MX9709867A - Derivados de pirimidina condensados con un anillo heterociclico, composiciones que contienen los mismos, y uso de los mismos. - Google Patents

Derivados de pirimidina condensados con un anillo heterociclico, composiciones que contienen los mismos, y uso de los mismos.

Info

Publication number
MX9709867A
MX9709867A MX9709867A MX9709867A MX9709867A MX 9709867 A MX9709867 A MX 9709867A MX 9709867 A MX9709867 A MX 9709867A MX 9709867 A MX9709867 A MX 9709867A MX 9709867 A MX9709867 A MX 9709867A
Authority
MX
Mexico
Prior art keywords
heterocyclic ring
pyrimidine derivatives
fused pyrimidine
formula
fused
Prior art date
Application number
MX9709867A
Other languages
English (en)
Inventor
Lee Daniel Arnold
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX9709867A publication Critical patent/MX9709867A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom

Abstract

Un compuesto de formula (Ver Formula), y los estereoisomeros, sales farmacéuticamente aceptables y profármacos del mismo, en la que Z e Y son como se han definido anteriormente; los compuestos de Formula I son utiles en la preparacion de composiciones para el tratamiento de enfermedades hiperproliferativas, tales como cánceres y otros trastornos en mamíferos.
MX9709867A 1995-06-07 1995-06-07 Derivados de pirimidina condensados con un anillo heterociclico, composiciones que contienen los mismos, y uso de los mismos. MX9709867A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1995/007881 WO1996040142A1 (en) 1995-06-07 1995-06-07 Heterocyclic ring-fused pyrimidine derivatives
HU9601559A HUP9601559A3 (en) 1995-06-07 1996-06-06 Heterocyclic ring-fused pyrimidine derivatives, pharmaceutical compositions containing the same and intermediates

Publications (1)

Publication Number Publication Date
MX9709867A true MX9709867A (es) 1998-03-31

Family

ID=89994036

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9709867A MX9709867A (es) 1995-06-07 1995-06-07 Derivados de pirimidina condensados con un anillo heterociclico, composiciones que contienen los mismos, y uso de los mismos.

Country Status (32)

Country Link
EP (1) EP0831829B1 (es)
JP (1) JP3290666B2 (es)
CN (1) CN1141298A (es)
AP (1) AP637A (es)
AR (1) AR002746A1 (es)
AT (1) ATE247469T1 (es)
AU (1) AU5479196A (es)
BR (1) BR9602695A (es)
CA (1) CA2223081C (es)
CO (1) CO4440628A1 (es)
CZ (1) CZ164196A3 (es)
DE (1) DE69531558T2 (es)
DK (1) DK0831829T3 (es)
ES (1) ES2203642T3 (es)
FI (1) FI974443A (es)
HR (1) HRP960269A2 (es)
HU (1) HUP9601559A3 (es)
IL (1) IL118487A0 (es)
MA (1) MA26409A1 (es)
MX (1) MX9709867A (es)
NO (1) NO962386L (es)
NZ (1) NZ286755A (es)
OA (1) OA10460A (es)
PL (1) PL314641A1 (es)
PT (1) PT831829E (es)
RU (1) RU2136683C1 (es)
SG (1) SG45483A1 (es)
SI (1) SI9600184A (es)
SK (1) SK72996A3 (es)
TR (1) TR199600474A2 (es)
WO (1) WO1996040142A1 (es)
ZA (1) ZA964725B (es)

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CA2223081A1 (en) 1996-12-19
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AR002746A1 (es) 1998-04-29
CN1141298A (zh) 1997-01-29
FI974443A (fi) 1997-12-05
TR199600474A2 (tr) 1996-12-21
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