-04-12 |
2008-12-31 |
Probiodrug AG |
Enzyme inhibitors
|
RU2419452C2
(ru)
|
2006-04-13 |
2011-05-27 |
Ипсен Фарма С.А.С. |
ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ hGLP-1, ЭКСЕНДИНА-4 И ИХ АНАЛОГОВ
|
JP2007284090A
(ja)
|
2006-04-14 |
2007-11-01 |
Dic Plastics Inc |
蓋体の係止構造および容器
|
WO2007119837A1
(ja)
|
2006-04-14 |
2007-10-25 |
Ajinomoto Co., Inc. |
リパーゼ阻害剤
|
PT2014652E
(pt)
|
2006-04-18 |
2014-11-12 |
Nippon Chemiphar Co |
Agente de ativação para o recetor ativado por proliferador de peroxissoma
|
PE20080188A1
(es)
|
2006-04-18 |
2008-03-10 |
Janssen Pharmaceutica Nv |
Derivados del acido benzoazepin-oxi-acetico como agonistas de ppar-delta usados para aumentar hdl-c, reducir ldl-c y reducir colesterol
|
WO2007120102A1
(en)
|
2006-04-19 |
2007-10-25 |
Astrazeneca Ab |
New substituted oxindole derivatives
|
PL2463283T3
(pl)
|
2006-04-20 |
2014-10-31 |
Pfizer Prod Inc |
Skondensowane fenyloamidowe związki heterocykliczne do zapobiegania i leczenia chorób pośredniczonych przez glukokinazę
|
EP2573111A1
(en)
|
2006-04-20 |
2013-03-27 |
Amgen Inc. |
GLP-1 compounds
|
US7842713B2
(en)
|
2006-04-20 |
2010-11-30 |
Pfizer Inc |
Fused phenyl amido heterocyclic compounds
|
WO2007122970A1
(ja)
|
2006-04-20 |
2007-11-01 |
Osaka University |
核内受容体に結合するリガンド
|
NZ571175A
(en)
|
2006-04-21 |
2011-10-28 |
Lilly Co Eli |
Cyclohexylpyrazole-lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
CN101426780B
(zh)
|
2006-04-21 |
2013-06-26 |
伊莱利利公司 |
作为11-β-羟基甾族化合物脱氢酶1的抑制剂的环己基咪唑内酰胺衍生物
|
MX2008013485A
(es)
|
2006-04-21 |
2008-10-30 |
Lilly Co Eli |
Derivados de lactamas de bifenilamida como inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1.
|
TW200815377A
(en)
|
2006-04-24 |
2008-04-01 |
Astellas Pharma Inc |
Oxadiazolidinedione compound
|
CN101432262B
(zh)
|
2006-04-24 |
2011-06-01 |
伊莱利利公司 |
作为11-β-羟类固醇脱氢酶1的抑制剂的环己基取代的吡咯烷酮类
|
EP2029529B1
(en)
|
2006-04-24 |
2010-07-07 |
Eli Lilly & Company |
Substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
WO2007122634A2
(en)
|
2006-04-24 |
2007-11-01 |
Jubilant Biosys Limited |
Pyrimidinediones as tyrosine kinase inhibitors
|
WO2007127688A2
(en)
|
2006-04-24 |
2007-11-08 |
Eli Lilly And Company |
Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
US8148534B2
(en)
|
2006-04-25 |
2012-04-03 |
Eli Lilly And Company |
Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
ATE471311T1
(de)
|
2006-04-25 |
2010-07-15 |
Lilly Co Eli |
Inhibitoren von11-beta- hydroxysteroiddehydrogenase 1
|
JP5189079B2
(ja)
|
2006-04-25 |
2013-04-24 |
イーライ リリー アンド カンパニー |
11−β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤
|
WO2007122411A1
(en)
|
2006-04-26 |
2007-11-01 |
Astrazeneca Ab |
Diazepan-1-yl-sulfonyl derivatives for the treatment of metabolic syndrome
|
WO2007126043A1
(ja)
|
2006-04-27 |
2007-11-08 |
Mitsubishi Tanabe Pharma Corporation |
チアゾール環を含むカルボン酸誘導体の医薬用途
|
CA2649577A1
(en)
|
2006-04-28 |
2007-11-08 |
Transtech Pharma, Inc. |
Benzamide glucokinase activators
|
WO2007125105A2
(en)
|
2006-04-28 |
2007-11-08 |
Transtech Pharma, Inc. |
Benzamide glucokinase activators
|
CN101448816B
(zh)
|
2006-04-28 |
2013-08-07 |
伊莱利利公司 |
作为11-β-羟类固醇脱氢酶1的抑制剂的哌啶基取代的吡咯烷酮类
|
EP1849785A1
(en)
|
2006-04-28 |
2007-10-31 |
Neuropharma, S.A. |
N-(2-Thiazolyl)-amide derivatives as GSK-3 inhibitors
|
EP2013163A1
(en)
|
2006-05-01 |
2009-01-14 |
Incyte Corporation |
Tetrasubstituted ureas as modulators of 11-beta hydroxyl steroid dehydrogenase type 1
|
JP2009167104A
(ja)
|
2006-05-02 |
2009-07-30 |
Taisho Pharmaceutical Co Ltd |
フェニル5−チオグリコシド化合物
|
EP1854806A1
(en)
|
2006-05-02 |
2007-11-14 |
MPG Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Thioglycosides as pharmaceutically active agents
|
JP2009167103A
(ja)
|
2006-05-02 |
2009-07-30 |
Taisho Pharmaceutical Co Ltd |
ピラゾリル5−チオグリコシド化合物
|
CA2810839A1
(en)
|
2006-05-04 |
2007-11-15 |
Boehringer Ingelheim International Gmbh |
A polymorphic form of 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(r)-amino-piperidin-1-yl)-xanthine
|
EP1852108A1
(en)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
DPP IV inhibitor formulations
|
WO2007131237A2
(en)
|
2006-05-05 |
2007-11-15 |
Isis Pharmaceuticals, Inc. |
Compounds and methods for modulating expression of ptp1b
|
WO2007128801A1
(en)
|
2006-05-08 |
2007-11-15 |
Novartis Ag |
Combination of organic compounds
|
JP5269766B2
(ja)
|
2006-05-09 |
2013-08-21 |
ノボ・ノルデイスク・エー/エス |
インスリン誘導体
|
JP5269767B2
(ja)
|
2006-05-09 |
2013-08-21 |
ノボ・ノルデイスク・エー/エス |
インスリン誘導体
|
AU2007250212A1
(en)
|
2006-05-11 |
2007-11-22 |
Sanofi-Aventis |
4,5-diphenyl-pyrimidinyl substituted carboxylic acids, method for the production and use thereof as medicaments
|
DE102006021878A1
(de)
|
2006-05-11 |
2007-11-15 |
Sanofi-Aventis |
Phenylamino-benzoxazol substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE102006021874B4
(de)
|
2006-05-11 |
2008-03-27 |
Sanofi-Aventis |
4,5-Diphenyl-pyrimidinyl-amino substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE102006021872B4
(de)
|
2006-05-11 |
2008-04-17 |
Sanofi-Aventis |
4,5-Diphenyl-pyrimidinyl-oxy oder -mercapto substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
US7851468B2
(en)
|
2006-05-15 |
2010-12-14 |
Cephalon, Inc. |
Substituted pyrazolo[3,4-d]pyrimidines
|
US7442808B2
(en)
|
2006-05-15 |
2008-10-28 |
Merck & Co., Inc. |
Antidiabetic bicyclic compounds
|
EP2019585A2
(en)
|
2006-05-16 |
2009-02-04 |
Merck & Co., Inc. |
Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
|
WO2007136603A2
(en)
|
2006-05-16 |
2007-11-29 |
Merck & Co., Inc. |
Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
US7838544B2
(en)
|
2006-05-17 |
2010-11-23 |
Incyte Corporation |
Heterocyclic inhibitors of 11-β hydroxyl steroid dehydrogenase type 1 and methods of using the same
|
CA2651598A1
(en)
|
2006-05-18 |
2007-11-29 |
Wellstat Therapeutics Corporation |
Compounds for the treatment of metabolic disorders
|
WO2007136116A2
(en)
|
2006-05-19 |
2007-11-29 |
Taisho Pharmaceutical Co., Ltd. |
C-phenyl glycitol compound for the treatment of diabetes
|
WO2007135427A1
(en)
|
2006-05-23 |
2007-11-29 |
Astrazeneca Ab |
1,4-disubstituted piperazine and 1,4-disubstituted azepane as 11 -beta-hydroxysteroid dehydrogenase 1 inhibitors
|
WO2007140191A2
(en)
|
2006-05-23 |
2007-12-06 |
Theracos, Inc. |
Glucose transport inhibitors and methods of use
|
ES2344086T3
(es)
|
2006-05-23 |
2010-08-17 |
F. Hoffmann-La Roche Ag |
Derivados de piridopirimidinona.
|
JP5105297B2
(ja)
|
2006-05-25 |
2012-12-26 |
味の素株式会社 |
Ppar活性調節剤
|
WO2007140230A2
(en)
|
2006-05-26 |
2007-12-06 |
Nestec S.A. |
Methods of use and nutritional compositions of touchi extract
|
BRPI0712557A2
(pt)
|
2006-05-26 |
2013-07-02 |
Novartis Ag |
inibidores de aldosterona sintase e/ou 11 beta-hidrolase
|
US8008332B2
(en)
|
2006-05-31 |
2011-08-30 |
Takeda San Diego, Inc. |
Substituted indazoles as glucokinase activators
|
AU2007267191B2
(en)
|
2006-06-01 |
2010-08-26 |
F. Hoffmann-La Roche Ag |
Thiazole derivatives
|
FR2901792A1
(fr)
|
2006-06-06 |
2007-12-07 |
Negma Lerads Soc Par Actions S |
DERIVES ACTIVATEURS DE PPARs, PROCEDE DE PREPARATION ET APPLICATION EN THERAPEUTIQUE
|
JP2009190971A
(ja)
|
2006-06-06 |
2009-08-27 |
Mitsubishi Tanabe Pharma Corp |
2−シアノピロリジン誘導体
|
US20070287674A1
(en)
|
2006-06-08 |
2007-12-13 |
Hej Research Institute Of Chemistry |
New treatment of diabetes mellitus
|
WO2007145834A2
(en)
|
2006-06-08 |
2007-12-21 |
Amgen Inc. |
Benzamide derivatives and uses related thereto
|
TW200808695A
(en)
|
2006-06-08 |
2008-02-16 |
Amgen Inc |
Benzamide derivatives and uses related thereto
|
WO2007146761A2
(en)
|
2006-06-12 |
2007-12-21 |
Neurogen Corporation |
Diaryl pyrimidinones and related compounds
|
WO2008035359A2
(en)
|
2006-06-12 |
2008-03-27 |
Cadila Healthcare Limited |
Oximinophenoxyalkanoic acid and phenylalkanoic acid derivatives
|
WO2007144394A2
(en)
|
2006-06-16 |
2007-12-21 |
High Point Pharmaceuticals, Llc. |
Pharmaceutical use of substituted piperidine carboxamides
|
WO2007149865A2
(en)
|
2006-06-19 |
2007-12-27 |
University Of Utah Research Foundation |
Methods and compositions related to inhibition of ceramide synthesis
|
WO2007148185A2
(en)
|
2006-06-21 |
2007-12-27 |
Pfizer Products Inc. |
Substituted 3 -amino- pyrrolidino-4 -lactams as dpp inhibitors
|
JP5274455B2
(ja)
|
2006-06-23 |
2013-08-28 |
インサイト コーポレイション |
Hm74aアゴニストとしてのプリノン誘導体
|
DE102006028862A1
(de)
|
2006-06-23 |
2007-12-27 |
Merck Patent Gmbh |
3-Amino-imidazo[1,2-a]pyridinderivate
|
AU2007260851B2
(en)
|
2006-06-23 |
2013-01-17 |
Incyte Corporation |
Purinone derivatives as HM74a agonists
|
TW200815418A
(en)
|
2006-06-27 |
2008-04-01 |
Astrazeneca Ab |
New compounds I
|
TWI354668B
(en)
|
2006-06-27 |
2011-12-21 |
Takeda Pharmaceutical |
Fused cyclic compounds
|
PE20080212A1
(es)
|
2006-06-27 |
2008-04-25 |
Sanofi Aventis |
Derivados de ureas de piperidina o pirrolidina como moduladores de la 11b-hidroxiesteroide deshidrogenasa tipo 1 (11bhsd1)
|
PE20080344A1
(es)
|
2006-06-27 |
2008-06-09 |
Sanofi Aventis |
Compuestos 8-azabiciclo[3.2.1]oct-8-il-1,2,3,4-tetrahidroquinolina sustituidos como inhibidores 11b-hsd1
|
TW200815417A
(en)
|
2006-06-27 |
2008-04-01 |
Astrazeneca Ab |
New compounds II
|
US20080004281A1
(en)
|
2006-06-28 |
2008-01-03 |
Kalypsys, Inc. |
Methods for the modulation of crp by the selective modulation of ppar delta
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
US20080004325A1
(en)
|
2006-06-29 |
2008-01-03 |
Wyeth |
PTP1B inhibitors
|
JP5152519B2
(ja)
|
2006-06-29 |
2013-02-27 |
大正製薬株式会社 |
C−フェニル1−チオグルシト−ル化合物
|
MX2008016426A
(es)
|
2006-07-05 |
2009-01-19 |
Hoffmann La Roche |
Derivados de alquilpiridazina como inhibidores de 11 beta hidroxiesteroide deshidrogenasa tipo 1(11b-hsd 1).
|
TW200811140A
(en)
|
2006-07-06 |
2008-03-01 |
Arena Pharm Inc |
Modulators of metabolism and the treatment of disorders related thereto
|
US7888504B2
(en)
|
2006-07-06 |
2011-02-15 |
Bristol-Myers Squibb Company |
Glucokinase activators and methods of using same
|
TW200811147A
(en)
|
2006-07-06 |
2008-03-01 |
Arena Pharm Inc |
Modulators of metabolism and the treatment of disorders related thereto
|
US7910747B2
(en)
|
2006-07-06 |
2011-03-22 |
Bristol-Myers Squibb Company |
Phosphonate and phosphinate pyrazolylamide glucokinase activators
|
JP5194588B2
(ja)
|
2006-07-06 |
2013-05-08 |
大正製薬株式会社 |
1−チオ−d−グルシトール誘導体を有効成分として含有する糖尿病の予防又は治療剤
|
EP2046753A2
(en)
|
2006-07-06 |
2009-04-15 |
Brystol-Myers Squibb Company |
Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors
|
CN101100458A
(zh)
|
2006-07-07 |
2008-01-09 |
上海艾力斯医药科技有限公司 |
具有PPARγ激动剂活性的双苯并咪唑衍生物及其应用
|
US20080009534A1
(en)
|
2006-07-07 |
2008-01-10 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
|
US7795291B2
(en)
|
2006-07-07 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method
|
FR2903404B1
(fr)
|
2006-07-10 |
2008-08-22 |
Servier Lab |
Nouveaux derives tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
EP2043744A2
(en)
|
2006-07-13 |
2009-04-08 |
SmithKline Beecham Corporation |
Chemical compounds
|
CA2657078A1
(en)
|
2006-07-13 |
2008-01-17 |
High Point Pharmaceuticals, Llc |
11beta-hydroxysteroid dehydrogenase type 1 active compounds
|
EP1878721A1
(en)
|
2006-07-13 |
2008-01-16 |
Novo Nordisk A/S |
4-Piperidylbenzamides as 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors
|
FR2903695B1
(fr)
|
2006-07-13 |
2008-10-24 |
Merck Sante Soc Par Actions Si |
Utilisation de derives d'imidazole activateurs de l'ampk, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
JP5372318B2
(ja)
|
2006-07-14 |
2013-12-18 |
パナソニック株式会社 |
電気化学キャパシタの製造方法
|
WO2008008547A2
(en)
|
2006-07-14 |
2008-01-17 |
Ams Research Corporation |
Balloon dilation for implantable prosthesis
|
DE102006033140A1
(de)
|
2006-07-18 |
2008-01-24 |
Merck Patent Gmbh |
Aminoindazolharnstoffderivate
|
US7666888B2
(en)
|
2006-07-20 |
2010-02-23 |
Amgen Inc. |
Substituted azole aromatic heterocycles as inhibitors of 11β-HSD-1
|
US8594202B2
(en)
|
2006-07-21 |
2013-11-26 |
Vidyo, Inc. |
Systems and methods for signaling and performing temporal level switching in scalable video coding
|
WO2008010238A2
(en)
|
2006-07-21 |
2008-01-24 |
Lupin Limited |
Antidiabetic azabicyclo [3. 1. 0] hexan compounds
|
FR2903984B1
(fr)
|
2006-07-24 |
2008-10-03 |
Genfit Sa |
Derives d'imidazolones substitues, preparation et utilisations
|
US20100022589A1
(en)
|
2006-07-27 |
2010-01-28 |
Mccoull William |
Pyridine-3-carboxamide compounds and their use for inhibiting 11-beta-hydroxysteroid dehydrogenase
|
TWI418556B
(zh)
|
2006-07-27 |
2013-12-11 |
Mitsubishi Tanabe Pharma Corp |
吲哚衍生物
|
JP2008031064A
(ja)
|
2006-07-27 |
2008-02-14 |
Astellas Pharma Inc |
ジアシルピペラジン誘導体
|
TWI403516B
(zh)
|
2006-07-27 |
2013-08-01 |
Chugai Pharmaceutical Co Ltd |
To replace spirocyclic alcohol derivatives, and its use as a therapeutic agent for diabetes
|
TWI432446B
(zh)
|
2006-07-27 |
2014-04-01 |
Chugai Pharmaceutical Co Ltd |
稠環螺酮縮醇衍生物、及其做為糖尿病治療藥之使用
|
US20080027014A1
(en)
|
2006-07-28 |
2008-01-31 |
Tanabe Seiyaku Co., Ltd. |
Novel SGLT inhibitors
|
WO2008016730A2
(en)
|
2006-08-02 |
2008-02-07 |
Targeted Molecular Diagnostics, Llc |
Compositions and methods for reducing cellular fat
|
US8377971B2
(en)
|
2006-08-03 |
2013-02-19 |
Trustees Of Tufts College |
Non-flushing niacin analogues, and methods of use thereof
|
US8492378B2
(en)
|
2006-08-03 |
2013-07-23 |
Takeda Pharmaceutical Company Limited |
GSK-3β inhibitor
|
WO2008016175A1
(fr)
|
2006-08-03 |
2008-02-07 |
Nippon Chemiphar Co., Ltd. |
Agent activant de récepteur activé par les proliférateurs des peroxysomes
|
TW200817424A
(en)
|
2006-08-04 |
2008-04-16 |
Daiichi Sankyo Co Ltd |
Benzylphenyl glucopyranoside derivatives
|
WO2008019309A1
(en)
|
2006-08-04 |
2008-02-14 |
Metabasis Therapeutics, Inc. |
Novel inhibitors of fructose 1,6-bisphosphatase
|
KR100826108B1
(ko)
|
2006-08-04 |
2008-04-29 |
한국화학연구원 |
퓨란-2-카복실산 유도체 및 그의 제조 방법
|
EP1887006A1
(en)
|
2006-08-07 |
2008-02-13 |
Krka |
Polymorphic forms of rosiglitazone base
|
US8071583B2
(en)
|
2006-08-08 |
2011-12-06 |
Boehringer Ingelheim International Gmbh |
Pyrrolo[3,2-D] pyrimidines as DPP-IV inhibitors for the treatment of diabetes mellitus
|
WO2008022015A2
(en)
|
2006-08-11 |
2008-02-21 |
Trustees Of Tufts College |
Retro-inverso incretin analogues, and methods of use thereof
|
US8039441B2
(en)
|
2006-08-15 |
2011-10-18 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted cyclopropylbenzene derivatives, pharmaceutical compositions containing such compounds, their use as SGLT inhibitors and process for their manufacture
|
EP2057188B1
(en)
|
2006-08-17 |
2013-07-31 |
Amylin Pharmaceuticals, LLC |
Dpp-iv resistant gip hybrid polypeptides with selectable properties
|
JP2009256208A
(ja)
|
2006-08-17 |
2009-11-05 |
Dainippon Sumitomo Pharma Co Ltd |
フタリド誘導体またはその薬学的に許容される塩
|
CN101528729A
(zh)
|
2006-08-23 |
2009-09-09 |
辉瑞产品公司 |
作为gsk-3抑制剂的嘧啶酮化合物
|
US7727978B2
(en)
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
CA2661503A1
(en)
|
2006-08-25 |
2008-02-28 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of 11.beta. -hydroxysteroid dehydrogenase type 1
|
WO2008029217A2
(en)
|
2006-08-29 |
2008-03-13 |
Orchid Research Laboratories Limited |
Dipeptidyl peptidase iv inhibitors
|
JP2010501629A
(ja)
|
2006-08-30 |
2010-01-21 |
ビオヴィトルム・アクチボラゲット(プブリクト) |
Gpr119関連障害を治療するためのピリジン化合物
|
CL2007002499A1
(es)
|
2006-08-30 |
2008-03-14 |
Phenomix Corp |
Sales citrato y tartrato de compuestos derivados de acido pirrolidinilaminoacetilpirrolidinboronico, inhibidores de dpp-iv; metodo de preparacion; forma solida; combinacion farmaceutica, util para el tratamiento de diabetes.
|
WO2008028188A2
(en)
|
2006-09-01 |
2008-03-06 |
The Ticket Reserve |
Demand aggregation for future items contingent upon threshold demand
|
AU2007290359B2
(en)
|
2006-09-01 |
2012-09-20 |
Vertex Pharmaceuticals Incorporated |
5- (2-furyl)-1, 3-thiazole derivatives useful as inhibitors of phosphatidylinositol 3-kinase
|
JP2008063256A
(ja)
|
2006-09-06 |
2008-03-21 |
Astellas Pharma Inc |
β‐アミノ酸誘導体
|
CA2662242C
(en)
|
2006-09-07 |
2012-06-12 |
Amgen Inc. |
Benzo-fused compounds for use in treating metabolic disorders
|
WO2008028662A1
(en)
|
2006-09-07 |
2008-03-13 |
Santhera Pharmaceuticals (Schweiz) Ag |
N-[1-(3-amino-4-phenyl-butyryl)-4-hydroxy-pyrrolidin-2-ylmethyl}-propionamide and related compounds as dpp-iv inhibitors for the treatment of type 2 diabetes mellitus
|
EP2064193A1
(en)
|
2006-09-07 |
2009-06-03 |
Amgen, Inc |
Heterocyclic gpr40 modulators
|
CA2663189A1
(en)
|
2006-09-12 |
2008-03-20 |
Pfizer Products Inc. |
Benzimidazolone derivatives
|
WO2008033455A2
(en)
|
2006-09-13 |
2008-03-20 |
The Institutes For Pharmaceutical Discovery, Llc |
Biphenyl and heteroaryl phenyl derivatives as protein tyrosine phosphatases inhibitors
|
EA017799B1
(ru)
|
2006-09-13 |
2013-03-29 |
Такеда Фармасьютикал Компани Лимитед |
Применение 2-[6-(3-аминопиперидин-1-ил)-3-метил-2,4-диоксо-3,4-дигидро-2н-пиримидин-1-илметил]-4-фторбензонитрила
|
WO2008033932A2
(en)
|
2006-09-13 |
2008-03-20 |
The Institutes For Pharmaceutical Discovery, Llc |
Biarylthiazole carboxylic acid derivatives as protein tyrosine phosphatase-ib inhibitors
|
WO2008033934A1
(en)
|
2006-09-13 |
2008-03-20 |
The Institutes For Pharmaceutical Discovery, Llc |
Substituted heteroaryl carboxylic acid derivatives as ptb-1b inhibitors
|
WO2008033931A1
(en)
|
2006-09-13 |
2008-03-20 |
The Institutes For Pharmaceutical Discovery, Llc |
Para-xylylene carboxylic acids and isothiazolones useful as protein tyrosine phosphatases (ptps) in particular ptp-ib
|
WO2008034032A2
(en)
|
2006-09-14 |
2008-03-20 |
Azevan Pharmaceuticals, Inc. |
Beta-lactam cannabinoid receptor modulators
|
EP2074130A1
(en)
|
2006-09-21 |
2009-07-01 |
Boehringer Ingelheim International GmbH |
Glucopyranosyl-substituted difluorobenzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
CA2663074A1
(en)
|
2006-09-22 |
2008-03-27 |
Novo Nordisk A/S |
Protease resistant insulin analogues
|
TWI499414B
(zh)
|
2006-09-29 |
2015-09-11 |
Lexicon Pharmaceuticals Inc |
鈉與葡萄糖第2型共同運輸體(co-transporter 2)的抑制物與其應用方法
|
MX2009003169A
(es)
|
2006-09-29 |
2009-04-03 |
Hoffmann La Roche |
Derivados de sulfonamida.
|
WO2008039882A1
(en)
|
2006-09-30 |
2008-04-03 |
Sanofi-Aventis U.S. Llc |
A combination of niacin and a prostaglandin d2 receptor antagonist
|
TW200821284A
(en)
|
2006-10-03 |
2008-05-16 |
Merck & Co Inc |
Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
|
DK2084182T3
(da)
|
2006-10-03 |
2013-11-04 |
Cadila Healthcare Ltd |
Antidiabetiske forbindelser
|
AR063028A1
(es)
|
2006-10-06 |
2008-12-23 |
Banyu Pharma Co Ltd |
Derivados heterociclicos de piridin-2-carboxamida activadores de glucoquinasas, utiles para el tratamiento de diabetes y obesidad y composiciones farmaceuticas que los contienen.
|
WO2008044656A1
(fr)
|
2006-10-06 |
2008-04-17 |
Taisho Pharmaceutical Co., Ltd. |
Dérivé d'imidazolidinone
|
WO2008040995A1
(en)
|
2006-10-07 |
2008-04-10 |
Peakdale Molecular Limited |
Indazoles for use as dpp-iv inhibitors
|
ES2430821T3
(es)
|
2006-10-10 |
2013-11-21 |
Amgen Inc. |
Compuestos de N-arilpirazol para usar contra la diabetes
|
EP1911747A1
(en)
|
2006-10-11 |
2008-04-16 |
Laboratorios del Dr. Esteve S.A. |
Sulfonamide substituted pyrazoline compounds, their preparation and use as CB1 modulators
|
WO2008044700A1
(fr)
|
2006-10-11 |
2008-04-17 |
Takeda Pharmaceutical Company Limited |
INHIBITEUR DE LA GSK-3β
|
US20080107725A1
(en)
|
2006-10-13 |
2008-05-08 |
Albano Antonio A |
Pharmaceutical Solid Dosage Forms Comprising Amorphous Compounds Micro-Embedded in Ionic Water-Insoluble Polymers
|
BRPI0719523A2
(pt)
|
2006-10-13 |
2015-06-16 |
Chugai Pharmaceutical Co Ltd |
Derivado de espirocetal de tioglicose e uso deste como agente terapêutico para diabetes
|
US7705005B2
(en)
|
2006-10-13 |
2010-04-27 |
Glaxo Group Limited |
Bicyclic heteroaromatic compounds
|
DE102006048728A1
(de)
|
2006-10-16 |
2008-04-17 |
Merck Patent Gmbh |
3-Amino-imidazo{1,2-a]pyridinderivate
|
EP2077267A4
(en)
|
2006-10-18 |
2010-04-07 |
Takeda Pharmaceutical |
FUSED HETEROCYCLIC COMPOUND
|
WO2008046758A2
(en)
|
2006-10-19 |
2008-04-24 |
F. Hoffmann-La Roche Ag |
Imidazolone and imidazolidinone derivatives as 11b-hsd1 inhibitors for diabetes
|
BRPI0717722A2
(pt)
|
2006-10-19 |
2013-10-29 |
Takeda Pharmaceutical |
Composto ou um sal do mesmo, pró-droga, ativador de glicoquinase, agente farmacêutico, métodos para ativar uma glicoquinase em um mamífero e para a profilaxia ou o tratamento de diabetes ou obesidade em um mamífero, e, uso do composto ou uma pró-droga do mesmo
|
JP2010506915A
(ja)
|
2006-10-20 |
2010-03-04 |
メルク エンド カムパニー インコーポレーテッド |
ナイアシン受容体アゴニスト、そのような化合物を含む組成物、及び治療方法
|
TW200825063A
(en)
|
2006-10-23 |
2008-06-16 |
Astrazeneca Ab |
Chemical compounds
|
KR100812538B1
(ko)
|
2006-10-23 |
2008-03-11 |
한올제약주식회사 |
약물 제어방출형 메트포르민-글리메피리드 복합제제
|
US20080103201A1
(en)
|
2006-10-26 |
2008-05-01 |
Wijayabandara Mirihanage Don J |
Novel alpha-Glucosidase inhibitor from Tabernaemontana dichotoma
|
SA07280576B1
(ar)
|
2006-10-26 |
2011-06-22 |
استرازينيكا ايه بي |
مركبات بنزويل أمينو سيكليل غير متجانسة بأعتبارها عوامل منشطة للجلوكوكيناز
|
WO2008049711A1
(en)
|
2006-10-27 |
2008-05-02 |
Novo Nordisk A/S |
Peptide extended insulins
|
CA2667550A1
(en)
|
2006-10-27 |
2008-05-02 |
Boehringer Ingelheim International Gmbh |
Crystalline form of 4-(.beta.-d-glucopyranos-1-yl)-1-methyl-2-[4-((s)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments
|
WO2008054674A2
(en)
|
2006-10-31 |
2008-05-08 |
Merck & Co., Inc. |
Antidiabetic bicyclic compounds
|
EP2079467B1
(en)
|
2006-10-31 |
2015-11-18 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
WO2008057855A2
(en)
|
2006-11-01 |
2008-05-15 |
Bristol-Myers Squibb Company |
Heterocyclic compounds as modulators of glucocorticoid receptor, ap-i, and/or np-kappa-b activity
|
EP2094692B1
(en)
|
2006-11-01 |
2012-11-28 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, ap-1 and/or nf-kappab activity and use thereof
|
US8198311B2
(en)
|
2006-11-01 |
2012-06-12 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
CA2667211A1
(en)
|
2006-11-01 |
2008-05-08 |
Pronova Biopharma Norge As |
Alpha-substituted omega-3 lipids that are activators or modulators of the peroxisome proliferators-activated receptor (ppar)
|
WO2008057859A2
(en)
|
2006-11-01 |
2008-05-15 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, ap-i and/or nf-kappab activity and use thereof
|
US7968577B2
(en)
|
2006-11-01 |
2011-06-28 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
WO2008053446A2
(en)
|
2006-11-02 |
2008-05-08 |
Piramal Life Sciences Limited |
Benzoxazepine compounds, their preparation and use
|
NZ576750A
(en)
|
2006-11-02 |
2012-01-12 |
Vertex Pharma |
Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases
|
TW200827346A
(en)
|
2006-11-03 |
2008-07-01 |
Astrazeneca Ab |
Chemical compounds
|
EP1918285A1
(en)
|
2006-11-03 |
2008-05-07 |
Merck Sante |
Diazepane-acetamide derivatives as selective 11beta-HSD1 inhibitors
|
US7879806B2
(en)
|
2006-11-06 |
2011-02-01 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzyl-benzonitrile derivates, medicaments containing such compounds, their use and process for their manufacture
|
EP1921080B1
(en)
|
2006-11-07 |
2009-08-05 |
Sanofi-Aventis |
Subsitituted 8-piperidinyl-2-pyridinyl-pyrimido(1,2-a)pyrimidin-6-one and 8-piperidinyl-2-pyrimidinyl-pyrimido(1,2-a)pyrimidin-6-one derivatives
|
EP2081569A2
(en)
|
2006-11-09 |
2009-07-29 |
Boehringer Ingelheim International GmbH |
Combination therapy with sglt-2 inhibitors and their pharmaceutical compositions
|
JP2010043001A
(ja)
|
2006-11-09 |
2010-02-25 |
Sanwa Kagaku Kenkyusho Co Ltd |
Glp−1誘導体とその用途
|
WO2008060488A1
(en)
|
2006-11-14 |
2008-05-22 |
Merck & Co., Inc. |
Tricyclic heteroaromatic compounds as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
JP4969417B2
(ja)
|
2006-11-14 |
2012-07-04 |
参天製薬株式会社 |
(置換フェニル若しくは置換複素環)カルボニルオキシ低級アルキル基とエステル構造を導入したフェニル基を置換基として有する新規1,2−ジヒドロキノリン誘導体
|
US7750048B2
(en)
|
2006-11-15 |
2010-07-06 |
Janssen Pharmaceutica Nv |
GPR40 agonists
|
JP5633952B2
(ja)
|
2006-11-17 |
2014-12-03 |
松谷化学工業株式会社 |
D−プシコースを有効成分とするグルコキナーゼの核から細胞質への移行の促進剤
|
WO2008062273A2
(en)
|
2006-11-20 |
2008-05-29 |
Cadila Pharmaceuticals Limited |
Solid oral dosage form having antidiabetic drug combination
|
JP2010510317A
(ja)
|
2006-11-20 |
2010-04-02 |
ブリストル−マイヤーズ スクイブ カンパニー |
ジペプチジルペプチダーゼivの阻害剤としての7,8−ジヒドロ−1,6−ナフチリジン−5(6h)−オンおよび関連二環式化合物、および方法
|
EP2096111A1
(en)
|
2006-11-20 |
2009-09-02 |
Japan Tobacco Inc. |
Pyrazoles and use thereof as drugs
|
WO2008061355A1
(en)
|
2006-11-24 |
2008-05-29 |
Matregen Corp. |
Glp-1 depot systems, and methods of manufacture and uses thereof
|
JP5176964B2
(ja)
|
2006-11-29 |
2013-04-03 |
ユーハ味覚糖株式会社 |
ジペプチジルペプチダーゼiv阻害剤
|
JP4125768B2
(ja)
|
2006-11-30 |
2008-07-30 |
富士産業株式会社 |
α−グルコシダーゼ阻害剤
|
US8367708B2
(en)
|
2006-12-01 |
2013-02-05 |
Msd K.K. |
Phenyl-isoxazol-3-ol derivative
|
TW200838526A
(en)
|
2006-12-01 |
2008-10-01 |
Astellas Pharma Inc |
Carboxylic acid derivatives
|
CN103086936A
(zh)
|
2006-12-02 |
2013-05-08 |
财团法人首尔大学校产学协力财团 |
作为ppar配体的芳基化合物及其用途
|
JP5298025B2
(ja)
|
2006-12-04 |
2013-09-25 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
抗糖尿病薬としてのチエニル含有グリコピラノシル誘導体
|
UY30730A1
(es)
|
2006-12-04 |
2008-07-03 |
Mitsubishi Tanabe Pharma Corp |
Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno
|
AR064106A1
(es)
|
2006-12-05 |
2009-03-11 |
Bayer Schering Pharma Ag |
Derivados de 2,3-dihidroimidazo [1,2-c] quinazolina sustituida utiles para el tratamiento de enfermedades y trastornos hiper-proliferativos asociados con la angiogenesis
|
MX2009005264A
(es)
|
2006-12-06 |
2009-05-28 |
Boehringer Ingelheim Int |
Mimeticos de glucocorticoides, metodos para su fabricacion, composiciones farmaceuticas y usos de los mismos.
|
JP5330260B2
(ja)
|
2006-12-06 |
2013-10-30 |
スミスクライン ビーチャム コーポレーション |
二環式化合物ならびに抗糖尿病薬としての使用
|
DE102006058236A1
(de)
|
2006-12-11 |
2008-06-12 |
Merck Patent Gmbh |
Indolizinderivate
|
WO2008071169A2
(de)
|
2006-12-11 |
2008-06-19 |
Universitätsklinikum Schleswig-Holstein |
Verfahren zur herstellung spezifischer inhibitoren der 11beta-hydroxysteroid-dehydrogenase, insbesondere des typs 1, mit nor-oleanan- oder nor-ursan-grundgerüsten
|
EP1932843A1
(en)
|
2006-12-14 |
2008-06-18 |
sanofi-aventis |
Sulfonyl-phenyl-2H-(1,2,4) oxadiazole-5-one derivatives, processes for their preparation and their use as pharmaceuticals
|
EP2112880A4
(en)
|
2006-12-14 |
2011-12-21 |
Merck Sharp & Dohme |
ACYL-BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND PROCESSING METHODS
|
US7902248B2
(en)
|
2006-12-14 |
2011-03-08 |
Hoffmann-La Roche Inc. |
Oxime glucokinase activators
|
JPWO2008072726A1
(ja)
|
2006-12-14 |
2010-04-02 |
大正製薬株式会社 |
1−フェニル 1−チオ−d−グルシト−ル誘導体
|
CA2672269A1
(en)
|
2006-12-18 |
2008-06-26 |
Novartis Ag |
Organic compounds
|
MX2009006481A
(es)
|
2006-12-18 |
2009-06-26 |
Novartis Ag |
Derivados de imidazol 1-sustituidos, y su uso como inhibidores de la sintasa de aldosterona.
|
ES2446269T3
(es)
|
2006-12-19 |
2014-03-06 |
The Board Of Trustees Of The University Of Illinois |
3-Benzofuranil-4-indolil-maleimidas como potentes inhibidores de GSK-3 para trastornos neurodegenerativos
|
JPWO2008075741A1
(ja)
|
2006-12-20 |
2010-04-15 |
国立大学法人 長崎大学 |
糖尿病治療剤及び予防剤
|
JP5419706B2
(ja)
|
2006-12-20 |
2014-02-19 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼアクチベーター
|
EP1939187A1
(en)
|
2006-12-20 |
2008-07-02 |
Sanofi-Aventis |
Substituted heteroaryl pyridopyrimidone derivatives
|
US20100029688A1
(en)
|
2006-12-20 |
2010-02-04 |
Wood Harold B |
Bipiperidinyl compounds, compositions containing such compounds and methods of treatment
|
EP1935420A1
(en)
|
2006-12-21 |
2008-06-25 |
Merck Sante |
2-Adamantyl-butyramide derivatives as selective 11beta-HSD1 inhibitors
|
CN101595104A
(zh)
|
2006-12-21 |
2009-12-02 |
阿斯利康(瑞典)有限公司 |
作为glk活化剂的新的晶态化合物
|
US20100029710A1
(en)
|
2006-12-21 |
2010-02-04 |
Pfizer Products Inc. |
COMPOUNDS HAVING BOTH ANGIOTENSIN II RECEPTOR ANTAGONISM AND PPARy ACTIVATING ACTIVITIES
|
JP2010513357A
(ja)
|
2006-12-22 |
2010-04-30 |
ノバルティス アーゲー |
Dpp−iv阻害剤としての1−アミノメチル−1−フェニル−シクロヘキサン誘導体
|
TW200831081A
(en)
|
2006-12-25 |
2008-08-01 |
Kyorin Seiyaku Kk |
Glucokinase activator
|
JP2008156318A
(ja)
|
2006-12-26 |
2008-07-10 |
Dainippon Sumitomo Pharma Co Ltd |
1,3,4−オキサジアゾール−2−オン誘導体
|
WO2008088540A2
(en)
|
2006-12-26 |
2008-07-24 |
Amgen Inc. |
N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
|
EP2119719A1
(en)
|
2006-12-26 |
2009-11-18 |
Daiichi Sankyo Company, Limited |
Thiazepine derivative
|
EP1939192A1
(en)
|
2006-12-28 |
2008-07-02 |
Neuropharma S.A. |
Cyclopentanone derivatives, method of synthesis and uses thereof
|
ES2627221T3
(es)
|
2006-12-28 |
2017-07-27 |
Rigel Pharmaceuticals, Inc. |
Compuestos de heterocicloalquiloxibenzamida N-sustituidos y métodos de uso
|
US7638541B2
(en)
|
2006-12-28 |
2009-12-29 |
Metabolex Inc. |
5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
|
EP1939191A1
(en)
|
2006-12-28 |
2008-07-02 |
Neuropharma S.A. |
Furan derivatives, method of synthesis and uses thereof
|
US7795228B2
(en)
|
2006-12-28 |
2010-09-14 |
Theracos, Inc. |
Spiroheterocyclic glycosides and methods of use
|
FR2910892A1
(fr)
|
2006-12-29 |
2008-07-04 |
Genfit Sa |
Derives de 1,3-diphenylpropane substitues, preparations et utilisations.
|
FR2910894A1
(fr)
|
2006-12-29 |
2008-07-04 |
Genfit Sa |
Derives de 3-phenyl-1-(phenylthienyl)propan-1-one et de 3-phenyl-1-(phenylfuranyl)propan-1-one substitues, preparation et utilisation.
|
FR2910893A1
(fr)
|
2006-12-29 |
2008-07-04 |
Genfit Sa |
Derives de (phenylthiazolyl)-phenyl-propan-1-one et de (phenyloxazolyl)-phenyl-propan-1-one substitues, preparations et utilisations.
|
WO2008082017A1
(ja)
|
2007-01-03 |
2008-07-10 |
Takano Co., Ltd. |
環状スルホニウム塩、環状スルホニウム塩の製造方法およびグルコシダーゼ阻害剤
|
AR064736A1
(es)
|
2007-01-04 |
2009-04-22 |
Prosidion Ltd |
Agonistas de gpcr
|
GB0700122D0
(en)
|
2007-01-04 |
2007-02-14 |
Prosidion Ltd |
GPCR agonists
|
PL2114933T3
(pl)
|
2007-01-04 |
2012-02-29 |
Prosidion Ltd |
Piperydyny jako agoniści GPCR
|
BRPI0806312A2
(pt)
|
2007-01-04 |
2011-09-06 |
Prosidion Ltd |
agonistas cgpr piperidina
|
AR064735A1
(es)
|
2007-01-04 |
2009-04-22 |
Prosidion Ltd |
Agonistas de gpcr y composicion farmaceutica en base al compuesto
|
FR2911137B1
(fr)
|
2007-01-05 |
2009-02-20 |
Sanofi Aventis Sa |
Nouveaux derives de 2,4-dianilinopyrimides, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
US20090098130A1
(en)
|
2007-01-05 |
2009-04-16 |
Bradshaw Curt W |
Glucagon-like protein-1 receptor (glp-1r) agonist compounds
|
FR2911138B1
(fr)
|
2007-01-05 |
2009-02-20 |
Sanofi Aventis Sa |
Nouveaux derives de n, n'-2,4-dianilinopyrimidines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
FR2911139A1
(fr)
|
2007-01-05 |
2008-07-11 |
Sanofi Aventis Sa |
Nouveaux derives de phenyl-(4-phenyl-pyrimidin-2-yl)amines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
FR2911140B1
(fr)
|
2007-01-05 |
2009-02-20 |
Sanofi Aventis Sa |
Nouveaux derives de 2-anilino 4-heteroaryle pyrimides, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
JP2008169195A
(ja)
|
2007-01-05 |
2008-07-24 |
Hanmi Pharmaceutical Co Ltd |
キャリア物質を用いたインスリン分泌ペプチド薬物結合体
|
KR100954237B1
(ko)
|
2007-01-08 |
2010-04-21 |
재단법인서울대학교산학협력재단 |
퍼록시솜 증식자 활성화 수용체 델타 리간드 티아졸 화합물및 이를 함유하는 의약, 화장품 및 건강식품 조성물
|
US8138185B2
(en)
|
2007-01-09 |
2012-03-20 |
Novo Nordisk A/S |
Urea glucokinase activators
|
JP4328820B2
(ja)
|
2007-01-10 |
2009-09-09 |
田辺三菱製薬株式会社 |
医薬組成物
|
EP2105435A4
(en)
|
2007-01-10 |
2011-06-15 |
Mitsubishi Tanabe Pharma Corp |
Hydrazone derivatives
|
WO2008084873A1
(ja)
|
2007-01-10 |
2008-07-17 |
Mitsubishi Tanabe Pharma Corporation |
オキシム誘導体
|
JP5226008B2
(ja)
|
2007-01-11 |
2013-07-03 |
ノボ・ノルデイスク・エー/エス |
ウレアグルコキナーゼアクチベーター
|
DE102007002260A1
(de)
|
2007-01-16 |
2008-07-31 |
Sanofi-Aventis |
Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms
|
KR100848491B1
(ko)
|
2007-01-16 |
2008-07-28 |
영진약품공업주식회사 |
베타아미노기를 갖는 2-싸이아졸리딘 유도체, 이의약학적으로 허용 가능한 염 및 이의 제조 방법
|
WO2008087654A2
(en)
|
2007-01-16 |
2008-07-24 |
Cadila Healthcare Limited |
PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1
|
MX2009007669A
(es)
|
2007-01-18 |
2011-12-08 |
Evolva Sa |
1,3,-dioxanos sustituidos y sus usos.
|
US8486994B2
(en)
|
2007-01-18 |
2013-07-16 |
Evolva Sa |
Prodrugs of substituted 1,3-dioxanes and their uses
|
DE102007002717A1
(de)
|
2007-01-18 |
2008-07-24 |
Merck Patent Gmbh |
Heterocyclische Indazolderivate
|
WO2008088006A1
(ja)
|
2007-01-19 |
2008-07-24 |
Shinji Yokoyama |
Ap2抑制剤
|
CN101230058A
(zh)
|
2007-01-23 |
2008-07-30 |
上海恒瑞医药有限公司 |
双环氮杂烷类衍生物、其制备方法及其在医药上的用途
|
CA2676485A1
(en)
|
2007-01-23 |
2008-07-31 |
Reddy Us Therapeutics, Inc. |
Methods and compositions for the treatment of insulin resistance, diabetes, and diabetes-associated dyslipidemia
|
WO2008091863A1
(en)
|
2007-01-23 |
2008-07-31 |
Kalypsys, Inc. |
Sulfonyl-substituted bicyclic compounds as ppar modulators for the treatment of non-alcoholic steatohepatitis
|
WO2008091770A1
(en)
|
2007-01-24 |
2008-07-31 |
Array Biopharma Inc. |
2-aminopyridine derivatives as glucokinase activators
|
TW200843785A
(en)
|
2007-01-26 |
2008-11-16 |
Boehringer Ingelheim Int |
Methods for preventing and treating neurodegenerative disorders
|
JP2010516742A
(ja)
|
2007-01-26 |
2010-05-20 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
神経変性疾患を予防及び治療する方法
|
NZ578296A
(en)
|
2007-01-26 |
2012-07-27 |
Kaneq Pharma Inc |
Fused aromatic ptp-1b inhibitors
|
ATE514692T1
(de)
|
2007-01-26 |
2011-07-15 |
Sanofi Aventis |
Phenothiazin derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
|
EP2128138A1
(en)
|
2007-01-29 |
2009-12-02 |
Takeda Pharmaceutical Company Limited |
Pyrazole compound
|
KR20080071476A
(ko)
|
2007-01-30 |
2008-08-04 |
주식회사 엘지생명과학 |
신규한 디펩티딜 펩티데이즈 iv(dpp-iv) 저해제
|
JP2010518014A
(ja)
|
2007-01-31 |
2010-05-27 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
キナーゼ阻害剤として有用な2−アミノピリジン誘導体
|
WO2008096820A1
(ja)
|
2007-02-07 |
2008-08-14 |
Kyowa Hakko Kirin Co., Ltd. |
ビフェニル誘導体
|
CA2677661A1
(en)
|
2007-02-07 |
2008-08-14 |
Kyowa Hakko Kirin Co., Ltd. |
Tricyclic compounds
|
US8183255B2
(en)
|
2007-02-07 |
2012-05-22 |
Pfizer, Inc. |
N-pyrimidin-4-yl-3-amino-pyrrolo[3,4-c]pyrazole derivatives as PKC kinase inhibitors
|
WO2008096769A1
(ja)
|
2007-02-08 |
2008-08-14 |
Daiichi Sankyo Company, Limited |
置換されたセルコスポラミド誘導体を含有する医薬
|
WO2008097535A2
(en)
|
2007-02-08 |
2008-08-14 |
Merck & Co., Inc. |
Method of treating atherosclerosis, dyslipidemias and related conditions
|
TW200838512A
(en)
|
2007-02-08 |
2008-10-01 |
Daiichi Sankyo Co Ltd |
Crystalline forms of a thiazolidinedione compound and manufacturing methods thereof
|
WO2008099448A1
(ja)
|
2007-02-09 |
2008-08-21 |
Masayoshi Yamaguchi |
糖尿病性疾患の予防・治療剤
|
CA2678265C
(en)
|
2007-02-09 |
2015-10-13 |
Metabasis Therapeutics, Inc. |
Novel antagonists of the glucagon receptor
|
JP2010120851A
(ja)
|
2007-02-09 |
2010-06-03 |
Kyorin Pharmaceut Co Ltd |
二量化シクロ誘導体
|
BRPI0807014A2
(pt)
|
2007-02-09 |
2014-04-22 |
Takeda Pharmaceutical |
Composto, pró-droga, agente farmacêutico, métodos para melhorar a resistência a insulina em um mamífero, método para a profilaxia ou o tratamento de diabetes em um mamífero, e, uso de um composto.
|
TW200836719A
(en)
|
2007-02-12 |
2008-09-16 |
Astrazeneca Ab |
Chemical compounds
|
AU2008216265B2
(en)
|
2007-02-15 |
2014-04-03 |
Indiana University Research And Technology Corporation |
Glucagon/GLP-1 receptor co-agonists
|
DE102007007751A1
(de)
|
2007-02-16 |
2008-08-21 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
JP2010519273A
(ja)
|
2007-02-21 |
2010-06-03 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
四置換グルコピラノシル化ベンゼン誘導体、このような化合物を含む薬物、それらの使用及びそれらの製造方法
|
DE102007008420A1
(de)
|
2007-02-21 |
2008-08-28 |
Merck Patent Gmbh |
Benzimidazolderivate
|
MX2009008923A
(es)
|
2007-02-22 |
2009-08-28 |
Irm Llc |
Compuestos y metodos para modular receptores acoplados por proteina g.
|
BRPI0807637A2
(pt)
|
2007-02-22 |
2014-06-03 |
Irm Llc |
Derivados de tiazol como moduladores de receptores acoplados à proteína g
|
EP1961742A1
(en)
|
2007-02-22 |
2008-08-27 |
Novartis AG |
compounds of formula (I) as serine protease inhibitors
|
US20110003852A1
(en)
|
2007-02-23 |
2011-01-06 |
Soren Ebdrup |
N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
|
EP2129652A2
(en)
|
2007-02-23 |
2009-12-09 |
High Point Pharmaceuticals, LLC |
N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
|
JP2010519240A
(ja)
|
2007-02-23 |
2010-06-03 |
ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー |
11−ベータ−ヒドロキシステロイドデヒドロゲナーゼの阻害剤としての、n−アダマンチルベンズアミド
|
ZA200904916B
(en)
|
2007-02-23 |
2010-09-29 |
High Point Pharmaceuticals Llc |
N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
|
JP5486928B2
(ja)
|
2007-02-26 |
2014-05-07 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
11β−ヒドロキシステロイドデヒドロゲナーゼ1のサイクリックウレアおよびカルバメートインヒビター
|
DE102007009494A1
(de)
|
2007-02-27 |
2008-08-28 |
Bayer Healthcare Ag |
Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung
|
CA2679185A1
(en)
|
2007-02-28 |
2008-09-04 |
Advinus Therapeutics Private Limited |
2,2,2-tri-substituted acetamide derivatives as glucokinase activators, their process and pharmaceutical application
|
WO2008109334A1
(en)
|
2007-03-02 |
2008-09-12 |
Merck & Co., Inc. |
Novel crystalline salt form of an antidiabetic compound
|
US8034819B2
(en)
|
2007-03-07 |
2011-10-11 |
Kyorin Pharmaceutical Co., Ltd. |
Glucokinase activator
|
WO2008108602A1
(en)
|
2007-03-07 |
2008-09-12 |
Dong-A Pharm. Co., Ltd. |
Novel phenylpropionic acid derivatives as peroxisome proliferator-activated gamma receptor modulators, method of the same, and pharmaceutical composition comprising the same
|
KR20090118107A
(ko)
|
2007-03-08 |
2009-11-17 |
아이알엠 엘엘씨 |
Gpr119 활성의 조절제로서의 화합물 및 조성물
|
CN101790512A
(zh)
|
2007-03-08 |
2010-07-28 |
阿尔比里奥公司 |
2-取代-3-苯基丙酸衍生物及其在炎性肠病治疗中的用途
|
AU2008222807A1
(en)
|
2007-03-08 |
2008-09-12 |
Plexxikon, Inc. |
PPAR active compounds
|
PE20090159A1
(es)
|
2007-03-08 |
2009-02-21 |
Plexxikon Inc |
COMPUESTOS DERIVADOS DE ACIDO INDOL-PROPIONICO COMO MODULADORES PPARs
|
CN101260103A
(zh)
|
2007-03-09 |
2008-09-10 |
上海艾力斯医药科技有限公司 |
一类具有部分PPARγ激动剂活性的化合物及其应用
|
MX2009009623A
(es)
|
2007-03-09 |
2009-09-21 |
High Point Pharmaceuticals Llc |
Inidol y bencimidazol amidas como inhibidores de la dehidrogenasa hidroxi-esteroide.
|
WO2008112642A1
(en)
|
2007-03-09 |
2008-09-18 |
Vertex Pharmaceuticals Incorporated |
Aminopyrimidines useful as inhibitors of protein kinases
|
KR20090120510A
(ko)
|
2007-03-09 |
2009-11-24 |
버텍스 파마슈티칼스 인코포레이티드 |
단백질 키나제 억제제로서 유용한 아미노피리미딘
|
WO2008112938A2
(en)
|
2007-03-13 |
2008-09-18 |
New England Medical Center Hospitals, Inc. |
Composition and method for the treatment of diseases affected by a peptide receptor
|
DE102007012645A1
(de)
|
2007-03-16 |
2008-09-18 |
Bayer Healthcare Ag |
Substituierte Imidazo- und Triazolopyrimidine
|
DE102007012284A1
(de)
|
2007-03-16 |
2008-09-18 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
US8173645B2
(en)
|
2007-03-21 |
2012-05-08 |
Takeda San Diego, Inc. |
Glucokinase activators
|
EP1972349A1
(en)
|
2007-03-21 |
2008-09-24 |
Biocompatibles UK Limited |
GLP-1 fusion peptides conjugated to polymer(s), their production and use
|
TW200904454A
(en)
|
2007-03-22 |
2009-02-01 |
Bristol Myers Squibb Co |
Methods for treating obesity employing an SGLT2 inhibitor and compositions thereof
|
TW200904405A
(en)
|
2007-03-22 |
2009-02-01 |
Bristol Myers Squibb Co |
Pharmaceutical formulations containing an SGLT2 inhibitor
|
US8362037B2
(en)
|
2007-03-23 |
2013-01-29 |
Array Biopharma, Inc. |
2-aminopyridine analogs as glucokinase activators
|
US20100105629A1
(en)
|
2007-03-23 |
2010-04-29 |
Bachovchin William W |
N-Substituted Peptidomimetic Inhibitors of Dipeptidylpeptidase IV
|
WO2008116742A1
(en)
|
2007-03-23 |
2008-10-02 |
F. Hoffmann-La Roche Ag |
Aza-pyridopyrimidinone derivatives
|
WO2008116294A1
(en)
|
2007-03-23 |
2008-10-02 |
Matregen Corp. |
Exendin analogs
|
WO2008119005A1
(en)
|
2007-03-27 |
2008-10-02 |
Trustees Of Tufts College |
3,4-dehydro-proline-containing inhibitors of dipeptidylpeptidase iv
|
EP1975176A1
(en)
|
2007-03-27 |
2008-10-01 |
Biocompatibles UK Limited |
Novel glp-1 fusion peptides, their production and use
|
WO2008117982A1
(en)
|
2007-03-28 |
2008-10-02 |
Crystal Genomics, Inc. |
Heterocyclic carboxylic acid derivatives and pharmaceutical composition for inhibiting lipid accumulation containing same
|
US20100056600A1
(en)
|
2007-03-28 |
2010-03-04 |
Soren Ebdrup |
11beta-hsd1 active compounds
|
WO2008119918A1
(en)
|
2007-03-29 |
2008-10-09 |
N.V. Organon |
Mineralocorticoid receptor antagonists
|
JP2010138073A
(ja)
|
2007-03-30 |
2010-06-24 |
Taisho Pharmaceutical Co Ltd |
ピコリン酸アミド化合物
|
CN101274918A
(zh)
|
2007-03-30 |
2008-10-01 |
中国科学院上海药物研究所 |
一类取代五元杂环化合物,其制备方法和医学用途
|
US8133898B2
(en)
|
2007-03-30 |
2012-03-13 |
Takeda Pharmaceutical Company Limited |
Renin inhibitors
|
MX2009010165A
(es)
|
2007-03-30 |
2009-10-12 |
Astrazeneca Ab |
Nuevas imidazo[4,5-b]piridina-7-carboxamidas 704.
|
WO2008121064A1
(en)
|
2007-03-30 |
2008-10-09 |
Astrazeneca Ab |
New imidazo[4,5-b]pyridine-6-halo-7-aryl/heteroaryl compounds 705
|
JPWO2008120655A1
(ja)
|
2007-03-30 |
2010-07-15 |
株式会社医薬分子設計研究所 |
I型11βヒドロキシステロイド脱水素酵素阻害活性を有するオキサゾリジノン誘導体
|
US7838498B2
(en)
|
2007-04-02 |
2010-11-23 |
Theracos, Inc. |
Benzylic glycoside derivatives and methods of use
|
WO2008120813A1
(ja)
|
2007-04-03 |
2008-10-09 |
Mitsubishi Tanabe Pharma Corporation |
ジペプチジルペプチダーゼ4阻害化合物と甘味料との併用
|
CN101279955B
(zh)
|
2007-04-03 |
2012-11-28 |
北京摩力克科技有限公司 |
作为二肽肽激酶-iv抑制剂的n-取代硫吗啉衍生物及其医药用途
|
WO2008126731A1
(ja)
|
2007-04-05 |
2008-10-23 |
Daiichi Sankyo Company, Limited |
アリール誘導体
|
WO2008126732A1
(ja)
|
2007-04-05 |
2008-10-23 |
Daiichi Sankyo Company, Limited |
縮合二環式ヘテロアリール誘導体
|
AU2008235066A1
(en)
|
2007-04-05 |
2008-10-16 |
Sanofi-Aventis |
Imidazolidine carboxamide derivatives as lipase and phospholipase inhibitors
|
CA2682891A1
(en)
|
2007-04-05 |
2008-10-16 |
Sanofi-Aventis |
5-oxoisoxazoles as inhibitors of lipases and phospholipases
|
CA2683653A1
(en)
|
2007-04-10 |
2008-10-16 |
Boehringer Ingelheim International Gmbh |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
WO2008124665A1
(en)
|
2007-04-10 |
2008-10-16 |
Boehringer Ingelheim International Gmbh |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
WO2008127924A1
(en)
|
2007-04-11 |
2008-10-23 |
High Point Pharmaceuticals, Llc. |
Novel compounds
|
EP2146981A1
(en)
|
2007-04-12 |
2010-01-27 |
F. Hoffmann-Roche AG |
Pharmaceutical compounds
|
ATE496045T1
(de)
|
2007-04-12 |
2011-02-15 |
Hoffmann La Roche |
Pyrimidinderivate als inhibitoren von phosphatidylinositol-3-kinase
|
GB0707087D0
(en)
|
2007-04-12 |
2007-05-23 |
Piramed Ltd |
Pharmaceutical compounds
|
WO2008125945A2
(en)
|
2007-04-12 |
2008-10-23 |
Pfizer Inc. |
3-amido-pyrrolo [3, 4-c] pyrazole-5 (1h, 4h, 6h) carbaldehyde derivatives as inhibitors of protein kinase c
|
PE20090695A1
(es)
|
2007-04-13 |
2009-06-27 |
Schering Corp |
Derivados de pirimidindiona como agonistas del receptor de acido nicotinico
|
EP2139843B1
(en)
|
2007-04-16 |
2013-12-25 |
Amgen, Inc |
Substituted biphenyl phenoxy-, thiophenyl- and aminophenylpropanoic acid gpr40 modulators
|
WO2008130951A1
(en)
|
2007-04-17 |
2008-10-30 |
Bristol-Myers Squibb Company |
Fused heterocyclic 11-beta-hydroxysteroid dehydrogenase type i inhibitors
|
CN101679353A
(zh)
|
2007-04-18 |
2010-03-24 |
阿斯利康(瑞典)有限公司 |
制备化合物2-羟基-3-[5-(吗啉-4-基甲基)吡啶-2-基]1h-吲哚-5-腈701的新方法
|
BRPI0810246B1
(pt)
|
2007-04-19 |
2021-11-30 |
Dong-A St Co., Ltd |
Inibidor da dpp-iv incluindo o grupo beta-amino.método de preparação do mesmo e composição famacêutica contendo o mesmo para prevenção e tratamento da dibetes ou obesidade
|
JP2010524941A
(ja)
|
2007-04-20 |
2010-07-22 |
シェーリング コーポレイション |
ピリミジノン誘導体およびそれらの使用方法
|
MX2009011358A
(es)
|
2007-04-20 |
2009-11-05 |
Schering Corp |
Derivados de pirimidinona y metodos para su uso.
|
US20100113330A1
(en)
|
2007-04-20 |
2010-05-06 |
Schering Corporation |
Tetrahydropyrido[4,3-d]pyrimidinone derivatives and methods of use thereof
|
PE20090696A1
(es)
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
JP2010526777A
(ja)
|
2007-04-24 |
2010-08-05 |
ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー |
置換アミドの医薬用途
|
EP2154131A4
(en)
|
2007-04-26 |
2011-09-21 |
Pharmafrontier Co Ltd |
INHIBITOR OF THE G-PROTEIN-COUPLED RECEPTOR AND PHARMACEUTICAL PRODUCT
|
JP2010159210A
(ja)
|
2007-04-26 |
2010-07-22 |
Dainippon Sumitomo Pharma Co Ltd |
縮合複素環誘導体
|
WO2008136394A1
(ja)
|
2007-04-27 |
2008-11-13 |
Ajinomoto Co., Inc. |
ラクタム化合物の製造方法及びその製造中間体
|
US8318746B2
(en)
|
2007-04-27 |
2012-11-27 |
Takeda Pharmaceutical Company Limited |
Nitrogen-containing five-membered heterocyclic compound
|
JP2010526145A
(ja)
|
2007-05-04 |
2010-07-29 |
ブリストル−マイヤーズ スクイブ カンパニー |
[6,6]および[6,7]−二環式gpr119gタンパク質結合受容体アゴニスト
|
CN101668759A
(zh)
|
2007-05-04 |
2010-03-10 |
百时美施贵宝公司 |
[6,5]-双环gpr119g蛋白-偶合受体激动剂
|
JP2010526807A
(ja)
|
2007-05-07 |
2010-08-05 |
メルク・シャープ・エンド・ドーム・コーポレイション |
抗糖尿病活性を有する縮合芳香族化合物を用いた治療法
|
WO2008136642A1
(en)
|
2007-05-07 |
2008-11-13 |
Mazence Inc. |
Naphthoquinone-based pharmaceutical composition for treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases
|
DE102007022565A1
(de)
|
2007-05-14 |
2008-11-20 |
Merck Patent Gmbh |
Heterocyclische Indazolderivate
|
EP1992620A1
(en)
|
2007-05-16 |
2008-11-19 |
Sanofi-Aventis |
Arylamide pyrimidone derivatives for the treatment of neurodegenerative diseases
|
EP1992621A1
(en)
|
2007-05-16 |
2008-11-19 |
Sanofi-Aventis |
Heteroarylamide-substituted pyrimidone derivatives for the treatment of neurodegenerative diseases
|
EP1992624A1
(en)
|
2007-05-16 |
2008-11-19 |
Sanofi-Aventis |
Heteroarylamide pyrimidone compounds
|
EP1992625A1
(en)
|
2007-05-16 |
2008-11-19 |
Sanofi-Aventis |
Arylamide pyrimidone compounds
|
US8236855B2
(en)
|
2007-05-17 |
2012-08-07 |
Case Western Reserve University |
Methods of treating metabolic disorders
|
KR101376432B1
(ko)
|
2007-05-18 |
2014-05-16 |
시오노기세이야쿠가부시키가이샤 |
11β-하이드록시스테로이드 탈수소효소 유형 1 저해 활성을 갖는 질소-함유 헤테로환형 유도체
|
WO2008144346A2
(en)
|
2007-05-18 |
2008-11-27 |
Bristol-Myers Squibb Company |
Crystal structures of sglt2 inhibitors and processes for their preparation
|
WO2008142859A1
(ja)
|
2007-05-18 |
2008-11-27 |
Kowa Company, Ltd. |
新規なスピロオキシインドール化合物及びこれを含有する医薬
|
CN101679317B
(zh)
|
2007-05-29 |
2012-10-31 |
参天制药株式会社 |
具有糖皮质激素受体结合活性且具有导入了磺酸酯或磺酰胺结构的苯基作为取代基的1,2,3,4-四氢喹喔啉衍生物
|
US7829664B2
(en)
|
2007-06-01 |
2010-11-09 |
Boehringer Ingelheim International Gmbh |
Modified nucleotide sequence encoding glucagon-like peptide-1 (GLP-1), nucleic acid construct comprising same for production of glucagon-like peptide-1 (GLP-1), human cells comprising said construct and insulin-producing constructs, and methods of use thereof
|
WO2008145721A2
(en)
|
2007-06-01 |
2008-12-04 |
Novo Nordisk A/S |
N-terminal modification of polypeptides for protection against degradation by aminopeptidases
|
AR066820A1
(es)
|
2007-06-04 |
2009-09-16 |
Novartis Ag |
Compuestos de tiadiazolidin-3 ona
|
US8299115B2
(en)
|
2007-06-08 |
2012-10-30 |
Debnath Bhuniya |
Pyrrole-2-carboxamide derivatives as glucokinase activators, their process and pharmaceutical application
|
EP2164519A2
(en)
|
2007-06-08 |
2010-03-24 |
Ascendis Pharma AS |
Long-acting polymeric prodrugs of exendin
|
US8222285B2
(en)
|
2007-06-11 |
2012-07-17 |
Bristol-Myers Squibb Company |
1,3-dihydroxy substituted phenylamide glucokinase activators
|
DK2158214T3
(da)
|
2007-06-15 |
2011-12-05 |
Zealand Pharma As |
Glukagonanaloger
|
US20110301155A1
(en)
|
2007-06-19 |
2011-12-08 |
Tsuneo Yasuma |
Indazole compounds for activating glucokinase
|
CL2008001839A1
(es)
|
2007-06-21 |
2009-01-16 |
Incyte Holdings Corp |
Compuestos derivados de 2,7-diazaespirociclos, inhibidores de 11-beta hidroxil esteroide deshidrogenasa tipo 1; composicion farmaceutica que comprende a dichos compuestos; utiles para tratar la obesidad, diabetes, intolerancia a la glucosa, diabetes tipo ii, entre otras enfermedades.
|
JPWO2008156174A1
(ja)
|
2007-06-21 |
2010-08-26 |
大正製薬株式会社 |
ピラジンアミド化合物
|
US8222417B2
(en)
|
2007-06-27 |
2012-07-17 |
Taisho Pharmaceutical Co., Ltd |
Compound having 11β-HSD1 inhibitory activity
|
EP2170883A1
(en)
|
2007-06-28 |
2010-04-07 |
Merck Frosst Canada Ltd. |
Substituted fused pyrimidines as antagonists of gpr105 activity
|
WO2009005672A1
(en)
|
2007-06-29 |
2009-01-08 |
Merck & Co., Inc. |
Antidiabetic azaindoles and diazaindoles
|
WO2009003681A1
(en)
|
2007-07-02 |
2009-01-08 |
Santhera Pharmaceuticals (Schweiz) Ag |
Dpp-iv inhibitors
|
EP2500432A3
(en)
|
2007-07-09 |
2012-12-19 |
Imperial Innovations Limited |
Analogues of human pancreatic polypeptide (hPP) and their effects on feeding behaviours
|
DE102007032349A1
(de)
|
2007-07-11 |
2009-01-15 |
Bayer Healthcare Ag |
Imidazo-, Pyrazolopyrazine und Imidazotriazine und ihre Verwendung
|
EP2178821A2
(en)
|
2007-07-12 |
2010-04-28 |
Deviris Inc. |
Hormone sensitive lipase modulators and methods of use
|
WO2009012039A2
(en)
|
2007-07-13 |
2009-01-22 |
Metabasis Therapeutics Inc. |
Crystalline polymorphs
|
ES2423181T3
(es)
|
2007-07-17 |
2013-09-18 |
F. Hoffmann-La Roche Ag |
Inhibidores de la 11ß-hidroxiesteroide-deshidrogenasa
|
AR067568A1
(es)
|
2007-07-17 |
2009-10-14 |
Bristol Myers Squibb Co |
Agonistas de receptor acoplado a proteina g gpr119 de piridona y una composicion farmaceutica que los contiene
|
EP2178868A1
(en)
|
2007-07-18 |
2010-04-28 |
Novartis Ag |
Bicyclic heteroaryl compounds and their use as kinase inhibitors
|
AU2008279447A1
(en)
|
2007-07-19 |
2009-01-29 |
Metabolex, Inc. |
N-azacyclic substituted pyrrole, pyrazole, imidazole, triazole and tetrazole derivatives as agonists of the RUP3 or GPR119 receptor for the treatment of diabetes and metabolic disorders
|
JP5215607B2
(ja)
|
2007-07-23 |
2013-06-19 |
シーシーアイ株式会社 |
ペルオキシゾーム増殖剤応答性受容体(PPAR)αリガンド剤
|
WO2009014676A1
(en)
|
2007-07-23 |
2009-01-29 |
Merck & Co., Inc. |
Novel crystalline form of a dihydrochloride salt of a dipeptidyl peptidase-iv inhibitor
|
US8759355B2
(en)
|
2007-07-25 |
2014-06-24 |
Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. |
Aryl pyrimidine derivatives, preparation methods and pharmaceutical uses thereof
|
US20100317863A1
(en)
|
2007-07-25 |
2010-12-16 |
Boehringer Ingelheim International Gmbh |
Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof
|
WO2009017664A1
(en)
|
2007-07-26 |
2009-02-05 |
Vitae Pharmaceuticals, Inc. |
CYCLIC INHIBITORS OF 11β-HYDROXYSTERIOD DEHYDROGENASE 1
|
CN101808995A
(zh)
|
2007-07-27 |
2010-08-18 |
百时美施贵宝公司 |
新颖的葡糖激酶激活剂及其使用方法
|
DE102007035334A1
(de)
|
2007-07-27 |
2009-01-29 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
DE102007035333A1
(de)
|
2007-07-27 |
2009-01-29 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
US20100267720A1
(en)
|
2007-07-30 |
2010-10-21 |
Astrazeneca Ab |
Crystalline Forms of 2-Hydroxy-3- [5- (Morpholin- 4- Ylmethyl) Pyridin-2-YL] IH- Indole- 5 -Carbonitrile Citrate
|
WO2009019600A2
(en)
|
2007-08-03 |
2009-02-12 |
Dr. Reddy's Laboratories Ltd. |
Modulation of endogenous ampk levels for the treatment of obesity
|
TW200920361A
(en)
|
2007-08-03 |
2009-05-16 |
Betagenon Ab |
Compounds useful as medicaments
|
EP2020232A1
(en)
|
2007-08-03 |
2009-02-04 |
Zeltia, S.A. |
N-(1-thiazolyl)-amide derivatives for the treatment of obesity, diabetes and cardiovascular diseases
|
WO2009020140A1
(ja)
|
2007-08-06 |
2009-02-12 |
Dainippon Sumitomo Pharma Co., Ltd. |
アダマンチルウレア誘導体
|
FR2919869B1
(fr)
|
2007-08-09 |
2009-09-25 |
Sanofi Aventis Sa |
Nouveaux derives de n, n'-2,4-dianilinopyrimidines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
CN106279283A
(zh)
|
2007-08-13 |
2017-01-04 |
症变治疗公司 |
新颖的葡糖激酶活化剂
|
EP2195315B1
(en)
|
2007-08-15 |
2017-01-18 |
Merck Sharp & Dohme Corp. |
Substituted bicyclic piperidinyl-and piperazinyl- sulfonamides useful to inhibit 11 -hydroxysteroid dehydrogenase type-1
|
CN101821271A
(zh)
|
2007-08-15 |
2010-09-01 |
先灵公司 |
可用于抑制1型11β-羟基类固醇脱氢酶的6-取代的磺酰基氮杂双环[3.2.1]辛烷类
|
US20110129542A1
(en)
|
2007-08-15 |
2011-06-02 |
Schering Corporation |
Substituted azepine- and diazepine-sulfonamides useful to inhibit 11beta-hydroxysteroid dehydrogenase type-1
|
WO2009026345A1
(en)
|
2007-08-20 |
2009-02-26 |
Targegen Inc. |
Thiazolidinone compounds, and methods of making and using same
|
CA2696211C
(en)
|
2007-08-21 |
2015-05-26 |
Merck Sharp & Dohme Corp. |
Heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
JP5736098B2
(ja)
|
2007-08-21 |
2015-06-17 |
アッヴィ・インコーポレイテッド |
中枢神経系障害を治療するための医薬組成物
|
RS56822B1
(sr)
|
2007-08-23 |
2018-04-30 |
Theracos Sub Llc |
Derivati (2s,3r,4r,5s,6r)-2-(4-hloro-3-benzilfenil)-6-(hidroksimetil)tetrahidro-2h- piran-3,4,5-triola za upotrebu za lečenje dijabetesa
|
WO2009026658A1
(en)
|
2007-08-29 |
2009-03-05 |
The University Of Sydney |
Ppar agonists
|
WO2009026657A1
(en)
|
2007-08-29 |
2009-03-05 |
The University Of Sydney |
Flavonoid ppar agonists
|
US20090105480A1
(en)
|
2007-08-30 |
2009-04-23 |
Ulrike Bromberger |
Process for the preparation of a dpp-iv inhibitor
|
EP2197858B1
(en)
|
2007-08-31 |
2014-07-02 |
HanAll Biopharma Co., Ltd. |
1,3,5-triazine-2,4,6-triamine compound or pharmaceutical acceptable salt thereof, and pharmaceutical composition comprising the same
|
US20090062369A1
(en)
|
2007-08-31 |
2009-03-05 |
Joaquim Trias |
Use of secretory phospholipase a2 (spla2) inhibitors to decrease spla2 levels
|
DE102007042154A1
(de)
|
2007-09-05 |
2009-03-12 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Arylsulfonylaminomethyphosphonsäure-Derivate, deren Herstellung und deren Verwendung als Arzneimittel
|
WO2009030738A1
(en)
|
2007-09-05 |
2009-03-12 |
Novo Nordisk A/S |
Glucagon-like peptide-1 derivatives and their pharmaceutical use
|
ES2532116T3
(es)
|
2007-09-05 |
2015-03-24 |
Novo Nordisk A/S |
Péptidos derivados con A-B-C-D y sus usos terapéuticos
|
WO2009030774A1
(en)
|
2007-09-05 |
2009-03-12 |
Novo Nordisk A/S |
Truncated glp-1 derivatives and their therapeutical use
|
CA2985271A1
(en)
|
2007-09-06 |
2009-03-12 |
Ohr Pharmaceutical, Inc. |
A method for treating diabetes
|
DE102007042754A1
(de)
|
2007-09-07 |
2009-03-12 |
Bayer Healthcare Ag |
Substituierte 6-Phenylnikotinsäuren und ihre Verwendung
|
EP2650006A1
(en)
|
2007-09-07 |
2013-10-16 |
Ipsen Pharma S.A.S. |
Analogues of exendin-4 and exendin-3
|
JP2010539152A
(ja)
|
2007-09-10 |
2010-12-16 |
プロシディオン・リミテッド |
代謝障害の治療のための化合物
|
MX2010002667A
(es)
|
2007-09-11 |
2010-04-01 |
Activx Biosciences Inc |
Cianoaminoquinolonas y tetrazoloaminoquinolonas como inhibidores de gsk-3.
|
EP2036923A1
(en)
|
2007-09-11 |
2009-03-18 |
Novo Nordisk A/S |
Improved derivates of amylin
|
CN101854948A
(zh)
|
2007-09-11 |
2010-10-06 |
诺沃-诺迪斯克有限公司 |
含有胰岛淀粉样多肽类和长效胰岛素的合剂
|
CN102344457B
(zh)
|
2007-09-12 |
2015-07-22 |
杏林制药株式会社 |
作为 gsk-3 抑制剂的螺环状氨基喹诺酮
|
US7659313B2
(en)
|
2007-09-13 |
2010-02-09 |
Gateway Health Alliances, Inc. |
Methods and related compositions using specific indanes to reduce weight and inhibit lipase, α-amylase and α-glucosidase activity in mammals
|
PL2203433T3
(pl)
|
2007-09-14 |
2013-04-30 |
Metabolic Solutions Dev Co Llc |
5-(4-(2-(3-metoksyfenylo)-2-oksoetoksy)benzylo)tiazolidyno-2,4-dion do stosowania w leczeniu cukrzycy
|
WO2009038204A1
(ja)
|
2007-09-17 |
2009-03-26 |
Pharma Frontier Co., Ltd. |
新規長鎖脂肪酸誘導体化合物及びそれら化合物を有効成分とするgタンパク質共役型レセプター作動剤
|
EP2208728A4
(en)
|
2007-09-19 |
2011-12-21 |
Inst Med Molecular Design Inc |
HETEROCYCLIC DERIVATIVE DERIVATIVE DERIVATIVE TO 11 -? - HYDROXYSTEROIDDEHYDROGENASE TYPE I
|
ES2499018T3
(es)
|
2007-09-20 |
2014-09-26 |
Irm Llc |
Compuestos y composiciones como moduladores de la actividad de GPR119
|
WO2009037719A1
(en)
|
2007-09-21 |
2009-03-26 |
Lupin Limited |
Novel compounds as dipeptidyl peptidase iv (dpp iv) inhibitors
|
PL2209778T3
(pl)
|
2007-09-21 |
2013-02-28 |
Array Biopharma Inc |
Pochodne pirydyn-2-ylo-amino-1,2,4-tiadiazolu jako aktywatory glukokinazy do leczenia cukrzycy
|
ATE513830T1
(de)
|
2007-09-21 |
2011-07-15 |
Sanofi Aventis |
Phenothiazin-derivate mit doppelbindung, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
|
NZ584049A
(en)
|
2007-09-21 |
2011-05-27 |
Sanofi Aventis |
(carboxylalkylene-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament
|
KR20090031122A
(ko)
|
2007-09-21 |
2009-03-25 |
주식회사 중외제약 |
인다졸 골격을 함유하는 화합물, 이의 제조방법 및 상기화합물을 함유하는 약제학적 조성물
|
AU2008303975B2
(en)
|
2007-09-21 |
2013-05-16 |
Sanofi |
(Cyclopropyl-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament
|
US8143280B2
(en)
|
2007-09-27 |
2012-03-27 |
Hoffmann-La Roche Inc. |
Glucocorticoid receptor antagonists
|
AU2008309004A1
(en)
|
2007-09-28 |
2009-04-09 |
Glaxosmithkline Llc |
Glycogen phosphorylase inhibitor compound and pharmaceutical composition thereof
|
CN101932557A
(zh)
|
2007-09-28 |
2010-12-29 |
葛兰素史密丝克莱恩有限责任公司 |
糖原磷酸化酶抑制剂化合物及其药物组合物
|
US8119658B2
(en)
|
2007-10-01 |
2012-02-21 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
CN101827832B
(zh)
|
2007-10-08 |
2014-05-07 |
阿德维纳斯治疗私人有限公司 |
作为葡糖激酶活化剂的乙酰胺衍生物、其制备方法及医药应用
|
DK2195312T3
(da)
|
2007-10-09 |
2013-01-02 |
Merck Patent Gmbh |
Pyridinderivater anvendelige som glucokinaseaktivatorer
|
EP2197849B1
(en)
|
2007-10-09 |
2013-02-27 |
Merck Patent GmbH |
N- ( pyrazole- 3 -yl) -benzamide derivatives as glucokinase activators
|
WO2009047240A1
(en)
|
2007-10-09 |
2009-04-16 |
Smithkline Beecham Corporation |
Indole derivatives useful as ppar activators
|
MX2010003876A
(es)
|
2007-10-10 |
2010-12-02 |
Amgen Inc |
Moduladores de gpr40 bifenilo- sustituidos.
|
DE102007048716A1
(de)
|
2007-10-11 |
2009-04-23 |
Merck Patent Gmbh |
Imidazo[1,2-a]pyrimidinderivate
|
CN101821243B
(zh)
|
2007-10-11 |
2013-05-08 |
中国科学院上海药物研究所 |
一类嘧啶取代苯丙酸衍生物及其作为ppar激动剂的用途
|
WO2009049222A1
(en)
|
2007-10-12 |
2009-04-16 |
Curedm, Inc. |
Compositions and methods of using the human proislet peptide receptor
|
GB0720389D0
(en)
|
2007-10-18 |
2008-11-12 |
Prosidion Ltd |
G-Protein Coupled Receptor Agonists
|
GB0720390D0
(en)
|
2007-10-18 |
2007-11-28 |
Prosidion Ltd |
G-Protein coupled receptor agonists
|
US8907095B2
(en)
|
2007-10-22 |
2014-12-09 |
Merck Sharp & Dohme Corp. |
Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119
|
CN101417999A
(zh)
|
2007-10-25 |
2009-04-29 |
上海恒瑞医药有限公司 |
哌嗪类衍生物,其制备方法及其在医药上的应用
|
ES2386596T3
(es)
|
2007-10-26 |
2012-08-23 |
Japan Tobacco Inc. |
Compuesto espiro-anillo y su uso para fines médicos
|
WO2009056881A1
(en)
|
2007-10-29 |
2009-05-07 |
Astrazeneca Ab |
Chemical compounds 313
|
US8399507B2
(en)
|
2007-10-29 |
2013-03-19 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
MX2010004298A
(es)
|
2007-10-30 |
2010-05-03 |
Univ Indiana Res & Tech Corp |
Compuestos que exhiben actividad antagonista de glucagon y agonista de glp-1.
|
EP2217701B9
(en)
|
2007-10-30 |
2015-02-18 |
Indiana University Research and Technology Corporation |
Glucagon antagonists
|
WO2009057784A1
(ja)
|
2007-11-01 |
2009-05-07 |
Takeda Pharmaceutical Company Limited |
複素環化合物
|
DK2247589T3
(da)
|
2007-11-05 |
2013-01-21 |
Merck Patent Gmbh |
7-azaindolderivater som selektive 11-beta-hydroxysteroid-dehydrogenase type 1-inhibitorer
|
AR069207A1
(es)
|
2007-11-07 |
2010-01-06 |
Vitae Pharmaceuticals Inc |
Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
|
US8710000B2
(en)
|
2007-11-08 |
2014-04-29 |
Novo Nordisk A/S |
Insulin derivative
|
AU2008321959B2
(en)
|
2007-11-12 |
2014-02-13 |
Msd K.K. |
Heteroaryloxy quinazoline derivative
|
EP2058308A1
(fr)
|
2007-11-12 |
2009-05-13 |
Merck Sante |
Dérivés de benzimidazoledihydrothiadiazinone comme inhibiteurs de fructose-1,6-biphosphatase et compositions pharmaceutiques les contenant.
|
US8859580B2
(en)
|
2007-11-16 |
2014-10-14 |
Boehringer Ingelheim International Gmbh |
Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
|
US8119809B2
(en)
|
2007-11-16 |
2012-02-21 |
Rigel Pharmaceuticals, Inc. |
AMPK-activating heterocycloalkyloxy(hetero)aryl carboxamide, sulfonamide and amine compounds and methods for using the same
|
WO2009070314A2
(en)
|
2007-11-26 |
2009-06-04 |
Teva Pharmaceutical Industries Ltd. |
Crystalline form of sitagliptin
|
WO2009069736A1
(ja)
|
2007-11-28 |
2009-06-04 |
Kyowa Hakko Kirin Co., Ltd. |
含窒素化合物
|
WO2009070497A1
(en)
|
2007-11-28 |
2009-06-04 |
Smithkline Beecham Corporation |
SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE
|
MX2010005714A
(es)
|
2007-11-30 |
2010-07-01 |
Hoffmann La Roche |
Compuestos de piridina.
|
PL2247602T3
(pl)
|
2007-11-30 |
2013-08-30 |
Novartis Ag |
Pochodne O-glukuronido-adamantylowe jako inhibitory dipeptydylopeptydazy IV do leczenia cukrzycy
|
US7973051B2
(en)
|
2007-11-30 |
2011-07-05 |
Hoffman-La Roche Inc. |
Aminothiazoles as FBPase inhibitors for diabetes
|
CN101450963B
(zh)
|
2007-11-30 |
2012-03-14 |
中国科学院上海药物研究所 |
葫芦烷型三萜皂苷化合物、其药物组合物及其制备方法和用途
|
WO2009071890A1
(en)
|
2007-12-04 |
2009-06-11 |
Ucb Pharma S.A. |
Tricyclic kinase inhibitors
|
GB0723747D0
(en)
|
2007-12-04 |
2008-12-31 |
Ucb Pharma Sa |
Therapeutic agents
|
WO2009070873A1
(en)
|
2007-12-04 |
2009-06-11 |
Merck Frosst Canada Ltd. |
Substituted 2-naphthoic acids as antagonists of gpr105 activity
|
WO2009071895A1
(en)
|
2007-12-04 |
2009-06-11 |
Ucb Pharma S.A. |
Fused thiazole and thiophene derivatives as kinase inhibitors
|
JP5632612B2
(ja)
|
2007-12-05 |
2014-11-26 |
あすか製薬株式会社 |
ラクタム化合物又はその塩及びppar活性化剤
|
JP5270687B2
(ja)
|
2007-12-11 |
2013-08-21 |
カディラ ヘルスケア リミティド |
グルカゴンアンタゴニスト活性及びglp−1アゴニスト活性を有するペプチド模倣体
|
JP2011032169A
(ja)
|
2007-12-11 |
2011-02-17 |
Genecare Research Institute Co Ltd |
4−アミノピリミジン誘導体および該化合物を含有する医薬組成物
|
EP2229368A1
(en)
|
2007-12-11 |
2010-09-22 |
Vitae Pharmaceuticals, Inc. |
Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
GB0724251D0
(en)
|
2007-12-12 |
2008-02-06 |
Univ Edinburgh |
Therapeutic compounds and their use
|
JP5650540B2
(ja)
|
2007-12-12 |
2015-01-07 |
ライジェル ファーマシューティカルズ, インコーポレイテッド |
代謝障害のためのカルボキサミド、スルホンアミド、およびアミン化合物
|
UA101004C2
(en)
|
2007-12-13 |
2013-02-25 |
Теракос, Инк. |
Derivatives of benzylphenylcyclohexane and use thereof
|
DE102007061756A1
(de)
|
2007-12-20 |
2009-06-25 |
Bayer Healthcare Ag |
Substituierte 4-Aminopyrimidin-5-carbonsäuren und ihre Verwendung
|
WO2009080032A1
(en)
|
2007-12-20 |
2009-07-02 |
Fertin Pharma A/S |
Compressed chewing gum comprising a systemically active small peptide
|
US20100267708A1
(en)
|
2007-12-20 |
2010-10-21 |
Lg Life Sciences Ltd. |
Glucokinase activators and pharmaceutical compositions containing the same as an active ingredient
|
WO2009080024A1
(en)
|
2007-12-20 |
2009-07-02 |
Fertin Pharma A/S |
Compressed chewing gum comprising an incretin mimetic
|
DE102007061757A1
(de)
|
2007-12-20 |
2009-06-25 |
Bayer Healthcare Ag |
Substituierte 2-Phenylpyrimidin-5-carbonsäuren und ihre Verwendung
|
CA2710109C
(en)
|
2007-12-21 |
2016-07-19 |
Lg Life Sciences Ltd. |
Dipeptidyl peptidase-iv inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as active agent
|
IE20070928A1
(en)
|
2007-12-21 |
2009-09-30 |
Giuliani Int Ltd |
Multi target ligands
|
US20100261699A1
(en)
|
2007-12-25 |
2010-10-14 |
Banyu Pharmaceutical Co., Ltd. |
N-pyrazole-2-pyridine carboxamide derivative
|
AU2008340756A1
(en)
|
2007-12-26 |
2009-07-02 |
Sanofi-Aventis |
Cyclic pyridyl-N-(1,3,4)-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals
|
CN101468988A
(zh)
|
2007-12-26 |
2009-07-01 |
上海恒瑞医药有限公司 |
哌嗪类衍生物,其制备方法及其在医药上的应用
|
MX2010007154A
(es)
|
2007-12-27 |
2010-10-05 |
Kissei Pharmaceutical |
Monosebacato de derivado de pirazol.
|
TW200938200A
(en)
|
2007-12-28 |
2009-09-16 |
Dainippon Sumitomo Pharma Co |
Methyl-substituted piperidine derivative
|
WO2009083553A1
(en)
|
2007-12-31 |
2009-07-09 |
Rheoscience A/S |
Azine compounds as glucokinase activators
|
GB0800035D0
(en)
|
2008-01-02 |
2008-02-13 |
Glaxo Group Ltd |
Compounds
|
TW200934490A
(en)
|
2008-01-07 |
2009-08-16 |
Vitae Pharmaceuticals Inc |
Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
|
US20120040897A1
(en)
|
2008-01-10 |
2012-02-16 |
Sun Pharma Advanced Research Company Ltd. |
Novel derivatives of acyl cyanopyrrolidines
|
GB0800383D0
(en)
|
2008-01-10 |
2008-02-20 |
Univ Strathclyde |
Weight reducing compounds
|
CL2009000004A1
(es)
|
2008-01-15 |
2010-02-19 |
Lilly Co Eli |
Forma cristalina de r-2-(4-ciclopropansulfonil-fenil)-n-pirazin-2-il-3-(tetrahidropiran-4-il)-propionamida; composicion farmaceutica que comprende a dicha forma cristalina; y uso para el tratamiento de diabetes o hiperglicemia.
|
CL2008003653A1
(es)
|
2008-01-17 |
2010-03-05 |
Mitsubishi Tanabe Pharma Corp |
Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
|
US20100022590A1
(en)
|
2008-01-17 |
2010-01-28 |
Biovitrum Ab (Publ.) |
Novel compounds
|
US8329707B2
(en)
|
2008-01-18 |
2012-12-11 |
Astellas Pharma Inc. |
Substituted pyrazine compounds
|
US20090238879A1
(en)
|
2008-01-24 |
2009-09-24 |
Northwestern University |
Delivery scaffolds and related methods of use
|
US8592409B2
(en)
|
2008-01-24 |
2013-11-26 |
Vitae Pharmaceuticals, Inc. |
Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
PL2231640T3
(pl)
|
2008-01-24 |
2012-09-28 |
Merck Patent Gmbh |
Pochodne beta-aminokwasowe do leczenia cukrzycy
|
EA018612B1
(ru)
|
2008-01-24 |
2013-09-30 |
Панацеа Биотек Лимитед |
Новые гетероциклические соединения
|
TW200936136A
(en)
|
2008-01-28 |
2009-09-01 |
Sanofi Aventis |
Tetrahydroquinoxaline urea derivatives, their preparation and their therapeutic application
|
EP2090578A1
(en)
|
2008-01-29 |
2009-08-19 |
Sanofi-Aventis |
Substituted arylamide diazepinopyrimidone derivatives for the treatment of neurodegenerative diseases caused by abnormal activity of GSK3-beta
|
EP2085399A1
(en)
|
2008-01-29 |
2009-08-05 |
Sanofi-Aventis |
substituted arylamide oxazepinopyrimidone derivatives
|
EP2090579A1
(en)
|
2008-01-29 |
2009-08-19 |
Sanofi-Aventis |
Substituted heteroarylamide diazepinopyrimidone derivatives
|
EP2085400A1
(en)
|
2008-01-29 |
2009-08-05 |
Sanofi-Aventis |
Substituted heteroarylamide oxazepinopyrimidone derivatives
|
WO2009096503A1
(ja)
|
2008-01-31 |
2009-08-06 |
Daiichi Sankyo Company, Limited |
ベンジルフェニルグルコピラノシド誘導体
|
AU2009211215B2
(en)
|
2008-02-04 |
2011-11-03 |
Astrazeneca Ab |
Novel crystalline forms of 4- [4- (2-adamantylcarbam0yl) -5-tert-butyl-pyrazol-1-yl] benzoic acid
|
CA2714181C
(en)
|
2008-02-04 |
2013-12-24 |
Mercury Therapeutics, Inc. |
Ampk modulators
|
DK2239253T3
(da)
|
2008-02-06 |
2013-09-23 |
Daiichi Sankyo Co Ltd |
Hidtil ukendt phenylpyrrolderivat
|
WO2009099171A1
(ja)
|
2008-02-07 |
2009-08-13 |
Takeda Pharmaceutical Company Limited |
医薬
|
WO2009099172A1
(ja)
|
2008-02-07 |
2009-08-13 |
Takeda Pharmaceutical Company Limited |
医薬
|
EP2252598A2
(en)
|
2008-02-11 |
2010-11-24 |
Vitae Pharmaceuticals, Inc. |
1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
PL384446A1
(pl)
|
2008-02-12 |
2009-08-17 |
Adamed Spółka Z Ograniczoną Odpowiedzialnością |
Sól 5-[[4-[2-(metylo-2-pirydynyloamino)etoksy]fenylo]metylo]-2,4-tiazolidynodionu z kwasem malonowym i sposób jej wytwarzania
|
US8263630B2
(en)
|
2008-02-12 |
2012-09-11 |
Bristol-Myers Squibb Company |
1,2,3-triazoles as 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
US20110028445A1
(en)
|
2008-02-12 |
2011-02-03 |
Boehringer Ingelheim International Gmbh |
Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
|
UY31651A1
(es)
|
2008-02-13 |
2009-09-30 |
|
Nuevos derivados de fluoroglicósidos aromáticos, medicamentos que comprenden estos compuestos y uso de los mismos.
|
JP5730021B2
(ja)
|
2008-02-15 |
2015-06-03 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤としてのシクロアルキルラクタム誘導体
|
JP2011513233A
(ja)
|
2008-02-22 |
2011-04-28 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
Gpr119活性モジュレーターとしての化合物および組成物
|
BRPI0908851A2
(pt)
|
2008-02-22 |
2017-05-30 |
Irm Llc |
compostos e composições como moduladores da atividades de gpr119
|
EA201001332A1
(ru)
|
2008-02-22 |
2011-04-29 |
Айрм Ллк |
Соединения и композиции в качестве модуляторов активности gpr119
|
KR20100124778A
(ko)
|
2008-02-25 |
2010-11-29 |
메르크 파텐트 게엠베하 |
글루코키나제 활성제들
|
KR100864584B1
(ko)
|
2008-02-25 |
2008-10-24 |
성균관대학교산학협력단 |
비오틴으로 수식된 엑센딘 유도체, 이의 제조방법 및 이의용도
|
GB0803494D0
(en)
|
2008-02-26 |
2008-04-02 |
Sterix Ltd |
Compound
|
WO2009106565A1
(en)
|
2008-02-27 |
2009-09-03 |
Biovitrum Ab (Publ) |
Agonists of gpr119
|
US8383629B2
(en)
|
2008-02-27 |
2013-02-26 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of 11β-hydroxysteroid dehydrogenase type 1
|
EA201001367A1
(ru)
|
2008-02-27 |
2011-04-29 |
Мерк Патент Гмбх |
Производные карбоксамид-гетероарила для лечения диабета
|
WO2009106561A1
(en)
|
2008-02-27 |
2009-09-03 |
Biovitrum Ab (Publ) |
Pyrazine compounds for treating gpr119 related disorders
|
FR2928149B1
(fr)
|
2008-02-29 |
2011-01-14 |
Sanofi Aventis |
Composes derives d'azetidines, leur preparation et leur application en therapeutique
|
BRPI0907868A2
(pt)
|
2008-03-01 |
2015-07-21 |
Merck Patent Ges Mit Beschränkter Haftung |
Amidas de ácido 5-oxo-2,3,4,5-tetraidro-benzo[b]oxepina-4-carboxilíco e amidas de ácido 2,3-di-hidro-benzo[b]oxepina-4-carboxilíco para tratamento e prevenção de diabetes tipos 1 e 2
|
WO2009109999A1
(en)
|
2008-03-03 |
2009-09-11 |
Lupin Limited |
Novel protein tyrosine phosphatase - ib inhibitors
|
WO2009109998A1
(en)
|
2008-03-03 |
2009-09-11 |
Lupin Limited |
Novel protein tyrosine phosphatase - ib inhibitors
|
EP2247292B1
(en)
|
2008-03-05 |
2017-04-12 |
Merck Patent GmbH |
Pyridopyrazinones derivatives insulin secretion stimulators, methods for obtaining them and use thereof for the treatment of diabetes
|
CN101945858B
(zh)
|
2008-03-05 |
2014-05-21 |
默克专利有限公司 |
作为胰岛素分泌刺激剂的吡嗪酮类衍生物、获得它们的方法及其在治疗糖尿病中的用途
|
BRPI0912245A2
(pt)
|
2008-03-05 |
2019-09-24 |
Takeda Pharmaceuticals Co |
composto, prodroga, medicamento, métodos de suprimir produção de açúcar em um mamífero e para a profilaxia ou o tratamento de diabetes em um mamífero, e, uso do composto
|
KR101634656B1
(ko)
|
2008-03-05 |
2016-06-29 |
내셔날 헬스 리서치 인스티튜트 |
피롤리딘 유도체
|
EP2260017A1
(en)
|
2008-03-06 |
2010-12-15 |
Amgen, Inc |
Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders
|
BRPI0910282A2
(pt)
|
2008-03-07 |
2015-09-01 |
Transtech Pharma Inc |
Composto oxadiazo-antraceno para o tratamento de diabetes
|
JP2011513483A
(ja)
|
2008-03-10 |
2011-04-28 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
タンパク質キナーゼの阻害剤として有用なピリミジンおよびピリジン
|
KR20100137452A
(ko)
|
2008-03-10 |
2010-12-30 |
다이닛본 스미토모 세이야꾸 가부시끼가이샤 |
비시클릭 피롤 화합물
|
GB0804685D0
(en)
|
2008-03-13 |
2008-04-16 |
Univ Edinburgh |
Therapeutic compounds and their use
|
JP5509104B2
(ja)
|
2008-03-14 |
2014-06-04 |
エグゼリクシス, インコーポレイテッド |
11β−HSD1モジュレータとしてのアザビシクロ[3.2.1]オクチル誘導体
|
WO2009117421A2
(en)
|
2008-03-17 |
2009-09-24 |
Kalypsys, Inc. |
Heterocyclic modulators of gpr119 for treatment of disease
|
US20110105504A1
(en)
|
2008-03-18 |
2011-05-05 |
Vitae Pharmaceuticals ,Inc. |
Inhibitors Of 11beta-Hydroxysteroid Dehydrogenase Type 1
|
FR2928836B1
(fr)
|
2008-03-21 |
2011-08-26 |
Servier Lab |
Forme galenique secable permettant une liberation modifiee du principe actif
|
PE20091674A1
(es)
|
2008-03-27 |
2009-11-04 |
Lilly Co Eli |
Antagonistas del receptor de glucagon
|
US20090247532A1
(en)
|
2008-03-28 |
2009-10-01 |
Mae De Ltd. |
Crystalline polymorph of sitagliptin phosphate and its preparation
|
CN102026636B
(zh)
|
2008-03-31 |
2014-07-16 |
赛马拜制药公司 |
氧亚甲基芳基化合物和其用途
|
WO2009121884A1
(en)
|
2008-04-01 |
2009-10-08 |
Novo Nordisk A/S |
Insulin albumin conjugates
|
FR2929615B1
(fr)
|
2008-04-02 |
2010-12-17 |
Tfchem |
Composes c-aryl glycosides pour le traitement du diabete et de l'obesite.
|
AR071175A1
(es)
|
2008-04-03 |
2010-06-02 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante
|
EP2271619A1
(en)
|
2008-04-07 |
2011-01-12 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
WO2009125434A2
(en)
|
2008-04-07 |
2009-10-15 |
Cadila Healthcare Limited |
Oxime derivatives
|
DE102008017590A1
(de)
|
2008-04-07 |
2009-10-08 |
Merck Patent Gmbh |
Glucopyranosidderivate
|
MX2010011138A
(es)
|
2008-04-10 |
2010-11-12 |
Takeda Pharmaceutical |
Compuestos de anillo fusionados y uso de los mismos.
|
AU2009235784B2
(en)
|
2008-04-11 |
2013-09-19 |
Merck Patent Gmbh |
Thienopyridone derivatives as AMP-activated protein kinase (AMPK) activators
|
WO2009129036A1
(en)
|
2008-04-14 |
2009-10-22 |
Merck & Co., Inc. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
SI2277874T1
(sl)
|
2008-04-15 |
2019-01-31 |
Nippon Chemiphar Co., Ltd. |
Aktivator za peroksisomski proliferator-aktiviran receptor
|
US7741327B2
(en)
|
2008-04-16 |
2010-06-22 |
Hoffmann-La Roche Inc. |
Pyrrolidinone glucokinase activators
|
ES2385185T3
(es)
|
2008-04-16 |
2012-07-19 |
Kissei Pharmaceutical Co., Ltd. |
Hemifumarato de un derivado de pirazol
|
JPWO2009128481A1
(ja)
|
2008-04-16 |
2011-08-04 |
武田薬品工業株式会社 |
含窒素5員複素環化合物
|
US8258134B2
(en)
|
2008-04-16 |
2012-09-04 |
Hoffmann-La Roche Inc. |
Pyridazinone glucokinase activators
|
DE102008019838A1
(de)
|
2008-04-19 |
2009-12-10 |
Boehringer Ingelheim International Gmbh |
Neue Arylsulfonylglycin-Derivate, deren Herstellung und deren Verwendung als Arzneimittel
|
TW200944526A
(en)
|
2008-04-22 |
2009-11-01 |
Vitae Pharmaceuticals Inc |
Carbamate and urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
AU2009239794A1
(en)
|
2008-04-22 |
2009-10-29 |
Astrazeneca Ab |
Substituted pyrimidin-5-carboxamides 281
|
CN101565408A
(zh)
|
2008-04-25 |
2009-10-28 |
国家新药筛选中心 |
一类受体信号转导增效剂,其制备方法和用途
|
PL2275414T3
(pl)
|
2008-04-28 |
2016-01-29 |
Kyorin Seiyaku Kk |
Pochodne cyklopentyloakryloamidu
|
WO2009133099A2
(en)
|
2008-04-28 |
2009-11-05 |
Novo Nordisk A/S |
Insulin precursors for diabetes treatment
|
US8124636B2
(en)
|
2008-04-30 |
2012-02-28 |
Hoffmann-La Roche Inc. |
Imidazolidinone derivatives as 11B-HSD1 inhibitors
|
JP5696037B2
(ja)
|
2008-05-01 |
2015-04-08 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状インヒビター
|
US8138178B2
(en)
|
2008-05-01 |
2012-03-20 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
US8592410B2
(en)
|
2008-05-01 |
2013-11-26 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11BETA-hydroxysteroid dehydrogenase 1
|
CA2723032A1
(en)
|
2008-05-01 |
2009-11-05 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
AU2009243812B2
(en)
|
2008-05-05 |
2014-06-05 |
Merck Patent Gmbh |
NIP thiazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
|
KR20160038065A
(ko)
|
2008-05-05 |
2016-04-06 |
메르크 파텐트 게엠베하 |
Amp-활성화된 단백질 키나아제 (ampk) 활성화제로서의 티에노피리돈 유도체
|
ITMI20080846A1
(it)
|
2008-05-09 |
2009-11-10 |
Andrea Balsari |
Composti a struttura glicosidica attivi nella terapia di stati infiammatori locali e sistemici
|
WO2009139340A1
(ja)
|
2008-05-12 |
2009-11-19 |
武田薬品工業株式会社 |
ピラゾール化合物
|
WO2009138386A2
(en)
|
2008-05-13 |
2009-11-19 |
Boehringer Ingelheim International Gmbh |
Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
|
JP4643760B2
(ja)
|
2008-05-14 |
2011-03-02 |
株式会社三和化学研究所 |
Dpp−iv阻害薬と他の糖尿病治療薬との併用又は組み合せからなる医薬
|
EP2294053B1
(en)
|
2008-05-16 |
2016-01-06 |
Takeda California, Inc. |
Glucokinase activators
|
EP2291358B1
(en)
|
2008-05-16 |
2018-03-28 |
Merck Sharp & Dohme Corp. |
Glucagon receptor antagonists, compositions, and methods for their use
|
US8188098B2
(en)
|
2008-05-19 |
2012-05-29 |
Hoffmann-La Roche Inc. |
GPR119 receptor agonists
|
AU2009249237A1
(en)
|
2008-05-19 |
2009-11-26 |
Schering Corporation |
Bicyclic heterocycle derivatives and use thereof as GPR119 modulators
|
US20090291982A1
(en)
|
2008-05-22 |
2009-11-26 |
Astrazeneca Ab |
New Substituted Oxindole Derivative 352
|
ES2423793T3
(es)
|
2008-05-26 |
2013-09-24 |
Genfit |
Compuestos agonistas de PPAR, preparación y usos para el tratamiento de la diabetes y/o dislipidemias
|
US8263547B2
(en)
|
2008-05-28 |
2012-09-11 |
Massachusetts Institute Of Technology |
DISC-1 pathway activators in the control of neurogenesis
|
AU2009255183A1
(en)
|
2008-06-02 |
2009-12-10 |
Msd K.K. |
Novel isoxazole derivative
|
WO2009147121A1
(en)
|
2008-06-02 |
2009-12-10 |
Smithkline Beecham Corporation |
Carboxyl substituted indoles for use as ppar alpha modulators
|
WO2009149056A2
(en)
|
2008-06-02 |
2009-12-10 |
Dr. Reddy's Laboratories Ltd. |
Combinations of niacin and an oxicam
|
US20110245173A1
(en)
|
2008-06-03 |
2011-10-06 |
Bachovchin William W |
Long-Acting GLP-1 Derivatives, and Methods of Treating Cardiac Dysfunction
|
JOP20190083A1
(ar)
|
2008-06-04 |
2017-06-16 |
Amgen Inc |
بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
|
MX2010013095A
(es)
|
2008-06-06 |
2010-12-21 |
Boehringer Ingelheim Int |
Mimeticos de glucocorticoides, metodos para su fabricacion, composiciones farmaceuticas y usos de los mismos.
|
EP2288605B1
(en)
|
2008-06-09 |
2014-06-25 |
Sanofi |
Annelated pyrrolidin sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
|
US8946212B2
(en)
|
2008-06-09 |
2015-02-03 |
Sanofi-Aventis |
Annelated N-heterocyclic sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
|
WO2010000353A1
(en)
|
2008-06-09 |
2010-01-07 |
Sanofi-Aventis |
Sulfonamides with heterocycle and oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
|
WO2009150144A1
(en)
|
2008-06-10 |
2009-12-17 |
Inovacia Ab |
New gpr119modulators
|
TWI451876B
(zh)
|
2008-06-13 |
2014-09-11 |
Lilly Co Eli |
聚乙二醇化之離脯胰島素化合物
|
PL2285786T3
(pl)
|
2008-06-16 |
2014-01-31 |
Merck Patent Gmbh |
Pochodne chinoksalinodionowe
|
CN102088989B
(zh)
|
2008-06-17 |
2014-11-26 |
印第安纳大学研究及科技有限公司 |
在生理pH缓冲液中具有增强的溶解性和稳定性的胰高血糖素类似物
|
EP2676673B1
(en)
|
2008-06-17 |
2016-11-16 |
Indiana University Research and Technology Corporation |
Glucagon/glp-1 receptor co-agonists
|
AU2009261441B2
(en)
|
2008-06-17 |
2013-01-10 |
Glytech, Inc. |
Oligosaccharide chain added glp-1 peptide
|
WO2010008739A2
(en)
|
2008-06-20 |
2010-01-21 |
Metabolex, Inc. |
Aryl gpr119 agonists and uses thereof
|
KR101273765B1
(ko)
|
2008-06-24 |
2013-06-12 |
아이알엠 엘엘씨 |
G 단백질-커플링된 수용체를 조정하는 화합물 및 방법
|
EP2138498A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
Substituted tricyclic derivatives against neurodegenerative diseases
|
EP2138495A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
Substituted pyrimido[2,1-a]isoquinolin-4-one derivatives
|
EP2138494A1
(en)
|
2008-06-26 |
2009-12-30 |
Sanofi-Aventis |
Substituted alkyl pyrimidin-4-one derivatives
|
EP2138492A1
(en)
|
2008-06-26 |
2009-12-30 |
Sanofi-Aventis |
Substituted pyrimidin-4-one derivatives
|
EP2138493A1
(en)
|
2008-06-26 |
2009-12-30 |
Sanofi-Aventis |
Substituted pyrimidone derivatives
|
EP2138488A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
4-(pyridin-4-yl)-1H-[1,3,5]triazin-2-one derivatives as GSK3-beta inhibitors for the treatment of neurodegenerative diseases
|
EP2138485A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
Substituted N-Oxide pyrazine derivatives
|
GB0812031D0
(en)
|
2008-07-01 |
2008-08-06 |
7Tm Pharma As |
Thiazole derivatives
|
PL2586782T5
(pl)
|
2008-07-03 |
2018-05-30 |
Ratiopharm Gmbh |
Krystaliczne sole sitagliptyny
|
WO2010006214A1
(en)
|
2008-07-09 |
2010-01-14 |
Ambrx, Inc. |
Fgf-21 neutralizing antibodies and their uses
|
GB0812641D0
(en)
|
2008-07-10 |
2008-08-20 |
Prosidion Ltd |
Compounds
|
EP2321308B9
(en)
|
2008-07-10 |
2012-08-08 |
Prosidion Limited |
Piperidine gpcr agonists
|
GB0812648D0
(en)
|
2008-07-10 |
2008-08-20 |
Prosidion Ltd |
Compounds
|
WO2010004343A1
(en)
|
2008-07-10 |
2010-01-14 |
Prosidion Limited |
Piperidinyl gpcr agonists
|
GB0812642D0
(en)
|
2008-07-10 |
2008-08-20 |
Prosidion Ltd |
Compounds
|
GB0812649D0
(en)
|
2008-07-10 |
2008-08-20 |
Prosidion Ltd |
Compounds
|
JP5309216B2
(ja)
|
2008-07-11 |
2013-10-09 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
Gpr119活性のモジュレーターとしての4−フェノキシメチルピペリジン類
|
EP2147910A1
(en)
|
2008-07-15 |
2010-01-27 |
Pronova BioPharma Norge AS |
Novel lipid compounds
|
US8501940B2
(en)
|
2008-07-15 |
2013-08-06 |
Hoffmann-La Roche Inc. |
Tetrahydrocinnoline derivatives
|
MX2011000664A
(es)
|
2008-07-16 |
2011-02-24 |
Schering Corp |
Derivados biciclicos heterociclicos y uso de los mismos como moduladores de gpr119.
|
US8815876B2
(en)
|
2008-07-16 |
2014-08-26 |
Merck Sharp & Dohme Corp. |
Bicyclic heterocycle derivatives and methods of use thereof
|
TW201006821A
(en)
|
2008-07-16 |
2010-02-16 |
Bristol Myers Squibb Co |
Pyridone and pyridazone analogues as GPR119 modulators
|
AU2009270983A1
(en)
|
2008-07-16 |
2010-01-21 |
Schering Corporation |
Bicyclic heterocycle derivatives and their use as GPCR modulators
|
TWI472521B
(zh)
|
2008-07-17 |
2015-02-11 |
Lexicon Pharmaceuticals Inc |
(2s,3r,4r,5s,6r)-2-(4-氯-3-(4-乙氧苄基)苯基)-6-(甲硫)四氫-2h-哌喃-3,4,5-三醇的固體形態與其使用方法
|
US8309597B2
(en)
|
2008-07-25 |
2012-11-13 |
Boehringer Ingelheim International Gmbh |
1,1′-diadamantyl carboxylic acids, medicaments containing such compounds and their use
|
JP5777030B2
(ja)
|
2008-07-25 |
2015-09-09 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤
|
WO2010011917A1
(en)
|
2008-07-25 |
2010-01-28 |
Glaxosmithkline Llc |
SEH AND 11β-HSD1 DUAL INHIBITORS
|
CN102159215B
(zh)
|
2008-07-28 |
2013-07-17 |
爱默蕾大学 |
使用TrkB激动剂治疗各种病症
|
EP2313360B1
(en)
|
2008-07-28 |
2012-09-05 |
Syddansk Universitet |
Compounds for the treatment of metabolic diseases
|
CA2729581A1
(en)
|
2008-07-29 |
2010-02-04 |
Pfizer Inc. |
Fluorinated heteroaryls
|
CA2732280A1
(en)
|
2008-07-30 |
2010-02-04 |
Oncotherapy Science, Inc. |
Benzoimidazole derivatives and glycogen synthase kinase-3 beta inhibitors containing the same
|
EP2320910A4
(en)
|
2008-07-30 |
2012-12-19 |
Glaxosmithkline Llc |
CHEMICAL COMPOUNDS AND ITS USE
|
WO2010014771A1
(en)
|
2008-08-01 |
2010-02-04 |
Ore Pharmaceuticals Inc. |
Romazarit for treating metabolic diseases
|
ATE529402T1
(de)
|
2008-08-01 |
2011-11-15 |
Centre Nat Rech Scient |
3',6-substituierte indirubine und ihre biologischen anwendungen
|
AU2009278929B2
(en)
|
2008-08-04 |
2012-07-05 |
Astrazeneca Ab |
Pyrazolo [3,4] pyrimidin-4-yl derivatives and their uses to treat diabetes and obesity
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
JP2011530506A
(ja)
|
2008-08-07 |
2011-12-22 |
イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ |
グルコース依存性インスリン分泌刺激ポリペプチドの切り詰められたアナログ
|
WO2010016936A1
(en)
|
2008-08-07 |
2010-02-11 |
Ipsen Pharma S.A.S. |
Pharmaceutical compositions of analogues of glucose-dependent insulinotropic polypeptide
|
AU2009280021B2
(en)
|
2008-08-07 |
2012-10-04 |
Ipsen Pharma S.A.S. |
Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal
|
KR101417873B1
(ko)
|
2008-08-07 |
2014-07-09 |
입센 파마 에스.에이.에스 |
포도당 의존적인 인슐린 분비 자극성 폴리펩타이드의 유사체
|
EA020005B1
(ru)
|
2008-08-07 |
2014-07-30 |
Ипсен Фарма С.А.С. |
Аналоги глюкозазависимого инсулинотропного полипептида
|
WO2010018438A2
(en)
|
2008-08-11 |
2010-02-18 |
Hetero Research Foundation |
Tetrazole glycosides
|
WO2010018435A1
(en)
|
2008-08-11 |
2010-02-18 |
Hetero Research Foundation |
Amide glycosides
|
WO2010019828A1
(en)
|
2008-08-13 |
2010-02-18 |
Metabasis Therapeutics, Inc. |
Glucagon receptor antagonists
|
CA2733646A1
(en)
|
2008-08-15 |
2010-02-18 |
Banyu Pharmaceutical Co., Ltd. |
Acetyl pyrrolidinyl indole derivative
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|