IL164249A0 - Acyl-3-carboxphenylurea derivatives, processes forpreparing them and their use - Google Patents
Acyl-3-carboxphenylurea derivatives, processes forpreparing them and their useInfo
- Publication number
- IL164249A0 IL164249A0 IL16424902A IL16424902A IL164249A0 IL 164249 A0 IL164249 A0 IL 164249A0 IL 16424902 A IL16424902 A IL 16424902A IL 16424902 A IL16424902 A IL 16424902A IL 164249 A0 IL164249 A0 IL 164249A0
- Authority
- IL
- Israel
- Prior art keywords
- carboxphenylurea
- forpreparing
- acyl
- derivatives
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
- C07C275/48—Y being a hydrogen or a carbon atom
- C07C275/54—Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10215907A DE10215907A1 (en) | 2002-04-11 | 2002-04-11 | Acyl-4-carboxyphenyl-urea derivatives, processes for their preparation and their use |
PCT/EP2003/003251 WO2003084922A1 (en) | 2002-04-11 | 2003-03-28 | Acyl-4-carboxyphenylurea derivatives, method for production and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IL164249A0 true IL164249A0 (en) | 2005-12-18 |
Family
ID=28684935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16424902A IL164249A0 (en) | 2002-04-11 | 2002-04-11 | Acyl-3-carboxphenylurea derivatives, processes forpreparing them and their use |
Country Status (28)
Country | Link |
---|---|
EP (1) | EP1497262B1 (en) |
JP (1) | JP4328211B2 (en) |
KR (1) | KR20040097333A (en) |
CN (1) | CN1286805C (en) |
AR (1) | AR039403A1 (en) |
AT (1) | ATE476412T1 (en) |
AU (1) | AU2003216900A1 (en) |
BR (1) | BR0309242A (en) |
CA (1) | CA2481817A1 (en) |
DE (2) | DE10215907A1 (en) |
EC (1) | ECSP045347A (en) |
HR (1) | HRPK20040930B3 (en) |
HU (1) | HUP0500440A2 (en) |
IL (1) | IL164249A0 (en) |
MA (1) | MA26390A1 (en) |
MX (1) | MXPA04009468A (en) |
NO (1) | NO20044882L (en) |
NZ (1) | NZ535834A (en) |
OA (1) | OA12805A (en) |
PA (1) | PA8570901A1 (en) |
PE (1) | PE20040374A1 (en) |
PL (1) | PL371279A1 (en) |
RU (1) | RU2004133045A (en) |
TN (1) | TNSN04199A1 (en) |
TW (1) | TW200404762A (en) |
UA (1) | UA78040C2 (en) |
UY (1) | UY27761A1 (en) |
WO (1) | WO2003084922A1 (en) |
Families Citing this family (43)
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DE10306502B4 (en) * | 2003-02-17 | 2005-03-17 | Aventis Pharma Deutschland Gmbh | Substituted 3- (benzoylureido) thiophene derivatives and medicaments containing them |
DE10308352A1 (en) | 2003-02-27 | 2004-09-09 | Aventis Pharma Deutschland Gmbh | Branched side chain arylcycloalkyl derivatives, process for their preparation and their use as medicaments |
DE10308351A1 (en) | 2003-02-27 | 2004-11-25 | Aventis Pharma Deutschland Gmbh | 1,3-substituted cycloalkyl derivatives having acidic, usually heterocyclic groups, processes for their preparation and their use as medicaments |
DE10308353A1 (en) | 2003-02-27 | 2004-12-02 | Aventis Pharma Deutschland Gmbh | Diarylcycloalkyl derivatives, processes for their preparation and their use as medicines |
US7148246B2 (en) | 2003-02-27 | 2006-12-12 | Sanofi-Aventis Deutschland Gmbh | Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals |
DE10308355A1 (en) | 2003-02-27 | 2004-12-23 | Aventis Pharma Deutschland Gmbh | Aryl-cycloalkyl-substituted alkanoic acid derivatives, process for their preparation and their use as medicaments |
DE10309929B4 (en) * | 2003-03-07 | 2006-02-23 | Sanofi-Aventis Deutschland Gmbh | Substituted benzoylureidopyridyl-piperidine and -pyrrolidine-carboxylic acid derivatives, process for their preparation and their use |
US7501440B2 (en) | 2003-03-07 | 2009-03-10 | Sanofi-Aventis Deutschland Gmbh | Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use |
US7241787B2 (en) | 2004-01-25 | 2007-07-10 | Sanofi-Aventis Deutschland Gmbh | Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments |
EP1586573B1 (en) | 2004-04-01 | 2007-02-07 | Sanofi-Aventis Deutschland GmbH | Oxadiazolones, processes for their preparation and their use as pharmaceuticals |
DE102005026762A1 (en) | 2005-06-09 | 2006-12-21 | Sanofi-Aventis Deutschland Gmbh | Azolopyridin-2-one derivatives as inhibitors of lipases and phospholipases |
EP1931337B1 (en) | 2005-09-29 | 2013-10-23 | Sanofi | Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals |
PE20080251A1 (en) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | USES OF DPP IV INHIBITORS |
RU2009108280A (en) | 2006-08-08 | 2010-09-20 | Санофи-Авентис (Fr) | Arylamino-arylalkyl-substituted imidazolidine-2,4-dione, methods for their preparation containing these compounds and their use |
DE102007005045B4 (en) | 2007-01-26 | 2008-12-18 | Sanofi-Aventis | Phenothiazine derivatives, process for their preparation and their use as medicines |
DE102007012284A1 (en) | 2007-03-16 | 2008-09-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Novel substituted arylsulfonylglycines, their preparation and their use as pharmaceuticals |
DE102007035333A1 (en) | 2007-07-27 | 2009-01-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Novel substituted arylsulfonylglycines, their preparation and their use as pharmaceuticals |
DE102007035334A1 (en) | 2007-07-27 | 2009-01-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Novel substituted arylsulfonylglycines, their preparation and their use as pharmaceuticals |
EP2025674A1 (en) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituted tetra hydro naphthalines, method for their manufacture and their use as drugs |
DE102007042154A1 (en) | 2007-09-05 | 2009-03-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Arylsulfonylaminomethyphosphonsäure derivatives, their preparation and their use as medicaments |
DE102007054497B3 (en) | 2007-11-13 | 2009-07-23 | Sanofi-Aventis Deutschland Gmbh | New crystalline hydrate form of dodecanedioic acid 4-((2S,3R)-3-((S)-3-(4-fluoro-phenyl)-3-hydroxy-propyl)-2-(4-methoxy-phenyl)-4-oxo-azetidin-1-yl)-benzylamide ((2S,3R,4R,5R)-pentahydroxy-hexyl)-amide useful e.g. to treat hyperlipidemia |
WO2010003624A2 (en) | 2008-07-09 | 2010-01-14 | Sanofi-Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
WO2011023754A1 (en) | 2009-08-26 | 2011-03-03 | Sanofi-Aventis | Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use |
WO2011107494A1 (en) | 2010-03-03 | 2011-09-09 | Sanofi | Novel aromatic glycoside derivatives, medicaments containing said compounds, and the use thereof |
EP2582709B1 (en) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
EP2683702B1 (en) | 2011-03-08 | 2014-12-24 | Sanofi | New substituted phenyl oxathiazine derivatives, method for their manufacture, medicines containing these compounds and their application |
EP2683704B1 (en) | 2011-03-08 | 2014-12-17 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2683699B1 (en) | 2011-03-08 | 2015-06-24 | Sanofi | Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
US8895547B2 (en) | 2011-03-08 | 2014-11-25 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
WO2012120054A1 (en) | 2011-03-08 | 2012-09-13 | Sanofi | Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
WO2012120051A1 (en) | 2011-03-08 | 2012-09-13 | Sanofi | Benzyl-oxathiazine derivates substituted with adamantane or noradamantane, medicaments containing said compounds and use thereof |
US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
EP2683701B1 (en) | 2011-03-08 | 2014-12-24 | Sanofi | Oxathiazine derivatives substituted with benzyl or heteromethylene groups, method for their preparation, their usage as medicament, medicament containing same and its use |
US8901114B2 (en) | 2011-03-08 | 2014-12-02 | Sanofi | Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof |
EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
JP6358942B2 (en) * | 2014-12-05 | 2018-07-18 | 沢井製薬株式会社 | Reagent for measuring endotoxin and method for measuring endotoxin |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2843851A1 (en) * | 1978-10-07 | 1980-04-17 | Bayer Ag | SUBSTITUTED N-BENZOYL-N'-TERT.-ALKOXYCARBONYLPHENYL- (THIO) UREAS, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS INSECTICIDES |
DE3100911A1 (en) * | 1981-01-14 | 1982-08-05 | Basf Ag, 6700 Ludwigshafen | N-BENZOYL-N'-PHENYL UREAS AND THEIR USE FOR CONTROLLING INSECTS |
DE3217619A1 (en) * | 1982-05-11 | 1983-11-17 | Bayer Ag, 5090 Leverkusen | 2,4-DIHALOGENBENZOYL (THIO) UREA, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A PEST CONTROL |
DE3217620A1 (en) * | 1982-05-11 | 1983-11-17 | Bayer Ag, 5090 Leverkusen | 2,5-DIHALOGENBENZOYL (THIO) UREA, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A PEST CONTROL |
EP0136745B1 (en) * | 1983-09-01 | 1989-06-07 | Duphar International Research B.V | Benzoyl urea derivatives having anti-tumor activity |
EP0167197B1 (en) * | 1984-07-05 | 1989-01-18 | Duphar International Research B.V | Benzoylurea compounds, and insecticidal and acaricidal compositions comprising same |
AU601145B2 (en) * | 1985-03-01 | 1990-09-06 | Duphar International Research B.V. | Benzoyl urea derivatives having anti-tumor activity |
DE3722155A1 (en) * | 1987-07-04 | 1989-01-12 | Basf Ag | (N-BENZOYL-N'-HALOGENALKOXYCARBONYLPHENYL) UREAS |
DK0832066T3 (en) * | 1995-06-06 | 2001-11-19 | Pfizer | Substituted N- (indole-2-carbonyl) amides and derivatives as glycogen phosphorylase inhibitors |
UY26615A1 (en) * | 2000-03-16 | 2001-10-25 | Pfizer Prod Inc | GLUCOGEN PHOSPHORYLASE INHIBITOR. |
DE50102147D1 (en) * | 2000-06-09 | 2004-06-03 | Aventis Pharma Gmbh | ACYLPHENYL URINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT |
GB0021831D0 (en) * | 2000-09-06 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
TWI236474B (en) * | 2001-04-03 | 2005-07-21 | Telik Inc | Antagonists of MCP-1 function and methods of use thereof |
PE20021091A1 (en) * | 2001-05-25 | 2003-02-04 | Aventis Pharma Gmbh | DERIVATIVES OF PHENYLUREA SUBSTITUTED WITH CARBONAMIDE AND PROCEDURE FOR THEIR PREPARATION |
DE10215908B4 (en) * | 2002-04-11 | 2005-08-18 | Aventis Pharma Deutschland Gmbh | Acyl-3-carboxyphenyl-urea derivatives and their use as medicaments |
-
2002
- 2002-04-11 IL IL16424902A patent/IL164249A0/en unknown
- 2002-04-11 DE DE10215907A patent/DE10215907A1/en not_active Withdrawn
-
2003
- 2003-03-28 UA UA20041109224A patent/UA78040C2/en unknown
- 2003-03-28 CN CNB038081873A patent/CN1286805C/en not_active Expired - Fee Related
- 2003-03-28 EP EP03712111A patent/EP1497262B1/en not_active Expired - Lifetime
- 2003-03-28 CA CA002481817A patent/CA2481817A1/en not_active Abandoned
- 2003-03-28 JP JP2003582121A patent/JP4328211B2/en not_active Expired - Fee Related
- 2003-03-28 NZ NZ535834A patent/NZ535834A/en unknown
- 2003-03-28 BR BR0309242-9A patent/BR0309242A/en not_active IP Right Cessation
- 2003-03-28 WO PCT/EP2003/003251 patent/WO2003084922A1/en active Application Filing
- 2003-03-28 OA OA1200400276A patent/OA12805A/en unknown
- 2003-03-28 DE DE50312949T patent/DE50312949D1/en not_active Expired - Lifetime
- 2003-03-28 PL PL03371279A patent/PL371279A1/en not_active Application Discontinuation
- 2003-03-28 AU AU2003216900A patent/AU2003216900A1/en not_active Abandoned
- 2003-03-28 AT AT03712111T patent/ATE476412T1/en active
- 2003-03-28 MX MXPA04009468A patent/MXPA04009468A/en unknown
- 2003-03-28 KR KR10-2004-7016158A patent/KR20040097333A/en not_active Application Discontinuation
- 2003-03-28 HU HU0500440A patent/HUP0500440A2/en unknown
- 2003-03-28 RU RU2004133045/04A patent/RU2004133045A/en not_active Application Discontinuation
- 2003-04-07 PE PE2003000349A patent/PE20040374A1/en not_active Application Discontinuation
- 2003-04-09 TW TW092108057A patent/TW200404762A/en unknown
- 2003-04-09 AR ARP030101247A patent/AR039403A1/en unknown
- 2003-04-09 PA PA20038570901A patent/PA8570901A1/en unknown
- 2003-04-11 UY UY27761A patent/UY27761A1/en unknown
-
2004
- 2004-09-20 MA MA27867A patent/MA26390A1/en unknown
- 2004-10-07 HR HR20040930A patent/HRPK20040930B3/en not_active IP Right Cessation
- 2004-10-08 TN TNP2004000199A patent/TNSN04199A1/en unknown
- 2004-10-08 EC EC2004005347A patent/ECSP045347A/en unknown
- 2004-11-09 NO NO20044882A patent/NO20044882L/en unknown
Also Published As
Publication number | Publication date |
---|---|
HRP20040930A2 (en) | 2005-04-30 |
MXPA04009468A (en) | 2005-01-25 |
TNSN04199A1 (en) | 2007-03-12 |
NZ535834A (en) | 2006-07-28 |
MA26390A1 (en) | 2004-11-01 |
PL371279A1 (en) | 2005-06-13 |
HUP0500440A2 (en) | 2005-08-29 |
WO2003084922A8 (en) | 2005-01-13 |
PE20040374A1 (en) | 2004-07-20 |
AU2003216900A1 (en) | 2003-10-20 |
NO20044882L (en) | 2004-11-09 |
TW200404762A (en) | 2004-04-01 |
JP2005522480A (en) | 2005-07-28 |
BR0309242A (en) | 2005-02-09 |
UA78040C2 (en) | 2007-02-15 |
EP1497262A1 (en) | 2005-01-19 |
JP4328211B2 (en) | 2009-09-09 |
EP1497262B1 (en) | 2010-08-04 |
HRPK20040930B3 (en) | 2006-09-30 |
OA12805A (en) | 2006-07-11 |
CN1646485A (en) | 2005-07-27 |
ATE476412T1 (en) | 2010-08-15 |
DE10215907A1 (en) | 2003-11-06 |
RU2004133045A (en) | 2005-05-27 |
UY27761A1 (en) | 2003-10-31 |
DE50312949D1 (en) | 2010-09-16 |
ECSP045347A (en) | 2004-11-26 |
AR039403A1 (en) | 2005-02-16 |
CA2481817A1 (en) | 2003-10-16 |
KR20040097333A (en) | 2004-11-17 |
PA8570901A1 (en) | 2003-11-12 |
CN1286805C (en) | 2006-11-29 |
WO2003084922A1 (en) | 2003-10-16 |
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