BR0312957A - Composto ou um sal farmaceuticamente aceitável deste, uso do mesmo, composição farmacêutica, e, método para produzir um efeito inibidor de 11betahsd1 em um animal de sangue quente, tal como o homem, em necessidade de tal tratamento - Google Patents
Composto ou um sal farmaceuticamente aceitável deste, uso do mesmo, composição farmacêutica, e, método para produzir um efeito inibidor de 11betahsd1 em um animal de sangue quente, tal como o homem, em necessidade de tal tratamentoInfo
- Publication number
- BR0312957A BR0312957A BR0312957-8A BR0312957A BR0312957A BR 0312957 A BR0312957 A BR 0312957A BR 0312957 A BR0312957 A BR 0312957A BR 0312957 A BR0312957 A BR 0312957A
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- Prior art keywords
- 11betahsd1
- compound
- pharmaceutically acceptable
- pharmaceutical composition
- acceptable salt
- Prior art date
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- C07C49/227—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
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- C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
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- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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- C07C233/76—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
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- C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
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Abstract
"COMPOSTO OU UM SAL FARMACEUTICAMENTE ACEITáVEL DESTE, USO DO MESMO, COMPOSIçãO FARMACêUTICA, E, MéTODO PARA PRODUZIR UM EFEITO INIBIDOR DE 11BETAHSD1 EM UM ANIMAL DE SANGUE QUENTE, TAL COMO O HOMEM, EM NECESSIDADE DE TAL TRATAMENTO". Os compostos da fórmula (I): em que os grupos variáveis são como definidos neste, para o uso na inibição de 11<225>HSD1 são descritos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0217433A GB0217433D0 (en) | 2002-07-27 | 2002-07-27 | Chemical compounds |
GB0230318A GB0230318D0 (en) | 2002-12-24 | 2002-12-24 | Chemical compounds |
PCT/GB2003/003171 WO2004011410A1 (en) | 2002-07-27 | 2003-07-23 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
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BR0312957A true BR0312957A (pt) | 2005-06-14 |
Family
ID=31189605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0312957-8A BR0312957A (pt) | 2002-07-27 | 2003-07-23 | Composto ou um sal farmaceuticamente aceitável deste, uso do mesmo, composição farmacêutica, e, método para produzir um efeito inibidor de 11betahsd1 em um animal de sangue quente, tal como o homem, em necessidade de tal tratamento |
Country Status (13)
Country | Link |
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US (1) | US20050272036A1 (pt) |
EP (1) | EP1549600A1 (pt) |
JP (1) | JP2005533858A (pt) |
KR (1) | KR20050025189A (pt) |
CN (1) | CN1681763A (pt) |
AU (1) | AU2003254481A1 (pt) |
BR (1) | BR0312957A (pt) |
CA (1) | CA2494668A1 (pt) |
IL (1) | IL166219A0 (pt) |
MX (1) | MXPA05001009A (pt) |
NO (1) | NO20050065L (pt) |
WO (1) | WO2004011410A1 (pt) |
ZA (1) | ZA200500253B (pt) |
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-
2003
- 2003-07-23 BR BR0312957-8A patent/BR0312957A/pt not_active Application Discontinuation
- 2003-07-23 JP JP2004523925A patent/JP2005533858A/ja not_active Withdrawn
- 2003-07-23 AU AU2003254481A patent/AU2003254481A1/en not_active Abandoned
- 2003-07-23 WO PCT/GB2003/003171 patent/WO2004011410A1/en active Application Filing
- 2003-07-23 CA CA002494668A patent/CA2494668A1/en not_active Abandoned
- 2003-07-23 MX MXPA05001009A patent/MXPA05001009A/es not_active Application Discontinuation
- 2003-07-23 KR KR1020057001537A patent/KR20050025189A/ko not_active Application Discontinuation
- 2003-07-23 US US10/522,225 patent/US20050272036A1/en not_active Abandoned
- 2003-07-23 EP EP03771150A patent/EP1549600A1/en not_active Withdrawn
- 2003-07-23 CN CNA038224402A patent/CN1681763A/zh active Pending
-
2005
- 2005-01-06 NO NO20050065A patent/NO20050065L/no unknown
- 2005-01-10 IL IL16621905A patent/IL166219A0/xx unknown
- 2005-01-11 ZA ZA2005/00253A patent/ZA200500253B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2494668A1 (en) | 2004-02-05 |
NO20050065L (no) | 2005-04-22 |
ZA200500253B (en) | 2006-01-25 |
IL166219A0 (en) | 2006-01-15 |
CN1681763A (zh) | 2005-10-12 |
KR20050025189A (ko) | 2005-03-11 |
US20050272036A1 (en) | 2005-12-08 |
MXPA05001009A (es) | 2005-05-16 |
JP2005533858A (ja) | 2005-11-10 |
EP1549600A1 (en) | 2005-07-06 |
AU2003254481A1 (en) | 2004-02-16 |
WO2004011410A1 (en) | 2004-02-05 |
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