RO117849B1 - Derivati de chinazolina, procedeu de preparare a acestora, compozitie farmaceutica si metoda de producere a unui efect antiproliferativ - Google Patents

Derivati de chinazolina, procedeu de preparare a acestora, compozitie farmaceutica si metoda de producere a unui efect antiproliferativ Download PDF

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Publication number
RO117849B1
RO117849B1 RO97-01978A RO9701978A RO117849B1 RO 117849 B1 RO117849 B1 RO 117849B1 RO 9701978 A RO9701978 A RO 9701978A RO 117849 B1 RO117849 B1 RO 117849B1
Authority
RO
Romania
Prior art keywords
quinazoline
chloro
pharmaceutically acceptable
alkoxy
methoxy
Prior art date
Application number
RO97-01978A
Other languages
English (en)
Romanian (ro)
Inventor
Keith Hopkinson Gibson
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10773597&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RO117849(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of RO117849B1 publication Critical patent/RO117849B1/ro

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
RO97-01978A 1995-04-27 1996-04-23 Derivati de chinazolina, procedeu de preparare a acestora, compozitie farmaceutica si metoda de producere a unui efect antiproliferativ RO117849B1 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9508538.7A GB9508538D0 (en) 1995-04-27 1995-04-27 Quinazoline derivatives
PCT/GB1996/000961 WO1996033980A1 (en) 1995-04-27 1996-04-23 Quinazoline derivatives

Publications (1)

Publication Number Publication Date
RO117849B1 true RO117849B1 (ro) 2002-08-30

Family

ID=10773597

Family Applications (1)

Application Number Title Priority Date Filing Date
RO97-01978A RO117849B1 (ro) 1995-04-27 1996-04-23 Derivati de chinazolina, procedeu de preparare a acestora, compozitie farmaceutica si metoda de producere a unui efect antiproliferativ

Country Status (38)

Country Link
US (1) US5770599A (enExample)
EP (1) EP0823900B1 (enExample)
JP (1) JP3040486B2 (enExample)
KR (1) KR100296656B1 (enExample)
CN (1) CN1100046C (enExample)
AR (1) AR003944A1 (enExample)
AT (1) ATE198329T1 (enExample)
AU (1) AU699163B2 (enExample)
BG (1) BG62730B1 (enExample)
BR (1) BRPI9608082B8 (enExample)
CA (1) CA2215732C (enExample)
CZ (1) CZ288489B6 (enExample)
DE (2) DE122009000076I1 (enExample)
DK (1) DK0823900T3 (enExample)
EE (1) EE03482B1 (enExample)
EG (1) EG24134A (enExample)
ES (1) ES2153098T3 (enExample)
FR (1) FR09C0065I2 (enExample)
GB (1) GB9508538D0 (enExample)
GR (1) GR3035211T3 (enExample)
HR (1) HRP960204B1 (enExample)
HU (1) HU223313B1 (enExample)
IL (1) IL118045A (enExample)
LU (1) LU91631I2 (enExample)
MY (1) MY114425A (enExample)
NL (1) NL300429I1 (enExample)
NO (2) NO309472B1 (enExample)
NZ (1) NZ305444A (enExample)
PL (1) PL189182B1 (enExample)
PT (1) PT823900E (enExample)
RO (1) RO117849B1 (enExample)
RU (1) RU2153495C2 (enExample)
SI (1) SI0823900T1 (enExample)
SK (1) SK282236B6 (enExample)
TW (1) TW436486B (enExample)
UA (1) UA52602C2 (enExample)
WO (1) WO1996033980A1 (enExample)
ZA (1) ZA963358B (enExample)

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