EA025962B1 - АНТИТЕЛА, ОБЛАДАЮЩИЕ ПОВЫШЕННОЙ АФФИННОСТЬЮ К СВЯЗЫВАНИЮ С Fc-РЕЦЕПТОРОМ И ЭФФЕКТОРНОЙ ФУНКЦИЕЙ - Google Patents
АНТИТЕЛА, ОБЛАДАЮЩИЕ ПОВЫШЕННОЙ АФФИННОСТЬЮ К СВЯЗЫВАНИЮ С Fc-РЕЦЕПТОРОМ И ЭФФЕКТОРНОЙ ФУНКЦИЕЙ Download PDFInfo
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- EA025962B1 EA025962B1 EA201100128A EA201100128A EA025962B1 EA 025962 B1 EA025962 B1 EA 025962B1 EA 201100128 A EA201100128 A EA 201100128A EA 201100128 A EA201100128 A EA 201100128A EA 025962 B1 EA025962 B1 EA 025962B1
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| EA200600905A EA015009B1 (ru) | 2003-11-05 | 2004-11-05 | АНТИГЕНСВЯЗЫВАЮЩИЕ МОЛЕКУЛЫ, ОБЛАДАЮЩИЕ ПОВЫШЕННОЙ АФФИННОСТЬЮ К СВЯЗЫВАНИЮ С Fc-РЕЦЕПТОРОМ И ЭФФЕКТОРНОЙ ФУНКЦИЕЙ |
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- 2022-08-24 US US17/822,105 patent/US20230212303A1/en not_active Abandoned
- 2022-08-24 NO NO20220904A patent/NO347800B1/no unknown
-
2023
- 2023-12-14 US US18/540,730 patent/US20240301079A1/en active Pending
Patent Citations (3)
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|---|---|---|---|---|
| WO2000067796A1 (en) * | 1999-05-07 | 2000-11-16 | Genentech, Inc. | Treatment of autoimmune diseases with antagonists which bind to b cell surface markers |
| US20030003097A1 (en) * | 2001-04-02 | 2003-01-02 | Idec Pharmaceutical Corporation | Recombinant antibodies coexpressed with GnTIII |
| WO2003011878A2 (en) * | 2001-08-03 | 2003-02-13 | Glycart Biotechnology Ag | Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity |
Non-Patent Citations (3)
| Title |
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| CRAGG M S,ET AL: "Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts.", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 101, no. 3, 1 February 2003 (2003-02-01), US, pages 1045 - 1052, XP002329935, ISSN: 0006-4971, DOI: 10.1182/blood-2002-06-1761 * |
| DAVIES J ET AL: "Expression of GnTIII in a recombinant anti-CD20 CHO production cell line: Expression of antibodies with altered glycoforms leads to an increase in ADCC through higher affinity for FC gamma RIII.", BIOTECHNOLOGY AND BIOENGINEERING - COMBINATORIAL CHEMISTRY., WILEY, NEW YORK, NY., US, vol. 74, no. 4, 20 August 2001 (2001-08-20), US, pages 288 - 294, XP002285964, DOI: 10.1002/bit.1119 * |
| POLYAK MARIA J ET AL: "Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 99, no. 9, 1 May 2002 (2002-05-01), US, pages 3256 - 3262, XP002308044, ISSN: 0006-4971, DOI: 10.1182/blood.V99.9.3256 * |
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