DK2295441T3 - Bicyklonukleosidoligonukleotidanalog - Google Patents

Bicyklonukleosidoligonukleotidanalog

Info

Publication number
DK2295441T3
DK2295441T3 DK10172971.3T DK10172971T DK2295441T3 DK 2295441 T3 DK2295441 T3 DK 2295441T3 DK 10172971 T DK10172971 T DK 10172971T DK 2295441 T3 DK2295441 T3 DK 2295441T3
Authority
DK
Denmark
Prior art keywords
analogue
bicyclonucleoside
oligonucleotide analog
oligonucleotide
hydrolyzable
Prior art date
Application number
DK10172971.3T
Other languages
English (en)
Inventor
Takeshi Imanishi
Satoshi Obika
Original Assignee
Santaris Pharma As
Exiqon As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12942037&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2295441(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Santaris Pharma As, Exiqon As filed Critical Santaris Pharma As
Application granted granted Critical
Publication of DK2295441T3 publication Critical patent/DK2295441T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK10172971.3T 1997-03-07 1998-03-09 Bicyklonukleosidoligonukleotidanalog DK2295441T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5340997 1997-03-07
EP98905804.5A EP1013661B2 (en) 1997-03-07 1998-03-09 2'-O,4'-C-methylene bicyclonucleosides

Publications (1)

Publication Number Publication Date
DK2295441T3 true DK2295441T3 (da) 2014-07-21

Family

ID=12942037

Family Applications (3)

Application Number Title Priority Date Filing Date
DK98905804.5T DK1013661T4 (da) 1997-03-07 1998-03-09 2'-O,4'-C-methylen bicyklonukleosider
DK10172971.3T DK2295441T3 (da) 1997-03-07 1998-03-09 Bicyklonukleosidoligonukleotidanalog
DK10011863.7T DK2361921T3 (da) 1997-03-07 1998-03-09 Bicyklooligonukleotidanaloger

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK98905804.5T DK1013661T4 (da) 1997-03-07 1998-03-09 2'-O,4'-C-methylen bicyklonukleosider

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK10011863.7T DK2361921T3 (da) 1997-03-07 1998-03-09 Bicyklooligonukleotidanaloger

Country Status (12)

Country Link
US (1) US6268490B1 (da)
EP (3) EP2361921B1 (da)
JP (1) JP3756313B2 (da)
AT (1) ATE541576T2 (da)
AU (1) AU720472B2 (da)
CA (1) CA2283509C (da)
DE (1) DE98905804T1 (da)
DK (3) DK1013661T4 (da)
ES (3) ES2485716T3 (da)
HK (1) HK1154590A1 (da)
PT (2) PT2295441E (da)
WO (1) WO1998039352A1 (da)

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WO1998039352A1 (fr) 1998-09-11
AU720472B2 (en) 2000-06-01
CA2283509A1 (en) 1998-09-11
JP3756313B2 (ja) 2006-03-15

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