US5882330A
(en)
*
|
1984-05-25 |
1999-03-16 |
Lemelson; Jerome H. |
Drugs and methods for treating diseases
|
US5456663A
(en)
*
|
1984-05-25 |
1995-10-10 |
Lemelson; Jerome H. |
Drugs and methods for treating diseases
|
US5925375A
(en)
*
|
1987-05-22 |
1999-07-20 |
The Liposome Company, Inc. |
Therapeutic use of multilamellar liposomal prostaglandin formulations
|
JPH0720857B2
(ja)
*
|
1988-08-11 |
1995-03-08 |
テルモ株式会社 |
リポソームおよびその製法
|
US6132763A
(en)
*
|
1988-10-20 |
2000-10-17 |
Polymasc Pharmaceuticals Plc |
Liposomes
|
GB8824593D0
(en)
*
|
1988-10-20 |
1988-11-23 |
Royal Free Hosp School Med |
Liposomes
|
US5153000A
(en)
*
|
1988-11-22 |
1992-10-06 |
Kao Corporation |
Phosphate, liposome comprising the phosphate as membrane constituent, and cosmetic and liposome preparation comprising the liposome
|
US5013556A
(en)
*
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
US5527528A
(en)
*
|
1989-10-20 |
1996-06-18 |
Sequus Pharmaceuticals, Inc. |
Solid-tumor treatment method
|
US20010051183A1
(en)
*
|
1989-10-20 |
2001-12-13 |
Alza Corporation |
Liposomes with enhanced circulation time and method of treatment
|
US5356633A
(en)
*
|
1989-10-20 |
1994-10-18 |
Liposome Technology, Inc. |
Method of treatment of inflamed tissues
|
US5843473A
(en)
*
|
1989-10-20 |
1998-12-01 |
Sequus Pharmaceuticals, Inc. |
Method of treatment of infected tissues
|
US5620689A
(en)
*
|
1989-10-20 |
1997-04-15 |
Sequus Pharmaceuuticals, Inc. |
Liposomes for treatment of B-cell and T-cell disorders
|
US5776429A
(en)
*
|
1989-12-22 |
1998-07-07 |
Imarx Pharmaceutical Corp. |
Method of preparing gas-filled microspheres using a lyophilized lipids
|
US5705187A
(en)
*
|
1989-12-22 |
1998-01-06 |
Imarx Pharmaceutical Corp. |
Compositions of lipids and stabilizing materials
|
US5656211A
(en)
*
|
1989-12-22 |
1997-08-12 |
Imarx Pharmaceutical Corp. |
Apparatus and method for making gas-filled vesicles of optimal size
|
US5922304A
(en)
|
1989-12-22 |
1999-07-13 |
Imarx Pharmaceutical Corp. |
Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
|
US5733572A
(en)
*
|
1989-12-22 |
1998-03-31 |
Imarx Pharmaceutical Corp. |
Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
|
US5469854A
(en)
*
|
1989-12-22 |
1995-11-28 |
Imarx Pharmaceutical Corp. |
Methods of preparing gas-filled liposomes
|
US5441746A
(en)
*
|
1989-12-22 |
1995-08-15 |
Molecular Bioquest, Inc. |
Electromagnetic wave absorbing, surface modified magnetic particles for use in medical applications, and their method of production
|
US6146657A
(en)
|
1989-12-22 |
2000-11-14 |
Imarx Pharmaceutical Corp. |
Gas-filled lipid spheres for use in diagnostic and therapeutic applications
|
US5305757A
(en)
*
|
1989-12-22 |
1994-04-26 |
Unger Evan C |
Gas filled liposomes and their use as ultrasonic contrast agents
|
US6551576B1
(en)
|
1989-12-22 |
2003-04-22 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Container with multi-phase composition for use in diagnostic and therapeutic applications
|
US6088613A
(en)
|
1989-12-22 |
2000-07-11 |
Imarx Pharmaceutical Corp. |
Method of magnetic resonance focused surgical and therapeutic ultrasound
|
US5585112A
(en)
*
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
US5542935A
(en)
*
|
1989-12-22 |
1996-08-06 |
Imarx Pharmaceutical Corp. |
Therapeutic delivery systems related applications
|
US5352435A
(en)
*
|
1989-12-22 |
1994-10-04 |
Unger Evan C |
Ionophore containing liposomes for ultrasound imaging
|
US5773024A
(en)
*
|
1989-12-22 |
1998-06-30 |
Imarx Pharmaceutical Corp. |
Container with multi-phase composition for use in diagnostic and therapeutic applications
|
US5580575A
(en)
*
|
1989-12-22 |
1996-12-03 |
Imarx Pharmaceutical Corp. |
Therapeutic drug delivery systems
|
US6001335A
(en)
*
|
1989-12-22 |
1999-12-14 |
Imarx Pharmaceutical Corp. |
Contrasting agents for ultrasonic imaging and methods for preparing the same
|
US5882678A
(en)
*
|
1990-01-12 |
1999-03-16 |
The Liposome Co, Inc. |
Interdigitation-fusion liposomes containing arachidonic acid metabolites
|
US5162361A
(en)
*
|
1990-04-10 |
1992-11-10 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Method of treating diseases associated with elevated levels of interleukin 1
|
US20060084797A1
(en)
*
|
1990-06-11 |
2006-04-20 |
Gilead Sciences, Inc. |
High affinity TGFbeta nucleic acid ligands and inhibitors
|
US6465188B1
(en)
*
|
1990-06-11 |
2002-10-15 |
Gilead Sciences, Inc. |
Nucleic acid ligand complexes
|
US20030113369A1
(en)
*
|
1991-01-16 |
2003-06-19 |
Martin Francis J. |
Liposomes with enhanced circulation time and method of treatment
|
US5205290A
(en)
|
1991-04-05 |
1993-04-27 |
Unger Evan C |
Low density microspheres and their use as contrast agents for computed tomography
|
US5874062A
(en)
*
|
1991-04-05 |
1999-02-23 |
Imarx Pharmaceutical Corp. |
Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
|
JP3220180B2
(ja)
*
|
1991-05-23 |
2001-10-22 |
三菱化学株式会社 |
薬剤含有タンパク質結合リポソーム
|
GB9111611D0
(en)
*
|
1991-05-30 |
1991-07-24 |
Sandoz Ltd |
Liposomes
|
JP4074658B2
(ja)
|
1992-04-03 |
2008-04-09 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
自己構築ポリヌクレオチド送達システム
|
ZA933926B
(en)
*
|
1992-06-17 |
1994-01-03 |
Amgen Inc |
Polyoxymethylene-oxyethylene copolymers in conjuction with blomolecules
|
ES2130406T5
(es)
*
|
1992-08-05 |
2003-12-16 |
Meito Sangyo Kk |
Material compuesto de pequeño diametro compuesto de carboxipolisacarido soluble en agua y oxido de hierro magnetico.
|
NL9201722A
(nl)
*
|
1992-10-05 |
1994-05-02 |
Stichting Tech Wetenschapp |
Farmaceutische samenstelling voor de plaatsgebonden afgifte van een stolsel oplossend eiwit en werkwijze voor de bereiding daarvan.
|
DE4236237A1
(de)
*
|
1992-10-27 |
1994-04-28 |
Behringwerke Ag |
Prodrugs, ihre Herstellung und Verwendung als Arzneimittel
|
US6764693B1
(en)
*
|
1992-12-11 |
2004-07-20 |
Amaox, Ltd. |
Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants
|
JP3351476B2
(ja)
*
|
1993-01-22 |
2002-11-25 |
三菱化学株式会社 |
リン脂質誘導体及びそれを含有するリポソーム
|
US5395619A
(en)
*
|
1993-03-03 |
1995-03-07 |
Liposome Technology, Inc. |
Lipid-polymer conjugates and liposomes
|
US6180134B1
(en)
*
|
1993-03-23 |
2001-01-30 |
Sequus Pharmaceuticals, Inc. |
Enhanced ciruclation effector composition and method
|
AU6368394A
(en)
*
|
1993-03-23 |
1994-10-11 |
Liposome Technology, Inc. |
Polymer-polypeptide composition and method
|
US6326353B1
(en)
*
|
1993-03-23 |
2001-12-04 |
Sequus Pharmaceuticals, Inc. |
Enhanced circulation effector composition and method
|
AU6785094A
(en)
*
|
1993-05-07 |
1994-12-12 |
Sequus Pharmaceuticals, Inc. |
Subcutaneous liposome delivery method
|
US5681811A
(en)
*
|
1993-05-10 |
1997-10-28 |
Protein Delivery, Inc. |
Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
|
US6191105B1
(en)
|
1993-05-10 |
2001-02-20 |
Protein Delivery, Inc. |
Hydrophilic and lipophilic balanced microemulsion formulations of free-form and/or conjugation-stabilized therapeutic agents such as insulin
|
US20050181976A1
(en)
*
|
1993-05-10 |
2005-08-18 |
Ekwuribe Nnochiri N. |
Amphiphilic oligomers
|
US5359030A
(en)
*
|
1993-05-10 |
1994-10-25 |
Protein Delivery, Inc. |
Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
|
DE69429511T2
(de)
*
|
1993-05-21 |
2002-05-16 |
Liposome Co Inc |
Reduzierung von durch liposome induzierte physiologischen gegenreaktionen
|
US5744155A
(en)
*
|
1993-08-13 |
1998-04-28 |
Friedman; Doron |
Bioadhesive emulsion preparations for enhanced drug delivery
|
US5514670A
(en)
*
|
1993-08-13 |
1996-05-07 |
Pharmos Corporation |
Submicron emulsions for delivery of peptides
|
DE69424680T2
(de)
*
|
1993-10-25 |
2000-09-28 |
Liposome Co Inc |
Liposomale defensine
|
US5415869A
(en)
*
|
1993-11-12 |
1995-05-16 |
The Research Foundation Of State University Of New York |
Taxol formulation
|
US5468499A
(en)
*
|
1993-11-15 |
1995-11-21 |
Ohio State University |
Liposomes containing the salt of phosphoramide mustard and related compounds
|
US7083572B2
(en)
*
|
1993-11-30 |
2006-08-01 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Therapeutic delivery systems
|
CA2178902A1
(en)
*
|
1993-12-14 |
1995-06-22 |
Drew Pardoll |
Controlled release of pharmaceutically active substances for immunotherapy
|
US6773719B2
(en)
|
1994-03-04 |
2004-08-10 |
Esperion Luv Development, Inc. |
Liposomal compositions, and methods of using liposomal compositions to treat dislipidemias
|
US6312719B1
(en)
*
|
1994-03-04 |
2001-11-06 |
The University Of British Columbia |
Liposome compositions and methods for the treatment of atherosclerosis
|
US20010055581A1
(en)
*
|
1994-03-18 |
2001-12-27 |
Lawrence Tamarkin |
Composition and method for delivery of biologically-active factors
|
US5736121A
(en)
*
|
1994-05-23 |
1998-04-07 |
Imarx Pharmaceutical Corp. |
Stabilized homogenous suspensions as computed tomography contrast agents
|
DE4423131A1
(de)
*
|
1994-07-01 |
1996-01-04 |
Bayer Ag |
Neue hIL-4-Mutantenproteine als Antagonisten oder partielle Agonisten des humanen Interleukin 4
|
US5626862A
(en)
|
1994-08-02 |
1997-05-06 |
Massachusetts Institute Of Technology |
Controlled local delivery of chemotherapeutic agents for treating solid tumors
|
US6132764A
(en)
|
1994-08-05 |
2000-10-17 |
Targesome, Inc. |
Targeted polymerized liposome diagnostic and treatment agents
|
US5512294A
(en)
*
|
1994-08-05 |
1996-04-30 |
Li; King C. |
Targeted polymerized liposome contrast agents
|
US6309853B1
(en)
|
1994-08-17 |
2001-10-30 |
The Rockfeller University |
Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
|
US6001968A
(en)
|
1994-08-17 |
1999-12-14 |
The Rockefeller University |
OB polypeptides, modified forms and compositions
|
US6124448A
(en)
*
|
1994-08-17 |
2000-09-26 |
The Rockfeller University |
Nucleic acid primers and probes for the mammalian OB gene
|
US6471956B1
(en)
|
1994-08-17 |
2002-10-29 |
The Rockefeller University |
Ob polypeptides, modified forms and compositions thereto
|
US6350730B1
(en)
|
1994-08-17 |
2002-02-26 |
The Rockefeller University |
OB polypeptides and modified forms as modulators of body weight
|
US6048837A
(en)
*
|
1994-08-17 |
2000-04-11 |
The Rockefeller University |
OB polypeptides as modulators of body weight
|
US6124439A
(en)
*
|
1994-08-17 |
2000-09-26 |
The Rockefeller University |
OB polypeptide antibodies and method of making
|
US5885613A
(en)
*
|
1994-09-30 |
1999-03-23 |
The University Of British Columbia |
Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
|
US5820873A
(en)
*
|
1994-09-30 |
1998-10-13 |
The University Of British Columbia |
Polyethylene glycol modified ceramide lipids and liposome uses thereof
|
EP1179340A3
(en)
*
|
1994-09-30 |
2003-05-07 |
INEX Pharmaceutical Corp. |
Compositions for the introduction of polyanionic materials into cells
|
CN1080575C
(zh)
*
|
1994-10-14 |
2002-03-13 |
蛋白质传送股份有限公司 |
结合稳定的多肽组合物、其治疗、诊断制剂及其制备和使用方法
|
PT785773E
(pt)
*
|
1994-10-14 |
2001-05-31 |
Liposome Co Inc |
Lipossomas de eteres lipidicos e sua utilizacao terapeutica
|
US6214388B1
(en)
*
|
1994-11-09 |
2001-04-10 |
The Regents Of The University Of California |
Immunoliposomes that optimize internalization into target cells
|
US6743779B1
(en)
|
1994-11-29 |
2004-06-01 |
Imarx Pharmaceutical Corp. |
Methods for delivering compounds into a cell
|
US5827531A
(en)
*
|
1994-12-02 |
1998-10-27 |
The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration |
Microcapsules and methods for making
|
US5795587A
(en)
*
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US6008202A
(en)
*
|
1995-01-23 |
1999-12-28 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US5830430A
(en)
*
|
1995-02-21 |
1998-11-03 |
Imarx Pharmaceutical Corp. |
Cationic lipids and the use thereof
|
IL112834A
(en)
*
|
1995-03-01 |
2000-12-06 |
Yeda Res & Dev |
Pharmaceutical compositions for controlled release of soluble receptors
|
US5658588A
(en)
*
|
1995-03-31 |
1997-08-19 |
University Of Cincinnati |
Fibrinogen-coated liposomes
|
GB9509016D0
(en)
*
|
1995-05-03 |
1995-06-21 |
Royal Free Hosp School Med |
Tissue entrapment
|
US8071737B2
(en)
*
|
1995-05-04 |
2011-12-06 |
Glead Sciences, Inc. |
Nucleic acid ligand complexes
|
US6420549B1
(en)
|
1995-06-06 |
2002-07-16 |
Isis Pharmaceuticals, Inc. |
Oligonucleotide analogs having modified dimers
|
US5997898A
(en)
*
|
1995-06-06 |
1999-12-07 |
Imarx Pharmaceutical Corp. |
Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
|
US6033645A
(en)
*
|
1996-06-19 |
2000-03-07 |
Unger; Evan C. |
Methods for diagnostic imaging by regulating the administration rate of a contrast agent
|
US5981501A
(en)
*
|
1995-06-07 |
1999-11-09 |
Inex Pharmaceuticals Corp. |
Methods for encapsulating plasmids in lipid bilayers
|
US6231834B1
(en)
|
1995-06-07 |
2001-05-15 |
Imarx Pharmaceutical Corp. |
Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same
|
US6673364B1
(en)
|
1995-06-07 |
2004-01-06 |
The University Of British Columbia |
Liposome having an exchangeable component
|
US7422902B1
(en)
|
1995-06-07 |
2008-09-09 |
The University Of British Columbia |
Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
|
US6521211B1
(en)
|
1995-06-07 |
2003-02-18 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Methods of imaging and treatment with targeted compositions
|
ES2231819T3
(es)
*
|
1995-06-07 |
2005-05-16 |
Inex Pharmaceuticals Corp |
Particulas de lipido-acido nucleico preparadas a traves de un intermedio complejo de lipido-acido nucleico hidrofobo y uso para transferir genes.
|
US6139819A
(en)
|
1995-06-07 |
2000-10-31 |
Imarx Pharmaceutical Corp. |
Targeted contrast agents for diagnostic and therapeutic use
|
JPH11511128A
(ja)
*
|
1995-08-01 |
1999-09-28 |
ノバルティス・アクチエンゲゼルシャフト |
リポソームオリゴヌクレオチド組成物
|
US6051600A
(en)
*
|
1995-09-12 |
2000-04-18 |
Mayhew; Eric |
Liposomal hydrolysis-promoting hydrophobic taxane derivatives
|
US6107332A
(en)
|
1995-09-12 |
2000-08-22 |
The Liposome Company, Inc. |
Hydrolysis-promoting hydrophobic taxane derivatives
|
US5834025A
(en)
|
1995-09-29 |
1998-11-10 |
Nanosystems L.L.C. |
Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions
|
CA2231547A1
(en)
*
|
1995-10-11 |
1997-04-17 |
Kevin Jon Williams |
Liposomal compositions and methods of using them
|
US5858397A
(en)
*
|
1995-10-11 |
1999-01-12 |
University Of British Columbia |
Liposomal formulations of mitoxantrone
|
US6936439B2
(en)
*
|
1995-11-22 |
2005-08-30 |
Amgen Inc. |
OB fusion protein compositions and methods
|
US20030040467A1
(en)
*
|
1998-06-15 |
2003-02-27 |
Mary Ann Pelleymounter |
Ig/ob fusions and uses thereof.
|
US5626654A
(en)
|
1995-12-05 |
1997-05-06 |
Xerox Corporation |
Ink compositions containing liposomes
|
US5817856A
(en)
*
|
1995-12-11 |
1998-10-06 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Radiation-protective phospholipid and method
|
US7002027B1
(en)
|
1996-01-08 |
2006-02-21 |
Canji, Inc. |
Compositions and methods for therapeutic use
|
US5789244A
(en)
*
|
1996-01-08 |
1998-08-04 |
Canji, Inc. |
Compositions and methods for the treatment of cancer using recombinant viral vector delivery systems
|
US20040014709A1
(en)
*
|
1996-01-08 |
2004-01-22 |
Canji, Inc. |
Methods and compositions for interferon therapy
|
US6392069B2
(en)
|
1996-01-08 |
2002-05-21 |
Canji, Inc. |
Compositions for enhancing delivery of nucleic acids to cells
|
IL125073A0
(en)
|
1996-01-08 |
1999-01-26 |
Genentech Inc |
Wsx receptor and ligands
|
US6096336A
(en)
*
|
1996-01-30 |
2000-08-01 |
The Stehlin Foundation For Cancer Research |
Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
|
US5908624A
(en)
*
|
1996-06-27 |
1999-06-01 |
Albany Medical College |
Antigenic modulation of cells
|
US5965159A
(en)
*
|
1996-02-16 |
1999-10-12 |
The Liposome Company, Inc. |
Etherlipid-containing multiple lipid liposomes
|
USRE39042E1
(en)
*
|
1996-02-16 |
2006-03-28 |
The Liposome Company, Inc. |
Etherlipid-containing multiple lipid liposomes
|
US5942246A
(en)
*
|
1996-02-16 |
1999-08-24 |
The Liposome Company, Inc. |
Etherlipid containing multiple lipid liposomes
|
US6667053B1
(en)
|
1996-02-16 |
2003-12-23 |
Elan Pharmaceuticals, Inc. |
D and L etherlipid stereoisomers and liposomes
|
US6007839A
(en)
*
|
1996-02-16 |
1999-12-28 |
The Liposome Company, Inc. |
Preparation of pharmaceutical compositions containing etherlipid-containing multiple lipid liposomes
|
EP0914094A4
(en)
|
1996-03-28 |
2000-03-01 |
Univ Illinois |
MATERIALS AND METHOD FOR PRODUCING IMPROVED LIPOSOMAL AGENTS
|
JP2001507207A
(ja)
|
1996-05-01 |
2001-06-05 |
イマアーレクス・フアーマシユーチカル・コーポレーシヨン |
化合物を細胞に送達する方法
|
US9096636B2
(en)
|
1996-06-06 |
2015-08-04 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
US20070275921A1
(en)
*
|
1996-06-06 |
2007-11-29 |
Isis Pharmaceuticals, Inc. |
Oligomeric Compounds That Facilitate Risc Loading
|
US5898031A
(en)
|
1996-06-06 |
1999-04-27 |
Isis Pharmaceuticals, Inc. |
Oligoribonucleotides for cleaving RNA
|
US7812149B2
(en)
|
1996-06-06 |
2010-10-12 |
Isis Pharmaceuticals, Inc. |
2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
|
US20050042647A1
(en)
*
|
1996-06-06 |
2005-02-24 |
Baker Brenda F. |
Phosphorous-linked oligomeric compounds and their use in gene modulation
|
US5919480A
(en)
|
1996-06-24 |
1999-07-06 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Liposomal influenza vaccine composition and method
|
US8007784B1
(en)
|
1996-06-27 |
2011-08-30 |
Albany Medical College |
Antigenic modulation of cells
|
US7368129B1
(en)
|
1996-08-14 |
2008-05-06 |
Nutrimed Biotech |
Amphiphilic materials and liposome formulations thereof
|
US6284267B1
(en)
|
1996-08-14 |
2001-09-04 |
Nutrimed Biotech |
Amphiphilic materials and liposome formulations thereof
|
US6159462A
(en)
*
|
1996-08-16 |
2000-12-12 |
Genentech, Inc. |
Uses of Wnt polypeptides
|
US5851984A
(en)
*
|
1996-08-16 |
1998-12-22 |
Genentech, Inc. |
Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
|
ES2208946T3
(es)
*
|
1996-08-23 |
2004-06-16 |
Sequus Pharmaceuticals, Inc. |
Liposomas que contienen un compuesto de cisplatino.
|
ES2208936T3
(es)
|
1996-08-26 |
2004-06-16 |
Transgene S.A. |
Complejos de lipidos cationicos-acidos nucleicos.
|
US6414139B1
(en)
|
1996-09-03 |
2002-07-02 |
Imarx Therapeutics, Inc. |
Silicon amphiphilic compounds and the use thereof
|
US5846517A
(en)
*
|
1996-09-11 |
1998-12-08 |
Imarx Pharmaceutical Corp. |
Methods for diagnostic imaging using a renal contrast agent and a vasodilator
|
ES2189974T3
(es)
*
|
1996-09-11 |
2003-07-16 |
Imarx Pharmaceutical Corp |
Procedimientos mejorados para la obtencion de imagenes de diagnostico usando un agente de contraste y un vasodilatador.
|
US6224903B1
(en)
|
1996-10-11 |
2001-05-01 |
Sequus Pharmaceuticals, Inc. |
Polymer-lipid conjugate for fusion of target membranes
|
US6056973A
(en)
|
1996-10-11 |
2000-05-02 |
Sequus Pharmaceuticals, Inc. |
Therapeutic liposome composition and method of preparation
|
EP0932390A1
(en)
*
|
1996-10-11 |
1999-08-04 |
Sequus Pharmaceuticals, Inc. |
Therapeutic liposome composition and method
|
TW520297B
(en)
*
|
1996-10-11 |
2003-02-11 |
Sequus Pharm Inc |
Fusogenic liposome composition and method
|
DK0964690T3
(da)
*
|
1996-10-15 |
2003-10-20 |
Liposome Co Inc |
Peptid-lipidkonjugater, liposomer og liposomal lægemiddeladministration
|
US6339069B1
(en)
*
|
1996-10-15 |
2002-01-15 |
Elan Pharmaceuticalstechnologies, Inc. |
Peptide-lipid conjugates, liposomes and lipsomal drug delivery
|
US6331289B1
(en)
|
1996-10-28 |
2001-12-18 |
Nycomed Imaging As |
Targeted diagnostic/therapeutic agents having more than one different vectors
|
AU733495B2
(en)
*
|
1996-10-28 |
2001-05-17 |
Nycomed Imaging As |
Improvements in or relating to diagnostic/therapeutic agents
|
US6261537B1
(en)
*
|
1996-10-28 |
2001-07-17 |
Nycomed Imaging As |
Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors
|
US20070036722A1
(en)
*
|
1996-10-28 |
2007-02-15 |
Pal Rongved |
Separation processes
|
US5827533A
(en)
*
|
1997-02-06 |
1998-10-27 |
Duke University |
Liposomes containing active agents aggregated with lipid surfactants
|
AU6161898A
(en)
*
|
1997-02-14 |
1998-09-08 |
Regents Of The University Of California, The |
Lamellar gels and methods for making and regulating
|
US6537246B1
(en)
|
1997-06-18 |
2003-03-25 |
Imarx Therapeutics, Inc. |
Oxygen delivery agents and uses for the same
|
US6120751A
(en)
*
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
US6090800A
(en)
|
1997-05-06 |
2000-07-18 |
Imarx Pharmaceutical Corp. |
Lipid soluble steroid prodrugs
|
US6143276A
(en)
*
|
1997-03-21 |
2000-11-07 |
Imarx Pharmaceutical Corp. |
Methods for delivering bioactive agents to regions of elevated temperatures
|
BR9809064A
(pt)
|
1997-04-03 |
2002-01-02 |
Guilford Pharm Inc |
Polìmeros biodegradáveis de poliéster de tereftalato-polifosfato, composições, artigos e métodos para fazer e usar os mesmos
|
SI1325932T1
(no)
|
1997-04-07 |
2005-08-31 |
Genentech Inc |
|
DE69841815D1
(de)
|
1997-04-07 |
2010-09-16 |
Genentech Inc |
Anti-VEGF Antikörper
|
WO1998044910A1
(en)
*
|
1997-04-09 |
1998-10-15 |
Philipp Lang |
NEW TECHNIQUE TO MONITOR DRUG DELIVERY NONINVASIVELY $i(IN VIVO)
|
US20020039594A1
(en)
*
|
1997-05-13 |
2002-04-04 |
Evan C. Unger |
Solid porous matrices and methods of making and using the same
|
US6416740B1
(en)
|
1997-05-13 |
2002-07-09 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Acoustically active drug delivery systems
|
AU733310C
(en)
*
|
1997-05-14 |
2001-11-29 |
University Of British Columbia, The |
High efficiency encapsulation of charged therapeutic agents in lipid vesicles
|
DE19724796A1
(de)
*
|
1997-06-06 |
1998-12-10 |
Max Delbrueck Centrum |
Mittel zur Antitumortherapie
|
US6663899B2
(en)
*
|
1997-06-13 |
2003-12-16 |
Genentech, Inc. |
Controlled release microencapsulated NGF formulation
|
US6113947A
(en)
*
|
1997-06-13 |
2000-09-05 |
Genentech, Inc. |
Controlled release microencapsulated NGF formulation
|
US6217886B1
(en)
|
1997-07-14 |
2001-04-17 |
The Board Of Trustees Of The University Of Illinois |
Materials and methods for making improved micelle compositions
|
US6548047B1
(en)
|
1997-09-15 |
2003-04-15 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Thermal preactivation of gaseous precursor filled compositions
|
ATE535232T1
(de)
|
1997-09-18 |
2011-12-15 |
Pacira Pharmaceuticals Inc |
Retardierte freisetzung liposomaler anesthetischer zusammensetzungen
|
US6734171B1
(en)
|
1997-10-10 |
2004-05-11 |
Inex Pharmaceuticals Corp. |
Methods for encapsulating nucleic acids in lipid bilayers
|
US6083923A
(en)
*
|
1997-10-31 |
2000-07-04 |
Isis Pharmaceuticals Inc. |
Liposomal oligonucleotide compositions for modulating RAS gene expression
|
US7229841B2
(en)
*
|
2001-04-30 |
2007-06-12 |
Cytimmune Sciences, Inc. |
Colloidal metal compositions and methods
|
JP4575592B2
(ja)
|
1997-11-14 |
2010-11-04 |
パシラ ファーマシューティカルズ インコーポレーテッド |
多小胞リポソームの製造
|
US7192589B2
(en)
|
1998-09-16 |
2007-03-20 |
Genentech, Inc. |
Treatment of inflammatory disorders with STIgMA immunoadhesins
|
EP1481990B1
(en)
|
1997-11-21 |
2007-06-06 |
Genentech, Inc. |
A-33 related antigens and their pharmacological uses
|
US6787132B1
(en)
*
|
1997-12-04 |
2004-09-07 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Combined chemo-immunotherapy with liposomal drugs and cytokines
|
JP2001524512A
(ja)
*
|
1997-12-04 |
2001-12-04 |
イーサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム |
リポソーム薬物およびサイトカインを用いた組み合せ化学免疫療法
|
EP1947119A3
(en)
|
1997-12-12 |
2012-12-19 |
Genentech, Inc. |
Treatment of cancer with anti-erb2 antibodies in combination with a chemotherapeutic agent
|
US6123923A
(en)
|
1997-12-18 |
2000-09-26 |
Imarx Pharmaceutical Corp. |
Optoacoustic contrast agents and methods for their use
|
US20010003580A1
(en)
|
1998-01-14 |
2001-06-14 |
Poh K. Hui |
Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
|
ATE438720T1
(de)
|
1998-02-04 |
2009-08-15 |
Genentech Inc |
Verwendung des heregulins als epithelzellenwachstumsfaktor
|
AU753196B2
(en)
*
|
1998-02-09 |
2002-10-10 |
Bracco Research S.A. |
Targeted delivery of biologically active media
|
US6312685B1
(en)
|
1998-03-13 |
2001-11-06 |
Timothy C. Fisher |
Red blood cells covalently bound with two different polyethylene glycol derivatives
|
US6942859B2
(en)
|
1998-03-13 |
2005-09-13 |
University Of Southern California |
Red blood cells covalently bound with polymers
|
ES2313778T3
(es)
|
1998-03-17 |
2009-03-01 |
Genentech, Inc. |
Polipeptidos homologos de vegf y de bmp1.
|
JP2002507567A
(ja)
*
|
1998-03-25 |
2002-03-12 |
ラージ スケール バイオロジー コーポレイション |
血管形成を阻害するための安息香酸誘導体
|
US6433012B1
(en)
*
|
1998-03-25 |
2002-08-13 |
Large Scale Biology Corp. |
Method for inhibiting inflammatory disease
|
US6858706B2
(en)
|
1998-04-07 |
2005-02-22 |
St. Jude Children's Research Hospital |
Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
|
WO1999055306A1
(en)
*
|
1998-04-27 |
1999-11-04 |
Opperbas Holding B.V. |
Pharmaceutical composition comprising factor viii and neutral liposomes
|
US6986902B1
(en)
*
|
1998-04-28 |
2006-01-17 |
Inex Pharmaceuticals Corporation |
Polyanionic polymers which enhance fusogenicity
|
US6448224B1
(en)
|
1998-05-06 |
2002-09-10 |
St. Jude Children's Research Hospital |
Antibiotics and methods of using the same
|
US6331407B1
(en)
|
1998-05-06 |
2001-12-18 |
St. Jude Children's Research Hospital |
Antibiotics and methods of using the same
|
US6169078B1
(en)
*
|
1998-05-12 |
2001-01-02 |
University Of Florida |
Materials and methods for the intracellular delivery of substances
|
EP3112468A1
(en)
|
1998-05-15 |
2017-01-04 |
Genentech, Inc. |
Il-17 homologous polypeptides and therapeutic uses thereof
|
EP2333069A3
(en)
|
1998-05-15 |
2011-09-14 |
Genentech, Inc. |
Therapeutic uses of IL-17 homologous polypeptides
|
EP1865061A3
(en)
|
1998-05-15 |
2007-12-19 |
Genentech, Inc. |
IL-17 homologous polypeptides and therapeutic uses thereof
|
ES2331901T3
(es)
|
1998-06-12 |
2010-01-19 |
Genentech, Inc. |
Anticuerpos monoclonales, anticuerpos que reaccionan de forma cruzada y procedimiento para la produccion de los mismos.
|
US6200598B1
(en)
*
|
1998-06-18 |
2001-03-13 |
Duke University |
Temperature-sensitive liposomal formulation
|
US6726925B1
(en)
*
|
1998-06-18 |
2004-04-27 |
Duke University |
Temperature-sensitive liposomal formulation
|
US20040229363A1
(en)
*
|
1998-06-24 |
2004-11-18 |
Ed Nolan |
High efficiency transfection based on low electric field strength, long pulse length
|
US20030022854A1
(en)
|
1998-06-25 |
2003-01-30 |
Dow Steven W. |
Vaccines using nucleic acid-lipid complexes
|
US20040247662A1
(en)
*
|
1998-06-25 |
2004-12-09 |
Dow Steven W. |
Systemic immune activation method using nucleic acid-lipid complexes
|
US6693086B1
(en)
*
|
1998-06-25 |
2004-02-17 |
National Jewish Medical And Research Center |
Systemic immune activation method using nucleic acid-lipid complexes
|
DE69940735D1
(de)
|
1998-07-17 |
2009-05-28 |
Pacira Pharmaceuticals Inc |
Biologisch abbaubare anordnungen zur kontrollierten freigabe eingeschlossener substanzen
|
US20020172678A1
(en)
|
2000-06-23 |
2002-11-21 |
Napoleone Ferrara |
EG-VEGF nucleic acids and polypeptides and methods of use
|
US6703381B1
(en)
|
1998-08-14 |
2004-03-09 |
Nobex Corporation |
Methods for delivery therapeutic compounds across the blood-brain barrier
|
DE69907243T2
(de)
*
|
1998-09-16 |
2004-02-19 |
Alza Corp., Mountain View |
In liposomen eingeschlossene topoisomerase inhibitoren
|
US6077709A
(en)
|
1998-09-29 |
2000-06-20 |
Isis Pharmaceuticals Inc. |
Antisense modulation of Survivin expression
|
US6419709B1
(en)
|
1998-10-02 |
2002-07-16 |
Guilford Pharmaceuticals, Inc. |
Biodegradable terephthalate polyester-poly(Phosphite) compositions, articles, and methods of using the same
|
US6153212A
(en)
*
|
1998-10-02 |
2000-11-28 |
Guilford Pharmaceuticals Inc. |
Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
SI2319928T1
(sl)
*
|
1998-10-23 |
2013-08-30 |
Kirin-Amgen, Inc. |
Dimerni trombopoietinski peptidni mimetiki, ki se veĺ˝ejo na receptor mp1 in imajo trombopoietinsko aktivnost
|
EP1950300A3
(en)
|
1998-11-18 |
2011-03-23 |
Genentech, Inc. |
Antibody variants with higher binding affinity compared to parent antibodies
|
AU1740900A
(en)
*
|
1998-11-20 |
2000-06-13 |
Genentech Inc. |
Method of inhibiting angiogenesis
|
US6773911B1
(en)
*
|
1998-11-23 |
2004-08-10 |
Amgen Canada Inc. |
Apoptosis-inducing factor
|
EP1820859B9
(en)
|
1998-12-22 |
2009-10-28 |
Genentech, Inc. |
Methods and compositions for inhibiting neoplastic cell growth
|
DE69926536T3
(de)
|
1998-12-22 |
2013-09-12 |
Genentech, Inc. |
Antagonisten von vaskular-endothelialen zellwachstumsfaktoren und ihre anwendung
|
US6350464B1
(en)
|
1999-01-11 |
2002-02-26 |
Guilford Pharmaceuticals, Inc. |
Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same
|
US6818227B1
(en)
*
|
1999-02-08 |
2004-11-16 |
Alza Corporation |
Liposome composition and method for administration of a radiosensitizer
|
US6537585B1
(en)
|
1999-03-26 |
2003-03-25 |
Guilford Pharmaceuticals, Inc. |
Methods and compositions for treating solid tumors
|
US6379698B1
(en)
|
1999-04-06 |
2002-04-30 |
Isis Pharmaceuticals, Inc. |
Fusogenic lipids and vesicles
|
US7098192B2
(en)
|
1999-04-08 |
2006-08-29 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide modulation of STAT3 expression
|
US7112337B2
(en)
|
1999-04-23 |
2006-09-26 |
Alza Corporation |
Liposome composition for delivery of nucleic acid
|
JP2002543134A
(ja)
*
|
1999-04-29 |
2002-12-17 |
アルザ・コーポレーション |
薬物保持率を改善するためのリポソーム組成物
|
CA2270600A1
(en)
*
|
1999-05-03 |
2000-11-03 |
Infectio Recherche Inc. |
Method and formulations for the treatment of diseases, particularly those caused by human immunodeficiency virus and leishmania
|
EP1645292A1
(en)
|
1999-05-07 |
2006-04-12 |
Genentech, Inc. |
Treatment of autoimmune diseases with antagonists which bind to B cell surface markers
|
WO2000067760A1
(fr)
*
|
1999-05-11 |
2000-11-16 |
Sankyo Company, Limited |
Preparation de liposomes a base de medicaments antitumoraux liposolubles
|
US20040023874A1
(en)
*
|
2002-03-15 |
2004-02-05 |
Burgess Catherine E. |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
US20040229779A1
(en)
*
|
1999-05-14 |
2004-11-18 |
Ramesh Kekuda |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
US6974684B2
(en)
*
|
2001-08-08 |
2005-12-13 |
Curagen Corporation |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
US20040067490A1
(en)
*
|
2001-09-07 |
2004-04-08 |
Mei Zhong |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
EP1953173B1
(en)
|
1999-06-15 |
2009-11-18 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids endoding the same
|
US20030021792A1
(en)
*
|
2001-06-08 |
2003-01-30 |
Roben Paul W. |
Tissue-specific endothelial membrane proteins
|
US7169889B1
(en)
|
1999-06-19 |
2007-01-30 |
Biocon Limited |
Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
|
US6309633B1
(en)
|
1999-06-19 |
2001-10-30 |
Nobex Corporation |
Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same
|
CA2376849C
(en)
*
|
1999-06-24 |
2008-10-14 |
Kyowa Hakko Kogyo Co., Ltd. |
Method of inhibiting leakage of drug encapsulated in liposomes
|
EP2112167A3
(en)
|
1999-06-25 |
2010-12-22 |
Genentech, Inc. |
Humanized ANTI-ERBB2 antibodies and treatment with ANTI-ERBB2 antibodies
|
US6352996B1
(en)
|
1999-08-03 |
2002-03-05 |
The Stehlin Foundation For Cancer Research |
Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
|
GB9918670D0
(en)
|
1999-08-06 |
1999-10-13 |
Celltech Therapeutics Ltd |
Biological product
|
ATE438411T1
(de)
|
1999-08-27 |
2009-08-15 |
Genentech Inc |
Dosierung für die behandlung mit anti erbb2- antikörpern
|
KR20050004240A
(ko)
*
|
1999-08-31 |
2005-01-12 |
제넨테크, 인크. |
종양 치료용 조성물 및 방법
|
ATE362374T1
(de)
*
|
1999-09-03 |
2007-06-15 |
Amgen Inc |
Verfahren und zusammensetzungen zur prevention oder behandlung von krebs und von krebs assoziertem knochenverlust
|
AU7868400A
(en)
|
1999-10-08 |
2001-04-23 |
Alza Corporation |
Neutral-cationic lipid for nucleic acid and drug delivery
|
IT1315253B1
(it)
*
|
1999-10-22 |
2003-02-03 |
Novuspharma Spa |
Preparazione liposomiale di 6,9-bis-(2-amminoetil)ammino|benzog|isochinolin-5,10-dione dimaleato
|
US7067111B1
(en)
*
|
1999-10-25 |
2006-06-27 |
Board Of Regents, University Of Texas System |
Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
|
US6511676B1
(en)
*
|
1999-11-05 |
2003-01-28 |
Teni Boulikas |
Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
|
CA3016482A1
(en)
|
1999-11-30 |
2001-06-07 |
Mayo Foundation For Medical Education And Research |
B7-h1, a novel immunoregulatory molecule
|
EP1666495A1
(en)
|
1999-12-01 |
2006-06-07 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US6593308B2
(en)
|
1999-12-03 |
2003-07-15 |
The Regents Of The University Of California |
Targeted drug delivery with a hyaluronan ligand
|
CA2393595A1
(en)
*
|
1999-12-10 |
2001-06-14 |
Gigi Chiu |
Lipid carrier compositions with protected surface reactive functions
|
EP2258848B1
(en)
|
1999-12-23 |
2014-03-05 |
Genentech, Inc. |
Il-17 homologous polypeptide and therapeutic uses thereof
|
CA2395132A1
(en)
*
|
2000-01-05 |
2001-07-12 |
Imarx Therapeutics, Inc. |
Pharmaceutical formulations for the delivery of drugs having low aqueous solubility
|
US20040009229A1
(en)
*
|
2000-01-05 |
2004-01-15 |
Unger Evan Charles |
Stabilized nanoparticle formulations of camptotheca derivatives
|
EP1246917B1
(en)
*
|
2000-01-13 |
2009-03-04 |
Genentech, Inc. |
Human stra6 polypeptides
|
US20020055479A1
(en)
|
2000-01-18 |
2002-05-09 |
Cowsert Lex M. |
Antisense modulation of PTP1B expression
|
US6261840B1
(en)
|
2000-01-18 |
2001-07-17 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of PTP1B expression
|
CA2398514A1
(en)
*
|
2000-01-28 |
2001-08-02 |
Robert M. Abra |
Liposomes containing an entrapped compound in supersaturated solution
|
US20030176385A1
(en)
*
|
2000-02-15 |
2003-09-18 |
Jingfang Ju |
Antisense modulation of protein expression
|
JP4922824B2
(ja)
*
|
2000-04-03 |
2012-04-25 |
参天製薬株式会社 |
送達性物質およびそれを利用した薬物デリバリーシステム
|
DK2857516T3
(en)
|
2000-04-11 |
2017-08-07 |
Genentech Inc |
Multivalent antibodies and uses thereof
|
DK1272161T3
(da)
*
|
2000-04-12 |
2008-05-19 |
Liplasome Pharma As |
Lipid-baserede system til afgivelse af lægemidler mod parasitiske infektioner
|
JP2003530870A
(ja)
|
2000-04-21 |
2003-10-21 |
アムジエン・インコーポレーテツド |
Apo−AI/AIIペプチド誘導体
|
US6667300B2
(en)
*
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
US7030219B2
(en)
*
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
US6677136B2
(en)
|
2000-05-03 |
2004-01-13 |
Amgen Inc. |
Glucagon antagonists
|
WO2001085131A2
(en)
*
|
2000-05-11 |
2001-11-15 |
Celator Technologies Inc. |
Lipid carrier compositions for improved drug retention
|
US6680172B1
(en)
|
2000-05-16 |
2004-01-20 |
Regents Of The University Of Michigan |
Treatments and markers for cancers of the central nervous system
|
AU6531101A
(en)
|
2000-06-02 |
2001-12-17 |
Genentech Inc |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
JP5448284B2
(ja)
*
|
2000-06-02 |
2014-03-19 |
ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム |
エチレンジシステイン(ec)−薬物結合体
|
US20030072794A1
(en)
*
|
2000-06-09 |
2003-04-17 |
Teni Boulikas |
Encapsulation of plasmid DNA (lipogenes™) and therapeutic agents with nuclear localization signal/fusogenic peptide conjugates into targeted liposome complexes
|
EP2052742A1
(en)
|
2000-06-20 |
2009-04-29 |
Biogen Idec Inc. |
Treatment of B-cell associated diseases such as malignancies and autoimmune diseases using a cold anti-CD20 antibody/radiolabeled anti-CD22 antibody combination
|
DK2042597T3
(da)
|
2000-06-23 |
2014-08-11 |
Genentech Inc |
Sammensætninger og fremgangsmåder til diagnose og behandling af sygdomme, der involverer angiogenese
|
CA2709771A1
(en)
|
2000-06-23 |
2002-01-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
US20040023259A1
(en)
*
|
2000-07-26 |
2004-02-05 |
Luca Rastelli |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
ATE412009T1
(de)
|
2000-08-24 |
2008-11-15 |
Genentech Inc |
Methode zur inhibierung von il-22 induziertem pap1
|
EP1944317A3
(en)
|
2000-09-01 |
2008-09-17 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US20030133972A1
(en)
*
|
2000-10-11 |
2003-07-17 |
Targesome, Inc. |
Targeted multivalent macromolecules
|
US7045283B2
(en)
|
2000-10-18 |
2006-05-16 |
The Regents Of The University Of California |
Methods of high-throughput screening for internalizing antibodies
|
CA2429625C
(en)
|
2000-10-18 |
2012-05-01 |
Robert Sackstein |
Hematopoietic cell e-selectin/l-selectin ligand polypeptides and methods of use thereof
|
EP1341497A4
(en)
*
|
2000-11-02 |
2005-10-19 |
Smithkline Beecham Corp |
RECEPTOR-LIPID ANTAGONIST CONJUGATES AND DELIVERY VEHICLES CONTAINING THE SAME
|
DE10056136A1
(de)
*
|
2000-11-07 |
2002-05-16 |
Nemod New Modalities |
Verwendung von Schwangerschaftsproteinen, Liposomen, nativen Muzin-Fragmenten und Mimikry-Verbindungen zur Behandlung und Prophylaxe von entzündlichen Erkrankungen, zur Verhinderung der Metastasierung und zur Prophylaxe von Tumorerkrankungen
|
US8110218B2
(en)
*
|
2000-11-30 |
2012-02-07 |
The Research Foundation Of State University Of New York |
Compositions and methods for less immunogenic protein-lipid complexes
|
WO2002043665A2
(en)
*
|
2000-11-30 |
2002-06-06 |
The Research Foundation Of State University Of New York |
Ahf associated dispersion system and method for preparation
|
US7625584B2
(en)
*
|
2000-11-30 |
2009-12-01 |
The Research Foundation Of State University Of New York |
Method of complexing a protein by the use of a dispersed system and proteins thereof
|
AU2002248190A1
(en)
*
|
2000-11-30 |
2002-08-12 |
The Research Foundation Of State University Of New York |
Method of complexing a protein by the use of a dispersed system and proteins thereof
|
WO2002059145A1
(en)
*
|
2000-12-18 |
2002-08-01 |
Cubist Pharmaceuticals, Inc. |
Methods for preparing purified lipopeptides
|
US20060014674A1
(en)
*
|
2000-12-18 |
2006-01-19 |
Dennis Keith |
Methods for preparing purified lipopeptides
|
NZ554405A
(en)
*
|
2000-12-18 |
2009-04-30 |
Cubist Pharm Inc |
Method for preparing crystalline and crystal-like forms of purified lipopeptides
|
US20040077604A1
(en)
*
|
2001-12-19 |
2004-04-22 |
Lenard Lichtenberger |
Method and compositions employing formulations of lecithin oils and nsaids for protecting the gastrointestinal tract and providingenhanced therapeutic activity
|
US6964849B2
(en)
|
2001-01-11 |
2005-11-15 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
US20040043928A1
(en)
*
|
2001-08-02 |
2004-03-04 |
Ramesh Kekuda |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
US20020159996A1
(en)
|
2001-01-31 |
2002-10-31 |
Kandasamy Hariharan |
Use of CD23 antagonists for the treatment of neoplastic disorders
|
AR035779A1
(es)
|
2001-02-06 |
2004-07-14 |
Genetics Inst Llc |
Polipeptidos de fusion derivados de glicoproteina ib alfa de plaqueta y metodos de uso de los mismos
|
US6867183B2
(en)
*
|
2001-02-15 |
2005-03-15 |
Nobex Corporation |
Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
|
US7060675B2
(en)
*
|
2001-02-15 |
2006-06-13 |
Nobex Corporation |
Methods of treating diabetes mellitus
|
US7087726B2
(en)
|
2001-02-22 |
2006-08-08 |
Genentech, Inc. |
Anti-interferon-α antibodies
|
JP2004525916A
(ja)
*
|
2001-03-08 |
2004-08-26 |
ターゲサム・インコーポレーテッド |
安定化された治療剤および撮像剤
|
AU2002305094B2
(en)
*
|
2001-03-26 |
2007-01-11 |
Alza Corporation |
Liposome composition for improved intracellular delivery of a therapeutic agent
|
US20040126900A1
(en)
*
|
2001-04-13 |
2004-07-01 |
Barry Stephen E |
High affinity peptide- containing nanoparticles
|
WO2002087541A1
(en)
*
|
2001-04-30 |
2002-11-07 |
Protiva Biotherapeutics Inc. |
Lipid-based formulations for gene transfer
|
JP2004535388A
(ja)
*
|
2001-04-30 |
2004-11-25 |
ターゲティッド ジェネティクス コーポレイション |
脂質含有薬物送達複合体およびそれらの生成方法
|
GB0111279D0
(en)
*
|
2001-05-10 |
2001-06-27 |
Nycomed Imaging As |
Radiolabelled liposomes
|
EP1921088B1
(en)
|
2001-05-11 |
2014-10-08 |
Amgen Inc. |
Peptides and related molecules that bind to tall-1
|
JP2004528384A
(ja)
*
|
2001-05-15 |
2004-09-16 |
トランジェーヌ、ソシエテ、アノニム |
目的の物質を細胞中に導入するための複合体
|
US20020197253A1
(en)
*
|
2001-05-22 |
2002-12-26 |
Cheek Dennis J. |
Compositions and methods for promoting or inhibiting NDPK
|
WO2002094194A2
(en)
*
|
2001-05-22 |
2002-11-28 |
Duke University |
Compositions and methods for inhibiting metastasis
|
CN101653604A
(zh)
|
2001-05-30 |
2010-02-24 |
基因技术股份有限公司 |
抗ngf抗体用于治疗各种疾病
|
JP2004532252A
(ja)
*
|
2001-05-31 |
2004-10-21 |
スカイファーマ インコーポレーテッド |
リポソームおよびミクロスフェア中のナノ懸濁物のカプセル化
|
US6835802B2
(en)
*
|
2001-06-04 |
2004-12-28 |
Nobex Corporation |
Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
|
US6828305B2
(en)
*
|
2001-06-04 |
2004-12-07 |
Nobex Corporation |
Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US7713932B2
(en)
*
|
2001-06-04 |
2010-05-11 |
Biocon Limited |
Calcitonin drug-oligomer conjugates, and uses thereof
|
US6713452B2
(en)
*
|
2001-06-04 |
2004-03-30 |
Nobex Corporation |
Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6858580B2
(en)
*
|
2001-06-04 |
2005-02-22 |
Nobex Corporation |
Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6828297B2
(en)
|
2001-06-04 |
2004-12-07 |
Nobex Corporation |
Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
US7803915B2
(en)
*
|
2001-06-20 |
2010-09-28 |
Genentech, Inc. |
Antibody compositions for the diagnosis and treatment of tumor
|
US20050107595A1
(en)
*
|
2001-06-20 |
2005-05-19 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
ES2372321T3
(es)
|
2001-06-20 |
2012-01-18 |
Genentech, Inc. |
Composiciones y métodos para el diagnóstico y tratamiento de un tumor de pulmón.
|
EP2270024B1
(en)
|
2001-06-21 |
2018-10-24 |
Ionis Pharmaceuticals, Inc. |
Antisense modulation of superoxide dismutase 1, soluble expression
|
CN1827766B
(zh)
|
2001-06-28 |
2010-08-25 |
徐荣祥 |
体外细胞的培养方法
|
US20030087274A1
(en)
*
|
2001-07-05 |
2003-05-08 |
Anderson David W. |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
US20040029790A1
(en)
*
|
2001-07-05 |
2004-02-12 |
Meera Patturajan |
Novel human proteins, polynucleotides encoding them and methods of using the same
|
WO2003007914A2
(en)
*
|
2001-07-19 |
2003-01-30 |
Guilford Pharmaceuticals, Inc. |
Biocompatible polymer containing composition for treatment of prostate cancers
|
WO2003007915A2
(en)
*
|
2001-07-19 |
2003-01-30 |
Guilford Pharmaceuticals, Inc. |
Compositions for treatment of head and neck cancers, and methods of making and using the same
|
US7425545B2
(en)
|
2001-07-25 |
2008-09-16 |
Isis Pharmaceuticals, Inc. |
Modulation of C-reactive protein expression
|
US6964950B2
(en)
|
2001-07-25 |
2005-11-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of C-reactive protein expression
|
CZ2004300A3
(cs)
*
|
2001-07-29 |
2005-03-16 |
Yissum Research Development Company Of The Hebrew |
Osteogenní růstové oligopeptidy jako stimulátory krvetvorby
|
US20030096772A1
(en)
|
2001-07-30 |
2003-05-22 |
Crooke Rosanne M. |
Antisense modulation of acyl CoA cholesterol acyltransferase-2 expression
|
US7407943B2
(en)
|
2001-08-01 |
2008-08-05 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein B expression
|
US20040030096A1
(en)
*
|
2001-08-02 |
2004-02-12 |
Linda Gorman |
Novel human proteins, polynucleotides encoding them and methods of using the same
|
US7227014B2
(en)
|
2001-08-07 |
2007-06-05 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein (a) expression
|
JP2005502653A
(ja)
*
|
2001-08-20 |
2005-01-27 |
トランセーヴ・インコーポレーテッド |
肺ガンの治療方法
|
WO2003020702A2
(en)
|
2001-08-31 |
2003-03-13 |
The Rockefeller University |
Phosphodiesterase activity and regulation of phosphodiesterase 1-b-mediated signaling in brain
|
US20040235068A1
(en)
*
|
2001-09-05 |
2004-11-25 |
Levinson Arthur D. |
Methods for the identification of polypeptide antigens associated with disorders involving aberrant cell proliferation and compositions useful for the treatment of such disorders
|
US7196059B2
(en)
*
|
2001-09-07 |
2007-03-27 |
Biocon Limited |
Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
|
US7166571B2
(en)
*
|
2001-09-07 |
2007-01-23 |
Biocon Limited |
Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
|
US6913903B2
(en)
*
|
2001-09-07 |
2005-07-05 |
Nobex Corporation |
Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
|
US7312192B2
(en)
*
|
2001-09-07 |
2007-12-25 |
Biocon Limited |
Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
|
US7547673B2
(en)
*
|
2001-09-13 |
2009-06-16 |
The Johns Hopkins University |
Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production
|
KR101008758B1
(ko)
|
2001-09-18 |
2011-01-14 |
제넨테크, 인크. |
종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물
|
US7981863B2
(en)
|
2001-09-19 |
2011-07-19 |
Neuronova Ab |
Treatment of Parkinson's disease with PDGF
|
DE10148065A1
(de)
*
|
2001-09-28 |
2003-04-17 |
Max Planck Gesellschaft |
(Ester)-Lysolecithine in Liposomen
|
US20050260256A1
(en)
*
|
2001-09-28 |
2005-11-24 |
Hill Knut R |
Methods and apparatus for extrusion of vesicles at high pressure
|
US6750019B2
(en)
|
2001-10-09 |
2004-06-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of insulin-like growth factor binding protein 5 expression
|
EP2270231A3
(en)
|
2001-10-09 |
2011-04-27 |
ISIS Pharmaceuticals, Inc. |
Antisense modulation of insulin-like growth factor binding protein 5 expression
|
US20030199442A1
(en)
*
|
2001-10-09 |
2003-10-23 |
Alsobrook John P. |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
US7332474B2
(en)
*
|
2001-10-11 |
2008-02-19 |
Amgen Inc. |
Peptides and related compounds having thrombopoietic activity
|
IL161733A0
(en)
|
2001-11-02 |
2005-11-20 |
Insert Therapeutics Inc |
Methods and compositions for therapeutic use of rna interference
|
JP2005516897A
(ja)
*
|
2001-11-07 |
2005-06-09 |
イネックス ファーマシューティカルズ コーポレイション |
改善された粘膜のワクチン及びその使用方法
|
US20040219201A1
(en)
*
|
2001-12-06 |
2004-11-04 |
Yechezkel Barenholz |
Tempamine compositions and methods of use
|
US6965025B2
(en)
|
2001-12-10 |
2005-11-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of connective tissue growth factor expression
|
KR100623128B1
(ko)
|
2002-01-02 |
2006-09-14 |
제넨테크, 인크. |
종양의 진단 및 치료 방법 및 이를 위한 조성물
|
WO2003057165A2
(en)
|
2002-01-04 |
2003-07-17 |
The Rockefeller University |
COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF AMYLOID-β PEPTIDE-RELATED DISORDERS
|
US7781396B2
(en)
*
|
2002-01-31 |
2010-08-24 |
Tel Aviv University Future Technology Development L.P. |
Peptides directed for diagnosis and treatment of amyloid-associated disease
|
US20040052928A1
(en)
*
|
2002-09-06 |
2004-03-18 |
Ehud Gazit |
Peptides and methods using same for diagnosing and treating amyloid-associated diseases
|
AU2003215254A1
(en)
*
|
2002-02-13 |
2003-09-04 |
Immunology Laboratories, Inc. |
Compositions and methods for treatment of microbial infections
|
CA2476518A1
(en)
|
2002-02-22 |
2003-09-04 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
US20100311954A1
(en)
*
|
2002-03-01 |
2010-12-09 |
Xencor, Inc. |
Optimized Proteins that Target Ep-CAM
|
US20090042291A1
(en)
*
|
2002-03-01 |
2009-02-12 |
Xencor, Inc. |
Optimized Fc variants
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
US20070122406A1
(en)
|
2005-07-08 |
2007-05-31 |
Xencor, Inc. |
Optimized proteins that target Ep-CAM
|
US20030180712A1
(en)
|
2002-03-20 |
2003-09-25 |
Biostratum Ab |
Inhibition of the beta3 subunit of L-type Ca2+ channels
|
US20040009216A1
(en)
*
|
2002-04-05 |
2004-01-15 |
Rodrigueza Wendi V. |
Compositions and methods for dosing liposomes of certain sizes to treat or prevent disease
|
EP2011886A3
(en)
|
2002-04-16 |
2009-02-11 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
AU2003233008B2
(en)
*
|
2002-04-22 |
2008-04-24 |
Recopharma Ab |
Fusion polypeptides and methods for inhibiting microbial adhesion
|
US20040009944A1
(en)
*
|
2002-05-10 |
2004-01-15 |
Inex Pharmaceuticals Corporation |
Methylated immunostimulatory oligonucleotides and methods of using the same
|
US7199107B2
(en)
|
2002-05-23 |
2007-04-03 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of kinesin-like 1 expression
|
WO2005056606A2
(en)
*
|
2003-12-03 |
2005-06-23 |
Xencor, Inc |
Optimized antibodies that target the epidermal growth factor receptor
|
EP2305710A3
(en)
|
2002-06-03 |
2013-05-29 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
AU2003236521A1
(en)
*
|
2002-06-13 |
2003-12-31 |
Nobex Corporation |
Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus
|
DK1519714T3
(da)
|
2002-06-28 |
2011-01-31 |
Protiva Biotherapeutics Inc |
Fremgangsmåde og apparat til fremstilling af liposomer
|
CA2490959C
(en)
*
|
2002-07-02 |
2013-04-16 |
Board Of Regents, The University Of Texas System |
Radiolabeled compounds and liposomes and their methods of making and using the same
|
US20040247661A1
(en)
*
|
2002-07-03 |
2004-12-09 |
Dov Michaeli |
Liposomal vaccine
|
US20050169979A1
(en)
*
|
2002-07-03 |
2005-08-04 |
Dov Michaeli |
Liposomal vaccine
|
KR20050025306A
(ko)
*
|
2002-07-03 |
2005-03-14 |
애프톤 코포레이션 |
리포좀 백신
|
WO2004004649A2
(en)
|
2002-07-08 |
2004-01-15 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
MX337052B
(es)
*
|
2002-07-15 |
2016-02-11 |
Univ Texas |
Peptidos que se enlazan a fosfatidiletanolamina y sus usos en el tratamiento de infecciones virales y del cancer.
|
US7615223B2
(en)
*
|
2002-07-15 |
2009-11-10 |
Board Of Regents, The University Of Texas System |
Selected immunoconjugates for binding to aminophospholipids
|
US7625563B2
(en)
*
|
2002-07-15 |
2009-12-01 |
Board Of Regents, The University Of Texas System |
Cancer treatment methods using selected immunoconjugates for binding to aminophospholipids
|
US7572448B2
(en)
*
|
2002-07-15 |
2009-08-11 |
Board Of Regents, The University Of Texas System |
Combined cancer treatment methods using selected antibodies to aminophospholipids
|
US7622118B2
(en)
*
|
2002-07-15 |
2009-11-24 |
Board Of Regents, The University Of Texas System |
Cancer treatment methods using selected antibodies to aminophospholipids
|
US7678386B2
(en)
*
|
2002-07-15 |
2010-03-16 |
Board Of Regents The University Of Texas |
Liposomes coated with selected antibodies that bind to aminophospholipids
|
MXPA05000403A
(es)
|
2002-07-15 |
2005-07-22 |
Genentech Inc |
Metodos para identificar tumores que responden al tratamiento con anticuerpos contra erbb2.
|
US7714109B2
(en)
*
|
2002-07-15 |
2010-05-11 |
Board Of Regents, The University Of Texas System |
Combinations and kits for cancer treatment using selected antibodies to aminophospholipids
|
WO2004007693A2
(en)
*
|
2002-07-16 |
2004-01-22 |
University Of South Florida |
Human immunosuppressive protein
|
US20040161423A1
(en)
*
|
2002-07-18 |
2004-08-19 |
Sanjeev Kumar (Mendiratta) |
Polymer modified anti-angiogenic serpins
|
US9186322B2
(en)
*
|
2002-08-02 |
2015-11-17 |
Insmed Incorporated |
Platinum aggregates and process for producing the same
|
MXPA05001312A
(es)
*
|
2002-08-02 |
2005-08-03 |
Transave Inc |
Agregados de platino y proceso para producir los mismos.
|
US7425620B2
(en)
|
2002-08-14 |
2008-09-16 |
Scott Koenig |
FcγRIIB-specific antibodies and methods of use thereof
|
EP1393720A1
(en)
*
|
2002-08-27 |
2004-03-03 |
Universiteit Utrecht |
Vesicle-encapsulated corticosteroids for treatment of cancer
|
PL376536A1
(pl)
|
2002-08-28 |
2006-01-09 |
Immunex Corporation |
Kompozycje i sposoby leczenia chorób układu sercowo-naczyniowego
|
US20070231379A1
(en)
*
|
2002-08-29 |
2007-10-04 |
Slater James L |
Liposome-entrapped topoisomerase inhibitors
|
AR036316A1
(es)
*
|
2002-08-29 |
2004-08-25 |
Monte Verde S A |
Una composicion farmaceutica de liposomas de tamano pequeno y metodo de preparacion
|
US20080214437A1
(en)
*
|
2002-09-06 |
2008-09-04 |
Mohapatra Shyam S |
Methods and compositions for reducing activity of the atrial natriuretic peptide receptor and for treatment of diseases
|
US8071560B2
(en)
*
|
2004-02-17 |
2011-12-06 |
University Of South Florida |
Materials and methods for reducing inflammation by inhibition of the atrial natriuretic peptide receptor
|
AU2003268531A1
(en)
|
2002-09-06 |
2004-03-29 |
University Of South Florida |
Materials and methods for treatment of allergic diseases
|
CA2497334A1
(en)
|
2002-09-11 |
2004-03-25 |
Genentech, Inc. |
Novel compositions and methods for the treatment of immune related diseases
|
EP1539228B1
(en)
|
2002-09-11 |
2010-12-29 |
Genentech, Inc. |
Novel composition and methods for the treatment of immune related diseases
|
KR101360955B1
(ko)
*
|
2002-09-13 |
2014-02-10 |
레플리코르 인코포레이티드 |
비서열 상보적 항바이러스 올리고뉴클레오티드
|
US20050196382A1
(en)
*
|
2002-09-13 |
2005-09-08 |
Replicor, Inc. |
Antiviral oligonucleotides targeting viral families
|
JP2006515165A
(ja)
|
2002-09-16 |
2006-05-25 |
ジェネンテック・インコーポレーテッド |
免疫関連疾患の治療のための新規組成物と方法
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
JP2006513700A
(ja)
|
2002-09-25 |
2006-04-27 |
ジェネンテック・インコーポレーテッド |
乾癬の治療のための新規組成物と方法
|
EP1549767A4
(en)
|
2002-09-26 |
2006-06-07 |
Amgen Inc |
MODULATION OF FORKHEAD BOX O1A GENE EXPRESSION
|
CN101987871A
(zh)
|
2002-09-27 |
2011-03-23 |
赞科股份有限公司 |
优化的Fc变体及其产生方法
|
US20040062748A1
(en)
*
|
2002-09-30 |
2004-04-01 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
US7432351B1
(en)
|
2002-10-04 |
2008-10-07 |
Mayo Foundation For Medical Education And Research |
B7-H1 variants
|
WO2004032852A2
(en)
*
|
2002-10-04 |
2004-04-22 |
Rinat Neuroscience Corp. |
Methods for treating cardiac arrhythmia and preventing death due to cardiac arrhythmia using ngf antagonists
|
UA80447C2
(en)
*
|
2002-10-08 |
2007-09-25 |
|
Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic
|
PT1556083E
(pt)
*
|
2002-10-08 |
2011-03-17 |
Rinat Neuroscience Corp |
Métodos para tratar a dor pós-cirúrgica pela administração de um anticorpo contra o factor de crescimento nervoso e composições que contêm o mesmo
|
WO2005000194A2
(en)
|
2002-10-08 |
2005-01-06 |
Rinat Neuroscience Corp. |
Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody and compositions containing the same
|
WO2004032868A2
(en)
*
|
2002-10-09 |
2004-04-22 |
Rinat Neuroscience Corp. |
Methods of treating alzheimer's disease using antibodies directed against amyloid beta peptide and compositions thereof
|
EP1560597A4
(en)
*
|
2002-10-29 |
2007-06-27 |
Pharmacia Corp |
DIFFERENTIALLY EXPRESSED GENES INVOLVED IN CANCER, POLYPEPTIDES CODED THEREWITH, AND METHODS OF USING GENES
|
EP1576137A4
(en)
|
2002-10-29 |
2010-06-30 |
Genentech Inc |
COMPOSITIONS AND METHODS FOR TREATING DISEASES RELATED TO THE IMMUNE SYSTEM
|
EP1560839A4
(en)
|
2002-11-05 |
2008-04-23 |
Isis Pharmaceuticals Inc |
CHIMERIC OLIGOMER COMPOUNDS AND THEIR USE IN GENE MODULATION
|
WO2004044132A2
(en)
|
2002-11-05 |
2004-05-27 |
Isis Pharmaceuticals, Inc. |
Modified oligonucleotides for use in rna interference
|
US20040093198A1
(en)
*
|
2002-11-08 |
2004-05-13 |
Carbon Design Systems |
Hardware simulation with access restrictions
|
EP2364716A3
(en)
|
2002-11-08 |
2012-01-11 |
Genentech, Inc. |
Compositions and methods for the treatment of natural killer cell related diseases
|
AU2003285200A1
(en)
*
|
2002-11-09 |
2004-06-03 |
Nobex Corporation |
Modified carbamate-containing prodrugs and methods of synthesizing same
|
EP2336319A1
(en)
|
2002-11-13 |
2011-06-22 |
Genzyme Corporation |
Antisense modulation of apolipoprotein B expression
|
WO2004044181A2
(en)
|
2002-11-13 |
2004-05-27 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein b expression
|
US20050158375A1
(en)
*
|
2002-11-15 |
2005-07-21 |
Toshikiro Kimura |
Pharmaceutical composition containing liposomes for treating cancer
|
US7144999B2
(en)
|
2002-11-23 |
2006-12-05 |
Isis Pharmaceuticals, Inc. |
Modulation of hypoxia-inducible factor 1 alpha expression
|
BR0316560A
(pt)
|
2002-11-26 |
2005-10-04 |
Nobex Corp |
Conjugado de composto natriurético, formulação farmacêutica, método de tratar uma condição, método de preparação do conjugado de composto natriurético, conjugado de peptìdeo pró-polinatriurético modificado, análogo de peptìdeo natriurético, análogo de hbnp, composto, e, método de preparar um composto
|
US7648962B2
(en)
*
|
2002-11-26 |
2010-01-19 |
Biocon Limited |
Natriuretic compounds, conjugates, and uses thereof
|
AU2003302386B2
(en)
|
2002-11-26 |
2010-04-01 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
US7491699B2
(en)
|
2002-12-09 |
2009-02-17 |
Ramot At Tel Aviv University Ltd. |
Peptide nanostructures and methods of generating and using the same
|
KR20050090987A
(ko)
*
|
2002-12-19 |
2005-09-14 |
알자 코포레이션 |
혈관신생 조직 성장 치료 방법
|
US7569364B2
(en)
*
|
2002-12-24 |
2009-08-04 |
Pfizer Inc. |
Anti-NGF antibodies and methods using same
|
US9498530B2
(en)
|
2002-12-24 |
2016-11-22 |
Rinat Neuroscience Corp. |
Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
|
SI2263692T1
(sl)
|
2002-12-24 |
2020-10-30 |
Rinat Neuroscience Corp. |
Anti-NGF protitelesa in postopki, v katerih se le-ta uporabljajo
|
US8980310B2
(en)
*
|
2002-12-31 |
2015-03-17 |
Bharat Serums and Vaccines, Ltd. |
Non-pegylated long-circulating liposomes
|
ATE453381T1
(de)
|
2002-12-31 |
2010-01-15 |
Bharat Serums & Vaccines Ltd |
Nicht-pegylierte lang-zirkulierende liposome
|
EP2058275A1
(en)
*
|
2003-01-07 |
2009-05-13 |
Ramot at Tel-Aviv University Ltd. |
Peptide nanostructures encapsulating a foreign material and method of manufacturing same
|
US7169892B2
(en)
|
2003-01-10 |
2007-01-30 |
Astellas Pharma Inc. |
Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems
|
JPWO2004063216A1
(ja)
*
|
2003-01-10 |
2006-06-15 |
アステラス製薬株式会社 |
血中滞留および癌組織特異的薬物送達のためのコンジュゲート
|
US7468356B2
(en)
|
2003-02-11 |
2008-12-23 |
Antisense Therapeutics Ltd. |
Modulation of insulin like growth factor I receptor expression
|
DE602004030535D1
(de)
|
2003-02-19 |
2011-01-27 |
Rinat Neuroscience Corp |
Verfahren zur behandlung von schmerzen durch verabreichung eines nervenwachstumsfaktor-antagonisten und eines nsaid und diese enthaltende zusammensetzung
|
US7803781B2
(en)
|
2003-02-28 |
2010-09-28 |
Isis Pharmaceuticals, Inc. |
Modulation of growth hormone receptor expression and insulin-like growth factor expression
|
US7968115B2
(en)
|
2004-03-05 |
2011-06-28 |
Board Of Regents, The University Of Texas System |
Liposomal curcumin for treatment of cancer
|
US20040185559A1
(en)
|
2003-03-21 |
2004-09-23 |
Isis Pharmaceuticals Inc. |
Modulation of diacylglycerol acyltransferase 1 expression
|
CA2520864A1
(en)
|
2003-03-31 |
2004-10-21 |
Alza Corporation |
Lipid particles having asymmetric lipid coating and method of preparing same
|
EP1610763A2
(en)
*
|
2003-03-31 |
2006-01-04 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Stable liposomes or micelles comprising a sphingolipid and a peg-lipopolymer
|
ZA200507757B
(en)
|
2003-04-04 |
2007-01-31 |
Genentech Inc |
High concentration antibody and protein formulations
|
WO2004091657A2
(en)
|
2003-04-09 |
2004-10-28 |
Genentech, Inc. |
Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor
|
ES2307009T3
(es)
*
|
2003-04-15 |
2008-11-16 |
Opperbas Holding B.V. |
Composicion farmaceutica que contiene proteinas y/o polipeptidos y particulas coloidales.
|
US7598227B2
(en)
|
2003-04-16 |
2009-10-06 |
Isis Pharmaceuticals Inc. |
Modulation of apolipoprotein C-III expression
|
WO2004094457A2
(en)
*
|
2003-04-16 |
2004-11-04 |
Arizona Board Of Regents, Acting For And On Behalf Of, Arizona State University |
Stable rgd peptidomimetic composition
|
CA2522184A1
(en)
*
|
2003-04-17 |
2004-11-04 |
The Trustees Of Columbia University In The City Of New York |
Desmoglein 4 is a novel gene involved in hair growth
|
US7399853B2
(en)
|
2003-04-28 |
2008-07-15 |
Isis Pharmaceuticals |
Modulation of glucagon receptor expression
|
MXPA05012314A
(es)
|
2003-05-12 |
2006-04-18 |
Affymax Inc |
Radical separador para peptido modificado con polietilenglicol.
|
MXPA05012315A
(es)
|
2003-05-12 |
2006-04-18 |
Affymax Inc |
Compuestos poli(etilenglicol) modificados novedosos y usos de los mismos.
|
WO2005000896A2
(en)
*
|
2003-05-30 |
2005-01-06 |
Genentech, Inc. |
Polypeptides that bind an anti-tissue factor antibody and uses thereof
|
KR20060006975A
(ko)
|
2003-05-30 |
2006-01-20 |
제넨테크, 인크. |
항-vegf 항체를 사용한 치료
|
BRPI0410886A
(pt)
|
2003-06-03 |
2006-07-04 |
Isis Pharmaceuticals Inc |
composto de filamento duplo, composição farmacêutica, sal farmaceuticamente aceitável, métodos de modificação do ácido nucleico que codifica a survivina humana, de inibição da expressão da suvivina em células ou tecidos, e de tratamento de uma condição associada com a expressão ou superexpressão da suvivina, e, oligonucleotìdeo de rnai de filamento único
|
WO2004108088A2
(en)
*
|
2003-06-04 |
2004-12-16 |
Canji, Inc. |
Methods and compositions for interferon therapy
|
ES2323425T3
(es)
|
2003-06-06 |
2009-07-15 |
Genentech, Inc. |
Modulacion de la interaccion entre la cadena beta de hgf y c-met.
|
AU2004247737B2
(en)
|
2003-06-11 |
2009-04-23 |
Wyeth |
Platelet glycoprotein IB alpha variant fusion polypeptides and methods of use thereof
|
US7939058B2
(en)
*
|
2003-07-03 |
2011-05-10 |
University Of Southern California |
Uses of IL-12 in hematopoiesis
|
ES2354238T3
(es)
|
2003-07-03 |
2011-03-11 |
University Of Medicine And Dentistry Of New Jersey |
Genes como herramienta de diagnóstico para autismo.
|
NZ544317A
(en)
|
2003-07-08 |
2009-05-31 |
Genentech Inc |
IL-17 A/F heterologous polypeptides and therapeutic uses thereof
|
NZ544637A
(en)
*
|
2003-07-16 |
2010-04-30 |
Protiva Biotherapeutics Inc |
Lipid encapsulated interfering RNA
|
CN100431525C
(zh)
*
|
2003-07-17 |
2008-11-12 |
台湾东洋药品工业股份有限公司 |
脂质体悬浮液制造方法及含该法所制脂质体悬浮液的产物
|
US7683036B2
(en)
|
2003-07-31 |
2010-03-23 |
Regulus Therapeutics Inc. |
Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
|
WO2005011600A2
(en)
*
|
2003-07-31 |
2005-02-10 |
The Board Of Regents Of The University Of Texas System |
Sterile preparations of phospholipids and anti-inflammatory pharmaceuticals and methods for making and using same
|
WO2005019258A2
(en)
|
2003-08-11 |
2005-03-03 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
US20050043239A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Jason Douangpanya |
Methods of inhibiting immune responses stimulated by an endogenous factor
|
US20050054614A1
(en)
*
|
2003-08-14 |
2005-03-10 |
Diacovo Thomas G. |
Methods of inhibiting leukocyte accumulation
|
US7825235B2
(en)
|
2003-08-18 |
2010-11-02 |
Isis Pharmaceuticals, Inc. |
Modulation of diacylglycerol acyltransferase 2 expression
|
US8986731B2
(en)
*
|
2003-08-26 |
2015-03-24 |
Biolitec Pharma Marketing Ltd |
Pegylated liposomal formulations of hydrophobic photosensitizers for photodynamic therapy
|
ATE422880T1
(de)
*
|
2003-08-26 |
2009-03-15 |
Smithkline Beecham Corp |
Heterofunktionelle copolymere von glycerol und polyethylenglykol, ihre konjugate und zusammensetzungen
|
US20060115523A1
(en)
*
|
2004-12-01 |
2006-06-01 |
Konduri Kameswari S |
Sterically stabilized liposome and triamcinolone composition for treating the respiratory tract of a mammal
|
US8846079B1
(en)
|
2004-12-01 |
2014-09-30 |
Vgsk Technologies, Inc. |
Sterically stabilized carrier for aerosol therapeutics, compositions and methods for treating the respiratory tract of a mammal
|
US11324698B2
(en)
|
2003-08-28 |
2022-05-10 |
Vgsk Technologies, Inc. |
Sterically stabilized carrier for aerosol therapeutics, compositions and methods for treating the respiratory tract of a mammal
|
CN1867580B
(zh)
*
|
2003-09-03 |
2010-09-29 |
协和发酵麒麟株式会社 |
被甘油衍生物修饰的化合物
|
US20050233435A1
(en)
*
|
2003-09-04 |
2005-10-20 |
Nyu Medical Center |
Plasmodium axenic liver stages as a noninfectious whole organism malaria vaccine
|
US20070123480A1
(en)
*
|
2003-09-11 |
2007-05-31 |
Replicor Inc. |
Oligonucleotides targeting prion diseases
|
EP1664316B1
(en)
*
|
2003-09-15 |
2012-08-29 |
Protiva Biotherapeutics Inc. |
Polyethyleneglycol-modified lipid compounds and uses thereof
|
CA2539181A1
(en)
|
2003-09-18 |
2005-03-31 |
Isis Pharmaceuticals, Inc. |
Modulation of eif4e expression
|
JP4917889B2
(ja)
*
|
2003-09-25 |
2012-04-18 |
テル アヴィヴ ユニヴァーシティ フューチャー テクノロジー ディヴェロップメント エル.ピー. |
アミロイド関連疾患を処置するための組成物及びその使用方法
|
US8101720B2
(en)
*
|
2004-10-21 |
2012-01-24 |
Xencor, Inc. |
Immunoglobulin insertions, deletions and substitutions
|
US7625707B2
(en)
*
|
2003-10-02 |
2009-12-01 |
Ramot At Tel Aviv University Ltd. |
Antibacterial agents and methods of identifying and utilizing same
|
CA2541438C
(en)
|
2003-10-10 |
2013-11-26 |
Meditech Research Limited |
The modulation of hyaluronan synthesis and degradation in the treatment of disease
|
EP1675614A2
(en)
*
|
2003-10-11 |
2006-07-05 |
Inex Pharmaceuticals Corp. |
Methods and compositions for enhancing innate immunity and antibody dependent cellular cytotoxicity
|
TW200517114A
(en)
|
2003-10-15 |
2005-06-01 |
Combinatorx Inc |
Methods and reagents for the treatment of immunoinflammatory disorders
|
WO2005041870A2
(en)
|
2003-10-24 |
2005-05-12 |
Ader Enterprises, Inc. |
Composition and method for the treatment of eye disease
|
EP1677765A1
(en)
*
|
2003-10-24 |
2006-07-12 |
Alza Corporation |
Preparation of lipid particles
|
WO2005040163A1
(en)
*
|
2003-10-28 |
2005-05-06 |
Dr. Reddy's Laboratories Ltd |
Heterocyclic compounds that block the effects of advanced glycation end products (age)
|
US20050191653A1
(en)
|
2003-11-03 |
2005-09-01 |
Freier Susan M. |
Modulation of SGLT2 expression
|
US7915227B2
(en)
*
|
2003-11-14 |
2011-03-29 |
Het Nederlands Kanker Instituut |
Pharmaceutical formulations employing short-chain sphingolipids and their use
|
US20050129753A1
(en)
*
|
2003-11-14 |
2005-06-16 |
Gabizon Alberto A. |
Method for drug loading in liposomes
|
ES2472690T3
(es)
|
2003-11-17 |
2014-07-02 |
Genentech, Inc. |
Anticuerpo contra CD22 para el tratamiento de tumores de origen hematopoy�tico
|
CN1914226B
(zh)
*
|
2003-11-25 |
2012-02-01 |
达纳-法伯癌症研究院有限公司 |
SARS-CoV抗体及其使用方法
|
US7312320B2
(en)
|
2003-12-10 |
2007-12-25 |
Novimmune Sa |
Neutralizing antibodies and methods of use thereof
|
US9050378B2
(en)
*
|
2003-12-10 |
2015-06-09 |
Board Of Regents, The University Of Texas System |
N2S2 chelate-targeting ligand conjugates
|
EP2336178A1
(en)
|
2003-12-11 |
2011-06-22 |
Genentech, Inc. |
Methods and compositions for inhibiting C-Met dimerization and activation
|
KR20070001932A
(ko)
*
|
2003-12-23 |
2007-01-04 |
리나트 뉴로사이언스 코퍼레이션 |
작용물질 항 티알케이씨 항체 및 그의 사용 방법
|
HUE026132T2
(en)
|
2004-01-07 |
2016-05-30 |
Novartis Vaccines & Diagnostics Inc |
M-CSF-specific monoclonal antibody and its uses
|
KR20060103957A
(ko)
*
|
2004-01-15 |
2006-10-04 |
알자 코포레이션 |
치료제 전달용의 리포솜 조성물
|
EP1711606A2
(en)
|
2004-01-20 |
2006-10-18 |
Isis Pharmaceuticals, Inc. |
Modulation of glucocorticoid receptor expression
|
US7468431B2
(en)
|
2004-01-22 |
2008-12-23 |
Isis Pharmaceuticals, Inc. |
Modulation of eIF4E-BP2 expression
|
EP1727556A2
(en)
*
|
2004-02-17 |
2006-12-06 |
University Of South Florida |
Materials and methods for treatment of inflammatory and cell proliferation disorders
|
US20050181035A1
(en)
*
|
2004-02-17 |
2005-08-18 |
Dow Steven W. |
Systemic immune activation method using non CpG nucleic acids
|
EP2168986A3
(en)
|
2004-02-19 |
2010-07-28 |
Genentech, Inc. |
CDR-repaired antibodies
|
US8784881B2
(en)
|
2004-03-05 |
2014-07-22 |
Board Of Regents, The University Of Texas System |
Liposomal curcumin for treatment of diseases
|
US8569474B2
(en)
|
2004-03-09 |
2013-10-29 |
Isis Pharmaceuticals, Inc. |
Double stranded constructs comprising one or more short strands hybridized to a longer strand
|
EP2899278A1
(en)
*
|
2004-03-12 |
2015-07-29 |
Alnylam Pharmaceuticals Inc. |
iRNA agents targeting VEGF
|
US8790919B2
(en)
|
2004-03-15 |
2014-07-29 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for optimizing cleavage of RNA by RNase H
|
EP1579850A3
(en)
*
|
2004-03-15 |
2009-12-16 |
Nipro Corporation |
A pharmaceutical composition containing liposomes for treating a cancer
|
WO2005089448A2
(en)
*
|
2004-03-18 |
2005-09-29 |
Transave, Inc. |
Administration of cisplatin by inhalation
|
US20070065522A1
(en)
*
|
2004-03-18 |
2007-03-22 |
Transave, Inc. |
Administration of high potency platinum compound formulations by inhalation
|
JP4833836B2
(ja)
*
|
2004-03-26 |
2011-12-07 |
テルモ株式会社 |
リポソーム製剤
|
DK1730280T3
(en)
*
|
2004-03-26 |
2019-02-04 |
Curis Inc |
RNA interference modulators for hedgehog signaling and applications thereof
|
US20050244869A1
(en)
*
|
2004-04-05 |
2005-11-03 |
Brown-Driver Vickie L |
Modulation of transthyretin expression
|
US7794713B2
(en)
|
2004-04-07 |
2010-09-14 |
Lpath, Inc. |
Compositions and methods for the treatment and prevention of hyperproliferative diseases
|
NZ549990A
(en)
|
2004-04-07 |
2009-08-28 |
Rinat Neuroscience Copr |
Methods for treating bone cancer pain by administering a nerve growth factor antagonist
|
RU2006140374A
(ru)
*
|
2004-04-16 |
2008-05-27 |
Дженентек, Инк. (Us) |
Лечение нарушений
|
US20150017671A1
(en)
|
2004-04-16 |
2015-01-15 |
Yaping Shou |
Methods for detecting lp-pla2 activity and inhibition of lp-pla2 activity
|
US8658203B2
(en)
|
2004-05-03 |
2014-02-25 |
Merrimack Pharmaceuticals, Inc. |
Liposomes useful for drug delivery to the brain
|
WO2005107712A1
(en)
|
2004-05-03 |
2005-11-17 |
Hermes Biosciences, Inc. |
Liposomes useful for drug delivery
|
EP1761540B1
(en)
*
|
2004-05-13 |
2016-09-28 |
Icos Corporation |
Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
|
CA2566559C
(en)
*
|
2004-05-17 |
2014-05-06 |
Inex Pharmaceuticals Corporation |
Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof
|
EP1789453A2
(en)
*
|
2004-05-18 |
2007-05-30 |
Genentech, Inc. |
M13 virus major coat protein variants for c-terminal and bi-terminal display of a heterologous protein
|
US20050260260A1
(en)
*
|
2004-05-19 |
2005-11-24 |
Edward Kisak |
Liposome compositions for the delivery of macromolecules
|
US20060034906A1
(en)
*
|
2004-05-21 |
2006-02-16 |
Transave, Inc. |
Treatment of lung diseases and pre-lung disease conditions
|
EP1755609A1
(en)
*
|
2004-05-25 |
2007-02-28 |
Icos Corporation |
Methods for treating and/or preventing aberrant proliferation of hematopoietic cells
|
CA2567437A1
(en)
*
|
2004-05-25 |
2005-12-08 |
Metabolex, Inc. |
Substituted triazoles as modulators of ppar and methods of their preparation
|
JP2008500358A
(ja)
*
|
2004-05-25 |
2008-01-10 |
メタボレックス インコーポレーティッド |
Pparのモジュレーターとしての、二環式の置換されたトリアゾール、およびこれらの調製方法
|
JP5266492B2
(ja)
*
|
2004-05-28 |
2013-08-21 |
ヒューマン バイオモレキュラル リサーチ インスティテュート |
代謝安定性鎮痛薬、疼痛薬物療法及び他の物質の合成
|
JP2008501693A
(ja)
*
|
2004-06-03 |
2008-01-24 |
アイシス ファーマシューティカルズ、インク. |
遺伝子調節で使用するための個別に調節された鎖を有する二本鎖組成物
|
US20080261904A1
(en)
*
|
2004-06-03 |
2008-10-23 |
Balkrishen Bhat |
Chimeric Gapped Oligomeric Compounds
|
US8394947B2
(en)
|
2004-06-03 |
2013-03-12 |
Isis Pharmaceuticals, Inc. |
Positionally modified siRNA constructs
|
US20090048192A1
(en)
*
|
2004-06-03 |
2009-02-19 |
Isis Pharmaceuticals, Inc. |
Double Strand Compositions Comprising Differentially Modified Strands for Use in Gene Modulation
|
AU2005249566B2
(en)
|
2004-06-04 |
2010-11-11 |
Genentech, Inc. |
Method for treating multiple sclerosis
|
ATE536418T1
(de)
*
|
2004-06-07 |
2011-12-15 |
Protiva Biotherapeutics Inc |
Lipidverkapselte interferenz-rna
|
EP1781593B1
(en)
|
2004-06-07 |
2011-12-14 |
Protiva Biotherapeutics Inc. |
Cationic lipids and methods of use
|
CA2579756C
(en)
*
|
2004-06-19 |
2013-04-30 |
Human Biomolecular Research Institute |
Modulators of central nervous system neurotransmitters
|
EP1766077B1
(en)
|
2004-06-21 |
2012-03-28 |
The Board Of Trustees Of The Leland Stanford Junior University |
Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder
|
CA2572439A1
(en)
|
2004-07-02 |
2006-01-12 |
Protiva Biotherapeutics, Inc. |
Immunostimulatory sirna molecules and uses therefor
|
US20060019893A1
(en)
*
|
2004-07-02 |
2006-01-26 |
Genentech, Inc. |
Factor VIIa variants
|
JP2008505928A
(ja)
*
|
2004-07-08 |
2008-02-28 |
アムジェン インコーポレーテッド |
治療用ペプチド
|
US20090156471A1
(en)
*
|
2004-07-15 |
2009-06-18 |
Ramot At Tel Aviv University Ltd. |
Use of anti-amyloid agents for treating and typing pathogen infections
|
AU2005272993B2
(en)
|
2004-07-15 |
2010-02-11 |
Xencor, Inc |
Optimized Fc variants
|
WO2006007712A1
(en)
*
|
2004-07-19 |
2006-01-26 |
Protiva Biotherapeutics, Inc. |
Methods comprising polyethylene glycol-lipid conjugates for delivery of therapeutic agents
|
CA2580313C
(en)
*
|
2004-07-19 |
2016-03-15 |
Biocon Limited |
Insulin-oligomer conjugates, formulations and uses thereof
|
ATE456579T1
(de)
|
2004-07-20 |
2010-02-15 |
Genentech Inc |
Angiopoietin-like 4 protein hemmer kombinationen und deren verwendung
|
WO2006014928A1
(en)
|
2004-07-26 |
2006-02-09 |
Genentech, Inc. |
Methods and compositions for modulating hepatocyte growth factor activation
|
SG190665A1
(en)
*
|
2004-07-30 |
2013-06-28 |
Rinat Neuroscience Corp |
Antibodies directed against amyloid-beta peptide and methods using same
|
EP1781310B1
(en)
|
2004-08-02 |
2015-10-14 |
Ramot at Tel Aviv University Ltd. |
Articles of peptide nanostructures and method of forming the same
|
US9132116B2
(en)
*
|
2004-08-02 |
2015-09-15 |
Willowcroft Pharm Inc. |
Mast cell stabilizers to prevent or treat laminitis
|
CA2576422C
(en)
|
2004-08-17 |
2013-10-29 |
Tyco Healthcare Group Lp |
Anti-adhesion barrier
|
JP2006056807A
(ja)
*
|
2004-08-18 |
2006-03-02 |
Konica Minolta Medical & Graphic Inc |
光線力学療法製剤
|
ATE539745T1
(de)
|
2004-08-19 |
2012-01-15 |
Univ Tel Aviv Future Tech Dev |
Zusammensetzungen zur behandlung von amyloid- assoziierten erkrankungen
|
JP4715133B2
(ja)
*
|
2004-08-26 |
2011-07-06 |
コニカミノルタエムジー株式会社 |
抗腫瘍リポソーム製剤およびその製造方法
|
JP2006069929A
(ja)
*
|
2004-08-31 |
2006-03-16 |
Konica Minolta Medical & Graphic Inc |
真菌症治療製剤およびその製造方法
|
US7884086B2
(en)
|
2004-09-08 |
2011-02-08 |
Isis Pharmaceuticals, Inc. |
Conjugates for use in hepatocyte free uptake assays
|
US7786086B2
(en)
|
2004-09-08 |
2010-08-31 |
Ramot At Tel-Aviv University Ltd. |
Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same
|
US20080063702A1
(en)
*
|
2004-09-09 |
2008-03-13 |
Yechezkel Barenholz |
Liposomal Formulations Comprising an Amphipathic Weak Base Like Tempamine for Treatment of Neurodegenerative Conditions
|
WO2006027786A2
(en)
*
|
2004-09-09 |
2006-03-16 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Use of liposomal glucocorticoids for treating inflammatory states
|
US6998028B1
(en)
*
|
2004-09-24 |
2006-02-14 |
Superpower, Inc. |
Methods for forming superconducting conductors
|
EP1797127B1
(en)
*
|
2004-09-24 |
2017-06-14 |
Amgen Inc. |
Modified fc molecules
|
US8435948B2
(en)
|
2004-09-29 |
2013-05-07 |
Mount Sinai School Of Medicine Of New York University |
Methods for inhibiting osteoclastic bone resorption and bone loss comprising administration of an anti-FSH or anti-FSHR antibody
|
JP5101288B2
(ja)
|
2004-10-05 |
2012-12-19 |
カリフォルニア インスティテュート オブ テクノロジー |
アプタマー調節される核酸及びその利用
|
KR20070100228A
(ko)
|
2004-10-05 |
2007-10-10 |
제넨테크, 인크. |
혈관염의 치료 방법
|
WO2006042237A2
(en)
|
2004-10-06 |
2006-04-20 |
Mayo Foundation For Medical Education And Research |
B7-h1 and methods of diagnosis, prognosis, and treatment of cancer
|
TW200612993A
(en)
*
|
2004-10-08 |
2006-05-01 |
Alza Corp |
Lipopolymer conjugates
|
US7985417B2
(en)
*
|
2004-10-08 |
2011-07-26 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Method of lipid structure preparation
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
UA87877C2
(en)
*
|
2004-10-26 |
2009-08-25 |
Фарма Мар С.А., Сосьедад Униперсональ |
Pegylated liposomal doxorubicin in combination with ecteinescidin 743
|
JP2008518951A
(ja)
*
|
2004-10-28 |
2008-06-05 |
アルザ コーポレイション |
凍結乾燥リポソーム配合物及び方法
|
PT1658848E
(pt)
|
2004-10-29 |
2007-11-05 |
Pharma Mar Sa |
Formulações contendo ecteinascidina e um dissacarídeo
|
WO2006052767A2
(en)
|
2004-11-05 |
2006-05-18 |
Inex Pharmaceuticals Corporation |
Compositions and methods for stabilizing liposomal camptothecin formulations
|
TW200618820A
(en)
*
|
2004-11-05 |
2006-06-16 |
Alza Corp |
Liposome formulations of boronic acid compounds
|
WO2006055352A2
(en)
*
|
2004-11-08 |
2006-05-26 |
Transave, Inc. |
Methods of treating cancer with lipid-based platinum compound formulations administered intraperitoneally
|
US20090005292A1
(en)
*
|
2004-11-11 |
2009-01-01 |
Affymax, Inc. |
Novel Peptides that Bind to the Erythropoietin Receptor
|
AU2005303389A1
(en)
*
|
2004-11-15 |
2006-05-18 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Combination therapy associating preferably a ceramide with a cytotoxic drug
|
WO2006053430A1
(en)
*
|
2004-11-17 |
2006-05-26 |
Protiva Biotherapeutics, Inc. |
Sirna silencing of apolipoprotein b
|
US20070298094A1
(en)
*
|
2004-11-18 |
2007-12-27 |
Terumo Kabushiki Kaisha |
Medicinal Composition, Preparation and Combined Preparation
|
WO2006066158A2
(en)
*
|
2004-12-14 |
2006-06-22 |
Alnylam Pharmaceuticals, Inc. |
Rnai modulation of mll-af4 and uses thereof
|
DE602006013275D1
(de)
|
2005-01-07 |
2010-05-12 |
Diadexus Inc |
Ovr110-antikörperzusammensetzungen und verwendungsverfahren dafür
|
WO2006076471A2
(en)
*
|
2005-01-12 |
2006-07-20 |
Nobex Corporation |
Bnp conjugates and methods of use
|
CN101141981A
(zh)
|
2005-01-21 |
2008-03-12 |
健泰科生物技术公司 |
Her抗体的固定剂量给药
|
EP1842585A4
(en)
*
|
2005-01-28 |
2013-05-29 |
Kyowa Hakko Kirin Co Ltd |
PROCESS FOR PRODUCING A FINE PARTICLE WHOSE SURFACE IS MODIFIED BY A WATER SOLUBLE SUBSTANCE
|
US20090028889A1
(en)
|
2005-01-31 |
2009-01-29 |
Vaxinnate Corporation |
Novel Polypeptide Ligands For Toll-Like Receptor 2 (TLR2)
|
US8029783B2
(en)
*
|
2005-02-02 |
2011-10-04 |
Genentech, Inc. |
DR5 antibodies and articles of manufacture containing same
|
AU2006213686A1
(en)
|
2005-02-09 |
2006-08-17 |
Avi Bio Pharma, Inc. |
Antisense composition and method for treating muscle atrophy
|
DK1853718T3
(en)
|
2005-02-15 |
2015-11-09 |
Univ Duke |
ANTI-CD19 ANTIBODIES AND THEIR USE IN ONCOLOGY
|
AU2006214190A1
(en)
*
|
2005-02-17 |
2006-08-24 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
US8329178B2
(en)
|
2005-02-18 |
2012-12-11 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against CXCR4 and methods of use thereof
|
EP2382996B1
(en)
|
2005-02-18 |
2015-01-14 |
The University of Tokushima |
Lipid film structure containing a polyoxyalkylene chain-containing lipid derivative.
|
EP2399605A1
(en)
|
2005-02-23 |
2011-12-28 |
Genentech, Inc. |
Extending time to disease progression or survival in cancer patients
|
TW200714289A
(en)
*
|
2005-02-28 |
2007-04-16 |
Genentech Inc |
Treatment of bone disorders
|
TW200642695A
(en)
*
|
2005-03-08 |
2006-12-16 |
Genentech Inc |
Methods for identifying tumors responsive to treatment with her dimerization inhibitors (HDIs)
|
JP2006248978A
(ja)
*
|
2005-03-10 |
2006-09-21 |
Mebiopharm Co Ltd |
新規なリポソーム製剤
|
RU2007137489A
(ru)
|
2005-03-10 |
2009-04-20 |
Дженентек, Инк. (Us) |
Способы и композиции для модуляции целостности сосудов
|
US20070065359A1
(en)
*
|
2005-03-14 |
2007-03-22 |
Shiladitya Sengupta |
Nanocells for diagnosis and treatment of diseases and disorders
|
EP1865778A4
(en)
|
2005-03-21 |
2010-12-08 |
Metabolex Inc |
METHOD FOR AVOIDING OEDEM IN THE TREATMENT OF METABOLISM DISORDER, INFLAMMATORY DISEASES AND CARDIOVASCULAR DISEASES
|
CN1840193B
(zh)
*
|
2005-03-29 |
2010-05-12 |
中国科学院生物物理研究所 |
聚乙二醇化磷脂包载的蒽环类抗肿瘤抗生素的纳米胶束制剂
|
JP2008537551A
(ja)
|
2005-03-31 |
2008-09-18 |
カランド ファーマシューティカルズ, インコーポレイテッド |
リボヌクレオチドレダクターゼサブユニット2の阻害剤およびその使用
|
UY29504A1
(es)
|
2005-04-29 |
2006-10-31 |
Rinat Neuroscience Corp |
Anticuerpos dirigidos contra el péptido amiloide beta y métodos que utilizan los mismos.
|
WO2006121852A2
(en)
|
2005-05-05 |
2006-11-16 |
Duke University |
Anti-cd19 antibody therapy for autoimmune disease
|
ES2561628T3
(es)
|
2005-05-06 |
2016-02-29 |
Zymogenetics, Inc. |
Anticuerpos monoclonales IL-31 y métodos de uso
|
NZ581779A
(en)
|
2005-05-17 |
2011-09-30 |
Univ Connecticut |
Composition and methods for immunomodulation in an organism comprising interleukin-15 polypeptide and interleukin-15 receptor subunit A polypeptide complex
|
US8324159B2
(en)
*
|
2005-06-03 |
2012-12-04 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
US7550433B2
(en)
|
2005-06-03 |
2009-06-23 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
US7919461B2
(en)
*
|
2005-06-03 |
2011-04-05 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
NZ563341A
(en)
|
2005-06-06 |
2009-10-30 |
Genentech Inc |
Methods for identifying agents that modulate a gene that encodes for a PRO1568 polypeptide
|
US20070014845A1
(en)
*
|
2005-07-01 |
2007-01-18 |
Yuanpeng Zhang |
Liposomal delivery vehicle for hydrophobic drugs
|
CA2615615A1
(en)
|
2005-07-22 |
2007-02-01 |
Y's Therapeutics Co., Ltd. |
Anti-cd26 antibodies and methods of use thereof
|
ES2538036T3
(es)
*
|
2005-07-28 |
2015-06-16 |
Novartis Ag |
Uso de anticuerpo a M-CSF
|
WO2007016285A2
(en)
*
|
2005-07-28 |
2007-02-08 |
Novartis Ag |
M-csf specific monoclonal antibody and uses thereof
|
US20070055200A1
(en)
|
2005-08-10 |
2007-03-08 |
Gilbert Scott J |
Needle-free jet injection drug delivery device
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
JP2009504183A
(ja)
|
2005-08-15 |
2009-02-05 |
ジェネンテック・インコーポレーテッド |
遺伝子破壊、それに関連する組成物および方法
|
US20070054873A1
(en)
*
|
2005-08-26 |
2007-03-08 |
Protiva Biotherapeutics, Inc. |
Glucocorticoid modulation of nucleic acid-mediated immune stimulation
|
US7700567B2
(en)
|
2005-09-29 |
2010-04-20 |
Supergen, Inc. |
Oligonucleotide analogues incorporating 5-aza-cytosine therein
|
EP1973928A2
(en)
*
|
2005-10-11 |
2008-10-01 |
Ramot at Tel-Aviv University Ltd. |
Self-assembled fmoc-ff hydrogels
|
US7875602B2
(en)
*
|
2005-10-21 |
2011-01-25 |
Sutter West Bay Hospitals |
Camptothecin derivatives as chemoradiosensitizing agents
|
TW200732350A
(en)
|
2005-10-21 |
2007-09-01 |
Amgen Inc |
Methods for generating monovalent IgG
|
GB0522082D0
(en)
|
2005-10-31 |
2005-12-07 |
Pharma Mar Sa |
Formulations
|
PT1978993T
(pt)
|
2005-10-31 |
2017-03-17 |
Oncomed Pharm Inc |
Composições e métodos para diagnóstico e tratamento do cancro com base em recetores fzd humanos
|
EP2202239A1
(en)
|
2005-11-01 |
2010-06-30 |
Alnylam Pharmaceuticals Inc. |
RNAI inhibition of influenza virus replication
|
CA2628300C
(en)
*
|
2005-11-02 |
2018-04-17 |
Protiva Biotherapeutics, Inc. |
Modified sirna molecules and uses thereof
|
US7879212B2
(en)
*
|
2005-11-03 |
2011-02-01 |
Ramot At Tel-Aviv University Ltd. |
Peptide nanostructure-coated electrodes
|
DE102005053066A1
(de)
|
2005-11-04 |
2007-05-10 |
Basf Ag |
Verwendung von Copolymeren als Solubilisatoren für in Wasser schwerlöslichen Verbindungen
|
US20070190180A1
(en)
*
|
2005-11-08 |
2007-08-16 |
Pilkiewicz Frank G |
Methods of treating cancer with high potency lipid-based platinum compound formulations administered intravenously
|
WO2007056264A2
(en)
*
|
2005-11-08 |
2007-05-18 |
Transave, Inc. |
Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
|
US9107824B2
(en)
|
2005-11-08 |
2015-08-18 |
Insmed Incorporated |
Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
|
US20070190181A1
(en)
*
|
2005-11-08 |
2007-08-16 |
Pilkiewicz Frank G |
Methods of treating cancer with lipid-based platinum compound forumulations administered intravenously
|
US20090019557A1
(en)
|
2005-11-12 |
2009-01-15 |
Huda Akil |
Fgf2-related methods for diagnosing and treating depression
|
TW200736277A
(en)
|
2005-11-14 |
2007-10-01 |
Amgen Inc |
RANKL antibody-PTH/PTHrP chimeric molecules
|
EP3069731A1
(en)
|
2005-11-14 |
2016-09-21 |
Labrys Biologics Inc. |
Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
|
MY149159A
(en)
|
2005-11-15 |
2013-07-31 |
Hoffmann La Roche |
Method for treating joint damage
|
CA2629715C
(en)
|
2005-11-18 |
2016-05-03 |
Glenmark Pharmaceuticals S.A. |
Anti-alpha2 integrin antibodies and their uses
|
JP2009516710A
(ja)
|
2005-11-21 |
2009-04-23 |
アイシス ファーマシューティカルズ, インコーポレーテッド |
eIF4E−BP2の発現のモジュレート
|
WO2007081608A2
(en)
|
2005-11-21 |
2007-07-19 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
US20070122350A1
(en)
*
|
2005-11-30 |
2007-05-31 |
Transave, Inc. |
Safe and effective methods of administering therapeutic agents
|
US8466263B2
(en)
*
|
2005-12-02 |
2013-06-18 |
Dana-Farber Cancer Institute, Inc. |
Carbonic anhydrase IX (G250) anitbodies
|
WO2007126439A2
(en)
|
2005-12-02 |
2007-11-08 |
Genentech, Inc. |
Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r
|
CN101365424A
(zh)
*
|
2005-12-08 |
2009-02-11 |
耶路撒冷希伯来大学伊森姆研究发展公司 |
通过超声辐射改变脂质体组成的方法
|
JP2009523119A
(ja)
*
|
2005-12-09 |
2009-06-18 |
ビーエーエスエフ ソシエタス・ヨーロピア |
水に溶けにくい化合物のための可溶化剤としてのポリビニルラクタム−ポリオキシアルキレンブロックコポリマーの使用
|
US9149543B2
(en)
|
2005-12-15 |
2015-10-06 |
The Trustees Of The University Of Pennsylvania |
Methods and models for rapid, widespread delivery of genetic material to the CNS using non-viral, cationic lipid-mediated vectors
|
WO2007082144A2
(en)
*
|
2006-01-05 |
2007-07-19 |
Mayo Foundation For Medical Education And Research |
B7-h1 and survivin in cancer
|
WO2007082154A2
(en)
*
|
2006-01-05 |
2007-07-19 |
Mayo Foundation For Medical Education And Research |
B7-h1 and b7-h4 in cancer
|
EP1984024A2
(en)
*
|
2006-01-05 |
2008-10-29 |
Novartis AG |
Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
|
CA2638908C
(en)
|
2006-01-26 |
2021-04-27 |
Susan M. Freier |
Compositions and their uses directed to huntingtin
|
EP2264060B1
(en)
|
2006-01-26 |
2014-04-23 |
Recopharma AB |
Compositions and methods for inhibiting viral adhesion
|
US7829097B2
(en)
*
|
2006-02-06 |
2010-11-09 |
University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Use of HMGB1 for protection against ischemia reperfusion injury
|
US20080311107A1
(en)
|
2006-02-17 |
2008-12-18 |
Genetech, Inc. |
Novel Gene Disruptions, Compositions and Methods Relating Thereto
|
EP2650306A1
(en)
|
2006-03-06 |
2013-10-16 |
Aeres Biomedical Limited |
Humanized Anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
US20070218116A1
(en)
*
|
2006-03-14 |
2007-09-20 |
Schwendener Reto A |
Compositions and methods for the treatment of tumors and tumor metastases
|
US9119782B2
(en)
*
|
2006-03-20 |
2015-09-01 |
Mary P. McCourt |
Drug delivery means
|
ES2544957T3
(es)
|
2006-03-21 |
2015-09-07 |
Genentech, Inc. |
Terapia combinada que implica antagonistas alfa5beta1
|
EP2389951A1
(en)
|
2006-03-23 |
2011-11-30 |
Novartis AG |
Anti-tumor cell antigen antibody therapeutics
|
NZ571568A
(en)
|
2006-03-31 |
2010-11-26 |
Alnylam Pharmaceuticals Inc |
Double-stranded RNA molecule compositions and methods for inhibiting expression of Eg5 gene
|
WO2007126455A2
(en)
|
2006-04-05 |
2007-11-08 |
Genentech, Inc. |
Method for using boc/cdo to modulate hedgehog signaling
|
US8758723B2
(en)
|
2006-04-19 |
2014-06-24 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for cellular imaging and therapy
|
US20090288176A1
(en)
|
2006-04-19 |
2009-11-19 |
Genentech, Inc. |
Novel Gene Disruptions, Compositions and Methods Relating Thereto
|
WO2007124361A2
(en)
*
|
2006-04-20 |
2007-11-01 |
Mayo Foundation For Medical Education And Research |
Soluble b7-h1
|
AU2007242061B2
(en)
|
2006-04-21 |
2012-11-29 |
Intervet International B.V. |
Pestivirus species
|
WO2007127919A2
(en)
|
2006-04-28 |
2007-11-08 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a gene from the jc virus
|
US8298818B2
(en)
*
|
2006-04-28 |
2012-10-30 |
University Of Florida Research Foundation, Inc. |
Self-complementary adeno-associated virus having a truncated CMV-chicken β-actin promoter
|
WO2008018932A2
(en)
*
|
2006-05-01 |
2008-02-14 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method and use of nano-scale devices for reduction of tissue injury in ischemic and reperfusion injury
|
EP2013344B1
(en)
*
|
2006-05-03 |
2012-08-29 |
Baltic Technology Development, Ltd. |
Antisense agents combining strongly bound base - modified oligonucleotide and artificial nuclease
|
WO2007133627A2
(en)
*
|
2006-05-10 |
2007-11-22 |
Alza Corporation |
Method for making liposomes conjugated with temperature-sensitive ligands
|
US20070281034A1
(en)
*
|
2006-05-15 |
2007-12-06 |
Kirpotin Dmitri B |
Magnetic microparticles comprising organic substances
|
US20080014205A1
(en)
|
2006-05-15 |
2008-01-17 |
Lawrence Horowitz |
Neutralizing Antibodies to Influenza Viruses
|
EP2392583A1
(en)
|
2006-05-19 |
2011-12-07 |
Alnylam Europe AG. |
RNAi modulation of Aha and therapeutic uses thereof
|
WO2007137163A2
(en)
*
|
2006-05-19 |
2007-11-29 |
Georgia Tech Research Corporation |
Abc transporter ligand
|
CA2653451C
(en)
*
|
2006-05-22 |
2015-12-29 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of ikk-b gene
|
EP2023938A4
(en)
*
|
2006-05-23 |
2010-11-10 |
Isis Pharmaceuticals Inc |
MODULATION OF THE EXPRESSION OF ChREBP
|
US8598333B2
(en)
*
|
2006-05-26 |
2013-12-03 |
Alnylam Pharmaceuticals, Inc. |
SiRNA silencing of genes expressed in cancer
|
US7862812B2
(en)
|
2006-05-31 |
2011-01-04 |
Lpath, Inc. |
Methods for decreasing immune response and treating immune conditions
|
US7915399B2
(en)
*
|
2006-06-09 |
2011-03-29 |
Protiva Biotherapeutics, Inc. |
Modified siRNA molecules and uses thereof
|
US7981425B2
(en)
|
2006-06-19 |
2011-07-19 |
Amgen Inc. |
Thrombopoietic compounds
|
WO2007149433A2
(en)
*
|
2006-06-19 |
2007-12-27 |
The Johns Hopkins University |
Tumor-specific delivery of therapeutic agents via liposomase
|
WO2008002591A2
(en)
|
2006-06-26 |
2008-01-03 |
Amgen Inc |
Methods for treating atherosclerosis
|
EP2029173B1
(en)
|
2006-06-26 |
2016-07-20 |
MacroGenics, Inc. |
Fc riib-specific antibodies and methods of use thereof
|
JP5072275B2
(ja)
|
2006-07-03 |
2012-11-14 |
テルモ株式会社 |
閉鎖小胞の分離方法、製剤の製造方法および評価方法
|
CN101511181B
(zh)
|
2006-07-11 |
2013-08-21 |
新泽西医科和牙科大学 |
蛋白、编码该蛋白的核酸和相关的应用方法
|
US8343539B2
(en)
|
2006-07-14 |
2013-01-01 |
Regents Of The University Of Minnesota |
Compounds that bind α5β1 integrin and methods of use
|
US8324158B2
(en)
*
|
2006-07-14 |
2012-12-04 |
Georgia Tech Research Corporation |
Methods for inhibiting CLC-2 channel with GATX2
|
ES2612383T3
(es)
|
2006-07-19 |
2017-05-16 |
The Trustees Of The University Of Pennsylvania |
WSX-1/IL-27 como una diana para respuestas antiinflamatorias
|
US8198253B2
(en)
|
2006-07-19 |
2012-06-12 |
Isis Pharmaceuticals, Inc. |
Compositions and their uses directed to HBXIP
|
JP4936312B2
(ja)
*
|
2006-07-20 |
2012-05-23 |
株式会社島津製作所 |
新規な両親媒性物質、それを用いた薬剤搬送システム及び分子イメージングシステム
|
WO2008013918A2
(en)
*
|
2006-07-26 |
2008-01-31 |
Myelin Repair Foundation, Inc. |
Cell cycle regulation and differentiation
|
EP2420252A1
(en)
*
|
2006-08-04 |
2012-02-22 |
Novartis AG |
EPHB3-specific antibody and uses thereof
|
EP2520935A3
(en)
|
2006-08-09 |
2013-02-13 |
Homestead Clinical Corporation |
Organ-specific proteins and methods of their use
|
ME01786B
(me)
|
2006-08-14 |
2014-09-20 |
Xencor Inc |
Optimizovana antitela usmerena na cd19
|
ME00588A
(en)
*
|
2006-08-18 |
2011-12-20 |
|
Prlr-specific antibody and uses thereof
|
EP2061900A2
(en)
|
2006-08-25 |
2009-05-27 |
Oncotherapy Science, Inc. |
Prognostic markers and therapeutic targets for lung cancer
|
CA2661782C
(en)
|
2006-08-28 |
2019-04-16 |
La Jolla Institute For Allergy And Immunology |
Antagonistic human light-specific human monoclonal antibodies
|
ZA200900957B
(en)
|
2006-08-29 |
2010-05-26 |
Genentech Inc |
Use of tenecteplase for treating acute ischemic stroke
|
CA2660175C
(en)
|
2006-09-01 |
2015-05-12 |
Zymogenetics, Inc. |
Variable region sequences of il-31 monoclonal antibodies and methods of use
|
CA2600220C
(en)
*
|
2006-09-07 |
2014-12-09 |
Canadian Blood Services |
Surface cross-linked lipidic particles, methods of production and uses therefor
|
WO2008042236A2
(en)
|
2006-09-29 |
2008-04-10 |
Oncomed Pharmaceuticals, Inc. |
Compositions and methods for diagnosing and treating cancer
|
KR101161923B1
(ko)
|
2006-10-03 |
2012-07-03 |
유니버시티 오브 메디신 앤드 덴티스트리 오브 뉴 저지 |
Atap 펩티드, 상기 펩티드를 엔코딩하는 핵산 및 이들과 관련된 사용 방법
|
US10925977B2
(en)
|
2006-10-05 |
2021-02-23 |
Ceil>Point, LLC |
Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
|
CA2667678A1
(en)
|
2006-10-25 |
2008-07-24 |
Amgen Inc. |
Toxin peptide therapeutic agents
|
JP5732182B2
(ja)
|
2006-10-27 |
2015-06-10 |
エルパス・インコーポレイテッドLpath, Inc. |
眼疾患と症状を処置するための組成物および方法
|
ES2524059T3
(es)
|
2006-10-27 |
2014-12-03 |
Lpath, Inc. |
Composiciones y procedimientos de unión a esfingosina-1-fosfato
|
US8158595B2
(en)
|
2006-11-09 |
2012-04-17 |
California Institute Of Technology |
Modular aptamer-regulated ribozymes
|
EP2078037A4
(en)
*
|
2006-11-10 |
2010-01-27 |
Dimerix Bioscience Pty Ltd |
HETERODIMERS / OLIGOMERS OF THE RECEPTOR FOR THE THYROTROPIN RELEASING HORMONE OF THE OREXIN RECEPTOR
|
EP2097422A4
(en)
*
|
2006-11-13 |
2010-04-14 |
Lilly Co Eli |
THIENOPYRIMIDINONE FOR THE TREATMENT OF INFLAMMATORY DISEASES AND CARCINOMAS
|
CA2670696A1
(en)
|
2006-11-27 |
2008-06-05 |
Diadexus, Inc. |
Ovr110 antibody compositions and methods of use
|
ES2435437T3
(es)
|
2006-12-07 |
2013-12-19 |
Novartis Ag |
Anticuerpos antagonistas contra Ephb3
|
EP1932517A3
(en)
*
|
2006-12-11 |
2008-07-16 |
Universiteit Utrecht Holding B.V. |
Liposomes containing a polyphenol derivative such as caffeic acid and a method of post-loading thereof
|
WO2008076964A1
(en)
*
|
2006-12-18 |
2008-06-26 |
The Johns Hopkins University |
Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of atp production
|
WO2008079982A2
(en)
|
2006-12-21 |
2008-07-03 |
Centocor, Inc. |
Liposome composition for targeting egfr receptor
|
WO2008079976A2
(en)
|
2006-12-21 |
2008-07-03 |
Centocor, Inc. |
Dimeric high affinity egfr constructs and uses thereof
|
WO2008079973A2
(en)
*
|
2006-12-21 |
2008-07-03 |
Centocor, Inc. |
Egfr binding peptides and uses thereof
|
EP2913341A1
(en)
|
2006-12-22 |
2015-09-02 |
University of Utah Research Foundation |
Method of detecting ocular diseases and pathologic conditions and treatment of same
|
US8440185B2
(en)
*
|
2006-12-26 |
2013-05-14 |
The Johns Hopkins University |
Compositions and methods for the treatment of immunologic disorders
|
US20090142342A1
(en)
*
|
2006-12-27 |
2009-06-04 |
Johns Hopkins University |
B7-h4 receptor agonist compositions and methods for treating inflammation and auto-immune diseases
|
US7989173B2
(en)
|
2006-12-27 |
2011-08-02 |
The Johns Hopkins University |
Detection and diagnosis of inflammatory disorders
|
CA2673659A1
(en)
*
|
2006-12-27 |
2008-07-10 |
The Johns Hopkins University |
Methods of detecting and diagnosing inflamatory responses and disorders by determining the level of soluble b7-h4
|
US7638541B2
(en)
|
2006-12-28 |
2009-12-29 |
Metabolex Inc. |
5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
|
WO2008086807A2
(en)
*
|
2007-01-19 |
2008-07-24 |
Exiqon A/S |
Mediated cellular delivery of lna oligonucleotides
|
US20100329664A1
(en)
*
|
2007-01-23 |
2010-12-30 |
Lim Dae-Soon |
Shutter device for camera
|
EP2114981B1
(en)
|
2007-01-29 |
2013-05-08 |
Isis Pharmaceuticals, Inc. |
Compounds and methods for modulating protein expression
|
WO2008094275A1
(en)
|
2007-01-30 |
2008-08-07 |
New York University |
Peptides for treatment of conditions associated with nitric oxide
|
ES2379413T3
(es)
|
2007-02-22 |
2012-04-25 |
Genentech, Inc. |
Procedimientos para detectar la enfermedad inflamatoria del intestino
|
WO2008109440A2
(en)
|
2007-03-02 |
2008-09-12 |
Genentech, Inc. |
Predicting response to a her dimerisation inhibitor based on low her3 expression
|
CA2681302C
(en)
*
|
2007-03-19 |
2013-07-23 |
Dhiraj Khattar |
Proliposomal and liposomal compositions of poorly water-soluble compounds
|
JP4510842B2
(ja)
*
|
2007-03-26 |
2010-07-28 |
キヤノン株式会社 |
ポリヒドロキシアルカノエート被覆リポソーム
|
US7759320B2
(en)
|
2007-03-29 |
2010-07-20 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a gene from the Ebola
|
SG194368A1
(en)
|
2007-05-04 |
2013-11-29 |
Technophage Investigacao E Desenvolvimento Em Biotecnologia Sa |
Engineered rabbit antibody variable domains and uses thereof
|
CN101861168B
(zh)
|
2007-05-07 |
2014-07-02 |
米迪缪尼有限公司 |
抗-icos抗体及其在治疗肿瘤、移植和自身免疫病中的应用
|
US20090175784A1
(en)
|
2007-05-11 |
2009-07-09 |
Joshua Goldstein |
Anti-Alpha V Immunoliposome Composition, Methods, and Uses
|
US20090163698A1
(en)
*
|
2007-05-11 |
2009-06-25 |
John Joseph Grigsby |
Method for Preparing Antibody Conjugates
|
WO2008141276A1
(en)
*
|
2007-05-11 |
2008-11-20 |
Centocor, Inc. |
Anti-alpha-v immunoliposome composition, methods and uses
|
EP2650018A3
(en)
|
2007-05-14 |
2014-09-03 |
The University of Chicago |
Antibody-LIGHT fusion products for cancer therapeutics
|
AU2008350535B2
(en)
|
2007-05-14 |
2013-08-22 |
Novimmune S.A. |
Fc receptor-binding polypeptides with modified effector functions
|
CA2687141C
(en)
|
2007-05-22 |
2014-04-01 |
Amgen Inc. |
Compositions and methods for producing bioactive fusion proteins
|
WO2008148023A2
(en)
*
|
2007-05-23 |
2008-12-04 |
Medical College Of Georgia Research Institute, Inc. |
Compositions and methods for treating neurological disorders
|
JP2010527618A
(ja)
|
2007-05-24 |
2010-08-19 |
アメリカ合衆国 |
ヌクレオシドサルベージ経路を通しての核内タンパク質伝達
|
US9163091B2
(en)
*
|
2007-05-30 |
2015-10-20 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
CA2693053C
(en)
|
2007-05-30 |
2021-01-05 |
Xencor, Inc. |
Methods and compositions for inhibiting cd32b expressing cells
|
US8158124B2
(en)
*
|
2007-05-30 |
2012-04-17 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
AR066984A1
(es)
|
2007-06-15 |
2009-09-23 |
Novartis Ag |
Inhibicion de la expresion de la subunidad alfa del canal epitelial de sodio (enac) por medio de arni (arn de interferencia)
|
TW200916094A
(en)
*
|
2007-06-27 |
2009-04-16 |
Poniard Pharmaceuticals Inc |
Stabilized picoplatin dosage form
|
WO2009029342A2
(en)
|
2007-07-13 |
2009-03-05 |
The Johns Hopkins University |
B7-dc variants
|
PT2176296E
(pt)
|
2007-07-16 |
2012-05-14 |
Genentech Inc |
Anticorpos e imunoconjugados anti-cd79b e métodos de utilização
|
US20090082217A1
(en)
*
|
2007-07-16 |
2009-03-26 |
California Institute Of Technology |
Selection of nucleic acid-based sensor domains within nucleic acid switch platform
|
JP2010533495A
(ja)
|
2007-07-16 |
2010-10-28 |
ジェネンテック, インコーポレイテッド |
ヒト化CD79b抗体およびイムノコンジュゲートならびにそれらの使用
|
BRPI0814294A2
(pt)
*
|
2007-07-19 |
2015-02-03 |
Metabolex Inc |
Agonistas de receptor heterocíclico ligado a n para o tratamento do diabetes e de desordens metabólicas.
|
WO2009013202A1
(de)
*
|
2007-07-26 |
2009-01-29 |
Basf Se |
Verfahren zur herstellung von durch pfropfpolymerisation in lösung erhaltenen copolymeren auf basis von polyethern in fester form
|
NZ582794A
(en)
|
2007-07-26 |
2012-09-28 |
Amgen Inc |
Modified lecithin-cholesterol acyltransferase enzymes
|
US7666973B2
(en)
|
2007-07-30 |
2010-02-23 |
Tyco Healthcare Group Lp |
Carbonate copolymers
|
CN101835490A
(zh)
|
2007-08-02 |
2010-09-15 |
阿雷斯托生物科学股份有限公司 |
Lox和loxl2抑制剂及其应用
|
US20110269942A1
(en)
*
|
2007-08-09 |
2011-11-03 |
Daiichi Sankyo Company, Limited |
Antibodies modified with hydrophobic molecule
|
US8268958B2
(en)
|
2007-08-15 |
2012-09-18 |
Tyco Healthcare Group Ip |
Phospholipid copolymers
|
US20090048423A1
(en)
*
|
2007-08-15 |
2009-02-19 |
Tyco Healthcare Group Lp |
Phospholipid Copolymers
|
US8367815B2
(en)
*
|
2007-08-28 |
2013-02-05 |
California Institute Of Technology |
Modular polynucleotides for ligand-controlled regulatory systems
|
US20120165387A1
(en)
|
2007-08-28 |
2012-06-28 |
Smolke Christina D |
General composition framework for ligand-controlled RNA regulatory systems
|
WO2009033130A1
(en)
*
|
2007-09-07 |
2009-03-12 |
Gencia Corporation |
Mitochondrial compositions and uses thereof
|
US8865667B2
(en)
*
|
2007-09-12 |
2014-10-21 |
California Institute Of Technology |
Higher-order cellular information processing devices
|
CA2700378A1
(en)
*
|
2007-09-21 |
2009-03-29 |
Cytimmune Sciences, Inc. |
Nanotherapeutic colloidal metal compositions and methods
|
US20110014118A1
(en)
*
|
2007-09-21 |
2011-01-20 |
Lawrence Tamarkin |
Nanotherapeutic colloidal metal compositions and methods
|
CN101827613A
(zh)
*
|
2007-09-27 |
2010-09-08 |
免疫疫苗技术有限公司 |
在包括连续疏水相的载体中的脂质体在体内输送多核苷酸中的应用
|
WO2009040426A1
(en)
|
2007-09-28 |
2009-04-02 |
Universitätsspital Basel |
Immunoliposomes for treatment of cancer
|
AU2008307482B2
(en)
|
2007-10-02 |
2012-07-12 |
Amgen Inc. |
Increasing erythropoietin using nucleic acids hybridizable to micro-RNA and precursors thereof
|
US20100209452A1
(en)
*
|
2007-10-03 |
2010-08-19 |
Immunovaccine Technologies, Inc |
Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof
|
JP5868594B2
(ja)
*
|
2007-10-16 |
2016-02-24 |
バイオコン・リミテッドBiocon Limited |
経口投与可能な固形医薬組成物及びそのプロセス
|
US8361465B2
(en)
*
|
2007-10-26 |
2013-01-29 |
Lpath, Inc. |
Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
|
SI2219452T1
(sl)
|
2007-11-05 |
2016-03-31 |
Medimmune, Llc |
Postopki zdravljenja skleroderme
|
EP2217705A2
(en)
*
|
2007-11-05 |
2010-08-18 |
Baltic Technology Development, Ltd. |
Use of oligonucleotides with modified bases in hybridization of nucleic acids
|
MX2010005108A
(es)
|
2007-11-07 |
2010-05-27 |
Genentech Inc |
Composiciones y metodos para el tratamiento de trastornos microbianos.
|
US20110033476A1
(en)
*
|
2007-11-12 |
2011-02-10 |
Theraclone Sciences Inc. |
Compositions and methods for the therapy and diagnosis of influenza
|
WO2009064805A1
(en)
|
2007-11-12 |
2009-05-22 |
Spaltudaq Corporation |
Compositions and methods for the therapy and diagnosis of influenza
|
US8598165B2
(en)
*
|
2007-11-26 |
2013-12-03 |
University Of Kansas |
Morpholines as selective inhibitors of cytochrome P450 2A13
|
EP2222701B1
(en)
|
2007-12-06 |
2017-11-01 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against influenza virus and methods of use thereof
|
DK2796466T3
(en)
|
2007-12-07 |
2018-02-05 |
Zymogenetics Inc |
HUMANIZED ANTIBODY MOLECULE SPECIFIC TO IL-31
|
JP5530933B2
(ja)
|
2007-12-10 |
2014-06-25 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
第vii因子遺伝子発現阻害のための組成物及び方法
|
US9029524B2
(en)
*
|
2007-12-10 |
2015-05-12 |
California Institute Of Technology |
Signal activated RNA interference
|
CA2709135C
(en)
|
2007-12-17 |
2018-06-05 |
Pfizer Limited |
Treatment of interstitial cystitis
|
WO2009086514A1
(en)
|
2007-12-28 |
2009-07-09 |
Dana-Farber Cancer Institute, Inc. |
Humanized monoclonal antibodies and methods of use
|
WO2009086558A1
(en)
|
2008-01-02 |
2009-07-09 |
Tekmira Pharmaceuticals Corporation |
Improved compositions and methods for the delivery of nucleic acids
|
US20090181094A1
(en)
*
|
2008-01-15 |
2009-07-16 |
Eric Yueh-Lang Sheu |
Molecular Cage for Sustained Release Control of Pharmaceutical and Cosmetic Agents
|
AR070141A1
(es)
*
|
2008-01-23 |
2010-03-17 |
Glenmark Pharmaceuticals Sa |
Anticuerpos humanizados especificos para el factor von willebrand
|
TWI472339B
(zh)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至her2結構域ii之抗體及其酸性變異體的組合物
|
MY157403A
(en)
|
2008-01-31 |
2016-06-15 |
Genentech Inc |
Anti-cd79b antibodies and immunoconjugates and methods of use
|
WO2009111315A2
(en)
*
|
2008-02-29 |
2009-09-11 |
Mayo Foundation For Medical Education And Research |
Methods for reducing granulomatous inflammation
|
AU2009221775B2
(en)
*
|
2008-03-05 |
2015-05-07 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of Eg5 and VEGF genes
|
WO2009114560A2
(en)
|
2008-03-10 |
2009-09-17 |
Spaltudaq Corporation |
Compositions and methods for the therapy and diagnosis of cytomegalovirus
|
EP2105145A1
(en)
*
|
2008-03-27 |
2009-09-30 |
ETH Zürich |
Method for muscle-specific delivery lipid-conjugated oligonucleotides
|
AU2009228058A1
(en)
|
2008-03-28 |
2009-10-01 |
Sea Lane Biotechnologies, Llc |
Neutralizing molecules to viral antigens
|
CA2719507C
(en)
*
|
2008-03-31 |
2018-03-27 |
Metabolex, Inc. |
Oxymethylene aryl compounds and uses thereof
|
EP2283133A2
(en)
|
2008-04-04 |
2011-02-16 |
Calando Pharmaceuticals, Inc. |
Compositions and use of epas1 inhibitors
|
US20090258013A1
(en)
|
2008-04-09 |
2009-10-15 |
Genentech, Inc. |
Novel compositions and methods for the treatment of immune related diseases
|
EP2274437B1
(en)
|
2008-04-10 |
2015-12-23 |
Cell Signaling Technology, Inc. |
Compositions and methods for detecting egfr mutations in cancer
|
PL2279254T3
(pl)
|
2008-04-15 |
2017-11-30 |
Protiva Biotherapeutics Inc. |
Nowe preparaty lipidowe do dostarczania kwasów nukleinowych
|
US8324366B2
(en)
|
2008-04-29 |
2012-12-04 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for delivering RNAI using lipoproteins
|
JP2011523401A
(ja)
*
|
2008-04-29 |
2011-08-11 |
ワイス・エルエルシー |
炎症を治療するための方法
|
AU2009245358A1
(en)
*
|
2008-05-09 |
2009-11-12 |
Recopharma Ab |
Compositions and methods for inhibiting shiga toxin and shiga-like toxin
|
US20090280134A1
(en)
*
|
2008-05-09 |
2009-11-12 |
Recopharma Ab |
Compositions and methods for inhibiting toxin a from clostridium difficile
|
CA2723614C
(en)
|
2008-05-16 |
2015-07-14 |
Genentech, Inc. |
Use of biomarkers for assessing treatment of gastrointestinal inflammatory disorders with beta7 integrin antagonists
|
US8093018B2
(en)
|
2008-05-20 |
2012-01-10 |
Otsuka Pharmaceutical Co., Ltd. |
Antibody identifying an antigen-bound antibody and an antigen-unbound antibody, and method for preparing the same
|
WO2009140853A1
(en)
*
|
2008-05-23 |
2009-11-26 |
The University Of Hong Kong |
Combination therapy for the treatment of influenza
|
WO2009148121A1
(ja)
|
2008-06-05 |
2009-12-10 |
株式会社 島津製作所 |
新規な分子集合体、それを用いた分子イメージング用分子プローブ及び薬剤搬送システム用分子プローブ、並びに分子イメージングシステム及び薬剤搬送システム
|
CA2723918C
(en)
*
|
2008-06-05 |
2018-01-09 |
Immunovaccine Technologies Inc. |
Compositions comprising liposomes, an antigen, a polynucleotide and a carrier comprising a continuous phase of a hydrophobic substance
|
US8173621B2
(en)
*
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
WO2009150623A1
(en)
|
2008-06-13 |
2009-12-17 |
Pfizer Inc |
Treatment of chronic prostatitis
|
WO2009155431A1
(en)
*
|
2008-06-18 |
2009-12-23 |
University Of Louisville Research Foundation, Inc. |
Methods for targeted cancer treatment and detection
|
US20100003315A1
(en)
|
2008-07-02 |
2010-01-07 |
Willeford Kenneth L |
Method and Composition for the Treatment of Skin Conditions
|
PL2307051T3
(pl)
|
2008-07-08 |
2015-07-31 |
Oncomed Pharm Inc |
Środki wiążące i antagoniści Notch oraz sposoby ich zastosowania
|
KR101647334B1
(ko)
|
2008-07-10 |
2016-08-10 |
세리나 쎄라퓨틱스, 인코포레이티드 |
불활성 말단기를 가진 폴리옥사졸린, 보호된 개시기로부터 제조된 폴리옥사졸린 및 그와 관련된 화합물
|
US20100008900A1
(en)
*
|
2008-07-14 |
2010-01-14 |
The University Of Hong Kong |
Annexin ii compositions for treating or monitoring inflammation or immune-mediated disorders
|
US8815818B2
(en)
|
2008-07-18 |
2014-08-26 |
Rxi Pharmaceuticals Corporation |
Phagocytic cell delivery of RNAI
|
US20110237646A1
(en)
*
|
2008-08-07 |
2011-09-29 |
Isis Pharmaceuticals, Inc. |
Modulation of transthyretin expression for the treatment of cns related disorders
|
US8652843B2
(en)
|
2008-08-12 |
2014-02-18 |
Oncomed Pharmaceuticals, Inc. |
DDR1-binding agents and methods of use thereof
|
JP2012500197A
(ja)
|
2008-08-15 |
2012-01-05 |
ジョージタウン ユニバーシティー |
Rassf1a発現およびヒト癌細胞増殖の蛍光調節剤
|
WO2010021750A2
(en)
*
|
2008-08-21 |
2010-02-25 |
The Johns Hopkins University |
Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer
|
CN102149705B
(zh)
|
2008-08-22 |
2013-08-07 |
赛诺菲-安万特 |
作为肥大细胞类胰蛋白酶抑制剂的[4-(5-氨基甲基-2-氟苯基)-哌啶-1-基]-[7-氟-1-(2-甲氧基乙基)-4-三氟甲氧基-1h-吲哚-3-基]-甲酮
|
EP2328928A2
(en)
|
2008-08-25 |
2011-06-08 |
Dana-Farber Cancer Institute, Inc. |
Conserved influenza hemagglutinin epitope and antibodies thereto
|
EP2328919A2
(en)
*
|
2008-08-25 |
2011-06-08 |
Amplimmune, Inc. |
Pd-i antagonists and methods for treating infectious disease
|
WO2010027423A2
(en)
|
2008-08-25 |
2010-03-11 |
Amplimmune, Inc. |
Compositions of pd-1 antagonists and methods of use
|
KR101877698B1
(ko)
|
2008-08-25 |
2018-07-12 |
엑스칼리아드 파마슈티컬즈, 인코포레이티드 |
결합 조직 성장 인자에 대한 안티센스 올리고뉴클레오타이드 및 그의 용도
|
WO2010028054A1
(en)
|
2008-09-02 |
2010-03-11 |
Alnylam Europe Ag. |
Compositions and methods for inhibiting expression of mutant egfr gene
|
KR20110051245A
(ko)
|
2008-09-10 |
2011-05-17 |
제넨테크, 인크. |
안구 혈관신생의 억제 방법
|
TWI516501B
(zh)
|
2008-09-12 |
2016-01-11 |
禮納特神經系統科學公司 |
Pcsk9拮抗劑類
|
TW201014605A
(en)
|
2008-09-16 |
2010-04-16 |
Genentech Inc |
Methods for treating progressive multiple sclerosis
|
US8664189B2
(en)
|
2008-09-22 |
2014-03-04 |
Rxi Pharmaceuticals Corporation |
RNA interference in skin indications
|
CA2739170A1
(en)
|
2008-09-25 |
2010-04-01 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated compositions and methods for inhibiting expression of serum amyloid a gene
|
EP2350043B9
(en)
|
2008-10-09 |
2014-08-20 |
TEKMIRA Pharmaceuticals Corporation |
Improved amino lipids and methods for the delivery of nucleic acids
|
WO2010042823A1
(en)
|
2008-10-09 |
2010-04-15 |
Northeastern Universtiy |
Multifunctional self-assembling polymeric nanosystems
|
ES2656516T3
(es)
|
2008-10-20 |
2018-02-27 |
Alnylam Pharmaceuticals, Inc. |
Composiciones y métodos para inhibir la expresión de transtiretina
|
WO2010048207A2
(en)
*
|
2008-10-21 |
2010-04-29 |
Metabolex, Inc. |
Aryl gpr120 receptor agonists and uses thereof
|
WO2010046778A2
(en)
*
|
2008-10-21 |
2010-04-29 |
International Vaccine Institute |
Novel shigella frotein antigens and methods
|
US8871202B2
(en)
|
2008-10-24 |
2014-10-28 |
Lpath, Inc. |
Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
|
JP5775458B2
(ja)
*
|
2008-11-06 |
2015-09-09 |
グレンマーク ファーマシューティカルズ, エセ.アー. |
抗α2インテグリン抗体を使用する処置
|
KR102264822B1
(ko)
|
2008-11-10 |
2021-06-14 |
알닐람 파마슈티칼스 인코포레이티드 |
치료제 운반용 신규 지질 및 조성물
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
CA3092449A1
(en)
|
2008-11-13 |
2010-05-20 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
JP6041489B2
(ja)
|
2008-11-22 |
2016-12-07 |
ジェネンテック, インコーポレイテッド |
乳癌の治療のための化学療法と併用した抗vegf抗体の使用
|
US20110230399A1
(en)
*
|
2008-11-25 |
2011-09-22 |
Bowen Richard L |
Methods for Treating Obesity Related Disease
|
US20110160222A1
(en)
*
|
2008-11-26 |
2011-06-30 |
Metabolex, Inc. |
Modulators of glucose homeostasis for the treatment of diabetes and metabolic disorders
|
MX366774B
(es)
|
2008-12-04 |
2019-07-24 |
Curna Inc |
Uso de oligonucleótidos antisentido en la inhibición de transcrito antisentido natural para sirtuina 1.
|
KR101866152B1
(ko)
|
2008-12-04 |
2018-06-08 |
큐알엔에이, 인크. |
종양 억제 유전자에 대한 천연 안티센스 전사체의 억제에 의해 종양 억제 유전자 관련된 질환의 치료
|
RU2620970C2
(ru)
|
2008-12-04 |
2017-05-30 |
КьюРНА,Инк., |
Лечение связанных с эритропоэтином (еро) заболеваний путем ингибирования природного антисмыслового транскрипта к еро
|
AU2009324534B2
(en)
|
2008-12-10 |
2015-07-30 |
Alnylam Pharmaceuticals, Inc. |
GNAQ targeted dsRNA compositions and methods for inhibiting expression
|
US8628762B2
(en)
|
2008-12-10 |
2014-01-14 |
Icahn School Of Medicine At Mount Sinai |
T-helper cell type 17 lineage-specific adjuvants, compositions and methods
|
AR074760A1
(es)
|
2008-12-18 |
2011-02-09 |
Metabolex Inc |
Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
|
AR074776A1
(es)
|
2008-12-18 |
2011-02-09 |
Sanofi Aventis |
Metodo para tratar la degeneracion macular; modulando el sistema inmunitario del paciente
|
ES2484000T3
(es)
*
|
2008-12-22 |
2014-08-08 |
Creabilis S.A. |
Síntesis de conjugados poliméricos de compuestos de indolocarbazol
|
WO2010075249A2
(en)
|
2008-12-22 |
2010-07-01 |
Genentech, Inc. |
A method for treating rheumatoid arthritis with b-cell antagonists
|
KR20110104074A
(ko)
|
2008-12-23 |
2011-09-21 |
파마셋 인코포레이티드 |
퓨린 뉴클레오시드의 합성
|
PA8855601A1
(es)
*
|
2008-12-23 |
2010-07-27 |
|
Forformidatos de nucleósidos
|
US8551973B2
(en)
|
2008-12-23 |
2013-10-08 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
US9493774B2
(en)
|
2009-01-05 |
2016-11-15 |
Rxi Pharmaceuticals Corporation |
Inhibition of PCSK9 through RNAi
|
US20120101148A1
(en)
|
2009-01-29 |
2012-04-26 |
Alnylam Pharmaceuticals, Inc. |
lipid formulation
|
WO2010086828A2
(en)
|
2009-02-02 |
2010-08-05 |
Rinat Neuroscience Corporation |
Agonist anti-trkb monoclonal antibodies
|
WO2010090762A1
(en)
|
2009-02-04 |
2010-08-12 |
Rxi Pharmaceuticals Corporation |
Rna duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
|
ES2658626T3
(es)
|
2009-02-12 |
2018-03-12 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con el factor neurotrófico derivado de células gliales (GDNF) por inhibición de transcrito antisentido natural a GDNF
|
EP2396038B1
(en)
|
2009-02-12 |
2015-10-21 |
CuRNA, Inc. |
Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf
|
US8329882B2
(en)
|
2009-02-18 |
2012-12-11 |
California Institute Of Technology |
Genetic control of mammalian cells with synthetic RNA regulatory systems
|
WO2010099341A1
(en)
|
2009-02-26 |
2010-09-02 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of mig-12 gene
|
EP2403863B1
(en)
|
2009-03-02 |
2013-08-28 |
Alnylam Pharmaceuticals Inc. |
Nucleic acid chemical modifications
|
EP2963116B1
(en)
|
2009-03-04 |
2020-11-11 |
CuRNA, Inc. |
Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirt 1
|
EP2228059A1
(en)
|
2009-03-12 |
2010-09-15 |
Universitätsspital Basel |
Chemotherapeutic composition for the treatment of cancer
|
CN102421900B
(zh)
|
2009-03-12 |
2015-07-22 |
阿尔尼拉姆医药品有限公司 |
用于抑制Eg5和VEGF基因表达的脂质配制的组合物以及方法
|
ES2656290T3
(es)
|
2009-03-16 |
2018-02-26 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con el factor nuclear (derivado de eritroide 2) similar al 2 (NRF2) mediante inhibición del transcrito antisentido natural a NRF2
|
WO2010107740A2
(en)
|
2009-03-17 |
2010-09-23 |
Curna, Inc. |
Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1
|
SI3260136T1
(sl)
|
2009-03-17 |
2021-05-31 |
Theraclone Sciences, Inc. |
Humani imunodeficientni virus (HIV)-nevtralizirajoča protitelesa
|
MX2011009955A
(es)
|
2009-03-24 |
2011-11-18 |
Gilead Calistoga Llc |
Atropisomeros de derivados de 2-purinil-3-tolil-quinazolinona y metodos de uso.
|
CA2753988C
(en)
|
2009-03-25 |
2017-04-25 |
Genentech, Inc. |
Novel anti-.alpha.5.beta. integrin antibodies and uses thereof
|
AU2010232692C1
(en)
|
2009-04-01 |
2017-06-01 |
Genentech, Inc. |
Treatment of insulin-resistant disorders
|
JP6132548B2
(ja)
|
2009-04-01 |
2017-05-24 |
ジェネンテック, インコーポレイテッド |
抗FcRH5抗体および免疫接合体および使用方法
|
US9145555B2
(en)
|
2009-04-02 |
2015-09-29 |
California Institute Of Technology |
Integrated—ligand-responsive microRNAs
|
CN102458410A
(zh)
*
|
2009-04-20 |
2012-05-16 |
吉联亚·卡利斯托加有限责任公司 |
治疗实体瘤的方法
|
EP3524275A1
(en)
|
2009-04-22 |
2019-08-14 |
Massachusetts Institute Of Technology |
Innate immune supression enables repeated delivery of long rna molecules
|
SG175305A1
(en)
|
2009-04-23 |
2011-11-28 |
Theraclone Sciences Inc |
Granulocyte-macrophage colony-stimulating factor (gm-csf) neutralizing antibodies
|
EP2424567B1
(en)
*
|
2009-04-27 |
2018-11-21 |
OncoMed Pharmaceuticals, Inc. |
Method for making heteromultimeric molecules
|
EP2248903A1
(en)
|
2009-04-29 |
2010-11-10 |
Universitat Autònoma De Barcelona |
Methods and reagents for efficient and targeted gene transfer to monocytes and macrophages
|
US8524784B2
(en)
*
|
2009-04-30 |
2013-09-03 |
Intezyne Technologies, Incorporated |
Polymer micelles containing anthracylines for the treatment of cancer
|
EP2424359A4
(en)
|
2009-04-30 |
2014-01-15 |
Intezyne Technologies Inc |
POLYMIC MICELLES WITH ANTHRACYCLINES FOR THE TREATMENT OF CANCER
|
EP2424987B1
(en)
|
2009-05-01 |
2017-11-15 |
CuRNA, Inc. |
Treatment of hemoglobin (hbf/hbg) related diseases by inhibition of natural antisense transcript to hbf/hbg
|
CA3042927C
(en)
|
2009-05-05 |
2022-05-17 |
Arbutus Biopharma Corporation |
Lipid compositions for the delivery of therapeutic agents
|
JP5889783B2
(ja)
|
2009-05-05 |
2016-03-22 |
テクミラ ファーマシューティカルズ コーポレイションTekmira Pharmaceuticals Corporation |
免疫細胞へオリゴヌクレオチドを送達する方法
|
MX348013B
(es)
|
2009-05-05 |
2017-05-23 |
Novimmune Sa |
Anticuerpos anti il-17f y metodos de uso de los mismos.
|
US9155754B2
(en)
|
2009-05-06 |
2015-10-13 |
Curna, Inc. |
Treatment of ABCA1 gene related diseases by inhibition of a natural antisense transcript to ABCA1
|
US20120046236A1
(en)
|
2009-05-06 |
2012-02-23 |
Opko Curna Llc |
Treatment of tristetraproline (ttp) related diseases by inhibition of natural antisense transcript to ttp
|
KR101749356B1
(ko)
|
2009-05-18 |
2017-07-06 |
큐알엔에이, 인크. |
재편성 인자에 대한 천연 안티센스 전사체의 억제에 의한 재편성 인자 관련된 질환의 치료
|
US8858948B2
(en)
|
2009-05-20 |
2014-10-14 |
Theraclone Sciences, Inc. |
Compositions and methods for the therapy and diagnosis of influenza
|
TWI583692B
(zh)
|
2009-05-20 |
2017-05-21 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
EP2432499A2
(en)
|
2009-05-20 |
2012-03-28 |
Schering Corporation |
Modulation of pilr receptors to treat microbial infections
|
EP2432882B1
(en)
|
2009-05-22 |
2019-12-25 |
CuRNA, Inc. |
TREATMENT OF TRANSCRIPTION FACTOR E3 (TFE3) and INSULIN RECEPTOR SUBSTRATE 2 (IRS2) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO TFE3
|
WO2010138806A2
(en)
|
2009-05-28 |
2010-12-02 |
Curna, Inc. |
Treatment of antiviral gene related diseases by inhibition of natural antisense transcript to an antiviral gene
|
EA028860B1
(ru)
|
2009-06-10 |
2018-01-31 |
Арбутус Биофарма Корпорэйшн |
Улучшенная липидная композиция
|
US20120100206A1
(en)
|
2009-06-11 |
2012-04-26 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. |
Targeted liposomes comprising n-containing bisphosphonates and uses thereof
|
EP2443238B1
(en)
|
2009-06-16 |
2017-03-22 |
CuRNA, Inc. |
Treatment of paraoxonase 1 (pon1) related diseases by inhibition of natural antisense transcript to pon1
|
CA2765700C
(en)
|
2009-06-16 |
2021-01-05 |
Opko Curna, Llc |
Treatment of collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene
|
WO2010146511A1
(en)
|
2009-06-17 |
2010-12-23 |
Pfizer Limited |
Treatment of overactive bladder
|
JP6073133B2
(ja)
|
2009-06-24 |
2017-02-01 |
クルナ・インコーポレーテッド |
腫瘍壊死因子受容体2(tnfr2)に対する天然アンチセンス転写物の抑制によるtnfr2関連疾患の治療
|
KR101807324B1
(ko)
|
2009-06-26 |
2017-12-08 |
큐알엔에이, 인크. |
다운 증후군 유전자에 대한 천연 안티센스 전사체의 억제에 의한 다운 증후군 유전자 관련된 질환의 치료
|
BRPI1015916A2
(pt)
|
2009-06-26 |
2015-09-01 |
Sea Lane Biotechnologies Llc |
Molécula de ácido nucleico, vetor de expressão, célula hospedeira, bem como método para expressão de um construto de cadeia leve substituta (slc) ou de um polipeptídeo de slc
|
EP2450055B1
(en)
|
2009-06-30 |
2018-01-03 |
Obshestvo S OgranichennoyOtvetstvennostiu"OncoMax" |
Method for suppressing renal tumor growth by blocking fibroblast growth factor receptor
|
WO2011000106A1
(en)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Improved cationic lipids and methods for the delivery of therapeutic agents
|
JP5766188B2
(ja)
|
2009-07-01 |
2015-08-19 |
プロチバ バイオセラピューティクス インコーポレイティッド |
固形腫瘍に治療剤を送達するための脂質製剤
|
US9018187B2
(en)
|
2009-07-01 |
2015-04-28 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods for the delivery of therapeutic agents
|
MX2012000417A
(es)
|
2009-07-07 |
2012-02-08 |
Genentech Inc |
Diagnostico y tratamiento de enfermedades desmielinizantes autoinmunitarias.
|
IN2012DN01449A
(no)
*
|
2009-07-17 |
2015-06-05 |
Univ Denmark Tech Dtu |
|
MX2012000817A
(es)
|
2009-07-21 |
2012-05-08 |
Gilead Calistoga Llc |
Tratamiento para desordenes del higado con inhibidores pi3k.
|
US9937128B2
(en)
|
2009-08-03 |
2018-04-10 |
The University Of North Carolina At Chapel Hill |
Liposomes comprising a calcium phosphate-containing precipitate
|
JP6128848B2
(ja)
|
2009-08-05 |
2017-05-17 |
クルナ・インコーポレーテッド |
インスリン遺伝子(ins)に対する天然アンチセンス転写物の抑制によるインスリン遺伝子(ins)関連疾患の治療
|
AP3574A
(en)
|
2009-08-14 |
2016-02-08 |
Alnylam Pharmaceuticals Inc |
Lipid formulated compositions and methods for inhibiting expression of a gene from the ebola virus
|
RU2576027C2
(ru)
|
2009-08-15 |
2016-02-27 |
Дженентек, Инк. |
Антиангиогенная терапия для лечения ранее подвергавшегося лечению рака молочной железы
|
FR2955324A1
(fr)
|
2010-01-15 |
2011-07-22 |
Sanofi Aventis |
[4-(5-aminomethyl-phenyl)-piperidin-1-yl]-1h-indol-3-yl]-methanones disubstituees
|
WO2011031482A2
(en)
|
2009-08-25 |
2011-03-17 |
Curna, Inc. |
Treatment of 'iq motif containing gtpase activating protein' (iqgap) related diseases by inhibition of natural antisense transcript to iqgap
|
AU2010286361A1
(en)
|
2009-08-31 |
2012-03-15 |
Amplimmune, Inc. |
Methods and compositions for the inhibition of transplant rejection
|
US20110059111A1
(en)
|
2009-09-01 |
2011-03-10 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Mammalian receptors as targets for antibody and active vaccination therapy against mold infections
|
JP5887270B2
(ja)
|
2009-09-02 |
2016-03-16 |
ジェネンテック, インコーポレイテッド |
突然変異体smoothenedおよびその使用方法
|
WO2011041154A1
(en)
|
2009-10-01 |
2011-04-07 |
Metabolex, Inc. |
Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
|
EP3252068A3
(en)
|
2009-10-12 |
2018-03-14 |
Larry J. Smith |
Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
|
JP6016636B2
(ja)
*
|
2009-10-15 |
2016-10-26 |
ジェネンテック, インコーポレイテッド |
改変したレセプター特異性を持つキメラ線維芽細胞増殖因子
|
DK2488204T3
(en)
|
2009-10-16 |
2016-06-06 |
Oncomed Pharm Inc |
Therapeutic combination and use of DLL4 antagonist antibodies and blood pressure lowering agents
|
WO2011049625A1
(en)
|
2009-10-20 |
2011-04-28 |
Mansour Samadpour |
Method for aflatoxin screening of products
|
ES2564207T3
(es)
|
2009-10-22 |
2016-03-18 |
F. Hoffmann-La Roche Ag |
Métodos y composiciones para modular la activación con hepsina de la proteína estimuladora de macrófagos
|
EP2493468A1
(en)
|
2009-10-30 |
2012-09-05 |
Sanofi |
Amino-benzoic acid derivatives for use in the treatment of dihydrogenase-related disorders
|
MY173795A
(en)
|
2009-11-05 |
2020-02-24 |
Incozen Therapeutics Pvt Ltd |
Novel benzopyran kinase modulators
|
US20120244169A1
(en)
|
2009-11-06 |
2012-09-27 |
Fibrogen, Inc. |
Treatment for Radiation-Induced Disorders
|
WO2011062997A2
(en)
|
2009-11-17 |
2011-05-26 |
Musc Foundation For Research Development |
Human monoclonal antibodies to human nucleolin
|
EP3002297B1
(en)
|
2009-11-30 |
2020-04-08 |
F. Hoffmann-La Roche AG |
Antibodies for treating and diagnosing tumors expressing slc34a2 (tat211)
|
US20120269830A1
(en)
|
2009-12-07 |
2012-10-25 |
Lawrence Horowitz |
Conjugates with improved pharmacokinetic properties
|
EP3296398A1
(en)
|
2009-12-07 |
2018-03-21 |
Arbutus Biopharma Corporation |
Compositions for nucleic acid delivery
|
CN104529945A
(zh)
|
2009-12-11 |
2015-04-22 |
基因密码公司 |
使用gdnf家族配体(gfl)模拟剂或ret信号传导通路活化剂促进神经细胞存活的方法
|
WO2011081904A1
(en)
|
2009-12-14 |
2011-07-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Delivery of transthyretin across the blood-brain barrier as a treatment for alzheimer's disease
|
US9173895B2
(en)
|
2009-12-16 |
2015-11-03 |
Curna, Inc. |
Treatment of membrane bound transcription factor peptidase, site 1 (MBTPS1) related diseases by inhibition of natural antisense transcript to MBTPS1
|
US8691227B2
(en)
|
2009-12-17 |
2014-04-08 |
Merck Sharp & Dohme Corp. |
Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α
|
AU2010330814B2
(en)
|
2009-12-18 |
2017-01-12 |
Acuitas Therapeutics Inc. |
Methods and compositions for delivery of nucleic acids
|
KR20120112600A
(ko)
|
2009-12-23 |
2012-10-11 |
사노피 |
[4[4?(5?아미노메틸?2?플루오로?페닐)?피페리딘?1?일]?(1h?피롤로?피리딘?일)?메탄온들 및 이들의 합성
|
HUE028629T2
(en)
|
2009-12-23 |
2016-12-28 |
Synimmune Gmbh |
Anti-FLT3 antibodies and ways of their use
|
SG181501A1
(en)
|
2009-12-23 |
2012-07-30 |
Sanofi Sa |
Prodrugs of [4[4-(5-aminomethyl-2-fluoro-phenyl)-piperidin-1-yl]-(1h-pyrrolo-pyridin-yl)-methanones and synthesis thereof
|
CA2782375C
(en)
|
2009-12-23 |
2023-10-31 |
Opko Curna, Llc |
Treatment of uncoupling protein 2 (ucp2) related diseases by inhibition of natural antisense transcript to ucp2
|
WO2011079261A2
(en)
|
2009-12-23 |
2011-06-30 |
Curna, Inc. |
Treatment of hepatocyte growth factor (hgf) related diseases by inhibition of natural antisense transcript to hgf
|
EP2519542B1
(en)
|
2009-12-28 |
2018-10-10 |
OncoTherapy Science, Inc. |
Anti-cdh3 antibodies and uses thereof
|
JP5993744B2
(ja)
|
2009-12-29 |
2016-09-14 |
カッパーアールエヌエー,インコーポレイテッド |
核呼吸因子1(nrf1)に対する天然アンチセンス転写物の阻害による核呼吸因子1関連疾患の治療
|
WO2011090741A2
(en)
|
2009-12-29 |
2011-07-28 |
Opko Curna, Llc |
TREATMENT OF TUMOR PROTEIN 63 (p63) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO p63
|
WO2011082187A1
(en)
|
2009-12-30 |
2011-07-07 |
Genentech, Inc. |
Methods for modulating a pdgf-aa mediated biological response
|
US8946181B2
(en)
|
2010-01-04 |
2015-02-03 |
Curna, Inc. |
Treatment of interferon regulatory factor 8 (IRF8) related diseases by inhibition of natural antisense transcript to IRF8
|
US8912157B2
(en)
|
2010-01-06 |
2014-12-16 |
Curna, Inc. |
Treatment of pancreatic developmental gene related diseases by inhibition of natural antisense transcript to a pancreatic developmental gene
|
WO2011083845A1
(ja)
*
|
2010-01-08 |
2011-07-14 |
富士フイルム株式会社 |
腫瘍部位に対する標的化剤
|
RU2611191C2
(ru)
|
2010-01-11 |
2017-02-21 |
Курна, Инк. |
Лечение заболеваний, связанных со связывающим половые гормоны глобулином (гспг), путем ингибирования природного антисмыслового транскрипта к гспг
|
TWI535445B
(zh)
|
2010-01-12 |
2016-06-01 |
安可美德藥物股份有限公司 |
Wnt拮抗劑及治療和篩選方法
|
EP2523682B1
(en)
|
2010-01-13 |
2015-12-16 |
Oncomed Pharmaceuticals, Inc. |
Notch1 binding agents and methods of use thereof
|
WO2011090971A2
(en)
|
2010-01-19 |
2011-07-28 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for male reproductive disorders
|
WO2011089211A1
(en)
|
2010-01-22 |
2011-07-28 |
Synimmune Gmbh |
Anti-cd133 antibodies and methods of using the same
|
JP5981850B2
(ja)
|
2010-01-25 |
2016-08-31 |
カッパーアールエヌエー,インコーポレイテッド |
RNaseH1に対する天然アンチセンス転写物の阻害によるRNaseH1関連疾患の治療
|
US8198337B2
(en)
*
|
2010-01-27 |
2012-06-12 |
Momentive Performance Materials Inc. |
Demulsifier compositions and methods for separating emulsions using the same
|
EP2531175A2
(en)
|
2010-02-01 |
2012-12-12 |
Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. |
Liposomes comprising amphipathic drugs and method for their preparation
|
CN102844435B
(zh)
|
2010-02-22 |
2017-05-10 |
库尔纳公司 |
通过抑制吡咯啉‑5‑羧酸还原酶1(pycr1)的天然反义转录物而治疗pycr1相关疾病
|
CN103237810A
(zh)
|
2010-02-23 |
2013-08-07 |
霍夫曼-拉罗奇有限公司 |
用于治疗卵巢癌的抗血管发生疗法
|
JP5972176B2
(ja)
|
2010-02-23 |
2016-08-17 |
サノフイ |
抗アルファ2インテグリン抗体及びそれらの使用
|
KR20130004579A
(ko)
|
2010-02-23 |
2013-01-11 |
제넨테크, 인크. |
종양의 진단 및 치료를 위한 조성물 및 방법
|
AR080291A1
(es)
|
2010-02-24 |
2012-03-28 |
Rinat Neuroscience Corp |
Anticuerpos antagonistas anti receptor de il-7 y procedimientos
|
EP2538929A4
(en)
|
2010-02-25 |
2014-07-09 |
Univ Johns Hopkins |
PROLONGED DELIVERY OF THERAPEUTIC AGENTS TO AN OCULAR COMPARTMENT
|
SA111320266B1
(ar)
|
2010-03-11 |
2015-06-21 |
رينات نيوروساينس كوربوريشن |
أجسام مضادة مع ارتباط مولد مضاد يعتمد على الأس الهيدروجيني
|
KR101878369B1
(ko)
|
2010-03-22 |
2018-07-16 |
제넨테크, 인크. |
단백질-함유 제제의 안정화에 유용한 조성물 및 방법
|
WO2011119852A1
(en)
|
2010-03-24 |
2011-09-29 |
Rxi Pharmaceuticals Corporation |
Reduced size self-delivering rnai compounds
|
CA2793959C
(en)
|
2010-03-25 |
2019-06-04 |
Oregon Health & Science University |
Cmv glycoproteins and recombinant vectors
|
MX341925B
(es)
|
2010-03-29 |
2016-09-07 |
Zymeworks Inc |
Anticuerpos con funcion efectora suprimida o mejorada.
|
CA2792291A1
(en)
|
2010-03-29 |
2011-10-06 |
Kumamoto University |
Sirna therapy for transthyretin (ttr) related ocular amyloidosis
|
HUE038788T2
(hu)
|
2010-03-31 |
2018-11-28 |
Boehringer Ingelheim Int |
Anti-CD40 antitestek
|
EP3290428B1
(en)
|
2010-03-31 |
2021-10-13 |
Gilead Pharmasset LLC |
Tablet comprising crystalline (s)-isopropyl 2-(((s)-(((2r,3r,4r,5r)-5-(2,4-dioxo-3,4-dihydropyrimidin-1 (2h)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
|
US8563530B2
(en)
|
2010-03-31 |
2013-10-22 |
Gilead Pharmassel LLC |
Purine nucleoside phosphoramidate
|
CA2794671C
(en)
|
2010-03-31 |
2018-05-01 |
Gilead Pharmasset Llc |
Stereoselective synthesis of phosphorus containing actives
|
WO2011123621A2
(en)
|
2010-04-01 |
2011-10-06 |
Alnylam Pharmaceuticals Inc. |
2' and 5' modified monomers and oligonucleotides
|
WO2011125015A2
(en)
|
2010-04-05 |
2011-10-13 |
Bar-Ilan University |
Protease-activatable pore-forming polypeptides
|
JP2013523162A
(ja)
|
2010-04-06 |
2013-06-17 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
Cd274/pd−l1遺伝子の発現を阻害するための組成物および方法
|
TWI644675B
(zh)
|
2010-04-09 |
2018-12-21 |
可娜公司 |
藉由抑制纖維母細胞生長因子21(fgf21)之天然反義轉錄物以治療fgf21相關疾病
|
US20130260460A1
(en)
|
2010-04-22 |
2013-10-03 |
Isis Pharmaceuticals Inc |
Conformationally restricted dinucleotide monomers and oligonucleotides
|
WO2011133871A2
(en)
|
2010-04-22 |
2011-10-27 |
Alnylam Pharmaceuticals, Inc. |
5'-end derivatives
|
US10913767B2
(en)
|
2010-04-22 |
2021-02-09 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising acyclic and abasic nucleosides and analogs
|
WO2011137114A1
(en)
|
2010-04-26 |
2011-11-03 |
Abraxis Bioscience, Llc |
Sparc binding antibodies and uses thereof
|
JP5787323B2
(ja)
*
|
2010-04-28 |
2015-09-30 |
国立大学法人北海道大学 |
脂質膜構造体
|
NZ603339A
(en)
|
2010-04-29 |
2015-01-30 |
Isis Pharmaceuticals Inc |
Modulation of transthyretin expression
|
US20130156845A1
(en)
|
2010-04-29 |
2013-06-20 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated single stranded rna
|
NZ603226A
(en)
|
2010-04-30 |
2015-02-27 |
Alexion Pharma Inc |
Anti-c5a antibodies and methods for using the antibodies
|
KR101992076B1
(ko)
|
2010-05-03 |
2019-06-21 |
큐알엔에이, 인크. |
시르투인 (sirt)에 대한 자연 안티센스 전사체의 저해에 의한 시르투인 (sirt) 관련된 질환의 치료
|
JP2013525484A
(ja)
|
2010-05-03 |
2013-06-20 |
ジェネンテック, インコーポレイテッド |
タンパク質含有製剤の粘度を低減させるために有用な組成物及び方法
|
RU2636461C2
(ru)
|
2010-05-03 |
2017-11-23 |
Дженентек, Инк. |
Композиции и способы для диагностики и лечения опухоли
|
EP2569430B1
(en)
|
2010-05-12 |
2018-10-17 |
The Trustees of Columbia University in the City of New York |
Methods for producing enteroendocrine cells that make and secrete insulin
|
TWI531370B
(zh)
|
2010-05-14 |
2016-05-01 |
可娜公司 |
藉由抑制par4天然反股轉錄本治療par4相關疾病
|
EA025281B9
(ru)
|
2010-05-17 |
2017-08-31 |
Инкозен Терапьютикс Пвт. Лтд. |
СОЕДИНЕНИЯ 3,5-ДИЗАМЕЩЕННОГО-3H-ИМИДАЗО[4,5-b]ПИРИДИНА И 3,5-ДИЗАМЕЩЕННОГО-3H-[1,2,3]ТРИАЗОЛО[4,5-b]ПИРИДИНА КАК МОДУЛЯТОРЫ ПРОТЕИНКИНАЗ
|
CA2800348C
(en)
|
2010-05-18 |
2020-07-21 |
Lena A. Basile |
Il-12 formulations for enhancing hematopoiesis
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
EP3299464B1
(en)
|
2010-05-26 |
2019-10-02 |
CuRNA, Inc. |
Treatment of atonal homolog 1 (atoh1) related diseases by inhibition of natural antisense transcript to atoh1
|
WO2011153323A2
(en)
|
2010-06-02 |
2011-12-08 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods directed to treating liver fibrosis
|
WO2011153243A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Anti-angiogenesis therapy for treating gastric cancer
|
US9527924B2
(en)
|
2010-06-02 |
2016-12-27 |
Dana-Farber Cancer Institute, Inc. |
Humanized monoclonal antibodies and methods of use
|
IL300109A
(en)
|
2010-06-03 |
2023-03-01 |
Alnylam Pharmaceuticals Inc |
Biodegradable lipids for the transfer of active substances
|
CA2801182A1
(en)
|
2010-06-16 |
2011-12-22 |
Metabolex, Inc. |
Gpr120 receptor agonists and uses thereof
|
US8299117B2
(en)
|
2010-06-16 |
2012-10-30 |
Metabolex Inc. |
GPR120 receptor agonists and uses thereof
|
CN103153283B
(zh)
|
2010-06-19 |
2017-05-17 |
健康科学西部大学 |
Peg化脂质体包封的糖肽抗生素的新制剂
|
JP5847813B2
(ja)
|
2010-06-23 |
2016-01-27 |
シマベイ セラピューティクス, インコーポレーテッド |
5−エチル−2−{4−[4−(4−テトラゾル−1−イル−フェノキシメチル)−チアゾール−2−イル]−ピペリジン−1−イル}−ピリミジンの組成物
|
MY161390A
(en)
|
2010-06-24 |
2017-04-14 |
Genentech Inc |
Compositions and methods containing alkylglycosides for stabilizing protein-containing formulations
|
CN102309448B
(zh)
*
|
2010-06-29 |
2014-07-09 |
中国人民解放军军事医学科学院毒物药物研究所 |
一种肺部给药的环丙沙星药用组合物及其制备方法
|
US9006417B2
(en)
|
2010-06-30 |
2015-04-14 |
Protiva Biotherapeutics, Inc. |
Non-liposomal systems for nucleic acid delivery
|
PT2590676T
(pt)
|
2010-07-06 |
2016-11-04 |
Glaxosmithkline Biologicals Sa |
Partículas de transferência de tipo virião para moléculas de arn auto-replicante
|
EP2590626B1
(en)
|
2010-07-06 |
2015-10-28 |
GlaxoSmithKline Biologicals SA |
Liposomes with lipids having an advantageous pka-value for rna delivery
|
ES2646669T3
(es)
|
2010-07-06 |
2017-12-14 |
Glaxosmithkline Biologicals Sa |
Procedimientos de aumento de una respuesta inmunitaria mediante el suministro de ARN
|
WO2012006369A2
(en)
|
2010-07-06 |
2012-01-12 |
Novartis Ag |
Immunisation of large mammals with low doses of rna
|
SG186451A1
(en)
|
2010-07-12 |
2013-01-30 |
Covx Technologies Ireland Ltd |
Multifunctional antibody conjugates
|
NO2593547T3
(no)
|
2010-07-14 |
2018-04-14 |
|
|
EP2596026B1
(en)
|
2010-07-23 |
2020-04-08 |
Trustees of Boston University |
Anti-despr inhibitors as therapeutics for inhibition of pathological angiogenesis and tumor cell invasiveness and for molecular imaging and targeted delivery
|
WO2012016184A2
(en)
|
2010-07-30 |
2012-02-02 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for delivery of active agents
|
US20130202652A1
(en)
|
2010-07-30 |
2013-08-08 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for delivery of active agents
|
WO2012019093A1
(en)
|
2010-08-05 |
2012-02-09 |
Human Biomolecular Research Institute |
Synthetic compounds and methods to decrease nicotine self-administration
|
EP2420250A1
(en)
|
2010-08-13 |
2012-02-22 |
Universitätsklinikum Münster |
Anti-Syndecan-4 antibodies
|
US8900590B2
(en)
|
2010-08-12 |
2014-12-02 |
Theraclone Sciences, Inc. |
Anti-hemagglutinin antibody compositions and methods of use thereof
|
PT4043040T
(pt)
|
2010-08-31 |
2023-03-24 |
Glaxosmithkline Biologicals Sa |
Lipossomas pequenos para entrega de arn que codifica um imunogénio
|
PL3981427T3
(pl)
*
|
2010-08-31 |
2022-09-19 |
Glaxosmithkline Biologicals S.A. |
Pegylowane liposomy do dostarczania rna kodującego immunogen
|
CA3109036C
(en)
|
2010-08-31 |
2023-08-01 |
Theraclone Sciences, Inc. |
Human immunodeficiency virus (hiv)-neutralizing antibodies
|
US8551479B2
(en)
|
2010-09-10 |
2013-10-08 |
Oncomed Pharmaceuticals, Inc. |
Methods for treating melanoma
|
DK2625197T3
(en)
|
2010-10-05 |
2016-10-03 |
Genentech Inc |
Smoothened MUTANT AND METHODS OF USING THE SAME
|
CA2813901C
(en)
|
2010-10-06 |
2019-11-12 |
Curna, Inc. |
Treatment of sialidase 4 (neu4) related diseases by inhibition of natural antisense transcript to neu4
|
TR201903651T4
(tr)
|
2010-10-11 |
2019-04-22 |
Glaxosmithkline Biologicals Sa |
Antijen uygulama platformları.
|
US9222088B2
(en)
|
2010-10-22 |
2015-12-29 |
Curna, Inc. |
Treatment of alpha-L-iduronidase (IDUA) related diseases by inhibition of natural antisense transcript to IDUA
|
TW201307385A
(zh)
|
2010-10-25 |
2013-02-16 |
Genentech Inc |
胃腸炎症和銀屑病以及哮喘的治療
|
US20130210893A1
(en)
|
2010-10-27 |
2013-08-15 |
Curna, Inc. |
Treatment of interferon-related developmental regulator 1 (ifrd1) related diseases by inhibition of natural antisense transcript to ifrd1
|
BR112013011065B1
(pt)
|
2010-11-04 |
2022-03-15 |
Boehringer Ingelheim International Gmbh |
Anticorpo anti-il-23p19 humanizado ou seu fragmento de ligação ao antígeno, seu uso e composição farmacêutica
|
WO2012061811A2
(en)
|
2010-11-05 |
2012-05-10 |
Fibrogen, Inc. |
Treatment method for lung remodeling diseases
|
CN103370054A
(zh)
|
2010-11-09 |
2013-10-23 |
阿尔尼拉姆医药品有限公司 |
用于抑制Eg5和VEGF基因的表达的脂质配制的组合物和方法
|
US9518114B2
(en)
|
2010-11-12 |
2016-12-13 |
Purdue Research Foundation |
Treating bladder tumor cells using fibronectin attachment protein as a target
|
WO2012099566A1
(en)
|
2010-11-17 |
2012-07-26 |
Sea Lane Biotechnologies, Llc |
Influenza virus neutralizing agents that mimic the binding site of an influenza neutralizing antibody
|
CA2817250A1
(en)
|
2010-11-18 |
2012-05-24 |
The General Hospital Corporation |
Novel compositions and uses of anti-hypertension agents for cancer therapy
|
JP6071893B2
(ja)
|
2010-11-23 |
2017-02-01 |
カッパーアールエヌエー,インコーポレイテッド |
Nanogへの天然アンチセンス転写物の阻害によるnanog関連疾患の治療
|
WO2012075140A1
(en)
|
2010-11-30 |
2012-06-07 |
Pharmasset, Inc. |
Compounds
|
EP2648763A4
(en)
|
2010-12-10 |
2014-05-14 |
Alnylam Pharmaceuticals Inc |
COMPOSITIONS AND METHODS FOR EXPRESSION INHIBITION OF GENES KLF-1 AND BCL11A
|
EP2649182A4
(en)
|
2010-12-10 |
2015-05-06 |
Alnylam Pharmaceuticals Inc |
COMPOSITIONS AND METHOD FOR INCREASING AN ERYTHROPOIETIN (EPO) PREPARATION
|
BR112013014735A2
(pt)
|
2010-12-14 |
2016-10-04 |
Rigshospitalet |
captura de radionuclídeos em composições de nanopartículas
|
EP2468259A1
(en)
*
|
2010-12-23 |
2012-06-27 |
Traslational Cancer Drugs Pharma, S.L. |
Pharmaceutical compositions of pyridinium and quinolinium derivatives
|
US10016389B2
(en)
|
2011-01-05 |
2018-07-10 |
Livon Laboratories |
Method of making liposomes, liposome compositions made by the methods, and methods of using the same
|
AU2012207606B2
(en)
|
2011-01-11 |
2017-02-23 |
Alnylam Pharmaceuticals, Inc. |
Pegylated lipids and their use for drug delivery
|
CA2821985C
(en)
|
2011-01-11 |
2019-07-09 |
Dimerix Bioscience Pty Ltd |
Combination therapy
|
MX365647B
(es)
|
2011-02-02 |
2019-06-10 |
Excaliard Pharmaceuticals Inc |
El uso de compuestos antisentido dirigidos al factor de crecimiento del tejido conectivo (ctgf) para tratar queloides o cicatrices hipertroficas.
|
RU2440142C1
(ru)
|
2011-02-07 |
2012-01-20 |
Общество С Ограниченной Ответственностью "Онкомакс" |
Антитело, останавливающее или замедляющее рост опухоли (варианты), способ подавления роста опухоли, способ диагностики злокачественных образований
|
WO2012109495A1
(en)
|
2011-02-09 |
2012-08-16 |
Metabolic Solutions Development Company, Llc |
Cellular targets of thiazolidinediones
|
KR20140012098A
(ko)
|
2011-02-14 |
2014-01-29 |
테라클론 사이언시스, 아이엔씨. |
인플루엔자의 치료 및 진단을 위한 조성물 및 방법
|
PL226015B1
(pl)
*
|
2011-03-03 |
2017-06-30 |
Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną |
Liposomowy preparat zawierajacy przeciwnowotworowa substancje aktywna, sposob jego wytwarzania i zawierajaca go kompozycja farmaceutyczna
|
AU2012225310B2
(en)
|
2011-03-09 |
2017-08-03 |
Cell Signaling Technology, Inc. |
Methods and reagents for creating monoclonal antibodies
|
SG193402A1
(en)
|
2011-03-15 |
2013-10-30 |
Theraclone Sciences Inc |
Compositions and methods for the therapy and diagnosis of influenza
|
AU2012228990B2
(en)
|
2011-03-16 |
2017-04-06 |
Amgen Inc. |
Potent and selective inhibitors of Nav1.3 and Nav1.7
|
US10184942B2
(en)
|
2011-03-17 |
2019-01-22 |
University Of South Florida |
Natriuretic peptide receptor as a biomarker for diagnosis and prognosis of cancer
|
WO2012134975A1
(en)
|
2011-03-28 |
2012-10-04 |
St. Jude Children's Research Hospital |
Methods and compositions employing immunogenic fusion proteins
|
MX343008B
(es)
|
2011-03-29 |
2016-10-21 |
Alnylam Pharmaceuticals Inc |
Composiciones y metodos para inhibir la expresion del gen de proteasa transmembrana, serina 6 (tmprss6).
|
CA2831732C
(en)
|
2011-03-31 |
2019-12-31 |
Genentech, Inc. |
Use of a monoclonal anti-beta7 antibody for treating gastrointestinal inflammatory disorders
|
EP2508176A1
(en)
|
2011-04-08 |
2012-10-10 |
Lipotarg Gmbh |
Novel combination treatment of cancer
|
CA2832972C
(en)
|
2011-04-13 |
2019-04-30 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of ptp1b expression
|
MX338353B
(es)
|
2011-04-20 |
2016-04-13 |
Medimmune Llc |
Anticuerpos y otras moleculas que se unen a b7 - h1 y pd - 1.
|
KR101589135B1
(ko)
|
2011-04-20 |
2016-01-29 |
주식회사 셀앤바이오 |
인간화 항-emapii 항체 및 이의 용도
|
SI2705029T1
(sl)
|
2011-05-04 |
2019-03-29 |
Rhizen Pharmaceuticals S.A. |
Nove spojine kot modulatori protein-kinaz
|
US8846042B2
(en)
|
2011-05-16 |
2014-09-30 |
Fabion Pharmaceuticals, Inc. |
Multi-specific FAB fusion proteins and methods of use
|
WO2012166903A1
(en)
|
2011-06-02 |
2012-12-06 |
President And Fellows Of Harvard College |
Methods and uses for ex vivo tissue culture systems
|
US9593330B2
(en)
|
2011-06-09 |
2017-03-14 |
Curna, Inc. |
Treatment of frataxin (FXN) related diseases by inhibition of natural antisense transcript to FXN
|
CA2832109C
(en)
|
2011-06-10 |
2021-07-06 |
Oregon Health & Science University |
Cmv glycoproteins and recombinant vectors
|
CA2839437A1
(en)
|
2011-06-16 |
2012-12-20 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of fibroblast growth factor receptor 4 expression
|
WO2012177906A1
(en)
|
2011-06-21 |
2012-12-27 |
Alnylam Pharmaceuticals, Inc. |
Assays and methods for determining activity of a therapeutic agent in a subject
|
WO2012177949A2
(en)
|
2011-06-21 |
2012-12-27 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibition of expression of protein c (proc) genes
|
CA3191066A1
(en)
|
2011-06-21 |
2012-12-27 |
Alnylam Pharmaceuticals Inc. |
Compositions and methods for inhibition of expression of apolipoprotein c-iii (apoc3) genes
|
EP2537532A1
(en)
|
2011-06-22 |
2012-12-26 |
J. Stefan Institute |
Cathepsin-binding compounds bound to a nanodevice and their diagnostic and therapeutic use
|
EP3597750B1
(en)
|
2011-06-23 |
2022-05-04 |
Alnylam Pharmaceuticals, Inc. |
Serpina1 sirnas: compositions of matter and methods of treatment
|
AU2012275841A1
(en)
|
2011-06-27 |
2014-01-16 |
The Jackson Laboratory |
Methods and compositions for treatment of cancer and autoimmune disease
|
US20150045540A1
(en)
|
2011-06-28 |
2015-02-12 |
Sea Lane Biotechnologies, Llc |
Multispecific stacked variable domain binding proteins
|
CA2840989A1
(en)
|
2011-07-06 |
2013-01-10 |
Novartis Ag |
Immunogenic combination compositions and uses thereof
|
US10085940B2
(en)
|
2011-07-13 |
2018-10-02 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Liposomes co-encapsulating a bisphosphonate and an amphipathic agent
|
BR112014000392A2
(pt)
|
2011-07-14 |
2017-02-21 |
Pfizer |
tratamento com anticorpos anti-pcsk9
|
US9120858B2
(en)
|
2011-07-22 |
2015-09-01 |
The Research Foundation Of State University Of New York |
Antibodies to the B12-transcobalamin receptor
|
US20130022551A1
(en)
|
2011-07-22 |
2013-01-24 |
Trustees Of Boston University |
DEspR ANTAGONISTS AND AGONISTS AS THERAPEUTICS
|
WO2013015821A1
(en)
|
2011-07-22 |
2013-01-31 |
The Research Foundation Of State University Of New York |
Antibodies to the b12-transcobalamin receptor
|
WO2013019857A2
(en)
|
2011-08-01 |
2013-02-07 |
Alnylam Pharmaceuticals, Inc. |
Method for improving the success rate of hematopoietic stem cell transplants
|
JP6120848B2
(ja)
|
2011-08-15 |
2017-04-26 |
メディミューン,エルエルシー |
抗b7−h4抗体およびその使用
|
FR2979239A1
(fr)
*
|
2011-08-25 |
2013-03-01 |
Trophos |
Liposome comprenant au moins un derive de cholesterol
|
WO2013033069A1
(en)
|
2011-08-30 |
2013-03-07 |
Theraclone Sciences, Inc. |
Human rhinovirus (hrv) antibodies
|
DK2751279T3
(da)
|
2011-08-31 |
2017-11-20 |
St Jude Children's Res Hospital |
Fremgangsmåder og sammensætninger til påvisning af niveauet af lysosomal exocytose-aktivitet og fremgangsmåder til anvendelse
|
MY170725A
(en)
|
2011-09-09 |
2019-08-27 |
Univ Osaka |
Dengue-virus serotype neutralizing antibodies
|
AU2012216792A1
(en)
|
2011-09-12 |
2013-03-28 |
International Aids Vaccine Initiative |
Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies
|
AU2012312654B2
(en)
|
2011-09-19 |
2017-04-13 |
Gencia Corporation |
Modified creatine compounds
|
EP3401401B1
(en)
|
2011-09-20 |
2020-04-15 |
Ionis Pharmaceuticals, Inc. |
Antisense modulation of gcgr expression
|
WO2013041687A1
(en)
|
2011-09-23 |
2013-03-28 |
Amgen Research (Munich) Gmbh |
Bispecific binding molecules for 5t4 and cd3
|
EP3485903B1
(en)
|
2011-09-23 |
2022-11-16 |
Mereo BioPharma 5, Inc. |
Vegf/dll4 binding agents and uses thereof
|
JP2014530001A
(ja)
|
2011-09-23 |
2014-11-17 |
テクノファージ, インベスティガサン エデセンボルビメント エム ビオテクノロジア,エスエー |
抗腫瘍壊死因子−α剤及びその使用
|
EP3456317A1
(en)
|
2011-09-27 |
2019-03-20 |
Alnylam Pharmaceuticals, Inc. |
Di-aliphatic substituted pegylated lipids
|
KR102162901B1
(ko)
|
2011-09-29 |
2020-10-08 |
피엘엑스 옵코 인코포레이티드 |
위장관을 따라 약물을 표적화 방출하기 위한 pH 감응성 담체, 그로부터의 조성물, 및 이들의 제조 및 사용 방법
|
US20130085139A1
(en)
|
2011-10-04 |
2013-04-04 |
Royal Holloway And Bedford New College |
Oligomers
|
EP2763698B1
(en)
|
2011-10-06 |
2020-12-02 |
ImmunoVaccine Technologies Inc. |
Liposome compositions comprising an adjuvant that activates or increases the activity of tlr2 and uses thereof
|
ES2687951T3
(es)
|
2011-10-14 |
2018-10-30 |
F. Hoffmann-La Roche Ag |
Anticuerpos anti-HtrA1 y procedimientos de uso
|
US8883989B2
(en)
|
2011-10-18 |
2014-11-11 |
Regents Of The University Of Minnesota |
Fractalkine binding polynucleotides and methods of use
|
IN2014CN03749A
(no)
|
2011-10-25 |
2015-09-25 |
Isis Pharmaceuticals Inc |
|
EP2586461A1
(en)
|
2011-10-27 |
2013-05-01 |
Christopher L. Parks |
Viral particles derived from an enveloped virus
|
TW201325613A
(zh)
|
2011-10-28 |
2013-07-01 |
Genentech Inc |
治療黑色素瘤之治療組合及方法
|
CN104039826A
(zh)
|
2011-10-31 |
2014-09-10 |
弗·哈夫曼-拉罗切有限公司 |
抗体制剂
|
TWI480042B
(zh)
*
|
2011-11-03 |
2015-04-11 |
Taiwan Liposome Co Ltd |
疏水性喜樹鹼衍生物之醫藥組合物
|
US10980798B2
(en)
|
2011-11-03 |
2021-04-20 |
Taiwan Liposome Company, Ltd. |
Pharmaceutical compositions of hydrophobic camptothecin derivatives
|
SA112330988B1
(ar)
|
2011-11-11 |
2015-07-22 |
رينات نيوروساينس كورب. |
أجسام مضادة تخص trop-2 واستخداماتها
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
HUE047437T2
(hu)
|
2011-11-16 |
2020-04-28 |
Boehringer Ingelheim Int |
Anti-IL-36R antitestek
|
WO2013090293A1
(en)
|
2011-12-15 |
2013-06-20 |
The University Of Chicago |
Methods and compositions for cancer therapy using mutant light molecules with increased affinity to receptors
|
WO2013093693A1
(en)
|
2011-12-22 |
2013-06-27 |
Rinat Neuroscience Corp. |
Staphylococcus aureus specific antibodies and uses thereof
|
CN104169301A
(zh)
|
2011-12-22 |
2014-11-26 |
瑞纳神经科学公司 |
人生长激素受体拮抗剂抗体及其使用方法
|
WO2013093809A1
(en)
|
2011-12-23 |
2013-06-27 |
Pfizer Inc. |
Engineered antibody constant regions for site-specific conjugation and methods and uses therefor
|
WO2013101771A2
(en)
|
2011-12-30 |
2013-07-04 |
Genentech, Inc. |
Compositions and method for treating autoimmune diseases
|
EP2802355B1
(en)
|
2012-01-09 |
2018-09-05 |
CovX Technologies Ireland Limited |
Mutant antibodies and conjugation thereof
|
CA2862290A1
(en)
|
2012-01-18 |
2013-10-17 |
Neumedicines, Inc. |
Il-12 for radiation protection and radiation-induced toxicity mitigation
|
AU2013209512B2
(en)
|
2012-01-20 |
2017-08-03 |
I2 Pharmaceuticals, Inc. |
Surrobody cojugates
|
US20150004219A1
(en)
|
2012-02-02 |
2015-01-01 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. |
Stable liposomes for drug delivery
|
NZ628314A
(en)
|
2012-02-06 |
2017-01-27 |
Inhibrx Lp |
Cd47 antibodies and methods of use thereof
|
US20130230457A1
(en)
*
|
2012-02-17 |
2013-09-05 |
Celsion Corporation |
Thermosensitive Nanoparticle Formulations and Method of Making The Same
|
US9138492B2
(en)
*
|
2012-02-23 |
2015-09-22 |
Canon Kabushiki Kaisha |
Particle containing hydrophobic dye having cyanine structure, and contrast agent containing the particle
|
EP2820047B1
(en)
|
2012-03-01 |
2018-04-25 |
Amgen Research (Munich) GmbH |
Long life polypeptide binding molecules
|
AU2013203620B2
(en)
|
2012-03-05 |
2015-11-19 |
Gilead Calistoga Llc |
Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
|
WO2013138374A2
(en)
|
2012-03-15 |
2013-09-19 |
Curna, Inc. |
Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf
|
ES2651692T3
(es)
|
2012-03-29 |
2018-01-29 |
Novimmune Sa |
Anticuerpos anti-TLR4 y sus usos
|
JP6192708B2
(ja)
|
2012-03-30 |
2017-09-06 |
ライゼン・ファーマシューティカルズ・エスアー |
C−metプロテインキナーゼ調節物質としての新規3,5−二置換−3h−イミダゾ[4,5−b]ピリジン化合物および3,5−二置換−3h−[1,2,3]トリアゾロ[4,5−b]ピリジン化合物
|
WO2013151649A1
(en)
|
2012-04-04 |
2013-10-10 |
Sialix Inc |
Glycan-interacting compounds
|
US9133461B2
(en)
|
2012-04-10 |
2015-09-15 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of the ALAS1 gene
|
JP2015516400A
(ja)
|
2012-04-24 |
2015-06-11 |
ユニバーシティー オブ マイアミUniversity Of Miami |
侵襲的かつ多剤耐性の病原体に対するパーフォリン2の防御
|
CA2871985C
(en)
|
2012-05-03 |
2023-10-10 |
Boehringer Ingelheim International Gmbh |
Anti-il-23p19 antibodies
|
CA2872519C
(en)
|
2012-05-04 |
2017-09-05 |
The Johns Hopkins University |
Lipid-based drug carriers for rapid penetration through mucus linings
|
WO2013166500A1
(en)
|
2012-05-04 |
2013-11-07 |
Dana-Farber Cancer Institute, Inc. |
Affinity matured anti-ccr4 humanized monoclonal antibodies and methods of use
|
AU2013202947B2
(en)
|
2012-06-13 |
2016-06-02 |
Ipsen Biopharm Ltd. |
Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan
|
US9717724B2
(en)
|
2012-06-13 |
2017-08-01 |
Ipsen Biopharm Ltd. |
Methods for treating pancreatic cancer using combination therapies
|
CN104582732A
(zh)
|
2012-06-15 |
2015-04-29 |
布里格姆及妇女医院股份有限公司 |
治疗癌症的组合物及其制造方法
|
US9856314B2
(en)
|
2012-06-22 |
2018-01-02 |
Cytomx Therapeutics, Inc. |
Activatable antibodies having non-binding steric moieties and methods of using the same
|
EP2679596B1
(en)
|
2012-06-27 |
2017-04-12 |
International Aids Vaccine Initiative |
HIV-1 env glycoprotein variant
|
JP2015524410A
(ja)
*
|
2012-07-18 |
2015-08-24 |
オニキス セラピューティクス, インク.Onyx Therapeutics, Inc. |
エポキシケトン系プロテアソーム阻害剤のリポソーム組成物
|
US8603470B1
(en)
|
2012-08-07 |
2013-12-10 |
National Cheng Kung University |
Use of IL-20 antagonists for treating liver diseases
|
CN103565745A
(zh)
*
|
2012-08-10 |
2014-02-12 |
德克萨斯州大学系统董事会 |
用于治疗中风的神经保护性脂质体组合物和方法
|
WO2014027959A1
(en)
|
2012-08-14 |
2014-02-20 |
Nanyang Technological University |
Angiopoietin-like 4 antibody and a method of its use in cancer treatment
|
WO2014039533A2
(en)
|
2012-09-04 |
2014-03-13 |
Eleison Pharmaceuticals, Llc |
Preventing pulmonary recurrence of cancer with lipid-complexed cisplatin
|
US20160136159A1
(en)
|
2012-09-17 |
2016-05-19 |
Chemedest Ltd. |
Method for Treating Peripheral Neuropathy
|
CN107892719B
(zh)
|
2012-10-04 |
2022-01-14 |
达纳-法伯癌症研究所公司 |
人单克隆抗-pd-l1抗体和使用方法
|
RU2015112024A
(ru)
|
2012-10-05 |
2016-11-27 |
Дженентек, Инк. |
Способы диагностики и лечения воспалительного заболевания кишечника
|
CA2887711A1
(en)
|
2012-10-23 |
2014-05-01 |
Oncomed Pharmaceuticals, Inc. |
Methods of treating neuroendocrine tumors using wnt pathway-binding agents
|
JP6371294B2
(ja)
|
2012-10-31 |
2018-08-08 |
オンコメッド ファーマシューティカルズ インコーポレイテッド |
Dll4アンタゴニストによる処置の方法およびモニタリング
|
JP6392770B2
(ja)
|
2012-12-03 |
2018-09-19 |
ノビミューン エスアー |
抗cd47抗体およびその使用方法
|
CA2894846A1
(en)
|
2012-12-12 |
2014-06-19 |
Temple University - Of The Commonwealth System Of Higher Education |
Compositions and methods for treatment of cancer
|
EP2934303B1
(en)
|
2012-12-19 |
2019-09-04 |
The Research Foundation for the State University of New York |
Compositions and method for light triggered release of materials from nanovesicles
|
CA2894879A1
(en)
|
2012-12-19 |
2014-06-26 |
Amplimmune, Inc. |
B7-h4 specific antibodies, and compositions and methods of use thereof
|
EP2935311B1
(en)
|
2012-12-20 |
2021-03-31 |
Amgen Inc. |
Apj receptor agonists and uses thereof
|
GB201223053D0
(en)
|
2012-12-20 |
2013-02-06 |
Medical Res Council |
Receptor
|
MX2015008117A
(es)
|
2012-12-21 |
2016-03-31 |
Amplimmune Inc |
Anticuerpos anti-h7cr.
|
ES2847930T3
(es)
|
2013-01-07 |
2021-08-04 |
Mucosal Vaccine Tech Llc |
Vacunas terapéuticas para el tratamiento de las infecciones por el virus del herpes simple de tipo 2
|
ES2728936T3
(es)
|
2013-01-25 |
2019-10-29 |
Amgen Inc |
Anticuerpos dirigidos contra CDH19 para melanoma
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
US10568975B2
(en)
|
2013-02-05 |
2020-02-25 |
The Johns Hopkins University |
Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof
|
SG11201506132PA
(en)
|
2013-02-06 |
2015-09-29 |
Inhibrx Llc |
Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof
|
EP2956169B1
(en)
|
2013-02-12 |
2018-04-11 |
THE UNITED STATES OF AMERICA, represented by the S |
Monoclonal antibodies that neutralize norovirus
|
UY35397A
(es)
|
2013-03-12 |
2014-10-31 |
Amgen Inc |
INHIBIDORES POTENTES Y SELECTIVOS DE NaV1.7
|
US9302005B2
(en)
|
2013-03-14 |
2016-04-05 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating cancer
|
JP2016513712A
(ja)
|
2013-03-14 |
2016-05-16 |
ジェローム, ジェイ. シェンターク, |
カイロミクロンへの分子の取り込みのためのコレストソーム小胞
|
AR095374A1
(es)
|
2013-03-15 |
2015-10-14 |
Amgen Res (Munich) Gmbh |
Moléculas de unión para bcma y cd3
|
SI2970449T1
(sl)
|
2013-03-15 |
2019-11-29 |
Amgen Res Munich Gmbh |
Enoverižne vezavne molekule, ki vsebujejo N-terminalni ABP
|
EP3689902B1
(en)
|
2013-03-15 |
2023-06-28 |
Dana-Farber Cancer Institute, Inc. |
Flavivirus neutralizing antibodies and methods of use thereof
|
WO2014140368A1
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Research (Munich) Gmbh |
Antibody constructs for influenza m2 and cd3
|
WO2014145037A1
(en)
*
|
2013-03-15 |
2014-09-18 |
M. Alphabet 3, L.L.C. |
Methods and compositions for enhancing oxygen levels in tissues
|
US20140283157A1
(en)
|
2013-03-15 |
2014-09-18 |
Diadexus, Inc. |
Lipoprotein-associated phospholipase a2 antibody compositions and methods of use
|
WO2014152497A2
(en)
|
2013-03-15 |
2014-09-25 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for cognitive disorders
|
WO2014145654A1
(en)
|
2013-03-15 |
2014-09-18 |
The Trustees Of The University Of Pennsylvania |
Method for the site-specific covalent cross-linking of antibodies to surfaces
|
KR20150132473A
(ko)
|
2013-03-15 |
2015-11-25 |
다이액스 코포레이션 |
항-혈장 칼리크레인 항체
|
RU2015143130A
(ru)
|
2013-03-15 |
2017-04-21 |
Дженсиа Корпорейшен |
Композиции и способы лечения состояний, поражающих эпидермис
|
SG11201507974RA
(en)
|
2013-03-27 |
2015-10-29 |
Genentech Inc |
Use of biomarkers for assessing treatment of gastrointestinal inflammatory disorders with beta7 integrin antagonists
|
WO2014160871A2
(en)
|
2013-03-27 |
2014-10-02 |
The General Hospital Corporation |
Methods and agents for treating alzheimer's disease
|
JP6462663B2
(ja)
|
2013-04-12 |
2019-01-30 |
アイカーン スクール オブ メディシン アット マウント シナイ |
心的外傷後ストレス障害を処置するための方法
|
JP2016518140A
(ja)
|
2013-05-03 |
2016-06-23 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
I型インターフェロンの環状ジヌクレオチド誘導法
|
AU2014262843B2
(en)
|
2013-05-06 |
2017-06-22 |
Scholar Rock, Inc. |
Compositions and methods for growth factor modulation
|
TW201515650A
(zh)
|
2013-05-06 |
2015-05-01 |
艾爾妮蘭製藥公司 |
遞送經脂質調配之核酸分子之劑量及方法
|
US9248189B2
(en)
|
2013-05-07 |
2016-02-02 |
Pfizer Inc. |
Anti-glucagon receptor antibodies and pharmaceutical compositions thereof
|
EP2994163B1
(en)
|
2013-05-09 |
2019-08-28 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Single-domain vhh antibodies directed to norovirus gi.1 and gii.4 and their use
|
BR112015029395A2
(pt)
|
2013-05-24 |
2017-09-19 |
Medimmune Llc |
Anticorpos anti-b7-h5 e seus usos
|
KR20160015286A
(ko)
|
2013-05-31 |
2016-02-12 |
제넨테크, 인크. |
항-세포벽 테이코산 항체 및 접합체
|
KR20160015227A
(ko)
|
2013-05-31 |
2016-02-12 |
제넨테크, 인크. |
항-세포벽 테이코산 항체 및 접합체
|
NZ714765A
(en)
|
2013-06-06 |
2021-12-24 |
Pf Medicament |
Anti-c10orf54 antibodies and uses thereof
|
DK3007704T3
(da)
|
2013-06-13 |
2021-03-29 |
Antisense Therapeutics Ltd |
Kombinationsterapi til akromegali
|
US10208125B2
(en)
|
2013-07-15 |
2019-02-19 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Anti-mucin 1 binding agents and uses thereof
|
ES2683268T3
(es)
|
2013-07-25 |
2018-09-25 |
Cytomx Therapeutics, Inc. |
Anticuerpos multiespecíficos, anticuerpos activables multiespecíficos y métodos para usar los mismos
|
WO2015017807A1
(en)
*
|
2013-08-01 |
2015-02-05 |
University Of Georgia Research Foundation, Inc. |
Liposomal formulations for the treatment of bacterial infections
|
PE20211093A1
(es)
|
2013-08-02 |
2021-06-14 |
Pfizer |
Anticuerpos anti-cxcr4 y conjugados de anticuerpo y farmaco
|
MX2016001854A
(es)
|
2013-08-12 |
2016-09-06 |
Genentech Inc |
Composiciones y metodo para tratar condiciones asociadas con el complemento.
|
WO2015023851A1
(en)
|
2013-08-14 |
2015-02-19 |
The Governing Council Of The University Of Toronto |
Antibodies against frizzled proteins and methods of use thereof
|
WO2015031536A1
(en)
*
|
2013-08-27 |
2015-03-05 |
Northeastern University |
Nanoparticle drug delivery system and method of treating cancer and neurotrauma
|
PL3041958T3
(pl)
|
2013-09-04 |
2020-11-02 |
Cold Spring Harbor Laboratory |
Redukcja rozpadu mRNA mediowanego sekwencjami nonsensownymi
|
WO2015035231A1
(en)
|
2013-09-05 |
2015-03-12 |
Sarepta Therapeutics, Inc. |
Antisense-induced exon2 inclusion in acid alpha-glucosidase
|
US20150065381A1
(en)
|
2013-09-05 |
2015-03-05 |
International Aids Vaccine Initiative |
Methods of identifying novel hiv-1 immunogens
|
AR097648A1
(es)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
|
US20160228364A1
(en)
*
|
2013-09-16 |
2016-08-11 |
Glycomine, Inc. |
Pharmaceutical preparation of carbohydrates for therapeutic use
|
DE102013015334A1
(de)
*
|
2013-09-17 |
2015-03-19 |
Fresenius Medical Care Deutschland Gmbh |
Magnesium-Liposomen-Komplexe
|
US10036020B2
(en)
|
2013-09-19 |
2018-07-31 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Compositions and methods for inhibiting JC virus (JCV)
|
MX2016003957A
(es)
|
2013-09-25 |
2017-02-02 |
Cytomx Therapeutics Inc |
Substratos de metaloproteinasas de matriz y otras porciones escindibles y metodos para usar los mismos.
|
US10259875B2
(en)
|
2013-10-01 |
2019-04-16 |
Mayo Foundation For Medical Education And Research |
Methods for treating cancer in patients with elevated levels of BIM
|
MX2016004230A
(es)
|
2013-10-02 |
2016-10-21 |
Alnylam Pharmaceuticals Inc |
Composiciones y metodos para inhibir la expresion del gen lect2.
|
SG10201910929QA
(en)
|
2013-10-04 |
2020-01-30 |
Alnylam Pharmaceuticals Inc |
Compositions and methods for inhibiting expression of the alas1 gene
|
EP2873423B1
(en)
|
2013-10-07 |
2017-05-31 |
International Aids Vaccine Initiative |
Soluble hiv-1 envelope glycoprotein trimers
|
US20160264648A1
(en)
|
2013-11-06 |
2016-09-15 |
Osaka University |
Antibody having broad neutralization activity against group 1 influenza a viruses
|
WO2015087187A1
(en)
|
2013-12-10 |
2015-06-18 |
Rinat Neuroscience Corp. |
Anti-sclerostin antibodies
|
US20160333063A1
(en)
|
2013-12-13 |
2016-11-17 |
The General Hospital Corporation |
Soluble high molecular weight (hmw) tau species and applications thereof
|
JP2017500319A
(ja)
|
2013-12-20 |
2017-01-05 |
ギリアード カリストガ エルエルシー |
(s)−2−(1−(9h−プリン−6−イルアミノ)プロピル)−5−フルオロ−3−フェニルキナゾリン−4(3h)−オンの塩酸塩の多形形態
|
PL3083630T3
(pl)
|
2013-12-20 |
2020-02-28 |
Gilead Calistoga Llc |
Sposoby otrzymywania inhibitorów 3-kinazy fosfatydyloinozytolu
|
CN106102725A
(zh)
|
2014-01-14 |
2016-11-09 |
约翰斯·霍普金斯大学 |
包封选择性atp抑制剂的环糊精组合物及其应用
|
CN105873949A
(zh)
|
2014-01-31 |
2016-08-17 |
勃林格殷格翰国际有限公司 |
新的抗baff抗体
|
JP6835586B2
(ja)
|
2014-01-31 |
2021-02-24 |
シトムクス セラピューティクス,インコーポレイティド |
マトリプターゼ及びu‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法
|
WO2015116902A1
(en)
|
2014-01-31 |
2015-08-06 |
Genentech, Inc. |
G-protein coupled receptors in hedgehog signaling
|
JP6736467B2
(ja)
|
2014-02-04 |
2020-08-05 |
ジェネンテック, インコーポレイテッド |
平滑化変異体及びその使用方法
|
EP3110974A4
(en)
|
2014-02-24 |
2018-01-24 |
Celgene Corporation |
Methods of using an activator of cereblon for neural cell expansion and the treatment of central nervous system disorders
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
NZ711451A
(en)
|
2014-03-07 |
2016-05-27 |
Alexion Pharma Inc |
Anti-c5 antibodies having improved pharmacokinetics
|
AU2015231164B2
(en)
|
2014-03-19 |
2020-04-09 |
Dana-Farber Cancer Institute, Inc. |
Immunogenetic restriction on elicitation of antibodies
|
CN106456759A
(zh)
|
2014-03-21 |
2017-02-22 |
泰华制药国际有限公司 |
针对降钙素基因相关肽的拮抗剂抗体及其使用方法
|
CA2939246A1
(en)
|
2014-03-27 |
2015-10-01 |
Genentech, Inc. |
Methods for diagnosing and treating inflammatory bowel disease
|
KR20160132496A
(ko)
|
2014-04-03 |
2016-11-18 |
인빅터스 온콜로지 피비티. 엘티디. |
초분자 조합 치료제
|
WO2015164865A1
(en)
|
2014-04-25 |
2015-10-29 |
Dana-Farber Cancer Institute, Inc. |
Middle east respiratory syndrome coronavirus neutralizing antibodies and methods of use thereof
|
WO2015168474A1
(en)
|
2014-04-30 |
2015-11-05 |
President And Fellows Of Harvard College |
Fusion proteins for treating cancer and related methods
|
AU2015253422B2
(en)
|
2014-04-30 |
2020-09-03 |
Abbvie Stemcentrx Llc |
Anti-PTK7 antibody-drug conjugates
|
WO2015171918A2
(en)
|
2014-05-07 |
2015-11-12 |
Louisiana State University And Agricultural And Mechanical College |
Compositions and uses for treatment thereof
|
EP3143043B1
(en)
|
2014-05-16 |
2022-12-14 |
Pfizer Inc. |
Bispecific antibodies with engineered ch1-cl interfaces
|
EA028614B1
(ru)
|
2014-05-22 |
2017-12-29 |
Общество С Ограниченной Ответственностью "Русские Фармацевтические Технологии" |
Селективные ингибиторы, нарушающие взаимодействие рецептора фактора роста фибробластов и frs2, для профилактики и лечения рака
|
WO2015179654A1
(en)
|
2014-05-22 |
2015-11-26 |
Mayo Foundation For Medical Education And Research |
Distinguishing antagonistic and agonistic anti b7-h1 antibodies
|
ES2905777T3
(es)
|
2014-05-30 |
2022-04-12 |
Shanghai Henlius Biotech Inc |
Anticuerpos anti-receptor del factor de crecimiento epidérmico (EGFR)
|
ES2950789T3
(es)
|
2014-06-10 |
2023-10-13 |
Amgen Inc |
Polipéptidos de apelina
|
BR112016028750A2
(pt)
|
2014-06-11 |
2017-11-14 |
Gilead Sciences Inc |
?métodos para tratar, prevenir, ou melhorar pelo menos um sintoma associado e para diagnosticar e monitorar insuficiência cardíaca ou fibrilação atrial, inibidor da lisil oxidase ativa ou proteína lisil tipo oxidase, e, composição?
|
NZ726360A
(en)
|
2014-06-13 |
2018-04-27 |
Gilead Sciences Inc |
Phosphatidylinositol 3-kinase inhibitors
|
TWI695011B
(zh)
|
2014-06-18 |
2020-06-01 |
美商梅爾莎納醫療公司 |
抗her2表位之單株抗體及其使用之方法
|
CN114057857A
(zh)
|
2014-06-20 |
2022-02-18 |
豪夫迈·罗氏有限公司 |
基于chagasin的支架组合物、方法和应用
|
CA2985344A1
(en)
|
2014-06-26 |
2015-12-30 |
The Trustees Of Columbia University In The City Of New York |
Inhibition of serotonin expression in gut enteroendocrine cells results in conversion to insulin-positive cells
|
WO2016014148A1
(en)
|
2014-07-23 |
2016-01-28 |
Mayo Foundation For Medical Education And Research |
Targeting dna-pkcs and b7-h1 to treat cancer
|
EP3172235A2
(en)
|
2014-07-25 |
2017-05-31 |
Cytomx Therapeutics Inc. |
Anti-cd3 antibodies, activatable anti-cd3 antibodies, multispecific anti-cd3 antibodies, multispecific activatable anti-cd3 antibodies, and methods of using the same
|
EP3174901B1
(en)
|
2014-07-31 |
2019-06-26 |
Amgen Research (Munich) GmbH |
Optimized cross-species specific bispecific single chain antibody constructs
|
UY36245A
(es)
|
2014-07-31 |
2016-01-29 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
WO2016020799A1
(en)
|
2014-08-06 |
2016-02-11 |
Rinat Neuroscience Corp. |
Methods for reducing ldl-cholesterol
|
EP3193928A1
(en)
|
2014-08-06 |
2017-07-26 |
Rinat Neuroscience Corp. |
Methods for reducing ldl-cholesterol
|
WO2016033424A1
(en)
|
2014-08-29 |
2016-03-03 |
Genzyme Corporation |
Methods for the prevention and treatment of major adverse cardiovascular events using compounds that modulate apolipoprotein b
|
WO2016034968A1
(en)
|
2014-09-02 |
2016-03-10 |
Pfizer Inc. |
Therapeutic antibody
|
EP3197492A1
(en)
|
2014-09-23 |
2017-08-02 |
Pfizer Inc |
Treatment with anti-pcsk9 antibodies
|
CN107250159A
(zh)
|
2014-10-03 |
2017-10-13 |
达纳-法伯癌症研究所公司 |
糖皮质激素诱导的肿瘤坏死因子受体(gitr)抗体及其使用方法
|
EP3699196A1
(en)
|
2014-10-06 |
2020-08-26 |
Dana Farber Cancer Institute, Inc. |
Humanized cc chemokine receptor 4 (ccr4) antibodies and methods of use thereof
|
GB201417589D0
(en)
|
2014-10-06 |
2014-11-19 |
Cantab Biopharmaceuticals Patents Ltd |
Pharmaceutical Formulations
|
AU2015338974B2
(en)
|
2014-10-31 |
2021-08-26 |
Oncomed Pharmaceuticals, Inc. |
Combination therapy for treatment of disease
|
WO2016077566A1
(en)
|
2014-11-12 |
2016-05-19 |
Research Institute At Nationwide Children's Hospital |
Modulation of alternative mdm2 splicing
|
US9879087B2
(en)
|
2014-11-12 |
2018-01-30 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
WO2016077526A1
(en)
|
2014-11-12 |
2016-05-19 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
EP3226889A4
(en)
|
2014-11-19 |
2018-11-21 |
The Trustees of Columbia University in the City of New York |
Osteocalcin as a treatment for frailty associated with aging
|
MX2017007231A
(es)
|
2014-12-03 |
2017-11-08 |
Genentech Inc |
Conjugados de rifamicina y anticuerpos contra el staphylococcuss aureus y usos de estos.
|
BR112017011325A2
(pt)
|
2014-12-03 |
2020-07-21 |
Genentech, Inc. |
?composto de conjugado anticorpo?antibiótico, composição, método de tratamento de uma infecção, método para matar staph aureus, processo para produzir o conjugado, kit para o tratamento de uma infecção, intermediários antibiótico-ligante e ligante-droga?
|
US10072070B2
(en)
|
2014-12-05 |
2018-09-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Potent anti-influenza A neuraminidase subtype N1 antibody
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
EP3333191B1
(en)
|
2014-12-11 |
2020-09-09 |
Pierre Fabre Medicament |
Anti-c10orf54 antibodies and uses thereof
|
TW201702218A
(zh)
|
2014-12-12 |
2017-01-16 |
美國杰克森實驗室 |
關於治療癌症、自體免疫疾病及神經退化性疾病之組合物及方法
|
WO2016100380A1
(en)
|
2014-12-15 |
2016-06-23 |
The Johns Hopkins University |
Sunitinib formulations and methods for use thereof in treatment of glaucoma
|
AU2015364508A1
(en)
|
2014-12-18 |
2017-07-06 |
Alnylam Pharmaceuticals, Inc. |
ReversirTM compounds
|
EP3247386A4
(en)
|
2015-01-20 |
2018-10-03 |
The Children's Medical Center Corporation |
Anti-net compounds for treating and preventing fibrosis and for facilitating wound healing
|
MA41374A
(fr)
|
2015-01-20 |
2017-11-28 |
Cytomx Therapeutics Inc |
Substrats clivables par métalloprotéase matricielle et clivables par sérine protéase et procédés d'utilisation de ceux-ci
|
WO2016123125A1
(en)
|
2015-01-27 |
2016-08-04 |
The Johns Hopkins University |
Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces
|
WO2016123329A2
(en)
|
2015-01-28 |
2016-08-04 |
Genentech, Inc. |
Gene expression markers and treatment of multiple sclerosis
|
EP3250588A1
(en)
|
2015-01-29 |
2017-12-06 |
Board of Trustees of Michigan State University |
Cryptic polypeptides and uses thereof
|
CA2976912A1
(en)
*
|
2015-02-17 |
2016-08-25 |
Mallinckrodt Llc |
Modified docetaxel liposome formulations and uses thereof
|
WO2016134333A1
(en)
|
2015-02-19 |
2016-08-25 |
Compugen Ltd. |
Anti-pvrig antibodies and methods of use
|
DK3259597T3
(da)
|
2015-02-19 |
2022-05-09 |
Compugen Ltd |
Pvrig-polypeptider og fremgangsmåder til behandling
|
KR20170120601A
(ko)
|
2015-02-26 |
2017-10-31 |
제넨테크, 인크. |
인테그린 베타7 길항제 및 크론병을 치료하는 방법
|
CN114504651A
(zh)
|
2015-03-03 |
2022-05-17 |
科马布有限公司 |
抗体、用途和方法
|
US9895313B2
(en)
|
2015-03-03 |
2018-02-20 |
Cureport, Inc. |
Combination liposomal pharmaceutical formulations
|
CN107530291A
(zh)
*
|
2015-03-03 |
2018-01-02 |
奎尔波特股份有限公司 |
双重负载的脂质体药物制剂
|
AU2016233495B2
(en)
|
2015-03-13 |
2022-02-24 |
Cytomx Therapeutics, Inc |
Anti-PDL1 antibodies, activatable anti-PDL1 antibodies, and methods of use thereof
|
US20180071253A1
(en)
|
2015-03-17 |
2018-03-15 |
Lipomedix Pharmaceuticals Ltd. |
Methods for the treatment of bladder cancer
|
MA41795A
(fr)
|
2015-03-18 |
2018-01-23 |
Sarepta Therapeutics Inc |
Exclusion d'un exon induite par des composés antisens dans la myostatine
|
US10174292B2
(en)
|
2015-03-20 |
2019-01-08 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
US9931394B2
(en)
|
2015-03-23 |
2018-04-03 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
US9758575B2
(en)
|
2015-04-06 |
2017-09-12 |
Yung Shin Pharmaceutical Industrial Co. Ltd. |
Antibodies which specifically bind to canine vascular endothelial growth factor and uses thereof
|
CN107750253B
(zh)
|
2015-04-08 |
2022-10-04 |
达纳-法伯癌症研究所公司 |
人源化流感单克隆抗体及其使用方法
|
TWI703159B
(zh)
|
2015-04-13 |
2020-09-01 |
美商輝瑞股份有限公司 |
Bcma特異性治療性抗體及其用途
|
SG10201909308XA
(en)
|
2015-04-17 |
2019-11-28 |
Amgen Res Munich Gmbh |
Bispecific antibody constructs for cdh3 and cd3
|
JP6956639B2
(ja)
|
2015-05-01 |
2021-11-02 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
抗ccr4抗体を用いてサイトカイン発現を媒介する方法
|
EA201792414A1
(ru)
|
2015-05-04 |
2018-06-29 |
Сайтомкс Терапьютикс, Инк. |
Антитела против cd166, активируемые антитела против cd166 и способы их применения
|
LT3292149T
(lt)
|
2015-05-04 |
2022-03-10 |
Cytomx Therapeutics, Inc. |
Aktyvinami antikūnai prieš cd71 ir jų naudojimo būdai
|
EP3292151A1
(en)
|
2015-05-04 |
2018-03-14 |
Cytomx Therapeutics Inc. |
Anti-itga3 antibodies, activatable anti-itga3 antibodies, and methods of use thereof
|
US20180104331A1
(en)
|
2015-05-11 |
2018-04-19 |
The Johns Hopkins University |
Autoimmune antibodies for use in inhibiting cancer cell growth
|
WO2016180986A1
(en)
|
2015-05-14 |
2016-11-17 |
Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii (Cnic) |
Mirna compositions for the treatment of mature b-cell neoplasms
|
US11318131B2
(en)
|
2015-05-18 |
2022-05-03 |
Ipsen Biopharm Ltd. |
Nanoliposomal irinotecan for use in treating small cell lung cancer
|
CA2984638A1
(en)
|
2015-05-29 |
2016-12-08 |
Genentech, Inc. |
Pd-l1 promoter methylation in cancer
|
EP3302497A4
(en)
|
2015-06-01 |
2019-01-16 |
Sarepta Therapeutics, Inc. |
EXCLUSION OF EXON INDUCED PAT TECHNOLOGY ANTISENSE IN COLLAGEN TYPE VII
|
AU2016274126A1
(en)
|
2015-06-10 |
2018-01-18 |
Elysium Health, Inc. |
Nicotinamide riboside and pterostilbene compositions and methods for treatment of skin disorders
|
JP6768722B2
(ja)
|
2015-07-02 |
2020-10-14 |
大塚製薬株式会社 |
凍結乾燥医薬組成物
|
CA2991980A1
(en)
|
2015-07-13 |
2017-01-19 |
Compugen Ltd. |
Hide1 compositions and methods
|
KR20180040138A
(ko)
|
2015-07-13 |
2018-04-19 |
싸이톰스 테라퓨틱스, 인크. |
항pd-1 항체, 활성화 가능한 항pd-1 항체, 및 이들의 사용 방법
|
CA2989970A1
(en)
|
2015-07-17 |
2017-01-26 |
Alnylam Pharmaceuticals, Inc. |
Multi-targeted single entity conjugates
|
EP3325516B1
(en)
|
2015-07-21 |
2021-12-15 |
Takeda Pharmaceutical Company Limited |
A monoclonal antibody inhibitor of factor xiia
|
PL3328886T3
(pl)
|
2015-07-29 |
2021-02-08 |
Allergan, Inc. |
Przeciwciała ang-2 o wyłącznie ciężkim łańcuchu
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
WO2017030909A1
(en)
|
2015-08-14 |
2017-02-23 |
Allergan, Inc. |
Heavy chain only antibodies to pdgf
|
JP7042739B2
(ja)
|
2015-08-20 |
2022-03-28 |
イプセン バイオファーム リミティド |
癌処置のためのリポソーム型イリノテカン及びparp阻害薬を使用する併用療法
|
TW202243677A
(zh)
|
2015-08-21 |
2022-11-16 |
英商益普生生物製藥有限公司 |
使用包含微脂伊立替康(irinotecan)及奧沙利鉑(oxaliplatin)之組合療法治療轉移性胰臟癌的方法
|
WO2017040566A1
(en)
|
2015-09-01 |
2017-03-09 |
Boehringer Ingelheim International Gmbh |
Use of anti-cd40 antibodies for treatment of lupus nephritis
|
TW201718857A
(zh)
|
2015-09-14 |
2017-06-01 |
艾爾妮蘭製藥公司 |
用於抑制alas1基因表現之組合物及方法
|
IL258121B2
(en)
|
2015-09-15 |
2024-01-01 |
Scholar Rock Inc |
Antipro/latent myostatin antibodies and their uses
|
TWI799366B
(zh)
|
2015-09-15 |
2023-04-21 |
美商建南德克公司 |
胱胺酸結骨架平臺
|
CN109071644B
(zh)
|
2015-09-23 |
2023-09-19 |
昂考梅德药品有限公司 |
治疗癌症的方法和组合物
|
US10954300B2
(en)
|
2015-09-28 |
2021-03-23 |
The Trustees Of Columbia University In The City Of New York |
Use of pentoxifylline with immune checkpoint-blockade therapies for the treatment of melanoma
|
WO2017055966A1
(en)
|
2015-10-01 |
2017-04-06 |
Pfizer Inc. |
Low viscosity antibody compositions
|
CN108431038A
(zh)
|
2015-10-06 |
2018-08-21 |
豪夫迈·罗氏有限公司 |
治疗多发性硬化的方法
|
MA45819A
(fr)
|
2015-10-09 |
2018-08-15 |
Sarepta Therapeutics Inc |
Compositions et méthodes pour traiter la dystrophie musculaire de duchenne et troubles associés
|
GB201518170D0
(en)
|
2015-10-14 |
2015-11-25 |
Cantab Biopharmaceuticals Patents Ltd |
Colloidal particles for subcutaneous administration with intravenous administration of therapeutic agent
|
GB201518171D0
(en)
|
2015-10-14 |
2015-11-25 |
Cantab Biopharmaceuticals Patents Ltd |
Colloidal particles for topical administration with therapeutic agent
|
GB201518172D0
(en)
|
2015-10-14 |
2015-11-25 |
Cantab Biopharmaceuticals Patents Ltd |
Colloidal particles for use in medicine
|
WO2017066714A1
(en)
|
2015-10-16 |
2017-04-20 |
Compugen Ltd. |
Anti-vsig1 antibodies and drug conjugates
|
MA42991A
(fr)
|
2015-10-16 |
2018-08-22 |
Ipsen Biopharm Ltd |
Stabilisation de compositions pharmaceutiques de camptothécine
|
WO2017075037A1
(en)
|
2015-10-27 |
2017-05-04 |
Scholar Rock, Inc. |
Primed growth factors and uses thereof
|
WO2017075045A2
(en)
|
2015-10-30 |
2017-05-04 |
Mayo Foundation For Medical Education And Research |
Antibodies to b7-h1
|
KR102162324B1
(ko)
|
2015-10-30 |
2020-10-07 |
제넨테크, 인크. |
항-HtrA1 항체 및 이의 사용 방법
|
WO2017075670A1
(en)
|
2015-11-05 |
2017-05-11 |
Children's Hospital Los Angeles |
"mobilizing leukemia cells"
|
WO2017079563A1
(en)
|
2015-11-06 |
2017-05-11 |
The Johns Hopkins University |
Methods of treating liver fibrosis by administering 3-bromopyruvate
|
WO2017083403A1
(en)
|
2015-11-10 |
2017-05-18 |
Children's Research Institute, Children's National Medical Center |
Echinomycin formulation, method of making and method of use thereof
|
CN116217729A
(zh)
|
2015-11-12 |
2023-06-06 |
思进公司 |
聚糖相互作用化合物及使用方法
|
KR20180102069A
(ko)
|
2015-11-12 |
2018-09-14 |
그레이버그 비젼, 인크. |
요법을 위한 응집성 마이크로입자
|
TWI727380B
(zh)
|
2015-11-30 |
2021-05-11 |
美商輝瑞股份有限公司 |
位點專一性her2抗體藥物共軛體
|
CA2949033A1
(en)
|
2015-11-30 |
2017-05-30 |
Pfizer Inc. |
Antibodies and antibody fragments for site-specific conjugation
|
KR20180100122A
(ko)
|
2015-12-02 |
2018-09-07 |
주식회사 에스티사이언스 |
당화된 btla(b- 및 t-림프구 약화인자)에 특이적인 항체
|
ES2861449T3
(es)
|
2015-12-02 |
2021-10-06 |
Stcube & Co Inc |
Anticuerpos y moléculas que se unen inmunoespecíficamente a BTN1A1 y los usos terapéuticos de los mismos
|
US20190307857A1
(en)
|
2015-12-09 |
2019-10-10 |
Modernatx, Inc. |
MODIFIED mRNA ENCODING A URIDINE DIPHOPSPHATE GLUCURONOSYL TRANSFERASE AND USES THEREOF
|
US10548844B2
(en)
|
2015-12-14 |
2020-02-04 |
Massachusetts Institute Of Technology |
pH-responsive mucoadhesive polymeric encapsulated microorganisms
|
WO2017106630A1
(en)
|
2015-12-18 |
2017-06-22 |
The General Hospital Corporation |
Polyacetal polymers, conjugates, particles and uses thereof
|
JPWO2017110772A1
(ja)
|
2015-12-21 |
2018-09-13 |
富士フイルム株式会社 |
リポソーム及びリポソーム組成物
|
US11534451B2
(en)
|
2015-12-23 |
2022-12-27 |
Repluca Pty Ltd |
Nucleic acid oligomers and uses therefor
|
WO2017117218A1
(en)
|
2015-12-30 |
2017-07-06 |
Momenta Pharmaceuticals, Inc. |
Methods related to biologics
|
MX2018008369A
(es)
|
2016-01-08 |
2019-05-15 |
Scholar Rock Inc |
Anticuerpos de anti-miostatina pro/latente y metodo de uso de los mismos.
|
US20210206818A1
(en)
|
2016-01-22 |
2021-07-08 |
Modernatx, Inc. |
Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
|
JOP20170017B1
(ar)
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
تركيب صيدلي يتضمن تركيبات جسم مضاد ثنائي الاختصاص
|
UA126656C2
(uk)
|
2016-02-03 |
2023-01-11 |
Емджен Рісерч (Мюнік) Гмбх |
Біспецифічна конструкція антитіла до psma і cd3, яке залучають t-клітини
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
MA43955B1
(fr)
|
2016-02-03 |
2022-02-28 |
Amgen Inc |
Anticorps anti-bcma et anti-cd3 bispécifiques de format bite
|
CN109071625A
(zh)
|
2016-02-04 |
2018-12-21 |
柯瑞斯公司 |
平滑化突变体和其使用方法
|
AU2017229232B2
(en)
*
|
2016-03-07 |
2022-12-15 |
Memorial Sloan Kettering Cancer Center |
Bone marrow-, reticuloendothelial system-, and/or lymph node-targeted radiolabeled liposomes and methods of their diagnostic and therapeutic use
|
WO2017156032A1
(en)
|
2016-03-07 |
2017-09-14 |
Charlestonpharma, Llc |
Anti-nucleolin antibodies
|
MX2018010948A
(es)
|
2016-03-11 |
2019-06-20 |
Scholar Rock Inc |
INMUNOGLOBULINAS DE ENLACE A TGFß1 Y USOS DE LAS MISMAS.
|
WO2017157305A1
(en)
|
2016-03-15 |
2017-09-21 |
Generon (Shanghai) Corporation Ltd. |
Multispecific fab fusion proteins and use thereof
|
EP3445405A4
(en)
|
2016-04-18 |
2019-12-18 |
Sarepta Therapeutics, Inc. |
ANTISENSE OLIGOMERS AND METHOD FOR USE THEREOF TO TREAT DISEASES RELATING TO THE ACID ALPHA GLUCOSIDASE GENE
|
US10973748B2
(en)
|
2016-04-21 |
2021-04-13 |
Versitech Limited |
Compositions and methods for lightening skin and reducing hyperpigmentation
|
DK3468997T3
(da)
|
2016-06-08 |
2023-10-02 |
Xencor Inc |
Behandling af IgG4-relaterede sygdomme med anti-CD9-antistoffer med tværbinding til CD32B
|
ITUA20164630A1
(it)
|
2016-06-23 |
2017-12-23 |
Paolo Blasi |
Adiuvanti farmacologici per la termoablazione tumorale
|
US20200306350A1
(en)
|
2016-06-27 |
2020-10-01 |
Alexion Pharmaceuticals, Inc. |
Methods for treating hypophosphatasia in children and adolescents
|
US11246832B2
(en)
|
2016-06-28 |
2022-02-15 |
Verily Life Sciences Llc |
Serial filtration to generate small cholesterol-containing liposomes
|
KR102534568B1
(ko)
|
2016-07-22 |
2023-05-18 |
다나-파버 캔서 인스티튜트 인크. |
글루코코르티코이드-유도된 종양 괴사 인자 수용체 (gitr) 항체 및 이의 이용 방법
|
RU2757394C2
(ru)
|
2016-08-03 |
2021-10-14 |
Нексткьюр, Инк. |
Композиции и способы для модуляции передачи сигнала lair
|
KR20190035752A
(ko)
|
2016-08-03 |
2019-04-03 |
사이머베이 쎄라퓨틱스, 인코퍼레이티드 |
염증성 위장 질환 또는 위장 상태를 치료하기 위한 옥시메틸렌 아릴 화합물
|
TWI754659B
(zh)
|
2016-08-08 |
2022-02-11 |
台灣微脂體股份有限公司 |
用於製備含有弱酸性劑之微脂體組合物的傳輸載體、方法及套組
|
AU2017321973A1
(en)
|
2016-09-02 |
2019-03-07 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of treating B cell disorders
|
MX2019002696A
(es)
|
2016-09-06 |
2019-09-27 |
Dana Farber Cancer Inst Inc |
Metodos para tratar o prevenir una infeccion del virus del zika.
|
TW201825511A
(zh)
|
2016-09-09 |
2018-07-16 |
美商艾斯合顧問有限公司 |
表現免疫檢查點調節子的溶瘤病毒
|
WO2018049275A1
(en)
|
2016-09-09 |
2018-03-15 |
Genentech, Inc. |
Selective peptide inhibitors of frizzled
|
US11236177B2
(en)
|
2016-09-14 |
2022-02-01 |
The Trustees Of The University Of Pennsylvania |
Proximity-based sortase-mediated protein purification and ligation
|
WO2018052818A1
(en)
|
2016-09-16 |
2018-03-22 |
Henlix, Inc. |
Anti-pd-1 antibodies
|
CN109952314A
(zh)
|
2016-09-23 |
2019-06-28 |
泰瓦制药国际有限公司 |
治疗难治性偏头痛
|
EP3515488A1
(en)
|
2016-09-23 |
2019-07-31 |
Teva Pharmaceuticals International GmbH |
Treating cluster headache
|
CA3042015A1
(en)
|
2016-10-26 |
2018-05-03 |
Modernatx, Inc. |
Messenger ribonucleic acids for enhancing immune responses and methods of use thereof
|
MX2019004783A
(es)
|
2016-11-02 |
2019-08-12 |
Ipsen Biopharm Ltd |
Tratamiento de cancer gastrico usando terapias de combinacion que comprenden irinotecan liposomico oxaliplatino, 5-fluoruracilo (y leucovorina).
|
WO2018083248A1
(en)
|
2016-11-03 |
2018-05-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
CA3040812A1
(en)
|
2016-11-04 |
2018-05-11 |
Novimmune Sa |
Anti-cd19 antibodies and methods of use thereof
|
JP2020500020A
(ja)
|
2016-11-14 |
2020-01-09 |
ノバルティス アーゲー |
融合誘導性タンパク質minionに関連する組成物、方法、および治療上の使用
|
US11401330B2
(en)
|
2016-11-17 |
2022-08-02 |
Seagen Inc. |
Glycan-interacting compounds and methods of use
|
WO2018106738A1
(en)
|
2016-12-05 |
2018-06-14 |
Massachusetts Institute Of Technology |
Brush-arm star polymers, conjugates and particles, and uses thereof
|
US10772926B2
(en)
|
2016-12-16 |
2020-09-15 |
Nutragen Health Innovations, Inc. |
Natural drugs for the treatment of inflammation and melanoma
|
PE20191501A1
(es)
|
2016-12-16 |
2019-10-22 |
Pfizer |
Agonistas receptores de glp-1 y sus usos de los mismos
|
WO2018129395A1
(en)
|
2017-01-06 |
2018-07-12 |
Scholar Rock, Inc. |
Methods for treating metabolic diseases by inhibiting myostatin activation
|
DK3565592T3
(da)
|
2017-01-06 |
2023-05-01 |
Scholar Rock Inc |
Behandling af stofskiftesygdomme ved inhibering af myostatinaktivering
|
WO2018129329A1
(en)
|
2017-01-06 |
2018-07-12 |
Scholar Rock, Inc. |
ISOFORM-SPECIFIC, CONTEXT-PERMISSIVE TGFβ1 INHIBITORS AND USE THEREOF
|
CN110430894A
(zh)
|
2017-02-01 |
2019-11-08 |
莫得纳特斯公司 |
编码活化致癌基因突变肽的免疫调节治疗性mrna组合物
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
WO2018152496A1
(en)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions and methods for the diagnosis and treatment of zika virus infection
|
AU2018226646A1
(en)
|
2017-03-03 |
2019-09-19 |
Rinat Neuroscience Corp. |
Anti-GITR antibodies and methods of use thereof
|
JP2020510671A
(ja)
|
2017-03-03 |
2020-04-09 |
シアトル ジェネティックス, インコーポレイテッド |
グリカン相互作用化合物および使用の方法
|
KR20190134654A
(ko)
|
2017-03-09 |
2019-12-04 |
싸이톰스 테라퓨틱스, 인크. |
Cd147 항체, 활성화가능한 cd147 항체, 그리고 이를 만들고, 이용하는 방법
|
EP3601350A1
(en)
|
2017-03-27 |
2020-02-05 |
Boehringer Ingelheim International GmbH |
Anti il-36r antibodies combination therapy
|
US11359200B2
(en)
|
2017-04-09 |
2022-06-14 |
The Cleveland Clinic Foundation |
Cancer treatment by MALAT1 inhibition
|
JP2020512825A
(ja)
|
2017-04-12 |
2020-04-30 |
ファイザー・インク |
条件的親和性を有する抗体およびその使用の方法
|
WO2018191548A2
(en)
|
2017-04-14 |
2018-10-18 |
Kodiak Sciences Inc. |
Complement factor d antagonist antibodies and conjugates thereof
|
AU2018255244A1
(en)
|
2017-04-21 |
2019-10-31 |
Mellitus, Llc |
Methods and antibodies for diabetes-related applications
|
EP3615569A1
(en)
|
2017-04-25 |
2020-03-04 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis and treatment of epstein barr virus infection
|
US11318190B2
(en)
|
2017-05-05 |
2022-05-03 |
United States Government As Represented By The Department Of Veterans Affairs |
Methods and compositions for treating liver disease
|
AU2018261951A1
(en)
|
2017-05-05 |
2019-10-31 |
Amgen Inc. |
Pharmaceutical composition comprising bispecific antibody constructs for improved storage and administration
|
MX2019013363A
(es)
|
2017-05-10 |
2020-01-13 |
Graybug Vision Inc |
Microparticulas de liberacion extendida y suspensiones de las mismas para terapia medica.
|
WO2018209288A1
(en)
|
2017-05-12 |
2018-11-15 |
Massachusetts Institute Of Technology |
Argonaute protein-double stranded rna complexes and uses related thereto
|
KR20200006985A
(ko)
|
2017-05-12 |
2020-01-21 |
오거스타 유니버시티 리서치 인스티튜트, 인크. |
인간 알파 태아단백-특이적 t 세포 수용체 및 이의 용도
|
EP3630167A1
(en)
|
2017-05-26 |
2020-04-08 |
NovImmune SA |
Anti-cd47 x anti-mesothelin antibodies and methods of use thereof
|
AU2018277838A1
(en)
|
2017-05-31 |
2019-12-19 |
Stcube & Co., Inc. |
Antibodies and molecules that immunospecifically bind to BTN1A1 and the therapeutic uses thereof
|
KR20200024158A
(ko)
|
2017-05-31 |
2020-03-06 |
주식회사 에스티큐브앤컴퍼니 |
Btn1a1에 면역특이적으로 결합하는 항체 및 분자를 사용하여 암을 치료하는 방법
|
US11168144B2
(en)
|
2017-06-01 |
2021-11-09 |
Cytomx Therapeutics, Inc. |
Activatable anti-PDL1 antibodies, and methods of use thereof
|
JP2020522562A
(ja)
|
2017-06-06 |
2020-07-30 |
ストキューブ アンド シーオー., インコーポレイテッド |
Btn1a1又はbtn1a1リガンドに結合する抗体及び分子を用いて癌を治療する方法
|
GB201710838D0
(en)
|
2017-07-05 |
2017-08-16 |
Ucl Business Plc |
Bispecific antibodies
|
US10590416B2
(en)
|
2017-07-06 |
2020-03-17 |
Arrowhead Pharmaceuticals, Inc. |
RNAi agents for inhibiting expression of alpha-ENaC and methods of use
|
JP2020527558A
(ja)
|
2017-07-13 |
2020-09-10 |
マサチューセッツ インスティテュート オブ テクノロジー |
シナプス機能を増強するためのhdac2−sp3複合体の標的化
|
JP2020531045A
(ja)
|
2017-07-14 |
2020-11-05 |
シートムエックス セラピューティクス,インコーポレイテッド |
抗cd166抗体およびその使用
|
EP3655430A1
(en)
|
2017-07-19 |
2020-05-27 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Antibodies and methods for the diagnosis and treatment of hepatitis b virus infection
|
JP2020530554A
(ja)
|
2017-07-20 |
2020-10-22 |
シートムエックス セラピューティクス,インコーポレイテッド |
活性化抗体の特性を定性的および/または定量的に分析する方法およびその使用
|
MA49634A
(fr)
|
2017-07-21 |
2020-05-27 |
Modernatx Inc |
Arnm modifié codant pour une propionyl-coa-carboxylase et utilisations associées
|
WO2019016784A1
(en)
|
2017-07-21 |
2019-01-24 |
Universidade De Coimbra |
ANTI-NUCLEOLIN ANTIBODIES
|
MA49684A
(fr)
|
2017-07-24 |
2020-06-03 |
Modernatx Inc |
Arnm modifié codant une glucose-6-phosphatase et utilisations associées
|
JP7079844B2
(ja)
|
2017-07-27 |
2022-06-02 |
アレクシオン ファーマシューティカルズ, インコーポレイテッド |
高濃度抗c5抗体製剤
|
WO2019023661A1
(en)
|
2017-07-28 |
2019-01-31 |
Scholar Rock, Inc. |
SPECIFIC INHIBITORS OF TGF-BETA 1 LTBP COMPLEX AND USES THEREOF
|
JP2020529409A
(ja)
|
2017-08-03 |
2020-10-08 |
大塚製薬株式会社 |
薬物化合物およびその精製方法
|
US11135187B2
(en)
|
2017-08-22 |
2021-10-05 |
National Institutes Of Health (Nih) |
Compositions and methods for treating diabetic retinopathy
|
BR112020004231A2
(pt)
|
2017-08-30 |
2020-09-08 |
Cytomx Therapeutics, Inc. |
anticorpos anti-cd166 ativáveis e métodos de uso dos mesmos
|
AU2018330180A1
(en)
|
2017-09-07 |
2020-03-19 |
Augusta University Research Institute, Inc. |
Antibodies to programmed cell death protein 1
|
WO2019055460A1
(en)
|
2017-09-13 |
2019-03-21 |
The Children's Medical Center Corporation |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF TRANSPOSON-ASSOCIATED DISEASES
|
US11364303B2
(en)
|
2017-09-29 |
2022-06-21 |
Pfizer Inc. |
Cysteine engineered antibody drug conjugates
|
US11912754B2
(en)
|
2017-10-12 |
2024-02-27 |
Immunowake Inc. |
VEGFR-antibody light chain fusion protein
|
CA3078911A1
(en)
|
2017-10-14 |
2019-04-18 |
Cytomx Therapeutics, Inc. |
Antibodies, activatable antibodies, bispecific antibodies, and bispecific activatable antibodies and methods of use thereof
|
CA3079141A1
(en)
|
2017-10-17 |
2019-04-25 |
Rhizen Pharmaceuticals Sa |
Crac channel modulators for treating esophageal cancer
|
JP7394753B2
(ja)
|
2017-10-18 |
2023-12-08 |
サレプタ セラピューティクス, インコーポレイテッド |
アンチセンスオリゴマー化合物
|
WO2019082124A1
(en)
|
2017-10-26 |
2019-05-02 |
Rhizen Pharmaceuticals Sa |
COMPOSITION AND METHOD FOR THE TREATMENT OF LARGE B-CELL DIFFUSED LYMPHOMA
|
MX2020004381A
(es)
|
2017-10-27 |
2020-08-20 |
Pfizer |
Anticuerpos y conjugados de anticuerpo-farmaco especificos para cd123 y usos de los mismos.
|
KR20200079256A
(ko)
|
2017-10-30 |
2020-07-02 |
리젠 파마슈티컬스 소시에떼 아노님 |
혈액암 및 고형암을 치료하기 위한 칼슘 방출-활성화된 칼슘 채널 조절제
|
WO2019086626A1
(en)
|
2017-11-03 |
2019-05-09 |
Centro Nacional De Investigaciones Cardiovasculares Carlos Iii (F.S.P.) |
MIRNAs AND COMBINATIONS THEREOF FOR USE IN THE TREATMENT OF HUMAN B CELL NEOPLASIAS
|
EA202091082A1
(ru)
|
2017-12-06 |
2020-10-23 |
Ризен Фармасьютикалз Са |
Композиция и способ лечения периферической т-клеточной лимфомы и кожной т-клеточной лимфомы
|
US11946094B2
(en)
|
2017-12-10 |
2024-04-02 |
Augusta University Research Institute, Inc. |
Combination therapies and methods of use thereof
|
JP7344206B2
(ja)
|
2017-12-11 |
2023-09-13 |
アムジェン インコーポレイテッド |
二重特異性抗体製品のための連続製造プロセス
|
UY38041A
(es)
|
2017-12-29 |
2019-06-28 |
Amgen Inc |
Construcción de anticuerpo biespecífico dirigida a muc17 y cd3
|
US20190254973A1
(en)
|
2018-02-22 |
2019-08-22 |
Verily Life Sciences Llc |
Combining orthogonal chemistries for preparation of multiplexed nanoparticles
|
JP2021516045A
(ja)
|
2018-02-28 |
2021-07-01 |
ファイザー・インク |
Il−15バリアントおよびその使用
|
WO2019173771A1
(en)
|
2018-03-09 |
2019-09-12 |
Cytomx Therapeutics, Inc. |
Activatable cd147 antibodies and methods of making and use thereof
|
CN112334484A
(zh)
|
2018-03-14 |
2021-02-05 |
诺维莫尼公司 |
抗-CD3ε抗体及其应用方法
|
WO2019174617A1
(en)
|
2018-03-14 |
2019-09-19 |
Beijing Xuanyi Pharmasciences Co., Ltd. |
Anti-claudin 18.2 antibodies
|
WO2019183320A1
(en)
|
2018-03-21 |
2019-09-26 |
Colorado State University Research Foundation |
Cancer vaccine compositions and methods of use thereof
|
US10722528B2
(en)
|
2018-03-28 |
2020-07-28 |
Augusta University Research Institute, Inc. |
Compositions and methods for inhibiting metastasis
|
WO2019195561A2
(en)
|
2018-04-06 |
2019-10-10 |
BioLegend, Inc. |
Anti-tetraspanin 33 agents and compositions and methods for making and using the same
|
CN116536272A
(zh)
|
2018-04-06 |
2023-08-04 |
儿童医疗中心有限公司 |
用于体细胞重新编程和调整印记的组合物和方法
|
EP3774925A1
(en)
|
2018-04-13 |
2021-02-17 |
Institut national de la santé et de la recherche médicale (INSERM) |
Fc-engineered anti-human ige antibodies and methods of use
|
US20210171610A1
(en)
|
2018-05-02 |
2021-06-10 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis, prevention, and treatment of epstein barr virus infection
|
TWI803637B
(zh)
|
2018-05-23 |
2023-06-01 |
美商輝瑞大藥廠 |
特異性針對gucy2c之抗體及其用途
|
AU2019274654B2
(en)
|
2018-05-23 |
2023-07-20 |
Pfizer Inc. |
Antibodies specific for CD3 and uses thereof
|
WO2019234680A1
(en)
|
2018-06-08 |
2019-12-12 |
Pfizer Inc. |
Methods of treating iron metabolic disease with a neutralizing antibody binding erhythroferrone
|
TWI707683B
(zh)
|
2018-06-13 |
2020-10-21 |
美商輝瑞股份有限公司 |
Glp-1受體促效劑及其用途
|
PT3806855T
(pt)
|
2018-06-15 |
2023-05-03 |
Pfizer |
Agonistas dos receptores de glp-1 e suas utilizações
|
WO2019245817A1
(en)
|
2018-06-19 |
2019-12-26 |
Armo Biosciences, Inc. |
Compositions and methods of use of il-10 agents in conjunction with chimeric antigen receptor cell therapy
|
KR20210027389A
(ko)
|
2018-06-28 |
2021-03-10 |
크리스퍼 테라퓨틱스 아게 |
공여자 폴리뉴클레오티드의 삽입에 의한 게놈 편집을 위한 조성물 및 방법
|
KR20210027436A
(ko)
|
2018-06-29 |
2021-03-10 |
베링거 인겔하임 인터내셔날 게엠베하 |
자가면역 질환을 치료하는데 사용하기 위한 항-cd40 항체
|
BR112020025701A2
(pt)
|
2018-07-06 |
2021-03-16 |
Pfizer Inc. |
Processo de produção e intermediários para um composto de pirrolo[2,3-d]pirimidina e seu uso
|
US20210340238A1
(en)
|
2018-07-11 |
2021-11-04 |
Scholar Rock, Inc. |
TGFß1 INHIBITORS AND USE THEREOF
|
JP2021531254A
(ja)
|
2018-07-11 |
2021-11-18 |
スカラー ロック インコーポレイテッドScholar Rock, Inc. |
高親和性のアイソフォーム選択的TGFβ1阻害剤、およびその使用
|
ES2905160T3
(es)
|
2018-07-11 |
2022-04-07 |
Scholar Rock Inc |
Inhibidores selectivos de la isoforma TGFBeta1 y utilización de los mismos
|
CN112740043A
(zh)
|
2018-07-20 |
2021-04-30 |
皮埃尔法布雷医药公司 |
Vista受体
|
WO2020037125A1
(en)
|
2018-08-16 |
2020-02-20 |
Alnylam Pharmaceuticals Inc. |
Compositions and methods for inhibiting expression of the lect2 gene
|
WO2020055929A1
(en)
*
|
2018-09-11 |
2020-03-19 |
Memorial Sloan Kettering Cancer Center |
Bone marrow-, reticuloendothelial system-, and/or lymph node-targeted radiolabeled liposomes and methods of their diagnostic and therapeutic use
|
CN113365697A
(zh)
|
2018-09-25 |
2021-09-07 |
百进生物科技公司 |
抗tlr9药剂和组合物及其制备方法和使用方法
|
EP3856206A1
(en)
|
2018-09-27 |
2021-08-04 |
Phosphogam, Inc. |
Methods and compositions for the expansion and use of allogeneic gamma/delta-t cells
|
WO2020065409A2
(en)
|
2018-09-28 |
2020-04-02 |
Lyvgen Biopharma Co., Ltd. |
Anti-cd40 binding molecules having engineered fc domains and therapeutic uses thereof
|
CN113166695A
(zh)
|
2018-10-10 |
2021-07-23 |
勃林格殷格翰国际公司 |
用于高密度生物反应器培养中的膜气体转移的方法
|
MX2021003976A
(es)
|
2018-10-11 |
2021-05-27 |
Amgen Inc |
Procesamiento posterior de constructos de anticuerpos biespecificos.
|
US11427591B2
(en)
|
2018-10-17 |
2022-08-30 |
Insilico Medicine Ip Limited |
Kinase inhibitors
|
SG11202104010PA
(en)
|
2018-10-23 |
2021-05-28 |
Scholar Rock Inc |
Rgmc-selective inhibitors and use thereof
|
CN113260383A
(zh)
|
2018-11-02 |
2021-08-13 |
西托姆克斯治疗公司 |
可活化的抗cd166抗体及其使用方法
|
CU20210042A7
(es)
|
2018-11-22 |
2022-01-13 |
Qilu Regor Therapeutics Inc |
Compuestos agonistas de glp-1r y composiciones farmacéuticas que lo contienen
|
CN113454216A
(zh)
|
2018-11-29 |
2021-09-28 |
旗舰先锋创新V股份有限公司 |
调节rna的方法
|
WO2020118109A2
(en)
|
2018-12-06 |
2020-06-11 |
Cytomx Therapeutics, Inc. |
Matrix metalloprotease-cleavable and serine or cysteine protease-cleavable substrates and methods of use thereof
|
MX2021006968A
(es)
|
2018-12-12 |
2021-10-13 |
Kite Pharma Inc |
Antígeno quimérico y receptores de las células t, y métodos de uso.
|
JP2022523051A
(ja)
|
2019-01-22 |
2022-04-21 |
マサチューセッツ インスティテュート オブ テクノロジー |
In Vitroのヒト血液脳関門
|
JP2020117502A
(ja)
|
2019-01-28 |
2020-08-06 |
ファイザー・インク |
変形性関節症の徴候および症状を処置する方法
|
MX2021009175A
(es)
|
2019-01-30 |
2021-09-14 |
Scholar Rock Inc |
Inhibidores especificos del complejo de ltbp de tgf? y usos de los mismos.
|
TWI820301B
(zh)
|
2019-02-15 |
2023-11-01 |
美商輝瑞股份有限公司 |
結晶型嘧啶基-3,8-二氮雜雙環〔3.2.1〕辛烷基甲酮化合物及其用途
|
US20220135663A1
(en)
|
2019-02-18 |
2022-05-05 |
Pfizer Inc. |
Method of treatment of Chronic Low Back Pain
|
CN113874394B
(zh)
|
2019-02-20 |
2024-01-19 |
和铂抗体有限公司 |
抗体
|
US11739078B2
(en)
|
2019-02-22 |
2023-08-29 |
Insilico Medicine Ip Limited |
Methods of inhibiting kinases
|
EP3930761A1
(en)
|
2019-02-26 |
2022-01-05 |
CytomX Therapeutics, Inc. |
Combined therapies of activatable immune checkpoint inhibitors and conjugated activatable antibodies
|
US20200283796A1
(en)
|
2019-03-05 |
2020-09-10 |
Massachusetts Institute Of Technology |
Dna launched rna replicon system (drep) and uses thereof
|
US11717548B2
(en)
|
2019-03-08 |
2023-08-08 |
Massachusetts Institute Of Technology |
Synthetic oncolytic LNP-replicon RNA and uses for cancer immunotherapy
|
KR20220004979A
(ko)
|
2019-03-27 |
2022-01-12 |
유엠씨 우트레크트 홀딩 비.브이. |
조작된 iga 항체 및 사용 방법
|
TW202102266A
(zh)
|
2019-04-01 |
2021-01-16 |
美商建南德克公司 |
用於穩定含有蛋白質之配方之組合物及方法
|
JP7284830B2
(ja)
|
2019-04-02 |
2023-05-31 |
アレイ バイオファーマ インコーポレイテッド |
タンパク質チロシンホスファターゼ阻害剤
|
US20220363673A1
(en)
|
2019-06-28 |
2022-11-17 |
Pfizer Inc. |
5-(Thiophen-2-YL)-1 H-Tetrazole Derivative as BCKDK Inhibitors Useful for Treating Various Diseases
|
TW202115086A
(zh)
|
2019-06-28 |
2021-04-16 |
美商輝瑞大藥廠 |
Bckdk抑制劑
|
LT6699B
(lt)
|
2019-07-15 |
2020-02-10 |
UAB "Valentis" |
Proliposomų gamybos būdas, naudojant ne daugiau kaip 5 % etanolio, ir jų panaudojimas lipofilinių medžiagų kapsuliavimui
|
CN112300279A
(zh)
|
2019-07-26 |
2021-02-02 |
上海复宏汉霖生物技术股份有限公司 |
针对抗cd73抗体和变体的方法和组合物
|
US10758329B1
(en)
|
2019-08-20 |
2020-09-01 |
Raymond L. Wright, III |
Hydrating mouth guard
|
JP2022546570A
(ja)
|
2019-09-03 |
2022-11-04 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
Lect2遺伝子の発現を阻害するための組成物および方法
|
EP4034171A1
(en)
|
2019-09-23 |
2022-08-03 |
Cytomx Therapeutics Inc. |
Anti-cd47 antibodies, activatable anti-cd47 antibodies, and methods of use thereof
|
EP4041767A1
(en)
|
2019-09-26 |
2022-08-17 |
StCube & Co. |
Antibodies specific to glycosylated ctla-4 and methods of use thereof
|
WO2021062096A1
(en)
|
2019-09-26 |
2021-04-01 |
Massachusetts Institute Of Technology |
Microrna-based logic gates and uses thereof
|
WO2021062092A1
(en)
|
2019-09-26 |
2021-04-01 |
Massachusetts Institute Of Technology |
Trans-activated functional rna by strand displacement and uses thereof
|
WO2021067526A1
(en)
|
2019-10-02 |
2021-04-08 |
Alexion Pharmaceuticals, Inc. |
Complement inhibitors for treating drug-induced complement-mediated response
|
WO2021067747A1
(en)
|
2019-10-04 |
2021-04-08 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing ugt1a1 gene expression
|
TWI771766B
(zh)
|
2019-10-04 |
2022-07-21 |
美商輝瑞股份有限公司 |
二醯基甘油醯基轉移酶2 抑制劑
|
CA3153932A1
(en)
|
2019-10-07 |
2021-04-15 |
Jonathan Kipnis |
Modulating lymphatic vessels in neurological disease
|
KR20220088438A
(ko)
|
2019-10-09 |
2022-06-27 |
주식회사 에스티큐브앤컴퍼니 |
글리코실화된 lag3에 대해 특이적인 항체 및 이의 사용 방법
|
CN114786731A
(zh)
|
2019-10-10 |
2022-07-22 |
科达制药股份有限公司 |
治疗眼部病症的方法
|
EP4041773A1
(en)
|
2019-10-11 |
2022-08-17 |
Beth Israel Deaconess Medical Center, Inc. |
Anti-tn antibodies and uses thereof
|
CN114828842A
(zh)
|
2019-10-21 |
2022-07-29 |
理森制药股份公司 |
用于治疗急性髓系白血病的包含dhodh抑制剂的组合物
|
WO2021087325A1
(en)
|
2019-11-01 |
2021-05-06 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing dnajb1-prkaca fusion gene expression
|
EP4073028A1
(en)
|
2019-12-10 |
2022-10-19 |
Pfizer Inc. |
Solid forms of 2-((4-((s)-2-(5-chloropyridin-2-yl)-2-methylbenzo[d] [1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-(((s)-oxetan-2-yl)methyl)-1h-benzo[d] imidazole-6-carboxylic acid, 1,3-dihydroxy-2-(hydroxymethyl)propan-2-amine salt
|
AU2021205440A1
(en)
|
2020-01-11 |
2022-09-01 |
Scholar Rock,Inc. |
TGF-beta inhibitors and use thereof
|
MX2022008609A
(es)
|
2020-01-11 |
2022-11-10 |
Scholar Rock Inc |
Inhibidores de tgf¿ y uso de los mismos.
|
IL294388A
(en)
|
2020-01-14 |
2022-08-01 |
Synthekine Inc |
il2 orthologs and methods of use
|
CN115427447A
(zh)
|
2020-01-17 |
2022-12-02 |
百进生物科技公司 |
抗tlr7药剂和组合物以及制备和使用其的方法
|
EP4093426A1
(en)
|
2020-01-24 |
2022-11-30 |
University of Virginia Patent Foundation |
Modulating lymphatic vessels in neurological disease
|
TW202140786A
(zh)
|
2020-02-10 |
2021-11-01 |
美商艾爾妮蘭製藥公司 |
用於靜默vegf-a表現之組合物及方法
|
JP2022058085A
(ja)
|
2020-02-24 |
2022-04-11 |
ファイザー・インク |
ジアシルグリセロールアシルトランスフェラーゼ2阻害剤とアセチル-CoAカルボキシラーゼ阻害剤との組合せ
|
EP4114456A1
(en)
|
2020-03-06 |
2023-01-11 |
The Colorado State University Research Foundation |
Production of vaccines comprising inactivated sars-cov-2 viral particles
|
JP2023517044A
(ja)
|
2020-03-09 |
2023-04-21 |
ファイザー・インク |
融合タンパク質およびその使用
|
GB202003632D0
(en)
|
2020-03-12 |
2020-04-29 |
Harbour Antibodies Bv |
SARS-Cov-2 (SARS2, COVID-19) antibodies
|
US20230095383A1
(en)
|
2020-03-17 |
2023-03-30 |
Dst Pharma, Inc. |
Methods and compositions for treating viral infections
|
AU2021244695A1
(en)
|
2020-03-26 |
2022-11-10 |
Plx Opco Inc. |
Pharmaceutical carriers capable of pH dependent reconstitution and methods for making and using same
|
CN115348863A
(zh)
|
2020-03-27 |
2022-11-15 |
辉瑞公司 |
以2-[(4-{6-[(4-氰基-2-氟苄基)氧基]吡啶-2-基}哌啶-1-基)甲基]-1-[(2s)-氧杂环丁烷-2-基甲基]-1h-苯并咪唑-6-甲酸或其药学上的盐治疗2型糖尿病或肥胖症或体重过重
|
US20230190785A1
(en)
|
2020-03-30 |
2023-06-22 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing dnajc15 gene expression
|
US20230295622A1
(en)
|
2020-04-06 |
2023-09-21 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing myoc expression
|
EP4133079A1
(en)
|
2020-04-07 |
2023-02-15 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for silencing scn9a expression
|
AU2021252213A1
(en)
|
2020-04-08 |
2022-11-03 |
Pfizer Inc. |
Crystalline forms of 3-cyano-1-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo(1,5-a)pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutaneacetonitrile, and use thereof
|
EP4138911A1
(en)
|
2020-04-24 |
2023-03-01 |
Millennium Pharmaceuticals, Inc. |
Anti-cd19 antibodies and uses thereof
|
EP4146688A1
(en)
|
2020-05-06 |
2023-03-15 |
CRISPR Therapeutics AG |
Mask peptides and masked anti-ptk7 antibodies comprising such
|
WO2021229502A1
(en)
|
2020-05-15 |
2021-11-18 |
Crispr Therapeutics Ag |
Messenger rna encoding cas9 for use in genome-editing systems
|
US20230183707A1
(en)
|
2020-05-21 |
2023-06-15 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting marc1 gene expression
|
EP4157832B1
(en)
|
2020-05-27 |
2024-06-19 |
Qilu Regor Therapeutics Inc. |
Salt and crystal forms of glp-1r agonists and uses thereof
|
CN116113635A
(zh)
|
2020-06-09 |
2023-05-12 |
辉瑞公司 |
作为黑皮质素4受体拮抗剂的螺环化合物及其用途
|
WO2021260577A2
(en)
|
2020-06-26 |
2021-12-30 |
Pfizer Inc. |
Methods of treating inflammatory bowel disease with tl1a antibodies
|
WO2022006562A1
(en)
|
2020-07-03 |
2022-01-06 |
Dana-Farber Cancer Institute, Inc. |
Multispecific coronavirus antibodies
|
TW202216779A
(zh)
|
2020-07-17 |
2022-05-01 |
美商輝瑞股份有限公司 |
治療性抗體類和彼等之用途
|
US20230295257A1
(en)
|
2020-07-24 |
2023-09-21 |
Strand Therapeutics Inc. |
Lipid nanoparticle comprising modified nucleotides
|
IL300113A
(en)
|
2020-07-28 |
2023-03-01 |
Jazz Pharmaceuticals Ireland Ltd |
Compressed cyclic RAF inhibitors and methods of using them
|
MX2023001274A
(es)
|
2020-07-28 |
2023-04-24 |
Jazz Pharmaceuticals Ireland Ltd |
Sintesis quiral de inhibidores de raf biciclicos fusionados.
|
WO2022031869A2
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Gp130 binding molecules and methods of use
|
EP4192852A2
(en)
|
2020-08-05 |
2023-06-14 |
Synthekine, Inc. |
Il10ra binding molecules and methods of use
|
US20230272094A1
(en)
|
2020-08-05 |
2023-08-31 |
Synthekine, Inc. |
Il2rb/il2rg synthetic cytokines
|
WO2022032006A2
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il2rb binding molecules and methods of use
|
TW202214622A
(zh)
|
2020-08-06 |
2022-04-16 |
大陸商上海齊魯銳格醫藥研發有限公司 |
Glp-1r促效劑及其用途
|
IL299911A
(en)
|
2020-08-14 |
2023-03-01 |
Kite Pharma Inc |
Improving immune cell function
|
JP2023541455A
(ja)
|
2020-09-14 |
2023-10-02 |
ブイオーアール バイオファーマ インコーポレーテッド |
Cd33に対する単一ドメイン抗体
|
US20220089759A1
(en)
|
2020-09-21 |
2022-03-24 |
Boehringer Ingelheim International Gmbh |
Use of anti-cd40 antibodies for treatment of inflammatory conditions
|
KR20230104152A
(ko)
|
2020-10-06 |
2023-07-07 |
젠코어 인코포레이티드 |
전신 홍반성 루푸스(sle)를 포함하는 자가면역 질환을 치료하기 위한 바이오마커, 방법 및 조성물
|
CN116710446A
(zh)
|
2020-10-14 |
2023-09-05 |
上海齐鲁锐格医药研发有限公司 |
Glp-1r激动剂的晶型及其用途
|
WO2022093640A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2c agents and compositions and methods for making and using the same
|
WO2022093641A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2a agents and compositions and methods for making and using the same
|
US11058637B1
(en)
*
|
2020-11-25 |
2021-07-13 |
King Abdulaziz University |
Surface-modified emulsomes for intranasal delivery of drugs
|
KR20230124927A
(ko)
|
2020-11-25 |
2023-08-28 |
아카제라 메디신즈, 인크. |
핵산 전달을 위한 지질 나노입자, 및 관련 사용 방법
|
TW202241946A
(zh)
|
2020-12-18 |
2022-11-01 |
美商健生生物科技公司 |
針對整合素α11β1之抗體
|
US20240166707A1
(en)
|
2021-01-08 |
2024-05-23 |
Strand Therapeutics Inc. |
Expression constructs and uses thereof
|
US11033495B1
(en)
|
2021-01-22 |
2021-06-15 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
US11357727B1
(en)
|
2021-01-22 |
2022-06-14 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
US11278494B1
(en)
|
2021-01-22 |
2022-03-22 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
EP4288457A2
(en)
|
2021-02-05 |
2023-12-13 |
Boehringer Ingelheim International GmbH |
Anti-il1rap antibodies
|
WO2022179528A1
(en)
|
2021-02-24 |
2022-09-01 |
Insilico Medicine Ip Limited |
Analogs for the treatment of disease
|
AU2022234333A1
(en)
|
2021-03-11 |
2023-09-28 |
Kite Pharma, Inc. |
Improving immune cell function
|
WO2022195504A1
(en)
|
2021-03-19 |
2022-09-22 |
Pfizer Inc. |
Method of treating osteoarthritis pain with an anti ngf antibody
|
US11952461B2
(en)
|
2021-03-22 |
2024-04-09 |
Sunbio, Inc. |
Siloxy polyethylene glycol and derivatives thereof
|
EP4313309A1
(en)
|
2021-03-22 |
2024-02-07 |
Novimmune S.A. |
Bispecific antibodies targeting cd47 and pd-l1 and methods of use thereof
|
US20220315655A1
(en)
|
2021-03-22 |
2022-10-06 |
Novimmune Sa |
Bispecific antibodies targeting cd47 and pd-l1 and methods of use thereof
|
WO2022204581A2
(en)
|
2021-03-26 |
2022-09-29 |
Scholar Rock, Inc. |
Tgf-beta inhibitors and use thereof
|
EP4320149A1
(en)
|
2021-04-09 |
2024-02-14 |
Takeda Pharmaceutical Company Limited |
Antibodies targeting complement factor d and uses therof
|
CA3214540A1
(en)
|
2021-04-22 |
2022-10-27 |
Pasi A. Janne |
Compositions and methods for treating cancer
|
AR125451A1
(es)
|
2021-04-26 |
2023-07-19 |
Millennium Pharm Inc |
Anticuerpos anti-clec12a y usos de los mismos
|
AR125450A1
(es)
|
2021-04-26 |
2023-07-19 |
Millennium Pharm Inc |
Anticuerpos anti-adgre2 y usos de los mismos
|
EP4334354A1
(en)
|
2021-05-06 |
2024-03-13 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against alk and methods of use thereof
|
WO2022245877A1
(en)
|
2021-05-17 |
2022-11-24 |
Curia Ip Holdings, Llc |
Sars-cov-2 spike protein antibodies
|
WO2022245859A1
(en)
|
2021-05-17 |
2022-11-24 |
Curia Ip Holdings, Llc |
Sars-cov-2 spike protein antibodies
|
WO2022256723A2
(en)
|
2021-06-03 |
2022-12-08 |
Scholar Rock, Inc. |
Tgf-beta inhibitors and therapeutic use thereof
|
AU2022299185A1
(en)
|
2021-06-23 |
2024-01-25 |
Scholar Rock, Inc. |
A myostatin pathway inhibitor in combination with a glp-1 pathway activator for use in treating metabolic disorders
|
WO2023283403A2
(en)
|
2021-07-09 |
2023-01-12 |
Alnylam Pharmaceuticals, Inc. |
Bis-rnai compounds for cns delivery
|
US20230048743A1
(en)
|
2021-07-12 |
2023-02-16 |
Genentech Inc. |
Structures for Reducing Antibody-Lipase Binding
|
WO2023288277A1
(en)
|
2021-07-14 |
2023-01-19 |
Scholar Rock, Inc. |
Ltbp complex-specific inhibitors of tgfb1 and uses thereof
|
WO2023007374A1
(en)
|
2021-07-27 |
2023-02-02 |
Pfizer Inc. |
Method of treatment of cancer pain with tanezumab
|
GB202111757D0
(en)
|
2021-08-17 |
2021-09-29 |
Cantab Biopharmaceuticals Patents Ltd |
Modified colloidal particles for use in the treatment of haemophilia A
|
GB202111758D0
(en)
|
2021-08-17 |
2021-09-29 |
Cantab Biopharmaceuticals Patents Ltd |
Modified colloidal particles for use in the treatment of haemophilia A
|
GB202111759D0
(en)
|
2021-08-17 |
2021-09-29 |
Cantab Biopharmaceuticals Patents Ltd |
Modified colloidal particles
|
CA3230347A1
(en)
|
2021-08-31 |
2023-03-09 |
Pfizer Inc. |
Solid forms of 2-[(4-{6-[(4-cyano-2-fluorobenzyl)oxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(2s)-oxetan-2-ylmethyl]-1h-benzimidazole-6-carboxylic acid, 1,3-dihydroxy-2-(hydroxymethyl)propan-2-amine salt
|
WO2023034901A1
(en)
|
2021-09-01 |
2023-03-09 |
The Broad Institute, Inc. |
Tumor avatar vaccine compositions and uses thereof
|
GB202112935D0
(en)
|
2021-09-10 |
2021-10-27 |
Harbour Antibodies Bv |
Sars-cov-2 (sars2, covid-19) heavy chain only antibodies
|
WO2023036982A1
(en)
|
2021-09-10 |
2023-03-16 |
Harbour Antibodies Bv |
Anti-sars2-s antibodies
|
CA3236038A1
(en)
|
2021-10-20 |
2023-04-27 |
Takeda Pharmaceutical Company Limited |
Compositions targeting bcma and methods of use thereof
|
AU2022375820A1
(en)
|
2021-11-01 |
2024-06-13 |
Tome Biosciences, Inc. |
Single construct platform for simultaneous delivery of gene editing machinery and nucleic acid cargo
|
AU2022383057A1
(en)
|
2021-11-05 |
2024-05-16 |
Abviro Llc |
Human broadly crossreactive influenza monoclonal antibodies and methods of use thereof
|
WO2023097024A1
(en)
|
2021-11-24 |
2023-06-01 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against ctla-4 and methods of use thereof
|
WO2023100061A1
(en)
|
2021-12-01 |
2023-06-08 |
Pfizer Inc. |
3-phenyl-1-benzothiophene-2-carboxylic acid derivatives as branched-chain alpha keto acid dehydrogenase kinase inhibitors for the treatment of diabetes, kidney diseases, nash and heart failure
|
WO2023105387A1
(en)
|
2021-12-06 |
2023-06-15 |
Pfizer Inc. |
Melanocortin 4 receptor antagonists and uses thereof
|
AU2022403854A1
(en)
|
2021-12-08 |
2024-05-23 |
Array Biopharma Inc. |
Crystalline form of n-(2-chloro-3-((5-chloro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino)-4-fluorophenyl)-3-fluoroazetidine-1-sulfonamide
|
WO2023114544A1
(en)
|
2021-12-17 |
2023-06-22 |
Dana-Farber Cancer Institute, Inc. |
Antibodies and uses thereof
|
WO2023111817A1
(en)
|
2021-12-17 |
2023-06-22 |
Pfizer Inc. |
Crystalline forms of [(1r,5s,6r)-3-{2-[(2s)-2-methylazetidin-1-yl]-6-(trifluoromethyl) pyrimidin-4-yl}-3-azabicyclo[3.1.0]hex-6-yl]acetic acid
|
WO2023114543A2
(en)
|
2021-12-17 |
2023-06-22 |
Dana-Farber Cancer Institute, Inc. |
Platform for antibody discovery
|
WO2023122764A1
(en)
|
2021-12-22 |
2023-06-29 |
Tome Biosciences, Inc. |
Co-delivery of a gene editor construct and a donor template
|
WO2023178357A1
(en)
|
2022-03-18 |
2023-09-21 |
Evolveimmune Therapeutics, Inc. |
Bispecific antibody fusion molecules and methods of use thereof
|
WO2023201238A1
(en)
|
2022-04-11 |
2023-10-19 |
Vor Biopharma Inc. |
Binding agents and methods of use thereof
|
WO2023205744A1
(en)
|
2022-04-20 |
2023-10-26 |
Tome Biosciences, Inc. |
Programmable gene insertion compositions
|
WO2023212618A1
(en)
|
2022-04-26 |
2023-11-02 |
Strand Therapeutics Inc. |
Lipid nanoparticles comprising venezuelan equine encephalitis (vee) replicon and uses thereof
|
WO2023215831A1
(en)
|
2022-05-04 |
2023-11-09 |
Tome Biosciences, Inc. |
Guide rna compositions for programmable gene insertion
|
WO2023220641A2
(en)
|
2022-05-11 |
2023-11-16 |
Juno Therapeutics, Inc. |
Methods and uses related to t cell therapy and production of same
|
WO2023225670A2
(en)
|
2022-05-20 |
2023-11-23 |
Tome Biosciences, Inc. |
Ex vivo programmable gene insertion
|
WO2023228023A1
(en)
|
2022-05-23 |
2023-11-30 |
Pfizer Inc. |
Treatment of type 2 diabetes or weight management control with 2-((4-((s)-2-(5-chloropyridin-2-yl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-(((s)-oxetan-2-yl)methyl)-1h-benzo[d]imidazole-6-carboxylic acid or a pharmaceutically salt thereof
|
WO2023235852A1
(en)
|
2022-06-03 |
2023-12-07 |
Zenas Biopharma, Inc. |
Methods and compositions for treating igg4- related diseases
|
WO2024020051A1
(en)
|
2022-07-19 |
2024-01-25 |
BioLegend, Inc. |
Anti-cd157 antibodies, antigen-binding fragments thereof and compositions and methods for making and using the same
|
WO2024030829A1
(en)
|
2022-08-01 |
2024-02-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind to the underside of influenza viral neuraminidase
|
WO2024030850A1
(en)
|
2022-08-01 |
2024-02-08 |
Cytomx Therapeutics, Inc. |
Protease-cleavable substrates and methods of use thereof
|
WO2024030847A1
(en)
|
2022-08-01 |
2024-02-08 |
Cytomx Therapeutics, Inc. |
Protease-cleavable moieties and methods of use thereof
|
WO2024030845A1
(en)
|
2022-08-01 |
2024-02-08 |
Cytomx Therapeutics, Inc. |
Protease-cleavable moieties and methods of use thereof
|
WO2024030843A1
(en)
|
2022-08-01 |
2024-02-08 |
Cytomx Therapeutics, Inc. |
Protease-cleavable moieties and methods of use thereof
|
WO2024030858A1
(en)
|
2022-08-01 |
2024-02-08 |
Cytomx Therapeutics, Inc. |
Protease-cleavable substrates and methods of use thereof
|
WO2024039672A2
(en)
|
2022-08-15 |
2024-02-22 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against msln and methods of use thereof
|
WO2024039670A1
(en)
|
2022-08-15 |
2024-02-22 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against cldn4 and methods of use thereof
|
WO2024040114A2
(en)
|
2022-08-18 |
2024-02-22 |
BioLegend, Inc. |
Anti-axl antibodies, antigen-binding fragments thereof and methods for making and using the same
|
WO2024059165A1
(en)
|
2022-09-15 |
2024-03-21 |
Alnylam Pharmaceuticals, Inc. |
17b-hydroxysteroid dehydrogenase type 13 (hsd17b13) irna compositions and methods of use thereof
|
WO2024075051A1
(en)
|
2022-10-07 |
2024-04-11 |
Pfizer Inc. |
Hsd17b13 inhibitors and/or degraders
|
WO2024084360A1
(en)
|
2022-10-18 |
2024-04-25 |
Pfizer Inc. |
Patatin-like phospholipase domain-containing protein 3 (pnpla3) modifiers
|
WO2024084363A1
(en)
|
2022-10-18 |
2024-04-25 |
Pfizer Inc. |
Use of patatin-like phospholipase domain-containing protein 3 compounds
|
US20240182468A1
(en)
|
2022-10-18 |
2024-06-06 |
Pfizer Inc. |
Compounds for the activation of ampk
|
WO2024084052A1
(en)
|
2022-10-21 |
2024-04-25 |
Novimmune Sa |
Pd-l1xcd28 bispecific antibodies for immune checkpoint-dependent t cell activation
|
GB202216284D0
(en)
|
2022-11-02 |
2022-12-14 |
Ucl Business Ltd |
Self-regulation
|