US2008526A
(en)
|
1932-11-03 |
1935-07-16 |
Wappler Frederick Charles |
Method and means for treating living tissue
|
US2103001A
(en)
|
1933-08-28 |
1937-12-21 |
E S Evans And Sons |
Windshield wiper mechanism
|
US3467096A
(en)
|
1966-04-12 |
1969-09-16 |
Ferrell S Horn |
Multiple hypodermic syringe arrangement
|
BE757653A
(en)
|
1969-10-21 |
1971-04-16 |
Ugine Kuhlmann |
NEW DRUGS DERIVED FROM NUCLEIC ACIDS AND METHODS FOR THEIR PREPARATION
|
US3872171A
(en)
|
1971-05-24 |
1975-03-18 |
Pfizer |
Polyamines as antiviral agents in animals
|
BE786542A
(en)
|
1971-07-22 |
1973-01-22 |
Dow Corning |
SUCTION DEVICE ALLOWING TO OBTAIN CELL SAMPLES
|
US3906092A
(en)
|
1971-11-26 |
1975-09-16 |
Merck & Co Inc |
Stimulation of antibody response
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US5132418A
(en)
|
1980-02-29 |
1992-07-21 |
University Patents, Inc. |
Process for preparing polynucleotides
|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
US4500707A
(en)
|
1980-02-29 |
1985-02-19 |
University Patents, Inc. |
Nucleosides useful in the preparation of polynucleotides
|
US4411657A
(en)
|
1980-05-19 |
1983-10-25 |
Anibal Galindo |
Hypodermic needle
|
US4415732A
(en)
|
1981-03-27 |
1983-11-15 |
University Patents, Inc. |
Phosphoramidite compounds and processes
|
US4973679A
(en)
|
1981-03-27 |
1990-11-27 |
University Patents, Inc. |
Process for oligonucleo tide synthesis using phosphormidite intermediates
|
US4668777A
(en)
|
1981-03-27 |
1987-05-26 |
University Patents, Inc. |
Phosphoramidite nucleoside compounds
|
US4401796A
(en)
|
1981-04-30 |
1983-08-30 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
US4373071A
(en)
|
1981-04-30 |
1983-02-08 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
US4474569A
(en)
|
1982-06-28 |
1984-10-02 |
Denver Surgical Developments, Inc. |
Antenatal shunt
|
JPS5927900A
(en)
|
1982-08-09 |
1984-02-14 |
Wakunaga Seiyaku Kk |
Oligonucleotide derivative and its preparation
|
US4737462A
(en)
|
1982-10-19 |
1988-04-12 |
Cetus Corporation |
Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
|
US4588585A
(en)
|
1982-10-19 |
1986-05-13 |
Cetus Corporation |
Human recombinant cysteine depleted interferon-β muteins
|
FR2540122B1
(en)
|
1983-01-27 |
1985-11-29 |
Centre Nat Rech Scient |
NOVEL COMPOUNDS COMPRISING A SEQUENCE OF OLIGONUCLEOTIDE LINKED TO AN INTERCALATION AGENT, THEIR SYNTHESIS PROCESS AND THEIR APPLICATION
|
US4605735A
(en)
|
1983-02-14 |
1986-08-12 |
Wakunaga Seiyaku Kabushiki Kaisha |
Oligonucleotide derivatives
|
US4948882A
(en)
|
1983-02-22 |
1990-08-14 |
Syngene, Inc. |
Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
|
US4824941A
(en)
|
1983-03-10 |
1989-04-25 |
Julian Gordon |
Specific antibody to the native form of 2'5'-oligonucleotides, the method of preparation and the use as reagents in immunoassays or for binding 2'5'-oligonucleotides in biological systems
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4587044A
(en)
|
1983-09-01 |
1986-05-06 |
The Johns Hopkins University |
Linkage of proteins to nucleic acids
|
US5118800A
(en)
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
Oligonucleotides possessing a primary amino group in the terminal nucleotide
|
US5118802A
(en)
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside
|
US4579849A
(en)
|
1984-04-06 |
1986-04-01 |
Merck & Co., Inc. |
N-alkylguanine acyclonucleosides as antiviral agents
|
US4957735A
(en)
|
1984-06-12 |
1990-09-18 |
The University Of Tennessee Research Corporation |
Target-sensitive immunoliposomes- preparation and characterization
|
FR2567892B1
(en)
|
1984-07-19 |
1989-02-17 |
Centre Nat Rech Scient |
NOVEL OLIGONUCLEOTIDES, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS AS MEDIATORS IN DEVELOPING THE EFFECTS OF INTERFERONS
|
US5258506A
(en)
|
1984-10-16 |
1993-11-02 |
Chiron Corporation |
Photolabile reagents for incorporation into oligonucleotide chains
|
US5430136A
(en)
|
1984-10-16 |
1995-07-04 |
Chiron Corporation |
Oligonucleotides having selectably cleavable and/or abasic sites
|
US4828979A
(en)
|
1984-11-08 |
1989-05-09 |
Life Technologies, Inc. |
Nucleotide analogs for nucleic acid labeling and detection
|
US4959314A
(en)
|
1984-11-09 |
1990-09-25 |
Cetus Corporation |
Cysteine-depleted muteins of biologically active proteins
|
US5036006A
(en)
|
1984-11-13 |
1991-07-30 |
Cornell Research Foundation, Inc. |
Method for transporting substances into living cells and tissues and apparatus therefor
|
US5116943A
(en)
|
1985-01-18 |
1992-05-26 |
Cetus Corporation |
Oxidation-resistant muteins of Il-2 and other protein
|
CA1288073C
(en)
|
1985-03-07 |
1991-08-27 |
Paul G. Ahlquist |
Rna transformation vector
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
EP0204401A1
(en)
|
1985-04-09 |
1986-12-10 |
Biogen, Inc. |
Method of improving the yield of polypeptides produced in a host cell by stabilizing mRNA
|
US4762779A
(en)
|
1985-06-13 |
1988-08-09 |
Amgen Inc. |
Compositions and methods for functionalizing nucleic acids
|
US5017691A
(en)
|
1986-07-03 |
1991-05-21 |
Schering Corporation |
Mammalian interleukin-4
|
CA1335429C
(en)
|
1986-03-07 |
1995-05-02 |
Geoffrey L. Smith |
Processes for the production of hcmv glycoproteins, antibodies thereto and hcmv vaccines, and recombinant vectors therefor
|
US5317098A
(en)
|
1986-03-17 |
1994-05-31 |
Hiroaki Shizuya |
Non-radioisotope tagging of fragments
|
US5153319A
(en)
|
1986-03-31 |
1992-10-06 |
University Patents, Inc. |
Process for preparing polynucleotides
|
US4879111A
(en)
|
1986-04-17 |
1989-11-07 |
Cetus Corporation |
Treatment of infections with lymphokines
|
JPS638396A
(en)
|
1986-06-30 |
1988-01-14 |
Wakunaga Pharmaceut Co Ltd |
Poly-labeled oligonucleotide derivative
|
US4904582A
(en)
|
1987-06-11 |
1990-02-27 |
Synthetic Genetics |
Novel amphiphilic nucleic acid conjugates
|
US6090591A
(en)
|
1987-07-31 |
2000-07-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Selective amplification of target polynucleotide sequences
|
CA1340843C
(en)
|
1987-07-31 |
1999-12-07 |
J. Lawrence Burg |
Selective amplification of target polynucleotide sequences
|
US5585481A
(en)
|
1987-09-21 |
1996-12-17 |
Gen-Probe Incorporated |
Linking reagents for nucleotide probes
|
US5525465A
(en)
|
1987-10-28 |
1996-06-11 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Oligonucleotide-polyamide conjugates and methods of production and applications of the same
|
DE3738460A1
(en)
|
1987-11-12 |
1989-05-24 |
Max Planck Gesellschaft |
MODIFIED OLIGONUCLEOTIDS
|
CA1327358C
(en)
|
1987-11-17 |
1994-03-01 |
Morio Fujiu |
Fluoro cytidine derivatives
|
US5563250A
(en)
|
1987-12-02 |
1996-10-08 |
Neorx Corporation |
Cleavable conjugates for the delivery and release of agents in native form
|
DE68908054T2
(en)
|
1988-01-21 |
1994-03-10 |
Genentech Inc |
REINFORCEMENT AND DETECTION OF NUCLEIC ACID SEQUENCES.
|
CA1340807C
(en)
|
1988-02-24 |
1999-11-02 |
Lawrence T. Malek |
Nucleic acid amplification process
|
JP2650159B2
(en)
|
1988-02-24 |
1997-09-03 |
アクゾ・ノベル・エヌ・ベー |
Nucleic acid amplification method
|
US5082830A
(en)
|
1988-02-26 |
1992-01-21 |
Enzo Biochem, Inc. |
End labeled nucleotide probe
|
WO1989007947A1
(en)
|
1988-03-04 |
1989-09-08 |
Cancer Research Campaign Technology Limited |
Improvements relating to antigens
|
EP0362371A4
(en)
|
1988-04-15 |
1990-10-24 |
Protein Design Labs, Inc. |
Il-2 receptor-specific chimeric antibodies
|
US5109124A
(en)
|
1988-06-01 |
1992-04-28 |
Biogen, Inc. |
Nucleic acid probe linked to a label having a terminal cysteine
|
US5021335A
(en)
|
1988-06-17 |
1991-06-04 |
The Board Of Trustees Of The Leland Stanford Junior University |
In situ transcription in cells and tissues
|
US5168038A
(en)
|
1988-06-17 |
1992-12-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
In situ transcription in cells and tissues
|
US5130238A
(en)
|
1988-06-24 |
1992-07-14 |
Cangene Corporation |
Enhanced nucleic acid amplification process
|
US5262536A
(en)
|
1988-09-15 |
1993-11-16 |
E. I. Du Pont De Nemours And Company |
Reagents for the preparation of 5'-tagged oligonucleotides
|
US5759802A
(en)
|
1988-10-26 |
1998-06-02 |
Tonen Corporation |
Production of human serum alubumin A
|
US5512439A
(en)
|
1988-11-21 |
1996-04-30 |
Dynal As |
Oligonucleotide-linked magnetic particles and uses thereof
|
US5047524A
(en)
|
1988-12-21 |
1991-09-10 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
US5262530A
(en)
|
1988-12-21 |
1993-11-16 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US5599923A
(en)
|
1989-03-06 |
1997-02-04 |
Board Of Regents, University Of Tx |
Texaphyrin metal complexes having improved functionalization
|
US5457183A
(en)
|
1989-03-06 |
1995-10-10 |
Board Of Regents, The University Of Texas System |
Hydroxylated texaphyrins
|
EP1026253B2
(en)
|
1989-03-21 |
2012-12-19 |
Vical Incorporated |
Expression of exogenous polynucleotide sequences in a vertebrate
|
US5693622A
(en)
|
1989-03-21 |
1997-12-02 |
Vical Incorporated |
Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
|
US6214804B1
(en)
|
1989-03-21 |
2001-04-10 |
Vical Incorporated |
Induction of a protective immune response in a mammal by injecting a DNA sequence
|
US6867195B1
(en)
|
1989-03-21 |
2005-03-15 |
Vical Incorporated |
Lipid-mediated polynucleotide administration to reduce likelihood of subject's becoming infected
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
US6673776B1
(en)
|
1989-03-21 |
2004-01-06 |
Vical Incorporated |
Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human
|
US5012818A
(en)
|
1989-05-04 |
1991-05-07 |
Joishy Suresh K |
Two in one bone marrow surgical needle
|
IE66597B1
(en)
|
1989-05-10 |
1996-01-24 |
Akzo Nv |
Method for the synthesis of ribonucleic acid (RNA)
|
US5332671A
(en)
|
1989-05-12 |
1994-07-26 |
Genetech, Inc. |
Production of vascular endothelial cell growth factor and DNA encoding same
|
US5240855A
(en)
|
1989-05-12 |
1993-08-31 |
Pioneer Hi-Bred International, Inc. |
Particle gun
|
US5391723A
(en)
|
1989-05-31 |
1995-02-21 |
Neorx Corporation |
Oligonucleotide conjugates
|
US4958013A
(en)
|
1989-06-06 |
1990-09-18 |
Northwestern University |
Cholesteryl modified oligonucleotides
|
CA2020958C
(en)
|
1989-07-11 |
2005-01-11 |
Daniel L. Kacian |
Nucleic acid sequence amplification methods
|
US5451463A
(en)
|
1989-08-28 |
1995-09-19 |
Clontech Laboratories, Inc. |
Non-nucleoside 1,3-diol reagents for labeling synthetic oligonucleotides
|
US5254469A
(en)
|
1989-09-12 |
1993-10-19 |
Eastman Kodak Company |
Oligonucleotide-enzyme conjugate that can be used as a probe in hybridization assays and polymerase chain reaction procedures
|
US5591722A
(en)
|
1989-09-15 |
1997-01-07 |
Southern Research Institute |
2'-deoxy-4'-thioribonucleosides and their antiviral activity
|
US5545522A
(en)
|
1989-09-22 |
1996-08-13 |
Van Gelder; Russell N. |
Process for amplifying a target polynucleotide sequence using a single primer-promoter complex
|
WO1991006556A1
(en)
|
1989-10-24 |
1991-05-16 |
Gilead Sciences, Inc. |
2' modified oligonucleotides
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
NO904633L
(en)
|
1989-11-09 |
1991-05-10 |
Molecular Diagnostics Inc |
AMPLIFICATION OF NUCLEIC ACIDS BY TRANSCRIPABLE HAIRNEL PROBE.
|
US5215899A
(en)
|
1989-11-09 |
1993-06-01 |
Miles Inc. |
Nucleic acid amplification employing ligatable hairpin probe and transcription
|
US5292873A
(en)
|
1989-11-29 |
1994-03-08 |
The Research Foundation Of State University Of New York |
Nucleic acids labeled with naphthoquinone probe
|
US5633076A
(en)
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
US5697901A
(en)
|
1989-12-14 |
1997-12-16 |
Elof Eriksson |
Gene delivery by microneedle injection
|
US5486603A
(en)
|
1990-01-08 |
1996-01-23 |
Gilead Sciences, Inc. |
Oligonucleotide having enhanced binding affinity
|
US7037646B1
(en)
|
1990-01-11 |
2006-05-02 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
US5646265A
(en)
|
1990-01-11 |
1997-07-08 |
Isis Pharmceuticals, Inc. |
Process for the preparation of 2'-O-alkyl purine phosphoramidites
|
US6783931B1
(en)
|
1990-01-11 |
2004-08-31 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
US5670633A
(en)
|
1990-01-11 |
1997-09-23 |
Isis Pharmaceuticals, Inc. |
Sugar modified oligonucleotides that detect and modulate gene expression
|
US5578718A
(en)
|
1990-01-11 |
1996-11-26 |
Isis Pharmaceuticals, Inc. |
Thiol-derivatized nucleosides
|
US5214136A
(en)
|
1990-02-20 |
1993-05-25 |
Gilead Sciences, Inc. |
Anthraquinone-derivatives oligonucleotides
|
AU7579991A
(en)
|
1990-02-20 |
1991-09-18 |
Gilead Sciences, Inc. |
Pseudonucleosides and pseudonucleotides and their polymers
|
GB9009980D0
(en)
|
1990-05-03 |
1990-06-27 |
Amersham Int Plc |
Phosphoramidite derivatives,their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides
|
DE69032425T2
(en)
|
1990-05-11 |
1998-11-26 |
Microprobe Corp., Bothell, Wash. |
Immersion test strips for nucleic acid hybridization assays and methods for covalently immobilizing oligonucleotides
|
US5194370A
(en)
|
1990-05-16 |
1993-03-16 |
Life Technologies, Inc. |
Promoter ligation activated transcription amplification of nucleic acid sequences
|
EP0542874A4
(en)
|
1990-07-25 |
1994-05-11 |
Syngene Inc |
Circular extension for generating multiple nucleic acid complements
|
US5489677A
(en)
|
1990-07-27 |
1996-02-06 |
Isis Pharmaceuticals, Inc. |
Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
|
US5218105A
(en)
|
1990-07-27 |
1993-06-08 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
US5608046A
(en)
|
1990-07-27 |
1997-03-04 |
Isis Pharmaceuticals, Inc. |
Conjugated 4'-desmethyl nucleoside analog compounds
|
US5138045A
(en)
|
1990-07-27 |
1992-08-11 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
US5688941A
(en)
|
1990-07-27 |
1997-11-18 |
Isis Pharmaceuticals, Inc. |
Methods of making conjugated 4' desmethyl nucleoside analog compounds
|
US5245022A
(en)
|
1990-08-03 |
1993-09-14 |
Sterling Drug, Inc. |
Exonuclease resistant terminally substituted oligonucleotides
|
US5512667A
(en)
|
1990-08-28 |
1996-04-30 |
Reed; Michael W. |
Trifunctional intermediates for preparing 3'-tailed oligonucleotides
|
US6140496A
(en)
|
1990-10-09 |
2000-10-31 |
Benner; Steven Albert |
Precursors for deoxyribonucleotides containing non-standard nucleosides
|
WO1992008728A1
(en)
|
1990-11-08 |
1992-05-29 |
Hybridon, Inc. |
Incorporation of multiple reporter groups on synthetic oligonucleotides
|
US5527288A
(en)
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
US6100024A
(en)
|
1991-02-08 |
2000-08-08 |
Promega Corporation |
Methods and compositions for nucleic acid detection by target extension and probe amplification
|
EP0610201B2
(en)
|
1991-03-18 |
2007-09-26 |
New York University |
Monoclonal and chimeric antibodies specific for human tumor necrosis factor
|
US5426180A
(en)
|
1991-03-27 |
1995-06-20 |
Research Corporation Technologies, Inc. |
Methods of making single-stranded circular oligonucleotides
|
WO1992019759A1
(en)
|
1991-04-25 |
1992-11-12 |
Chugai Seiyaku Kabushiki Kaisha |
Reconstituted human antibody against human interleukin 6 receptor
|
FR2676072B1
(en)
|
1991-05-03 |
1994-11-18 |
Transgene Sa |
RNA DELIVERY VECTOR.
|
US5714331A
(en)
|
1991-05-24 |
1998-02-03 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
|
US5719262A
(en)
|
1993-11-22 |
1998-02-17 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having amino acid side chains
|
US5539082A
(en)
|
1993-04-26 |
1996-07-23 |
Nielsen; Peter E. |
Peptide nucleic acids
|
US5169766A
(en)
|
1991-06-14 |
1992-12-08 |
Life Technologies, Inc. |
Amplification of nucleic acid molecules
|
US5371241A
(en)
|
1991-07-19 |
1994-12-06 |
Pharmacia P-L Biochemicals Inc. |
Fluorescein labelled phosphoramidites
|
US5199441A
(en)
|
1991-08-20 |
1993-04-06 |
Hogle Hugh H |
Fine needle aspiration biopsy apparatus and method
|
ES2103918T3
(en)
|
1991-10-17 |
1997-10-01 |
Ciba Geigy Ag |
BICYCLE NUCLEOSIDES, OLIGONUCLEOTIDES, PROCEDURE FOR THEIR OBTAINING AND INTERMEDIATE PRODUCTS.
|
US5298422A
(en)
|
1991-11-06 |
1994-03-29 |
Baylor College Of Medicine |
Myogenic vector systems
|
US5359044A
(en)
|
1991-12-13 |
1994-10-25 |
Isis Pharmaceuticals |
Cyclobutyl oligonucleotide surrogates
|
US5824307A
(en)
|
1991-12-23 |
1998-10-20 |
Medimmune, Inc. |
Human-murine chimeric antibodies against respiratory syncytial virus
|
US5595726A
(en)
|
1992-01-21 |
1997-01-21 |
Pharmacyclics, Inc. |
Chromophore probe for detection of nucleic acid
|
US5565552A
(en)
|
1992-01-21 |
1996-10-15 |
Pharmacyclics, Inc. |
Method of expanded porphyrin-oligonucleotide conjugate synthesis
|
EP0625049A4
(en)
|
1992-01-23 |
1995-07-12 |
Vical Inc |
Ex vivo gene transfer.
|
FR2687679B1
(en)
|
1992-02-05 |
1994-10-28 |
Centre Nat Rech Scient |
OLIGOTHIONUCLEOTIDES.
|
JP3368603B2
(en)
|
1992-02-28 |
2003-01-20 |
オリンパス光学工業株式会社 |
Gene therapy treatment device
|
CA2076465C
(en)
|
1992-03-25 |
2002-11-26 |
Ravi V. J. Chari |
Cell binding agent conjugates of analogues and derivatives of cc-1065
|
US6174666B1
(en)
|
1992-03-27 |
2001-01-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Method of eliminating inhibitory/instability regions from mRNA
|
US6132419A
(en)
|
1992-05-22 |
2000-10-17 |
Genetronics, Inc. |
Electroporetic gene and drug therapy
|
US5514545A
(en)
|
1992-06-11 |
1996-05-07 |
Trustees Of The University Of Pennsylvania |
Method for characterizing single cells based on RNA amplification for diagnostics and therapeutics
|
US5505931A
(en)
|
1993-03-04 |
1996-04-09 |
The Dow Chemical Company |
Acid cleavable compounds, their preparation and use as bifunctional acid-labile crosslinking agents
|
EP0577558A2
(en)
|
1992-07-01 |
1994-01-05 |
Ciba-Geigy Ag |
Carbocyclic nucleosides having bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates
|
US5272250A
(en)
|
1992-07-10 |
1993-12-21 |
Spielvogel Bernard F |
Boronated phosphoramidate compounds
|
US6670178B1
(en)
|
1992-07-10 |
2003-12-30 |
Transkaryotic Therapies, Inc. |
In Vivo production and delivery of insulinotropin for gene therapy
|
DK0652973T3
(en)
|
1992-07-31 |
1997-09-15 |
Behringwerke Ag |
Method for inserting defined sequences at the 3-end of polynucleotides
|
US5273525A
(en)
|
1992-08-13 |
1993-12-28 |
Btx Inc. |
Injection and electroporation apparatus for drug and gene delivery
|
US5240885A
(en)
|
1992-09-21 |
1993-08-31 |
Corning Incorporated |
Rare earth-doped, stabilized cadmium halide glasses
|
AU5665694A
(en)
|
1992-11-04 |
1994-05-24 |
Denver Biomaterials Inc. |
Apparatus for removal of pleural effusion fluid
|
EP0752248B1
(en)
|
1992-11-13 |
2000-09-27 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
US5736137A
(en)
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
US5574142A
(en)
|
1992-12-15 |
1996-11-12 |
Microprobe Corporation |
Peptide linkers for improved oligonucleotide delivery
|
DE69419721T2
(en)
|
1993-01-12 |
2000-04-27 |
Biogen Inc |
RECOMBINANT ANTI-VLA4 ANTIBODY MOLECULES
|
FR2703253B1
(en)
|
1993-03-30 |
1995-06-23 |
Centre Nat Rech Scient |
APPLICATOR OF ELECTRIC PULSES FOR TREATING BIOLOGICAL TISSUES.
|
AU6449394A
(en)
|
1993-03-30 |
1994-10-24 |
Sterling Winthrop Inc. |
Acyclic nucleoside analogs and oligonucleotide sequences containing them
|
DE4311944A1
(en)
|
1993-04-10 |
1994-10-13 |
Degussa |
Coated sodium percarbonate particles, process for their preparation and detergent, cleaning and bleaching compositions containing them
|
US7135312B2
(en)
|
1993-04-15 |
2006-11-14 |
University Of Rochester |
Circular DNA vectors for synthesis of RNA and DNA
|
US5773244A
(en)
|
1993-05-19 |
1998-06-30 |
Regents Of The University Of California |
Methods of making circular RNA
|
US6541498B2
(en)
|
1993-05-20 |
2003-04-01 |
Texas Biotechnology |
Benzenesulfonamides and the use thereof to modulate the activity of endothelin
|
US5851829A
(en)
|
1993-07-16 |
1998-12-22 |
Dana-Farber Cancer Institute |
Method of intracellular binding of target molecules
|
US6294664B1
(en)
|
1993-07-29 |
2001-09-25 |
Isis Pharmaceuticals, Inc. |
Synthesis of oligonucleotides
|
US5672491A
(en)
|
1993-09-20 |
1997-09-30 |
The Leland Stanford Junior University |
Recombinant production of novel polyketides
|
US6432711B1
(en)
|
1993-11-03 |
2002-08-13 |
Diacrin, Inc. |
Embryonic stem cells capable of differentiating into desired cell lines
|
US6096503A
(en)
|
1993-11-12 |
2000-08-01 |
The Scripps Research Institute |
Method for simultaneous identification of differentially expresses mRNAs and measurement of relative concentrations
|
US5446137B1
(en)
|
1993-12-09 |
1998-10-06 |
Behringwerke Ag |
Oligonucleotides containing 4'-substituted nucleotides
|
US5519134A
(en)
|
1994-01-11 |
1996-05-21 |
Isis Pharmaceuticals, Inc. |
Pyrrolidine-containing monomers and oligomers
|
US5840299A
(en)
|
1994-01-25 |
1998-11-24 |
Athena Neurosciences, Inc. |
Humanized antibodies against leukocyte adhesion molecule VLA-4
|
US7435802B2
(en)
|
1994-01-25 |
2008-10-14 |
Elan Pharaceuticals, Inc. |
Humanized anti-VLA4 immunoglobulins
|
DE69533295T3
(en)
|
1994-02-16 |
2009-07-16 |
The Government Of The United States Of America, As Represented By The Secretary, The Department Of Health And Human Services |
Melanoma-associated antigens, epitopes thereof and melanoma-containing vaccines
|
IL112820A0
(en)
|
1994-03-07 |
1995-05-26 |
Merck & Co Inc |
Coordinate in vivo gene expression
|
US5965720A
(en)
|
1994-03-18 |
1999-10-12 |
Lynx Therapeutics, Inc. |
Oligonucleotide N3'→P5' phosphoramidates
|
EP0752005B1
(en)
|
1994-03-23 |
2008-10-08 |
Ohio University |
Compacted nucleic acids and their delivery to cells
|
US5807861A
(en)
|
1994-03-24 |
1998-09-15 |
Cell Therapeutics, Inc. |
Amine substituted xanthinyl compounds
|
US5457041A
(en)
|
1994-03-25 |
1995-10-10 |
Science Applications International Corporation |
Needle array and method of introducing biological substances into living cells using the needle array
|
WO1995026204A1
(en)
|
1994-03-25 |
1995-10-05 |
Isis Pharmaceuticals, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
US5627053A
(en)
|
1994-03-29 |
1997-05-06 |
Ribozyme Pharmaceuticals, Inc. |
2'deoxy-2'-alkylnucleotide containing nucleic acid
|
US6074642A
(en)
|
1994-05-02 |
2000-06-13 |
Alexion Pharmaceuticals, Inc. |
Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
|
IL113776A
(en)
|
1994-05-18 |
2008-12-29 |
Bayer Bioscience Gmbh |
Dna sequences coding for enzymes which catalyze the synthesis of linear alpha 1,4 - glucans in plants, fungi and microorganisms
|
WO1995033835A1
(en)
|
1994-06-02 |
1995-12-14 |
Chiron Corporation |
Nucleic acid immunization using a virus-based infection/transfection system
|
GB9412230D0
(en)
|
1994-06-17 |
1994-08-10 |
Celltech Ltd |
Interleukin-5 specific recombiant antibodies
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
US5597696A
(en)
|
1994-07-18 |
1997-01-28 |
Becton Dickinson And Company |
Covalent cyanine dye oligonucleotide conjugates
|
CA2195557C
(en)
|
1994-08-12 |
2006-10-17 |
Shui-On Leung |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
US5597909A
(en)
|
1994-08-25 |
1997-01-28 |
Chiron Corporation |
Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use
|
US5580731A
(en)
|
1994-08-25 |
1996-12-03 |
Chiron Corporation |
N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith
|
US5665545A
(en)
|
1994-11-28 |
1997-09-09 |
Akzo Nobel N.V. |
Terminal repeat amplification method
|
US5641665A
(en)
|
1994-11-28 |
1997-06-24 |
Vical Incorporated |
Plasmids suitable for IL-2 expression
|
US5588960A
(en)
|
1994-12-01 |
1996-12-31 |
Vidamed, Inc. |
Transurethral needle delivery device with cystoscope and method for treatment of urinary incontinence
|
US5807718A
(en)
|
1994-12-02 |
1998-09-15 |
The Scripps Research Institute |
Enzymatic DNA molecules
|
US5585108A
(en)
|
1994-12-30 |
1996-12-17 |
Nanosystems L.L.C. |
Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays
|
ATE373094T1
(en)
|
1995-01-06 |
2007-09-15 |
Plant Res Int Bv |
DNA SEQUENCES CODING FOR CARBOHYDRATE POLYMERS-FORMING ENZYMES AND METHOD FOR PRODUCING TRANSGENIC PLANTS
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US5824497A
(en)
|
1995-02-10 |
1998-10-20 |
Mcmaster University |
High efficiency translation of mRNA molecules
|
EP0727187B1
(en)
|
1995-02-15 |
2003-08-06 |
Joseph Eldor |
Multiple hole spinal needle
|
US5707807A
(en)
|
1995-03-28 |
1998-01-13 |
Research Development Corporation Of Japan |
Molecular indexing for expressed gene analysis
|
US5869230A
(en)
|
1995-03-30 |
1999-02-09 |
Beth Israel Hospital Association |
Gene transfer into the kidney
|
US5986054A
(en)
|
1995-04-28 |
1999-11-16 |
The Hospital For Sick Children, Hsc Research And Development Limited Partnership |
Genetic sequences and proteins related to alzheimer's disease
|
FR2733762B1
(en)
|
1995-05-02 |
1997-08-01 |
Genset Sa |
METHOD FOR THE SPECIFIC COUPLING OF THE HAIR OF THE 5 'END OF A RNAM FRAGMENT AND PREPARATION OF RNAM AND COMPLETE DNA
|
US5700642A
(en)
|
1995-05-22 |
1997-12-23 |
Sri International |
Oligonucleotide sizing using immobilized cleavable primers
|
US6111095A
(en)
|
1995-06-07 |
2000-08-29 |
Merck & Co., Inc. |
Capped synthetic RNA, analogs, and aptamers
|
US6051429A
(en)
|
1995-06-07 |
2000-04-18 |
Life Technologies, Inc. |
Peptide-enhanced cationic lipid transfections
|
US5889136A
(en)
|
1995-06-09 |
1999-03-30 |
The Regents Of The University Of Colorado |
Orthoester protecting groups in RNA synthesis
|
US5766903A
(en)
|
1995-08-23 |
1998-06-16 |
University Technology Corporation |
Circular RNA and uses thereof
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
AU7073096A
(en)
|
1995-09-19 |
1997-04-09 |
University Of Massachusetts |
Inhibited biological degradation of oligodeoxynucleotides
|
US5830879A
(en)
|
1995-10-02 |
1998-11-03 |
St. Elizabeth's Medical Center Of Boston, Inc. |
Treatment of vascular injury using vascular endothelial growth factor
|
US6265387B1
(en)
|
1995-10-11 |
2001-07-24 |
Mirus, Inc. |
Process of delivering naked DNA into a hepatocyte via bile duct
|
EP0771873A3
(en)
|
1995-10-27 |
1998-03-04 |
Takeda Chemical Industries, Ltd. |
Neuronal cell-specific receptor protein
|
CU22584A1
(en)
|
1995-11-17 |
1999-11-03 |
Centro Inmunologia Molecular |
PHARMACEUTICAL COMPOSITIONS CONTAINING A MONOCLONAL ANTIBODY THAT RECOGNIZES THE CD6 HUMAN LEUKOCYTARY DIFFERENTIATION ANTIGEN AND ITS USES FOR THE DIAGNOSIS AND TREATMENT OF PSORIASIS
|
US6090382A
(en)
|
1996-02-09 |
2000-07-18 |
Basf Aktiengesellschaft |
Human antibodies that bind human TNFα
|
US5962271A
(en)
|
1996-01-03 |
1999-10-05 |
Cloutech Laboratories, Inc. |
Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end
|
US6395292B2
(en)
|
1996-02-02 |
2002-05-28 |
Alza Corporation |
Sustained delivery of an active agent using an implantable system
|
US6261584B1
(en)
|
1996-02-02 |
2001-07-17 |
Alza Corporation |
Sustained delivery of an active agent using an implantable system
|
WO1997030064A1
(en)
|
1996-02-16 |
1997-08-21 |
Stichting Rega Vzw |
Hexitol containing oligonucleotides and their use in antisense strategies
|
US6534312B1
(en)
|
1996-02-22 |
2003-03-18 |
Merck & Co., Inc. |
Vaccines comprising synthetic genes
|
US6090391A
(en)
|
1996-02-23 |
2000-07-18 |
Aviron |
Recombinant tryptophan mutants of influenza
|
US6300487B1
(en)
|
1996-03-19 |
2001-10-09 |
Cell Therapuetics, Inc. |
Mammalian lysophosphatidic acid acyltransferase
|
TW517061B
(en)
|
1996-03-29 |
2003-01-11 |
Pharmacia & Amp Upjohn Ab |
Modified/chimeric superantigens and their use
|
US5712127A
(en)
|
1996-04-29 |
1998-01-27 |
Genescape Inc. |
Subtractive amplification
|
US5853719A
(en)
|
1996-04-30 |
1998-12-29 |
Duke University |
Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
|
US7329741B2
(en)
|
1996-06-05 |
2008-02-12 |
Chiron Corporation |
Polynucleotides that hybridize to DP-75 and their use
|
ATE438717T1
(en)
|
1996-06-05 |
2009-08-15 |
Novartis Vaccines & Diagnostic |
DP-75 CODING DNA AND METHOD OF USE THEREOF
|
EP0912607A2
(en)
|
1996-06-21 |
1999-05-06 |
Merck & Co., Inc. |
Vaccines comprising synthetic genes
|
EP0925088A2
(en)
|
1996-06-28 |
1999-06-30 |
Sontra Medical, L.P. |
Ultrasound enhancement of transdermal transport
|
US5939262A
(en)
|
1996-07-03 |
1999-08-17 |
Ambion, Inc. |
Ribonuclease resistant RNA preparation and utilization
|
US5677124A
(en)
|
1996-07-03 |
1997-10-14 |
Ambion, Inc. |
Ribonuclease resistant viral RNA standards
|
US7288266B2
(en)
|
1996-08-19 |
2007-10-30 |
United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Liposome complexes for increased systemic delivery
|
US5849546A
(en)
|
1996-09-13 |
1998-12-15 |
Epicentre Technologies Corporation |
Methods for using mutant RNA polymerases with reduced discrimination between non-canonical and canonical nucleoside triphosphates
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
DK0932678T4
(en)
|
1996-09-24 |
2010-07-12 |
Genentech Inc |
A family of genes encoding apoptosis-related peptides, peptides encoded therein, and methods for their use
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
ATE292980T1
(en)
|
1996-10-11 |
2005-04-15 |
Univ California |
IMMUNO-STIMULATING OLIGONUCLEOTIDE CONJUGATES
|
EP0839912A1
(en)
|
1996-10-30 |
1998-05-06 |
Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) |
Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
|
GB9623051D0
(en)
|
1996-11-06 |
1997-01-08 |
Schacht Etienne H |
Delivery of DNA to target cells in biological systems
|
US5980887A
(en)
|
1996-11-08 |
1999-11-09 |
St. Elizabeth's Medical Center Of Boston |
Methods for enhancing angiogenesis with endothelial progenitor cells
|
US5759179A
(en)
|
1996-12-31 |
1998-06-02 |
Johnson & Johnson Medical, Inc. |
Needle and valve assembly for use with a catheter
|
EP0971946B1
(en)
|
1997-01-21 |
2006-07-05 |
The General Hospital Corporation |
Selection of proteins using rna-protein fusions
|
EP0855184A1
(en)
|
1997-01-23 |
1998-07-29 |
Grayson B. Dr. Lipford |
Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination
|
US6228640B1
(en)
|
1997-02-07 |
2001-05-08 |
Cem Cezayirli |
Programmable antigen presenting cell of CD34 lineage
|
ES2274566T3
(en)
|
1997-02-07 |
2007-05-16 |
MERCK & CO., INC. |
SYNTHETIC GAG GENES OF HIV.
|
US6696291B2
(en)
|
1997-02-07 |
2004-02-24 |
Merck & Co., Inc. |
Synthetic HIV gag genes
|
US6251665B1
(en)
|
1997-02-07 |
2001-06-26 |
Cem Cezayirli |
Directed maturation of stem cells and production of programmable antigen presenting dentritic cells therefrom
|
US6576752B1
(en)
|
1997-02-14 |
2003-06-10 |
Isis Pharmaceuticals, Inc. |
Aminooxy functionalized oligomers
|
JP3756313B2
(en)
|
1997-03-07 |
2006-03-15 |
武 今西 |
Novel bicyclonucleosides and oligonucleotide analogues
|
US6406705B1
(en)
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
US6261281B1
(en)
|
1997-04-03 |
2001-07-17 |
Electrofect As |
Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
|
US5914269A
(en)
|
1997-04-04 |
1999-06-22 |
Isis Pharmaceuticals, Inc. |
Oligonucleotide inhibition of epidermal growth factor receptor expression
|
AU6972798A
(en)
|
1997-04-18 |
1998-11-13 |
University Of Medicine And Dentistry Of New Jersey |
Inhibition of hiv-1 replication by a tat rna-binding domain peptide analog
|
US5958688A
(en)
|
1997-04-28 |
1999-09-28 |
The Trustees Of The University Of Pennsylvania |
Characterization of mRNA patterns in neurites and single cells for medical diagnosis and therapeutics
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
US5989911A
(en)
|
1997-05-09 |
1999-11-23 |
University Of Massachusetts |
Site-specific synthesis of pseudouridine in RNA
|
US6124091A
(en)
|
1997-05-30 |
2000-09-26 |
Research Corporation Technologies, Inc. |
Cell growth-controlling oligonucleotides
|
JP4101888B2
(en)
|
1997-06-06 |
2008-06-18 |
ダイナバックス テクノロジーズ コーポレイション |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
US6589940B1
(en)
|
1997-06-06 |
2003-07-08 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
CA2294988C
(en)
|
1997-07-01 |
2015-11-24 |
Isis Pharmaceuticals Inc. |
Compositions and methods for the delivery of oligonucleotides via the alimentary canal
|
US5994511A
(en)
|
1997-07-02 |
1999-11-30 |
Genentech, Inc. |
Anti-IgE antibodies and methods of improving polypeptides
|
CN1275085A
(en)
|
1997-07-21 |
2000-11-29 |
法玛西雅和厄普约翰公司 |
Cytolysis of target cell, reagent and composition for cytolysis and compound for preparing these reagents
|
US20030073640A1
(en)
|
1997-07-23 |
2003-04-17 |
Ribozyme Pharmaceuticals, Inc. |
Novel compositions for the delivery of negatively charged molecules
|
WO1999006073A1
(en)
|
1997-07-31 |
1999-02-11 |
St. Elizabeth's Medical Center Of Boston, Inc. |
Method for the treatment of grafts
|
US6794499B2
(en)
|
1997-09-12 |
2004-09-21 |
Exiqon A/S |
Oligonucleotide analogues
|
WO1999013896A1
(en)
|
1997-09-18 |
1999-03-25 |
The Trustees Of The University Of Pennsylvania |
Attenuated vif dna immunization cassettes for genetic vaccines
|
AU9319398A
(en)
|
1997-09-19 |
1999-04-05 |
Sequitur, Inc. |
Sense mrna therapy
|
US6004573A
(en)
|
1997-10-03 |
1999-12-21 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
AU750106B2
(en)
|
1997-10-07 |
2002-07-11 |
University Of Maryland Biotechnology Institute |
Method for introducing and expressing RNA in animal cells
|
US6593463B1
(en)
|
1997-10-20 |
2003-07-15 |
Genzyme Transgenics Corporation |
Modified MSP-1 nucleic acid sequences and methods for increasing MRNA levels and protein expression in cell systems
|
US6019747A
(en)
|
1997-10-21 |
2000-02-01 |
I-Flow Corporation |
Spring-actuated infusion syringe
|
AU1275899A
(en)
|
1997-10-24 |
1999-05-17 |
Megabios Corporation |
Methods for preparing polynucleotide transfection complexes
|
US6548633B1
(en)
|
1998-12-22 |
2003-04-15 |
Genset, S.A. |
Complementary DNA's encoding proteins with signal peptides
|
CA2641217A1
(en)
|
1997-11-20 |
1999-06-03 |
Vical Incorporated |
Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor
|
US7655777B2
(en)
|
1997-11-24 |
2010-02-02 |
Monsanto Technology Llc |
Nucleic acid molecules associated with the tocopherol pathway
|
US6517869B1
(en)
|
1997-12-12 |
2003-02-11 |
Expression Genetics, Inc. |
Positively charged poly(alpha-(omega-aminoalkyl)lycolic acid) for the delivery of a bioactive agent via tissue and cellular uptake
|
ZA9811377B
(en)
|
1997-12-12 |
1999-08-27 |
Expression Genetics Inc |
Positively charged poly[alpha-(omega-aminoalkyl) glycolic acid[ for the delivery of a bioactive agent via tissue and cellular uptake.
|
US6320017B1
(en)
|
1997-12-23 |
2001-11-20 |
Inex Pharmaceuticals Corp. |
Polyamide oligomers
|
JP2002500010A
(en)
|
1997-12-23 |
2002-01-08 |
カイロン コーポレイション |
Human genes and gene expression products I
|
US6383811B2
(en)
|
1997-12-30 |
2002-05-07 |
Mirus Corporation |
Polyampholytes for delivering polyions to a cell
|
EP2138191A1
(en)
|
1998-01-05 |
2009-12-30 |
University Of Washington |
Enhanced transport using membrane disruptive agents
|
CA2317777C
(en)
|
1998-01-08 |
2005-05-03 |
Sontra Medical, Inc. |
Sonophoretic enhanced transdermal transport
|
US8287483B2
(en)
|
1998-01-08 |
2012-10-16 |
Echo Therapeutics, Inc. |
Method and apparatus for enhancement of transdermal transport
|
US6426086B1
(en)
|
1998-02-03 |
2002-07-30 |
The Regents Of The University Of California |
pH-sensitive, serum-stable liposomes
|
US6365346B1
(en)
|
1998-02-18 |
2002-04-02 |
Dade Behring Inc. |
Quantitative determination of nucleic acid amplification products
|
US5955310A
(en)
|
1998-02-26 |
1999-09-21 |
Novo Nordisk Biotech, Inc. |
Methods for producing a polypeptide in a bacillus cell
|
US6432925B1
(en)
|
1998-04-16 |
2002-08-13 |
John Wayne Cancer Institute |
RNA cancer vaccine and methods for its use
|
US6429301B1
(en)
|
1998-04-17 |
2002-08-06 |
Whitehead Institute For Biomedical Research |
Use of a ribozyme to join nucleic acids and peptides
|
GB9808327D0
(en)
|
1998-04-20 |
1998-06-17 |
Chiron Spa |
Antidiotypic compounds
|
EP2116600B1
(en)
|
1998-04-23 |
2013-09-18 |
Takara Bio Inc. |
Method for synthesizing DNA
|
US6395253B2
(en)
|
1998-04-23 |
2002-05-28 |
The Regents Of The University Of Michigan |
Microspheres containing condensed polyanionic bioactive agents and methods for their production
|
US20020064517A1
(en)
|
1998-04-30 |
2002-05-30 |
Stewart A. Cederholm-Williams |
Fibrin sealant as a transfection/transformation vehicle for gene therapy
|
US20090208418A1
(en)
|
2005-04-29 |
2009-08-20 |
Innexus Biotechnology Internaltional Ltd. |
Superantibody synthesis and use in detection, prevention and treatment of disease
|
CA2329147A1
(en)
|
1998-05-20 |
1999-11-25 |
Feng Liu |
A hepatocyte targeting polyethylene glyco-grafted poly-l-lysine polymeric gene carrier
|
US6503231B1
(en)
|
1998-06-10 |
2003-01-07 |
Georgia Tech Research Corporation |
Microneedle device for transport of molecules across tissue
|
US7091192B1
(en)
|
1998-07-01 |
2006-08-15 |
California Institute Of Technology |
Linear cyclodextrin copolymers
|
BR9912070A
(en)
|
1998-07-13 |
2001-04-10 |
Expression Genetics Inc |
Poly-l-lysine polyester analog as a soluble, biodegradable gene delivery vehicle
|
US6222030B1
(en)
|
1998-08-03 |
2001-04-24 |
Agilent Technologies, Inc. |
Solid phase synthesis of oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection
|
CN1689646A
(en)
|
1998-08-11 |
2005-11-02 |
拜奥根Idec公司 |
Combination therapies for B-cell lynphomas comprising administration of anti-CD20 antibody
|
GB9817662D0
(en)
|
1998-08-13 |
1998-10-07 |
Crocker Peter J |
Substance delivery
|
US6924365B1
(en)
|
1998-09-29 |
2005-08-02 |
Transkaryotic Therapies, Inc. |
Optimized messenger RNA
|
US20090042283A1
(en)
|
1998-09-29 |
2009-02-12 |
Shire Human Genetic Therapies, Inc., A Delaware Corporation |
Optimized messenger rna
|
WO2000026226A1
(en)
|
1998-11-03 |
2000-05-11 |
Yale University |
Multidomain polynucleotide molecular sensors
|
DK2055313T3
(en)
|
1998-11-09 |
2015-07-27 |
Biogen Inc |
Treatment of Hematologic Malignancies Related to Circulating Tumor Cells Using Chimeric Anti-CD20 Antibody
|
CA2350064C
(en)
|
1998-11-09 |
2012-05-08 |
Idec Pharmaceuticals Corporation |
Chimeric anti-cd20 antibody treatment of patients receiving bmt or pbsc transplants
|
WO2000027340A2
(en)
|
1998-11-12 |
2000-05-18 |
The Children's Medical Center Corporation |
USE OF t-RNA AND FRAGMENTS FOR INHIBITING ANGIOGENESIS AND COMPOSITIONS THEREOF
|
US6210931B1
(en)
|
1998-11-30 |
2001-04-03 |
The United States Of America As Represented By The Secretary Of Agriculture |
Ribozyme-mediated synthesis of circular RNA
|
US20040171980A1
(en)
|
1998-12-18 |
2004-09-02 |
Sontra Medical, Inc. |
Method and apparatus for enhancement of transdermal transport
|
AU3128000A
(en)
|
1998-12-23 |
2000-07-31 |
Human Genome Sciences, Inc. |
Peptidoglycan recognition proteins
|
EP1155124A2
(en)
|
1999-02-22 |
2001-11-21 |
European Molecular Biology Laboratory |
In vitro translation system
|
US6255476B1
(en)
|
1999-02-22 |
2001-07-03 |
Pe Corporation (Ny) |
Methods and compositions for synthesis of labelled oligonucleotides and analogs on solid-supports
|
US7629311B2
(en)
|
1999-02-24 |
2009-12-08 |
Edward Lewis Tobinick |
Methods to facilitate transmission of large molecules across the blood-brain, blood-eye, and blood-nerve barriers
|
EP1574210B1
(en)
|
1999-02-26 |
2016-04-06 |
Novartis Vaccines and Diagnostics, Inc. |
Microemulsions with adsorbed macromolecules
|
US7084125B2
(en)
|
1999-03-18 |
2006-08-01 |
Exiqon A/S |
Xylo-LNA analogues
|
EP1165798A2
(en)
|
1999-03-29 |
2002-01-02 |
Statens Serum Institut |
Nucleotide construct with optimised codons for an hiv genetic vaccine based on a primary, early hiv isolate and synthetic envelope
|
CN1311005C
(en)
|
1999-04-09 |
2007-04-18 |
迪纳尔生物技术公司 |
Process for the preparation of monodisperse polymer particles
|
PT1178999E
(en)
|
1999-05-04 |
2007-06-26 |
Santaris Pharma As |
L-ribo-lna analogues
|
KR20020011985A
(en)
|
1999-05-07 |
2002-02-09 |
파르마솔 게엠베하 |
Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
|
EP1637160A3
(en)
|
1999-05-07 |
2006-05-03 |
Genentech, Inc. |
Treatment of autoimmune diseases with antagonists which bind to B cell surface markers
|
US7074403B1
(en)
|
1999-06-09 |
2006-07-11 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target B-cells
|
US6346382B1
(en)
|
1999-06-01 |
2002-02-12 |
Vanderbilt University |
Human carbamyl phosphate synthetase I polymorphism and diagnostic methods related thereto
|
AU4332399A
(en)
|
1999-06-04 |
2000-12-28 |
Cheng-Ming Chuong |
Rna polymerase chain reaction
|
US6611707B1
(en)
|
1999-06-04 |
2003-08-26 |
Georgia Tech Research Corporation |
Microneedle drug delivery device
|
US6743211B1
(en)
|
1999-11-23 |
2004-06-01 |
Georgia Tech Research Corporation |
Devices and methods for enhanced microneedle penetration of biological barriers
|
US7098032B2
(en)
|
2001-01-02 |
2006-08-29 |
Mirus Bio Corporation |
Compositions and methods for drug delivery using pH sensitive molecules
|
DK1102785T3
(en)
|
1999-06-07 |
2013-05-13 |
Arrowhead Res Corp |
Compositions for drug delivery using pH-sensitive molecules
|
US6303573B1
(en)
|
1999-06-07 |
2001-10-16 |
The Burnham Institute |
Heart homing peptides and methods of using same
|
CA2376634A1
(en)
|
1999-06-08 |
2000-12-14 |
Aventis Pasteur |
Immunostimulant oligonucleotide
|
AU5799200A
(en)
|
1999-06-24 |
2001-01-31 |
Academic Hospital At The University Of Amsterdam |
Lpl variant therapeutics
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
IL147179A0
(en)
|
1999-06-30 |
2002-08-14 |
Advanced Cell Tech Inc |
Cytoplasmic transfer to de-differentiate recipient cells
|
US6514948B1
(en)
|
1999-07-02 |
2003-02-04 |
The Regents Of The University Of California |
Method for enhancing an immune response
|
JP2003504061A
(en)
|
1999-07-09 |
2003-02-04 |
ワイス |
Methods and compositions for preventing formation of aberrant RNA during transcription of plasmid sequences
|
CA2311201A1
(en)
|
1999-08-05 |
2001-02-05 |
Genset S.A. |
Ests and encoded human proteins
|
US8557244B1
(en)
|
1999-08-11 |
2013-10-15 |
Biogen Idec Inc. |
Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
|
MXPA02001911A
(en)
|
1999-08-24 |
2003-07-21 |
Medarex Inc |
Human ctla 4 antibodies and their uses.
|
US20050112141A1
(en)
|
2000-08-30 |
2005-05-26 |
Terman David S. |
Compositions and methods for treatment of neoplastic disease
|
US20040106567A1
(en)
|
1999-09-07 |
2004-06-03 |
Hagstrom James E. |
Intravascular delivery of non-viral nucleic acid
|
ATE289630T1
(en)
|
1999-09-09 |
2005-03-15 |
Curevac Gmbh |
TRANSFER OF MRNAS USING POLYCATIONIC COMPOUNDS
|
AU7398200A
(en)
|
1999-09-17 |
2001-04-24 |
Aventis Pasteur Limited |
Chlamydia antigens and corresponding dna fragments and uses thereof
|
US6623457B1
(en)
|
1999-09-22 |
2003-09-23 |
Becton, Dickinson And Company |
Method and apparatus for the transdermal administration of a substance
|
WO2002064799A2
(en)
|
1999-09-28 |
2002-08-22 |
Transkaryotic Therapies, Inc. |
Optimized messenger rna
|
AU7725500A
(en)
|
1999-09-30 |
2001-04-30 |
National Jewish Medical And Research Center |
Method for inhibition of pathogenic microorganisms
|
WO2001025488A2
(en)
|
1999-10-06 |
2001-04-12 |
Quark Biotech, Inc. |
Method for enrichment of natural antisense messenger rna
|
US7060291B1
(en)
|
1999-11-24 |
2006-06-13 |
Transave, Inc. |
Modular targeted liposomal delivery system
|
US6613026B1
(en)
|
1999-12-08 |
2003-09-02 |
Scimed Life Systems, Inc. |
Lateral needle-less injection apparatus and method
|
US6277974B1
(en)
|
1999-12-14 |
2001-08-21 |
Cogent Neuroscience, Inc. |
Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death
|
US6245929B1
(en)
|
1999-12-20 |
2001-06-12 |
General Electric Company |
Catalyst composition and method for producing diaryl carbonates, using bisphosphines
|
KR20010102300A
(en)
|
1999-12-22 |
2001-11-15 |
간디 지오프레이 에이치. |
Alpha-olefin polymerization catalyst system which contains an aromatic silane compound
|
US7737108B1
(en)
|
2000-01-07 |
2010-06-15 |
University Of Washington |
Enhanced transport using membrane disruptive agents
|
AU2001232485A1
(en)
|
2000-01-13 |
2001-07-24 |
Amsterdam Support Diagnostics B.V. |
A universal nucleic acid amplification system for nucleic acids in a sample
|
AU2001231245A1
(en)
|
2000-01-31 |
2001-08-07 |
The Regents Of The University Of California |
Immunomodulatory polynucleotides in treatment of an infection by an intracellular pathogen
|
CA2395811A1
(en)
|
2000-01-31 |
2001-08-02 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
US7491805B2
(en)
|
2001-05-18 |
2009-02-17 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
US7833992B2
(en)
|
2001-05-18 |
2010-11-16 |
Merck Sharpe & Dohme |
Conjugates and compositions for cellular delivery
|
US6602498B2
(en)
|
2000-02-22 |
2003-08-05 |
Shearwater Corporation |
N-maleimidyl polymer derivatives
|
BRPI0108676B8
(en)
|
2000-02-24 |
2021-05-25 |
Lilly Co Eli |
humanized antibodies that sequester amyloid beta peptide and their uses in the treatment of conditions characterized by formation of amyloid plaques, as well as a pharmaceutical composition comprising said antibodies
|
WO2001066149A2
(en)
|
2000-03-03 |
2001-09-13 |
Valentis, Inc. |
Nucleic acid formulations for gene delivery and methods of use
|
AU2001249727A1
(en)
|
2000-03-31 |
2001-10-15 |
Genentech, Inc. |
Compositions and methods for detecting and quantifying gene expression
|
JP2004500412A
(en)
|
2000-03-31 |
2004-01-08 |
アイデック ファーマスーティカルズ コーポレイション |
Combination of anti-cytokine antibody or antagonist and anti-CD20 for treatment of B-cell lymphoma
|
US6565572B2
(en)
|
2000-04-10 |
2003-05-20 |
Sdgi Holdings, Inc. |
Fenestrated surgical screw and method
|
EP2267026A1
(en)
|
2000-04-12 |
2010-12-29 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
US6368801B1
(en)
|
2000-04-12 |
2002-04-09 |
Molecular Staging, Inc. |
Detection and amplification of RNA using target-mediated ligation of DNA by RNA ligase
|
US20010046496A1
(en)
|
2000-04-14 |
2001-11-29 |
Brettman Lee R. |
Method of administering an antibody
|
US6375972B1
(en)
|
2000-04-26 |
2002-04-23 |
Control Delivery Systems, Inc. |
Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
|
US20040229271A1
(en)
|
2000-05-19 |
2004-11-18 |
Williams Richard B. |
Compositions and methods for the identification and selection of nucleic acids and polypeptides
|
WO2001092523A2
(en)
|
2000-05-30 |
2001-12-06 |
Curagen Corporation |
Human polynucleotides and polypeptides encoded thereby
|
JP2004530629A
(en)
|
2000-06-07 |
2004-10-07 |
バイオシネクサス インコーポレーテッド |
Immunostimulatory RNA / DNA hybrid molecule
|
US6664066B2
(en)
|
2000-06-23 |
2003-12-16 |
Wyeth Holdings Corporation |
Modified Morbillivirus V proteins
|
EP1297005B1
(en)
|
2000-07-03 |
2009-08-26 |
Novartis Vaccines and Diagnostics S.r.l. |
Immunisation against chlamydia pneumoniae
|
US6440096B1
(en)
|
2000-07-14 |
2002-08-27 |
Becton, Dickinson And Co. |
Microdevice and method of manufacturing a microdevice
|
EP1304374A4
(en)
|
2000-07-18 |
2004-09-29 |
Bml Inc |
Method of detecting lipid metabolic errors
|
WO2002008435A1
(en)
|
2000-07-21 |
2002-01-31 |
Glaxo Group Limited |
Codon-optimized papilloma virus sequences
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
US20040142474A1
(en)
|
2000-09-14 |
2004-07-22 |
Expression Genetics, Inc. |
Novel cationic lipopolymer as a biocompatible gene delivery agent
|
US6696038B1
(en)
|
2000-09-14 |
2004-02-24 |
Expression Genetics, Inc. |
Cationic lipopolymer as biocompatible gene delivery agent
|
AU2001290078A1
(en)
|
2000-09-20 |
2002-04-02 |
Ruggero Della Bitta |
Stem cell therapy
|
JP2004510714A
(en)
|
2000-10-04 |
2004-04-08 |
ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア |
Compositions and methods using capsid proteins from flaviviruses and pestiviruses
|
WO2002028875A2
(en)
|
2000-10-04 |
2002-04-11 |
Cureon A/S |
Improved synthesis of purine locked nucleic acid analogues
|
US6998115B2
(en)
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
US6649138B2
(en)
|
2000-10-13 |
2003-11-18 |
Quantum Dot Corporation |
Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media
|
US7202226B2
(en)
|
2000-10-23 |
2007-04-10 |
Detroit R & D |
Augmentation of wound healing by elF-4E mRNA and EGF mRNA
|
US20030077604A1
(en)
|
2000-10-27 |
2003-04-24 |
Yongming Sun |
Compositions and methods relating to breast specific genes and proteins
|
US20020132788A1
(en)
|
2000-11-06 |
2002-09-19 |
David Lewis |
Inhibition of gene expression by delivery of small interfering RNA to post-embryonic animal cells in vivo
|
AU2002226930A1
(en)
|
2000-11-17 |
2002-05-27 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Reduction of the nonspecific animal toxicity of immunotoxins by mutating the framework regions of the fv to lower the isoelectric point
|
CA2430379A1
(en)
|
2000-12-07 |
2002-06-13 |
Chiron Corporation |
Endogenous retroviruses up-regulated in prostate cancer
|
US7708915B2
(en)
|
2004-05-06 |
2010-05-04 |
Castor Trevor P |
Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein
|
US20020130430A1
(en)
|
2000-12-29 |
2002-09-19 |
Castor Trevor Percival |
Methods for making polymer microspheres/nanospheres and encapsulating therapeutic proteins and other products
|
EP1224943A1
(en)
|
2001-01-19 |
2002-07-24 |
Crucell Holland B.V. |
Fibronectin as a tumor marker detected by phage antibodies
|
NZ527221A
(en)
|
2001-01-19 |
2006-09-29 |
Vironovative B |
A negative-sense single stranded RNA virus causing respiratory tract illness in susceptible mammals
|
US20040110191A1
(en)
|
2001-01-31 |
2004-06-10 |
Winkler Matthew M. |
Comparative analysis of nucleic acids using population tagging
|
US6897196B1
(en)
|
2001-02-07 |
2005-05-24 |
The Regents Of The University Of California |
pH sensitive lipids based on ortho ester linkers, composition and method
|
WO2002065093A2
(en)
|
2001-02-14 |
2002-08-22 |
Baylor College Of Medicine |
Methods and compositions of amplifying rna
|
US6652886B2
(en)
|
2001-02-16 |
2003-11-25 |
Expression Genetics |
Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
|
DE10109897A1
(en)
|
2001-02-21 |
2002-11-07 |
Novosom Ag |
Optional cationic liposomes and their use
|
US7232425B2
(en)
|
2001-03-02 |
2007-06-19 |
Sorenson Development, Inc. |
Apparatus and method for specific interstitial or subcutaneous diffusion and dispersion of medication
|
JP2004530425A
(en)
|
2001-03-09 |
2004-10-07 |
ジーン ストリーム プロプライエトリー リミティッド |
Novel expression vector
|
JP2002262882A
(en)
|
2001-03-12 |
2002-09-17 |
Nisshinbo Ind Inc |
Method for amplifying rna
|
FR2822164B1
(en)
|
2001-03-19 |
2004-06-18 |
Centre Nat Rech Scient |
POLYPEPTIDES DERIVED FROM POLYMERASE RNAS, AND USES THEREOF
|
US6520949B2
(en)
|
2001-04-02 |
2003-02-18 |
Martin St. Germain |
Method and apparatus for administering fluid to animals subcutaneously
|
DE10119005A1
(en)
|
2001-04-18 |
2002-10-24 |
Roche Diagnostics Gmbh |
Process for protein expression starting from stabilized linear short DNA in cell-free in vitro transcription / translation systems with exonuclease-containing lysates or in a cellular system containing exonucleases
|
US20030171253A1
(en)
|
2001-04-19 |
2003-09-11 |
Averil Ma |
Methods and compositions relating to modulation of A20
|
DE50201240D1
(en)
|
2001-04-23 |
2004-11-11 |
Amaxa Gmbh |
BUFFER SOLUTION FOR ELECTROPORATION AND METHOD COMPREHENSIVE USE
|
US7560424B2
(en)
|
2001-04-30 |
2009-07-14 |
Zystor Therapeutics, Inc. |
Targeted therapeutic proteins
|
US6777187B2
(en)
|
2001-05-02 |
2004-08-17 |
Rubicon Genomics, Inc. |
Genome walking by selective amplification of nick-translate DNA library and amplification from complex mixtures of templates
|
EP1392587A4
(en)
|
2001-05-08 |
2009-03-18 |
Magnatech International L P |
Electronic length control wire pay-off system and method
|
US20050137155A1
(en)
|
2001-05-18 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of Parkinson disease using short interfering nucleic acid (siNA)
|
US8137911B2
(en)
|
2001-05-22 |
2012-03-20 |
Cellscript, Inc. |
Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
|
CA2449054C
(en)
|
2001-05-30 |
2011-01-04 |
The Scripps Research Institute |
Integrin targeting liposome for nucleic acid delivery
|
EP1604688B1
(en)
|
2001-06-05 |
2010-02-03 |
CureVac GmbH |
Stabilised tumour-antigen mRNA with increased G/C-content
|
US20040175787A1
(en)
|
2001-06-18 |
2004-09-09 |
Klemens Kaupmann |
Novel g-protein coupled receptors and dna sequences thereof
|
US7785610B2
(en)
|
2001-06-21 |
2010-08-31 |
Dynavax Technologies Corporation |
Chimeric immunomodulatory compounds and methods of using the same—III
|
US7547551B2
(en)
|
2001-06-21 |
2009-06-16 |
University Of Antwerp. |
Transfection of eukaryontic cells with linear polynucleotides by electroporation
|
JP2005503137A
(en)
|
2001-06-26 |
2005-02-03 |
ノバルティス アクチエンゲゼルシャフト |
G protein coupled receptor and DNA sequence thereof
|
SE0102327D0
(en)
|
2001-06-28 |
2001-06-28 |
Active Biotech Ab |
A novel engineered superantigen for human therapy
|
US20040236092A1
(en)
|
2001-07-13 |
2004-11-25 |
Roman Dziarski |
Peptidologlycan recognition protein encoding nucleic acids and methods of use thereof
|
US6586524B2
(en)
|
2001-07-19 |
2003-07-01 |
Expression Genetics, Inc. |
Cellular targeting poly(ethylene glycol)-grafted polymeric gene carrier
|
AU2002319668A1
(en)
|
2001-07-27 |
2003-02-17 |
President And Fellows Of Harvard College |
Laminar mixing apparatus and methods
|
WO2003012030A2
(en)
|
2001-08-01 |
2003-02-13 |
University Of Utah, Technology Transfer Office |
Isoform-selective inhibitors and activators of pde3 cyclic
|
JP2005502344A
(en)
|
2001-08-27 |
2005-01-27 |
ノバルティス アクチエンゲゼルシャフト |
Novel G protein coupled receptor and DNA sequence thereof
|
US20040142325A1
(en)
|
2001-09-14 |
2004-07-22 |
Liat Mintz |
Methods and systems for annotating biomolecular sequences
|
EP2385123B1
(en)
|
2001-09-28 |
2018-04-25 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Microrna molecules
|
AR045702A1
(en)
|
2001-10-03 |
2005-11-09 |
Chiron Corp |
COMPOSITIONS OF ASSISTANTS.
|
WO2003028657A2
(en)
|
2001-10-03 |
2003-04-10 |
The Johns Hopkins University |
Compositions for oral gene therapy and methods of using same
|
DE10148886A1
(en)
|
2001-10-04 |
2003-04-30 |
Avontec Gmbh |
Inhibition of STAT-1
|
US7276489B2
(en)
|
2002-10-24 |
2007-10-02 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends
|
DE60231901D1
(en)
|
2001-11-14 |
2009-05-20 |
Toyo Boseki |
DNA SYNTHESIS ENGINES, FACTORS ASSOCIATED WITH DNA POLYMERASE, AND USE THEREOF
|
AU2002361642A1
(en)
|
2001-11-16 |
2003-06-10 |
The University Of Tennessee Research Corporation |
Recombinant antibody fusion proteins and methods for detection of apoptotic cells
|
US20050032062A1
(en)
|
2001-11-29 |
2005-02-10 |
Salah-Dine Chibout |
Methods for the assessment and prognosis of sarcoidosis
|
CA2409775C
(en)
|
2001-12-03 |
2010-07-13 |
F. Hoffmann-La Roche Ag |
Reversibly modified thermostable enzymes for dna synthesis and amplification in vitro
|
US20060275747A1
(en)
|
2001-12-07 |
2006-12-07 |
Hardy Stephen F |
Endogenous retrovirus up-regulated in prostate cancer
|
US20070037147A1
(en)
|
2001-12-07 |
2007-02-15 |
Pablo Garcia |
Endogenous retrovirus polypeptides linked to oncogenic transformation
|
JP4646315B2
(en)
|
2001-12-07 |
2011-03-09 |
ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド |
Endogenous retroviruses up-regulated in prostate cancer
|
EP1458755A2
(en)
|
2001-12-17 |
2004-09-22 |
Novartis AG |
Novel g-protein coupled receptors and dna sequences thereof
|
DE10162480A1
(en)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
The application of mRNA for use as a therapeutic agent against tumor diseases
|
CA2467763C
(en)
|
2001-12-21 |
2011-09-13 |
Alcon, Inc. |
Use of synthetic inorganic nanoparticles as carriers for ophthalmic and otic drugs
|
AU2003235707A1
(en)
|
2002-01-18 |
2003-07-30 |
Curevac Gmbh |
Immunogenic preparations and vaccines on the basis of mrna
|
EP1474432A1
(en)
|
2002-02-04 |
2004-11-10 |
Biomira Inc. |
Immunostimulatory, covalently lipidated oligonucleotides
|
ATE417858T1
(en)
|
2002-02-05 |
2009-01-15 |
Genentech Inc |
PROTEIN PURIFICATION
|
FR2835749B1
(en)
|
2002-02-08 |
2006-04-14 |
Inst Nat Sante Rech Med |
PHARMACEUTICAL COMPOSITION IMPROVING IN VIVO GENE TRANSFER
|
DE10207178A1
(en)
|
2002-02-19 |
2003-09-04 |
Novosom Ag |
Components for the production of amphoteric liposomes
|
AR038568A1
(en)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
ANTI-A BETA ANTIBODIES AND ITS USE
|
US20050222064A1
(en)
|
2002-02-20 |
2005-10-06 |
Sirna Therapeutics, Inc. |
Polycationic compositions for cellular delivery of polynucleotides
|
US7354742B2
(en)
|
2002-02-22 |
2008-04-08 |
Ortho-Mcneil Pharmaceutical, Inc. |
Method for generating amplified RNA
|
US7476390B2
(en)
|
2002-02-26 |
2009-01-13 |
Maxygen, Inc. |
Flavivirus antigens
|
AU2003213687A1
(en)
|
2002-03-04 |
2003-09-22 |
Imclone Systems Incorporated |
Human antibodies specific to kdr and uses thereof
|
AU2003221497A1
(en)
|
2002-03-13 |
2003-09-22 |
Novartis Ag |
Pharmaceutical microparticles
|
US7074596B2
(en)
|
2002-03-25 |
2006-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Synthesis and use of anti-reverse mRNA cap analogues
|
CA2480775C
(en)
|
2002-04-04 |
2016-05-31 |
Coley Pharmaceutical Gmbh |
Immunostimulatory g,u-containing oligoribonucleotides
|
AU2003226820A1
(en)
|
2002-04-17 |
2003-10-27 |
Novartis Ag |
Method for the identification of inhibitors of the binding of are-containing mrn a and an hur protein
|
GB0209539D0
(en)
|
2002-04-26 |
2002-06-05 |
Avecia Ltd |
Monomer Polymer and process
|
EP1361277A1
(en)
|
2002-04-30 |
2003-11-12 |
Centre National De La Recherche Scientifique (Cnrs) |
Optimization of transgene expression in mammalian cells
|
BR122019027966B8
(en)
|
2002-05-02 |
2021-07-27 |
Wyeth Corp |
monomeric calicheamicin derivative/anti-cd22 antibody conjugate and their use
|
US20040018525A1
(en)
|
2002-05-21 |
2004-01-29 |
Bayer Aktiengesellschaft |
Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasma
|
US7374930B2
(en)
|
2002-05-21 |
2008-05-20 |
Expression Genetics, Inc. |
GLP-1 gene delivery for the treatment of type 2 diabetes
|
DE10224200C1
(en)
|
2002-05-31 |
2003-08-21 |
Artus Ges Fuer Molekularbiolog |
Replicating RNA, useful, after reverse transcription, for analysis on microarrays, comprises conversion to cDNA then reverse transcription of this to form antisense sequences
|
WO2003101401A2
(en)
|
2002-06-03 |
2003-12-11 |
Chiron Corporation |
Use of nrg4, or inhibitors thereof, in the treatment of colon and pancreatic cancer
|
US20040001810A1
(en)
|
2002-06-26 |
2004-01-01 |
Davis Roger A. |
Compositions and methods for treating atherosclerosis
|
WO2004002453A1
(en)
|
2002-06-28 |
2004-01-08 |
Protiva Biotherapeutics Ltd. |
Method and apparatus for producing liposomes
|
AU2003251770B9
(en)
|
2002-07-01 |
2009-06-04 |
H. Lundbeck A/S |
Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
|
DE10229872A1
(en)
|
2002-07-03 |
2004-01-29 |
Curevac Gmbh |
Immune stimulation through chemically modified RNA
|
GB0215509D0
(en)
|
2002-07-04 |
2002-08-14 |
Novartis Ag |
Marker genes
|
ATE505476T1
(en)
|
2002-07-16 |
2011-04-15 |
VGX Pharmaceuticals LLC |
CODON-OPTIMIZED SYNTHETIC PLASMIDS
|
EP1543157A4
(en)
|
2002-07-24 |
2006-11-15 |
Ptc Therapeutics Inc |
METHODS FOR IDENTIFYING SMALL MOLEDULES THAT MODULATE PREMATURE TRANSLATION TERMINATION AND NONSENSE MEDIATED mRNA DECAY
|
EP1393745A1
(en)
|
2002-07-29 |
2004-03-03 |
Hybridon, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5'ends
|
EP1386925A1
(en)
|
2002-07-31 |
2004-02-04 |
Girindus AG |
Method for preparing oligonucleotides
|
US6653468B1
(en)
|
2002-07-31 |
2003-11-25 |
Isis Pharmaceuticals, Inc. |
Universal support media for synthesis of oligomeric compounds
|
EP1873180B1
(en)
|
2002-08-14 |
2014-05-07 |
Novartis AG |
Ophthalmic device made from a radiation-curable prepolymer
|
EP2277551B1
(en)
|
2002-09-06 |
2013-05-08 |
Cerulean Pharma Inc. |
Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto
|
US7569214B2
(en)
|
2002-09-09 |
2009-08-04 |
Nektar Therapeutics Al, Corporation |
Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid
|
US7534872B2
(en)
|
2002-09-27 |
2009-05-19 |
Syngen, Inc. |
Compositions and methods for the use of FMOC derivatives in DNA/RNA synthesis
|
WO2004035607A2
(en)
|
2002-10-17 |
2004-04-29 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
AU2003301576A1
(en)
|
2002-10-22 |
2004-05-13 |
Eisai Co., Ltd. |
Gene expressed specifically in dopamine-producing neuron precursor cells after termination of division
|
US7265096B2
(en)
|
2002-11-04 |
2007-09-04 |
Xenoport, Inc. |
Gemcitabine prodrugs, pharmaceutical compositions and uses thereof
|
EP1585824A4
(en)
|
2002-11-21 |
2008-01-02 |
Epict Technologies |
Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
|
US7491234B2
(en)
|
2002-12-03 |
2009-02-17 |
Boston Scientific Scimed, Inc. |
Medical devices for delivery of therapeutic agents
|
BRPI0316779B1
(en)
|
2002-12-16 |
2020-04-28 |
Genentech Inc |
humanized antibody that binds human cd20, composition, manufactured article, apoptosis induction method, cd20 positive cancer treatment method, autoimmune disease treatment methods, isolated nucleic acids, expression vectors, host cells, method for producing a humanized 2h7 antibody, isolated polypeptide, liquid formulation, method of treating rheumatoid arthritis (ra) and humanized cd20 binding antibodies
|
US7625872B2
(en)
|
2002-12-23 |
2009-12-01 |
Dynavax Technologies Corporation |
Branched immunomodulatory compounds and methods of using the same
|
US7169892B2
(en)
|
2003-01-10 |
2007-01-30 |
Astellas Pharma Inc. |
Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems
|
US20080227085A1
(en)
|
2003-01-17 |
2008-09-18 |
Pellegrini Matthew C |
Methods and Systems for the Identification of Rna Regulatory Sequences and Compounds that Modulate their Function
|
US9068234B2
(en)
|
2003-01-21 |
2015-06-30 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating gene expression
|
US8426194B2
(en)
|
2003-01-21 |
2013-04-23 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating VEGF expression
|
EP2500437B1
(en)
|
2003-01-21 |
2016-11-30 |
PTC Therapeutics, Inc. |
Methods for identifying compounds that modulate untranslated region-dependent gene expression and methods of using same
|
CN1780910A
(en)
*
|
2003-01-28 |
2006-05-31 |
拉塞有限公司 |
Method and device for the detection of mutations in isolated gene sequences of the low-density lipoprotein receptor (LDL-R) which is associated with familial hypercholesterolemia
|
US20040147027A1
(en)
|
2003-01-28 |
2004-07-29 |
Troy Carol M. |
Complex for facilitating delivery of dsRNA into a cell and uses thereof
|
AU2004207187B2
(en)
|
2003-01-28 |
2009-01-08 |
Progenika Biopharma, S.A. |
Method and device for the detection of mutations in isolated gene sequences of the low-density lipoprotein receptor (LDL-r) which is associated with familial hypercholesterolemia
|
MY162623A
(en)
|
2003-02-10 |
2017-06-30 |
Biogen Ma Inc |
Immunoglobulin formulation and method of preparation thereof
|
US20040167090A1
(en)
|
2003-02-21 |
2004-08-26 |
Monahan Sean D. |
Covalent modification of RNA for in vitro and in vivo delivery
|
WO2004076645A2
(en)
|
2003-02-27 |
2004-09-10 |
University Of Massachusetts |
Compositions and methods for cytomegalovirus treatment
|
CA2450289A1
(en)
|
2003-03-20 |
2005-05-19 |
Imclone Systems Incorporated |
Method of producing an antibody to epidermal growth factor receptor
|
US7320961B2
(en)
|
2003-03-24 |
2008-01-22 |
Abbott Laboratories |
Method for treating a disease, disorder or adverse effect caused by an elevated serum concentration of an UGT1A1 substrate
|
AU2004225520A1
(en)
|
2003-03-25 |
2004-10-14 |
Stratagene |
DNA polymerase fusions and uses thereof
|
WO2004092329A2
(en)
|
2003-04-08 |
2004-10-28 |
Galenica Pharmaceuticals, Inc. |
Semi-synthetic saponin analogs with carrier and immune stimulatory activities for dna and rna vaccines
|
ES2322267T3
(en)
|
2003-04-09 |
2009-06-18 |
Genentech, Inc. |
THERAPY OF AN AUTOINMUNOLOGICAL DISEASE IN A PATIENT THAT PRESENTS AN INAPPROPRIATE RESPONSE TO A TNF-ALFA INHIBITOR.
|
EP2314327B2
(en)
|
2003-05-05 |
2017-09-20 |
Ben-Gurion University Of The Negev Research And Development Authority |
Injectable cross-linked polymeric preparations and uses thereof
|
DE602004031390D1
(en)
|
2003-05-06 |
2011-03-24 |
Syntonix Pharmaceuticals Inc |
Coagulation factor VII-Fc chimeric proteins for the treatment of hemostatic diseases
|
US7348004B2
(en)
|
2003-05-06 |
2008-03-25 |
Syntonix Pharmaceuticals, Inc. |
Immunoglobulin chimeric monomer-dimer hybrids
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
US9567591B2
(en)
|
2003-05-15 |
2017-02-14 |
Mello Biotechnology, Inc. |
Generation of human embryonic stem-like cells using intronic RNA
|
GB0313132D0
(en)
|
2003-06-06 |
2003-07-09 |
Ich Productions Ltd |
Peptide ligands
|
WO2005009346A2
(en)
|
2003-06-24 |
2005-02-03 |
Mirus Corporation |
Inhibition of gene function by delivery of polynucleotide-based gene expression inhibitors to mammalian cells in vivo
|
GB0316089D0
(en)
|
2003-07-09 |
2003-08-13 |
Xo Bioscience Ltd |
Differentiation method
|
WO2005007819A2
(en)
|
2003-07-09 |
2005-01-27 |
Wisconsin Alumni Research Foundation |
Charge-dynamic polymers and delivery of anionic compounds
|
US8506967B2
(en)
|
2003-07-11 |
2013-08-13 |
Novavax, Inc. |
Functional influenza virus like particles (VLPs)
|
US8592197B2
(en)
|
2003-07-11 |
2013-11-26 |
Novavax, Inc. |
Functional influenza virus-like particles (VLPs)
|
US7575572B2
(en)
|
2003-07-15 |
2009-08-18 |
Spinal Generations, Llc |
Method and device for delivering medicine to bone
|
US20050013870A1
(en)
|
2003-07-17 |
2005-01-20 |
Toby Freyman |
Decellularized extracellular matrix of conditioned body tissues and uses thereof
|
TWI476206B
(en)
|
2003-07-18 |
2015-03-11 |
Amgen Inc |
Specific binding agents to hepatocyte growth factor
|
US7683036B2
(en)
|
2003-07-31 |
2010-03-23 |
Regulus Therapeutics Inc. |
Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
|
DE10335833A1
(en)
|
2003-08-05 |
2005-03-03 |
Curevac Gmbh |
Transfection of blood cells with mRNA for immune stimulation and gene therapy
|
US8668926B1
(en)
|
2003-09-15 |
2014-03-11 |
Shaker A. Mousa |
Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof
|
US7135010B2
(en)
|
2003-09-30 |
2006-11-14 |
Damage Control Surgical Technologies, Inc. |
Method and apparatus for rapid deployment chest drainage
|
CN1890384A
(en)
|
2003-10-06 |
2007-01-03 |
诺瓦提斯公司 |
Use of genetic polymorphisms that associate with efficacy of treatment of inflammatory disease
|
CA2542099A1
(en)
|
2003-10-11 |
2005-04-21 |
Inex Pharmaceuticals Corporation |
Methods and compositions for enhancing innate immunity and antibody dependent cellular cytotoxicity
|
US20050130201A1
(en)
|
2003-10-14 |
2005-06-16 |
Dharmacon, Inc. |
Splint-assisted enzymatic synthesis of polyribounucleotides
|
DE10347710B4
(en)
|
2003-10-14 |
2006-03-30 |
Johannes-Gutenberg-Universität Mainz |
Recombinant vaccines and their use
|
RS58420B1
(en)
|
2003-11-05 |
2019-04-30 |
Roche Glycart Ag |
Cd20 antibodies with increased fc receptor binding affinity and effector function
|
WO2005047536A2
(en)
|
2003-11-13 |
2005-05-26 |
Novartis Ag |
Detection of genomic amplification and deletion in cancer
|
US20070054278A1
(en)
|
2003-11-18 |
2007-03-08 |
Applera Corporation |
Polymorphisms in nucleic acid molecules encoding human enzyme proteins, methods of detection and uses thereof
|
US7699852B2
(en)
|
2003-11-19 |
2010-04-20 |
Zimmer Spine, Inc. |
Fenestrated bone tap and method
|
US20050153333A1
(en)
|
2003-12-02 |
2005-07-14 |
Sooknanan Roy R. |
Selective terminal tagging of nucleic acids
|
WO2005055945A2
(en)
|
2003-12-08 |
2005-06-23 |
Gel-Del Technologies, Inc. |
Mucoadhesive drug delivery devices and methods of making and using thereof
|
US7674884B2
(en)
|
2003-12-10 |
2010-03-09 |
Novimmune S.A. |
Neutralizing antibodies and methods of use thereof
|
US8034619B2
(en)
|
2003-12-19 |
2011-10-11 |
University Of Cincinnati |
Polyamides for nucleic acid delivery
|
SG10201404273QA
(en)
|
2003-12-23 |
2014-10-30 |
Genentech Inc |
Novel anti-il 13 antibodies and uses thereof
|
US20050143336A1
(en)
|
2003-12-30 |
2005-06-30 |
Board Of Regents, The University Of Texas System |
Methods and compositions for improved non-viral gene therapy
|
EP1713514B1
(en)
|
2004-01-28 |
2021-11-24 |
Johns Hopkins University |
Drugs and gene carrier particles that rapidly move through mucous barriers
|
DE602005016218D1
(en)
|
2004-01-30 |
2009-10-08 |
Maxygen Aps |
CONTROLLED READING OF STOP CODONS
|
US7309487B2
(en)
|
2004-02-09 |
2007-12-18 |
George Inana |
Methods and compositions for detecting and treating retinal diseases
|
US20050232919A1
(en)
|
2004-02-12 |
2005-10-20 |
Morphotek, Inc. |
Monoclonal antibodies that specifically block biological activity of a tumor antigen
|
US20070265220A1
(en)
|
2004-03-15 |
2007-11-15 |
City Of Hope |
Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
|
US8398980B2
(en)
|
2004-03-24 |
2013-03-19 |
Chugai Seiyaku Kabushiki Kaisha |
Subtypes of humanized antibody against interleuken-6 receptor
|
WO2005098433A2
(en)
|
2004-04-01 |
2005-10-20 |
Novartis Ag |
Diagnostic assays for alzheimer’s disease
|
WO2005103081A2
(en)
|
2004-04-20 |
2005-11-03 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
ES2246694B1
(en)
|
2004-04-29 |
2007-05-01 |
Instituto Cientifico Y Tecnologico De Navarra, S.A. |
PEGILATED NANOPARTICLES.
|
US20080119645A1
(en)
|
2004-05-05 |
2008-05-22 |
Isis Pharmaceuticals, Inc. |
Amidites and Methods of Rna Synthesis
|
DE602005009954D1
(en)
|
2004-05-12 |
2008-11-06 |
Baxter Int |
NUCLEIC ACID MICRO BEADS, THEIR MANUFACTURE AND DELIVERY
|
WO2005116270A2
(en)
|
2004-05-18 |
2005-12-08 |
Vical Incorporated |
Influenza virus vaccine composition and method of use
|
US20080103053A1
(en)
|
2005-11-22 |
2008-05-01 |
Helicos Biosciences Corporation |
Methods and compositions for sequencing a nucleic acid
|
CA2568772A1
(en)
|
2004-06-01 |
2005-12-15 |
San Diego State University Foundation |
Expression system based on recombinant vesicular stomatitis virus synthesizing t7 rna polymerase
|
CA2569664C
(en)
|
2004-06-07 |
2013-07-16 |
Protiva Biotherapeutics, Inc. |
Lipid encapsulated interfering rna
|
EP1781593B1
(en)
|
2004-06-07 |
2011-12-14 |
Protiva Biotherapeutics Inc. |
Cationic lipids and methods of use
|
US8178656B2
(en)
|
2004-06-11 |
2012-05-15 |
Trustees Of Tufts College |
Silk-based drug delivery system
|
US7527947B2
(en)
|
2004-06-14 |
2009-05-05 |
Novozymes A/S |
Signal peptide for producing a polypeptide
|
WO2006046978A2
(en)
|
2004-06-28 |
2006-05-04 |
Argos Therapeutics, Inc. |
Cationic peptide-mediated transformation
|
JP2008505119A
(en)
|
2004-06-30 |
2008-02-21 |
ネクター セラピューティクス アラバマ,コーポレイション |
Macromolecule-Factor IX Conjugate
|
WO2006093526A2
(en)
|
2004-07-21 |
2006-09-08 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising a modified or non-natural nucleobase
|
DE102004035227A1
(en)
|
2004-07-21 |
2006-02-16 |
Curevac Gmbh |
mRNA mixture for vaccination against tumor diseases
|
US7603349B1
(en)
|
2004-07-29 |
2009-10-13 |
Yahoo! Inc. |
User interfaces for search systems using in-line contextual queries
|
GB0417487D0
(en)
|
2004-08-05 |
2004-09-08 |
Novartis Ag |
Organic compound
|
US7291208B2
(en)
|
2004-08-13 |
2007-11-06 |
Gore Enterprise Holdings, Inc. |
Grooved active and passive adsorbent filters
|
SE0402025D0
(en)
|
2004-08-13 |
2004-08-13 |
Active Biotech Ab |
Treatment of hyperproliferative disease with superantigens in combination with another anticancer agent
|
CA2478458A1
(en)
|
2004-08-20 |
2006-02-20 |
Michael Panzara |
Treatment of pediatric multiple sclerosis
|
MX2007002294A
(en)
|
2004-08-26 |
2007-10-19 |
Engeneic Molecular Delivery Pty Ltd |
Delivering functional nucleic acids to mammalian cells via bacterially derived, intact minicells.
|
DE102004042546A1
(en)
|
2004-09-02 |
2006-03-09 |
Curevac Gmbh |
Combination therapy for immune stimulation
|
US7501486B2
(en)
|
2004-09-07 |
2009-03-10 |
Burnham Institute For Medical Research |
Peptides that selectively home to heart vasculature and related conjugates and methods
|
US8663599B1
(en)
|
2004-10-05 |
2014-03-04 |
Gp Medical, Inc. |
Pharmaceutical composition of nanoparticles
|
US20080075698A1
(en)
|
2004-10-12 |
2008-03-27 |
Tissue Targeting Japan Inc. |
Brain-Localizing Bone Marrow Progenitor cells
|
EP1815206B1
(en)
|
2004-10-13 |
2016-04-06 |
PTC Therapeutics, Inc. |
Compounds for nonsense suppression, and methods for their use
|
US8057821B2
(en)
|
2004-11-03 |
2011-11-15 |
Egen, Inc. |
Biodegradable cross-linked cationic multi-block copolymers for gene delivery and methods of making thereof
|
WO2006047842A2
(en)
|
2004-11-08 |
2006-05-11 |
K.U. Leuven Research And Development |
Modified nucleosides for rna interference
|
US8946444B2
(en)
|
2004-11-23 |
2015-02-03 |
Ptc Therapeutics, Inc. |
Tetrahydrocarbazoles as active agents for inhibiting VEGF production by translational control
|
US7976845B2
(en)
|
2004-11-29 |
2011-07-12 |
The Council Of The Queensland Institute Of Medical Research |
Human cytomegalovirus immunotherapy
|
US7964571B2
(en)
|
2004-12-09 |
2011-06-21 |
Egen, Inc. |
Combination of immuno gene therapy and chemotherapy for treatment of cancer and hyperproliferative diseases
|
WO2006063249A2
(en)
|
2004-12-10 |
2006-06-15 |
Justin Hanes |
Functionalized poly (ether-anhydride) block copolymers
|
WO2006067254A2
(en)
|
2004-12-21 |
2006-06-29 |
Lacer, S.A. |
Method and device for the in vitro diagnosis of familial hypercholesterolemia, based on the detection of mutations in the gene sequence of the low-density lipoprotein receptor (ldlr)
|
WO2006071903A2
(en)
|
2004-12-28 |
2006-07-06 |
Ptc Therapeutics, Inc. |
Cell based methods and systems for the identification of rna regulatory sequences and compounds that modulate their functions
|
US8192718B1
(en)
|
2005-01-04 |
2012-06-05 |
Gp Medical, Inc. |
Pharmaceutical composition of nanoparticles
|
US8187570B1
(en)
|
2005-01-04 |
2012-05-29 |
Gp Medical, Inc. |
Nanoparticles for protein drug delivery
|
US8535702B2
(en)
|
2005-02-01 |
2013-09-17 |
Boston Scientific Scimed, Inc. |
Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility
|
US7404969B2
(en)
|
2005-02-14 |
2008-07-29 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
WO2007086883A2
(en)
|
2005-02-14 |
2007-08-02 |
Sirna Therapeutics, Inc. |
Cationic lipids and formulated molecular compositions containing them
|
EP2287608B1
(en)
|
2005-03-11 |
2014-01-08 |
Firalis SAS |
Biomarkers for cardiovascular side-effects induced by cox-2 inhibitory compounds
|
US8415325B2
(en)
|
2005-03-31 |
2013-04-09 |
University Of Delaware |
Cell-mediated delivery and targeted erosion of noncovalently crosslinked hydrogels
|
WO2006110581A2
(en)
|
2005-04-07 |
2006-10-19 |
Novartis Vaccines And Diagnostics Inc. |
Cancer-related genes
|
EP1865981A2
(en)
|
2005-04-07 |
2007-12-19 |
Chiron Corporation |
Cacna1e in cancer diagnosis, detection and treatment
|
US8273339B2
(en)
|
2005-04-12 |
2012-09-25 |
Nektar Therapeutics |
Polymer-based compositions and conjugates of antimicrobial agents
|
WO2006116458A2
(en)
|
2005-04-26 |
2006-11-02 |
Coley Pharmaceutical Gmbh |
Modified oligoribonucleotide analogs with enhances immunostimulatory activity
|
EP3530736A3
(en)
|
2005-05-09 |
2019-11-06 |
ONO Pharmaceutical Co., Ltd. |
Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
|
US20070072175A1
(en)
|
2005-05-13 |
2007-03-29 |
Biogen Idec Ma Inc. |
Nucleotide array containing polynucleotide probes complementary to, or fragments of, cynomolgus monkey genes and the use thereof
|
US20060265771A1
(en)
|
2005-05-17 |
2006-11-23 |
Lewis David L |
Monitoring microrna expression and function
|
DE102005023170A1
(en)
|
2005-05-19 |
2006-11-23 |
Curevac Gmbh |
Optimized formulation for mRNA
|
AU2006255085A1
(en)
|
2005-06-03 |
2006-12-14 |
Genentech, Inc. |
Method of producing antibodies with modified fucosylation level
|
US7550264B2
(en)
|
2005-06-10 |
2009-06-23 |
Datascope Investment Corporation |
Methods and kits for sense RNA synthesis
|
US9006487B2
(en)
|
2005-06-15 |
2015-04-14 |
Massachusetts Institute Of Technology |
Amine-containing lipids and uses thereof
|
EP1896082B1
(en)
|
2005-06-16 |
2012-12-26 |
Nektar Therapeutics |
Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates
|
US20110182805A1
(en)
|
2005-06-17 |
2011-07-28 |
Desimone Joseph M |
Nanoparticle fabrication methods, systems, and materials
|
US8202835B2
(en)
|
2005-06-17 |
2012-06-19 |
Yitzchak Hillman |
Disease treatment via antimicrobial peptides or their inhibitors
|
KR20080025181A
(en)
|
2005-06-30 |
2008-03-19 |
아케믹스 코포레이션 |
Materials and methods for generation of fully 2'-modified nucleic acid transcripts
|
US8101385B2
(en)
|
2005-06-30 |
2012-01-24 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
US20080220471A1
(en)
|
2005-07-27 |
2008-09-11 |
Genentech, Inc. |
Vectors and Methods Using Same
|
US9012219B2
(en)
|
2005-08-23 |
2015-04-21 |
The Trustees Of The University Of Pennsylvania |
RNA preparations comprising purified modified RNA for reprogramming cells
|
EP4332227A1
(en)
|
2005-08-23 |
2024-03-06 |
The Trustees of the University of Pennsylvania |
Rna containing modified nucleosides and methods of use thereof
|
US20070048741A1
(en)
|
2005-08-24 |
2007-03-01 |
Getts Robert C |
Methods and kits for sense RNA synthesis
|
DE602006020300D1
(en)
|
2005-09-01 |
2011-04-07 |
Celgene Corp |
IMMUNOLOGICAL USES OF IMMUNOMODULATIVE COMPOUNDS FOR A VACCINATE AND THERAPY AGAINST INFECTIOUS DISEASES
|
BRPI0615420A2
(en)
|
2005-09-01 |
2011-05-17 |
Novartis Vaccines & Diagnostic |
multiple vaccination including serogroup c meningococcus
|
US8420605B2
(en)
|
2005-09-07 |
2013-04-16 |
The University Of Strathclyde |
Hydrogel compositions
|
US20120021042A1
(en)
|
2005-09-15 |
2012-01-26 |
Steffen Panzner |
Efficient Method For Loading Amphoteric Liposomes With Nucleic Acid Active Substances
|
DE102005046490A1
(en)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
New nucleic acid molecule comprising promoter, a transcriptable nucleic acid sequence, a first and second nucleic acid sequence for producing modified RNA with transcriptional stability and translational efficiency
|
US20070087437A1
(en)
|
2005-10-14 |
2007-04-19 |
Jifan Hu |
Methods for rejuvenating cells in vitro and in vivo
|
US20070105124A1
(en)
|
2005-11-08 |
2007-05-10 |
Getts Robert C |
Methods and kits for nucleic acid amplification
|
EP1960538A2
(en)
|
2005-11-18 |
2008-08-27 |
Bioline Limited |
A method for enhancing enzymatic dna polymerase reactions
|
EP1973576B1
(en)
|
2005-11-28 |
2019-05-15 |
Genmab A/S |
Recombinant monovalent antibodies and methods for production thereof
|
AU2005338632B2
(en)
|
2005-11-30 |
2010-05-20 |
Epicentre Technologies Corporation |
Selective terminal tagging of nucleic acids
|
TWI389709B
(en)
|
2005-12-01 |
2013-03-21 |
Novartis Ag |
Transdermal therapeutic system
|
ES2564241T3
(en)
|
2005-12-02 |
2016-03-21 |
Glaxosmithkline Biologicals Sa |
Nanoparticles for use in immunogenic compositions
|
US8603457B2
(en)
|
2005-12-02 |
2013-12-10 |
University Of Rochester |
Nonsense suppression and genetic codon alteration by targeted modification
|
US8242081B2
(en)
|
2005-12-06 |
2012-08-14 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
US7579318B2
(en)
|
2005-12-06 |
2009-08-25 |
Centre De La Recherche De La Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
JP2009523410A
(en)
|
2005-12-08 |
2009-06-25 |
ノバルティス アクチエンゲゼルシャフト |
Effect of inhibitors of FGFR3 on gene transcription
|
EP2208786B1
(en)
|
2005-12-13 |
2018-08-01 |
Kyoto University |
Nuclear reprogramming factor
|
WO2007069068A2
(en)
|
2005-12-16 |
2007-06-21 |
Diatos |
Cell penetrating peptide conjugates for delivering nucleic acids into cells
|
WO2007082305A2
(en)
|
2006-01-12 |
2007-07-19 |
Massachusetts Institute Of Technology |
Biodegradable elastomers
|
KR101421745B1
(en)
|
2006-01-13 |
2014-07-22 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
Vaccines and immunotherapeutics using codon optimized il-15 and methods for using the same
|
JP5342881B2
(en)
|
2006-01-27 |
2013-11-13 |
アイシス ファーマシューティカルズ, インコーポレーテッド |
6-modified bicyclic nucleic acid analogues
|
US20070178103A1
(en)
|
2006-01-30 |
2007-08-02 |
Fey Georg H |
CD19-specific immunotoxin and treatment method
|
US8946155B2
(en)
|
2006-02-03 |
2015-02-03 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US8476234B2
(en)
|
2006-02-03 |
2013-07-02 |
Prolor Biotech Inc. |
Long-acting coagulation factors and methods of producing same
|
US9458444B2
(en)
|
2006-02-03 |
2016-10-04 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
DE102006007433A1
(en)
|
2006-02-17 |
2007-08-23 |
Curevac Gmbh |
Immunostimulant adjuvant useful in vaccines against cancer or infectious diseases comprises a lipid-modified nucleic acid
|
KR100859972B1
(en)
|
2006-02-20 |
2008-09-25 |
이화여자대학교 산학협력단 |
Cell membrane-penetrating peptide
|
KR101513732B1
(en)
|
2006-02-21 |
2015-04-21 |
넥타르 테라퓨틱스 |
Segmented degradable polymers and conjugates made therefrom
|
WO2007100789A2
(en)
|
2006-02-24 |
2007-09-07 |
Wyeth |
Gpat3 encodes a mammalian, microsomal acyl-coa:glycerol 3-phosphate acyltransferase
|
AU2007221154A1
(en)
|
2006-02-24 |
2007-09-07 |
Novartis Ag |
Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions
|
US7910152B2
(en)
|
2006-02-28 |
2011-03-22 |
Advanced Cardiovascular Systems, Inc. |
Poly(ester amide)-based drug delivery systems with controlled release rate and morphology
|
CA2641513C
(en)
|
2006-02-28 |
2021-09-21 |
Elan Pharmaceuticals, Inc. |
Methods of treating inflammatory and autoimmune diseases with natalizumab
|
GB0605217D0
(en)
|
2006-03-15 |
2006-04-26 |
Novartis Ag |
Method and compositions for assessing acute rejection
|
WO2007109244A2
(en)
|
2006-03-21 |
2007-09-27 |
Morehouse School Of Medicine |
Novel nanoparticles for delivery of active agents
|
CN101505739A
(en)
|
2006-03-30 |
2009-08-12 |
Ptc医疗公司 |
Methods for the production of functional protein from DNA having a nonsense mutation and the treatment of disorders associated therewith
|
ES2776100T3
(en)
|
2006-03-31 |
2020-07-29 |
Massachusetts Inst Technology |
System for targeted delivery of therapeutic agents
|
EP2007358A4
(en)
|
2006-04-04 |
2012-01-25 |
Stc Unm |
Swellable particles for drug delivery
|
EP1852127A1
(en)
|
2006-05-02 |
2007-11-07 |
Charité - Universitätsmedizin Berlin |
Use of a B-cell-depleting antibody for treatment of polyoma virus infections
|
CA2652280C
(en)
|
2006-05-15 |
2014-01-28 |
Massachusetts Institute Of Technology |
Polymers for functional particles
|
WO2012024613A1
(en)
|
2010-08-19 |
2012-02-23 |
Wintrance Corporation |
Synergistic biomolecule-polymer conjugates
|
US9925151B2
(en)
|
2006-05-24 |
2018-03-27 |
Merck Serono Sa |
Cladribine regimen for treating multiple sclerosis
|
EP2492684B1
(en)
|
2006-06-02 |
2016-12-28 |
President and Fellows of Harvard College |
Protein surface remodeling
|
US8501478B2
(en)
|
2006-06-15 |
2013-08-06 |
University Of Cincinnati |
Trehalose click polymers for delivery of biologically active molecules
|
JP5605895B2
(en)
|
2006-07-04 |
2014-10-15 |
ゲンマブ エー/エス |
CD20 binding molecule for treating COPD
|
US20100015232A1
(en)
|
2006-07-07 |
2010-01-21 |
Aarhus Universitet |
Nanoparticles for nucleic acid delivery
|
CA2655360C
(en)
|
2006-07-12 |
2014-09-16 |
Novartis Ag |
Actinically crosslinkable copolymers for manufacturing contact lenses
|
US20110097261A1
(en)
|
2006-07-20 |
2011-04-28 |
Janatpour Mary J |
Amigo-2-inhibitors for treating, diagnosing or detecting cancer
|
JP5571380B2
(en)
|
2006-07-24 |
2014-08-13 |
ルミナス バイオサイエンシズ,インコーポレイテッド |
Solid nanoparticle formulations of water-insoluble pharmaceutical substances with reduced Ostwald ripening
|
JP2009544754A
(en)
|
2006-07-28 |
2009-12-17 |
アプライド バイオシステムズ, エルエルシー |
Dinucleotide MRNA cap analog
|
DE102006035618A1
(en)
|
2006-07-31 |
2008-02-07 |
Curevac Gmbh |
New nucleic acid useful as immuno-stimulating adjuvant for manufacture of a composition for treatment of cancer diseases e.g. colon carcinomas and infectious diseases e.g. influenza and malaria
|
WO2008014979A2
(en)
|
2006-07-31 |
2008-02-07 |
Curevac Gmbh |
NUCLEIC ACID OF FORMULA (I): GIXmGn, OR (II): CIXmCn, IN PARTICULAR AS AN IMMUNE-STIMULATING AGENT/ADJUVANT
|
MX2009001445A
(en)
|
2006-08-07 |
2009-02-18 |
Genzyme Corp |
Combination therapy.
|
CA2661093A1
(en)
|
2006-08-18 |
2008-02-21 |
Nastech Pharmaceutical Company Inc. |
Dicer substrate rna peptide conjugates and methods for rna therapeutics
|
US8658211B2
(en)
|
2006-08-18 |
2014-02-25 |
Arrowhead Madison Inc. |
Polyconjugates for in vivo delivery of polynucleotides
|
CA2661634C
(en)
|
2006-09-06 |
2017-03-28 |
The Regents Of The University Of California |
Selectively targeted antimicrobial peptides and the use thereof
|
WO2008028946A2
(en)
|
2006-09-07 |
2008-03-13 |
Crucell Holland B.V. |
Human binding molecules capable of neutralizing influenza virus h5n1 and uses thereof
|
EP2061433B1
(en)
|
2006-09-08 |
2011-02-16 |
Johns Hopkins University |
Compositions for enhancing transport through mucus
|
US8454948B2
(en)
|
2006-09-14 |
2013-06-04 |
Medgenics Medical Israel Ltd. |
Long lasting drug formulations
|
GB0619182D0
(en)
|
2006-09-29 |
2006-11-08 |
Leuven K U Res & Dev |
Oligonucleotide arrays
|
AU2007303205A1
(en)
|
2006-10-03 |
2008-04-10 |
Tekmira Pharmaceuticals Corporation |
Lipid containing formulations
|
CA2665343C
(en)
|
2006-10-05 |
2014-12-16 |
The Johns Hopkins University |
Water-dispersible oral, parenteral, and topical formulations for poorly water soluble drugs using smart polymeric nanoparticles
|
DE102006051516A1
(en)
|
2006-10-31 |
2008-05-08 |
Curevac Gmbh |
(Base) modified RNA to increase the expression of a protein
|
US8414927B2
(en)
|
2006-11-03 |
2013-04-09 |
Boston Scientific Scimed, Inc. |
Cross-linked polymer particles
|
US7999087B2
(en)
|
2006-11-15 |
2011-08-16 |
Agilent Technologies, Inc. |
2′-silyl containing thiocarbonate protecting groups for RNA synthesis
|
US8242258B2
(en)
|
2006-12-03 |
2012-08-14 |
Agilent Technologies, Inc. |
Protecting groups for RNA synthesis
|
US8399007B2
(en)
|
2006-12-05 |
2013-03-19 |
Landec Corporation |
Method for formulating a controlled-release pharmaceutical formulation
|
WO2008070118A1
(en)
|
2006-12-05 |
2008-06-12 |
Landec Corporation |
Drug delivery
|
NZ577405A
(en)
|
2006-12-06 |
2012-08-31 |
Novartis Ag |
Vaccines including antigen from four strains of influenza virus
|
US9034348B2
(en)
|
2006-12-11 |
2015-05-19 |
Chi2Gel Ltd. |
Injectable chitosan mixtures forming hydrogels
|
CA2672758C
(en)
|
2006-12-18 |
2019-07-30 |
Acceleron Pharma Inc. |
Activin-actrii antagonists and uses for increasing red blood cell levels
|
US8268586B2
(en)
|
2006-12-21 |
2012-09-18 |
Novozymes, Inc. |
Modified messenger RNA stabilizing sequences for expressing genes in bacterial cells
|
EP2120859B1
(en)
|
2006-12-21 |
2013-11-20 |
Stryker Corporation |
Sustained-release formulations comprising bmp-7 crystals
|
DE102006061015A1
(en)
|
2006-12-22 |
2008-06-26 |
Curevac Gmbh |
Process for the purification of RNA on a preparative scale by HPLC
|
WO2008078180A2
(en)
|
2006-12-22 |
2008-07-03 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
KR101442867B1
(en)
|
2006-12-27 |
2014-09-25 |
넥타르 테라퓨틱스 |
Factor ⅸ moietypolymer conjugates having a releasable linkage
|
US8338166B2
(en)
|
2007-01-04 |
2012-12-25 |
Lawrence Livermore National Security, Llc |
Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
|
DE102007001370A1
(en)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-encoded antibodies
|
WO2008091799A2
(en)
|
2007-01-22 |
2008-07-31 |
The Trustees Of Columbia University In The City Of New York |
Cell-based methods for identifying inhibitors of parkinson's disease-associated lrrk2 mutants
|
EP2423221B1
(en)
|
2007-01-30 |
2015-04-29 |
Epivax, Inc. |
Regulatory t cell epitopes, compositions and uses thereof
|
TW202021980A
(en)
|
2007-02-02 |
2020-06-16 |
美商艾瑟勒朗法瑪公司 |
Variants derived from actriib and uses therefor
|
US8859229B2
(en)
|
2007-02-02 |
2014-10-14 |
Yale University |
Transient transfection with RNA
|
US8126267B2
(en)
|
2007-02-05 |
2012-02-28 |
Albany Medical College |
Methods and apparatuses for analyzing digital images to automatically select regions of interest thereof
|
WO2008096370A2
(en)
|
2007-02-05 |
2008-08-14 |
Natco Pharma Limited |
An efficient and novel purification method of recombinant hg-csf
|
US8333799B2
(en)
|
2007-02-12 |
2012-12-18 |
C. R. Bard, Inc. |
Highly flexible stent and method of manufacture
|
EP2131848A4
(en)
|
2007-02-16 |
2012-06-27 |
Merck Sharp & Dohme |
Compositions and methods for potentiated activity of biologicaly active molecules
|
US8242087B2
(en)
|
2007-02-27 |
2012-08-14 |
K.U.Leuven Research & Development |
Phosphate modified nucleosides useful as substrates for polymerases and as antiviral agents
|
EP1964922A1
(en)
|
2007-03-02 |
2008-09-03 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Improvement of protein production
|
EP2522730A1
(en)
|
2007-03-02 |
2012-11-14 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Improvement of protein production
|
WO2008109712A2
(en)
|
2007-03-05 |
2008-09-12 |
Washington University |
Nanoparticle delivery systems for membrane-integrating peptides
|
EP2125892A2
(en)
|
2007-03-20 |
2009-12-02 |
Millennium Pharmaceuticals, Inc. |
Nucleic acids encoding humanized immunoglobulin that binds a4b7 integrin
|
WO2008118013A2
(en)
|
2007-03-23 |
2008-10-02 |
To-Bbb Holding B.V. |
Targeted intracellular delivery of antiviral agents
|
EP2152358B1
(en)
|
2007-04-27 |
2011-03-02 |
Echo Therapeutics, Inc. |
Skin permeation device for analyte sensing or transdermal drug delivery
|
WO2008134721A1
(en)
|
2007-04-30 |
2008-11-06 |
Smithkline Beecham Corporation |
Methods for administering anti-il-5 antibodies
|
WO2008135855A2
(en)
|
2007-05-03 |
2008-11-13 |
Pfizer Products Inc. |
Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer
|
US7682789B2
(en)
|
2007-05-04 |
2010-03-23 |
Ventana Medical Systems, Inc. |
Method for quantifying biomolecules conjugated to a nanoparticle
|
EP2157982B1
(en)
|
2007-05-04 |
2014-12-17 |
Marina Biotech, Inc. |
Amino acid lipids and uses thereof
|
US8728491B2
(en)
|
2007-05-07 |
2014-05-20 |
Alba Therapeutics Corporation |
Transcutaneous delivery of therapeutic agents
|
JP5296328B2
(en)
|
2007-05-09 |
2013-09-25 |
独立行政法人理化学研究所 |
Single-stranded circular RNA and method for producing the same
|
US8202983B2
(en)
|
2007-05-10 |
2012-06-19 |
Agilent Technologies, Inc. |
Thiocarbon-protecting groups for RNA synthesis
|
JP2010527356A
(en)
|
2007-05-14 |
2010-08-12 |
メディミューン,エルエルシー |
How to reduce eosinophil levels
|
WO2008144365A2
(en)
|
2007-05-17 |
2008-11-27 |
Novartis Ag |
Method for making dry powder compositions containing ds-rna based on supercritical fluid technology
|
KR20100017169A
(en)
|
2007-05-22 |
2010-02-16 |
노파르티스 아게 |
Methods of treating, diagnosing and detecting fgf21-associated disorders
|
CN101802172A
(en)
|
2007-05-30 |
2010-08-11 |
通用医疗公司 |
methods of generating pluripotent cells from somatic cells
|
AU2008259907B2
(en)
|
2007-05-30 |
2014-12-04 |
Northwestern University |
Nucleic acid functionalized nanoparticles for therapeutic applications
|
ES2500515T3
(en)
|
2007-06-19 |
2014-09-30 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Synthesis and use of anti-reverse phosphorothioate analogues of the messenger RNA cap
|
US8880907B2
(en)
|
2007-06-21 |
2014-11-04 |
Schneider Electric It Corporation |
Method and system for determining physical location of equipment
|
EP2173872B1
(en)
|
2007-06-29 |
2014-04-02 |
CellScript, Inc. |
Copy dna and sense rna
|
WO2009015071A1
(en)
|
2007-07-23 |
2009-01-29 |
Dharmacon, Inc. |
Screening of micro-rna cluster inhibitor pools
|
US20090042825A1
(en)
|
2007-08-06 |
2009-02-12 |
Majed Matar |
Composition, method of preparation & application of concentrated formulations of condensed nucleic acids with a cationic lipopolymer
|
US9144546B2
(en)
|
2007-08-06 |
2015-09-29 |
Clsn Laboratories, Inc. |
Nucleic acid-lipopolymer compositions
|
EP2183390A1
(en)
|
2007-08-23 |
2010-05-12 |
Novartis Ag |
Methods for detecting oligonucleotides
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
BRPI0816458A2
(en)
|
2007-09-05 |
2013-03-12 |
Hoffmann La Roche |
anti-cd20 type i and type ii antibody combination therapy
|
US8506928B2
(en)
|
2007-09-07 |
2013-08-13 |
The Regents Of The University Of California |
Methods and compounds for targeting tissues
|
US20110086904A1
(en)
|
2007-09-17 |
2011-04-14 |
The Trustees Of The University Of Pennsylvania |
GENERATION OF HYPERSTABLE mRNAs
|
JP5514727B2
(en)
|
2007-09-26 |
2014-06-04 |
イントレキソン コーポレーション |
Synthetic 5'UTR, expression vector, and method for increasing expression of a transgene
|
US8394763B2
(en)
|
2007-09-26 |
2013-03-12 |
Oregon Health & Science University |
Cyclic undecapeptides and derivatives as multiple sclerosis therapies
|
HUE035101T2
(en)
|
2007-09-28 |
2018-05-02 |
Pfizer |
Cancer Cell Targeting Using Nanoparticles
|
EP2042193A1
(en)
|
2007-09-28 |
2009-04-01 |
Biomay AG |
RNA Vaccines
|
US8470560B2
(en)
|
2007-10-03 |
2013-06-25 |
The United States Of America As Represented By The Secretary Of The Army |
CR-2 binding peptide P28 as molecular adjuvant for DNA vaccines
|
WO2009046739A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating prostate cancer (pca)
|
WO2009046738A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating lung cancer, particularly of non-small lung cancers (nsclc)
|
AU2008314647B2
(en)
|
2007-10-12 |
2013-03-21 |
Massachusetts Institute Of Technology |
Vaccine nanotechnology
|
US20090098118A1
(en)
|
2007-10-15 |
2009-04-16 |
Thomas Friess |
Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent
|
US20110091473A1
(en)
|
2007-10-22 |
2011-04-21 |
Genmab A/S |
Novel antibody therapies
|
RU2531493C2
(en)
|
2007-11-01 |
2014-10-20 |
Юниверсити Оф Рочестер |
Recombinant factor viii, possessing higher stability
|
US20110002934A1
(en)
|
2007-11-09 |
2011-01-06 |
Novartis Ag |
Uses of anti-cd40 antibodies
|
US8470771B2
(en)
|
2007-11-14 |
2013-06-25 |
Institute Of Microbiology, Chinese Academy Of Sciences |
Method and medicament for inhibiting the infection of influenza virus
|
CL2008003561A1
(en)
|
2007-11-30 |
2010-02-05 |
Glaxo Group Ltd |
Il-13 binding construct comprising at least one antibody single domain (dab) grafted onto a monoclonal antibody (mabdab); polynucleotide and host cell; procedure to prepare the construction; pharmaceutical composition comprising it and used to treat cancer or inflammatory diseases.
|
EP2848688A1
(en)
|
2007-12-10 |
2015-03-18 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of factor VII gene
|
CA2708766C
(en)
|
2007-12-11 |
2016-02-02 |
The Scripps Research Institute |
Compositions and methods related to mrna translational enhancer elements
|
AU2008334948B2
(en)
|
2007-12-13 |
2014-11-20 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for prevention or treatment of RSV infection
|
EP2072618A1
(en)
|
2007-12-14 |
2009-06-24 |
Johannes Gutenberg-Universität Mainz |
Use of RNA for reprogramming somatic cells
|
AU2008342956A1
(en)
|
2007-12-21 |
2009-07-09 |
Genentech, Inc. |
Therapy of rituximab-refractory rheumatoid arthritis patients
|
WO2009086558A1
(en)
|
2008-01-02 |
2009-07-09 |
Tekmira Pharmaceuticals Corporation |
Improved compositions and methods for the delivery of nucleic acids
|
EP2248906A4
(en)
|
2008-01-23 |
2012-07-11 |
Ajinomoto Kk |
Method of producing l-amino acid
|
US20100297750A1
(en)
|
2008-01-24 |
2010-11-25 |
Toru Natsume |
Polynucleotide or analogue thereof, and gene expression regulation method using the polynucleotide or the analogue thereof
|
SG188104A1
(en)
|
2008-01-31 |
2013-03-28 |
Curevac Gmbh |
Nucleic acids comprising formula (nuglxmgnnv)a and derivatives thereof as an immunostimulating agents /adjuvants
|
EP2250252A2
(en)
|
2008-02-11 |
2010-11-17 |
Cambridge Enterprise Limited |
Improved reprogramming of mammalian cells, and the cells obtained
|
EP2240155B1
(en)
|
2008-02-13 |
2012-06-06 |
Intarcia Therapeutics, Inc |
Devices, formulations, and methods for delivery of multiple beneficial agents
|
DE102008009920A1
(en)
|
2008-02-15 |
2009-08-20 |
Aj Innuscreen Gmbh |
Mobile device for nucleic acid isolation
|
US8506966B2
(en)
|
2008-02-22 |
2013-08-13 |
Novartis Ag |
Adjuvanted influenza vaccines for pediatric use
|
US20120027813A1
(en)
|
2008-02-22 |
2012-02-02 |
Novartis Vaccines And Diagnostics Srl |
Adjuvanted influenza vaccines for pediatric use
|
US20100004313A1
(en)
|
2008-02-29 |
2010-01-07 |
Tbd |
Modified Poloxamers for Gene Expression and Associated Methods
|
US8524233B2
(en)
|
2008-03-14 |
2013-09-03 |
Biocon Limited & Centro de Immunologia Molecular |
Monoclonal antibody and a method thereof
|
AU2009223313A1
(en)
|
2008-03-14 |
2009-09-17 |
Egen, Inc. |
Biodegradable cross-linked branched poly (alkylene imines)
|
AU2009228163B2
(en)
|
2008-03-28 |
2012-08-30 |
Glaxosmithkline Llc |
Methods of treatment
|
CN102119217B
(en)
|
2008-04-15 |
2015-06-03 |
普洛体维生物治疗公司 |
Novel lipid formulations for nucleic acid delivery
|
WO2009129395A1
(en)
|
2008-04-16 |
2009-10-22 |
Abbott Laboratories |
Cationic lipids and uses thereof
|
WO2009129385A1
(en)
|
2008-04-16 |
2009-10-22 |
Abbott Laboratories |
Cationic lipids and uses thereof
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
WO2009131740A2
(en)
|
2008-04-23 |
2009-10-29 |
Amgen Inc. |
Neutralizing proprotein convertase subtilisin kexin type 9 (pcsk9) variants and uses thereof
|
CA3013503A1
(en)
|
2008-04-25 |
2009-10-29 |
Northwestern University |
Nanostructures suitable for sequestering cholesterol and other molecules
|
AU2009243187C1
(en)
|
2008-04-28 |
2015-12-24 |
President And Fellows Of Harvard College |
Supercharged proteins for cell penetration
|
BRPI0913012B1
(en)
|
2008-04-30 |
2021-12-14 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention |
CHIMERA NUCLEIC ACID CHIMERA, METHODS FOR DETECTING A DENGUE VIRUS ANTIBODY IN A PATIENT SAMPLE, AND FOR PRODUCING VIRAL PARTICLES THAT EXPRESS PRM AND DENGUE VIRUS PROTEINS, USE OF CHIMERIC VIRUS AND FLAVIVIRUSES OR VIRAL PARTICLES
|
US9394538B2
(en)
|
2008-05-07 |
2016-07-19 |
Shi-Lung Lin |
Development of universal cancer drugs and vaccines
|
US8231609B2
(en)
|
2008-05-08 |
2012-07-31 |
Minipumps, Llc |
Drug-delivery pumps and methods of manufacture
|
US8697098B2
(en)
|
2011-02-25 |
2014-04-15 |
South Dakota State University |
Polymer conjugated protein micelles
|
ES2404131T3
(en)
|
2008-05-13 |
2013-05-24 |
University Of Washington |
Diblock copolymers and their complexes with polynucleotides for cell delivery
|
JP5689413B2
(en)
|
2008-05-21 |
2015-03-25 |
ライニッシュ フリードリッヒ−ウィルヘルムズ−ユニバーシタット ボン |
5 'triphosphate oligonucleotide having blunt ends and uses thereof
|
CN102186879A
(en)
|
2008-05-29 |
2011-09-14 |
韩诺生物制约株式会社 |
Modified erythropoietin (epo)polypeptides that exhibit increased protease resistance and pharmaceutical compositions thereof
|
FR2931824B1
(en)
|
2008-05-29 |
2014-11-28 |
Centre Nat Rech Scient |
PROCESS FOR RNA SYNTHESIS THROUGH CHEMICAL.
|
WO2009148528A2
(en)
|
2008-05-30 |
2009-12-10 |
Millennium Pharmaceuticals, Inc. |
Assessment of chromosomal alterations to predict clinical outcome of bortezomib treatment
|
PL215513B1
(en)
|
2008-06-06 |
2013-12-31 |
Univ Warszawski |
New borane phosphate analogs of dinucleotides, their application, RNA particle, method of obtaining RNA and method of obtaining peptides or protein
|
TWI451876B
(en)
|
2008-06-13 |
2014-09-11 |
Lilly Co Eli |
Pegylated insulin lispro compounds
|
SI2285350T1
(en)
|
2008-06-16 |
2018-03-30 |
Pfizer Inc. |
Methods for the preparation of targeting agent functionalized diblock copolymers for use in fabrication of therapeutic nanoparticles
|
WO2010005726A2
(en)
|
2008-06-16 |
2010-01-14 |
Bind Biosciences Inc. |
Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same
|
PT2774608T
(en)
|
2008-06-16 |
2020-01-17 |
Pfizer |
Drug loaded polymeric nanoparticles and methods of making and using same
|
US20100009424A1
(en)
|
2008-07-14 |
2010-01-14 |
Natasha Forde |
Sonoporation systems and methods
|
EP2313085A2
(en)
|
2008-07-15 |
2011-04-27 |
Novartis AG |
Immunogenic amphipathic peptide compositions
|
WO2010009065A2
(en)
|
2008-07-15 |
2010-01-21 |
Novartis Ag |
Amphipathic peptide compositions
|
US20110224447A1
(en)
|
2008-08-18 |
2011-09-15 |
Bowman Keith A |
Novel Lipid Nanoparticles and Novel Components for Delivery of Nucleic Acids
|
AU2009290137A1
(en)
|
2008-09-03 |
2010-03-11 |
Xenome Ltd |
Libraries of peptide conjugates and methods for making them
|
WO2010027512A2
(en)
|
2008-09-06 |
2010-03-11 |
Chemgenes Corporation |
Rna synthesis - phosphoramidites for synthetic rna in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic rna at the 3' - end
|
WO2010027903A2
(en)
|
2008-09-08 |
2010-03-11 |
Fred Hutchinson Cancer Research Center |
Lung cancer diagnosis
|
TW201019963A
(en)
|
2008-09-10 |
2010-06-01 |
Abbott Lab |
Polyethylene glycol lipid conjugates and uses thereof
|
US20100087337A1
(en)
|
2008-09-10 |
2010-04-08 |
Bind Biosciences, Inc. |
High Throughput Fabrication of Nanoparticles
|
AR073295A1
(en)
|
2008-09-16 |
2010-10-28 |
Genentech Inc |
METHODS TO TREAT PROGRESSIVE MULTIPLE SCLEROSIS. MANUFACTURING ARTICLE.
|
US20120021519A1
(en)
|
2008-09-19 |
2012-01-26 |
Presidents And Fellows Of Harvard College |
Efficient induction of pluripotent stem cells using small molecule compounds
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
WO2010042490A1
(en)
|
2008-10-06 |
2010-04-15 |
Boston Medical Center Corporation |
A single lentiviral vector system for induced pluripotent (ips) stem cells derivation
|
ES2475065T3
(en)
|
2008-10-09 |
2014-07-10 |
Tekmira Pharmaceuticals Corporation |
Enhanced amino acids and methods for nucleic acid administration
|
US8535655B2
(en)
|
2008-10-10 |
2013-09-17 |
Polyactiva Pty Ltd. |
Biodegradable polymer—bioactive moiety conjugates
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
US8603532B2
(en)
|
2008-10-20 |
2013-12-10 |
Massachusetts Institute Of Technology |
Nanostructures for drug delivery
|
WO2010047839A1
(en)
|
2008-10-25 |
2010-04-29 |
Aura Biosciences |
Modified plant virus particles and uses therefor
|
CN104910025B
(en)
|
2008-11-07 |
2019-07-16 |
麻省理工学院 |
Alkamine lipid and its purposes
|
KR20220150995A
(en)
|
2008-11-10 |
2022-11-11 |
알닐람 파마슈티칼스 인코포레이티드 |
Novel lipids and compositions for the delivery of therapeutics
|
US8734853B2
(en)
|
2008-11-17 |
2014-05-27 |
University Of North Texas Health Science Center At Fort Worth |
HDL particles for delivery of nucleic acids
|
EP2191840A1
(en)
|
2008-11-28 |
2010-06-02 |
Sanofi-Aventis |
Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan
|
EP2196476A1
(en)
|
2008-12-10 |
2010-06-16 |
Novartis Ag |
Antibody formulation
|
WO2010068866A2
(en)
|
2008-12-12 |
2010-06-17 |
Bind Biosciences |
Therapeutic particles suitable for parenteral administration and methods of making and using same
|
US8512964B2
(en)
|
2008-12-12 |
2013-08-20 |
The Regents Of The University Of California |
Targets for treatment of hypercholesterolemia
|
JP2012512175A
(en)
|
2008-12-15 |
2012-05-31 |
バインド バイオサイエンシズ インコーポレイテッド |
Long-circulating nanoparticles for sustained release of therapeutic agents
|
WO2010080724A1
(en)
|
2009-01-12 |
2010-07-15 |
Merck Sharp & Dohme Corp. |
Novel lipid nanoparticles and novel components for delivery of nucleic acids
|
MX2011007589A
(en)
|
2009-01-16 |
2011-08-17 |
Glaxosmithkline Llc |
Treatment of a cancer using a combination of bendamustine and an anti-cd20 antibody.
|
WO2010084371A1
(en)
|
2009-01-26 |
2010-07-29 |
Mitoprod |
Novel circular interfering rna molecules
|
WO2010087791A1
(en)
|
2009-01-27 |
2010-08-05 |
Utc Power Corporation |
Distributively cooled, integrated water-gas shift reactor and vaporizer
|
EP3243504A1
(en)
|
2009-01-29 |
2017-11-15 |
Arbutus Biopharma Corporation |
Improved lipid formulation
|
US8669085B2
(en)
|
2009-02-05 |
2014-03-11 |
Ut-Battelle, Llc |
Transformation of gram positive bacteria by sonoporation
|
WO2010088927A1
(en)
|
2009-02-09 |
2010-08-12 |
Curevac Gmbh |
Use of pei for the improvement of endosomal release and expression of transfected nucleic acids, complexed with cationic or polycationic compounds
|
US20140141089A1
(en)
|
2009-02-11 |
2014-05-22 |
Colorado School Of Mines |
Nanoparticles, Compositions Thereof, and Methods of Use, and Methods of Making the Same
|
EP2401365B1
(en)
|
2009-02-24 |
2016-04-27 |
The Scripps Research Institute |
Reengineering mrna primary structure for enhanced protein production
|
WO2010102066A1
(en)
|
2009-03-05 |
2010-09-10 |
Bend Research, Inc. |
Dextran polymer powder for inhalation administration of pharmaceuticals
|
WO2010141135A2
(en)
|
2009-03-05 |
2010-12-09 |
Trustees Of Boston University |
Bacteriophages expressing antimicrobial peptides and uses thereof
|
JP2012520085A
(en)
|
2009-03-13 |
2012-09-06 |
エーゲン、インコーポレイテッド |
Compositions and methods for delivery of bioactive RNA
|
PT2414322T
(en)
|
2009-03-20 |
2022-12-07 |
Egen Inc |
Polyamine derivatives
|
WO2010111290A1
(en)
|
2009-03-23 |
2010-09-30 |
University Of Utah Research Foundation |
Methods and compositions related to modified guanine bases for controlling off-target effects in rna interference
|
KR101796906B1
(en)
|
2009-03-24 |
2017-11-10 |
유니버시티 오브 시카고 |
Method for carrying out a reaction
|
JP5622254B2
(en)
|
2009-03-31 |
2014-11-12 |
国立大学法人東京大学 |
Double-stranded ribonucleic acid polyion complex
|
KR20170102039A
(en)
|
2009-04-03 |
2017-09-06 |
유니버시티 오브 시카고 |
Compositions and methods related to Protein A (SpA) variants
|
ES2845212T3
(en)
|
2009-04-13 |
2021-07-26 |
Inst Nat Sante Rech Med |
HPV particles and their uses
|
MX2011010971A
(en)
|
2009-04-17 |
2012-01-19 |
Biogen Idec Inc |
Compositions and methods to treat acute myelogenous leukemia.
|
EP2421563B1
(en)
|
2009-04-22 |
2017-04-12 |
Massachusetts Institute of Technology |
Innate immune suppression enables repeated delivery of long rna molecules
|
MA33279B1
(en)
|
2009-04-27 |
2012-05-02 |
Novartis Ag |
COMPOSITIONS AND METHODS FOR INCREASING MUSCLE GROWTH
|
US8715736B2
(en)
|
2009-04-30 |
2014-05-06 |
Florida Agricultural And Mechanical University |
Nanoparticle formulations for skin delivery
|
WO2010127159A2
(en)
|
2009-04-30 |
2010-11-04 |
Intezyne Technologies, Incorporated |
Polymeric micelles for polynucleotide encapsulation
|
SG10201402054UA
(en)
|
2009-05-05 |
2014-09-26 |
Muthiah Manoharan |
Lipid compositions
|
DE202009007116U1
(en)
|
2009-05-18 |
2010-10-14 |
Amoena Medizin-Orthopädie-Technik GmbH |
Anti decubitus cushions
|
US8574835B2
(en)
|
2009-05-29 |
2013-11-05 |
Life Technologies Corporation |
Scaffolded nucleic acid polymer particles and methods of making and using
|
EP2440556A1
(en)
|
2009-06-10 |
2012-04-18 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of phosphatidylinositol 3-kinase
|
TR201811076T4
(en)
|
2009-06-10 |
2018-08-27 |
Arbutus Biopharma Corp |
Improved lipid formulation.
|
NZ597504A
(en)
|
2009-06-15 |
2013-10-25 |
Alnylam Pharmaceuticals Inc |
Lipid formulated dsrna targeting the pcsk9 gene
|
WO2010151664A2
(en)
|
2009-06-26 |
2010-12-29 |
Massachusetts Institute Of Technology |
Compositions and methods for treating cancer and modulating stress granule formation
|
US9018187B2
(en)
|
2009-07-01 |
2015-04-28 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods for the delivery of therapeutic agents
|
IL292615B2
(en)
|
2009-07-01 |
2023-11-01 |
Protiva Biotherapeutics Inc |
Nucleic acid-lipid particles, compositions comprising the same and uses thereof
|
WO2011000106A1
(en)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Improved cationic lipids and methods for the delivery of therapeutic agents
|
WO2011005799A2
(en)
|
2009-07-06 |
2011-01-13 |
Novartis Ag |
Self replicating rna molecules and uses thereof
|
WO2011012316A2
(en)
|
2009-07-31 |
2011-02-03 |
Ludwig-Maximilians-Universität |
Rna with a combination of unmodified and modified nucleotides for protein expression
|
EP2281579A1
(en)
|
2009-08-05 |
2011-02-09 |
BioNTech AG |
Vaccine composition comprising 5'-Cap modified RNA
|
EP2467357B1
(en)
|
2009-08-20 |
2016-03-30 |
Sirna Therapeutics, Inc. |
Novel cationic lipids with various head groups for oligonucleotide delivery
|
WO2011028938A1
(en)
|
2009-09-02 |
2011-03-10 |
Alnylam Pharmaceuticals, Inc. |
Methods for lowering serum cholestrol in a subject using inhibition of pcsk9
|
US20110053829A1
(en)
|
2009-09-03 |
2011-03-03 |
Curevac Gmbh |
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
|
US20110070227A1
(en)
|
2009-09-18 |
2011-03-24 |
Anna-Marie Novotney-Barry |
Treatment of Autoimmune and Inflammatory Diseases
|
WO2011043913A2
(en)
|
2009-10-08 |
2011-04-14 |
Merck Sharp & Dohme Corp. |
Novel cationic lipids with short lipid chains for oligonucleotide delivery
|
US8859284B2
(en)
|
2009-10-22 |
2014-10-14 |
The United States Of America, As Represented By The Secretary Of The Navy |
Delivery of nanoparticles to neurons
|
CN102712935B
(en)
|
2009-11-04 |
2017-04-26 |
不列颠哥伦比亚大学 |
Nucleic acid-containing lipid particles and related methods
|
US8449916B1
(en)
|
2009-11-06 |
2013-05-28 |
Iowa State University Research Foundation, Inc. |
Antimicrobial compositions and methods
|
WO2011060250A1
(en)
|
2009-11-13 |
2011-05-19 |
Bend Research, Inc. |
Cationic dextran polymer derivatives
|
US9415113B2
(en)
|
2009-11-18 |
2016-08-16 |
University Of Washington |
Targeting monomers and polymers having targeting blocks
|
GB0920304D0
(en)
|
2009-11-20 |
2010-01-06 |
Medical Res Council |
Novel liposome nanoparticles for tumour magnetic resonance imaging
|
US8530429B2
(en)
|
2009-11-24 |
2013-09-10 |
Arch Cancer Therapeutics, Inc. |
Brain tumor targeting peptides and methods
|
NZ600616A
(en)
|
2009-12-01 |
2014-11-28 |
Shire Human Genetic Therapies |
Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
|
US20110245756A1
(en)
|
2009-12-03 |
2011-10-06 |
Rishi Arora |
Devices for material delivery, electroporation, sonoporation, and/or monitoring electrophysiological activity
|
EP4382170A2
(en)
|
2009-12-06 |
2024-06-12 |
Bioverativ Therapeutics Inc. |
Factor viii-fc chimeric and hybrid polypeptides, and methods of use thereof
|
EP2509636B1
(en)
|
2009-12-07 |
2017-07-19 |
Arbutus Biopharma Corporation |
Compositions for nucleic acid delivery
|
US20130189741A1
(en)
|
2009-12-07 |
2013-07-25 |
Cellscript, Inc. |
Compositions and methods for reprogramming mammalian cells
|
KR102171849B1
(en)
|
2009-12-07 |
2020-10-30 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
Rna preparations comprising purified modified rna for reprogramming cells
|
WO2011069529A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Mannose-containing solution for lyophilization, transfection and/or injection of nucleic acids
|
WO2011069528A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Lyophilization of nucleic acids in lactate-containing solutions
|
US8357401B2
(en)
|
2009-12-11 |
2013-01-22 |
Bind Biosciences, Inc. |
Stable formulations for lyophilizing therapeutic particles
|
US9295649B2
(en)
|
2009-12-15 |
2016-03-29 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers
|
EP2512487A4
(en)
|
2009-12-15 |
2013-08-07 |
|
Therapeutic polymeric nanoparticles comprising corticosteroids and methods of making and using same
|
EP2512522A4
(en)
|
2009-12-16 |
2013-09-25 |
Brigham & Womens Hospital |
Particles for multiple agent delivery
|
DE102009058769A1
(en)
|
2009-12-16 |
2011-06-22 |
MagForce Nanotechnologies AG, 10589 |
Temperature-dependent activation of catalytic nucleic acids for controlled drug release
|
CA2784568A1
(en)
|
2009-12-18 |
2011-06-23 |
Martin A. Maier |
Lipid particles for delivery of nucleic acids
|
US20110200582A1
(en)
|
2009-12-23 |
2011-08-18 |
Novartis Ag |
Lipids, lipid compositions, and methods of using them
|
WO2011085231A2
(en)
|
2010-01-08 |
2011-07-14 |
Selecta Biosciences, Inc. |
Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines
|
WO2011088309A1
(en)
|
2010-01-14 |
2011-07-21 |
Regulus Therapeutics Inc. |
Microrna compositions and methods
|
US20130116419A1
(en)
|
2010-01-22 |
2013-05-09 |
Daniel Zewge |
Post-synthetic chemical modification of rna at the 2'-position of the ribose ring via "click" chemistry
|
PL2539451T3
(en)
|
2010-02-24 |
2016-08-31 |
Arrowhead Res Corporation |
Compositions for targeted delivery of sirna
|
WO2011106702A2
(en)
|
2010-02-25 |
2011-09-01 |
The Johns Hopkins University |
Sustained delivery of therapeutic agents to an eye compartment
|
WO2011106086A1
(en)
|
2010-02-25 |
2011-09-01 |
Albert Einstein College Of Medicine Of Yeshiva University |
Pegylated albumin polymers and uses thereof
|
US20130133483A1
(en)
|
2010-03-08 |
2013-05-30 |
University Of Rochester |
Synthesis of Nanoparticles Using Reducing Gases
|
EP2547715A4
(en)
|
2010-03-16 |
2013-10-30 |
Univ Utah Res Found |
Cleavable modifications to reducible poly (amido ethylenimines)s to enhance nucleotide delivery
|
WO2011116072A1
(en)
|
2010-03-16 |
2011-09-22 |
Escape Therapeutics, Inc. |
Hybrid hydrogel scaffold compositions and methods of use
|
WO2011115862A1
(en)
|
2010-03-18 |
2011-09-22 |
Merck Sharp & Dohme Corp. |
Endosomolytic poly(amidoamine) disulfide polymers for the delivery of oligonucleotides
|
US20110230816A1
(en)
|
2010-03-18 |
2011-09-22 |
Tyco Healthcare Group Lp |
Gels for Transdermal Delivery
|
US9149432B2
(en)
|
2010-03-19 |
2015-10-06 |
Massachusetts Institute Of Technology |
Lipid vesicle compositions and methods of use
|
GB201005005D0
(en)
|
2010-03-25 |
2010-05-12 |
Angeletti P Ist Richerche Bio |
New vaccine
|
US8207290B2
(en)
|
2010-03-26 |
2012-06-26 |
Cerulean Pharma Inc. |
Methods and systems for generating nanoparticles
|
JP2013528665A
(en)
|
2010-03-26 |
2013-07-11 |
メルサナ セラピューティックス, インコーポレイテッド |
Modified polymers for delivery of polynucleotides, methods for their production, and methods of their use
|
US20110247090A1
(en)
|
2010-04-02 |
2011-10-06 |
Intrexon Corporation |
Synthetic 5'UTRs, Expression Vectors, and Methods for Increasing Transgene Expression
|
US20110243943A1
(en)
|
2010-04-02 |
2011-10-06 |
Athena Discovery, Inc. |
Treatment using relaxin-fusion proteins with extended in vivo half-lives
|
US8808699B2
(en)
|
2010-04-05 |
2014-08-19 |
The University Of Chicago |
Compositions and methods related to protein A (SpA) antibodies as an enhancer of immune response
|
EP3391877A1
(en)
|
2010-04-08 |
2018-10-24 |
The Trustees of Princeton University |
Preparation of lipid nanoparticles
|
CN104997634A
(en)
|
2010-04-09 |
2015-10-28 |
帕西拉制药有限公司 |
Method for formulating large diameter synthetic membrane vesicles
|
US20130071430A1
(en)
|
2010-04-09 |
2013-03-21 |
The University Of Tokyo |
Microrna-controlled recombinant vaccinia virus and use thereof
|
KR101196667B1
(en)
|
2010-04-15 |
2012-11-02 |
포항공과대학교 산학협력단 |
A DELEVERY SYSTEM OF ANTI-CANCER AGENT USING pH SENSITIVE METAL NANOPARTICLE
|
WO2011130624A2
(en)
|
2010-04-16 |
2011-10-20 |
Immune Disease Institute, Inc. |
Sustained polypeptide expression from synthetic, modified rnas and uses thereof
|
EP2377938A1
(en)
|
2010-04-16 |
2011-10-19 |
Eukarys |
Capping-prone RNA polymerase enzymes and their applications
|
SI2558577T1
(en)
|
2010-04-16 |
2019-05-31 |
Nuevolution A/S |
Bi-functional complexes and methods for making and using such complexes
|
US20130260460A1
(en)
|
2010-04-22 |
2013-10-03 |
Isis Pharmaceuticals Inc |
Conformationally restricted dinucleotide monomers and oligonucleotides
|
CN102884041B
(en)
|
2010-04-28 |
2015-04-15 |
协和发酵麒麟株式会社 |
Cationic lipid
|
MX2012012567A
(en)
|
2010-04-28 |
2012-11-21 |
Kimberly Clark Co |
Method for increasing permeability of an epithelial barrier.
|
US20130156845A1
(en)
|
2010-04-29 |
2013-06-20 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated single stranded rna
|
KR20130100906A
(en)
|
2010-04-30 |
2013-09-12 |
노파르티스 아게 |
Predictive markers useful in the treatment of fragile x syndrome (fxs)
|
WO2011143230A1
(en)
|
2010-05-10 |
2011-11-17 |
Alnylam Pharmaceuticals |
Methods and compositions for delivery of active agents
|
JP2013527856A
(en)
|
2010-05-12 |
2013-07-04 |
プロチバ バイオセラピューティクス インコーポレイティッド |
Cationic lipids and methods of use
|
WO2011141704A1
(en)
|
2010-05-12 |
2011-11-17 |
Protiva Biotherapeutics, Inc |
Novel cyclic cationic lipids and methods of use
|
EP2387999A1
(en)
|
2010-05-21 |
2011-11-23 |
CureVac GmbH |
Histidine-containing solution for transfection and/or injection of nucleic acids and uses thereof
|
EP2575895A2
(en)
|
2010-05-24 |
2013-04-10 |
Merck Sharp & Dohme Corp. |
Novel amino alcohol cationic lipids for oligonucleotide delivery
|
WO2011147086A1
(en)
|
2010-05-26 |
2011-12-01 |
江苏命码生物科技有限公司 |
Microvesicles carrying small interfering rnas, preparation methods and uses thereof
|
JP5957646B2
(en)
|
2010-06-04 |
2016-07-27 |
サーナ・セラピューティクス・インコーポレイテッドSirna Therapeutics,Inc. |
Novel low molecular weight cationic lipids for oligonucleotide delivery
|
WO2011157713A2
(en)
|
2010-06-14 |
2011-12-22 |
F. Hoffmann-La Roche Ag |
Cell-penetrating peptides and uses therof
|
BRPI1001959A2
(en)
|
2010-06-15 |
2012-03-06 |
Instituto De Pesquisas Tecnológicas Do Est. S. Paulo S/a - Ipt |
COLLOIDAL NANOCARCHERS FOR HYDROPHYLIC ASSETS AND PRODUCTION PROCESS
|
WO2011163121A1
(en)
|
2010-06-21 |
2011-12-29 |
Alnylam Pharmaceuticals, Inc. |
Multifunctional copolymers for nucleic acid delivery
|
WO2011163483A2
(en)
|
2010-06-25 |
2011-12-29 |
Massachusetts Institute Of Technology |
Polymers for biomaterials and therapeutics
|
EP2585106A1
(en)
|
2010-06-25 |
2013-05-01 |
Novartis AG |
Combinations of meningococcal factor h binding proteins
|
WO2012000104A1
(en)
|
2010-06-30 |
2012-01-05 |
Protiva Biotherapeutics, Inc. |
Non-liposomal systems for nucleic acid delivery
|
EP2589391B1
(en)
|
2010-07-01 |
2018-11-14 |
Rosetta Exosome Co., Ltd. |
Bacterial cell-derived microvesicles for use in a method of treating cancer
|
AU2011274367B2
(en)
|
2010-07-02 |
2015-04-23 |
The University Of Chicago |
Compositions and methods related to protein A (SpA) variants
|
US9192661B2
(en)
|
2010-07-06 |
2015-11-24 |
Novartis Ag |
Delivery of self-replicating RNA using biodegradable polymer particles
|
BR112013000244A2
(en)
|
2010-07-06 |
2016-05-17 |
Novartis Ag |
lipid liposomes having advantageous pka for administration of rna
|
EP2591114B1
(en)
|
2010-07-06 |
2016-06-08 |
GlaxoSmithKline Biologicals SA |
Immunisation of large mammals with low doses of rna
|
SI3243526T1
(en)
|
2010-07-06 |
2020-02-28 |
Glaxosmithkline Biologicals S.A. |
Delivery of rna to trigger multiple immune pathways
|
WO2012006380A2
(en)
|
2010-07-06 |
2012-01-12 |
Novartis Ag |
Cationic oil-in-water emulsions
|
US9770463B2
(en)
|
2010-07-06 |
2017-09-26 |
Glaxosmithkline Biologicals Sa |
Delivery of RNA to different cell types
|
SI4005592T1
(en)
|
2010-07-06 |
2023-03-31 |
Glaxosmithkline Biologicals S.A. |
Virion-like delivery particles for self-replicating rna molecules
|
MX356527B
(en)
|
2010-07-09 |
2018-06-01 |
Bioverativ Therapeutics Inc |
Factor ix polypeptides and methods of use thereof.
|
EP3508573A1
(en)
|
2010-07-09 |
2019-07-10 |
Bioverativ Therapeutics Inc. |
Systems for factor viii processing and methods thereof
|
US20130177523A1
(en)
|
2010-07-13 |
2013-07-11 |
University Of Utah Research Foundation |
Gold particles and methods of making and using the same in cancer treatment
|
US20130211249A1
(en)
|
2010-07-22 |
2013-08-15 |
The Johns Hopkins University |
Drug eluting hydrogels for catheter delivery
|
GB201012410D0
(en)
|
2010-07-23 |
2010-09-08 |
Medical Res Council |
Intracellular immunity
|
ES2558106T3
(en)
|
2010-07-30 |
2016-02-02 |
Curevac Ag |
Formation of nucleic acid complexes with disulfide-cross-linked cationic components for transfection and immunostimulation
|
WO2012016269A1
(en)
|
2010-08-02 |
2012-02-09 |
Curtin University Of Technology |
Determining location of, and imaging, a subsurface boundary
|
WO2012018881A2
(en)
|
2010-08-03 |
2012-02-09 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for the regulation of rna
|
CA2807552A1
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
US9121065B2
(en)
|
2010-08-09 |
2015-09-01 |
The Trustees Of The University Of Pennsylvania |
Nanoparticle-oligonucleotide hybrid structures and methods of use thereof
|
WO2012019630A1
(en)
|
2010-08-13 |
2012-02-16 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein
|
WO2012024233A2
(en)
|
2010-08-14 |
2012-02-23 |
The Regents Of The University Of California |
Zwitterionic lipids
|
US8829329B2
(en)
|
2010-08-18 |
2014-09-09 |
International Business Machines Corporation |
Solar cell and battery 3D integration
|
US20130142868A1
(en)
|
2010-08-20 |
2013-06-06 |
University Of Washington |
Circumferential Aerosol Device for Delivering Drugs to Olfactory Epithelium and Brain
|
EP2605799A4
(en)
|
2010-08-20 |
2014-02-26 |
Cerulean Pharma Inc |
Conjugates, particles, compositions, and related methods
|
AU2011290471B2
(en)
|
2010-08-20 |
2015-08-20 |
Novartis Ag |
Soluble needle arrays for delivery of influenza vaccines
|
EP2611465A4
(en)
|
2010-08-31 |
2014-06-04 |
Theraclone Sciences Inc |
Human immunodeficiency virus (hiv)-neutralizing antibodies
|
US20130253168A1
(en)
|
2010-08-31 |
2013-09-26 |
Steven L. Colletti |
Novel single chemical entities and methods for delivery of oligonucleotides
|
WO2012031046A2
(en)
|
2010-08-31 |
2012-03-08 |
Novartis Ag |
Lipids suitable for liposomal delivery of protein-coding rna
|
ES2938866T3
(en)
|
2010-08-31 |
2023-04-17 |
Glaxosmithkline Biologicals Sa |
Pegylated liposomes for delivery of RNA encoding immunogen
|
AU2011296062A1
(en)
|
2010-08-31 |
2013-04-04 |
Novartis Ag |
Small liposomes for delivery of immunogen-encoding RNA
|
US9549901B2
(en)
|
2010-09-03 |
2017-01-24 |
The Brigham And Women's Hospital, Inc. |
Lipid-polymer hybrid particles
|
US20130236419A1
(en)
|
2010-09-09 |
2013-09-12 |
The University Of Chicago |
Compositions and methods related to attenuated staphylococcal strains
|
WO2012034067A1
(en)
|
2010-09-09 |
2012-03-15 |
The University Of Chicago |
Methods and compositions involving protective staphylococcal antigens
|
US10307372B2
(en)
|
2010-09-10 |
2019-06-04 |
The Johns Hopkins University |
Rapid diffusion of large polymeric nanoparticles in the mammalian brain
|
US8466122B2
(en)
|
2010-09-17 |
2013-06-18 |
Protiva Biotherapeutics, Inc. |
Trialkyl cationic lipids and methods of use thereof
|
JP5961170B2
(en)
|
2010-09-20 |
2016-08-02 |
サーナ・セラピューティクス・インコーポレイテッドSirna Therapeutics,Inc. |
Novel low molecular weight cationic lipids for oligonucleotide delivery
|
EP2619307A1
(en)
|
2010-09-21 |
2013-07-31 |
RiboxX GmbH |
Method for synthesizing rna using dna template
|
KR20130136983A
(en)
|
2010-09-24 |
2013-12-13 |
말린크로트 엘엘씨 |
Aptamer conjugates for targeting of therapeutic and/or diagnostic nanocarriers
|
WO2012040623A2
(en)
|
2010-09-24 |
2012-03-29 |
The Brigham And Women's Hospital, Inc. |
Nanostructured gels capable of controlled release of encapsulated agents
|
WO2012050975A2
(en)
|
2010-09-29 |
2012-04-19 |
The University Of North Carolina At Chapel Hill |
Novel circular mammalian rna molecules and uses thereof
|
EP2621480B1
(en)
|
2010-09-30 |
2018-08-15 |
Sirna Therapeutics, Inc. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
CN104531812A
(en)
|
2010-10-01 |
2015-04-22 |
现代治疗公司 |
Engineered nucleic acids and methods of use thereof
|
US10078075B2
(en)
|
2011-12-09 |
2018-09-18 |
Vanderbilt University |
Integrated organ-on-chip systems and applications of the same
|
US9782342B2
(en)
|
2010-10-11 |
2017-10-10 |
Wichita State University |
Composite magnetic nanoparticle drug delivery system
|
FI122520B
(en)
|
2010-10-15 |
2012-03-15 |
Vesna Blazevic |
Norovirus capsid and rotavirus VP6 protein for use as a combination vaccine
|
CA2813024A1
(en)
|
2010-10-21 |
2012-04-26 |
Merck Sharp & Dohme Corp. |
Novel low molecular weight cationic lipids for oligonucleotide delivery
|
JP2013545736A
(en)
|
2010-10-29 |
2013-12-26 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
Compositions and methods for inhibition of the PCSK9 gene
|
JP6018575B2
(en)
|
2010-10-29 |
2016-11-02 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
Dengue virus recombinant subunit vaccine
|
CA3054532C
(en)
|
2010-11-05 |
2022-07-12 |
The Johns Hopkins University |
Compositions and methods relating to reduced mucoadhesion
|
WO2012061259A2
(en)
|
2010-11-05 |
2012-05-10 |
Merck Sharp & Dohme Corp. |
Novel low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery
|
CA2811113A1
(en)
|
2010-11-09 |
2012-05-18 |
The Regents Of The University Of California |
Skin permeating and cell entering (space) peptides and methods of use thereof
|
AU2011325893B2
(en)
|
2010-11-12 |
2016-01-14 |
Inovio Pharmaceuticals, Inc |
Consensus prostate antigens nucleic acid molecule encoding the same and vaccine and uses comprising the same
|
CN103380113B
(en)
|
2010-11-15 |
2018-03-30 |
生命科技公司 |
Transfection reagent and its preparation and application containing amine
|
JP5933577B2
(en)
|
2010-11-16 |
2016-06-15 |
セレクタ バイオサイエンシーズ インコーポレーテッドSelecta Biosciences,Inc. |
Immunostimulatory oligonucleotide
|
CN103415620B
(en)
|
2010-11-17 |
2016-10-12 |
艾杜罗生物科技公司 |
Induce the method and composition of the immunne response for EGFRvIII
|
CN107012149A
(en)
|
2010-11-19 |
2017-08-04 |
艾德拉药物股份有限公司 |
Regulate and control immunomodulatory oligonucleotide (IRO) compound of the immune response based on TOLL sample acceptors
|
EP2640400A4
(en)
|
2010-11-19 |
2016-01-20 |
Sirna Therapeutics Inc |
Poly(amide) polymers for the delivery of oligonucleotides
|
WO2012075040A2
(en)
|
2010-11-30 |
2012-06-07 |
Shire Human Genetic Therapies, Inc. |
mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES
|
WO2012072096A1
(en)
|
2010-12-03 |
2012-06-07 |
Biontech Ag |
Method for cellular rna expression
|
CA2821622C
(en)
|
2010-12-16 |
2019-09-03 |
Sprna Gmbh |
Pharmaceutical composition consisting of rna having alkali metal as counter ion and formulated with dications
|
US8501930B2
(en)
|
2010-12-17 |
2013-08-06 |
Arrowhead Madison Inc. |
Peptide-based in vivo siRNA delivery system
|
US8901101B2
(en)
|
2010-12-17 |
2014-12-02 |
Sirna Therapeutics, Inc. |
Membrane lytic poly(amido amine) polymers for the delivery of oligonucleotides
|
AU2011348204B2
(en)
|
2010-12-22 |
2017-03-02 |
President And Fellows Of Harvard College |
Continuous directed evolution
|
ES2605990T3
(en)
|
2010-12-29 |
2017-03-17 |
F. Hoffmann-La Roche Ag |
Small molecule conjugates for intracellular administration of nucleic acids
|
WO2012089225A1
(en)
|
2010-12-29 |
2012-07-05 |
Curevac Gmbh |
Combination of vaccination and inhibition of mhc class i restricted antigen presentation
|
US10364440B2
(en)
|
2011-01-04 |
2019-07-30 |
Brown University |
Nanotubes as carriers of nucleic acids into cells
|
WO2012094574A2
(en)
|
2011-01-06 |
2012-07-12 |
The Johns Hopkins University |
Stabilized polyribonucleotide nanoparticles
|
US20140080766A1
(en)
|
2011-01-07 |
2014-03-20 |
Massachusetts Institute Of Technology |
Compositions and methods for macromolecular drug delivery
|
DK2663548T3
(en)
|
2011-01-11 |
2017-07-24 |
Alnylam Pharmaceuticals Inc |
PEGYLED LIPIDS AND THEIR USE FOR PHARMACEUTICAL SUPPLY
|
CN102068701B
(en)
|
2011-01-18 |
2012-11-07 |
沈阳药科大学 |
Application of cleavable polyethylene glycol (PEG) lipid derivative in preparation
|
US20120189700A1
(en)
|
2011-01-19 |
2012-07-26 |
Zoraida Aguilar |
Nanoparticle Based Immunological Stimulation
|
JP2014505064A
(en)
|
2011-01-26 |
2014-02-27 |
セニックス バイオサイエンス ゲーエムベーハー |
Delivery systems and conjugates for delivering compounds via naturally occurring intracellular transport pathways
|
US10363309B2
(en)
|
2011-02-04 |
2019-07-30 |
Case Western Reserve University |
Targeted nanoparticle conjugates
|
US20140066363A1
(en)
|
2011-02-07 |
2014-03-06 |
Arun K. Bhunia |
Carbohydrate nanoparticles for prolonged efficacy of antimicrobial peptide
|
WO2012116715A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in newborns and infants
|
US20120207840A1
(en)
|
2011-02-10 |
2012-08-16 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment Of Non-Melanoma Skin Cancer
|
BR112013020402A2
(en)
|
2011-02-11 |
2018-09-25 |
Irm Llc |
pcsk9 antagonists
|
AU2012217788A1
(en)
|
2011-02-14 |
2013-08-29 |
Swift Biosciences, Inc. |
Polynucleotide primers and probes
|
WO2012112689A1
(en)
|
2011-02-15 |
2012-08-23 |
The University Of North Carolina At Chapel Hill |
Nanoparticle, liposomes, polymers, agents and proteins modified with reversible linkers
|
CA2827118A1
(en)
|
2011-02-15 |
2012-08-23 |
Merrimack Pharmaceuticals, Inc. |
Compositions and methods for delivering nucleic acid to a cell
|
EP2489371A1
(en)
|
2011-02-18 |
2012-08-22 |
Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria |
Carrier peptides for drug delivery
|
WO2012113413A1
(en)
|
2011-02-21 |
2012-08-30 |
Curevac Gmbh |
Vaccine composition comprising complexed immunostimulatory nucleic acids and antigens packaged with disulfide-linked polyethyleneglycol/peptide conjugates
|
US8846850B2
(en)
|
2011-02-22 |
2014-09-30 |
Rutgers, The State University Of New Jersey |
Amphiphilic macromolecules for nucleic acid delivery
|
JP6091435B2
(en)
|
2011-02-22 |
2017-03-08 |
カリフォルニア インスティチュート オブ テクノロジー |
Protein delivery using adeno-associated virus (AAV) vectors
|
US8696637B2
(en)
|
2011-02-28 |
2014-04-15 |
Kimberly-Clark Worldwide |
Transdermal patch containing microneedles
|
EP2680885B8
(en)
|
2011-03-02 |
2018-07-25 |
GlaxoSmithKline Biologicals SA |
Combination vaccines with lower doses of antigen and/or adjuvant
|
WO2012116714A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in elderly patients
|
CN103502436A
(en)
|
2011-03-07 |
2014-01-08 |
麻省理工学院 |
Methods for transfecting cells with nucleic acids
|
US20120237565A1
(en)
|
2011-03-14 |
2012-09-20 |
Intezyne Technologies, Incorporated |
Pegylated polyplexes containing two or more different polymers for polynucleotide delivery
|
WO2012125680A1
(en)
|
2011-03-16 |
2012-09-20 |
Novartis Ag |
Methods of treating vasculitis using an il-17 binding molecule
|
WO2012125812A1
(en)
|
2011-03-17 |
2012-09-20 |
Novartis Ag |
Fgfr and ligands thereof as biomarkers for breast cancer in hr positive subjects
|
US20140212503A1
(en)
|
2011-03-17 |
2014-07-31 |
Hyukjin Lee |
Delivery system
|
CN102204920B
(en)
|
2011-03-18 |
2013-03-20 |
海南本创医药科技有限公司 |
Solid preparation of sodium aspirin and sodium pravastatin medicinal composition
|
WO2012129483A1
(en)
|
2011-03-24 |
2012-09-27 |
Novartis Ag |
Adjuvant nanoemulsions with phospholipids
|
WO2012129648A1
(en)
|
2011-03-25 |
2012-10-04 |
University Of Guelph |
Enhancing protein expression of adeno-associated virus vectors
|
WO2012135025A2
(en)
|
2011-03-28 |
2012-10-04 |
Massachusetts Institute Of Technology |
Conjugated lipomers and uses thereof
|
JP2014510533A
(en)
|
2011-03-28 |
2014-05-01 |
ノバルティス アーゲー |
Markers associated with cyclin-dependent kinase inhibitors
|
US9795679B2
(en)
|
2011-03-31 |
2017-10-24 |
Ingell Technologies Holding B.V. |
Biodegradable compositions suitable for controlled release
|
EP2691079B1
(en)
|
2011-03-31 |
2020-06-24 |
Ingell Technologies Holding B.V. |
Biodegradable compositions suitable for controlled release
|
WO2012135805A2
(en)
|
2011-03-31 |
2012-10-04 |
modeRNA Therapeutics |
Delivery and formulation of engineered nucleic acids
|
WO2012138453A1
(en)
|
2011-04-03 |
2012-10-11 |
The General Hospital Corporation |
Efficient protein expression in vivo using modified rna (mod-rna)
|
EP2694524B1
(en)
|
2011-04-04 |
2016-05-18 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
2'-o-aminooxymethyl nucleoside derivatives for use in the synthesis and modification of nucleosides, nucleotides and oligonucleotides
|
WO2012142132A1
(en)
|
2011-04-11 |
2012-10-18 |
Life Technologies Corporation |
Polymer particles and methods of making and using same
|
EP2696855B1
(en)
|
2011-04-13 |
2021-06-02 |
The Trustees Of The University Of Pennsylvania |
Coated mesoporous nanoparticles
|
WO2013158127A1
(en)
|
2012-04-16 |
2013-10-24 |
Molecular Transfer, Inc. |
Agents for improved delivery of nucleic acids to eukaryotic cells
|
US20140178894A1
(en)
|
2011-04-20 |
2014-06-26 |
Novartis Forschungsstiftung, Zweigniederlassung |
Culture medium suitable for the culture of undifferentiated cells
|
EA034702B1
(en)
|
2011-04-26 |
2020-03-10 |
Молекулар Экспресс, Инк. |
Liposomal compositions
|
US20160272697A2
(en)
|
2011-04-28 |
2016-09-22 |
The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. |
Neutralizing Antibodies to Nipah and Hendra Virus
|
EP2701686A4
(en)
|
2011-04-28 |
2014-11-05 |
Stc Unm |
Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery and methods of using same
|
KR102112002B1
(en)
|
2011-04-29 |
2020-05-18 |
셀렉타 바이오사이언시즈, 인크. |
Tolerogenic synthetic nanocarriers to reduce immune responses to therapeutic proteins
|
WO2012149246A1
(en)
|
2011-04-29 |
2012-11-01 |
Novartis Ag |
Methods of treating squamous cell carcinoma related applications
|
US20120283503A1
(en)
|
2011-04-29 |
2012-11-08 |
The Johns Hopkins University |
Nanoparticle loaded stem cells and their use in mri guided hyperthermia
|
ES2957478T3
(en)
|
2011-05-02 |
2024-01-19 |
Univ Wayne State |
A protein-induced pluripotent stem cell technology and uses thereof
|
UA116189C2
(en)
|
2011-05-02 |
2018-02-26 |
Мілленніум Фармасьютікалз, Інк. |
FORMULATION FOR ANTI-α4β7 ANTIBODY
|
EP3409112B1
(en)
|
2011-05-04 |
2022-07-27 |
The University of Nottingham |
Novel polymers which resist bacterial attachment
|
US8945588B2
(en)
|
2011-05-06 |
2015-02-03 |
The University Of Chicago |
Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
|
EP2707116A1
(en)
|
2011-05-10 |
2014-03-19 |
Basf Se |
Oil-in-water emulsions
|
EP2707033A1
(en)
|
2011-05-11 |
2014-03-19 |
Ramot at Tel Aviv University, Ltd. |
Targeted polymeric conjugates and uses thereof
|
WO2012153338A2
(en)
|
2011-05-12 |
2012-11-15 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Liposomes comprising polymer-conjugated lipids and related uses
|
WO2012152910A1
(en)
|
2011-05-12 |
2012-11-15 |
Helmut Vockner |
Novel pharmaceutical formulation
|
PT2707385T
(en)
|
2011-05-13 |
2017-12-19 |
Glaxosmithkline Biologicals Sa |
Pre-fusion rsv f antigens
|
US8691750B2
(en)
|
2011-05-17 |
2014-04-08 |
Axolabs Gmbh |
Lipids and compositions for intracellular delivery of biologically active compounds
|
US8978170B2
(en)
|
2011-05-20 |
2015-03-17 |
Kohler Co. |
Toilet installation system and method
|
JP2014516531A
(en)
|
2011-05-25 |
2014-07-17 |
ノバルティス アーゲー |
Biomarkers for lung cancer
|
US20120302940A1
(en)
|
2011-05-26 |
2012-11-29 |
Jackson State University |
Popcorn Shape Gold Nanoparticle For Targeted Diagnosis, Photothermal Treatment and In-Situ Monitoring Therapy Response for Cancer and Multiple Drug Resistance Bacteria
|
US20140308363A1
(en)
|
2011-05-31 |
2014-10-16 |
Bind Therapeutics, Inc. |
Drug loaded polymeric nanoparticles and methods of making and using same
|
SG194800A1
(en)
|
2011-06-02 |
2013-12-30 |
Novartis Ag |
Biomarkers for hedgehog inhibitor therapy
|
ES2685333T3
(en)
|
2011-06-02 |
2018-10-08 |
The Regents Of The University Of California |
Membrane encapsulated nanoparticles and method of use
|
WO2012168259A1
(en)
|
2011-06-06 |
2012-12-13 |
Novartis Forschungsstiftung, Zweigniederlassung |
Protein tyrosine phosphatase, non-receptor type 11 (ptpn11) and triple-negative breast cancer
|
KR102128248B1
(en)
|
2011-06-08 |
2020-07-01 |
샤이어 휴먼 지네틱 테라피즈 인크. |
Lipid nanoparticle compositions and methods for mrna delivery
|
DK2718269T3
(en)
|
2011-06-08 |
2018-04-09 |
Translate Bio Inc |
SPLITLY LIPIDS
|
CN102813929B
(en)
|
2011-06-09 |
2014-04-09 |
沈阳药科大学 |
Low-concentration polyethylene glycol-lipid (PEG-lipid) derivative and application thereof
|
WO2012170607A2
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Use of pcsk9 antagonists
|
US8636696B2
(en)
|
2011-06-10 |
2014-01-28 |
Kimberly-Clark Worldwide, Inc. |
Transdermal device containing microneedles
|
WO2012168491A1
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Pharmaceutical formulations of pcsk9 antagonists
|
US8916696B2
(en)
|
2011-06-12 |
2014-12-23 |
City Of Hope |
Aptamer-mRNA conjugates for targeted protein or peptide expression and methods for their use
|
GB2497719A
(en)
*
|
2011-06-14 |
2013-06-26 |
Univ Leicester |
Inhibitors of lipoprotein receptor degradation
|
WO2012172495A1
(en)
|
2011-06-14 |
2012-12-20 |
Novartis Ag |
Compositions and methods for antibodies targeting tem8
|
CN103717249B
(en)
|
2011-06-15 |
2017-03-22 |
克洛恩泰克制药股份公司 |
Injection needle and device
|
US20140193408A1
(en)
|
2011-06-16 |
2014-07-10 |
Novartis Ag |
Soluble proteins for use as therapeutics
|
KR20140047069A
(en)
|
2011-06-20 |
2014-04-21 |
유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 |
Computationally optimized broadly reactive antigens for h1n1 influenza
|
US9862926B2
(en)
|
2011-06-27 |
2018-01-09 |
Cellscript, Llc. |
Inhibition of innate immune response
|
KR102171142B1
(en)
|
2011-06-28 |
2020-10-28 |
이노비오 파마수티컬즈, 인크. |
A miniminally invasive dermal electroporation device
|
HUE040276T2
(en)
|
2011-07-01 |
2019-02-28 |
Novartis Ag |
Method for treating metabolic disorders
|
EP2729182A4
(en)
|
2011-07-04 |
2014-12-24 |
Commw Scient Ind Res Org |
Nucleic acid complex
|
WO2013006834A1
(en)
|
2011-07-06 |
2013-01-10 |
Novartis Ag |
Oil-in-water emulsions that contain nucleic acids
|
EP3854413A1
(en)
|
2011-07-06 |
2021-07-28 |
GlaxoSmithKline Biologicals SA |
Immunogenic combination compositions and uses thereof
|
JP6120839B2
(en)
|
2011-07-06 |
2017-04-26 |
ノバルティス アーゲー |
Cationic oil-in-water emulsion
|
SG10201605537XA
(en)
|
2011-07-06 |
2016-09-29 |
Novartis Ag |
Liposomes having useful n:p ratio for delivery of rna molecules
|
CA2841047A1
(en)
|
2011-07-06 |
2013-01-10 |
Novartis Ag |
Immunogenic compositions and uses thereof
|
EP2729501A2
(en)
|
2011-07-07 |
2014-05-14 |
Life Technologies Corporation |
Polymer particles, nucleic acid polymer particles and methods of making and using the same
|
DK2729462T3
(en)
|
2011-07-08 |
2018-01-08 |
Bayer Ip Gmbh |
PROCEDURE FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILY ACID DIAMIDE DERIVATIVES BY REPLACING PYRAZOLIC ACIDS WITH ANTHRANIC ACID ESTERS
|
WO2013009717A1
(en)
|
2011-07-10 |
2013-01-17 |
Elisabet De Los Pinos |
Virion derived protein nanoparticles for delivering diagnostic or therapeutic agents for the treatment of skin-related diseases
|
US20130012566A1
(en)
|
2011-07-10 |
2013-01-10 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment of Alopecia
|
US9617392B2
(en)
|
2011-07-10 |
2017-04-11 |
President And Fellows Of Harvard College |
Compositions and methods for self-assembly of polymers with complementary macroscopic and microscopic scale units
|
US20140148503A1
(en)
|
2011-07-20 |
2014-05-29 |
University Of Iowa Research Foundation |
Nucleic acid aptamers
|
GB2492999A
(en)
|
2011-07-20 |
2013-01-23 |
Univ Central Lancashire |
Neutron detector
|
ES2670944T3
(en)
|
2011-07-21 |
2018-06-04 |
Croda International Plc |
Branched polyether polyamide block copolymers and methods of preparing and using them
|
WO2013016058A1
(en)
|
2011-07-22 |
2013-01-31 |
Merck Sharp & Dohme Corp. |
Novel bis-nitrogen containing cationic lipids for oligonucleotide delivery
|
EP2736921B1
(en)
|
2011-07-25 |
2018-06-27 |
GlaxoSmithKline Biologicals SA |
Compositions and methods for assessing functional immunogenicity of parvovirus vaccines
|
US9493549B2
(en)
|
2011-07-25 |
2016-11-15 |
The Rockefeller University |
Antibodies directed toward the HIV-1 GP120 CD4 binding site with increased potency and breadth
|
MX2014001142A
(en)
|
2011-07-29 |
2014-02-27 |
Selecta Biosciences Inc |
Synthetic nanocarriers that generate humoral and cytotoxic t lymphocyte (ctl) immune responses.
|
CA2845259A1
(en)
|
2011-08-15 |
2013-02-21 |
The University Of Chicago |
Compositions and methods related to antibodies to staphylococcal protein a
|
CA2842039A1
(en)
|
2011-08-26 |
2013-03-07 |
Arrowhead Research Corporation |
Poly(vinyl ester) polymers for in vivo nucleic acid delivery
|
DK2750707T3
(en)
|
2011-08-31 |
2019-02-11 |
Glaxosmithkline Biologicals Sa |
PEGYLED LIPOSOMES FOR DELIVERING IMMUNOGEN-CODING RNA
|
US9126966B2
(en)
|
2011-08-31 |
2015-09-08 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use thereof
|
US8889657B2
(en)
|
2011-08-31 |
2014-11-18 |
Mallinckrodt Llc |
Nanoparticle PEG modification with H-phosphonates
|
CA2845798A1
(en)
|
2011-09-01 |
2013-03-07 |
Irm Llc |
Compounds and compositions as pdgfr kinase inhibitors
|
WO2013030778A2
(en)
|
2011-09-02 |
2013-03-07 |
Novartis Ag |
Organic compositions to treat hsf1-related diseases
|
EP2755986A4
(en)
|
2011-09-12 |
2015-05-20 |
Moderna Therapeutics Inc |
Engineered nucleic acids and methods of use thereof
|
WO2013039861A2
(en)
|
2011-09-12 |
2013-03-21 |
modeRNA Therapeutics |
Engineered nucleic acids and methods of use thereof
|
WO2013038375A2
(en)
|
2011-09-14 |
2013-03-21 |
Novartis Ag |
Methods for making saccharide-protein glycoconjugates
|
EP2747761A1
(en)
|
2011-09-22 |
2014-07-02 |
Bind Therapeutics, Inc. |
Methods of treating cancers with therapeutic nanoparticles
|
WO2013072929A2
(en)
|
2011-09-23 |
2013-05-23 |
Indian Institute Of Technology |
Nanop article based cosmetic composition
|
JO3476B1
(en)
|
2011-09-26 |
2020-07-05 |
Novartis Ag |
Fusion proteins for treating metabolic disorders
|
TW201315742A
(en)
|
2011-09-26 |
2013-04-16 |
Novartis Ag |
Dual fuction proteins for treating metabolic disorders
|
EP2760477B1
(en)
|
2011-09-27 |
2018-08-08 |
Alnylam Pharmaceuticals, Inc. |
Di-aliphatic substituted pegylated lipids
|
WO2013045505A1
(en)
|
2011-09-28 |
2013-04-04 |
Novartis Ag |
Biomarkers for raas combination therapy
|
RU2707251C2
(en)
|
2011-10-03 |
2019-11-25 |
Модерна Терапьютикс, Инк. |
Modified nucleosides, nucleotides and nucleic acids and use thereof
|
EP2768530A1
(en)
|
2011-10-11 |
2014-08-27 |
Novartis AG |
Recombinant self-replicating polycistronic rna molecules
|
WO2013055971A1
(en)
|
2011-10-11 |
2013-04-18 |
Arizona Board Of Regents For And On Behalf Of Arizona State University |
Polymers for delivering a substance into a cell
|
WO2013055331A1
(en)
|
2011-10-12 |
2013-04-18 |
The Curators Of The University Of Missouri |
Pentablock polymers
|
WO2014066811A1
(en)
|
2012-10-25 |
2014-05-01 |
The Johns Hopkins University |
Bioreducible poly (b-amino ester)s for sirna delivery
|
EP2765997A4
(en)
|
2011-10-14 |
2015-06-24 |
Stc Unm |
Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery including transdermal delivery of cargo and methods thereof
|
EP2766033B1
(en)
|
2011-10-14 |
2019-11-20 |
Novartis AG |
Antibodies and methods for wnt pathway-related diseases
|
US8969545B2
(en)
|
2011-10-18 |
2015-03-03 |
Life Technologies Corporation |
Alkynyl-derivatized cap analogs, preparation and uses thereof
|
EP2768571B1
(en)
|
2011-10-18 |
2023-02-22 |
Micell Technologies, Inc. |
Drug delivery medical device
|
KR102011048B1
(en)
|
2011-10-18 |
2019-08-14 |
다이서나 파마수이티컬, 인크. |
Amine cationic lipids and uses thereof
|
WO2013057715A1
(en)
|
2011-10-20 |
2013-04-25 |
Novartis Ag |
Adjuvanted influenza b virus vaccines for pediatric priming
|
CA2852268C
(en)
|
2011-10-20 |
2020-08-25 |
Novartis Ag |
Biomarkers predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment
|
EP3915545A1
(en)
|
2011-10-25 |
2021-12-01 |
The University of British Columbia |
Limit size lipid nanoparticles and related methods
|
US20130110043A1
(en)
|
2011-10-26 |
2013-05-02 |
Nanopass Technologies Ltd. |
Microneedle Intradermal Drug Delivery Device with Auto-Disable Functionality
|
EP3574950B1
(en)
|
2011-10-27 |
2021-02-17 |
Sorrento Therapeutics, Inc. |
Transdermal delivery of high viscosity bioactive agents
|
KR102272498B1
(en)
|
2011-10-27 |
2021-07-06 |
메사추세츠 인스티튜트 오브 테크놀로지 |
Amino acid derivatives functionalized on the n-terminal capable of forming drug incapsulating microspheres
|
KR101759694B1
(en)
|
2011-10-28 |
2017-07-19 |
인테그리티 바이오, 아이엔씨. |
Protein formulations containing amino acids
|
WO2013062140A1
(en)
|
2011-10-28 |
2013-05-02 |
Kyoto University |
Method for efficiently inducing differentiation of pluripotent stem cells into hepatic lineage cells
|
JP2014534864A
(en)
|
2011-10-28 |
2014-12-25 |
プレサージュ バイオサイエンシズ,インコーポレイテッド |
Drug delivery method
|
LT3091029T
(en)
|
2011-10-31 |
2023-02-27 |
F. Hoffmann-La Roche Ag |
Anti-il13 antibody formulations
|
EP3424564A1
(en)
|
2011-10-31 |
2019-01-09 |
Mallinckrodt LLC |
Combinational liposome compositions for cancer therapy
|
US9579338B2
(en)
|
2011-11-04 |
2017-02-28 |
Nitto Denko Corporation |
Method of producing lipid nanoparticles for drug delivery
|
AU2012356239B2
(en)
|
2011-11-04 |
2016-09-22 |
Nitto Denko Corporation |
Method of producing lipid nanoparticles for drug delivery
|
RU2014122602A
(en)
|
2011-11-04 |
2015-12-10 |
Новартис Аг |
CONSTRUCTIONS BASED ON A PROTEIN RELATED TO LOW DENSITY LIPOPROTEINS, 6 (LRP6), AND EXISTING SEMI-PERIOD EXTENSION
|
WO2013067537A1
(en)
|
2011-11-04 |
2013-05-10 |
Univertiy Of Notre Dame Du Lac |
Nanoparticle-based drug delivery
|
EP2773696B1
(en)
|
2011-11-04 |
2017-07-26 |
Agency For Science, Technology And Research |
Self-assembled composite ultrasmall peptide-polymer hydrogels
|
US20130115247A1
(en)
|
2011-11-05 |
2013-05-09 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Radioisotopes For The Diagnosis And Treatment Of Malignant And Systemic Disease And The Monitoring Of Therapy
|
US20130116408A1
(en)
|
2011-11-05 |
2013-05-09 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Radioisotopes For The Diagnosis And Treatment Of Malignant And Systemic Disease And The Monitoring Of Therapy
|
US20140314787A1
(en)
|
2011-11-08 |
2014-10-23 |
Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute |
Treatment for neurodegenerative diseases
|
US20140287510A1
(en)
|
2011-11-08 |
2014-09-25 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute |
Rod cell-specific promoter
|
US9849087B2
(en)
|
2011-11-08 |
2017-12-26 |
The Board Of Trustees Of The University Of Arkansas |
Methods and compositions for X-ray induced release from pH sensitive liposomes
|
EP2776838A1
(en)
|
2011-11-08 |
2014-09-17 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research |
Early diagnostic of neurodegenerative diseases
|
US9581590B2
(en)
|
2011-11-09 |
2017-02-28 |
Board Of Trustees Of Michigan State University |
Metallic nanoparticle synthesis with carbohydrate capping agent
|
RU2019139064A
(en)
|
2011-11-11 |
2020-01-27 |
Вэриэйшн Биотекнолоджиз Инк. |
Compositions and methods for the treatment of cytomegalovirus
|
WO2013071047A1
(en)
|
2011-11-11 |
2013-05-16 |
Children's Medical Center Corporation |
Compositions and methods for in vitro transcription of rna
|
CA2855826A1
(en)
|
2011-11-14 |
2013-05-23 |
Novartis Ag |
Immunogenic complexes of polyanionic carbomers and env polypeptides and methods of manufacture and use thereof
|
MX2014005927A
(en)
|
2011-11-15 |
2014-06-05 |
Novartis Ag |
Combination of a phosphoinositide 3-kinase inhibitor and a modulator of the janus kinase 2-signal transducer and activator of transcription 5 pathway.
|
RU2642664C2
(en)
|
2011-11-18 |
2018-01-25 |
Ридженерон Фармасьютикалз, Инк. |
Polymeric protein microparticles
|
EP2783014A1
(en)
|
2011-11-21 |
2014-10-01 |
Novartis AG |
Methods of treating psoriatic arthritis (psa) using il-17 antagonists and psa response or non- response alleles
|
WO2013078199A2
(en)
|
2011-11-23 |
2013-05-30 |
Children's Medical Center Corporation |
Methods for enhanced in vivo delivery of synthetic, modified rnas
|
US20150037428A1
(en)
|
2011-11-29 |
2015-02-05 |
The University Of North Carolina At Chapel Hill |
Geometrically engineered particles and methods for modulating macrophage or immune responses
|
US9364549B2
(en)
|
2011-11-30 |
2016-06-14 |
Andreas Voigt |
Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
|
CA2857502C
(en)
|
2011-11-30 |
2019-08-13 |
3M Innovative Properties Company |
Microneedle device including a peptide therapeutic agent and an amino acid and methods of making and using the same
|
CA2854054C
(en)
|
2011-12-02 |
2020-05-12 |
Pegasus Laboratories, Inc. |
Amphipathic lipid-based sustained release compositions
|
WO2013082529A1
(en)
|
2011-12-02 |
2013-06-06 |
Yale University |
Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery
|
US20130142781A1
(en)
|
2011-12-02 |
2013-06-06 |
Invivo Therapeutics Corporation |
Peg based hydrogel for peripheral nerve injury applications and compositions and method of use of synthetic hydrogel sealants
|
RU2691027C2
(en)
|
2011-12-05 |
2019-06-07 |
Фэктор Байосайенс Инк. |
Methods and preparations for transfection of cells
|
US9814867B2
(en)
|
2011-12-05 |
2017-11-14 |
Nano Precision Medical, Inc. |
Device having titania nanotube membrane for drug delivery
|
US8497124B2
(en)
|
2011-12-05 |
2013-07-30 |
Factor Bioscience Inc. |
Methods and products for reprogramming cells to a less differentiated state
|
US9463247B2
(en)
|
2011-12-07 |
2016-10-11 |
Alnylam Pharmaceuticals, Inc. |
Branched alkyl and cycloalkyl terminated biodegradable lipids for the delivery of active agents
|
US20140308304A1
(en)
|
2011-12-07 |
2014-10-16 |
Alnylam Pharmaceuticals, Inc. |
Lipids for the delivery of active agents
|
AU2012347637B2
(en)
|
2011-12-07 |
2017-09-14 |
Alnylam Pharmaceuticals, Inc. |
Biodegradable lipids for the delivery of active agents
|
GB201121070D0
(en)
|
2011-12-07 |
2012-01-18 |
Isis Innovation |
composition for delivery of biotherapeutics
|
WO2013086502A1
(en)
|
2011-12-09 |
2013-06-13 |
President And Fellows Of Harvard College |
Organ chips and uses thereof
|
US9725687B2
(en)
|
2011-12-09 |
2017-08-08 |
President And Fellows Of Harvard College |
Integrated human organ-on-chip microphysiological systems
|
WO2013086526A1
(en)
|
2011-12-09 |
2013-06-13 |
The Regents Of The University Of California |
Liposomal drug encapsulation
|
US9839616B2
(en)
|
2011-12-12 |
2017-12-12 |
Kyowa Hakko Kirin Co., Ltd. |
Lipid nano particles comprising cationic lipid for drug delivery system
|
US9750795B2
(en)
|
2011-12-12 |
2017-09-05 |
The Trustees Of The University Of Pennsylvania |
Proteins comprising MRSA PBP2a and fragments thereof, nucleic acids encoding the same, and compositions and their use to prevent and treat MRSA infections
|
US20140045913A1
(en)
|
2011-12-12 |
2014-02-13 |
Kyowa Hakko Kirin Co., Ltd. |
Lipid nano particles comprising combination of cationic lipid
|
US9844598B2
(en)
|
2011-12-13 |
2017-12-19 |
Engeneic Molecular Delivery Pty Ltd |
Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors
|
EP2604253A1
(en)
|
2011-12-13 |
2013-06-19 |
Otto Glatter |
Water-in-oil emulsions and methods for their preparation
|
US20150000936A1
(en)
|
2011-12-13 |
2015-01-01 |
Schlumberger Technology Corporation |
Energization of an element with a thermally expandable material
|
EP2791364A4
(en)
|
2011-12-14 |
2015-11-11 |
Moderna Therapeutics Inc |
Methods of responding to a biothreat
|
US20140343129A1
(en)
|
2011-12-14 |
2014-11-20 |
Moderna Therapeutics, Inc. |
Modified nucleic acids, and acute care uses thereof
|
WO2013087083A1
(en)
|
2011-12-15 |
2013-06-20 |
Biontech Ag |
Particles comprising single stranded rna and double stranded rna for immunomodulation
|
WO2013090897A1
(en)
|
2011-12-15 |
2013-06-20 |
The Trustees Of The University Of Pennsylvania |
Using adaptive immunity to detect drug resistance
|
EA201491185A1
(en)
|
2011-12-16 |
2015-05-29 |
Массачусетс Инститьют Оф Текнолоджи |
ALPHA-AMINOAMIDINE POLYMERS AND THEIR APPLICATION
|
KR20140102759A
(en)
|
2011-12-16 |
2014-08-22 |
모더나 세라퓨틱스, 인코포레이티드 |
Modified nucleoside, nucleotide, and nucleic acid compositions
|
CA2858247A1
(en)
|
2011-12-16 |
2013-06-20 |
Novartis Ag |
Aerosolization apparatus for inhalation profile-independent drug delivery
|
EP2791169B1
(en)
|
2011-12-16 |
2017-07-19 |
Synthon Biopharmaceuticals B.V. |
Compounds and methods for treating inflammatory diseases
|
WO2013090601A2
(en)
|
2011-12-16 |
2013-06-20 |
Massachusetts Institute Of Technology |
Compact nanoparticles for biological applications
|
KR20140103168A
(en)
|
2011-12-16 |
2014-08-25 |
알러간, 인코포레이티드 |
Ophthalmic compositions comprising polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymers
|
ES2627856T3
(en)
|
2011-12-19 |
2017-07-31 |
The University Of Sydney |
Peptide Hydrogel Composite
|
US9241829B2
(en)
|
2011-12-20 |
2016-01-26 |
Abbott Medical Optics Inc. |
Implantable intraocular drug delivery apparatus, system and method
|
WO2013096812A1
(en)
|
2011-12-23 |
2013-06-27 |
Genentech, Inc. |
Articles of manufacture and methods for co-administration of antibodies
|
WO2013101908A1
(en)
|
2011-12-27 |
2013-07-04 |
Massachusetts Institute Of Technology |
Microneedle devices and uses thereof
|
US10596246B2
(en)
|
2011-12-29 |
2020-03-24 |
Glaxosmithkline Biological Sa |
Adjuvanted combinations of meningococcal factor H binding proteins
|
SI3421601T1
(en)
|
2011-12-30 |
2020-03-31 |
Cellscript, Llc |
Making and using in vitro-synthesized ssrna for introducing into mammalian cells to induce a biological or biochemical effect
|
WO2013103659A1
(en)
|
2012-01-04 |
2013-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Stabilizing rna by incorporating chain-terminating nucleosides at the 3'-terminus
|
EP2800564B1
(en)
|
2012-01-06 |
2020-05-06 |
NeuroBo Pharmaceuticals, Inc. |
Compound for use in methods of reducing risk of cardiovascular disease
|
WO2013106072A1
(en)
|
2012-01-10 |
2013-07-18 |
Sorbent Therapeutics, Inc. |
Compositions comprising crosslinked cation-binding polymers and uses thereof
|
WO2013106073A1
(en)
|
2012-01-10 |
2013-07-18 |
Sorbent Therapeutics, Inc. |
Compositions comprising crosslinked cation-binding polymers and uses thereof
|
WO2013106086A1
(en)
|
2012-01-10 |
2013-07-18 |
Sorbent Therapeutics, Inc. |
Compositions comprising crosslinked cation-binding polymers and uses thereof
|
BR112014017242A8
(en)
|
2012-01-12 |
2017-07-04 |
Stc Unm |
immunogenic hpv l2-containing vlps and related compositions and methods
|
WO2013105101A1
(en)
|
2012-01-13 |
2013-07-18 |
Department Of Biotechnology |
Solid lipid nanoparticles entrapping hydrophilic/ amphiphilic drug and a process for preparing the same
|
US9879254B2
(en)
|
2012-01-18 |
2018-01-30 |
The General Hosptial Corporation |
Targeting RNAs to microvesicles
|
AU2013212068B2
(en)
|
2012-01-26 |
2018-02-15 |
Life Technologies Corporation |
Methods for increasing the infectivity of viruses
|
WO2013112778A1
(en)
|
2012-01-26 |
2013-08-01 |
Life Technologies Corporation |
Methods for increasing the infectivity of viruses
|
WO2013113326A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
WO2013113325A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Negatively charged nucleic acid comprising complexes for immunostimulation
|
EP2623121A1
(en)
|
2012-01-31 |
2013-08-07 |
Bayer Innovation GmbH |
Pharmaceutical composition comprising a polymeric carrier cargo complex and an antigen
|
WO2013116126A1
(en)
|
2012-02-01 |
2013-08-08 |
Merck Sharp & Dohme Corp. |
Novel low molecular weight, biodegradable cationic lipids for oligonucleotide delivery
|
WO2013116656A1
(en)
|
2012-02-03 |
2013-08-08 |
Emory University |
Immunostimulatory compositions, particles, and uses related thereto
|
CA2863044A1
(en)
|
2012-02-03 |
2013-08-08 |
Commonwealth Scientific And Industrial Research Organisation |
Branched polymers
|
WO2013119602A1
(en)
|
2012-02-06 |
2013-08-15 |
President And Fellows Of Harvard College |
Arrdc1-mediated microvesicles (armms) and uses thereof
|
US9700639B2
(en)
|
2012-02-07 |
2017-07-11 |
Aura Biosciences, Inc. |
Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells
|
US10568974B2
(en)
|
2012-02-07 |
2020-02-25 |
Exemplar Genetics Llc |
Animal models of atherosclerosis
|
JP6170074B2
(en)
|
2012-02-09 |
2017-07-26 |
ライフ テクノロジーズ コーポレーション |
Hydrophilic polymer particles and method for producing the same
|
JP2015513788A
(en)
|
2012-02-10 |
2015-05-14 |
イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company |
Production, purification and use of advanced X diblock copolymers
|
WO2013120497A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
|
MX357202B
(en)
|
2012-02-16 |
2018-06-28 |
Vlp Therapeutics Llc |
Virus like particle composition.
|
US20150111955A1
(en)
|
2012-02-17 |
2015-04-23 |
The Children's Hospital Of Philadelphia |
Aav vector compositions and methods for gene transfer to cells, organs and tissues
|
JP6356614B2
(en)
|
2012-02-17 |
2018-07-11 |
ユニバーシティ・オブ・ジョージア・リサーチ・ファウンデイション・インコーポレイテッド |
Nanoparticles for mitochondrial transport of drugs
|
US10398905B2
(en)
|
2012-02-19 |
2019-09-03 |
Nvigen, Inc. |
Uses of porous nanostructure in delivery
|
WO2013124867A1
(en)
|
2012-02-21 |
2013-08-29 |
Amrita Vishwa Vidyapeetham University |
Polymer - polymer or polymer - protein core - shell nano medicine loaded with multiple drug molecules
|
US20140037573A1
(en)
|
2012-02-22 |
2014-02-06 |
Cerulean Pharma Inc. |
Conjugates, particles, compositions, and related methods
|
US20130243867A1
(en)
|
2012-02-23 |
2013-09-19 |
University Of South Florida (A Florida Non-Profit Corporation) |
Micelle compositions and methods for their use
|
KR102384791B1
(en)
|
2012-02-24 |
2022-04-08 |
아뷰터스 바이오파마 코포레이션 |
Trialkyl cationic lipids and methods of use thereof
|
WO2013130535A1
(en)
|
2012-02-27 |
2013-09-06 |
Newgen Biopharma Corporation |
Topical delivery of hormonal and non hormonal nano formulations, methods of making and using the same
|
WO2013128027A1
(en)
|
2012-03-01 |
2013-09-06 |
Amgen Research (Munich) Gmbh |
Long life polypeptide binding molecules
|
US20150094259A1
(en)
|
2012-03-13 |
2015-04-02 |
University Of Kwazulu-Natal |
Transdermal Delivery Devices
|
US10322089B2
(en)
|
2012-03-14 |
2019-06-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Nanoparticles, nanoparticle delivery methods, and systems of delivery
|
AU2013232297B2
(en)
|
2012-03-16 |
2016-01-14 |
The Johns Hopkins University |
Controlled release formulations for the delivery of HIF-1 inhibitors
|
WO2013138346A1
(en)
|
2012-03-16 |
2013-09-19 |
The Johns Hopkins University |
Non-linear multiblock copolymer-drug conjugates for the delivery of active agents
|
NZ631034A
(en)
|
2012-03-16 |
2016-06-24 |
Merck Patent Gmbh |
Targeting aminoacid lipids
|
WO2013142349A1
(en)
|
2012-03-23 |
2013-09-26 |
University Of Chicago |
Compositions and methods related to staphylococcal sbi
|
US9610346B2
(en)
|
2012-03-23 |
2017-04-04 |
International Aids Vaccine Initiative |
Recombinant viral vectors
|
WO2013143555A1
(en)
|
2012-03-26 |
2013-10-03 |
Biontech Ag |
Rna formulation for immunotherapy
|
EP2830991A1
(en)
|
2012-03-26 |
2015-02-04 |
President and Fellows of Harvard College |
Lipid-coated nucleic acid nanostructures of defined shape
|
SG11201405542UA
(en)
|
2012-03-27 |
2014-10-30 |
Curevac Gmbh |
Artificial nucleic acid molecules
|
WO2013148541A1
(en)
|
2012-03-27 |
2013-10-03 |
Merck Sharp & Dohme Corp. |
DIETHER BASED BIODEGRADABLE CATIONIC LIPIDS FOR siRNA DELIVERY
|
SG11201405545XA
(en)
|
2012-03-27 |
2014-11-27 |
Curevac Gmbh |
Artificial nucleic acid molecules comprising a 5'top utr
|
RU2658490C2
(en)
|
2012-03-27 |
2018-06-21 |
Кьюрвак Аг |
Artificial nucleic acid molecules for improved protein or peptide expression
|
JP6211054B2
(en)
|
2012-03-29 |
2017-10-11 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
Lipid-induced neutral nanoparticles
|
US9878056B2
(en)
|
2012-04-02 |
2018-01-30 |
Modernatx, Inc. |
Modified polynucleotides for the production of cosmetic proteins and peptides
|
EP2833892A4
(en)
|
2012-04-02 |
2016-07-20 |
Moderna Therapeutics Inc |
Modified polynucleotides for the production of oncology-related proteins and peptides
|
WO2013151666A2
(en)
*
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of biologics and proteins associated with human disease
|
US20150064115A1
(en)
|
2012-04-05 |
2015-03-05 |
University Of Florida Research Foundation, Inc. |
Neurophilic nanoparticles
|
US9107904B2
(en)
|
2012-04-05 |
2015-08-18 |
Massachusetts Institute Of Technology |
Immunostimulatory compositions and methods of use thereof
|
WO2013152351A2
(en)
|
2012-04-06 |
2013-10-10 |
The Trustees Of Columbia University In The City Of New York |
Fusion polypeptides and methods of use thereof
|
EP2836200B1
(en)
|
2012-04-08 |
2020-07-15 |
Urogen Pharma Ltd. |
Reverse thermal hydrogel preparations for use in the treatment of disorders of the urothelium
|
JP5927338B2
(en)
|
2012-04-11 |
2016-06-01 |
インテザイン テクノロジーズ, インコーポレイテッド |
Block copolymer for stable micelles
|
WO2013155493A1
(en)
|
2012-04-12 |
2013-10-17 |
Yale University |
Methods of treating inflammatory and autoimmune diseases and disorders
|
WO2013155513A1
(en)
|
2012-04-13 |
2013-10-17 |
President And Fellows Of Harvard College |
Devices and methods for in vitro aerosol delivery
|
WO2013154766A1
(en)
|
2012-04-13 |
2013-10-17 |
New York University |
Microrna control of ldl receptor pathway
|
AU2012377385A1
(en)
|
2012-04-18 |
2014-01-23 |
Arrowhead Research Corporation |
Poly(acrylate) polymers for in vivo nucleic acid delivery
|
JP6232416B2
(en)
|
2012-04-19 |
2017-11-15 |
サーナ・セラピューティクス・インコーポレイテッドSirna Therapeutics,Inc. |
Novel diester and triester-based low molecular weight, biodegradable cationic lipids for oligonucleotide delivery
|
EP2841056A4
(en)
|
2012-04-23 |
2015-09-16 |
Massachusetts Inst Technology |
Stable layer-by-layer coated particles
|
JP6322189B2
(en)
|
2012-04-25 |
2018-05-09 |
レグルス セラピューティクス インコーポレイテッド |
MicroRNA compounds and methods for modulating MIR-21 activity
|
EP4008355A1
(en)
|
2012-05-03 |
2022-06-08 |
Kala Pharmaceuticals, Inc. |
Pharmaceutical nanoparticles showing improved mucosal transport
|
EP2849728A1
(en)
|
2012-05-04 |
2015-03-25 |
The Johns Hopkins University |
Lipid-based drug carriers for rapid penetration through mucus linings
|
US20150087671A1
(en)
|
2012-05-16 |
2015-03-26 |
Micell Technologies, Inc. |
Low burst sustained release lipophilic and biologic agent compositions
|
US9399672B2
(en)
|
2012-05-17 |
2016-07-26 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Hepatitis C virus neutralizing antibody
|
WO2013173693A1
(en)
|
2012-05-18 |
2013-11-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Nanoparticles with enhanced entry into cancer cells
|
BR112014029247A2
(en)
|
2012-05-23 |
2017-06-27 |
Univ Ohio State |
lipid nanoparticle, pharmaceutical composition, method for making a lipid nanoparticle, product, method of treating a disorder, and delivery system
|
WO2013174409A1
(en)
|
2012-05-25 |
2013-11-28 |
Curevac Gmbh |
Reversible immobilization and/or controlled release of nucleic acid containing nanoparticles by (biodegradable) polymer coatings
|
CA2874453C
(en)
|
2012-06-06 |
2021-05-18 |
Loma Vista Medical, Inc. |
Inflatable medical devices
|
HUE056014T2
(en)
|
2012-06-08 |
2022-01-28 |
Nitto Denko Corp |
Lipids for therapeutic agent delivery formulations
|
EA201492055A1
(en)
|
2012-06-08 |
2015-11-30 |
Шир Хьюман Дженетик Терапис, Инк. |
INHALATIVE DELIVERY OF mRNA IN TIGHTNESS CELL TARGETS
|
DK2858677T3
(en)
|
2012-06-08 |
2020-08-31 |
Ethris Gmbh |
PULMONARY DELIVERY OF MESSENGER RNA
|
US9993439B2
(en)
|
2012-06-20 |
2018-06-12 |
University Of Waterloo |
Mucoadhesive nanoparticle delivery system
|
WO2014014613A2
(en)
|
2012-06-20 |
2014-01-23 |
President And Fellows Of Harvard College |
Self-assembling peptides, peptide nanostructures and uses thereof
|
US9803010B2
(en)
|
2012-06-27 |
2017-10-31 |
Merck Sharp & Dohme Corp. |
Crystalline anti-human IL-23p19 antibodies
|
TW201408625A
(en)
|
2012-07-06 |
2014-03-01 |
Kyowa Hakko Kirin Co Ltd |
Cationic lipid
|
US9956291B2
(en)
|
2012-07-10 |
2018-05-01 |
Shaker A. Mousa |
Nanoformulation and methods of use of thyroid receptor beta1 agonists for liver targeting
|
WO2014014890A1
(en)
|
2012-07-16 |
2014-01-23 |
Nanoderm Sciences, Inc. |
Targeted therapeutic nanoparticles
|
EP2687251A1
(en)
|
2012-07-17 |
2014-01-22 |
Sanofi-Aventis Deutschland GmbH |
Drug delivery device
|
EP2687252A1
(en)
|
2012-07-17 |
2014-01-22 |
Sanofi-Aventis Deutschland GmbH |
Drug delivery device
|
CN112587671A
(en)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
Targeted immunotherapy for cancer
|
WO2014015334A1
(en)
|
2012-07-20 |
2014-01-23 |
Brown University |
System and methods for nanostructure protected delivery of treatment agent and selective release thereof
|
KR20160073936A
(en)
|
2012-07-24 |
2016-06-27 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
Self-assembly of nucleic acid nanostructures
|
GB201213624D0
(en)
|
2012-07-27 |
2012-09-12 |
Univ Ulster The |
Method and system for production of conjugated nanoparticles
|
WO2014015422A1
(en)
|
2012-07-27 |
2014-01-30 |
Ontario Institute For Cancer Research |
Cellulose-based nanoparticles for drug delivery
|
WO2014024193A1
(en)
|
2012-08-07 |
2014-02-13 |
Prodel Pharma Ltd. |
Compositions and methods for rapid transmucosal delivery of pharmaceutical ingredients
|
US9931418B2
(en)
|
2012-08-07 |
2018-04-03 |
Northeastern University |
Compositions for the delivery of RNA and drugs into cells
|
JP2015533522A
(en)
|
2012-08-08 |
2015-11-26 |
プレサージュ バイオサイエンシズ,インコーポレイテッド |
Extrusion methods and devices for drug delivery
|
CN104582747B
(en)
|
2012-08-08 |
2016-12-21 |
南洋理工大学 |
For manufacturing the method for the hydrogel fines with living cells and for manufacturing the compositions of tissue engineering bracket
|
CN104736181A
(en)
|
2012-08-10 |
2015-06-24 |
北德克萨斯大学健康科学中心 |
Drug delivery vehicle comprising conjugates between targeting polyamino acids and fatty acids
|
WO2014027006A1
(en)
|
2012-08-13 |
2014-02-20 |
Edko Pazarlama Tanitim Ticaret Limited Sirketi |
Bioadhesive formulations for use in drug delivery
|
CA2884870C
(en)
|
2012-08-13 |
2022-03-29 |
Massachusetts Institute Of Technology |
Amine-containing lipidoids and uses thereof
|
US9827321B2
(en)
|
2012-08-14 |
2017-11-28 |
The Trustees Of The University Of Pennsylvania |
Stabilizing shear-thinning hydrogels
|
US9775804B2
(en)
|
2012-08-14 |
2017-10-03 |
Aaron Froese |
Internal structured self assembling liposomes
|
CA2882248A1
(en)
|
2012-08-15 |
2014-02-20 |
The University Of Chicago |
Exosome-based therapeutics against neurodegenerative disorders
|
WO2014039185A1
(en)
|
2012-09-05 |
2014-03-13 |
Creighton University |
Polymeric nanoparticles in a thermosensitive gel for coital-independent vaginal prophylaxis of hiv
|
US8703197B2
(en)
|
2012-09-13 |
2014-04-22 |
International Business Machines Corporation |
Branched polyamines for delivery of biologically active materials
|
MX356097B
(en)
|
2012-09-17 |
2018-05-14 |
Pfizer Inc Star |
Process for preparing therapeutic nanoparticles.
|
WO2014047649A1
(en)
|
2012-09-24 |
2014-03-27 |
The Regents Of The University Of California |
Methods for arranging and packing nucleic acids for unusual resistance to nucleases and targeted delivery for gene therapy
|
CA2925687A1
(en)
|
2012-09-27 |
2014-04-03 |
The University Of North Carolina At Chapel Hill |
Lipid coated nanoparticles containing agents having low aqueous and lipid solubilities and methods thereof
|
WO2014053879A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
WO2014053880A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
CN104812372A
(en)
|
2012-10-04 |
2015-07-29 |
约翰内斯堡金山大学 |
Liposomal medicine delivery system
|
WO2014053882A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
WO2014053881A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
EP2716655A1
(en)
|
2012-10-04 |
2014-04-09 |
Institut Pasteur |
Neutralizing antibodies directed against Hepatitis C virus ectodomain glycoprotein E2
|
US20140100178A1
(en)
|
2012-10-04 |
2014-04-10 |
Aslam Ansari |
Composition and methods for site-specific drug delivery to treat malaria and other liver diseases
|
EP2716689A1
(en)
|
2012-10-05 |
2014-04-09 |
National University of Ireland, Galway |
Polymer comprising a plurality of branches having at least one disulfide group and/or at least one vinyl group
|
WO2014064534A2
(en)
|
2012-10-05 |
2014-05-01 |
Chrontech Pharma Ab |
Injection needle, device, immunogenic compositions and method of use
|
US9931410B2
(en)
|
2012-10-09 |
2018-04-03 |
The Brigham And Women's Hospital, Inc. |
Nanoparticles for targeted delivery of multiple therapeutic agents and methods of use
|
US20140106260A1
(en)
|
2012-10-11 |
2014-04-17 |
The Trustees Of The University Of Pennsylvania |
Core-shell nanoparticulate compositions and methods
|
CA2887727A1
(en)
|
2012-10-16 |
2014-04-24 |
Endocyte, Inc. |
Drug delivery conjugates containing unnatural amino acids and methods for using
|
EA035012B1
(en)
|
2012-10-18 |
2020-04-17 |
Рокфеллер Юниверсити (Дзе) |
Broadly-neutralizing anti-hiv antibodies
|
CN104918639B
(en)
|
2012-10-22 |
2018-01-26 |
萨拜格Rfa公司 |
System for being delivered to therapeutic agent in living cells and nucleus
|
CA2889608A1
(en)
|
2012-10-26 |
2014-05-01 |
Nlife Therapeutics, S.L. |
Compositions and methods for selective delivery of oligonucleotide molecules to cell types
|
WO2014066898A1
(en)
|
2012-10-26 |
2014-05-01 |
The Johns Hopkins University |
A layer-by-layer approach to co-deliver dna and sirna via aunps: a potential platform for modifying release kinetics
|
WO2014066912A1
(en)
|
2012-10-26 |
2014-05-01 |
Vanderbilt University |
Polymeric nanoparticles
|
EP2912180A1
(en)
|
2012-10-29 |
2015-09-02 |
Technische Universität Dortmund |
T7 rna polymerase variants and methods of using the same
|
US20140120091A1
(en)
|
2012-10-31 |
2014-05-01 |
University Of Washington Through Its Center For Commercialization |
Fusion proteins for therapy of autoimmune and cardiovascular disease
|
KR102596302B1
(en)
|
2012-11-01 |
2023-11-01 |
팩터 바이오사이언스 인크. |
Methods and products for expressing proteins in cells
|
WO2014071072A2
(en)
|
2012-11-02 |
2014-05-08 |
Pungente Michael D |
Novel cationic carotenoid-based lipids for cellular nucleic acid uptake
|
US10017767B2
(en)
|
2012-11-05 |
2018-07-10 |
Fondazione Centro San Raffaele |
Targets in multiple myeloma and other disorders
|
JP6267218B2
(en)
|
2012-11-06 |
2018-01-24 |
ロチャル インダストリーズ,エルエルシー |
Delivery of biologically active agents using volatile and hydrophobic solvents
|
WO2014074597A1
(en)
|
2012-11-06 |
2014-05-15 |
President And Fellows Of Harvard College |
Compositions and methods relating to complex nucleic acid nanostructures
|
EP2916873B1
(en)
|
2012-11-07 |
2017-07-26 |
Council of Scientific & Industrial Research |
Nanocomplex containing amphipathic peptide useful for efficient transfection of biomolecules
|
EP2916874B1
(en)
|
2012-11-07 |
2018-08-29 |
Council of Scientific and Industrial Research |
Nanocomplex containing cationic peptide for biomolecule delivery
|
EP3489258A1
(en)
|
2012-11-08 |
2019-05-29 |
Eleven Biotherapeutics, Inc. |
Il-6 antagonists and uses thereof
|
TW201428101A
(en)
|
2012-11-08 |
2014-07-16 |
Inviragen Inc |
Compositions, methods and uses for dengue virus serotype-4 constructs
|
BR112015010318A2
(en)
|
2012-11-08 |
2017-08-22 |
Albumedix As |
ALBUMIN VARIANTS
|
CN104884049A
(en)
|
2012-11-08 |
2015-09-02 |
克莱尔塞德生物医学股份有限公司 |
Methods and devices for the treatment of ocular diseases in human subjects
|
EP2916853B1
(en)
|
2012-11-09 |
2020-05-06 |
Velin-Pharma A/S |
Compositions for pulmonary delivery
|
US9200119B2
(en)
|
2012-11-09 |
2015-12-01 |
Momentive Performance Materials Inc. |
Silicon-containing zwitterionic linear copolymer composition
|
WO2014071963A1
(en)
|
2012-11-09 |
2014-05-15 |
Biontech Ag |
Method for cellular rna expression
|
AU2013343864B2
(en)
|
2012-11-09 |
2019-04-04 |
BioNTech SE |
Method for cellular RNA expression
|
EP2916862B1
(en)
|
2012-11-12 |
2020-01-08 |
GenVec, Inc. |
Malaria antigens and methods of use
|
EP2916835A4
(en)
|
2012-11-12 |
2016-07-27 |
Redwood Bioscience Inc |
Compounds and methods for producing a conjugate
|
GB201220354D0
(en)
|
2012-11-12 |
2012-12-26 |
Medpharm Ltd |
Dermal compositions
|
WO2014078399A1
(en)
|
2012-11-13 |
2014-05-22 |
Baylor College Of Medicine |
Multi-arm biodegradable polymers for nucleic acid delivery
|
WO2014078636A1
(en)
|
2012-11-16 |
2014-05-22 |
President And Fellows Of Harvard College |
Nucleic acid hydrogel self-assembly
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
WO2014076709A1
(en)
|
2012-11-19 |
2014-05-22 |
Technion Research And Development Foundation Ltd. |
Liposomes for in-vivo delivery
|
EP2732825B1
(en)
|
2012-11-19 |
2015-07-01 |
Invivogen |
Conjugates of a TLR7 and/or TLR8 agonist and a TLR2 agonist
|
WO2014081849A1
(en)
|
2012-11-20 |
2014-05-30 |
Phasebio Pharmaceuticals, Inc. |
Formulations of active agents for sustained release
|
WO2014081299A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Activatable liposomes
|
US10927139B2
(en)
|
2012-11-22 |
2021-02-23 |
Tagworks Pharmaceuticals B.V. |
Chemically cleavable group
|
WO2014081300A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Channel protein activatable liposomes
|
JP6144355B2
(en)
|
2012-11-26 |
2017-06-07 |
モデルナティエックス インコーポレイテッドModernaTX,Inc. |
Chemically modified mRNA
|
WO2014089486A1
(en)
|
2012-12-07 |
2014-06-12 |
Shire Human Genetic Therapies, Inc. |
Lipidic nanoparticles for mrna delivering
|
WO2014108515A1
(en)
|
2013-01-10 |
2014-07-17 |
Novartis Ag |
Influenza virus immunogenic compositions and uses thereof
|
JP2016504050A
(en)
|
2013-01-17 |
2016-02-12 |
モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. |
Signal sensor polynucleotide for modification of cell phenotype
|
DK2958588T3
(en)
|
2013-02-22 |
2017-11-20 |
Curevac Ag |
Combination of vaccination and inhibition of PD-1 pathway
|
WO2014152940A1
(en)
|
2013-03-14 |
2014-09-25 |
Shire Human Genetic Therapies, Inc. |
Mrna therapeutic compositions and use to treat diseases and disorders
|
AU2014239184B2
(en)
|
2013-03-14 |
2018-11-08 |
Translate Bio, Inc. |
Methods and compositions for delivering mRNA coded antibodies
|
EA201591281A1
(en)
|
2013-03-14 |
2016-02-29 |
Шир Хьюман Дженетик Терапис, Инк. |
RIBONUCLEIC ACIDS WITH 4'-THIOMODIFIED NUCLEOTIDES AND RELATED METHODS
|
EP2971013B1
(en)
|
2013-03-15 |
2020-08-19 |
The University Of British Columbia |
Lipid nanoparticles for transfection and related methods
|
EP3757570B1
(en)
|
2013-03-15 |
2023-10-11 |
Translate Bio, Inc. |
Synergistic enhancement of the delivery of nucleic acids via blended formulations
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
HUE042072T2
(en)
|
2013-03-15 |
2019-06-28 |
Glaxosmithkline Biologicals Sa |
Rna purification methods
|
US10246708B2
(en)
|
2013-05-06 |
2019-04-02 |
Alnylam Pharmaceuticals, Inc. |
Dosages and methods for delivering lipid formulated nucleic acid molecules
|
US9895443B2
(en)
|
2013-06-26 |
2018-02-20 |
Massachusetts Institute Of Technology |
Multi-tailed lipids and uses thereof
|
CN110974981A
(en)
|
2013-07-23 |
2020-04-10 |
野草莓树生物制药公司 |
Compositions and methods for delivering messenger RNA
|
WO2015023461A2
(en)
|
2013-08-06 |
2015-02-19 |
The Trustees Of The University Of Pennsylvania |
Influenza nucleic acid molecules and vaccines made therefrom
|
AU2014310935B2
(en)
|
2013-08-21 |
2019-11-21 |
CureVac SE |
Combination vaccine
|
BR112016003361A2
(en)
|
2013-08-21 |
2017-11-21 |
Curevac Ag |
respiratory syncytial virus vaccine (rsv)
|
US10323076B2
(en)
|
2013-10-03 |
2019-06-18 |
Modernatx, Inc. |
Polynucleotides encoding low density lipoprotein receptor
|
EA201690576A1
(en)
|
2013-10-22 |
2016-10-31 |
Шир Хьюман Дженетик Терапис, Инк. |
LIPID COMPOSITIONS FOR DELIVERY OF MATRIX RNA
|
RS58337B1
(en)
|
2014-03-24 |
2019-03-29 |
Translate Bio Inc |
Mrna therapy for the treatment of ocular diseases
|
WO2015154002A1
(en)
|
2014-04-04 |
2015-10-08 |
Ohio State Innovation Foundation |
Oligonucleotide lipid nanoparticle compositions, methods of making and methods of using the same
|
CA2946392A1
(en)
|
2014-04-25 |
2015-10-29 |
James M. Wilson |
Ldlr variants and their use in compositions for reducing cholesterol levels
|
ES2834556T3
(en)
|
2014-06-25 |
2021-06-17 |
Acuitas Therapeutics Inc |
Novel lipid and lipid nanoparticle formulations for nucleic acid delivery
|
JP6782171B2
(en)
|
2014-07-02 |
2020-11-11 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
Encapsulation of messenger RNA
|
EP3164379A1
(en)
|
2014-07-02 |
2017-05-10 |
Massachusetts Institute of Technology |
Polyamine-fatty acid derived lipidoids and uses thereof
|
CN104644555A
(en)
|
2014-11-18 |
2015-05-27 |
中国科学院过程工程研究所 |
Long-circulating liposome capable of avoiding accelerated blood clearance (ABC) phenomenon, and preparation method and application thereof
|
JP2018509387A
(en)
|
2015-01-21 |
2018-04-05 |
フェーズアールエックス インコーポレイテッド |
Methods, compositions, and systems for delivering therapeutic and diagnostic agents to cells
|
EP3247363A4
(en)
|
2015-01-21 |
2018-10-03 |
Moderna Therapeutics, Inc. |
Lipid nanoparticle compositions
|
WO2016164762A1
(en)
*
|
2015-04-08 |
2016-10-13 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor egf-a and intracellular domain mutants and methods of using the same
|
AU2016253972B2
(en)
|
2015-04-27 |
2020-01-02 |
Acuitas Therapeutics Inc. |
Nucleoside-modified RNA for inducing an adaptive immune response
|
US20190119357A1
(en)
|
2015-07-23 |
2019-04-25 |
Modernatx, Inc. |
Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
|
US11564893B2
(en)
|
2015-08-17 |
2023-01-31 |
Modernatx, Inc. |
Methods for preparing particles and related compositions
|
HRP20220156T1
(en)
|
2015-09-17 |
2022-04-15 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of therapeutic agents
|
JP7080172B2
(en)
|
2015-12-10 |
2022-06-03 |
モデルナティエックス インコーポレイテッド |
Compositions and Methods for Delivery of Therapeutic Agents
|
DK3394030T3
(en)
|
2015-12-22 |
2022-03-28 |
Modernatx Inc |
COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR RELEASE OF FUNDS
|
EP3405579A1
(en)
|
2016-01-22 |
2018-11-28 |
Modernatx, Inc. |
Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
|
US20190167811A1
(en)
|
2016-04-13 |
2019-06-06 |
Modernatx, Inc. |
Lipid compositions and their uses for intratumoral polynucleotide delivery
|
WO2017192470A1
(en)
|
2016-05-03 |
2017-11-09 |
Merck Sharp & Dohme Corp. |
Combination therapy of anti-il-10 antibody and compositions comprising lipid nanoparticles and tlr9 agonist cpg oligonucleotides
|
MA45050A
(en)
|
2016-05-18 |
2019-03-27 |
Modernatx Inc |
LIPOPROTEIN LIPASE CODING POLYNUCLEOTIDES FOR THE TREATMENT OF HYPERLIPIDEMIA
|
WO2017201317A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Polyribonucleotides containing reduced uracil content and uses thereof
|
SI3458083T1
(en)
|
2016-05-18 |
2023-03-31 |
Modernatx, Inc. |
Polynucleotides encoding interleukin-12 (il12) and uses thereof
|
MA45053A
(en)
|
2016-05-18 |
2019-03-27 |
Modernatx Inc |
POLYNUCLEOTIDES CODING FOR A CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR FOR THE TREATMENT OF CYSTIC FIBROSIS
|
IL263079B2
(en)
|
2016-05-18 |
2024-05-01 |
Modernatx Inc |
Polynucleotides encoding relaxin
|
AU2017266929B2
(en)
|
2016-05-18 |
2023-05-11 |
Modernatx, Inc. |
Combinations of mRNAs encoding immune modulating polypeptides and uses thereof
|
US20200069599A1
(en)
|
2016-06-14 |
2020-03-05 |
Modernatx, Inc. |
Stabilized formulations of lipid nanoparticles
|
AU2018234828A1
(en)
|
2017-03-15 |
2019-09-19 |
Modernatx, Inc. |
Lipid nanoparticle formulation
|
KR20190132405A
(en)
|
2017-03-15 |
2019-11-27 |
모더나티엑스, 인크. |
Compounds and Compositions for Intracellular Delivery of Therapeutic Agents
|