|
US6908744B1
(en)
*
|
2000-03-14 |
2005-06-21 |
Regeneron Pharmaceuticals, Inc. |
Methods of stimulating cartilage formation
|
|
US20050144655A1
(en)
|
2000-10-31 |
2005-06-30 |
Economides Aris N. |
Methods of modifying eukaryotic cells
|
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
GB0115256D0
(en)
|
2001-06-21 |
2001-08-15 |
Babraham Inst |
Mouse light chain locus
|
|
EP1461442B1
(en)
|
2001-11-30 |
2017-09-06 |
Amgen Fremont Inc. |
Transgenic animals bearing human ig lambda light chain genes
|
|
EP2399586A1
(en)
|
2002-01-11 |
2011-12-28 |
Jefferies, Dr., Wilfred |
Use of P97 as an enzyme delivery system for the delivery of therapeutic lysosomal enzymes
|
|
WO2003062435A1
(en)
*
|
2002-01-18 |
2003-07-31 |
Morphotek, Inc. |
A method for generating engineered cells for locus specific gene regulation and analysis
|
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
|
AU2003250074B2
(en)
|
2002-07-18 |
2010-09-09 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
|
EP1539946A4
(en)
*
|
2002-09-09 |
2006-03-15 |
California Inst Of Techn |
METHOD AND COMPOSITIONS FOR PRODUCING HUMANIZED MICE
|
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
|
EP2395017A3
(en)
|
2003-05-30 |
2012-12-19 |
Merus B.V. |
Design and use of paired variable regions of specific binding molecules
|
|
GB2408980B
(en)
*
|
2003-12-09 |
2006-06-07 |
Nat Biolog Standards Board |
Genetic reference materials
|
|
CA2580336C
(en)
|
2004-07-22 |
2016-07-19 |
Roger Kingdon Craig |
Vh heavy chain only antibodies, and vh heavy chain only dimer compounds and uses thereof
|
|
WO2007117410A2
(en)
*
|
2006-03-31 |
2007-10-18 |
Medarex, Inc. |
Transgenic animals expressing chimeric antibodies for use in preparing human antibodies
|
|
PL2374818T3
(pl)
|
2006-06-02 |
2013-05-31 |
Regeneron Pharma |
Przeciwciała o wysokim powinowactwie przeciw ludzkiemu receptorowi IL 6
|
|
WO2007147167A2
(en)
*
|
2006-06-16 |
2007-12-21 |
Porous Power Technologies, Llc |
Optimized microporous structure of electrochemical cells
|
|
CN101522716B
(zh)
|
2006-10-02 |
2013-03-20 |
瑞泽恩制药公司 |
抗人il-4受体的高亲和力人抗体
|
|
US7608693B2
(en)
|
2006-10-02 |
2009-10-27 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human IL-4 receptor
|
|
NO347649B1
(no)
|
2006-12-14 |
2024-02-12 |
Regeneron Pharma |
Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse.
|
|
EP2125894B1
(en)
|
2007-03-22 |
2018-12-19 |
Biogen MA Inc. |
Binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind cd154 and uses thereof
|
|
SG182144A1
(en)
*
|
2007-06-01 |
2012-07-30 |
Omt Inc |
Compositions and methods for inhibiting endogenous immunoglobulin genes and producing transgenic human idiotype antibodies
|
|
US7988967B2
(en)
|
2007-08-10 |
2011-08-02 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human nerve growth factor
|
|
JP5588866B2
(ja)
*
|
2007-08-10 |
2014-09-10 |
メダレックス エル.エル.シー. |
Hco32およびhco27、ならびに関連実施例
|
|
GB0718029D0
(en)
*
|
2007-09-14 |
2007-10-24 |
Iti Scotland Ltd |
Two step cluster deletion and humanisation
|
|
KR102339457B1
(ko)
|
2007-09-26 |
2021-12-14 |
추가이 세이야쿠 가부시키가이샤 |
항체 정상영역 개변체
|
|
WO2009076464A2
(en)
|
2007-12-10 |
2009-06-18 |
Aliva Biopharmaceuticals, Inc. |
Methods for sequential replacement of targeted region by homologous recombination
|
|
WO2009103082A2
(en)
*
|
2008-02-17 |
2009-08-20 |
Porous Power Technologies, Llc |
Lamination configurations for battery applications using pvdf highly porous film
|
|
US20090227163A1
(en)
*
|
2008-03-05 |
2009-09-10 |
Bernard Perry |
Protective Apparel with Porous Material Layer
|
|
US20090226683A1
(en)
*
|
2008-03-05 |
2009-09-10 |
Bernard Perry |
Porous Material Uses in Furniture
|
|
US20090223155A1
(en)
*
|
2008-03-05 |
2009-09-10 |
Bernard Perry |
Building Construction Applications for Porous Material
|
|
US20090222995A1
(en)
*
|
2008-03-05 |
2009-09-10 |
Bernard Perry |
Bedding Applications for Porous Material
|
|
EP2098536A1
(en)
|
2008-03-05 |
2009-09-09 |
4-Antibody AG |
Isolation and identification of antigen- or ligand-specific binding proteins
|
|
EP2271770B1
(en)
*
|
2008-03-31 |
2018-08-22 |
Genentech, Inc. |
Compositions and methods for treating and diagnosing asthma
|
|
EP2669298A3
(en)
*
|
2008-05-23 |
2014-02-26 |
Ablexis, LLC |
Single variable immunoglobulin domain comprising VL-DH-JL
|
|
US20100122358A1
(en)
*
|
2008-06-06 |
2010-05-13 |
Crescendo Biologics Limited |
H-Chain-only antibodies
|
|
US20090328240A1
(en)
*
|
2008-06-24 |
2009-12-31 |
Sing George L |
Genetically modified mice as predictors of immune response
|
|
AU2014203150C1
(en)
*
|
2008-06-27 |
2018-10-18 |
Merus N.V. |
Antibody producing non-human mammals
|
|
ES2445193T3
(es)
*
|
2008-06-27 |
2014-02-28 |
Merus B.V. |
Mamíferos no humanos productores de anticuerpos
|
|
WO2010039900A2
(en)
*
|
2008-09-30 |
2010-04-08 |
Aliva Biopharmaceuticals, Inc. |
Non-human mammals for the production of chimeric antibodies
|
|
JO3672B1
(ar)
|
2008-12-15 |
2020-08-27 |
Regeneron Pharma |
أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
|
|
US20130064834A1
(en)
|
2008-12-15 |
2013-03-14 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating hypercholesterolemia using antibodies to pcsk9
|
|
KR101711222B1
(ko)
|
2008-12-18 |
2017-02-28 |
에라스무스 유니버시티 메디컬 센터 로테르담 |
인간화 항체들을 발현하는 비-인간 유전자이식 동물들 및 그의 이용
|
|
US20100178567A1
(en)
*
|
2008-12-24 |
2010-07-15 |
Porous Power Technologies, Llc |
Mat Forming Spacers in Microporous Membrane Matrix
|
|
GB0905023D0
(en)
|
2009-03-24 |
2009-05-06 |
Univ Erasmus Medical Ct |
Binding molecules
|
|
MA33210B1
(fr)
|
2009-03-25 |
2012-04-02 |
Genentech Inc |
Nouveaux anticorps anti-a5b1 et leurs utilisations
|
|
JP2012527738A
(ja)
*
|
2009-05-20 |
2012-11-08 |
ポーラス パワー テクノロジーズ,エルエルシー |
微多孔膜の処理と接着剤
|
|
TWI513465B
(zh)
|
2009-06-25 |
2015-12-21 |
Regeneron Pharma |
以dll4拮抗劑與化學治療劑治療癌症之方法
|
|
KR101962476B1
(ko)
|
2009-07-03 |
2019-03-26 |
아비펩 피티와이 리미티트 |
면역성 접합체 및 그 제조방법
|
|
US9445581B2
(en)
*
|
2012-03-28 |
2016-09-20 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
ES2948572T3
(es)
*
|
2009-07-08 |
2023-09-14 |
Kymab Ltd |
Modelos de roedores y moléculas terapéuticas
|
|
ES3010323T3
(en)
|
2009-10-06 |
2025-04-02 |
Regeneron Pharma |
Genetically modified mice and engraftment
|
|
MY172472A
(en)
*
|
2009-12-10 |
2019-11-26 |
Regeneron Pharma |
Mice that make heavy chain antibodies
|
|
WO2011072266A2
(en)
|
2009-12-11 |
2011-06-16 |
Atyr Pharma, Inc. |
Aminoacyl trna synthetases for modulating hematopoiesis
|
|
JP5595517B2
(ja)
|
2009-12-21 |
2014-09-24 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
ヒト化FcγRマウス
|
|
US9315581B2
(en)
|
2009-12-23 |
2016-04-19 |
A Vipep Pty Limited |
Immuno-conjugates and methods for producing them
|
|
ES2547142T5
(es)
*
|
2010-02-08 |
2021-12-09 |
Regeneron Pharma |
Cadena ligera común de ratón
|
|
US20130045492A1
(en)
|
2010-02-08 |
2013-02-21 |
Regeneron Pharmaceuticals, Inc. |
Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
|
|
US20120021409A1
(en)
*
|
2010-02-08 |
2012-01-26 |
Regeneron Pharmaceuticals, Inc. |
Common Light Chain Mouse
|
|
US20130185821A1
(en)
*
|
2010-02-08 |
2013-07-18 |
Regeneron Pharmaceuticals, Inc. |
Common Light Chain Mouse
|
|
US9796788B2
(en)
|
2010-02-08 |
2017-10-24 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
|
WO2011101328A2
(en)
|
2010-02-18 |
2011-08-25 |
Roche Glycart Ag |
Treatment with a humanized igg class anti egfr antibody and an antibody against insulin like growth factor 1 receptor
|
|
JP5981853B2
(ja)
|
2010-02-18 |
2016-08-31 |
ジェネンテック, インコーポレイテッド |
ニューレグリンアンタゴニスト及び癌の治療におけるそれらの使用
|
|
KR101899835B1
(ko)
|
2010-03-24 |
2018-09-19 |
제넨테크, 인크. |
항-lrp6 항체
|
|
KR20210010942A
(ko)
|
2010-03-31 |
2021-01-28 |
아블렉시스, 엘엘씨 |
키메라 항체의 제조를 위한 비-인간 동물의 유전적 조작
|
|
WO2011139714A2
(en)
|
2010-04-26 |
2011-11-10 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase
|
|
AU2011248614B2
(en)
|
2010-04-27 |
2017-02-16 |
Pangu Biopharma Limited |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases
|
|
US8993723B2
(en)
|
2010-04-28 |
2015-03-31 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl-tRNA synthetases
|
|
JP6008838B2
(ja)
|
2010-04-29 |
2016-10-19 |
エータイアー ファーマ, インコーポレイテッド |
アスパラギニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
|
CA2797393C
(en)
|
2010-04-29 |
2020-03-10 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases
|
|
US9068177B2
(en)
|
2010-04-29 |
2015-06-30 |
Atyr Pharma, Inc |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases
|
|
EP2566496B1
(en)
|
2010-05-03 |
2018-02-28 |
aTyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-trna synthetases
|
|
WO2011140132A2
(en)
|
2010-05-03 |
2011-11-10 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-trna synthetases
|
|
JP5976638B2
(ja)
|
2010-05-03 |
2016-08-23 |
エータイアー ファーマ, インコーポレイテッド |
アルギニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
|
AU2011248101B2
(en)
|
2010-05-04 |
2016-10-20 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-tRNA synthetase complex
|
|
US8945541B2
(en)
|
2010-05-14 |
2015-02-03 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases
|
|
AU2011265306C1
(en)
|
2010-06-11 |
2015-01-22 |
Regeneron Pharmaceuticals, Inc. |
Production of fertile XY female animals from XY ES cells
|
|
WO2011159847A2
(en)
|
2010-06-15 |
2011-12-22 |
The Regents Of The University Of California |
Receptor tyrosine kinase-like orphan receptor 1 (ror1) single chain fv antibody fragment conjugates and methods of use thereof
|
|
CA2802591A1
(en)
*
|
2010-06-17 |
2011-12-22 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
KR101885388B1
(ko)
|
2010-06-18 |
2018-08-03 |
제넨테크, 인크. |
항-Axl 항체 및 사용 방법
|
|
MY195217A
(en)
|
2010-06-22 |
2023-01-11 |
Regeneron Pharma |
MICE Expressing An Immunoglobulin Hybrid Light Chain
|
|
CA2803792A1
(en)
|
2010-07-09 |
2012-01-12 |
Genentech, Inc. |
Anti-neuropilin antibodies and methods of use
|
|
AU2011289831C1
(en)
|
2010-07-12 |
2017-06-15 |
Pangu Biopharma Limited |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases
|
|
US20120100166A1
(en)
|
2010-07-15 |
2012-04-26 |
Zyngenia, Inc. |
Ang-2 Binding Complexes and Uses Thereof
|
|
WO2012010582A1
(en)
|
2010-07-21 |
2012-01-26 |
Roche Glycart Ag |
Anti-cxcr5 antibodies and methods of use
|
|
US10793829B2
(en)
|
2010-07-26 |
2020-10-06 |
Trianni, Inc. |
Transgenic mammals and methods of use thereof
|
|
EP2597945B1
(en)
*
|
2010-07-26 |
2020-07-22 |
Trianni, Inc. |
Transgenic animals and methods of use
|
|
US10662256B2
(en)
|
2010-07-26 |
2020-05-26 |
Trianni, Inc. |
Transgenic mammals and methods of use thereof
|
|
IL315833A
(en)
*
|
2010-08-02 |
2024-11-01 |
Regeneron Pharma |
Mice producing binding proteins containing VL regions
|
|
RU2013106216A
(ru)
|
2010-08-03 |
2014-09-10 |
Ф. Хоффманн-Ля Рош Аг |
Биомаркеры хронической лимфоцитарной лейкемии
|
|
RU2013106217A
(ru)
|
2010-08-05 |
2014-09-10 |
Ф. Хоффманн-Ля Рош Аг |
Гибридный белок из антитела против мнс и противовирусного цитокина
|
|
RU2584597C2
(ru)
|
2010-08-13 |
2016-05-20 |
Рош Гликарт Аг |
Антитела против а2 тенасцина с и способы их применения
|
|
RU2013110844A
(ru)
|
2010-08-13 |
2014-09-20 |
Дженентек, Инк. |
АНТИТЕЛА ПРОТИВ IL-1β И IL-18, ИСПОЛЬЗУЕМЫЕ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ
|
|
ES2655616T3
(es)
|
2010-08-13 |
2018-02-20 |
Roche Glycart Ag |
Anticuerpos anti-FAP y procedimientos de uso
|
|
WO2012027611A2
(en)
|
2010-08-25 |
2012-03-01 |
Atyr Pharma, Inc. |
INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF TYROSYL-tRNA SYNTHETASES
|
|
AU2011295919A1
(en)
|
2010-08-31 |
2013-03-07 |
Genentech, Inc. |
Biomarkers and methods of treatment
|
|
AU2011325871B2
(en)
|
2010-11-05 |
2016-02-04 |
Medvet Science Pty Ltd |
Markers of endothelial progenitor cells and uses thereof
|
|
US8772457B2
(en)
|
2010-11-10 |
2014-07-08 |
Genentech, Inc. |
BACE1 antibodies
|
|
JO3756B1
(ar)
*
|
2010-11-23 |
2021-01-31 |
Regeneron Pharma |
اجسام مضادة بشرية لمستقبلات الجلوكاجون
|
|
US8771696B2
(en)
|
2010-11-23 |
2014-07-08 |
Regeneron Pharmaceuticals, Inc. |
Method of reducing the severity of stress hyperglycemia with human antibodies to the glucagon receptor
|
|
WO2012083132A2
(en)
|
2010-12-16 |
2012-06-21 |
Genentech, Inc. |
Diagnosis and treatments relating to th2 inhibition
|
|
NZ610976A
(en)
|
2010-12-20 |
2015-07-31 |
Genentech Inc |
Anti-mesothelin antibodies and immunoconjugates
|
|
SG191219A1
(en)
|
2010-12-22 |
2013-07-31 |
Genentech Inc |
Anti-pcsk9 antibodies and methods of use
|
|
EP2661282A1
(en)
|
2011-01-03 |
2013-11-13 |
F.Hoffmann-La Roche Ag |
A pharmaceutical composition of a complex of an anti-dig antibody and digoxigenin that is conjugated to a peptide
|
|
CA3027071A1
(en)
|
2011-01-14 |
2013-07-19 |
The Regents Of The University Of California |
Therapeutic antibodies against ror-1 protein and methods for use of same
|
|
EP2650016A1
(en)
|
2011-01-28 |
2013-10-16 |
Sanofi |
Human antibodies to PSCK9 for use in methods of treatment based on particular dosage regimens (11565)
|
|
MX347602B
(es)
|
2011-01-28 |
2017-05-03 |
Sanofi Biotechnology |
Composiciones farmaceuticas que comprenden anticuerpos humanos frente a pcsk9.
|
|
MX375113B
(es)
|
2011-02-08 |
2025-03-04 |
Medimmune Llc |
Anticuerpos que se unen específicamente a la toxina alfa de staphylococcus aureus y métodos de uso.
|
|
KR102714361B1
(ko)
|
2011-02-15 |
2024-10-11 |
리제너론 파마슈티칼스 인코포레이티드 |
인간화된 m-csf 마우스
|
|
HUE024534T2
(hu)
|
2011-02-25 |
2016-01-28 |
Regeneron Pharma |
ADAM6 egerek
|
|
EP2686016B1
(en)
|
2011-03-14 |
2019-05-01 |
Cellmid Limited |
Antibody recognizing n-domain of midkine
|
|
HUE041335T2
(hu)
|
2011-03-29 |
2019-05-28 |
Roche Glycart Ag |
Antitest FC-variánsok
|
|
TW201249867A
(en)
|
2011-04-01 |
2012-12-16 |
Astellas Pharma Inc |
Novel anti-human il-23 receptor antibody
|
|
MX342240B
(es)
|
2011-04-07 |
2016-09-21 |
Genentech Inc |
Anticuerpos anti-fgfr4 y metodos de uso.
|
|
CN103619877B
(zh)
|
2011-04-21 |
2018-01-02 |
加文医学研究所 |
修饰的可变结构域分子及其产生和使用方法b
|
|
AR088782A1
(es)
|
2011-04-29 |
2014-07-10 |
Sanofi Sa |
Sistemas de ensayo y metodos para identificar y caracterizar farmacos hipolipemiantes
|
|
US8679767B2
(en)
|
2011-05-12 |
2014-03-25 |
Genentech, Inc. |
Multiple reaction monitoring LC-MS/MS method to detect therapeutic antibodies in animal samples using framework signature peptides
|
|
DK2527842T3
(da)
|
2011-05-12 |
2013-09-08 |
Regeneron Pharma |
Neuropeptidfrisætningsanalyse til natriumkanaler
|
|
LT2710035T
(lt)
|
2011-05-16 |
2017-06-26 |
F. Hoffmann-La Roche Ag |
Fgfr1 agonistai ir jų naudojimo būdai
|
|
DK2714738T3
(en)
|
2011-05-24 |
2019-01-28 |
Zyngenia Inc |
MULTIVALENT AND MONOVALENT MULTISPECIFIC COMPLEXES AND THEIR APPLICATIONS
|
|
ES2828482T3
(es)
|
2011-06-13 |
2021-05-26 |
Csl Ltd |
Anticuerpos contra el g-csfr y su uso
|
|
WO2012171996A1
(en)
|
2011-06-15 |
2012-12-20 |
F. Hoffmann-La Roche Ag |
Anti-human epo receptor antibodies and methods of use
|
|
US20130004484A1
(en)
|
2011-06-30 |
2013-01-03 |
Genentech, Inc. |
Anti-c-met antibody formulations
|
|
CA2841376C
(en)
|
2011-07-05 |
2023-02-28 |
Duke University |
N-terminal deleted gp120 immunogens
|
|
US9150846B2
(en)
|
2011-07-05 |
2015-10-06 |
Bioasis Technologies, Inc. |
P97-antibody conjugates and methods of use
|
|
US9120858B2
(en)
|
2011-07-22 |
2015-09-01 |
The Research Foundation Of State University Of New York |
Antibodies to the B12-transcobalamin receptor
|
|
WO2013015821A1
(en)
|
2011-07-22 |
2013-01-31 |
The Research Foundation Of State University Of New York |
Antibodies to the b12-transcobalamin receptor
|
|
AR087305A1
(es)
|
2011-07-28 |
2014-03-12 |
Regeneron Pharma |
Formulaciones estabilizadas que contienen anticuerpos anti-pcsk9, metodo de preparacion y kit
|
|
DK2739649T3
(en)
|
2011-08-05 |
2018-01-08 |
Bioasis Technologies Inc |
P97 FRAGMENTS WITH TRANSFER ACTIVITY
|
|
IL273982B2
(en)
|
2011-08-05 |
2023-03-01 |
Regeneron Pharma |
Humanized mice possess a universal light chain
|
|
KR101999867B1
(ko)
|
2011-08-11 |
2019-07-12 |
아스텔라스세이야쿠 가부시키가이샤 |
신규 항 인간 ngf 항체
|
|
US20140363438A1
(en)
|
2011-08-17 |
2014-12-11 |
Genentech, Inc. |
Neuregulin antibodies and uses thereof
|
|
RU2014109985A
(ru)
|
2011-08-17 |
2015-09-27 |
Дженентек, Инк. |
Ингибирование ангиогенеза в рефрактерных опухолях
|
|
CN103874709B
(zh)
|
2011-08-19 |
2016-12-21 |
瑞泽恩制药公司 |
抗tie2抗体及其用途
|
|
CN103890006A
(zh)
|
2011-08-23 |
2014-06-25 |
罗切格利卡特公司 |
抗mcsp抗体
|
|
MX356947B
(es)
|
2011-08-23 |
2018-06-20 |
Roche Glycart Ag |
Anticuerpos bioespecíficos específicos para antígenos que activan células t y un antígeno tumoral y métodos de uso.
|
|
CN103781801B
(zh)
|
2011-08-23 |
2018-02-09 |
罗切格利卡特公司 |
包含两个Fab片段的无Fc的抗体及使用方法
|
|
MX2014003094A
(es)
|
2011-09-15 |
2014-04-25 |
Genentech Inc |
Metodos para promover diferenciacion.
|
|
PL4252857T3
(pl)
|
2011-09-16 |
2025-03-03 |
Regeneron Pharmaceuticals, Inc. |
Sposoby redukowania poziomów lipoproteiny(a) poprzez podawanie inhibitora proproteinowej konwertazy subtylizyny keksyny-9 (pcsk9)
|
|
WO2013041845A2
(en)
|
2011-09-19 |
2013-03-28 |
Kymab Limited |
Animals, repertoires & methods
|
|
EP2757875B2
(en)
|
2011-09-19 |
2023-03-22 |
Kymab Limited |
Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics
|
|
KR20140064971A
(ko)
|
2011-09-19 |
2014-05-28 |
제넨테크, 인크. |
c-met 길항제 및 B-raf 길항제를 포함하는 조합 치료
|
|
CA2791109C
(en)
|
2011-09-26 |
2021-02-16 |
Merus B.V. |
Generation of binding molecules
|
|
WO2013045916A1
(en)
|
2011-09-26 |
2013-04-04 |
Kymab Limited |
Chimaeric surrogate light chains (slc) comprising human vpreb
|
|
US10092638B2
(en)
|
2011-10-03 |
2018-10-09 |
Duke University |
GP120 immunogens and methods inducing neutralizing antibodies to human immunodeficiency virus
|
|
US9663573B2
(en)
|
2011-10-05 |
2017-05-30 |
Genentech, Inc. |
Methods of treating liver conditions using Notch2 antagonists
|
|
LT2766393T
(lt)
|
2011-10-14 |
2018-10-10 |
F. Hoffmann-La Roche Ag |
Antikūnai prieš htra1 ir jų naudojimo būdai
|
|
EP2766000A2
(en)
|
2011-10-15 |
2014-08-20 |
F.Hoffmann-La Roche Ag |
Scd1 antagonists for treating cancer
|
|
US10246509B2
(en)
|
2011-10-17 |
2019-04-02 |
Regeneron Pharmaceuticals, Inc. |
Restricted immunoglobulin heavy chain mice
|
|
WO2013059531A1
(en)
|
2011-10-20 |
2013-04-25 |
Genentech, Inc. |
Anti-gcgr antibodies and uses thereof
|
|
DK2770821T3
(da)
|
2011-10-28 |
2017-11-27 |
Regeneron Pharma |
Genetisk modificerede major histocompatibility-kompleks-mus
|
|
EP2770823A4
(en)
|
2011-10-28 |
2015-12-09 |
Trianni Inc |
TRANSGENIC ANIMALS AND METHOD FOR THEIR USE
|
|
GB2496375A
(en)
*
|
2011-10-28 |
2013-05-15 |
Kymab Ltd |
A non-human assay vertebrate comprising human antibody loci and human epitope knock-in, and uses thereof
|
|
SMT202100243T1
(it)
|
2011-10-28 |
2021-05-07 |
Regeneron Pharma |
Topi con recettori delle cellule t geneticamente modificati
|
|
KR101926442B1
(ko)
|
2011-10-28 |
2018-12-12 |
리제너론 파아마슈티컬스, 인크. |
키메라 주요 조직적합성 복합체 (mhc) ii 분자들을 발현하는 유전자 변형된 마우스
|
|
AU2012327878A1
(en)
|
2011-10-28 |
2014-05-29 |
Patrys Limited |
PAT-LM1 epitopes and methods for using same
|
|
US9591835B2
(en)
|
2011-10-28 |
2017-03-14 |
Regeneron Pharmaceuticals, Inc. |
Genetically modified major histocompatibility complex animals
|
|
EP2776051A4
(en)
|
2011-10-28 |
2015-06-17 |
Hoffmann La Roche |
THERAPEUTIC COMBINATIONS AND METHOD FOR THE TREATMENT OF MELANOMA
|
|
US9043996B2
(en)
|
2011-10-28 |
2015-06-02 |
Regeneron Pharmaceuticals, Inc. |
Genetically modified major histocompatibility complex animals
|
|
BR112014012005A2
(pt)
|
2011-11-21 |
2017-12-19 |
Genentech Inc |
composições, métodos, formulação farmacêutica e artigo
|
|
GB201122047D0
(en)
|
2011-12-21 |
2012-02-01 |
Kymab Ltd |
Transgenic animals
|
|
US9253965B2
(en)
*
|
2012-03-28 |
2016-02-09 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
WO2013083497A1
(en)
|
2011-12-06 |
2013-06-13 |
F. Hoffmann-La Roche Ag |
Antibody formulation
|
|
SG11201403326VA
(en)
|
2011-12-20 |
2014-07-30 |
Regeneron Pharma |
Humanized light chain mice
|
|
BR112014012667A2
(pt)
|
2011-12-22 |
2018-10-09 |
F Hoffmann-La Roche Ag |
vetor de expressão, usos de vetor de expressão, método de transfecção de células eucarióticas, uso de método, uso de célula, métodos de produção de anticorpos e método de transfecção
|
|
HK1200849A1
(en)
|
2011-12-22 |
2015-08-14 |
F. Hoffmann-La Roche Ag |
Full length antibody display system for eukaryotic cells and its use
|
|
RU2639519C2
(ru)
|
2011-12-22 |
2017-12-21 |
Ф.Хоффманн-Ля Рош Аг |
Комбинации элементов экспрессионного вектора, новые способы получения клеток-продуцентов и их применение для рекомбинантного получения полипептидов
|
|
WO2013094723A1
(ja)
|
2011-12-22 |
2013-06-27 |
アステラス製薬株式会社 |
新規抗ヒトctgf抗体
|
|
WO2013096791A1
(en)
|
2011-12-23 |
2013-06-27 |
Genentech, Inc. |
Process for making high concentration protein formulations
|
|
CA2862424A1
(en)
|
2012-01-18 |
2013-07-25 |
Genentech, Inc. |
Methods of using fgf19 modulators
|
|
IN2014DN05885A
(OSRAM)
|
2012-01-18 |
2015-06-05 |
Hoffmann La Roche |
|
|
WO2013116609A1
(en)
|
2012-02-01 |
2013-08-08 |
Regeneron Pharmaceuticals, Inc. |
Humanized rodents that express heavy chains containing vl domains
|
|
WO2013120056A1
(en)
|
2012-02-11 |
2013-08-15 |
Genentech, Inc. |
R-spondin translocations and methods using the same
|
|
BR112014018005B1
(pt)
|
2012-02-15 |
2021-06-29 |
F. Hoffmann-La Roche Ag |
Uso de um complexo não covalente imobilizado
|
|
CN104334196B
(zh)
|
2012-02-16 |
2018-04-10 |
Atyr 医药公司 |
用于治疗自身免疫疾病和炎性疾病的组氨酰‑tRNA合成酶
|
|
WO2013129454A1
(ja)
|
2012-02-28 |
2013-09-06 |
アステラス製薬株式会社 |
新規抗ヒトil-23受容体抗体
|
|
WO2013130981A1
(en)
|
2012-03-02 |
2013-09-06 |
Regeneron Pharmaceuticals, Inc. |
Human antibodies to clostridium difficile toxins
|
|
EP3165086A1
(en)
|
2012-03-06 |
2017-05-10 |
Regeneron Pharmaceuticals, Inc. |
Common light chain mouse
|
|
MX365139B
(es)
|
2012-03-13 |
2019-05-24 |
Hoffmann La Roche |
Uso de una terapia combinada de bevacizumab y paclitaxel en el tratamiento de cáncer de ovario epitelial resistente al platino, carcinoma de las trompas de falopio resistente al platino, o carcinoma peritoneal primario resistente al platino.
|
|
RU2664473C2
(ru)
*
|
2012-03-16 |
2018-08-17 |
Регенерон Фармасьютикалз, Инк. |
ОТЛИЧНЫЕ ОТ ЧЕЛОВЕКА ЖИВОТНЫЕ, ЭКСПРЕССИРУЮЩИЕ ЧУВСТВИТЕЛЬНЫЕ К pН ПОСЛЕДОВАТЕЛЬНОСТИ ИММУНОГЛОБУЛИНОВ
|
|
EP2825036B1
(en)
|
2012-03-16 |
2018-05-02 |
Regeneron Pharmaceuticals, Inc. |
Histidine engineered light chain antibodies and genetically modified rodents for generating the same
|
|
US20140013456A1
(en)
|
2012-03-16 |
2014-01-09 |
Regeneron Pharmaceuticals, Inc. |
Histidine Engineered Light Chain Antibodies and Genetically Modified Non-Human Animals for Generating the Same
|
|
AU2013204581B2
(en)
|
2012-03-16 |
2015-06-25 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals expressing pH-sensitive immunoglobulin sequences
|
|
MX2014011500A
(es)
|
2012-03-27 |
2014-12-05 |
Genentech Inc |
Diagnosticos y tratamientos relacionados a inhibidores her3.
|
|
US10251377B2
(en)
|
2012-03-28 |
2019-04-09 |
Kymab Limited |
Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies
|
|
WO2013144567A1
(en)
|
2012-03-28 |
2013-10-03 |
Kymab Limited |
Transgenic non-human vertebrate for the expression of class - switched, fully human, antibodies
|
|
GB2502127A
(en)
|
2012-05-17 |
2013-11-20 |
Kymab Ltd |
Multivalent antibodies and in vivo methods for their production
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
TWI619729B
(zh)
|
2012-04-02 |
2018-04-01 |
再生元醫藥公司 |
抗-hla-b*27抗體及其用途
|
|
CN120383672A
(zh)
|
2012-04-20 |
2025-07-29 |
美勒斯公司 |
用于产生免疫球蛋白样分子的方法和手段
|
|
SG11201406547YA
(en)
|
2012-04-25 |
2014-11-27 |
Regeneron Pharma |
Nuclease-mediated targeting with large targeting vectors
|
|
US9056910B2
(en)
|
2012-05-01 |
2015-06-16 |
Genentech, Inc. |
Anti-PMEL17 antibodies and immunoconjugates
|
|
JO3820B1
(ar)
|
2012-05-03 |
2021-01-31 |
Regeneron Pharma |
أجسام مضادة بشرية لـ fel d1وطرق لاستخدامها
|
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
|
WO2013177470A1
(en)
|
2012-05-23 |
2013-11-28 |
Genentech, Inc. |
Selection method for therapeutic agents
|
|
AR092325A1
(es)
|
2012-05-31 |
2015-04-15 |
Regeneron Pharma |
Formulaciones estabilizadas que contienen anticuerpos anti-dll4 y kit
|
|
RU2014153674A
(ru)
*
|
2012-06-05 |
2016-07-27 |
Регенерон Фармасьютикалз, Инк. |
Способ получения полностью человеческих биспецифических антител с применением общей легкой цепи
|
|
PT3597037T
(pt)
*
|
2012-06-12 |
2021-06-01 |
Regeneron Pharma |
Animais não humanos humanizados com lócus de cadeia pesada de imunoglobulina restrito
|
|
EP2861624A1
(en)
|
2012-06-15 |
2015-04-22 |
F. Hoffmann-La Roche AG |
Anti-pcsk9 antibodies, formulations, dosing, and methods of use
|
|
KR20150030755A
(ko)
|
2012-07-04 |
2015-03-20 |
에프. 호프만-라 로슈 아게 |
항-바이오틴 항체 및 사용 방법
|
|
CN104394886B
(zh)
|
2012-07-04 |
2017-05-24 |
弗·哈夫曼-拉罗切有限公司 |
抗茶碱抗体及使用方法
|
|
AU2013285422B2
(en)
|
2012-07-04 |
2017-04-27 |
F. Hoffmann-La Roche Ag |
Covalently linked antigen-antibody conjugates
|
|
ES2743401T3
(es)
|
2012-07-05 |
2020-02-19 |
Hoffmann La Roche |
Sistema de expresión y secreción
|
|
KR20150030698A
(ko)
|
2012-07-09 |
2015-03-20 |
제넨테크, 인크. |
항-cd79b 항체를 포함하는 면역접합체
|
|
SG11201500087VA
(en)
|
2012-07-09 |
2015-02-27 |
Genentech Inc |
Immunoconjugates comprising anti-cd22 antibodies
|
|
AU2013288930A1
(en)
|
2012-07-09 |
2014-12-04 |
Genentech, Inc. |
Immunoconjugates comprising anti-CD79b antibodies
|
|
AR091701A1
(es)
|
2012-07-09 |
2015-02-25 |
Genentech Inc |
Anticuerpos anti-cd22 e inmunoconjugados
|
|
PT3210627T
(pt)
|
2012-07-12 |
2023-03-23 |
Hangzhou Dac Biotech Co Ltd |
Conjugados de moléculas de ligação celular com agentes citotóxicos
|
|
MX361337B
(es)
|
2012-07-13 |
2018-12-04 |
Roche Glycart Ag |
Anticuerpos biespecificos anti-factor de crecimiento endotelial vascular humano (vegf) / anti-angiopoyetina-2 humana (ang-2) y su uso en el tratamiento de enfermedades vasculares oculares.
|
|
WO2014018375A1
(en)
|
2012-07-23 |
2014-01-30 |
Xenon Pharmaceuticals Inc. |
Cyp8b1 and uses thereof in therapeutic and diagnostic methods
|
|
AU2013296557B2
(en)
|
2012-07-31 |
2019-04-18 |
Bioasis Technologies Inc. |
Dephosphorylated lysosomal storage disease proteins and methods of use thereof
|
|
CN104507498A
(zh)
|
2012-08-07 |
2015-04-08 |
霍夫曼-拉罗奇有限公司 |
用于治疗成胶质细胞瘤的组合疗法
|
|
RU2690675C2
(ru)
|
2012-08-21 |
2019-06-05 |
Санофи Байотекнолоджи |
Способы лечения или предотвращения астмы посредством введения антагониста il-4r
|
|
KR102355959B1
(ko)
|
2012-08-23 |
2022-01-27 |
어젠시스 인코포레이티드 |
158p1d7 단백질에 결합하는 항체 약물 컨쥬게이트(adc)
|
|
ES2702315T3
(es)
|
2012-08-24 |
2019-02-28 |
Univ California |
Anticuerpos y vacunas para su uso en tratar cánceres ROR1 e inhibir metástasis
|
|
EP2703008A1
(en)
|
2012-08-31 |
2014-03-05 |
Sanofi |
Human antibodies to PCSK9 for use in methods of treating particular groups of subjects
|
|
EP2703009A1
(en)
|
2012-08-31 |
2014-03-05 |
Sanofi |
Combination treatments involving antibodies to human PCSK9
|
|
EP2706070A1
(en)
|
2012-09-06 |
2014-03-12 |
Sanofi |
Combination treatments involving antibodies to human PCSK9
|
|
ES2981062T3
(es)
|
2012-09-07 |
2024-10-07 |
Regeneron Pharma |
Métodos para el tratamiento de la dermatitis atópica administrando un antagonista de IL-4R
|
|
KR102473555B1
(ko)
|
2012-09-07 |
2022-12-05 |
예일 유니버시티 |
유전적으로 변형된 비-인간 동물 및 이것들의 사용 방법
|
|
US10087250B2
(en)
|
2012-10-08 |
2018-10-02 |
Roche Glycart Ag |
Fc-free antibodies comprising two fab-fragments and methods of use
|
|
EP2906681B1
(en)
*
|
2012-10-12 |
2019-01-09 |
GlaxoSmithKline Biologicals S.A. |
Methods of host cell modification
|
|
WO2014071358A2
(en)
|
2012-11-05 |
2014-05-08 |
Foundation Medicine, Inc. |
Novel ntrk1 fusion molecules and uses thereof
|
|
AU2013337264B2
(en)
|
2012-11-05 |
2018-03-08 |
Foundation Medicine, Inc. |
Novel fusion molecules and uses thereof
|
|
IL311744B2
(en)
|
2012-11-05 |
2025-10-01 |
Regeneron Pharma |
Genetically modified non-human animals and methods of using them
|
|
DK2917360T3
(da)
|
2012-11-06 |
2020-03-30 |
Medimmune Llc |
Antistoffer mod S. aureus-overflade-determinanter
|
|
MX2015005757A
(es)
|
2012-11-08 |
2015-11-18 |
Hoffmann La Roche |
Proteinas ligantes de antigeno her3 de union a la horquilla beta de her3.
|
|
MA38176A1
(fr)
|
2012-11-13 |
2017-06-30 |
Genentech Inc |
Nouvel anticorps anti-hemagglutinine, utile pour le traitement, l'inhibition ou la prévention de l’infection virale a grippe a
|
|
AR093445A1
(es)
|
2012-11-14 |
2015-06-10 |
Regeneron Pharma |
Metodos para tratar el cancer de ovario con antagonistas de dll4
|
|
WO2014080251A1
(en)
|
2012-11-24 |
2014-05-30 |
Hangzhou Dac Biotech Co., Ltd. |
Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
|
|
PL3653049T3
(pl)
|
2012-12-14 |
2024-02-26 |
Omniab, Inc. |
Polinukleotydy kodujące przeciwciała gryzoni z ludzkimi idiotypami i zwierzęta je zawierające
|
|
WO2014107739A1
(en)
|
2013-01-07 |
2014-07-10 |
Eleven Biotherapeutics, Inc. |
Antibodies against pcsk9
|
|
EP3939614A1
(en)
|
2013-01-18 |
2022-01-19 |
Foundation Medicine, Inc. |
Methods of treating cholangiocarcinoma
|
|
WO2014116749A1
(en)
|
2013-01-23 |
2014-07-31 |
Genentech, Inc. |
Anti-hcv antibodies and methods of using thereof
|
|
WO2014124156A1
(en)
|
2013-02-06 |
2014-08-14 |
Regeneron Pharmaceuticals, Inc. |
B cell lineage based immunogen design with humanized animals
|
|
SG11201505762XA
(en)
|
2013-02-07 |
2015-08-28 |
Csl Ltd |
Il-11r binding proteins and uses thereof
|
|
CN109913495B
(zh)
|
2013-02-20 |
2022-11-25 |
瑞泽恩制药公司 |
大鼠的遗传修饰
|
|
LT2958938T
(lt)
*
|
2013-02-20 |
2019-07-25 |
Regeneron Pharmaceuticals, Inc. |
Pelės, ekspresuojančios humanizuotus t ląstelių koreceptorius
|
|
SMT201800435T1
(it)
|
2013-02-20 |
2018-09-13 |
Regeneron Pharma |
Animali non umani con sequenze della catena pesante dell’immunoglobulina modificate riferimento incrociato a domande correlate
|
|
HK1211235A1
(en)
|
2013-02-22 |
2016-05-20 |
霍夫曼-拉罗奇有限公司 |
Methods of treating cancer and preventing drug resistance
|
|
US20150342163A1
(en)
|
2013-02-22 |
2015-12-03 |
Regeneron Pharmaceuticals, Inc. |
Genetically modified major histocompatibility complex mice
|
|
EP2958937B1
(en)
|
2013-02-22 |
2018-08-15 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing humanized major histocompatibility complex
|
|
US20140242083A1
(en)
|
2013-02-26 |
2014-08-28 |
Roche Glycart Ag |
Anti-mcsp antibodies
|
|
KR20150123250A
(ko)
|
2013-03-06 |
2015-11-03 |
제넨테크, 인크. |
암 약물 내성의 치료 및 예방 방법
|
|
EP4249507A3
(en)
*
|
2013-03-11 |
2023-12-27 |
Regeneron Pharmaceuticals, Inc. |
Transgenic mice expressing chimeric major histocompatibility complex (mhc) class ii molecules
|
|
AU2014244020B2
(en)
*
|
2013-03-13 |
2020-06-04 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
|
EP2970433B1
(en)
|
2013-03-13 |
2019-09-18 |
Bioasis Technologies Inc. |
Fragments of p97 and uses thereof
|
|
CN105189545A
(zh)
|
2013-03-13 |
2015-12-23 |
瑞泽恩制药公司 |
常见轻链小鼠
|
|
EP2970448B1
(en)
|
2013-03-14 |
2021-11-03 |
Regeneron Pharmaceuticals, Inc. |
Human antibodies to grem 1
|
|
RU2015139054A
(ru)
|
2013-03-14 |
2017-04-19 |
Дженентек, Инк. |
Способы лечения рака и профилактики лекарственной резистентности рака
|
|
EP3841876A1
(en)
|
2013-03-14 |
2021-06-30 |
Erasmus University Medical Center Rotterdam |
Transgenic mouse for antibody production
|
|
EP2968540A2
(en)
|
2013-03-14 |
2016-01-20 |
Genentech, Inc. |
Combinations of a mek inhibitor compound with an her3/egfr inhibitor compound and methods of use
|
|
WO2014159835A1
(en)
|
2013-03-14 |
2014-10-02 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
HK1211963A1
(en)
|
2013-03-15 |
2016-06-03 |
豪夫迈.罗氏有限公司 |
Compositions and methods for diagnosis and treatment of hepatic cancers
|
|
CA2907181C
(en)
|
2013-03-15 |
2023-10-17 |
Viktor Roschke |
Multivalent and monovalent multispecific complexes and their uses
|
|
AR095517A1
(es)
|
2013-03-15 |
2015-10-21 |
Genentech Inc |
ANTICUERPOS CONTRA EL RECEPTOR QUIMIOATRAYENTE EXPRESADO EN CÉLULAS T HELPER 2 (ANTI-CRTh2) Y MÉTODOS DE USO
|
|
RU2661111C2
(ru)
|
2013-03-15 |
2018-07-11 |
Ац Иммуне С.А. |
Антитела к тау и способы применения
|
|
WO2014144292A2
(en)
|
2013-03-15 |
2014-09-18 |
Sanofi Pasteur Biologics , Llc |
Antibodies against clostridium difficile toxins and methods of using the same
|
|
KR20220053691A
(ko)
|
2013-03-15 |
2022-04-29 |
제넨테크, 인크. |
Pd-1 및 pd-l1 관련 상태를 치료하기 위한 바이오마커 및 방법
|
|
EA038512B1
(ru)
|
2013-03-15 |
2021-09-08 |
Регенерон Фармасьютикалз, Инк. |
Конъюгаты майтанзиноидов и их терапевтическое применение
|
|
EP2968537A1
(en)
|
2013-03-15 |
2016-01-20 |
Genentech, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
|
US10993420B2
(en)
|
2013-03-15 |
2021-05-04 |
Erasmus University Medical Center |
Production of heavy chain only antibodies in transgenic mammals
|
|
US9788534B2
(en)
|
2013-03-18 |
2017-10-17 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
SG10201808935WA
(en)
*
|
2013-04-16 |
2018-11-29 |
Regeneron Pharma |
Targeted modification of rat genome
|
|
KR20210094669A
(ko)
|
2013-04-29 |
2021-07-29 |
에프. 호프만-라 로슈 아게 |
인간 fcrn-결합 변형된 항체 및 사용 방법
|
|
TW201920285A
(zh)
|
2013-04-29 |
2019-06-01 |
瑞士商赫孚孟拉羅股份公司 |
遏止FcRn結合之抗IGF-1R抗體及其治療血管性眼疾之用途
|
|
US20160068613A1
(en)
|
2013-04-29 |
2016-03-10 |
Hoffmann-La Roche Inc. |
Fc-receptor binding modified asymmetric antibodies and methods of use
|
|
US9783618B2
(en)
|
2013-05-01 |
2017-10-10 |
Kymab Limited |
Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics
|
|
US11707056B2
(en)
*
|
2013-05-02 |
2023-07-25 |
Kymab Limited |
Animals, repertoires and methods
|
|
US9783593B2
(en)
|
2013-05-02 |
2017-10-10 |
Kymab Limited |
Antibodies, variable domains and chains tailored for human use
|
|
US20140331339A1
(en)
*
|
2013-05-03 |
2014-11-06 |
Kymab Limited |
Transgenic Non-Human Assay Vertebrates, Assays and Kits
|
|
PH12021550015A1
(en)
|
2013-05-20 |
2022-05-11 |
Genentech Inc |
Anti-transferrin receptor antibodies and methods of use
|
|
TWI682780B
(zh)
|
2013-05-30 |
2020-01-21 |
美商再生元醫藥公司 |
醫藥組成物用於製造治療與pcsk9功能獲得性突變有關之體染色體顯性高膽固醇血症的藥物之用途
|
|
US10111953B2
(en)
|
2013-05-30 |
2018-10-30 |
Regeneron Pharmaceuticals, Inc. |
Methods for reducing remnant cholesterol and other lipoprotein fractions by administering an inhibitor of proprotein convertase subtilisin kexin-9 (PCSK9)
|
|
EP2810955A1
(en)
|
2013-06-07 |
2014-12-10 |
Sanofi |
Methods for inhibiting atherosclerosis by administering an inhibitor of PCSK9
|
|
EP2862877A1
(en)
|
2013-10-18 |
2015-04-22 |
Sanofi |
Methods for inhibiting atherosclerosis by administering an inhibitor of PCSK9
|
|
CA2914721A1
(en)
|
2013-06-07 |
2014-12-11 |
Regeneron Pharmaceuticals, Inc. |
Methods for inhibiting atherosclerosis by administering an inhibitor of pcsk9
|
|
EP3613432B1
(en)
|
2013-06-21 |
2025-08-06 |
Sanofi Biotechnology |
Methods for treating nasal polyposis by administering an il-4r antagonist
|
|
CN105722534B
(zh)
|
2013-08-01 |
2019-05-31 |
艾更斯司股份有限公司 |
结合cd37蛋白的抗体药物偶联物(adc)
|
|
AU2014305873B2
(en)
|
2013-08-07 |
2017-08-31 |
President And Fellows Of Harvard College |
LincRNA-deficient non-human animals
|
|
AR097293A1
(es)
|
2013-08-09 |
2016-03-02 |
Astellas Pharma Inc |
Anticuerpo contra el receptor de tslp humana
|
|
WO2015027154A2
(en)
|
2013-08-23 |
2015-02-26 |
Regeneron Pharmaceuticals, Inc. |
Diagnostic tests and methods for assessing safety, efficacy or outcome of allergen-specific immunotherapy (sit)
|
|
CA2921412C
(en)
|
2013-08-26 |
2024-05-28 |
Regeneron Pharmaceuticals, Inc. |
Pharmaceutical compositions comprising macrolide diastereomers, methods of their synthesis and therapeutic uses
|
|
EP3038657A2
(en)
|
2013-08-28 |
2016-07-06 |
Bioasis Technologies Inc. |
Cns-targeted conjugates having modified fc regions and methods of use thereof
|
|
US10617755B2
(en)
|
2013-08-30 |
2020-04-14 |
Genentech, Inc. |
Combination therapy for the treatment of glioblastoma
|
|
US10456470B2
(en)
|
2013-08-30 |
2019-10-29 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of glioblastoma
|
|
CN115124573A
(zh)
|
2013-09-02 |
2022-09-30 |
杭州多禧生物科技有限公司 |
应用于细胞结合分子-药物共轭体的新型细胞毒性分子
|
|
AR097685A1
(es)
|
2013-09-17 |
2016-04-06 |
Genentech Inc |
Métodos de uso de anticuerpos anti-lgr5
|
|
RU2019121863A
(ru)
*
|
2013-09-18 |
2019-08-29 |
Регенерон Фармасьютикалз, Инк. |
Антитела со встроенным в легкие цепи гистидином и генетически модифицированные отличные от человека животные для их получения
|
|
ES2844174T3
(es)
*
|
2013-09-18 |
2021-07-21 |
Kymab Ltd |
Métodos, células y organismos
|
|
ES2993142T3
(en)
*
|
2013-10-01 |
2024-12-23 |
Kymab Ltd |
Animal models and therapeutic molecules
|
|
PL3055333T4
(pl)
|
2013-10-11 |
2020-07-27 |
Sanofi Biotechnology |
Wykorzystanie inhibitora pcsk9 do leczenia hyperlipidemii
|
|
RU2016117978A
(ru)
|
2013-10-11 |
2017-11-17 |
Дженентек, Инк. |
Ингибиторы nsp4 и способы их применения
|
|
BR112016008477A2
(pt)
|
2013-10-18 |
2017-10-03 |
Genentech Inc |
Corpos, ácido nucleico, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica e usos do anticorpo
|
|
CA2924873A1
(en)
|
2013-10-23 |
2015-04-30 |
Genentech, Inc. |
Methods of diagnosing and treating eosinophilic disorders
|
|
PL3065774T3
(pl)
|
2013-11-06 |
2021-12-13 |
Janssen Biotech, Inc |
Przeciwciała anty-ccl17
|
|
JP6616298B2
(ja)
|
2013-11-12 |
2019-12-04 |
サノフィ・バイオテクノロジー |
Pcsk9阻害剤と共に使用するための投薬レジメン
|
|
PT3071597T
(pt)
|
2013-11-21 |
2020-10-08 |
Hoffmann La Roche |
Anticorpos anti-alfa-sinucleína e métodos de utilização
|
|
SMT201800653T1
(it)
|
2013-12-11 |
2019-01-11 |
Regeneron Pharma |
Metodi e composizioni per la modificazione indirizzata a bersaglio di un genoma
|
|
JP6174811B2
(ja)
|
2013-12-11 |
2017-08-02 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
ゲノムの標的改変のための方法及び組成物
|
|
AU2014362238A1
(en)
|
2013-12-13 |
2016-06-09 |
Genentech, Inc. |
Anti-CD33 antibodies and immunoconjugates
|
|
AU2014364606A1
(en)
|
2013-12-17 |
2016-07-07 |
Genentech, Inc. |
Combination therapy comprising OX40 binding agonists and PD-1 axis binding antagonists
|
|
WO2015095410A1
(en)
|
2013-12-17 |
2015-06-25 |
Genentech, Inc. |
Methods of treating cancer using pd-1 axis binding antagonists and an anti-cd20 antibody
|
|
CN112390883A
(zh)
|
2013-12-17 |
2021-02-23 |
基因泰克公司 |
抗cd3抗体及使用方法
|
|
MY189089A
(en)
|
2013-12-17 |
2022-01-25 |
Genentech Inc |
Methods of treating cancers using pd-1 axis binding antagonists and taxanes
|
|
TWI670283B
(zh)
|
2013-12-23 |
2019-09-01 |
美商建南德克公司 |
抗體及使用方法
|
|
CN109535254B
(zh)
|
2013-12-24 |
2022-06-24 |
安斯泰来制药株式会社 |
抗人bdca-2抗体、其生产方法、多核苷酸、表达载体、宿主细胞及医药组合物
|
|
KR102278979B1
(ko)
|
2014-01-03 |
2021-07-19 |
에프. 호프만-라 로슈 아게 |
공유적으로 연결된 헬리카-항-헬리카 항체 접합체 및 그의 용도
|
|
ES2895752T3
(es)
|
2014-01-03 |
2022-02-22 |
Hoffmann La Roche |
Anticuerpos biespecíficos anti-hapteno/anti-receptor de la barrera hematoencefálica, complejos de los mismos y su uso como lanzaderas a través de la barrera hematoencefálica
|
|
CN105873616B
(zh)
|
2014-01-03 |
2020-06-05 |
豪夫迈·罗氏有限公司 |
共价连接的多肽毒素-抗体缀合物
|
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
|
JP6786392B2
(ja)
|
2014-01-15 |
2020-11-18 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
FcRn結合特性が改変され、プロテインA結合特性が保持されているFc領域変異体
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
|
EP3096797A1
(en)
|
2014-01-24 |
2016-11-30 |
F. Hoffmann-La Roche AG |
Methods of using anti-steap1 antibodies and immunoconjugates
|
|
WO2015116852A1
(en)
|
2014-01-29 |
2015-08-06 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating rheumatoid arthritis by administering an il-6r antibody
|
|
EP3102608B1
(en)
|
2014-02-03 |
2019-09-18 |
Bioasis Technologies Inc. |
P97 fusion proteins
|
|
KR20240094017A
(ko)
|
2014-02-08 |
2024-06-24 |
제넨테크, 인크. |
알츠하이머 질환을 치료하는 방법
|
|
MX388168B
(es)
|
2014-02-08 |
2025-03-19 |
Genentech Inc |
Un anticuerpo anti-amiloide beta (a?) monoclonal humanizado para usarse en el tratamiento de enfermedad de alzheimer.
|
|
US9518121B2
(en)
|
2014-02-12 |
2016-12-13 |
Genentech, Inc. |
Anti-Jagged1 antibodies and methods of use
|
|
US20150231236A1
(en)
|
2014-02-14 |
2015-08-20 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating patients with hypercholesterolemia that is not adequately controlled by moderate-dose statin therapy
|
|
EP3107562B1
(en)
|
2014-02-19 |
2019-09-18 |
Bioasis Technologies Inc. |
P97-ids fusion proteins
|
|
WO2015127405A2
(en)
|
2014-02-21 |
2015-08-27 |
Genentech, Inc. |
Anti-il-13/il-17 bispecific antibodies and uses thereof
|
|
IL315136A
(en)
|
2014-02-21 |
2024-10-01 |
Sanofi Biotechnology |
Methods for treating or preventing asthma by administering an il-4rantagonist
|
|
PT3122757T
(pt)
|
2014-02-28 |
2023-11-03 |
Hangzhou Dac Biotech Co Ltd |
Ligantes carregados e as suas utilizações em conjugação
|
|
MX2016011637A
(es)
|
2014-03-14 |
2017-04-13 |
Genentech Inc |
Metodos y composiciones para secrecion de polipeptidos heterologos.
|
|
ES2762640T3
(es)
|
2014-03-21 |
2020-05-25 |
Regeneron Pharma |
Proteínas VL de unión a antígeno que exhiben diferentes características de unión
|
|
US20170107294A1
(en)
|
2014-03-21 |
2017-04-20 |
Nordlandssykehuset Hf |
Anti-cd14 antibodies and uses thereof
|
|
RU2688349C2
(ru)
|
2014-03-21 |
2019-05-21 |
Ф. Хоффманн-Ля Рош Аг |
In vitro прогнозирование времени полужизни антител in vivo
|
|
BR112016021572A2
(pt)
|
2014-03-21 |
2017-10-03 |
Regeneron Pharma |
Métodos para preparar um animal não humano geneticamente modificado e para produzir proteínas de ligação, hibridoma, ácido nucleico, célula, e, proteína de ligação
|
|
EP3122900A1
(en)
|
2014-03-24 |
2017-02-01 |
F. Hoffmann-La Roche AG |
Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
|
|
AU2015241037B2
(en)
|
2014-03-31 |
2020-10-15 |
Genentech, Inc. |
Anti-OX40 antibodies and methods of use
|
|
MX2016012779A
(es)
|
2014-03-31 |
2017-04-27 |
Genentech Inc |
Terapia de combinacion con agentes antiangiogénesis y agonistas de unión a ox40.
|
|
CN113092788A
(zh)
|
2014-04-02 |
2021-07-09 |
豪夫迈·罗氏有限公司 |
检测多特异性抗体轻链错配的方法
|
|
WO2015153912A1
(en)
|
2014-04-03 |
2015-10-08 |
Igm Biosciences, Inc. |
Modified j-chain
|
|
EP3808778A1
(en)
|
2014-04-18 |
2021-04-21 |
Acceleron Pharma Inc. |
Methods for increasing red blood cell levels and treating sickle-cell disease
|
|
WO2015164615A1
(en)
|
2014-04-24 |
2015-10-29 |
University Of Oslo |
Anti-gluten antibodies and uses thereof
|
|
JP6847664B2
(ja)
|
2014-05-01 |
2021-03-24 |
バイオアシス テクノロジーズ インコーポレイテッド |
P97−ポリヌクレオチド複合体
|
|
NO2785538T3
(OSRAM)
*
|
2014-05-07 |
2018-08-04 |
|
|
|
KR20250096864A
(ko)
|
2014-05-19 |
2025-06-27 |
리제너론 파마슈티칼스 인코포레이티드 |
인간 epo를 발현하는 유전자 변형된 비-인간 동물
|
|
BR112016027222A2
(pt)
|
2014-05-22 |
2018-01-30 |
Genentech Inc |
anticorpos isolados, ácido nucleico isolado, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, métodos de tratamento de um indivíduo com um câncer, de inibição da proliferação de uma célula, de detecção de gpc3 humano e de detecção de um câncer
|
|
KR20170005016A
(ko)
|
2014-05-23 |
2017-01-11 |
제넨테크, 인크. |
MiT 바이오마커 및 그의 사용 방법
|
|
US9497945B2
(en)
|
2014-05-30 |
2016-11-22 |
Regeneron Pharmaceuticals, Inc. |
Humanized dipeptidyl peptidase IV (DPP4) animals
|
|
MX385689B
(es)
|
2014-06-06 |
2025-03-18 |
Regeneron Pharma |
Métodos y composiciones para modificar un locus dirigido.
|
|
KR20170010785A
(ko)
|
2014-06-11 |
2017-02-01 |
제넨테크, 인크. |
항-lgr5 항체 및 이의 용도
|
|
CN107135646B
(zh)
|
2014-06-13 |
2022-03-15 |
阿塞勒隆制药公司 |
用于治疗溃疡的方法和组合物
|
|
JP2017517552A
(ja)
|
2014-06-13 |
2017-06-29 |
ジェネンテック, インコーポレイテッド |
抗癌剤耐性の治療及び防止方法
|
|
TWI713453B
(zh)
|
2014-06-23 |
2020-12-21 |
美商健生生物科技公司 |
干擾素α及ω抗體拮抗劑
|
|
US9738897B2
(en)
|
2014-06-23 |
2017-08-22 |
Regeneron Pharmaceuticals, Inc. |
Nuclease-mediated DNA assembly
|
|
WO2015200805A2
(en)
|
2014-06-26 |
2015-12-30 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for targeted genetic modifications and methods of use
|
|
TW201623329A
(zh)
|
2014-06-30 |
2016-07-01 |
亞佛瑞司股份有限公司 |
針對骨調素截斷變異體的疫苗及單株抗體暨其用途
|
|
AU2015286604B2
(en)
|
2014-07-10 |
2019-08-15 |
Hd Immune Gmbh |
Substances and methods for the use in prevention and/or treatment in Huntington's disease
|
|
CN106488775A
(zh)
|
2014-07-11 |
2017-03-08 |
基因泰克公司 |
Notch途径抑制
|
|
JP2017523776A
(ja)
|
2014-07-14 |
2017-08-24 |
ジェネンテック, インコーポレイテッド |
膠芽腫の診断方法及びその治療用組成物
|
|
CA2955294A1
(en)
|
2014-07-16 |
2016-01-21 |
Sanofi Biotechnology |
Methods for treating patients with heterozygous familial hypercholesterolemia (hefh)
|
|
EP3753575A1
(en)
|
2014-07-16 |
2020-12-23 |
Sanofi Biotechnology |
Methods for treating high cardiovascular risk patients with hypercholesterolemia using inhibitors of pcsk9
|
|
CN106661578B
(zh)
|
2014-08-15 |
2020-08-04 |
埃迪恩克斯股份有限公司 |
用于疼痛治疗的寡核苷酸诱饵
|
|
PE20170935A1
(es)
|
2014-09-12 |
2017-07-13 |
Genentech Inc |
Anticuerpos anti-her2 e inmunoconjugados
|
|
CR20170095A
(es)
|
2014-09-12 |
2017-07-19 |
Genentech Inc |
Anticuerpos anti-cll-1 e inmunoconjugados referencias recíprocas con solicitudes relacionadas
|
|
WO2016040724A1
(en)
|
2014-09-12 |
2016-03-17 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
|
CN107001461A
(zh)
|
2014-09-16 |
2017-08-01 |
瑞泽恩制药公司 |
抗胰高血糖素抗体及其使用方法
|
|
KR20170055521A
(ko)
|
2014-09-17 |
2017-05-19 |
제넨테크, 인크. |
항-her2 항체를 포함하는 면역콘주게이트
|
|
RU2017113134A
(ru)
|
2014-09-19 |
2018-10-19 |
Регенерон Фармасьютикалз, Инк. |
Химерные антигенные рецепторы
|
|
EP3262071B8
(en)
|
2014-09-23 |
2022-05-18 |
F. Hoffmann-La Roche AG |
Method of using anti-cd79b immunoconjugates
|
|
MX2017003841A
(es)
|
2014-09-23 |
2018-02-23 |
Regeneron Pharma |
Anticuerpos anti-il-25 y usos de los mismos.
|
|
EP3561052A1
(en)
|
2014-10-15 |
2019-10-30 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for generating or maintaining pluripotent cells
|
|
CN107074938A
(zh)
|
2014-10-16 |
2017-08-18 |
豪夫迈·罗氏有限公司 |
抗‑α‑突触核蛋白抗体和使用方法
|
|
EP3209697A4
(en)
|
2014-10-23 |
2018-05-30 |
La Trobe University |
Fn14-binding proteins and uses thereof
|
|
EP3223865A4
(en)
|
2014-10-31 |
2018-10-03 |
Jounce Therapeutics, Inc. |
Methods of treating conditions with antibodies that bind b7-h4
|
|
SG11201703448QA
(en)
|
2014-11-03 |
2017-05-30 |
Genentech Inc |
Assays for detecting t cell immune subsets and methods of use thereof
|
|
RU2017119231A
(ru)
|
2014-11-03 |
2018-12-06 |
Дженентек, Инк. |
Способы и биомаркеры для прогнозирования эффективности и оценки лечения агонистом ох40
|
|
PT3215528T
(pt)
|
2014-11-06 |
2019-10-11 |
Hoffmann La Roche |
Variantes da região fc com ligação modificada ao fcrn e métodos de utilização
|
|
BR112017006591A2
(pt)
|
2014-11-06 |
2018-01-16 |
Hoffmann La Roche |
polipeptídeo heterodimérico, formulação farmacêutica e uso de um polipeptídeo heterodimérico
|
|
WO2016073282A1
(en)
|
2014-11-06 |
2016-05-12 |
Genentech, Inc. |
Combination therapy comprising ox40 binding agonists and tigit inhibitors
|
|
JP2018500882A
(ja)
|
2014-11-10 |
2018-01-18 |
ジェネンテック, インコーポレイテッド |
腎症の動物モデルおよびそれを治療するための薬剤
|
|
CA2960297A1
(en)
|
2014-11-10 |
2016-05-19 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
|
MX2017006286A
(es)
|
2014-11-14 |
2018-01-23 |
Sanofi Biotechnology |
Metodos para tratar sinusitis cronica con polipos nasales por administracion de un antagonista de il-4r.
|
|
WO2016077789A1
(en)
|
2014-11-14 |
2016-05-19 |
The Usa, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to ebola virus glycoprotein and their use
|
|
DK3218396T3
(da)
|
2014-11-14 |
2023-03-06 |
Regeneron Pharma |
Fremgangsmåde til fremstilling af højaffinitets antistoffer
|
|
SG10201807625PA
(en)
|
2014-11-17 |
2018-10-30 |
Genentech Inc |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
|
CN107001473B
(zh)
|
2014-11-19 |
2021-07-09 |
豪夫迈·罗氏有限公司 |
抗-运铁蛋白受体抗体及使用方法
|
|
JP6859259B2
(ja)
|
2014-11-19 |
2021-04-14 |
ジェネンテック, インコーポレイテッド |
BACElに対する抗体及び神経疾患免疫療法のためのその使用
|
|
JP6993228B2
(ja)
|
2014-11-19 |
2022-03-03 |
ジェネンテック, インコーポレイテッド |
抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法
|
|
ES2926673T3
(es)
|
2014-11-20 |
2022-10-27 |
Hoffmann La Roche |
Politerapia de moléculas de unión a antígeno biespecíficas activadoras de linfocitos T y antagonistas de la unión al eje de PD-1
|
|
ES2731437T3
(es)
|
2014-11-21 |
2019-11-15 |
Regeneron Pharma |
Métodos y composiciones para la modificación genética dirigida mediante el uso de pares de ARN guías
|
|
DK3223605T3
(da)
|
2014-11-24 |
2020-11-16 |
Regeneron Pharma |
Ikke-humane dyr, der eksprimerer humaniseret cd3-kompleks
|
|
JP6554280B2
(ja)
*
|
2014-11-28 |
2019-07-31 |
株式会社デンソーテン |
データ処理装置、画像処理方法、及び、プログラム
|
|
MA41119A
(fr)
|
2014-12-03 |
2017-10-10 |
Acceleron Pharma Inc |
Méthodes de traitement de syndromes myélodysplasiques et d'anémie sidéroblastique
|
|
SG11201704449VA
(en)
|
2014-12-05 |
2017-06-29 |
Genentech Inc |
ANTI-CD79b ANTIBODIES AND METHODS OF USE
|
|
CA2966365A1
(en)
|
2014-12-10 |
2016-06-16 |
Genentech, Inc. |
Blood brain barrier receptor antibodies and methods of use
|
|
MY181199A
(en)
|
2014-12-19 |
2020-12-21 |
Chugai Pharmaceutical Co Ltd |
Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
|
|
TWI617580B
(zh)
|
2014-12-19 |
2018-03-11 |
中外製藥股份有限公司 |
抗c5抗體及使用方法
|
|
US10940212B2
(en)
|
2014-12-19 |
2021-03-09 |
Monash University |
IL-21 agonist antibodies and methods of treatment using same
|
|
MX388784B
(es)
|
2014-12-19 |
2025-03-20 |
Regeneron Pharma |
Métodos y composiciones para la modificación genética dirigida a través de direccionamiento múltiple de una sola etapa.
|
|
TWI702229B
(zh)
|
2014-12-19 |
2020-08-21 |
美商再生元醫藥公司 |
流行性感冒病毒血球凝集素之人類抗體
|
|
US20160200815A1
(en)
|
2015-01-05 |
2016-07-14 |
Jounce Therapeutics, Inc. |
Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof
|
|
WO2016117346A1
(en)
|
2015-01-22 |
2016-07-28 |
Chugai Seiyaku Kabushiki Kaisha |
A combination of two or more anti-c5 antibodies and methods of use
|
|
TWI710573B
(zh)
|
2015-01-26 |
2020-11-21 |
美商再生元醫藥公司 |
抗伊波拉病毒醣蛋白之人類抗體
|
|
CN107108729A
(zh)
|
2015-02-05 |
2017-08-29 |
中外制药株式会社 |
包含离子浓度依赖性的抗原结合结构域的抗体,fc区变体,il‑8‑结合抗体,及其应用
|
|
CN107847584B
(zh)
|
2015-02-09 |
2022-01-25 |
纪念斯隆凯特琳癌症中心 |
具有人a33抗原和dota金属复合物亲和力的多特异性抗体及其用途
|
|
WO2016131058A1
(en)
|
2015-02-13 |
2016-08-18 |
Biommune Technologies Inc. |
Antibodies to l-type voltage gated channels and related methods
|
|
EA039310B1
(ru)
|
2015-02-26 |
2022-01-12 |
Санофи Байотекнолоджи |
Способы снижения сердечно-сосудистого риска
|
|
TWI719967B
(zh)
|
2015-03-09 |
2021-03-01 |
美商艾澤西公司 |
結合至flt3蛋白之抗體藥物結合物(adc)
|
|
JP2018511797A
(ja)
|
2015-03-16 |
2018-04-26 |
ジェネンテック, インコーポレイテッド |
IL−13の検出方法及び定量方法並びにTh2関連疾患の診断及び治療における使用
|
|
IL274285B
(en)
|
2015-03-16 |
2022-07-01 |
Regeneron Pharma |
Non-human animal exhibiting diminished upper and lower motor neuron function and sensory perception
|
|
WO2016146833A1
(en)
|
2015-03-19 |
2016-09-22 |
F. Hoffmann-La Roche Ag |
Biomarkers for nad(+)-diphthamide adp ribosyltransferase resistance
|
|
EP3271403A1
(en)
|
2015-03-19 |
2018-01-24 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals that select for light chain variable regions that bind antigen
|
|
HRP20200583T1
(hr)
|
2015-03-20 |
2020-07-10 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Protutijela koja neutraliziraju gp120 i njihova upotreba
|
|
HUE049938T2
(hu)
|
2015-03-23 |
2020-11-30 |
Jounce Therapeutics Inc |
Icos elleni antitestek
|
|
WO2016160615A1
(en)
|
2015-03-27 |
2016-10-06 |
Regeneron Pharmaceuticals, Inc. |
Maytansinoid derivatives, conjugates thereof, and methods of use
|
|
KR20240132525A
(ko)
|
2015-04-06 |
2024-09-03 |
리제너론 파아마슈티컬스, 인크. |
비인간 동물에서의 인간화 t 세포 매개 면역반응
|
|
MA41919A
(fr)
|
2015-04-06 |
2018-02-13 |
Acceleron Pharma Inc |
Hétéromultimères alk4:actriib et leurs utilisations
|
|
MA53400A
(fr)
|
2015-04-06 |
2021-08-04 |
Acceleron Pharma Inc |
Hétéromultimères alk7: actriib et leurs utilisations
|
|
EP3280736A1
(en)
|
2015-04-07 |
2018-02-14 |
F. Hoffmann-La Roche AG |
Antigen binding complex having agonistic activity and methods of use
|
|
PL3280441T3
(pl)
|
2015-04-07 |
2022-02-21 |
Alector Llc |
Przeciwciała przeciwko sortilinie i sposoby ich stosowania
|
|
CN107896479B
(zh)
|
2015-04-13 |
2021-07-13 |
再生元制药公司 |
人源化SIRPα-IL15敲入小鼠及其使用方法
|
|
CN115932273A
(zh)
|
2015-04-24 |
2023-04-07 |
豪夫迈·罗氏有限公司 |
鉴定包含结合多肽的细菌的方法
|
|
EP3778640A1
(en)
|
2015-05-01 |
2021-02-17 |
Genentech, Inc. |
Masked anti-cd3 antibodies and methods of use
|
|
WO2016179194A1
(en)
|
2015-05-04 |
2016-11-10 |
Jounce Therapeutics, Inc. |
Lilra3 and method of using the same
|
|
EP4450524A3
(en)
|
2015-05-11 |
2025-05-14 |
F. Hoffmann-La Roche AG |
Compositions and methods of treating lupus nephritis
|
|
MX2017014381A
(es)
|
2015-05-12 |
2018-03-02 |
Genentech Inc |
Metodos terapeuticos y diagnosticos para cancer.
|
|
US10395759B2
(en)
|
2015-05-18 |
2019-08-27 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for copy number variant detection
|
|
JP6913030B2
(ja)
|
2015-05-18 |
2021-08-04 |
アジェンシス,インコーポレイテッド |
Axlタンパク質に結合する抗体
|
|
WO2016187354A1
(en)
|
2015-05-18 |
2016-11-24 |
Agensys, Inc. |
Antibodies that bind to axl proteins
|
|
JP7144935B2
(ja)
|
2015-05-29 |
2022-09-30 |
ジェネンテック, インコーポレイテッド |
癌のための治療方法及び診断方法
|
|
CN107771182A
(zh)
|
2015-05-29 |
2018-03-06 |
豪夫迈·罗氏有限公司 |
人源化抗埃博拉病毒糖蛋白抗体和使用方法
|
|
KR102377189B1
(ko)
|
2015-05-29 |
2022-03-22 |
리제너론 파마슈티칼스 인코포레이티드 |
C9orf72 유전자좌에서 파괴를 갖는 비-인간 동물
|
|
JP2018516933A
(ja)
|
2015-06-02 |
2018-06-28 |
ジェネンテック, インコーポレイテッド |
抗il−34抗体を使用して神経学的疾患を治療するための組成物及び方法
|
|
WO2016196975A1
(en)
|
2015-06-03 |
2016-12-08 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
|
PL3303386T3
(pl)
|
2015-06-05 |
2025-03-03 |
Genentech, Inc. |
Przeciwciała anty-tau i sposoby zastosowania
|
|
KR20180025888A
(ko)
|
2015-06-08 |
2018-03-09 |
제넨테크, 인크. |
항-ox40 항체 및 pd-1 축 결합 길항제를 사용하여 암을 치료하는 방법
|
|
EP3303399A1
(en)
|
2015-06-08 |
2018-04-11 |
H. Hoffnabb-La Roche Ag |
Methods of treating cancer using anti-ox40 antibodies
|
|
KR20180033502A
(ko)
|
2015-06-12 |
2018-04-03 |
알렉터 엘엘씨 |
항-cd33 항체 및 그의 사용 방법
|
|
WO2016201389A2
(en)
|
2015-06-12 |
2016-12-15 |
Alector Llc |
Anti-cd33 antibodies and methods of use thereof
|
|
EP3307780A1
(en)
|
2015-06-15 |
2018-04-18 |
Genentech, Inc. |
Antibodies and immunoconjugates
|
|
WO2016204966A1
(en)
|
2015-06-16 |
2016-12-22 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
|
CN107847568B
(zh)
|
2015-06-16 |
2022-12-20 |
豪夫迈·罗氏有限公司 |
抗cll-1抗体和使用方法
|
|
EP3310814B1
(en)
|
2015-06-16 |
2023-08-02 |
F. Hoffmann-La Roche AG |
Humanized and affinity matured antibodies to fcrh5 and methods of use
|
|
CN116327953A
(zh)
|
2015-06-17 |
2023-06-27 |
豪夫迈·罗氏有限公司 |
使用pd-1轴结合拮抗剂和紫杉烷治疗局部晚期或转移性乳腺癌的方法
|
|
KR20180012859A
(ko)
|
2015-06-17 |
2018-02-06 |
제넨테크, 인크. |
항-her2 항체 및 이용 방법
|
|
IL302486A
(en)
|
2015-06-24 |
2023-06-01 |
Hoffmann La Roche |
Antibodies against the transnephrine receptor with adapted affinity
|
|
EP3313885A1
(en)
|
2015-06-29 |
2018-05-02 |
H. Hoffnabb-La Roche Ag |
Type ii anti-cd20 antibody for use in organ transplantation
|
|
CN108449940B
(zh)
|
2015-07-12 |
2021-06-08 |
杭州多禧生物科技有限公司 |
与细胞结合分子的共轭偶联的桥连接体
|
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
|
EP3331550B1
(en)
|
2015-08-04 |
2022-11-02 |
Acceleron Pharma Inc. |
Composition for treating myeloproliferative disorders
|
|
US10669343B2
(en)
|
2015-08-05 |
2020-06-02 |
Janssen Biotech, Inc. |
Anti-CD154 antibodies and methods of using them
|
|
TW201713690A
(zh)
|
2015-08-07 |
2017-04-16 |
再生元醫藥公司 |
抗angptl8抗體及其用途
|
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
|
US10772956B2
(en)
|
2015-08-18 |
2020-09-15 |
Regeneron Pharmaceuticals, Inc. |
Methods for reducing or eliminating the need for lipoprotein apheresis in patients with hyperlipidemia by administering alirocumab
|
|
RU2018110364A
(ru)
|
2015-08-24 |
2019-09-26 |
Трианни, Инк. |
Усовершенствованное продуцирование иммуноглобулинов
|
|
US9862760B2
(en)
|
2015-09-16 |
2018-01-09 |
Novartis Ag |
Polyomavirus neutralizing antibodies
|
|
PH12018500386B1
(en)
|
2015-09-18 |
2024-01-05 |
Chugai Pharmaceutical Co Ltd |
Il-8-binding antibodies and uses thereof
|
|
CN116987187A
(zh)
|
2015-09-23 |
2023-11-03 |
豪夫迈·罗氏有限公司 |
抗-vegf抗体的优化的变体
|
|
CA2999917A1
(en)
|
2015-09-24 |
2017-03-30 |
Abvitro Llc |
Hiv antibody compositions and methods of use
|
|
MY186016A
(en)
|
2015-09-25 |
2021-06-14 |
Genentech Inc |
Anti-tigit antibodies and methods of use
|
|
CN108368510B
(zh)
|
2015-09-30 |
2023-09-01 |
詹森生物科技公司 |
特异性结合人cd40的激动性抗体和使用方法
|
|
HK1252791A1
(zh)
|
2015-09-30 |
2019-06-06 |
Igm Biosciences, Inc. |
具有经修饰的j链的结合分子
|
|
DK3356401T3
(da)
|
2015-09-30 |
2020-09-07 |
Igm Biosciences Inc |
Bindingsmolekyler med modificeret j-kæde
|
|
CN114057885A
(zh)
|
2015-10-02 |
2022-02-18 |
豪夫迈·罗氏有限公司 |
双特异性抗人cd20/人转铁蛋白受体抗体及使用方法
|
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
|
RU2746409C1
(ru)
|
2015-10-02 |
2021-04-13 |
Ф. Хоффманн-Ля Рош Аг |
Антитела к pd1 и способы их применения
|
|
AR106189A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
|
|
TWI756187B
(zh)
|
2015-10-09 |
2022-03-01 |
美商再生元醫藥公司 |
抗lag3抗體及其用途
|
|
TWI752920B
(zh)
|
2015-10-12 |
2022-01-21 |
美商再生元醫藥公司 |
活化瘦素受體的抗原結合蛋白
|
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
|
MA45326A
(fr)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
|
|
CA2998208A1
(en)
|
2015-10-22 |
2017-04-27 |
Jounce Therapeutics, Inc. |
Gene signatures for determining icos expression
|
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
|
US10407510B2
(en)
|
2015-10-30 |
2019-09-10 |
Genentech, Inc. |
Anti-factor D antibodies and conjugates
|
|
ES2870141T3
(es)
|
2015-10-30 |
2021-10-26 |
Hoffmann La Roche |
Anticuerpos anti-HtrA1 y procedimientos de uso de los mismos
|
|
MY198562A
(en)
|
2015-11-03 |
2023-09-05 |
Janssen Biotech Inc |
Antibodies specifically binding pd-1 and their uses
|
|
WO2017079591A2
(en)
|
2015-11-04 |
2017-05-11 |
Acceleron Pharma Inc. |
Methods for increasing red blood cell levels and treating ineffective erythropoiesis
|
|
EP3371217B1
(en)
|
2015-11-08 |
2025-06-11 |
F. Hoffmann-La Roche AG |
Methods of screening for multispecific antibodies
|
|
US10550170B2
(en)
|
2015-11-23 |
2020-02-04 |
Acceleron Pharma Inc. |
Methods for treating vascular eye disorders with actrii antagonists
|
|
BR112018010766A8
(pt)
|
2015-11-27 |
2019-02-26 |
Csl Ltd |
proteínas de ligação ao cd131 e usos das mesmas
|
|
EP3384030A4
(en)
|
2015-12-03 |
2019-07-03 |
Trianni, Inc. |
IMPROVED IMMUNOGLULINIVITY
|
|
KR102850929B1
(ko)
|
2015-12-09 |
2025-08-27 |
에프. 호프만-라 로슈 아게 |
항-약물 항체의 형성을 감소시키기 위한 ii형 항-cd20 항체
|
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
|
BR112018012344A2
(pt)
|
2015-12-17 |
2018-12-04 |
Janssen Biotech Inc |
anticorpos que se ligam especificamente a hla-dr e seus usos
|
|
WO2017104783A1
(en)
|
2015-12-18 |
2017-06-22 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
|
|
IL259256B2
(en)
|
2015-12-18 |
2023-02-01 |
Chugai Pharmaceutical Co Ltd |
Anti-c5 antibodies and methods of use
|
|
HRP20231156T1
(hr)
|
2015-12-22 |
2024-01-05 |
Regeneron Pharmaceuticals, Inc. |
Kombinacija anti-pd-1 antitijela i bispecifičnih anti-cd20/anti-cd3 antitijela za liječenje raka
|
|
KR20180097615A
(ko)
|
2016-01-08 |
2018-08-31 |
에프. 호프만-라 로슈 아게 |
Pd-1 축 결합 길항물질 및 항-cea/항-cd3 이중특이성 항체를 사용하는 cea-양성 암의 치료 방법
|
|
IL302725A
(en)
|
2016-01-13 |
2023-07-01 |
Regeneron Pharma |
Rodents having an engineered heavy chain diversity region
|
|
CN114019170A
(zh)
|
2016-01-20 |
2022-02-08 |
基因泰克公司 |
用于阿尔茨海默氏病的高剂量治疗
|
|
MX390630B
(es)
|
2016-01-25 |
2025-03-21 |
Regeneron Pharma |
Derivados de maitansinoide, conjugados de los mismos y metodos de uso.
|
|
WO2017136734A1
(en)
|
2016-02-04 |
2017-08-10 |
Trianni, Inc. |
Enhanced production of immunoglobulins
|
|
AU2017218149B2
(en)
|
2016-02-12 |
2020-09-03 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for detection of abnormal karyotypes
|
|
SG11201806427WA
(en)
*
|
2016-02-16 |
2018-08-30 |
Regeneron Pharma |
Non-human animals having a mutant kynureninase gene
|
|
PT3416684T
(pt)
|
2016-02-17 |
2023-07-04 |
Regeneron Pharma |
Métodos para tratamento ou prevenção da aterosclerose por administração de um inibidor da angptl3
|
|
KR102500659B1
(ko)
|
2016-02-29 |
2023-02-16 |
제넨테크, 인크. |
암에 대한 치료 및 진단 방법
|
|
CN109069868B
(zh)
|
2016-03-03 |
2023-06-06 |
瑞泽恩制药公司 |
通过施用与angptl3抑制剂组合的pcsk9抑制剂治疗高脂血症患者的方法
|
|
WO2017159699A1
(en)
|
2016-03-15 |
2017-09-21 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of treating cancers using pd-1 axis binding antagonists and anti-gpc3 antibodies
|
|
US20170315132A1
(en)
|
2016-03-25 |
2017-11-02 |
Genentech, Inc. |
Multiplexed total antibody and antibody-conjugated drug quantification assay
|
|
JP2019515369A
(ja)
|
2016-03-29 |
2019-06-06 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
遺伝的バリアント−表現型解析システムおよび使用方法
|
|
EP3440194A1
(en)
*
|
2016-04-04 |
2019-02-13 |
ETH Zurich |
Mammalian cell line for protein production and library generation
|
|
WO2017177013A1
(en)
|
2016-04-06 |
2017-10-12 |
Acceleron Pharma Inc. |
Alk7 antagonists and uses thereof
|
|
EP3228630A1
(en)
|
2016-04-07 |
2017-10-11 |
IMBA-Institut für Molekulare Biotechnologie GmbH |
Combination of an apelin antagonist and an angiogenesis inhibitor for the treatment of cancer
|
|
AU2017248356A1
(en)
|
2016-04-08 |
2018-10-25 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating hyperlipidemia with an ANGPTL8 inhibitor and an ANGPTL3 inhibitor
|
|
WO2017180864A1
(en)
|
2016-04-14 |
2017-10-19 |
Genentech, Inc. |
Anti-rspo3 antibodies and methods of use
|
|
JP2019515670A
(ja)
|
2016-04-15 |
2019-06-13 |
ジェネンテック, インコーポレイテッド |
がんをモニタリングし治療するための方法
|
|
KR20190003958A
(ko)
|
2016-04-15 |
2019-01-10 |
제넨테크, 인크. |
암의 치료 및 모니터링 방법
|
|
JP7201437B2
(ja)
|
2016-04-28 |
2023-01-10 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
家族性高コレステロール血症を有する患者を処置するための方法
|
|
SG11201809620UA
(en)
|
2016-05-02 |
2018-11-29 |
Hoffmann La Roche |
The contorsbody - a single chain target binder
|
|
JP7089483B2
(ja)
|
2016-05-11 |
2022-06-22 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
修飾された抗テネイシン抗体及び使用方法
|
|
TWI755395B
(zh)
|
2016-05-13 |
2022-02-21 |
美商再生元醫藥公司 |
抗-pd-1抗體與輻射治療癌症之組合
|
|
MX2018014172A
(es)
|
2016-05-20 |
2019-08-22 |
Regeneron Pharma |
Métodos para romper la tolerancia inmunológica usando múltiples arn guías.
|
|
ES2858151T3
(es)
|
2016-05-20 |
2021-09-29 |
Hoffmann La Roche |
Conjugados de PROTAC-anticuerpo y procedimientos de uso
|
|
US20170370906A1
(en)
|
2016-05-27 |
2017-12-28 |
Genentech, Inc. |
Bioanalytical analysis of site-specific antibody drug conjugates
|
|
CN110603266A
(zh)
|
2016-06-02 |
2019-12-20 |
豪夫迈·罗氏有限公司 |
用于治疗癌症的ii型抗cd20抗体和抗cd20/cd3双特异性抗体
|
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
|
CN109640644B
(zh)
|
2016-06-03 |
2021-10-26 |
瑞泽恩制药公司 |
表达外源末端脱氧核苷酸转移酶的非人动物
|
|
WO2017214089A1
(en)
|
2016-06-06 |
2017-12-14 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals expressing antibodies with human lambda light chains
|
|
EP3464280B1
(en)
|
2016-06-06 |
2021-10-06 |
F. Hoffmann-La Roche AG |
Silvestrol antibody-drug conjugates and methods of use
|
|
KR102187751B1
(ko)
|
2016-06-06 |
2020-12-08 |
에프. 호프만-라 로슈 아게 |
눈 잔류가 증가된 안과학용 융합 단백질
|
|
GB201610162D0
(en)
|
2016-06-10 |
2016-07-27 |
Imp Innovations Ltd And Inst Pasteur |
Methods
|
|
MY196006A
(en)
|
2016-06-14 |
2023-03-06 |
Regeneron Pharma |
Anti-C5 Antibodies and Uses Thereof
|
|
EA201990017A1
(ru)
|
2016-06-17 |
2019-07-31 |
Чугаи Сейяку Кабусики Кайся |
Антитела к миостатину и способы их применения
|
|
CN109563160B
(zh)
|
2016-06-24 |
2023-02-28 |
豪夫迈·罗氏有限公司 |
抗聚泛素多特异性抗体
|
|
MX2018016330A
(es)
|
2016-06-27 |
2020-02-17 |
Univ California |
Combinaciones para tratamiento del cáncer.
|
|
EP3478717B1
(en)
|
2016-07-04 |
2022-01-05 |
F. Hoffmann-La Roche AG |
Novel antibody format
|
|
SI3496739T1
(sl)
|
2016-07-15 |
2021-06-30 |
Acceleron Pharma Inc. |
Sestave, ki zajemajo polipeptide actriia, za uporabo pri zdravljenju pljučne hipertenzije
|
|
TW201815821A
(zh)
|
2016-07-18 |
2018-05-01 |
美商再生元醫藥公司 |
抗茲卡病毒抗體及使用方法
|
|
WO2018014260A1
(en)
|
2016-07-20 |
2018-01-25 |
Nanjing Legend Biotech Co., Ltd. |
Multispecific antigen binding proteins and methods of use thereof
|
|
AU2017302282B2
(en)
|
2016-07-27 |
2024-07-25 |
Acceleron Pharma Inc. |
Methods and compositions for treating myelofibrosis
|
|
US10548302B2
(en)
|
2016-07-29 |
2020-02-04 |
Regeneron Pharmaceuticals, Inc. |
Fibrillin-1 mutations for modeling neonatal progeroid syndrome with congenital lipodystrophy
|
|
MX2018015721A
(es)
|
2016-07-29 |
2019-05-27 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos biespecificos que exhiben actividad de funcion de cofactor fviii alternativa mejorada.
|
|
JP6527643B2
(ja)
|
2016-08-05 |
2019-06-05 |
中外製薬株式会社 |
Il−8関連疾患の治療用又は予防用組成物
|
|
EP3494139B1
(en)
|
2016-08-05 |
2022-01-12 |
F. Hoffmann-La Roche AG |
Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
|
|
JP7250674B2
(ja)
|
2016-08-08 |
2023-04-03 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
がんの治療及び診断方法
|
|
EP3282019A1
(en)
|
2016-08-09 |
2018-02-14 |
Medizinische Universität Wien |
Genotyping and treatment of cancer, in particular chronic lymphocytic leukemia
|
|
WO2018031662A1
(en)
|
2016-08-11 |
2018-02-15 |
Genentech, Inc. |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|
|
CA3033665A1
(en)
|
2016-08-12 |
2018-02-15 |
Janssen Biotech, Inc. |
Fc engineered anti-tnfr superfamily member antibodies having enhanced agonistic activity and methods of using them
|
|
SG11201900746RA
(en)
|
2016-08-12 |
2019-02-27 |
Janssen Biotech Inc |
Engineered antibodies and other fc-domain containing molecules with enhanced agonism and effector functions
|
|
WO2018039131A1
(en)
|
2016-08-22 |
2018-03-01 |
Protiva Biotherapeutics, Inc. |
Anti-pd-1 antibodies, or fragments thereof, for treating hepatitis b
|
|
MA46046A
(fr)
|
2016-08-29 |
2019-07-03 |
Regeneron Pharma |
Anticorps anti-gremlin-1 (grem1) et procédés d'utilisation de ces anticorps dans le traitement de l'hypertension artérielle pulmonaire
|
|
SG10201607778XA
(en)
|
2016-09-16 |
2018-04-27 |
Chugai Pharmaceutical Co Ltd |
Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
|
|
CN116731197A
(zh)
|
2016-09-19 |
2023-09-12 |
豪夫迈·罗氏有限公司 |
基于补体因子的亲和层析
|
|
CA3034105A1
(en)
|
2016-09-23 |
2018-03-29 |
Csl Limited |
Coagulation factor binding proteins and uses thereof
|
|
RU2752785C2
(ru)
|
2016-09-23 |
2021-08-04 |
Дженентек, Инк. |
Применение антагонистов il-13 для лечения атопического дерматита
|
|
EP3518667B1
(en)
|
2016-09-30 |
2024-10-30 |
Regeneron Pharmaceuticals, Inc. |
Rodents having a hexanucleotide repeat expansion in a c9orf72 locus
|
|
CN110198743B
(zh)
|
2016-10-05 |
2023-07-18 |
艾科赛扬制药股份有限公司 |
用于治疗肾脏疾病的组合物和方法
|
|
CN110139674B
(zh)
|
2016-10-05 |
2023-05-16 |
豪夫迈·罗氏有限公司 |
制备抗体药物缀合物的方法
|
|
JP7579056B2
(ja)
|
2016-10-06 |
2024-11-07 |
ジェネンテック, インコーポレイテッド |
がんのための治療方法及び診断方法
|
|
WO2018068201A1
(en)
|
2016-10-11 |
2018-04-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against ctla-4
|
|
WO2018075954A2
(en)
|
2016-10-21 |
2018-04-26 |
Adimab, Llc |
Anti-respiratory syncytial virus antibodies, and methods of their generation and use
|
|
CN110035771B
(zh)
|
2016-10-21 |
2024-03-08 |
阿迪马布有限责任公司 |
抗呼吸道合胞病毒抗体及其产生和使用方法
|
|
CA3040893A1
(en)
|
2016-10-21 |
2018-04-26 |
Adimab, Llc |
Anti-respiratory syncytial virus antibodies, and methods of their generation and use
|
|
WO2018081648A2
(en)
|
2016-10-29 |
2018-05-03 |
Genentech, Inc. |
Anti-mic antibidies and methods of use
|
|
CN109906272A
(zh)
*
|
2016-10-31 |
2019-06-18 |
国立大学法人鸟取大学 |
产生人抗体的非人动物和使用该非人动物的人抗体制作方法
|
|
BR112019008494A2
(pt)
|
2016-11-02 |
2019-07-09 |
Jounce Therapeutics Inc |
anticorpos para pd-1 e usos dos mesmos
|
|
CA3038720A1
(en)
|
2016-11-04 |
2018-07-12 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals having an engineered immunoglobulin lambda light chain locus
|
|
MY199937A
(en)
|
2016-11-08 |
2023-11-29 |
Regeneron Pharma |
Steroids and protein-conjugates thereof
|
|
CN110099682B
(zh)
|
2016-11-14 |
2023-03-31 |
杭州多禧生物科技有限公司 |
偶联连接体,含有此连接体的细胞结合分子-药物偶联物及其制备和应用
|
|
JP7133551B2
(ja)
|
2016-11-17 |
2022-09-08 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
抗angptl8抗体を用いて肥満を処置する方法
|
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
|
WO2018091720A1
(en)
|
2016-11-21 |
2018-05-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the prophylactic treatment of metastases
|
|
MY200701A
(en)
|
2016-11-29 |
2024-01-11 |
Regeneron Pharma |
Method of averting opioid addiction
|
|
KR102480773B1
(ko)
|
2016-11-30 |
2022-12-23 |
크로다 인터내셔날 피엘씨 |
수성 결합제 시스템, 코팅 조성물 및 코팅
|
|
CA3045294A1
(en)
|
2016-12-07 |
2018-06-14 |
Genentech, Inc. |
Anti-tau antibodies and methods of use
|
|
TWI787219B
(zh)
|
2016-12-07 |
2022-12-21 |
美商建南德克公司 |
抗-tau抗體及使用方法
|
|
CA3046432A1
(en)
|
2016-12-13 |
2018-06-21 |
Astellas Pharma Inc. |
Anti-human cd73 antibody
|
|
CN110088292A
(zh)
|
2016-12-21 |
2019-08-02 |
豪夫迈·罗氏有限公司 |
用于体外糖工程化抗体的方法
|
|
KR102390246B1
(ko)
|
2016-12-21 |
2022-04-22 |
에프. 호프만-라 로슈 아게 |
항체의 시험관내 글리코조작에 있어서의 효소의 재사용
|
|
WO2018114877A1
(en)
|
2016-12-21 |
2018-06-28 |
F. Hoffmann-La Roche Ag |
In vitro glycoengineering of antibodies
|
|
WO2018118713A1
(en)
|
2016-12-22 |
2018-06-28 |
Regeneron Pharmaceuticals, Inc. |
Method of treating an allergy with allergen-specific monoclonal antibodies
|
|
JP7007734B2
(ja)
*
|
2016-12-27 |
2022-02-10 |
国立大学法人群馬大学 |
条件付きノックアウト動物の製造方法
|
|
TW202311284A
(zh)
|
2017-01-03 |
2023-03-16 |
美商再生元醫藥公司 |
抗金黃色葡萄球菌溶血素a毒素之人類抗體
|
|
CN118140872A
(zh)
|
2017-01-19 |
2024-06-07 |
欧莫诺艾比公司 |
来自具有多个重链免疫球蛋白基因座的转基因啮齿类动物的人抗体
|
|
RU2019126483A
(ru)
|
2017-01-23 |
2021-02-24 |
Ридженерон Фармасьютикалз, Инк. |
Варианты 17-бета-гидроксистероиддегидрогеназы 13 (hsd17b13) и их применение
|
|
US10713373B2
(en)
*
|
2017-02-09 |
2020-07-14 |
Lifesite, Inc. |
Computing system with information storage mechanism and method of operation thereof
|
|
CN110650974B
(zh)
|
2017-02-10 |
2024-04-19 |
瑞泽恩制药公司 |
用于免疫-pet成像的放射性标记的抗-lag3抗体
|
|
UA126574C2
(uk)
|
2017-02-10 |
2022-11-02 |
Дженентек, Інк. |
Антитіло проти триптази, його композиція та застосування
|
|
US11021535B2
(en)
|
2017-02-10 |
2021-06-01 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
|
EP3589754B1
(en)
|
2017-03-01 |
2023-06-28 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for cancer
|
|
TWI839327B
(zh)
|
2017-03-22 |
2024-04-21 |
美商建南德克公司 |
用於治療眼部病症之最佳化之抗體組合物
|
|
ES2955852T3
(es)
|
2017-04-03 |
2023-12-07 |
Hoffmann La Roche |
Anticuerpos de unión a STEAP-1
|
|
RU2761377C2
(ru)
|
2017-04-03 |
2021-12-07 |
Ф. Хоффманн-Ля Рош Аг |
Иммуноконъюгаты антитела к pd-1 с мутантом il-2 или с il-15
|
|
WO2018184965A1
(en)
|
2017-04-03 |
2018-10-11 |
F. Hoffmann-La Roche Ag |
Immunoconjugates of il-2 with an anti-pd-1 and tim-3 bispecific antibody
|
|
BR112019018779A2
(pt)
|
2017-04-05 |
2020-05-05 |
Hoffmann La Roche |
anticorpos isolados, ácido nucleico isolado, célula hospedeira, método para tratar um indivíduo tendo câncer e para produzir um anticorpo, formulação farmacêutica e uso do anticorpo
|
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
JP7679175B2
(ja)
|
2017-04-20 |
2025-05-19 |
エータイアー ファーマ, インコーポレイテッド |
肺の炎症を治療するための組成物および方法
|
|
CR20190480A
(es)
|
2017-04-21 |
2019-11-20 |
Genentech Inc |
Uso de antagonistas de klk5 para el tratamiento de una enfermedad
|
|
KR102769634B1
(ko)
|
2017-04-27 |
2025-02-19 |
테사로, 인코포레이티드 |
림프구 활성화 유전자-3 (lag-3)에 대한 항체 작용제 및 그의 용도
|
|
WO2018213097A1
(en)
|
2017-05-15 |
2018-11-22 |
University Of Rochester |
Broadly neutralizing anti-influenza monoclonal antibody and uses thereof
|
|
KR20200007905A
(ko)
|
2017-05-18 |
2020-01-22 |
리제너론 파마슈티칼스 인코포레이티드 |
사이클로덱스트린 단백질 약물 접합체
|
|
IL298034B2
(en)
|
2017-06-01 |
2024-05-01 |
Regeneron Pharma |
Antibodies against BET V 1 and methods of using them
|
|
AU2018281045A1
(en)
|
2017-06-05 |
2019-12-12 |
Janssen Biotech, Inc. |
Engineered multispecific antibodies and other multimeric proteins with asymmetrical CH2-CH3 region mutations
|
|
KR102692379B1
(ko)
|
2017-06-05 |
2024-08-05 |
얀센 바이오테크 인코포레이티드 |
Pd-1과 특이적으로 결합하는 항체 및 사용 방법
|
|
US20190031774A1
(en)
|
2017-06-09 |
2019-01-31 |
Sanofi Biotechnology |
Methods for treating hyperlipidemia in diabetic patients by administering a pcsk9 inhibitor
|
|
US10806780B2
(en)
|
2017-06-28 |
2020-10-20 |
Regeneron Pharmaceuticals, Inc. |
Anti-human papillomavirus (HPV) antigen-binding proteins and methods of use thereof
|
|
AU2018304458B2
(en)
|
2017-07-21 |
2021-12-09 |
Foundation Medicine, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
CA3066793C
(en)
|
2017-07-21 |
2023-06-20 |
Werner Mueller |
Single chain vh and heavy chain antibodies
|
|
JP7304846B2
(ja)
|
2017-07-24 |
2023-07-07 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
抗cd8抗体およびその使用
|
|
EP3658581A1
(en)
|
2017-07-24 |
2020-06-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies and peptides to treat hcmv related diseases
|
|
TWI799432B
(zh)
|
2017-07-27 |
2023-04-21 |
美商再生元醫藥公司 |
抗ctla-4抗體及其用途
|
|
CA3057447A1
(en)
|
2017-08-03 |
2019-02-07 |
Alector Llc |
Anti-cd33 antibodies and methods of use thereof
|
|
KR20200045520A
(ko)
|
2017-09-07 |
2020-05-04 |
오거스타 유니버시티 리서치 인스티튜트, 인크. |
프로그래밍된 세포사 단백질 1에 대한 항체
|
|
IL273202B2
(en)
|
2017-09-11 |
2024-08-01 |
Univ Monash |
Binding proteins to the human thrombin receptor, par4
|
|
CN111148758B
(zh)
|
2017-09-29 |
2022-12-09 |
瑞泽恩制药公司 |
结合葡萄球菌属靶抗原和补体成分的双特异性抗原结合分子及其用途
|
|
EP3690050A4
(en)
|
2017-09-29 |
2021-06-16 |
Chugai Seiyaku Kabushiki Kaisha |
MULTISPECIFIC ANTIGENBINDING MOLECULE WITH BLOOD CLOG FACTOR VIII (FVIII) COFACTOR FUNCTION SUBSTITUATING ACTIVITY AND PHARMACEUTICAL FORMULATION WITH THIS MOLECULE AS THE ACTIVE SUBSTANCE
|
|
DK3476942T3
(da)
|
2017-10-27 |
2022-04-19 |
Trianni Inc |
Lange kimlinje-dh-gener og antistoffer med lang hcdr3
|
|
KR20250044796A
(ko)
|
2017-10-30 |
2025-04-01 |
사노피 바이오테크놀로지 |
Il-4r 길항제를 투여하여 천식을 치료 또는 예방하는 방법
|
|
ES2907054T3
(es)
|
2017-11-01 |
2022-04-21 |
Hoffmann La Roche |
TriFab-Contorsbody
|
|
WO2019086394A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
The compbody - a multivalent target binder
|
|
JP7544597B2
(ja)
|
2017-11-06 |
2024-09-03 |
ジェネンテック, インコーポレイテッド |
がんの診断及び療法
|
|
CN111601619A
(zh)
|
2017-11-07 |
2020-08-28 |
里珍纳龙药品有限公司 |
用于抗体药物偶联物的亲水性连接体
|
|
EP3710589A4
(en)
|
2017-11-14 |
2021-11-10 |
Chugai Seiyaku Kabushiki Kaisha |
ANTI-C1S ANTIBODIES AND METHOD OF USING
|
|
US11066474B2
(en)
|
2017-11-30 |
2021-07-20 |
Regeneron Pharmaceuticals, Inc. |
Anti-TrkB monoclonal antibodies and methods of use
|
|
SG11202003044SA
(en)
*
|
2017-12-05 |
2020-04-29 |
Regeneron Pharma |
Non-human animals having an engineered immunoglobulin lambda light chain and uses thereof
|
|
KR20200098528A
(ko)
|
2017-12-13 |
2020-08-20 |
리제너론 파아마슈티컬스, 인크. |
항-c5 항체 조합물 및 이의 용도
|
|
US11977081B2
(en)
|
2017-12-18 |
2024-05-07 |
Regeneron Pharmaceuticals, Inc. |
ANGPTL8 assay and uses thereof
|
|
MA51302A
(fr)
|
2017-12-21 |
2021-03-31 |
Hoffmann La Roche |
Anticorps se liant à hla-a2/wt1
|
|
US20190211098A1
(en)
|
2017-12-22 |
2019-07-11 |
Genentech, Inc. |
Use of pilra binding agents for treatment of a disease
|
|
CA3087166A1
(en)
|
2017-12-22 |
2019-06-27 |
Jounce Therapeutics, Inc. |
Antibodies to lilrb2
|
|
KR102845020B1
(ko)
|
2017-12-28 |
2025-08-12 |
난징 레전드 바이오테크 씨오., 엘티디. |
Pd-l1에 대한 항체 및 변이체
|
|
JP7369127B2
(ja)
|
2017-12-28 |
2023-10-25 |
ナンジン レジェンド バイオテック カンパニー,リミテッド |
Tigitに対する単一ドメイン抗体及びその変異体
|
|
US11440957B2
(en)
|
2017-12-29 |
2022-09-13 |
Alector Llc |
Anti-TMEM106B antibodies and methods of use thereof
|
|
US12070506B2
(en)
|
2018-01-08 |
2024-08-27 |
Regeneron Pharmaceuticals, Inc. |
Steroids and antibody-conjugates thereof
|
|
WO2019139987A1
(en)
|
2018-01-09 |
2019-07-18 |
Elstar Therapeutics, Inc. |
Calreticulin binding constructs and engineered t cells for the treatment of diseases
|
|
KR102839330B1
(ko)
|
2018-01-15 |
2025-07-30 |
난징 레전드 바이오테크 씨오., 엘티디. |
Pd-1에 대한 단일-도메인 항체 및 이의 변이체
|
|
US20200339686A1
(en)
|
2018-01-16 |
2020-10-29 |
Lakepharma, Inc. |
Bispecific antibody that binds cd3 and another target
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
KR20200115576A
(ko)
|
2018-01-26 |
2020-10-07 |
리제너론 파아마슈티컬스, 인크. |
항-tmprss2 항체 및 항원-결합 단편
|
|
CA3088194A1
(en)
|
2018-01-26 |
2019-08-01 |
Regeneron Pharmaceuticals, Inc. |
Human antibodies to influenza hemagglutinin
|
|
EP3746476A1
(en)
|
2018-01-31 |
2020-12-09 |
Alector LLC |
Anti-ms4a4a antibodies and methods of use thereof
|
|
WO2019152895A1
(en)
|
2018-02-01 |
2019-08-08 |
Memorial Sloan Kettering Cancer Center |
Antibodies to galectin-3 and methods of use thereof
|
|
CA3089287A1
(en)
|
2018-02-08 |
2019-08-15 |
Genentech, Inc. |
Bispecific antigen-binding molecules and methods of use
|
|
JP7418337B2
(ja)
|
2018-02-09 |
2024-01-19 |
ジェネンテック, インコーポレイテッド |
マスト細胞媒介性炎症性疾患の治療法及び診断法
|
|
CA3090538A1
(en)
|
2018-02-09 |
2019-08-15 |
Acceleron Pharma, Inc. |
Methods for treating heterotopic ossification
|
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
|
AU2019225249A1
(en)
|
2018-02-26 |
2020-09-17 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-PD-L1 antagonist antibodies
|
|
AU2019231703A1
(en)
|
2018-03-06 |
2020-10-22 |
Regeneron Pharmaceuticals, Inc. |
Use of PCSK9 inhibitor for reducing cardiovascular risk
|
|
WO2019178362A1
(en)
|
2018-03-14 |
2019-09-19 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
US20200040103A1
(en)
|
2018-03-14 |
2020-02-06 |
Genentech, Inc. |
Anti-klk5 antibodies and methods of use
|
|
IL277375B2
(en)
|
2018-03-15 |
2025-08-01 |
Chugai Pharmaceutical Co Ltd |
Anti-dengue virus antibodies having cross-reactivity to zika virus and methods of use
|
|
ES2987813T3
(es)
|
2018-03-24 |
2024-11-18 |
Regeneron Pharma |
Métodos para identificar péptidos tumorales asociados al HLA
|
|
US20210051929A1
(en)
|
2018-03-24 |
2021-02-25 |
Regeneron Pharmaceuticals, Inc. |
Genetically modified non-human animals for generating therapeutic antibodies against peptide-mhc complexes, methods of making and uses thereof
|
|
CA3093850A1
(en)
|
2018-03-26 |
2019-10-03 |
Regeneron Pharmaceuticals, Inc. |
Humanized rodents for testing therapeutic agents
|
|
CA3094981A1
(en)
|
2018-03-26 |
2019-10-03 |
Regeneron Pharmaceuticals, Inc. |
Anti-pfrh5 antibodies and antigen-binding fragments thereof
|
|
KR20200135510A
(ko)
|
2018-03-29 |
2020-12-02 |
제넨테크, 인크. |
포유류 세포들에서 젖분비자극 활성의 조절
|
|
US11958903B2
(en)
|
2018-03-30 |
2024-04-16 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies against LAG-3 and uses thereof
|
|
JP7104458B2
(ja)
|
2018-04-02 |
2022-07-21 |
上海博威生物医薬有限公司 |
リンパ球活性化遺伝子-3(lag-3)結合抗体およびその使用
|
|
TW202011029A
(zh)
|
2018-04-04 |
2020-03-16 |
美商建南德克公司 |
偵測及定量fgf21之方法
|
|
CA3094400A1
(en)
|
2018-04-06 |
2019-10-10 |
Regeneron Pharmaceuticals, Inc. |
A leptin receptor agonist antibody for use in treating a metabolic dysfunction or hypoleptinemia
|
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
|
AR114789A1
(es)
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
|
US11958895B2
(en)
|
2018-05-03 |
2024-04-16 |
University Of Rochester |
Anti-influenza neuraminidase monoclonal antibodies and uses thereof
|
|
AU2019265703A1
(en)
|
2018-05-09 |
2020-11-19 |
Regeneron Pharmaceuticals, Inc. |
Anti-MSR1 antibodies and methods of use thereof
|
|
MA52777A
(fr)
|
2018-05-24 |
2021-04-14 |
Janssen Biotech Inc |
Agents de liaison psma et utilisations correspondantes
|
|
SMT202500221T1
(it)
|
2018-05-24 |
2025-07-22 |
Janssen Biotech Inc |
Anticorpi anti-cd3 e usi di essi
|
|
JP2021524255A
(ja)
|
2018-05-24 |
2021-09-13 |
ヤンセン バイオテツク,インコーポレーテツド |
単一特異性及び二重特異性抗体抗−tmeff2抗体並びにそれらの使用
|
|
JP7337099B2
(ja)
|
2018-05-25 |
2023-09-01 |
アレクトル エルエルシー |
抗sirpa抗体およびその使用法
|
|
CN112533948B
(zh)
|
2018-05-31 |
2025-01-14 |
台湾醣联生技医药股份有限公司 |
与双触角Lewis B以及Lewis Y抗原结合的治疗性抗体
|
|
US11987629B2
(en)
|
2018-06-01 |
2024-05-21 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
Compositions and uses thereof for treating disease or condition
|
|
WO2019227490A1
(en)
|
2018-06-01 |
2019-12-05 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
Compositions and methods for imaging
|
|
EP3811364A1
(en)
|
2018-06-01 |
2021-04-28 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for sparse vector-based matrix transformations
|
|
IL318469A
(en)
|
2018-06-14 |
2025-03-01 |
Regeneron Pharma |
Non-human animals capable of reorganizing transgenic DH-DH, and their uses
|
|
MA52966A
(fr)
|
2018-06-19 |
2021-04-28 |
Regeneron Pharma |
Anticorps anti-facteur xii/xiia et leurs utilisations
|
|
SG11202012446UA
(en)
|
2018-06-23 |
2021-01-28 |
Genentech Inc |
Methods of treating lung cancer with a pd-1 axis binding antagonist, a platinum agent, and a topoisomerase ii inhibitor
|
|
EA202190138A1
(ru)
|
2018-06-29 |
2021-05-27 |
ЭЛЕКТОР ЭлЭлСи |
Анти-sirp-бета1 антитела и способы их использования
|
|
AU2019297451A1
(en)
|
2018-07-03 |
2021-01-28 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
|
AU2019302642B2
(en)
|
2018-07-10 |
2025-10-30 |
Regeneron Pharmaceuticals, Inc. |
Modifying binding molecules to minimize pre-existing interactions
|
|
US11396546B2
(en)
|
2018-07-13 |
2022-07-26 |
Alector Llc |
Anti-Sortilin antibodies and methods of use thereof
|
|
EP3823989A2
(en)
|
2018-07-16 |
2021-05-26 |
Regeneron Pharmaceuticals, Inc. |
Anti-il36r antibodies
|
|
KR20210041557A
(ko)
|
2018-07-17 |
2021-04-15 |
후맙스 바이오메드 에스에이 |
캄필로박터 종에 대한 항체
|
|
EP3823611A1
(en)
|
2018-07-18 |
2021-05-26 |
Genentech, Inc. |
Methods of treating lung cancer with a pd-1 axis binding antagonist, an antimetabolite, and a platinum agent
|
|
CA3107463A1
(en)
|
2018-07-24 |
2020-01-30 |
Medimmune, Llc |
Antibody directed against s. aureus clumping factor a (clfa)
|
|
SG10202106830VA
(en)
|
2018-08-10 |
2021-08-30 |
Chugai Pharmaceutical Co Ltd |
Anti-cd137 antigen-binding molecule and utilization thereof
|
|
JP7460598B2
(ja)
|
2018-08-10 |
2024-04-02 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
膝および/または股関節痛の安全で効果的な処置用の医薬組成物
|
|
TW202021618A
(zh)
|
2018-08-17 |
2020-06-16 |
美商23與我有限公司 |
抗il1rap抗體及其使用方法
|
|
TWI868074B
(zh)
|
2018-08-29 |
2025-01-01 |
美商再生元醫藥公司 |
用來治療患有類風濕性關節炎之個體的方法及組成物
|
|
BR112021003016A2
(pt)
|
2018-08-31 |
2021-05-18 |
Alector Llc |
anticorpos isolados, ácido nucleico isolado, vetor, célula hospedeira, métodos para produzir um anticorpo e para prevenir, reduzir o risco ou tratar uma doença e composição farmacêutica
|
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
|
CA3110750A1
(en)
|
2018-09-10 |
2020-03-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies against cd33 and constructs thereof
|
|
US20220053741A1
(en)
|
2018-09-13 |
2022-02-24 |
Regeneron Pharmaceuticals, Inc. |
Complement Factor H Gene Knockout Rat as a Model of C3 Glomerulopathy
|
|
KR20210063330A
(ko)
|
2018-09-19 |
2021-06-01 |
제넨테크, 인크. |
방광암에 대한 치료 및 진단 방법
|
|
AU2019342133B8
(en)
|
2018-09-21 |
2025-08-07 |
Genentech, Inc. |
Diagnostic methods for triple-negative breast cancer
|
|
CN113164602A
(zh)
|
2018-10-09 |
2021-07-23 |
免疫医疗有限责任公司 |
抗金黄色葡萄球菌抗体的组合
|
|
TW202028244A
(zh)
|
2018-10-09 |
2020-08-01 |
美商建南德克公司 |
用於確定突觸形成之方法及系統
|
|
KR20210079311A
(ko)
|
2018-10-18 |
2021-06-29 |
제넨테크, 인크. |
육종성 신장암에 대한 진단과 치료 방법
|
|
SG11202101037QA
(en)
|
2018-10-23 |
2021-02-25 |
Regeneron Pharma |
Anti-npr1 antibodies and uses thereof
|
|
EP3870235A1
(en)
|
2018-10-24 |
2021-09-01 |
F. Hoffmann-La Roche AG |
Conjugated chemical inducers of degradation and methods of use
|
|
JP7415939B2
(ja)
|
2018-10-31 |
2024-01-17 |
アステラス製薬株式会社 |
抗ヒトFn14抗体
|
|
EP3877413A1
(en)
|
2018-11-06 |
2021-09-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of acute myeloid leukemia by eradicating leukemic stem cells
|
|
CN112867732A
(zh)
|
2018-11-21 |
2021-05-28 |
瑞泽恩制药公司 |
抗葡萄球菌抗体和其用途
|
|
KR20210100668A
(ko)
|
2018-12-06 |
2021-08-17 |
제넨테크, 인크. |
항-CD79b 면역접합체, 알킬화제 및 항-CD20 항체를 포함하는 미만성 큰 B-세포 림프종의 조합 요법
|
|
EP3894427A1
(en)
|
2018-12-10 |
2021-10-20 |
Genentech, Inc. |
Photocrosslinking peptides for site specific conjugation to fc-containing proteins
|
|
US20220064260A1
(en)
|
2018-12-14 |
2022-03-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Isolated mhc-derived human peptides and uses thereof for stimulating and activating the suppressive function of cd8+cd45rclow tregs
|
|
GB201820554D0
(en)
|
2018-12-17 |
2019-01-30 |
Univ Oxford Innovation Ltd |
BTLA antibodies
|
|
GB201820547D0
(en)
|
2018-12-17 |
2019-01-30 |
Oxford Univ Innovation |
Modified antibodies
|
|
CN113423831B
(zh)
|
2018-12-20 |
2023-03-10 |
瑞泽恩制药公司 |
核酸酶介导的重复扩增
|
|
AR117327A1
(es)
|
2018-12-20 |
2021-07-28 |
23Andme Inc |
Anticuerpos anti-cd96 y métodos de uso de estos
|
|
TW202035442A
(zh)
|
2018-12-20 |
2020-10-01 |
美商建南德克公司 |
經修飾之抗體Fc及其使用方法
|
|
WO2020132214A2
(en)
|
2018-12-20 |
2020-06-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Ebola virus glycoprotein-specific monoclonal antibodies and uses thereof
|
|
AU2019405782A1
(en)
|
2018-12-21 |
2021-06-17 |
23Andme, Inc. |
Anti-IL-36 antibodies and methods of use thereof
|
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
|
JP2022518399A
(ja)
|
2019-01-14 |
2022-03-15 |
ジェネンテック, インコーポレイテッド |
Pd-1軸結合アンタゴニスト及びrnaワクチンを用いてがんを処置する方法
|
|
BR112021014276A2
(pt)
|
2019-01-22 |
2021-09-28 |
Genentech, Inc. |
Anticorpos iga isolados, moléculas de fusão igg-iga isoladas, ácido nucleico isolado, célula hospedeira, método para produzir um anticorpo, para tratar um indivíduo, para aumentar a expressão de dímeros, trímeros ou tetrâmeros, para aumentar a produção de polímeros, para aumentar a produção de dímeros, para aumentar a produção de um polímero, para diminuir a produção de polímeros, para aumentar a expressão transitória de um anticorpo, para expressar dímeros de moléculas de fusão, para expressar dímeros, trímeros ou tetrâmeros, para purificar um anticorpo, para purificar um estado oligomérico de um anticorpo, composição farmacêutica e uso do anticorpo
|
|
CN113795511B
(zh)
|
2019-01-23 |
2024-07-23 |
大有华夏生物医药集团有限公司 |
抗pd-l1双抗体及其用途
|
|
EP3915581A4
(en)
|
2019-01-24 |
2023-03-22 |
Chugai Seiyaku Kabushiki Kaisha |
NOVEL CANCER ANTIGENS AND ANTIBODIES OF THESE ANTIGENS
|
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
|
CN120157765A
(zh)
|
2019-02-01 |
2025-06-17 |
瑞泽恩制药公司 |
抗IL2受体γ抗原结合蛋白
|
|
EP3923978A1
(en)
|
2019-02-12 |
2021-12-22 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for using bispecific antibodies to bind complement and a target antigen
|
|
US12109273B2
(en)
|
2019-02-15 |
2024-10-08 |
Wuxi Xdc Singapore Private Limited |
Process for preparing antibody-drug conjugates with improved homogeneity
|
|
US11478553B2
(en)
|
2019-02-15 |
2022-10-25 |
Wuxi Biologies Ireland Limited |
Process for preparing antibody-drug conjugates with improved homogeneity
|
|
EP3927832A4
(en)
*
|
2019-02-18 |
2022-11-30 |
Biocytogen Pharmaceuticals (Beijing) Co., Ltd. |
GENETICALLY MODIFIED NON-HUMAN ANIMALS WITH HUMANIZED IMMUNOGLOBULIN LOCUS
|
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
|
GB2599228B
(en)
|
2019-02-21 |
2024-02-07 |
Marengo Therapeutics Inc |
Multifunctional molecules that bind to T cell related cancer cells and uses thereof
|
|
AU2020224681A1
(en)
|
2019-02-21 |
2021-09-16 |
Marengo Therapeutics, Inc. |
Antibody molecules that bind to NKp30 and uses thereof
|
|
US11464217B2
(en)
|
2019-02-22 |
2022-10-11 |
Regeneron Pharmaceuticals, Inc. |
Rodents having genetically modified sodium channels and methods of use thereof
|
|
CN113710706A
(zh)
|
2019-02-27 |
2021-11-26 |
豪夫迈·罗氏有限公司 |
用于抗tigit抗体和抗cd20抗体或抗cd38抗体治疗的给药
|
|
BR112021016984A2
(pt)
|
2019-03-01 |
2021-11-30 |
Allogene Therapeutics Inc |
Receptores de antígeno quimérico direcionados a dll3 e agentes de ligação
|
|
MX2021010565A
(es)
|
2019-03-08 |
2021-10-13 |
Genentech Inc |
Metodos para detectar y cuantificar proteinas asociadas a la membrana en vesiculas extracelulares.
|
|
IL286917B
(en)
|
2019-04-04 |
2022-09-01 |
Regeneron Pharma |
Methods for scarless introduction of targeted modifications into targeting vectors
|
|
CN117178959A
(zh)
|
2019-04-04 |
2023-12-08 |
瑞泽恩制药公司 |
包括人源化凝血因子12基因座的非人动物
|
|
MX2021012335A
(es)
|
2019-04-10 |
2021-11-12 |
Regeneron Pharma |
Anticuerpos humanos que se unen a ret y metodos de uso de los mismos.
|
|
KR20210153092A
(ko)
|
2019-04-15 |
2021-12-16 |
퀴셀 세라퓨틱스 엘엘씨 |
암 치료에 사용하기 위한, 마스킹된 유형 i 인터페론(ifna 및 ifnb) 및 종양 항원에 대한 항체를 포함하는 융합 단백질 조성물
|
|
TW202043291A
(zh)
|
2019-04-19 |
2020-12-01 |
美商建南德克公司 |
抗mertk抗體及使用方法
|
|
AR118720A1
(es)
|
2019-04-19 |
2021-10-27 |
Janssen Biotech Inc |
Métodos para tratar el cáncer de próstata con un anticuerpo anti-psma / cd3
|
|
AU2020261411B2
(en)
|
2019-04-26 |
2025-10-02 |
Allogene Therapeutics, Inc. |
Methods of manufacturing allogeneic car T cells
|
|
EP3962515A1
(en)
|
2019-05-01 |
2022-03-09 |
Sanofi Biotechnology |
Methods for treating or preventing asthma by administering an il-33 antagonist
|
|
US12269872B2
(en)
|
2019-05-03 |
2025-04-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to Plasmodium falciparum circumsporozoite protein and their use
|
|
WO2020226986A2
(en)
|
2019-05-03 |
2020-11-12 |
Genentech, Inc. |
Methods of treating cancer with an anti-pd-l1 antibody
|
|
EP3968993A1
(en)
|
2019-05-14 |
2022-03-23 |
F. Hoffmann-La Roche AG |
Methods of using anti-cd79b immunoconjugates to treat follicular lymphoma
|
|
US20230085439A1
(en)
|
2019-05-21 |
2023-03-16 |
University Of Georgia Research Foundation, Inc. |
Antibodies that bind human metapneumovirus fusion protein and their use
|
|
AU2020286382A1
(en)
|
2019-06-04 |
2021-11-04 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals comprising a humanized TTR locus with a beta-slip mutation and methods of use
|
|
SG11202111258TA
(en)
|
2019-06-05 |
2021-11-29 |
Regeneron Pharma |
Non-human animals having a limited lambda light chain repertoire expressed from the kappa locus and uses thereof
|
|
MX2021015122A
(es)
|
2019-06-07 |
2022-04-06 |
Regeneron Pharma |
Animales no humanos que comprenden un locus de albumina humanizado.
|
|
WO2020252066A1
(en)
|
2019-06-11 |
2020-12-17 |
Alector Llc |
Anti-sortilin antibodies for use in therapy
|
|
AU2020292283A1
(en)
|
2019-06-11 |
2021-12-23 |
Regeneron Pharmaceuticals, Inc. |
Anti-PcrV antibodies that bind PcrV, compositions comprising anti-PcrV antibodies, and methods of use thereof
|
|
WO2020251924A1
(en)
|
2019-06-12 |
2020-12-17 |
Regeneron Pharmaceuticals, Inc. |
Human antibodies to bone morphogenetic protein 6
|
|
CN118453851A
(zh)
|
2019-06-21 |
2024-08-09 |
瑞泽恩制药公司 |
结合muc16和cd3的双特异性抗原结合分子与4-1bb共刺激组合的用途
|
|
CN114025802B
(zh)
|
2019-06-21 |
2024-04-23 |
瑞泽恩制药公司 |
结合psma和cd3的双特异性抗原结合分子与4-1bb共刺激组合的用途
|
|
JP2022540395A
(ja)
|
2019-06-29 |
2022-09-15 |
ハンジョウ ディーエーシー バイオテック シーオー.,エルティディ. |
細胞結合性分子-チューブリシン誘導体共役体及びその調製方法
|
|
EP3993623B1
(en)
|
2019-07-01 |
2025-02-19 |
Trianni, Inc. |
Transgenic rodents and methods of use thereof
|
|
CN114502725B
(zh)
|
2019-07-01 |
2025-09-12 |
特里安尼公司 |
转基因哺乳动物及使用方法
|
|
WO2021001289A1
(en)
|
2019-07-02 |
2021-01-07 |
F. Hoffmann-La Roche Ag |
Immunoconjugates comprising a mutant interleukin-2 and an anti-cd8 antibody
|
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
|
JP7592064B2
(ja)
|
2019-07-16 |
2024-11-29 |
サノフィ・バイオテクノロジー |
Il-4rアンタゴニストを投与することにより喘息を治療するまたは予防するための方法
|
|
CA3147735A1
(en)
|
2019-07-26 |
2021-02-04 |
Janssen Biotech, Inc. |
Proteins comprising kallikrein related peptidase 2 antigen binding domains and their uses
|
|
CN114174338A
(zh)
|
2019-07-31 |
2022-03-11 |
豪夫迈·罗氏有限公司 |
与gprc5d结合的抗体
|
|
BR112022001460A2
(pt)
|
2019-07-31 |
2022-03-22 |
Hoffmann La Roche |
Moléculas de ligação ao antígeno biespecíficas, um ou mais polinucleotídeos isolados, célula hospedeira, método para produzir uma molécula de ligação ao antígeno biespecífica e para tratar uma doença em um indivíduo, composição farmacêutica, uso da molécula de ligação ao antígeno biespecífica e invenção
|
|
EP4003519A2
(en)
|
2019-07-31 |
2022-06-01 |
Alector LLC |
Anti-ms4a4a antibodies and methods of use thereof
|
|
AU2020326713A1
(en)
|
2019-08-05 |
2022-02-17 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating atopic dermatitis by administering an il-4r antagonist
|
|
US11504426B2
(en)
|
2019-08-05 |
2022-11-22 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R antagonist
|
|
AU2020328507A1
(en)
|
2019-08-12 |
2022-03-17 |
Purinomia Biotech, Inc. |
Methods and compositions for promoting and potentiating T-cell mediated immune responses through ADCC targeting of CD39 expressing cells
|
|
CA3148121A1
(en)
|
2019-08-15 |
2021-02-18 |
Janssen Biotech, Inc. |
Materials and methods for improved single chain variable fragments
|
|
DK3785536T4
(da)
|
2019-08-28 |
2025-10-27 |
Trianni Inc |
Adam6-knockin-mus
|
|
KR20220062304A
(ko)
|
2019-09-12 |
2022-05-16 |
제넨테크, 인크. |
루푸스 신장염을 치료하는 조성물과 방법
|
|
AR119997A1
(es)
|
2019-09-18 |
2022-01-26 |
Genentech Inc |
Anticuerpos anti-klk7, anticuerpos anti-klk5, anticuerpos multiespecíficos anti-klk5 / klk7 y métodos de uso
|
|
CA3147179A1
(en)
|
2019-09-20 |
2021-03-25 |
Joseph Haw-Ling Lin |
Dosing for anti-tryptase antibodies
|
|
MX2022003610A
(es)
|
2019-09-27 |
2022-04-20 |
Genentech Inc |
Administracion de dosis para tratamiento con anticuerpos antagonistas anti-tigit y anti-pd-l1.
|
|
WO2021058763A1
(en)
|
2019-09-27 |
2021-04-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-müllerian inhibiting substance antibodies and uses thereof
|
|
EP4034160A1
(en)
|
2019-09-27 |
2022-08-03 |
Janssen Biotech, Inc. |
Anti-ceacam antibodies and uses thereof
|
|
WO2021057978A1
(zh)
|
2019-09-27 |
2021-04-01 |
南京金斯瑞生物科技有限公司 |
抗vhh域抗体及其用途
|
|
WO2021058729A1
(en)
|
2019-09-27 |
2021-04-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-müllerian inhibiting substance type i receptor antibodies and uses thereof
|
|
CA3154710A1
(en)
|
2019-10-04 |
2021-04-08 |
TAE Life Sciences |
Antibody compositions comprising fc mutations and site-specific conjugation properties
|
|
CR20220166A
(es)
|
2019-10-18 |
2022-06-15 |
Genentech Inc |
Métodos para usar inmunoconjugados anti-cd79b para tratar linfoma difuso de linfocitos b grandes
|
|
CN114761428A
(zh)
|
2019-10-28 |
2022-07-15 |
瑞泽恩制药公司 |
抗血凝素抗体及其使用方法
|
|
KR20220092580A
(ko)
|
2019-11-06 |
2022-07-01 |
제넨테크, 인크. |
혈액암의 치료를 위한 진단과 치료 방법
|
|
TWI895295B
(zh)
|
2019-11-12 |
2025-09-01 |
美商方得生醫療公司 |
偵測編碼新生抗原之融合基因之方法
|
|
BR112022008172A2
(pt)
|
2019-11-15 |
2022-07-12 |
Hoffmann La Roche |
Composição aquosa estável, método para obter uma composição e forma de dosagem farmacêutica
|
|
PH12022551208A1
(en)
|
2019-11-18 |
2023-04-24 |
Janssen Biotech Inc |
Vaccines based on mutant calr and jak2 and their uses
|
|
EP4061944A1
(en)
|
2019-11-22 |
2022-09-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Inhibitors of adrenomedullin for the treatment of acute myeloid leukemia by eradicating leukemic stem cells
|
|
WO2021108363A1
(en)
|
2019-11-25 |
2021-06-03 |
Regeneron Pharmaceuticals, Inc. |
Crispr/cas-mediated upregulation of humanized ttr allele
|
|
WO2021108448A1
(en)
|
2019-11-25 |
2021-06-03 |
Mabloc, Llc |
Anti-yellow fever virus antibodies, and methods of their generation and use
|
|
CN114901678A
(zh)
|
2019-12-02 |
2022-08-12 |
瑞泽恩制药公司 |
肽-mhc ii蛋白构建体及其用途
|
|
MX2022006812A
(es)
|
2019-12-06 |
2022-08-25 |
Sanofi Biotechnology |
Metodos para tratar epoc mediante la administracion de un antagonista de il-33.
|
|
BR112022011098A2
(pt)
|
2019-12-09 |
2022-09-20 |
Sanofi Biotechnology |
Métodos para tratamento de distúrbios relacionados a il-4/il-13 digitalmente identificados
|
|
EP3992974A1
(en)
|
2020-11-02 |
2022-05-04 |
Sanofi Biotechnology |
Methods for treating digitally-identified il-4/il-13 related disorders
|
|
EP4072672A1
(en)
|
2019-12-10 |
2022-10-19 |
Regeneron Pharmaceuticals, Inc. |
Use of a pcsk9 inhibitor to treat homozygous familial hypercholesterolemia
|
|
CN115151307A
(zh)
|
2019-12-13 |
2022-10-04 |
艾莱克特有限责任公司 |
抗mertk抗体和其使用方法
|
|
AR120741A1
(es)
|
2019-12-13 |
2022-03-16 |
Genentech Inc |
Anticuerpos anti-ly6g6d y métodos de uso
|
|
EP4076666A1
(en)
|
2019-12-18 |
2022-10-26 |
F. Hoffmann-La Roche AG |
Antibodies binding to hla-a2/mage-a4
|
|
AU2020404453B2
(en)
|
2019-12-20 |
2022-12-08 |
Hudson Institute of Medical Research |
CXCL10 binding proteins and uses thereof
|
|
EP4081544A1
(en)
|
2019-12-23 |
2022-11-02 |
Sanofi Biotechnology |
Methods for treating or preventing allergic asthma by administering an il-33 antagonist and/or an il-4r antagonist
|
|
UA128549C2
(uk)
|
2019-12-27 |
2024-08-07 |
Чугаі Сейяку Кабусікі Кайся |
Антитіло до ctla-4 та його застосування
|
|
JP2023509708A
(ja)
|
2020-01-03 |
2023-03-09 |
マレンゴ・セラピューティクス,インコーポレーテッド |
抗tcr抗体分子およびその使用
|
|
IL294319A
(en)
|
2020-01-08 |
2022-08-01 |
Regeneron Pharma |
Using amino acids to improve signals in mass spectrometry tests
|
|
CN110818795B
(zh)
|
2020-01-10 |
2020-04-24 |
上海复宏汉霖生物技术股份有限公司 |
抗tigit抗体和使用方法
|
|
CN115348874A
(zh)
|
2020-01-24 |
2022-11-15 |
里珍纳龙药品有限公司 |
蛋白质-抗病毒化合物偶联物
|
|
IL294861A
(en)
|
2020-01-27 |
2022-09-01 |
Regeneron Pharma |
Tandem mass tag multiplexed quantitation of post-translational modifications of proteins
|
|
WO2022050954A1
(en)
|
2020-09-04 |
2022-03-10 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
WO2021154791A1
(en)
|
2020-01-28 |
2021-08-05 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals comprising a humanized pnpla3 locus and methods of use
|
|
EP4097464A1
(en)
|
2020-01-30 |
2022-12-07 |
Regeneron Pharmaceuticals, Inc. |
Platform for native liquid chromatography-mass spectrometry
|
|
AU2021212211A1
(en)
|
2020-01-31 |
2022-08-18 |
Regeneron Pharmaceuticals, Inc. |
High confidence compound identification by liquid chromatography-mass spectrometry
|
|
WO2021155149A1
(en)
|
2020-01-31 |
2021-08-05 |
Genentech, Inc. |
Methods of inducing neoepitope-specific t cells with a pd-1 axis binding antagonist and an rna vaccine
|
|
WO2021158521A1
(en)
|
2020-02-03 |
2021-08-12 |
Vir Biotechnology, Inc. |
Antibodies against sars-cov-2 and methods of using the same
|
|
CA3108168A1
(en)
|
2020-02-05 |
2021-08-05 |
Yue Zhang |
Conjugates of cell-binding molecules with cytotoxic agents
|
|
EP4099821A1
(en)
|
2020-02-07 |
2022-12-14 |
Regeneron Pharmaceuticals, Inc. |
<smallcaps/>? ? ?klkb1? ? ? ? ?non-human animals comprising a humanizedlocus and methods of use
|
|
WO2021160155A1
(zh)
|
2020-02-10 |
2021-08-19 |
上海诗健生物科技有限公司 |
密蛋白18.2的抗体及其用途
|
|
JP7772702B2
(ja)
|
2020-02-10 |
2025-11-18 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
抗tmprss2抗体および抗原結合断片
|
|
KR20220139357A
(ko)
|
2020-02-10 |
2022-10-14 |
상하이 에스쿠겐 바이오테크놀로지 컴퍼니 리미티드 |
Cldn18.2 항체 및 그의 사용
|
|
AU2021218675A1
(en)
|
2020-02-11 |
2022-08-18 |
Regeneron Pharmaceuticals, Inc. |
Anti-ACVR1 antibodies and uses thereof
|
|
IL295515A
(en)
|
2020-02-12 |
2022-10-01 |
Janssen Pharmaceutica Nv |
Fgfr tyrosine kinase inhibitors and anti-pd1 agents for the treatment of urothelial carcinoma
|
|
TWI895351B
(zh)
|
2020-02-12 |
2025-09-01 |
日商中外製藥股份有限公司 |
用於癌症之治療的抗cd137抗原結合分子
|
|
TW202144388A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在卵巢癌中表現之新抗原及其用途
|
|
TWI832035B
(zh)
|
2020-02-14 |
2024-02-11 |
美商基利科學股份有限公司 |
結合ccr8之抗體及融合蛋白及其用途
|
|
TW202144389A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在多發性骨髓瘤中表現之新抗原及其用途
|
|
HRP20231031T1
(hr)
|
2020-02-26 |
2023-12-22 |
Vir Biotechnology, Inc. |
Protutijela protiv sars-cov-2
|
|
KR20220145859A
(ko)
|
2020-02-28 |
2022-10-31 |
상하이 헨리우스 바이오테크, 인크. |
항cd137 작제물, 다중 특이적 항체 및 그 용도
|
|
JP7715722B2
(ja)
|
2020-02-28 |
2025-07-30 |
上海復宏漢霖生物技術股▲フン▼有限公司 |
抗cd137コンストラクト及びその使用
|
|
PH12022552371A1
(en)
|
2020-03-13 |
2023-12-18 |
Genentech Inc |
Anti-interleukin-33 antibodies and uses thereof
|
|
PE20240020A1
(es)
|
2020-03-13 |
2024-01-04 |
Janssen Biotech Inc |
Materiales y metodos para la union de siglec-3/cd33
|
|
WO2021188749A1
(en)
|
2020-03-19 |
2021-09-23 |
Genentech, Inc. |
Isoform-selective anti-tgf-beta antibodies and methods of use
|
|
EP4125348A1
(en)
|
2020-03-23 |
2023-02-08 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals comprising a humanized ttr locus comprising a v30m mutation and methods of use
|
|
KR20220157445A
(ko)
|
2020-03-24 |
2022-11-29 |
제넨테크, 인크. |
Tie2-결합제 및 사용방법
|
|
CA3169908A1
(en)
|
2020-03-26 |
2021-09-30 |
Genentech, Inc. |
Modified mammalian cells having reduced host cell proteins
|
|
AU2021244266A1
(en)
|
2020-03-27 |
2022-12-01 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating atopic dermatitis by administering an IL-4R antagonist
|
|
JP2023519962A
(ja)
|
2020-03-31 |
2023-05-15 |
アレクトル エルエルシー |
抗mertk抗体及びその使用方法
|
|
EP4126934A1
(en)
|
2020-04-01 |
2023-02-08 |
University of Rochester |
Monoclonal antibodies against the hemagglutinin (ha) and neuraminidase (na) of influenza h3n2 viruses
|
|
WO2021045836A1
(en)
|
2020-04-02 |
2021-03-11 |
Regeneron Pharmaceuticals, Inc. |
Anti-sars-cov-2-spike glycoprotein antibodies and antigen-binding fragments
|
|
EP4127724A1
(en)
|
2020-04-03 |
2023-02-08 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
WO2021203053A1
(en)
|
2020-04-03 |
2021-10-07 |
Vir Biotechnology, Inc. |
Immunotherapy targeting a conserved region in sars coronaviruses
|
|
IL297024A
(en)
|
2020-04-14 |
2022-12-01 |
Regeneron Pharma |
Ultraviolet monitoring of chromatography performance using orthogonal partial least squares
|
|
US20240059757A1
(en)
|
2020-04-14 |
2024-02-22 |
Vir Biotechnology, Inc. |
Antibodies against sars-cov-2 and methods of using the same
|
|
BR112022020629A2
(pt)
|
2020-04-15 |
2022-11-29 |
Hoffmann La Roche |
Polipeptídeo de interleucina-7 (il-7) mutante, imunoconjugado, um ou mais polinucleotídeos isolados, célula hospedeira, métodos para produzir um polipeptídeo il-7 mutante ou um imunoconjugado, para tratar uma doença e para estimular o sistema imunológico, polipeptídeo il-7 mutante, composição farmacêutica, uso do polipeptídeo il-7 mutante e invenção
|
|
KR20230004651A
(ko)
|
2020-04-16 |
2023-01-06 |
리제너론 파마슈티칼스 인코포레이티드 |
딜스-알더 접합 방법
|
|
US20230265204A1
(en)
|
2020-04-24 |
2023-08-24 |
Hoffmann-La Roche Inc. |
Enzyme and pathway modulation with sulfhydryl compounds and their derivatives
|
|
BR112022021441A2
(pt)
|
2020-04-24 |
2022-12-13 |
Genentech Inc |
Métodos para tratar linfoma folicular e linfoma difuso de grandes células b e kits
|
|
EP4143345A1
(en)
|
2020-04-28 |
2023-03-08 |
Genentech, Inc. |
Methods and compositions for non-small cell lung cancer immunotherapy
|
|
JP2023523480A
(ja)
|
2020-04-28 |
2023-06-06 |
ザ ロックフェラー ユニバーシティー |
中和抗sars-cov-2抗体およびその使用方法
|
|
EP4146283A1
(en)
|
2020-05-03 |
2023-03-15 |
Levena (Suzhou) Biopharma Co., Ltd. |
Antibody-drug conjugates (adcs) comprising an anti-trop-2 antibody, compositions comprising such adcs, as well as methods of making and using the same
|
|
BR112022022523A2
(pt)
|
2020-05-08 |
2023-01-10 |
Vir Biotechnology Inc |
Anticorpos contra sars-cov-2
|
|
BR112022022941A2
(pt)
|
2020-05-12 |
2023-01-10 |
Regeneron Pharma |
Anticorpos antagonistas anti-glp1r e métodos de uso dos mesmos
|
|
JP2023525053A
(ja)
|
2020-05-12 |
2023-06-14 |
インサーム(インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル) |
皮膚t細胞リンパ腫及びtfh由来リンパ腫を処置する新しい方法
|
|
EP4149421A1
(en)
|
2020-05-15 |
2023-03-22 |
F. Hoffmann-La Roche AG |
Prevention of visible particle formation in parenteral protein solutions
|
|
EP4153130A1
(en)
|
2020-05-19 |
2023-03-29 |
F. Hoffmann-La Roche AG |
The use of chelators for the prevention of visible particle formation in parenteral protein solutions
|
|
IL298257A
(en)
|
2020-05-22 |
2023-01-01 |
Regeneron Pharma |
Methods for treating eosinophilic esophagitis by administering an il-4r inhibitor
|
|
CN116096745A
(zh)
|
2020-05-26 |
2023-05-09 |
瑞泽恩制药公司 |
抗sars-cov-2纤突糖蛋白抗体和抗原结合片段
|
|
JP2023528350A
(ja)
|
2020-05-27 |
2023-07-04 |
ヤンセン バイオテツク,インコーポレーテツド |
Cd3抗原結合ドメインを含むタンパク質及びその使用
|
|
CN116323665A
(zh)
|
2020-05-29 |
2023-06-23 |
23和我公司 |
抗cd200r1抗体及其使用方法
|
|
CN116529260A
(zh)
|
2020-06-02 |
2023-08-01 |
当康生物技术有限责任公司 |
抗cd93构建体及其用途
|
|
WO2021247769A1
(en)
|
2020-06-02 |
2021-12-09 |
Dynamicure Biotechnology Llc |
Anti-cd93 constructs and uses thereof
|
|
IL298632A
(en)
|
2020-06-02 |
2023-01-01 |
Biocytogen Pharmaceuticals Beijing Co Ltd |
Non-human animals genetically modified with a common light chain immunoglobulin locus
|
|
WO2021247925A1
(en)
|
2020-06-03 |
2021-12-09 |
Vir Biotechnology, Inc. |
Structure-guided immunotherapy against sars-cov-2
|
|
IL298302A
(en)
|
2020-06-08 |
2023-01-01 |
Hoffmann La Roche |
Anti-hbv antibodies and methods of use
|
|
RU2751237C1
(ru)
*
|
2020-06-10 |
2021-07-12 |
Регенерон Фармасьютикалс, Инк. |
Способы и композиции для направленной модификации генома
|
|
GB202008860D0
(en)
|
2020-06-11 |
2020-07-29 |
Univ Oxford Innovation Ltd |
BTLA antibodies
|
|
BR112022025229A2
(pt)
|
2020-06-12 |
2023-03-07 |
Vir Biotechnology Inc |
Terapias de anticorpos para infecção por sars-cov-2
|
|
EP4165415A1
(en)
|
2020-06-12 |
2023-04-19 |
Genentech, Inc. |
Methods and compositions for cancer immunotherapy
|
|
WO2021257503A1
(en)
|
2020-06-16 |
2021-12-23 |
Genentech, Inc. |
Methods and compositions for treating triple-negative breast cancer
|
|
KR20230026407A
(ko)
|
2020-06-18 |
2023-02-24 |
리제너론 파아마슈티컬스, 인크. |
액티빈 a 항체 제형 및 이의 사용 방법
|
|
BR112022025801A2
(pt)
|
2020-06-18 |
2023-10-03 |
Hoffmann La Roche |
Métodos para tratar um paciente e para tratar um paciente com escc avançado, kit, anticorpo, uso de um anticorpo e uso de um antagonista de ligação
|
|
US20230235040A1
(en)
|
2020-06-22 |
2023-07-27 |
Almirall, S.A. |
Anti-il-36 antibodies and methods of use thereof
|
|
IL299161A
(en)
|
2020-06-24 |
2023-02-01 |
Genentech Inc |
Cell lines resistant to apoptosis
|
|
KR20230024822A
(ko)
|
2020-06-25 |
2023-02-21 |
주식회사 휴맵 |
이형접합성 형질전환 동물
|
|
US11897945B2
(en)
|
2020-07-01 |
2024-02-13 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating allergy using anti-Bet v 1 antibodies
|
|
WO2022009052A2
(en)
|
2020-07-06 |
2022-01-13 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
|
EP4178529A1
(en)
|
2020-07-07 |
2023-05-17 |
F. Hoffmann-La Roche AG |
Alternative surfactants as stabilizers for therapeutic protein formulations
|
|
BR112023000489A2
(pt)
|
2020-07-13 |
2023-03-28 |
Regeneron Pharma |
Análogos de camptotecina conjugados a um resíduo de glutamina em uma proteína, e seu uso
|
|
MX2023000617A
(es)
|
2020-07-17 |
2023-02-13 |
Genentech Inc |
Anticuerpos anti-notch2 y metodos de uso.
|
|
PE20231104A1
(es)
|
2020-07-21 |
2023-07-19 |
Genentech Inc |
Inductores quimicos de degradacion conjugados con anticuerpo de brm y metodos de estos
|
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
|
AU2021315665A1
(en)
|
2020-07-29 |
2023-03-16 |
Dynamicure Biotechnology Llc |
Anti-CD93 constructs and uses thereof
|
|
AU2021317111A1
(en)
|
2020-07-29 |
2023-03-30 |
Janssen Biotech, Inc. |
Proteins comprising HLA-G antigen binding domains and their uses
|
|
CA3188213A1
(en)
|
2020-08-07 |
2022-02-10 |
Robert C. Pordy |
Methods for treating refractory hypercholesterolemia involving an angptl3 inhibitor
|
|
EP3954393A1
(en)
|
2020-08-13 |
2022-02-16 |
Bioasis Technologies Inc. |
Combination therapies for delivery across the blood brain barrier
|
|
EP4204449A1
(en)
|
2020-08-26 |
2023-07-05 |
Regeneron Pharmaceuticals, Inc. |
Method of treating an allergy with allergen-specific monoclonal antibodies
|
|
TW202227625A
(zh)
|
2020-08-28 |
2022-07-16 |
美商建南德克公司 |
宿主細胞蛋白質之CRISPR/Cas9多重剔除
|
|
TW202229328A
(zh)
|
2020-09-11 |
2022-08-01 |
美商再生元醫藥公司 |
抗原特異性抗體之鑑定及產生
|
|
IL301269A
(en)
|
2020-09-14 |
2023-05-01 |
Ichnos Sciences S A |
Antibodies that bind to IL1RAP and their uses
|
|
US12280124B2
(en)
|
2020-09-14 |
2025-04-22 |
Regeneron Pharmaceuticals, Inc. |
Antibody-drug conjugates comprising GLP1 peptidomimetics and uses thereof
|
|
JP7641667B2
(ja)
|
2020-09-28 |
2025-03-07 |
アンジティア バイオメディスンズ リミテッド |
抗スクレロスチン構築体及びその使用
|
|
WO2022067269A2
(en)
|
2020-09-28 |
2022-03-31 |
Humabs Biomed Sa |
Antibodies against sars-cov-2
|
|
WO2022076462A1
(en)
|
2020-10-05 |
2022-04-14 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
AU2021357078A1
(en)
|
2020-10-05 |
2023-06-15 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating asthma in pediatric subjects by administering an il-4r antagonist
|
|
EP4248743A1
(en)
|
2020-10-08 |
2023-09-27 |
Humab Co. Ltd. |
Method for preparing transgenic non-human animal having genome including humanized immunoglobulin gene locus
|
|
CA3198590A1
(en)
|
2020-10-13 |
2022-04-21 |
Rajkumar Ganesan |
Bioengineered t cell mediated immunity, materials and other methods for modulating cluster of differentiation iv &/or viii
|
|
CA3198456A1
(en)
|
2020-10-14 |
2022-04-21 |
Five Prime Therapeutics, Inc. |
Anti-c-c chemokine receptor 8 (ccr8) antibodies and methods of use thereof
|
|
IL300024A
(en)
|
2020-10-20 |
2023-03-01 |
Hoffmann La Roche |
Combination therapy of PD-1 axis binding antagonists and LRRK2 inhibitors
|
|
IL301702A
(en)
|
2020-10-22 |
2023-05-01 |
Regeneron Pharma |
Anti-FGFR2 antibodies and methods of using them
|
|
TW202233672A
(zh)
|
2020-10-22 |
2022-09-01 |
美商健生生物科技公司 |
包括類δ配體3(DLL3)抗原結合區之蛋白質及其用途
|
|
WO2022093981A1
(en)
|
2020-10-28 |
2022-05-05 |
Genentech, Inc. |
Combination therapy comprising ptpn22 inhibitors and pd-l1 binding antagonists
|
|
IL302396A
(en)
|
2020-11-04 |
2023-06-01 |
Genentech Inc |
Dosage for treatment with bispecific anti-CD20/anti-CD3 antibodies
|
|
JP7716473B2
(ja)
|
2020-11-04 |
2025-07-31 |
ジェネンテック, インコーポレイテッド |
抗cd20/抗cd3二重特異性抗体の皮下投薬
|
|
EP4240758A1
(en)
|
2020-11-04 |
2023-09-13 |
The Rockefeller University |
Neutralizing anti-sars-cov-2 antibodies
|
|
IL302217A
(en)
|
2020-11-04 |
2023-06-01 |
Genentech Inc |
Dosage for treatment with bispecific anti-CD20/anti-CD3 antibodies and anti-CD79B drug antibody conjugates
|
|
CR20230244A
(es)
|
2020-11-16 |
2023-07-12 |
Astellas Pharma Inc |
Anticuerpo biespecífico anti-tspan8/anti-cd3 y anticuerpo anti-tspan8
|
|
EP4244248A1
(en)
|
2020-11-16 |
2023-09-20 |
F. Hoffmann-La Roche AG |
Fab high mannose glycoforms
|
|
MX2023005653A
(es)
|
2020-11-23 |
2023-07-31 |
Vir Biotechnology Inc |
Anticuerpos contra los virus de la influenza a.
|
|
JP2023551668A
(ja)
|
2020-11-23 |
2023-12-12 |
ヴィア・バイオテクノロジー・インコーポレイテッド |
インフルエンザのノイラミニダーゼに対する広域中和抗体
|
|
TW202235105A
(zh)
|
2020-11-23 |
2022-09-16 |
美商維爾生物科技股份有限公司 |
抗流感抗體及其組合
|
|
JP2023550785A
(ja)
|
2020-11-25 |
2023-12-05 |
ヴィア・バイオテクノロジー・インコーポレイテッド |
複数のベータコロナウイルスに結合する抗体
|
|
JP2023553399A
(ja)
|
2020-12-02 |
2023-12-21 |
アレクトル エルエルシー |
抗ソルチリン抗体の使用法
|
|
KR20230150779A
(ko)
|
2020-12-09 |
2023-10-31 |
트리아니, 인코포레이티드 |
중쇄-단독 항체
|
|
JP2024500399A
(ja)
|
2020-12-16 |
2024-01-09 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
ヒト化Fcアルファ受容体を発現するマウス
|
|
WO2022132904A1
(en)
|
2020-12-17 |
2022-06-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies targeting sars-cov-2
|
|
IL303656A
(en)
|
2020-12-17 |
2023-08-01 |
Hoffmann La Roche |
Anti-hla-g antibodies and use thereof
|
|
CA3202629A1
(en)
|
2020-12-18 |
2022-06-23 |
Regeneron Pharmaceuticals, Inc. |
Immunoglobulin proteins that bind to npr1 agonists
|
|
KR20230123498A
(ko)
|
2020-12-20 |
2023-08-23 |
리제너론 파아마슈티컬스, 인크. |
생체분자에서 스크램블된 디설파이드의 식별 방법
|
|
CA3197426A1
(en)
|
2020-12-23 |
2022-06-30 |
Regeneron Pharmaceuticals, Inc. |
Methods for obtaining antibodies that bind transmembrane proteins and cells that produce the same
|
|
IL303868A
(en)
|
2020-12-23 |
2023-08-01 |
Regeneron Pharma |
Nucleic acids encoding anchor-modified antibodies and uses thereof
|
|
US20220220211A1
(en)
|
2021-01-08 |
2022-07-14 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating peanut allergy and enhancing peanut allergen-specific immunotherapy by administering an il-4r antagonist
|
|
WO2022148853A1
(en)
|
2021-01-11 |
2022-07-14 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
|
EP4279594A4
(en)
|
2021-01-13 |
2024-11-27 |
Astellas Pharma Inc. |
BINDING OF MULTISPECIFIC ANTIBODIES TO ACTRIIA, ACTRIIB AND FN14
|
|
EP4277926A1
(en)
|
2021-01-15 |
2023-11-22 |
The Rockefeller University |
Neutralizing anti-sars-cov-2 antibodies
|
|
CN116964088A
(zh)
|
2021-01-25 |
2023-10-27 |
里珍纳龙药品有限公司 |
用于治疗肺动脉高压(pah)的抗pdgf-b抗体和使用方法
|
|
WO2022159842A1
(en)
|
2021-01-25 |
2022-07-28 |
Vir Biotechnology, Inc. |
Antibody combination therapies for sars-cov-2 infection
|
|
PE20240761A1
(es)
|
2021-01-28 |
2024-04-17 |
Janssen Biotech Inc |
Proteinas de union a psma y usos de estas
|
|
WO2022173689A1
(en)
|
2021-02-09 |
2022-08-18 |
University Of Georgia Research Foundation, Inc. |
Human monoclonal antibodies against pneumococcal antigens
|
|
JP2024506315A
(ja)
|
2021-02-09 |
2024-02-13 |
ザ ユナイテッド ステイツ オブ アメリカ アズ リプリゼンテッド バイ ザ セクレタリー、デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
コロナウイルスのスパイクタンパク質を標的とする抗体
|
|
TW202246317A
(zh)
|
2021-02-09 |
2022-12-01 |
瑞士商休曼生物醫藥股份公司 |
針對呼吸道融合病毒及其他副黏液病毒的抗體以及使用其之方法
|
|
CA3210069A1
(en)
|
2021-03-03 |
2022-09-09 |
Tong Zhu |
Antibody-drug conjugates comprising an anti-bcma antibody
|
|
EP4301472A1
(en)
|
2021-03-05 |
2024-01-10 |
Dynamicure Biotechnology LLC |
Anti-vista constructs and uses thereof
|
|
WO2022187626A1
(en)
|
2021-03-05 |
2022-09-09 |
Regeneron Pharmaceuticals, Inc. |
Anti-sars-cov-2-variant-spike glycoprotein antibodies and antigen-binding fragments
|
|
WO2022192647A1
(en)
|
2021-03-12 |
2022-09-15 |
Genentech, Inc. |
Anti-klk7 antibodies, anti-klk5 antibodies, multispecific anti-klk5/klk7 antibodies, and methods of use
|
|
KR20230156373A
(ko)
|
2021-03-15 |
2023-11-14 |
제넨테크, 인크. |
루푸스 신염의 치료 조성물 및 치료 방법
|
|
WO2022197947A1
(en)
|
2021-03-18 |
2022-09-22 |
Alector Llc |
Anti-tmem106b antibodies and methods of use thereof
|
|
WO2022197877A1
(en)
|
2021-03-19 |
2022-09-22 |
Genentech, Inc. |
Methods and compositions for time delayed bio-orthogonal release of cytotoxic agents
|
|
WO2022204202A1
(en)
|
2021-03-23 |
2022-09-29 |
Vir Biotechnology, Inc. |
Antibodies that bind to multiple sarbecoviruses
|
|
JP2024511610A
(ja)
|
2021-03-23 |
2024-03-14 |
アレクトル エルエルシー |
コロナウイルス感染の治療及び予防のための抗tmem106b抗体
|
|
TW202304986A
(zh)
|
2021-03-24 |
2023-02-01 |
美商健生生物科技公司 |
靶向cd22及cd79b的抗體
|
|
KR20230160353A
(ko)
|
2021-03-24 |
2023-11-23 |
얀센 바이오테크 인코포레이티드 |
Cd3 항원 결합 도메인을 포함하는 단백질 및 이의 용도
|
|
JP2024511424A
(ja)
|
2021-03-25 |
2024-03-13 |
ダイナミキュア バイオテクノロジー エルエルシー |
抗igfbp7構築物およびその使用
|
|
CN118511853A
(zh)
|
2021-03-31 |
2024-08-20 |
瑞泽恩制药公司 |
包含具有改善的tcrb组库多样性的人源化细胞免疫系统组分的基因修饰的小鼠
|
|
AR125255A1
(es)
|
2021-04-02 |
2023-06-28 |
Regeneron Pharma |
Métodos de predicción y modulación de la glicación de una proteína
|
|
AR125344A1
(es)
|
2021-04-15 |
2023-07-05 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-c1s
|
|
US20240199725A1
(en)
|
2021-04-16 |
2024-06-20 |
Korea University Research And Business Foundation |
Human antibody targeting covid-19 virus
|
|
WO2022225880A1
(en)
|
2021-04-19 |
2022-10-27 |
Genentech, Inc. |
Modified mammalian cells
|
|
KR102871709B1
(ko)
|
2021-04-20 |
2025-10-17 |
리제너론 파마슈티칼스 인코포레이티드 |
아르테민에 대한 인간 항체 및 이의 사용 방법
|
|
AR125398A1
(es)
|
2021-04-22 |
2023-07-12 |
Astellas Pharma Inc |
Anticuerpo biespecífico anti-cldn4 / anti-cd137
|
|
TW202243689A
(zh)
|
2021-04-30 |
2022-11-16 |
瑞士商赫孚孟拉羅股份公司 |
抗cd20/抗cd3雙特異性抗體及抗cd78b抗體藥物結合物的組合治療之給藥
|
|
EP4329800A1
(en)
|
2021-04-30 |
2024-03-06 |
F. Hoffmann-La Roche AG |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibody
|
|
MX2023012974A
(es)
|
2021-05-04 |
2023-11-15 |
Regeneron Pharma |
Agonistas multiespecificos de receptores del fgf21 y sus usos.
|
|
JP2024516996A
(ja)
|
2021-05-05 |
2024-04-18 |
トリアニ・インコーポレイテッド |
トランスジェニック哺乳動物およびその使用方法
|
|
WO2022235867A2
(en)
|
2021-05-06 |
2022-11-10 |
The Rockefeller University |
Neutralizing anti-sars- cov-2 antibodies and methods of use thereof
|
|
AU2022274888A1
(en)
|
2021-05-11 |
2023-12-07 |
Regeneron Pharmaceuticals, Inc. |
Anti-tmprss6 antibodies and uses thereof
|
|
AU2022273063A1
(en)
|
2021-05-12 |
2023-11-23 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
|
WO2022246259A1
(en)
|
2021-05-21 |
2022-11-24 |
Genentech, Inc. |
Modified cells for the production of a recombinant product of interest
|
|
AU2022280767A1
(en)
|
2021-05-24 |
2024-01-18 |
Humabs Biomed Sa |
Engineered polypeptides
|
|
CN113278071B
(zh)
|
2021-05-27 |
2021-12-21 |
江苏荃信生物医药股份有限公司 |
抗人干扰素α受体1单克隆抗体及其应用
|
|
EP4155321A1
(en)
|
2021-06-04 |
2023-03-29 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-ddr2 antibodies and uses thereof
|
|
IL308015A
(en)
|
2021-06-09 |
2023-12-01 |
Hoffmann La Roche |
Combination of a particular braf inhibitor (paradox breaker) and a pd-1 axis binding antagonist for use in the treatment of cancer
|
|
WO2022266221A1
(en)
|
2021-06-16 |
2022-12-22 |
Alector Llc |
Monovalent anti-mertk antibodies and methods of use thereof
|
|
WO2022266223A1
(en)
|
2021-06-16 |
2022-12-22 |
Alector Llc |
Bispecific anti-mertk and anti-pdl1 antibodies and methods of use thereof
|
|
EP4355785A1
(en)
|
2021-06-17 |
2024-04-24 |
Amberstone Biosciences, Inc. |
Anti-cd3 constructs and uses thereof
|
|
JP2024523290A
(ja)
|
2021-06-18 |
2024-06-28 |
ナミ セラピューティクス, インコーポレイテッド |
がんの処置およびその方法における使用のための、マスクされたI型インターフェロン(IFNαおよびIFNβ)を含む融合タンパク質組成物
|
|
JP7472405B2
(ja)
|
2021-06-25 |
2024-04-22 |
中外製薬株式会社 |
抗ctla-4抗体
|
|
TWI864408B
(zh)
|
2021-06-25 |
2024-12-01 |
日商中外製藥股份有限公司 |
抗ctla-4抗體的用途
|
|
US20240316169A1
(en)
|
2021-07-05 |
2024-09-26 |
Regeneron Pharmaceuticals, Inc. |
Utilization of antibodies to shape antibody responses to an antigen
|
|
TW202309097A
(zh)
|
2021-07-14 |
2023-03-01 |
美商建南德克公司 |
抗c-c模體趨化因子受體8(ccr8)抗體及其使用方法
|
|
AU2022311906A1
(en)
|
2021-07-14 |
2024-01-25 |
Regeneron Pharmaceuticals, Inc. |
Anti-sars-cov-2-spike glycoprotein antibodies and antigen-binding fragments
|
|
KR20240036570A
(ko)
|
2021-07-22 |
2024-03-20 |
에프. 호프만-라 로슈 아게 |
이종이량체 Fc 도메인 항체
|
|
JP2024526880A
(ja)
|
2021-07-22 |
2024-07-19 |
ジェネンテック, インコーポレイテッド |
脳標的化組成物及びその使用方法
|
|
MX2024001189A
(es)
|
2021-07-26 |
2024-02-27 |
Sanofi Biotechnology |
Metodos para tratar la urticaria cronica espontanea por administracion de un antagonista de il-4r.
|
|
US20250041433A1
(en)
|
2021-07-28 |
2025-02-06 |
Regeneron Pharmaceuticals, Inc. |
Protein-antiviral compound conjugates
|
|
US20250215103A1
(en)
|
2021-08-03 |
2025-07-03 |
Hoffmann-La Roche Inc. |
Bispecific antibodies and methods of use
|
|
WO2023019239A1
(en)
|
2021-08-13 |
2023-02-16 |
Genentech, Inc. |
Dosing for anti-tryptase antibodies
|
|
AU2022333073A1
(en)
|
2021-08-23 |
2024-04-04 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating atopic dermatitis by administering an il-4r antagonist
|
|
PE20240727A1
(es)
|
2021-08-27 |
2024-04-15 |
Janssen Biotech Inc |
Anticuerpos anti-psma y usos de estos
|
|
JP2024532620A
(ja)
|
2021-08-30 |
2024-09-05 |
ラッセン・セラピューティクス1・インコーポレイテッド |
抗IL-11Rα抗体
|
|
JP2024534853A
(ja)
|
2021-08-30 |
2024-09-26 |
ジェネンテック, インコーポレイテッド |
抗ポリビキチン多重特異性抗体
|
|
WO2023034871A1
(en)
|
2021-09-01 |
2023-03-09 |
Vir Biotechnology, Inc. |
High concentration antibody therapies for sars-cov-2 infection
|
|
CA3230613A1
(en)
|
2021-09-01 |
2023-03-09 |
Daren J. AUSTIN |
Antibody therapies for sars-cov-2 infection in pediatric subjects
|
|
CN113603775B
(zh)
|
2021-09-03 |
2022-05-20 |
江苏荃信生物医药股份有限公司 |
抗人白介素-33单克隆抗体及其应用
|
|
CN113683694B
(zh)
|
2021-09-03 |
2022-05-13 |
江苏荃信生物医药股份有限公司 |
一种抗人tslp单克隆抗体及其应用
|
|
WO2023039442A1
(en)
|
2021-09-08 |
2023-03-16 |
Vir Biotechnology, Inc. |
Broadly neutralizing antibody combination therapies for sars-cov-2 infection
|
|
WO2023046322A1
(en)
|
2021-09-24 |
2023-03-30 |
Janssen Pharmaceutica Nv |
Proteins comprising cd20 binding domains, and uses thereof
|
|
TW202321308A
(zh)
|
2021-09-30 |
2023-06-01 |
美商建南德克公司 |
使用抗tigit抗體、抗cd38抗體及pd—1軸結合拮抗劑治療血液癌症的方法
|
|
EP4408981A1
(en)
|
2021-10-01 |
2024-08-07 |
AbCellera Biologics Inc. |
Transgenic rodents for cell line identification and enrichment
|
|
MX2024004117A
(es)
|
2021-10-08 |
2024-04-19 |
Chugai Pharmaceutical Co Ltd |
Metodo para preparar formulacion de jeringa precargada.
|
|
WO2023062050A1
(en)
|
2021-10-14 |
2023-04-20 |
F. Hoffmann-La Roche Ag |
New interleukin-7 immunoconjugates
|
|
EP4429706A1
(en)
|
2021-10-14 |
2024-09-18 |
F. Hoffmann-La Roche AG |
Alternative pd1-il7v immunoconjugates for the treatment of cancer
|
|
WO2023069919A1
(en)
|
2021-10-19 |
2023-04-27 |
Alector Llc |
Anti-cd300lb antibodies and methods of use thereof
|
|
KR20240099290A
(ko)
|
2021-10-20 |
2024-06-28 |
사노피 바이오테크놀로지 |
Il-4r 길항제를 투여하여 결절성 양진을 치료하는 방법
|
|
CA3235457A1
(en)
|
2021-10-22 |
2023-04-27 |
Regeneron Pharmaceuticals, Inc. |
Factor xi a2 domain-binding antibodies and methods of use thereof
|
|
CN118251491A
(zh)
|
2021-10-28 |
2024-06-25 |
瑞泽恩制药公司 |
用于敲除C5的CRISPR/Cas相关方法及组合物
|
|
WO2022078524A2
(en)
|
2021-11-03 |
2022-04-21 |
Hangzhou Dac Biotech Co., Ltd. |
Specific conjugation of an antibody
|
|
WO2023086815A1
(en)
|
2021-11-10 |
2023-05-19 |
Trianni, Inc. |
Transgenic mammals and methods of use thereof
|
|
EP4430072A1
(en)
|
2021-11-10 |
2024-09-18 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
|
AU2022389969A1
(en)
|
2021-11-16 |
2024-05-02 |
Genentech, Inc. |
Methods and compositions for treating systemic lupus erythematosus (sle) with mosunetuzumab
|
|
US20250011408A1
(en)
|
2021-11-19 |
2025-01-09 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for reducing centralized pain
|
|
WO2023089587A1
(en)
|
2021-11-22 |
2023-05-25 |
Janssen Biotech, Inc. |
Compositions comprising enhanced multispecific binding agents for an immune response
|
|
CN118414166A
(zh)
|
2021-12-01 |
2024-07-30 |
中外制药株式会社 |
含有抗体的制剂的制备方法
|
|
US20230250170A1
(en)
|
2021-12-06 |
2023-08-10 |
Regeneron Pharmaceuticals, Inc. |
Antagonist anti-npr1 antibodies and methods of use thereof
|
|
CN118632622A
(zh)
|
2021-12-08 |
2024-09-10 |
瑞泽恩制药公司 |
突变型肌纤蛋白疾病模型及其用途
|
|
JP2025501522A
(ja)
|
2021-12-17 |
2025-01-22 |
シャンハイ・ヘンリウス・バイオテック・インコーポレイテッド |
抗ox40抗体及び使用方法
|
|
CA3240585A1
(en)
|
2021-12-17 |
2023-06-22 |
Wenfeng Xu |
Anti-ox40 antibodies, multispecific antibodies and methods of use
|
|
WO2023130010A1
(en)
|
2021-12-30 |
2023-07-06 |
Regeneron Pharmaceuticals, Inc. |
Methods for attenuating atopic march by administering an il-4/il-13 antagonist
|
|
US20230287138A1
(en)
|
2022-01-12 |
2023-09-14 |
Regneron Pharmaceuticals, Inc. |
Protein-drug conjugates comprising camptothecin analogs and methods of use thereof
|
|
AU2023208050A1
(en)
|
2022-01-14 |
2024-07-04 |
Regeneron Pharmaceuticals, Inc. |
Verrucarin a derivatives and antibody drug conjugates thereof
|
|
TW202340251A
(zh)
|
2022-01-19 |
2023-10-16 |
美商建南德克公司 |
抗notch2抗體及結合物及其使用方法
|
|
WO2023147399A1
(en)
|
2022-01-27 |
2023-08-03 |
The Rockefeller University |
Broadly neutralizing anti-sars-cov-2 antibodies targeting the n-terminal domain of the spike protein and methods of use thereof
|
|
CN118984837A
(zh)
|
2022-01-28 |
2024-11-19 |
乔治穆内公司 |
作为pd-1激动剂的程序性细胞死亡蛋白1的抗体
|
|
EP4473103A2
(en)
|
2022-02-02 |
2024-12-11 |
Regeneron Pharmaceuticals, Inc. |
Anti-tfr:gaa and anti-cd63:gaa insertions for treatment of pompe disease
|
|
EP4475671A1
(en)
|
2022-02-07 |
2024-12-18 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for defining optimal treatment timeframes in lysosomal disease
|
|
WO2023152581A1
(en)
|
2022-02-09 |
2023-08-17 |
Janssen Biotech, Inc. |
Method of treating cancer with psmaxcd3 antibody
|
|
CN118984836A
(zh)
|
2022-02-10 |
2024-11-19 |
美国政府(由卫生和人类服务部的部长所代表) |
广泛靶向冠状病毒的人单克隆抗体
|
|
EP4476245A1
(en)
|
2022-02-11 |
2024-12-18 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for screening 4r tau targeting agents
|
|
WO2023155902A1
(en)
|
2022-02-18 |
2023-08-24 |
Chongqing Mingdao Haoyue Biotechnology Co., Ltd. |
Intranasal formulations and anti-sars-cov-2-spike protein antibodies
|
|
CA3245693A1
(en)
|
2022-03-10 |
2023-09-14 |
Vivasor, Inc. |
ANTIBODY-DRUG CONJUGATIONS AND THEIR USES
|
|
MX2024011468A
(es)
|
2022-03-23 |
2024-09-25 |
Hoffmann La Roche |
Tratamiento conjunto de un anticuerpo biespecifico anti-cd20/anti-cd3 y quimioterapia.
|
|
JP2025514610A
(ja)
|
2022-03-25 |
2025-05-09 |
シャンハイ・ヘンリウス・バイオテック・インコーポレイテッド |
抗msln抗体及び使用方法
|
|
AU2022450448A1
(en)
|
2022-04-01 |
2024-10-10 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2023201256A1
(en)
|
2022-04-12 |
2023-10-19 |
Vir Biotechnology, Inc. |
High dose antibody therapies for sars-cov-2 infection
|
|
EP4508081A1
(en)
|
2022-04-13 |
2025-02-19 |
F. Hoffmann-La Roche AG |
Pharmaceutical compositions of anti-cd20/anti-cd3 bispecific antibodies and methods of use
|
|
CN119486774A
(zh)
|
2022-04-26 |
2025-02-18 |
中外制药株式会社 |
含有药物制剂的内置过滤器的注射器
|
|
WO2023212586A1
(en)
|
2022-04-27 |
2023-11-02 |
Regeneron Pharmaceuticals, Inc. |
Methods for selecting patients for treatment with an ngf antagonist
|
|
TW202400647A
(zh)
|
2022-04-29 |
2024-01-01 |
美商普瑞諾生物科技公司 |
用於治療嗜酸性球驅動之疾病及病症的方法及組成物
|
|
KR20250006932A
(ko)
|
2022-05-03 |
2025-01-13 |
제넨테크, 인크. |
항-Ly6E 항체, 면역접합체 및 이들의 용도
|
|
WO2023219613A1
(en)
|
2022-05-11 |
2023-11-16 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2023230448A1
(en)
|
2022-05-23 |
2023-11-30 |
Vir Biotechnology, Inc. |
Combination immunotherapy for influenza
|
|
WO2023230445A2
(en)
|
2022-05-23 |
2023-11-30 |
Humabs Biomed Sa |
Broadly neutralizing antibodies against influenza neuraminidase
|
|
WO2023235699A1
(en)
|
2022-05-31 |
2023-12-07 |
Jounce Therapeutics, Inc. |
Antibodies to lilrb4 and uses thereof
|
|
AU2023284422A1
(en)
|
2022-06-07 |
2024-12-19 |
Genentech, Inc. |
Method for determining the efficacy of a lung cancer treatment comprising an anti-pd-l1 antagonist and an anti-tigit antagonist antibody
|
|
WO2023245078A1
(en)
|
2022-06-15 |
2023-12-21 |
Humabs Biomed Sa |
Anti-parvovirus antibodies and uses thereof
|
|
WO2024006472A1
(en)
|
2022-06-30 |
2024-01-04 |
Vir Biotechnology, Inc. |
Antibodies that bind to multiple sarbecoviruses
|
|
TW202421660A
(zh)
|
2022-07-08 |
2024-06-01 |
美商再生元醫藥公司 |
藉由投與il-4r拮抗劑來治療嗜伊紅性食道炎的方法
|
|
EP4554977A1
(en)
|
2022-07-12 |
2025-05-21 |
Regeneron Pharmaceuticals, Inc. |
Antibodies to ciliary neurotrophic factor receptor (cntfr) and methods of use thereof
|
|
AU2023305619A1
(en)
|
2022-07-13 |
2025-01-23 |
F. Hoffmann-La Roche Ag |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
EP4558524A1
(en)
|
2022-07-19 |
2025-05-28 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
KR20250040674A
(ko)
|
2022-07-19 |
2025-03-24 |
리제너론 파마슈티칼스 인코포레이티드 |
유전적으로 변형된 동물 모델 및 인간 면역 시스템을 모델링하는데 있어서 그것의 용도
|
|
CR20250056A
(es)
|
2022-07-22 |
2025-03-19 |
Genentech Inc |
Moléculas de unión al antígeno anti-steap1 y sus usos.
|
|
JP2025526405A
(ja)
|
2022-07-27 |
2025-08-13 |
ヒューマブス・バイオメッド・ソシエテ・アノニム |
Rsv及びmpvパラミクソウイルスに対する広域中和抗体
|
|
WO2024026447A1
(en)
|
2022-07-29 |
2024-02-01 |
Alector Llc |
Anti-gpnmb antibodies and methods of use thereof
|
|
CN120659627A
(zh)
|
2022-07-29 |
2025-09-16 |
瑞泽恩制药公司 |
用于转铁蛋白受体(tfr)介导的脑和肌肉递送的组合物和方法
|
|
AU2023316021A1
(en)
|
2022-07-29 |
2025-03-06 |
Alector Llc |
Cd98hc antigen-binding domains and uses therefor
|
|
CN119497721A
(zh)
|
2022-07-29 |
2025-02-21 |
艾莱克特有限责任公司 |
转铁蛋白受体抗原结合结构域及其用途
|
|
CN120265655A
(zh)
|
2022-07-29 |
2025-07-04 |
瑞泽恩制药公司 |
抗tfr:有效载荷融合物及其使用方法
|
|
EP4565329A1
(en)
|
2022-08-01 |
2025-06-11 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Monoclonal antibodies that bind to the underside of influenza viral neuraminidase
|
|
WO2024044770A1
(en)
|
2022-08-26 |
2024-02-29 |
Core Biotherapeutics, Inc. |
Oligonucleotides for the treatment of breast cancer
|
|
EP4580659A1
(en)
|
2022-08-29 |
2025-07-09 |
Sanofi Biotechnology |
Methods for treating chronic inducible cold urticaria by administering an il-4r antagonist
|
|
CN120153254A
(zh)
|
2022-09-01 |
2025-06-13 |
基因泰克公司 |
膀胱癌的治疗和诊断方法
|
|
WO2024054822A1
(en)
|
2022-09-07 |
2024-03-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Engineered sars-cov-2 antibodies with increased neutralization breadth
|
|
JP2025531788A
(ja)
|
2022-09-07 |
2025-09-25 |
ダイナミキュア バイオテクノロジー エルエルシー |
抗vistaコンストラクト及びその使用
|
|
CN120265314A
(zh)
|
2022-09-28 |
2025-07-04 |
瑞泽恩制药公司 |
抗体抗性修饰受体以增强基于细胞的疗法
|
|
US20240224964A9
(en)
|
2022-09-29 |
2024-07-11 |
Regeneron Pharmaceuticals, Inc. |
Correction of hepatosteatosis in humanized liver animals through restoration of il6/il6r/gp130 signaling in human hepatocytes
|
|
IL319943A
(en)
|
2022-10-07 |
2025-05-01 |
Genentech Inc |
Methods for treating cancer with anti-C motif chemokine receptor 8 (CCR8) antibodies
|
|
WO2024086796A1
(en)
|
2022-10-20 |
2024-04-25 |
Alector Llc |
Anti-ms4a4a antibodies with amyloid-beta therapies
|
|
CN115724975A
(zh)
|
2022-10-20 |
2023-03-03 |
江苏荃信生物医药股份有限公司 |
抗人白介素36受体单克隆抗体及其应用
|
|
EP4609201A1
(en)
|
2022-10-25 |
2025-09-03 |
Genentech, Inc. |
Therapeutic and diagnostic methods for multiple myeloma
|
|
US20240150474A1
(en)
|
2022-10-27 |
2024-05-09 |
Regeneron Pharmaceuticals, Inc. |
Anti-acvri antibodies and their use in the treatment of trauma-induced heterotopic ossification
|
|
WO2024097714A1
(en)
|
2022-11-01 |
2024-05-10 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating hand and foot dermatitis by administering an il-4r antagonist
|
|
CN120051301A
(zh)
|
2022-11-04 |
2025-05-27 |
吉利德科学公司 |
使用抗ccr8抗体、化学疗法和免疫疗法组合的抗癌疗法
|
|
US20240182561A1
(en)
|
2022-11-04 |
2024-06-06 |
Regeneron Pharmaceuticals, Inc. |
Calcium voltage-gated channel auxiliary subunit gamma 1 (cacng1) binding proteins and cacng1-mediated delivery to skeletal muscle
|
|
IL320397A
(en)
|
2022-11-07 |
2025-06-01 |
Regeneron Pharma |
Antibodies binding to the catalytic domain of factor XI and methods of using them
|
|
IL320029A
(en)
|
2022-11-08 |
2025-06-01 |
Genentech Inc |
Compositions and methods for treating childhood idiopathic nephrotic syndrome
|
|
WO2024100170A1
(en)
|
2022-11-11 |
2024-05-16 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a*02/foxp3
|
|
JP2025539938A
(ja)
|
2022-11-14 |
2025-12-10 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
抗fgfr3抗体および抗原結合断片ならびにそれらの使用方法
|
|
JP2025538220A
(ja)
|
2022-11-14 |
2025-11-26 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
アストロサイトへの線維芽細胞増殖因子受容体3媒介送達のための組成物および方法
|
|
WO2024112818A1
(en)
|
2022-11-22 |
2024-05-30 |
Humabs Biomed Sa |
Engineered anti-sars-cov-2 antibodies and uses thereof
|
|
IL320670A
(en)
|
2022-11-23 |
2025-07-01 |
Regeneron Pharma |
Methods for enhancing bone growth by administering an IL-4R antagonist
|
|
TW202440623A
(zh)
|
2022-11-28 |
2024-10-16 |
美商艾洛基因醫療公司 |
靶向密連蛋白18﹒2之嵌合抗原受體及結合劑以及其用途
|
|
WO2024118998A2
(en)
|
2022-12-01 |
2024-06-06 |
Vir Biotechnology, Inc. |
Engineered anti-sars-cov-2 antibodies and methods of using the same
|
|
CN119998314A
(zh)
|
2022-12-08 |
2025-05-13 |
长春百克生物科技股份公司 |
特异性结合rsv的抗体
|
|
JP2025538819A
(ja)
|
2022-12-12 |
2025-11-28 |
ジェネンテック, インコーポレイテッド |
ポリペプチドシアル酸含有量の最適化
|
|
EP4638491A1
(en)
|
2022-12-19 |
2025-10-29 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Monoclonal antibodies for treating sars-cov-2 infection
|
|
KR20250133813A
(ko)
|
2022-12-21 |
2025-09-08 |
리제너론 파마슈티칼스 인코포레이티드 |
Adc 접합을 위한 토포이소머라아제 i 억제제의 전구약물 및 이의 사용 방법
|
|
CN120380024A
(zh)
|
2022-12-21 |
2025-07-25 |
建新公司 |
抗pd-1×4-1bb结合蛋白
|
|
WO2024138155A1
(en)
|
2022-12-22 |
2024-06-27 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Ebolavirus (sudan and zaire) antibodies from non-human primates and human vaccinees
|
|
KR20250133727A
(ko)
|
2023-01-06 |
2025-09-08 |
라센 테라퓨틱스, 인코포레이티드 |
갑상선 안구 질환을 치료하기 위한 항-IL-11Rα 항체
|
|
IL321948A
(en)
|
2023-01-06 |
2025-09-01 |
Lassen Therapeutics Inc |
Anti-IL-18 BP antibodies
|
|
WO2024148241A1
(en)
|
2023-01-06 |
2024-07-11 |
Lassen Therapeutics 1, Inc. |
Anti-il-18bp antibodies
|
|
CN120693345A
(zh)
|
2023-01-06 |
2025-09-23 |
艾利妥 |
抗il18结合蛋白抗体及其使用方法
|
|
EP4649092A1
(en)
|
2023-01-13 |
2025-11-19 |
Regeneron Pharmaceuticals, Inc. |
Fgfr3 binding molecules and methods of use thereof
|
|
PE20252286A1
(es)
|
2023-01-18 |
2025-09-18 |
Genentech Inc |
Anticuerpos multiespecificos y usos de estos
|
|
TWI897189B
(zh)
|
2023-01-18 |
2025-09-11 |
美商基利科學股份有限公司 |
具有經改變重鏈基因座之嵌合基因轉殖免疫球蛋白小鼠及其製造及使用方法
|
|
AU2024209384A1
(en)
|
2023-01-20 |
2025-06-26 |
F. Hoffmann-La Roche Ag |
Recombinant fc domain - il2 variant polypeptides and combination therapy with membrane-anchored antigen binding polypeptides
|
|
AR131856A1
(es)
|
2023-02-16 |
2025-05-07 |
Sanofi Sa |
Proteínas de unión a cd40
|
|
WO2024173876A1
(en)
|
2023-02-17 |
2024-08-22 |
Regeneron Pharmaceuticals, Inc. |
Radiolabeled anti-lag3 antibodies for immuno-pet imaging
|
|
CN120858109A
(zh)
|
2023-03-10 |
2025-10-28 |
基因泰克公司 |
与蛋白酶的融合物及其用途
|
|
CN120958022A
(zh)
|
2023-03-15 |
2025-11-14 |
瑞泽恩制药公司 |
用于获得具有高亲和力的抗体分子的方法
|
|
TW202502819A
(zh)
|
2023-03-22 |
2025-01-16 |
法商賽諾菲生物技術公司 |
藉由投予il-4r拮抗劑治療慢性阻塞性肺病(copd)之方法
|
|
KR20250164835A
(ko)
|
2023-03-27 |
2025-11-25 |
리제너론 파아마슈티컬스, 인크. |
Il-4r 길항제를 투여하여 호산구성 위장염을 치료하는 방법
|
|
CN120936626A
(zh)
|
2023-03-31 |
2025-11-11 |
基因泰克公司 |
抗αvβ8整合素抗体及使用方法
|
|
WO2024211211A1
(en)
|
2023-04-03 |
2024-10-10 |
Regeneron Pharmaceuticals, Inc. |
Methods of improving transplant survival using il-2 receptor gamma chain antibodies
|
|
WO2024211234A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
WO2024211235A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
WO2024211236A2
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
KR20250169612A
(ko)
|
2023-04-10 |
2025-12-03 |
비르 바이오테크놀로지, 인코포레이티드 |
다수의 사르베코바이러스에 결합하는 항체
|
|
WO2024214811A1
(ja)
|
2023-04-14 |
2024-10-17 |
中外製薬株式会社 |
タンパク質含有医薬製剤の安定化方法
|
|
WO2024220546A2
(en)
|
2023-04-17 |
2024-10-24 |
Peak Bio, Inc. |
Antibodies and antibody-drug conjugates and methods of use and synthetic processes and intermediates
|
|
WO2024233341A1
(en)
|
2023-05-05 |
2024-11-14 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
AU2024269754A1
(en)
|
2023-05-08 |
2025-10-23 |
F. Hoffmann-La Roche Ag |
Targeted interferon alpha fusion proteins and methods of use
|
|
AU2024268933A1
(en)
|
2023-05-10 |
2025-11-20 |
Chugai Seiyaku Kabushiki Kaisha |
Methods and compositions for treating cancer
|
|
WO2024238537A1
(en)
|
2023-05-16 |
2024-11-21 |
F. Hoffmann-La Roche Ag |
Pd-1 -regulated il-2 immunocytokine and uses thereof
|
|
WO2024236156A1
(en)
|
2023-05-17 |
2024-11-21 |
Institut National de la Santé et de la Recherche Médicale |
Anti-cathepsin-d antibodies
|
|
WO2024248867A1
(en)
|
2023-05-31 |
2024-12-05 |
Genentech, Inc. |
Methods of treating tgf beta-related disorders with anti-transforming growth factor beta 3 antibodies
|
|
WO2024258743A1
(en)
|
2023-06-13 |
2024-12-19 |
Adcentrx Therapeutics, Inc. |
Methods and compositions related to antibodies and antibody drug conjugates (adcs) that bind nectin-4 proteins
|
|
AU2024304358A1
(en)
|
2023-06-16 |
2025-11-06 |
Regeneron Pharmaceuticals, Inc. |
Vectors, genetically modified cells, and genetically modified non-human animals comprising the same
|
|
WO2024263845A1
(en)
|
2023-06-22 |
2024-12-26 |
Genentech, Inc. |
Treatment of multiple myeloma
|
|
TW202502809A
(zh)
|
2023-06-22 |
2025-01-16 |
美商建南德克公司 |
抗體及其用途
|
|
WO2025010424A1
(en)
|
2023-07-06 |
2025-01-09 |
Vir Biotechnology, Inc. |
Antibodies against staphylococcus antigens and methods of using the same
|
|
WO2025012417A1
(en)
|
2023-07-13 |
2025-01-16 |
Institut National de la Santé et de la Recherche Médicale |
Anti-neurotensin long fragment and anti-neuromedin n long fragment antibodies and uses thereof
|
|
WO2025015321A1
(en)
|
2023-07-13 |
2025-01-16 |
Vir Biotechnology, Inc. |
Broadly neutralizing antibodies against rsv and mpv paramyxoviruses
|
|
WO2025019789A1
(en)
|
2023-07-19 |
2025-01-23 |
Regeneron Pharmaceuticals, Inc. |
ANTI-FACTOR XII/XIIa ANTIBODIES AND USES THEREOF
|
|
US20250049896A1
(en)
|
2023-07-28 |
2025-02-13 |
Regeneron Pharmaceuticals, Inc. |
Anti-tfr:acid sphingomyelinase for treatment of acid sphingomyelinase deficiency
|
|
WO2025029657A2
(en)
|
2023-07-28 |
2025-02-06 |
Regeneron Pharmaceuticals, Inc. |
Anti-tfr:gaa and anti-cd63:gaa insertion for treatment of pompe disease
|
|
US20250136688A1
(en)
|
2023-08-07 |
2025-05-01 |
Janssen Biotech, Inc. |
Stabilized cd3 antigen binding agents and methods of use thereof
|
|
US20250066510A1
(en)
|
2023-08-07 |
2025-02-27 |
Janssen Biotech, Inc. |
Gucy2c antibodies and uses thereof
|
|
WO2025032158A1
(en)
|
2023-08-08 |
2025-02-13 |
Institut National de la Santé et de la Recherche Médicale |
Method to treat tauopathies
|
|
WO2025049591A1
(en)
|
2023-08-28 |
2025-03-06 |
Regeneron Pharmaceuticals, Inc. |
Anti-cxcr4 antibodies and uses thereof
|
|
WO2025049524A1
(en)
|
2023-08-28 |
2025-03-06 |
Regeneron Pharmaceuticals, Inc. |
Cxcr4 antibody-resistant modified receptors
|
|
WO2025045250A1
(en)
|
2023-09-03 |
2025-03-06 |
Kira Pharmaceuticals (Us) Llc |
Anti-human factor d antibody constructs and uses thereof
|
|
WO2025064761A1
(en)
|
2023-09-22 |
2025-03-27 |
Regeneron Pharmaceuticals, Inc. |
Kras10-18 g12d off-target peptides and uses thereof
|
|
WO2025064738A1
(en)
|
2023-09-22 |
2025-03-27 |
Regeneron Pharmaceuticals, Inc. |
Dntt 250-258 off-target peptides and uses thereof
|
|
AR133909A1
(es)
|
2023-09-25 |
2025-11-12 |
Hoffmann La Roche |
ANTICUERPO QUE SE UNE A C3bBb
|
|
WO2025073890A1
(en)
|
2023-10-06 |
2025-04-10 |
Institut National de la Santé et de la Recherche Médicale |
Method to capture circulating tumor extracellular vesicles
|
|
US20250171516A1
(en)
|
2023-11-03 |
2025-05-29 |
Regeneron Pharmaceuticals, Inc. |
Peptide acids as a glp1r agonist and antibody-drug conjugates thereof
|
|
WO2025106474A1
(en)
|
2023-11-14 |
2025-05-22 |
Genentech, Inc. |
Therapeutic and diagnostic methods for treating cancer with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2025113643A1
(en)
|
2023-12-01 |
2025-06-05 |
Gilead Sciences Inc. |
Anti-fap-light fusion protein and use thereof
|
|
WO2025117384A1
(en)
|
2023-12-01 |
2025-06-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Broadly neutralizing influenza hemagglutinin stem-directed antibodies
|
|
WO2025125386A1
(en)
|
2023-12-14 |
2025-06-19 |
F. Hoffmann-La Roche Ag |
Antibodies that bind to folr1 and methods of use
|
|
WO2025133042A2
(en)
|
2023-12-22 |
2025-06-26 |
F. Hoffmann-La Roche Ag |
Activatable fusion proteins and methods of use
|
|
WO2025151806A1
(en)
|
2024-01-11 |
2025-07-17 |
Regeneron Pharmaceuticals, Inc. |
P75 neurotrophin receptor (p75ntr)-binding proteins and p75ntr-mediated delivery to the nervous system
|
|
US20250242056A1
(en)
|
2024-01-26 |
2025-07-31 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for using plasma cell depleting agents and/or b cell depleting agents to suppress host anti-aav antibody response and enable aav transduction and re-dosing
|
|
WO2025165851A1
(en)
|
2024-01-30 |
2025-08-07 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating allergy using anti-bet v 1 antibodies
|
|
WO2025166045A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
β-GLUCOCEREBROSIDASE ENZYMES, FUSION PROTEINS AND COMPLEXES COMPRISING THE SAME, AND METHODS OF USE THEREOF
|
|
WO2025166040A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Multi-specific binding proteins that bind to gpnmb and a blood brain barrier target and methods of use thereof
|
|
WO2025166042A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Cd98hc antigen-binding domains and uses therefor
|
|
WO2025166077A1
(en)
|
2024-01-31 |
2025-08-07 |
Alector Llc |
Compositions comprising progranulin and uses thereof
|
|
US20250255282A1
(en)
|
2024-02-08 |
2025-08-14 |
Regeneron Pharmaceuticals, Inc. |
Vectors, genetically modified cells, and genetically modified non-human animals comprising the same
|
|
WO2025171411A1
(en)
|
2024-02-09 |
2025-08-14 |
Herophilus, Inc. |
Compositions and methods related to modulating macrophage migration inhibitory factor (mif)-cd74 signaling and related treatments for neuroinflammatory conditions
|
|
WO2025179282A1
(en)
|
2024-02-23 |
2025-08-28 |
Flatiron Bio, Llc |
Antibodies targeting epstein-barr virus proteins and methods of use
|
|
WO2025194126A1
(en)
|
2024-03-15 |
2025-09-18 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Respiratory syncytial virus (rsv) g and f antibodies with high rsv-neutralizing potency
|
|
WO2025196639A1
(en)
|
2024-03-21 |
2025-09-25 |
Seagen Inc. |
Cd25 antibodies, antibody-drug conjugates, and uses thereof
|
|
WO2025202147A1
(en)
|
2024-03-27 |
2025-10-02 |
F. Hoffmann-La Roche Ag |
Interleukin-7 immunoconjugates
|
|
WO2025221640A1
(en)
|
2024-04-15 |
2025-10-23 |
Sanofi Biotechnology |
Methods for treating chronic rhinosinusitis without nasal polyps by administering an il-4r antagonist
|
|
WO2025226808A1
(en)
|
2024-04-24 |
2025-10-30 |
Genentech, Inc. |
Compositions and methods of treating lupus nephritis
|
|
WO2025224297A1
(en)
|
2024-04-26 |
2025-10-30 |
Institut National de la Santé et de la Recherche Médicale |
Antibodies having specificity to tgfbi and uses thereof
|
|
WO2025235388A1
(en)
|
2024-05-06 |
2025-11-13 |
Regeneron Pharmaceuticals, Inc. |
Transgene genomic identification by nuclease-mediated long read sequencing
|
|
WO2025240335A1
(en)
|
2024-05-13 |
2025-11-20 |
Regeneron Pharmaceuticals, Inc. |
Fgfr3 binding molecules and methods of use thereof
|
|
WO2025250495A1
(en)
|
2024-05-28 |
2025-12-04 |
Regeneron Pharmaceuticals, Inc. |
Acceleration of human hepatocyte engraftment in humanized liver animals by supplementing paracrine ligands or agonists that activate human liver regeneration signals
|
|
WO2025259871A1
(en)
|
2024-06-14 |
2025-12-18 |
Gilead Sciences, Inc. |
Anti-ccr8 antibodies and uses thereof
|