ATE471311T1 - Inhibitoren von11-beta- hydroxysteroiddehydrogenase 1 - Google Patents
Inhibitoren von11-beta- hydroxysteroiddehydrogenase 1Info
- Publication number
- ATE471311T1 ATE471311T1 AT07782529T AT07782529T ATE471311T1 AT E471311 T1 ATE471311 T1 AT E471311T1 AT 07782529 T AT07782529 T AT 07782529T AT 07782529 T AT07782529 T AT 07782529T AT E471311 T1 ATE471311 T1 AT E471311T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- inhibitors
- beta
- hydroxysteroid dehydrogenase
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74557406P | 2006-04-25 | 2006-04-25 | |
PCT/US2007/067350 WO2007127763A2 (en) | 2006-04-25 | 2007-04-25 | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE471311T1 true ATE471311T1 (de) | 2010-07-15 |
Family
ID=38541939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07782529T ATE471311T1 (de) | 2006-04-25 | 2007-04-25 | Inhibitoren von11-beta- hydroxysteroiddehydrogenase 1 |
Country Status (14)
Country | Link |
---|---|
US (1) | US7968585B2 (de) |
JP (1) | JP5324427B2 (de) |
CN (1) | CN101432265B (de) |
AT (1) | ATE471311T1 (de) |
AU (1) | AU2007244861B2 (de) |
BR (1) | BRPI0710231A2 (de) |
CA (1) | CA2648019C (de) |
DE (1) | DE602007007211D1 (de) |
DK (1) | DK2035379T3 (de) |
EA (1) | EA015499B1 (de) |
ES (1) | ES2344616T3 (de) |
MX (1) | MX2008013650A (de) |
PT (1) | PT2035379E (de) |
WO (1) | WO2007127763A2 (de) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101426780B (zh) | 2006-04-21 | 2013-06-26 | 伊莱利利公司 | 作为11-β-羟基甾族化合物脱氢酶1的抑制剂的环己基咪唑内酰胺衍生物 |
NZ571175A (en) * | 2006-04-21 | 2011-10-28 | Lilly Co Eli | Cyclohexylpyrazole-lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
MX2008013485A (es) | 2006-04-21 | 2008-10-30 | Lilly Co Eli | Derivados de lactamas de bifenilamida como inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1. |
CN101432262B (zh) | 2006-04-24 | 2011-06-01 | 伊莱利利公司 | 作为11-β-羟类固醇脱氢酶1的抑制剂的环己基取代的吡咯烷酮类 |
EP2029529B1 (de) | 2006-04-24 | 2010-07-07 | Eli Lilly & Company | Substituierte pyrrolidinone als hemmer von 11-beta-hydroxysteroiddehydrogenase 1 |
WO2007127688A2 (en) | 2006-04-24 | 2007-11-08 | Eli Lilly And Company | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
US8148534B2 (en) | 2006-04-25 | 2012-04-03 | Eli Lilly And Company | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
JP5189079B2 (ja) | 2006-04-25 | 2013-04-24 | イーライ リリー アンド カンパニー | 11−β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤 |
CN101448816B (zh) * | 2006-04-28 | 2013-08-07 | 伊莱利利公司 | 作为11-β-羟类固醇脱氢酶1的抑制剂的哌啶基取代的吡咯烷酮类 |
WO2009017664A1 (en) | 2007-07-26 | 2009-02-05 | Vitae Pharmaceuticals, Inc. | CYCLIC INHIBITORS OF 11β-HYDROXYSTERIOD DEHYDROGENASE 1 |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
AR069207A1 (es) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
US8859580B2 (en) | 2007-11-16 | 2014-10-14 | Boehringer Ingelheim International Gmbh | Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
EP2229368A1 (de) | 2007-12-11 | 2010-09-22 | Vitae Pharmaceuticals, Inc. | Cyclische harnstoffe als inhibitoren von 11beta-hydroxysteroiddehydrogenase 1 |
TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
US8592409B2 (en) | 2008-01-24 | 2013-11-26 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
JP5730021B2 (ja) | 2008-02-15 | 2015-06-03 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤としてのシクロアルキルラクタム誘導体 |
US8592410B2 (en) | 2008-05-01 | 2013-11-26 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11BETA-hydroxysteroid dehydrogenase 1 |
US8138178B2 (en) | 2008-05-01 | 2012-03-20 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
JP5696037B2 (ja) | 2008-05-01 | 2015-04-08 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状インヒビター |
WO2009138386A2 (en) | 2008-05-13 | 2009-11-19 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
JP5777030B2 (ja) | 2008-07-25 | 2015-09-09 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤 |
EP2324018B1 (de) | 2008-07-25 | 2013-09-04 | Boehringer Ingelheim International GmbH | Cyclische inhibitoren von 11-beta-hydroxysteroiddehydrogenase 1 |
WO2010010150A1 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 |
US8637505B2 (en) | 2009-02-04 | 2014-01-28 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
EP2243479A3 (de) | 2009-04-20 | 2011-01-19 | Abbott Laboratories | Neuartige Amid- und Amidinderivate und deren Verwendungen |
UA109255C2 (ru) | 2009-04-30 | 2015-08-10 | Берінгер Інгельхайм Інтернешнл Гмбх | Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1 |
JP5656986B2 (ja) | 2009-06-11 | 2015-01-21 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 1,3−オキサジナン−2−オン構造に基づく11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状阻害剤 |
US8440710B2 (en) | 2009-10-15 | 2013-05-14 | Hoffmann-La Roche Inc. | HSL inhibitors useful in the treatment of diabetes |
TW201118069A (en) * | 2009-10-28 | 2011-06-01 | Lundbeck & Co As H | Spirolactam derivatives and uses of same |
EP2496589B1 (de) | 2009-11-05 | 2014-03-05 | Boehringer Ingelheim International GmbH | Neue chirale phosphorliganden |
TWI531571B (zh) | 2009-11-06 | 2016-05-01 | 維它藥物公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜芳基羰基衍生物 |
WO2011068927A2 (en) * | 2009-12-04 | 2011-06-09 | Abbott Laboratories | 11-β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 (11B-HSD1) INHIBITORS AND USES THEREOF |
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP2576570A1 (de) | 2010-05-26 | 2013-04-10 | Boehringer Ingelheim International GmbH | 2-oxo-1,2-dihydropyridin-4-ylborsäure-derivate |
US8933072B2 (en) | 2010-06-16 | 2015-01-13 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
WO2011157827A1 (de) | 2010-06-18 | 2011-12-22 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
EP2585444B1 (de) * | 2010-06-25 | 2014-10-22 | Boehringer Ingelheim International GmbH | Azaspirohexanone als 11-beta-hsd1-hemmer zur behandlung von stoffwechselerkrankungen |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
WO2012059416A1 (en) | 2010-11-02 | 2012-05-10 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations for the treatment of metabolic disorders |
TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物 |
WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
WO2012120053A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
US8722721B2 (en) | 2011-03-16 | 2014-05-13 | Hoffmann-La Roche Inc. | SEC-hydroxycyclohexyl derivatives |
US8703807B2 (en) * | 2011-03-17 | 2014-04-22 | Hoffmann-La Roche Inc. | Azaspirodecanone compounds |
US8809384B2 (en) * | 2011-03-25 | 2014-08-19 | Hoffmann-La Roche Inc. | Azaspirodecanone compounds |
US8501768B2 (en) * | 2011-05-17 | 2013-08-06 | Hoffmann-La Roche Inc. | Hexahydrocyclopentapyrrolone, hexahydropyrrolopyrrolone, octahydropyrrolopyridinone and octahydropyridinone compounds |
EP2554539B1 (de) | 2011-08-02 | 2014-12-10 | Universität Potsdam | Verfahren zur Herstellung von gamma-Spirolactamen aus zyklischen ungesättigten Carbonsäuren |
WO2013025664A1 (en) | 2011-08-17 | 2013-02-21 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
BR112017000762A2 (pt) | 2014-07-15 | 2017-11-21 | Gruenenthal Gmbh | derivados de azaspiro(4.5)decano substituído. |
TW201607923A (zh) | 2014-07-15 | 2016-03-01 | 歌林達有限公司 | 被取代之氮螺環(4.5)癸烷衍生物 |
WO2019099760A1 (en) | 2017-11-16 | 2019-05-23 | University Of Houston System | Aryl-substituted acetamide and pyrrolidin-2-one derivatives and their use for the treatment of seizures |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004056744A1 (en) | 2002-12-23 | 2004-07-08 | Janssen Pharmaceutica N.V. | Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors |
US7687644B2 (en) | 2004-05-07 | 2010-03-30 | Janssen Pharmaceutica Nv | Adamantyl pyrrolidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
NZ551077A (en) * | 2004-05-07 | 2009-05-31 | Janssen Pharmaceutica Nv | Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
WO2006040329A1 (en) * | 2004-10-12 | 2006-04-20 | Novo Nordisk A/S | 1 ibeta- hydroxysteroid dehydrogenase type 1 active spiro compounds |
EP1807072B1 (de) * | 2004-10-29 | 2009-01-07 | Eli Lilly And Company | Cycloalkyl-lactam-derivate als inhibitoren von 11-beta-hydroxysteroiddehydrogenase 1 |
SG161261A1 (en) | 2004-11-10 | 2010-05-27 | Incyte Corp | Lactam compounds and their use as pharmaceuticals |
ES2308602T3 (es) | 2004-12-20 | 2008-12-01 | Eli Lilly And Company | Derivados de cicloalquil lactamas como inhibidores de la 11-beta-hidroxiesteroide deshidrogenasa 1. |
DE602005008282D1 (de) | 2004-12-21 | 2008-08-28 | Lilly Co Eli | Cycloalkyl-lactam-derivate als inhibitoren von 11-beta-hydroxysteroiddehydrogenase 1 |
JPWO2006104280A1 (ja) | 2005-03-31 | 2008-09-11 | 武田薬品工業株式会社 | 糖尿病の予防・治療剤 |
WO2007084314A2 (en) | 2006-01-12 | 2007-07-26 | Incyte Corporation | MODULATORS OF 11-ß HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME |
NZ571175A (en) | 2006-04-21 | 2011-10-28 | Lilly Co Eli | Cyclohexylpyrazole-lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
MX2008013485A (es) | 2006-04-21 | 2008-10-30 | Lilly Co Eli | Derivados de lactamas de bifenilamida como inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1. |
CN101426780B (zh) | 2006-04-21 | 2013-06-26 | 伊莱利利公司 | 作为11-β-羟基甾族化合物脱氢酶1的抑制剂的环己基咪唑内酰胺衍生物 |
CN101432262B (zh) | 2006-04-24 | 2011-06-01 | 伊莱利利公司 | 作为11-β-羟类固醇脱氢酶1的抑制剂的环己基取代的吡咯烷酮类 |
EP2029529B1 (de) | 2006-04-24 | 2010-07-07 | Eli Lilly & Company | Substituierte pyrrolidinone als hemmer von 11-beta-hydroxysteroiddehydrogenase 1 |
WO2007127688A2 (en) | 2006-04-24 | 2007-11-08 | Eli Lilly And Company | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
JP5189079B2 (ja) | 2006-04-25 | 2013-04-24 | イーライ リリー アンド カンパニー | 11−β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤 |
US8148534B2 (en) | 2006-04-25 | 2012-04-03 | Eli Lilly And Company | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
CN101448816B (zh) | 2006-04-28 | 2013-08-07 | 伊莱利利公司 | 作为11-β-羟类固醇脱氢酶1的抑制剂的哌啶基取代的吡咯烷酮类 |
CL2008001839A1 (es) | 2007-06-21 | 2009-01-16 | Incyte Holdings Corp | Compuestos derivados de 2,7-diazaespirociclos, inhibidores de 11-beta hidroxil esteroide deshidrogenasa tipo 1; composicion farmaceutica que comprende a dichos compuestos; utiles para tratar la obesidad, diabetes, intolerancia a la glucosa, diabetes tipo ii, entre otras enfermedades. |
-
2007
- 2007-04-25 AT AT07782529T patent/ATE471311T1/de active
- 2007-04-25 JP JP2009507936A patent/JP5324427B2/ja not_active Expired - Fee Related
- 2007-04-25 MX MX2008013650A patent/MX2008013650A/es active IP Right Grant
- 2007-04-25 EA EA200870475A patent/EA015499B1/ru not_active IP Right Cessation
- 2007-04-25 AU AU2007244861A patent/AU2007244861B2/en not_active Ceased
- 2007-04-25 ES ES07782529T patent/ES2344616T3/es active Active
- 2007-04-25 CN CN2007800148399A patent/CN101432265B/zh not_active Expired - Fee Related
- 2007-04-25 BR BRPI0710231-3A patent/BRPI0710231A2/pt not_active IP Right Cessation
- 2007-04-25 DK DK07782529.7T patent/DK2035379T3/da active
- 2007-04-25 US US12/297,906 patent/US7968585B2/en not_active Expired - Fee Related
- 2007-04-25 PT PT07782529T patent/PT2035379E/pt unknown
- 2007-04-25 CA CA2648019A patent/CA2648019C/en not_active Expired - Fee Related
- 2007-04-25 WO PCT/US2007/067350 patent/WO2007127763A2/en active Application Filing
- 2007-04-25 DE DE602007007211T patent/DE602007007211D1/de active Active
Also Published As
Publication number | Publication date |
---|---|
JP2009535357A (ja) | 2009-10-01 |
EA200870475A1 (ru) | 2009-06-30 |
WO2007127763A3 (en) | 2007-12-13 |
EA015499B1 (ru) | 2011-08-30 |
DE602007007211D1 (de) | 2010-07-29 |
MX2008013650A (es) | 2008-11-04 |
WO2007127763A2 (en) | 2007-11-08 |
CA2648019C (en) | 2014-04-01 |
CA2648019A1 (en) | 2007-11-08 |
ES2344616T3 (es) | 2010-09-01 |
JP5324427B2 (ja) | 2013-10-23 |
AU2007244861A1 (en) | 2007-11-08 |
DK2035379T3 (da) | 2010-09-06 |
US20090099180A1 (en) | 2009-04-16 |
US7968585B2 (en) | 2011-06-28 |
CN101432265B (zh) | 2011-12-14 |
PT2035379E (pt) | 2010-07-13 |
BRPI0710231A2 (pt) | 2011-08-02 |
CN101432265A (zh) | 2009-05-13 |
AU2007244861B2 (en) | 2012-03-15 |
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