ATE453381T1 - Nicht-pegylierte lang-zirkulierende liposome - Google Patents

Nicht-pegylierte lang-zirkulierende liposome

Info

Publication number
ATE453381T1
ATE453381T1 AT03258252T AT03258252T ATE453381T1 AT E453381 T1 ATE453381 T1 AT E453381T1 AT 03258252 T AT03258252 T AT 03258252T AT 03258252 T AT03258252 T AT 03258252T AT E453381 T1 ATE453381 T1 AT E453381T1
Authority
AT
Austria
Prior art keywords
liposomes
phospholipid
sucrose
ammonium sulphate
hydration
Prior art date
Application number
AT03258252T
Other languages
English (en)
Inventor
Gautam Vinod Daftary
Srikanth Annappa Pai
Sangeeta Hanurmesh Rivankar
Original Assignee
Bharat Serums & Vaccines Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bharat Serums & Vaccines Ltd filed Critical Bharat Serums & Vaccines Ltd
Application granted granted Critical
Publication of ATE453381T1 publication Critical patent/ATE453381T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03258252T 2002-12-31 2003-12-31 Nicht-pegylierte lang-zirkulierende liposome ATE453381T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1101MU2002 2002-12-31

Publications (1)

Publication Number Publication Date
ATE453381T1 true ATE453381T1 (de) 2010-01-15

Family

ID=32500467

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03258252T ATE453381T1 (de) 2002-12-31 2003-12-31 Nicht-pegylierte lang-zirkulierende liposome

Country Status (19)

Country Link
EP (1) EP1435231B8 (de)
JP (1) JP5355842B2 (de)
KR (2) KR101171045B1 (de)
CN (1) CN1756533B (de)
AT (1) ATE453381T1 (de)
AU (1) AU2003303368B2 (de)
BR (1) BR0317882A (de)
CA (1) CA2511464C (de)
DE (1) DE60330745D1 (de)
DK (1) DK1435231T3 (de)
EA (1) EA008930B1 (de)
ES (1) ES2337563T3 (de)
HK (1) HK1089946A1 (de)
IL (1) IL169364A (de)
MX (1) MXPA05007102A (de)
NZ (1) NZ540778A (de)
PT (1) PT1435231E (de)
WO (1) WO2004058140A2 (de)
ZA (1) ZA200504850B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2687291A1 (en) * 2007-05-16 2008-11-20 Ktb Tumorforschungsgesellschaft Mbh Low-viscous anthracycline formulation
JP5622719B2 (ja) 2009-03-30 2014-11-12 エーザイ・アール・アンド・ディー・マネジメント株式会社 リポソーム組成物の製造方法
PL2415470T3 (pl) 2009-03-30 2016-12-30 Kompozycja liposomowa
JP2014506922A (ja) * 2011-03-01 2014-03-20 ティーオー − ビービービー ホールディング ベスローテン フェンノートシャップ 難水溶性物質の高度なアクティブリポソームローディング
NZ769187A (en) * 2014-11-25 2023-07-28 Curadigm Sas Pharmaceutical composition, preparation and uses thereof
WO2017188350A1 (ja) 2016-04-28 2017-11-02 エーザイ・アール・アンド・ディー・マネジメント株式会社 腫瘍の成長を抑制する方法
KR20190062485A (ko) * 2016-09-27 2019-06-05 버텍스 파마슈티칼스 인코포레이티드 Dna-손상제 및 dna-pk 저해제의 조합을 사용한 암 치료 방법
US11083705B2 (en) 2019-07-26 2021-08-10 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
US12036204B2 (en) 2019-07-26 2024-07-16 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
CN116570775B (zh) * 2023-05-16 2024-08-02 万瑞飞鸿(北京)医疗器材有限公司 一种药物涂层、血管支架及其制备方法和应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
WO1985000968A1 (en) * 1983-09-06 1985-03-14 Health Research, Inc. Liposome delivery method for decreasing the toxicity of an antitumor drug
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
CA1270198A (en) * 1984-08-08 1990-06-12 Marcel B. Bally Encapsulation of antineoplastic agents in liposomes
US4920016A (en) 1986-12-24 1990-04-24 Linear Technology, Inc. Liposomes with enhanced circulation time
CA1338702C (en) * 1987-03-05 1996-11-12 Lawrence D. Mayer High drug:lipid formulations of liposomal- antineoplastic agents
JPH0720857B2 (ja) 1988-08-11 1995-03-08 テルモ株式会社 リポソームおよびその製法
IL91664A (en) * 1988-09-28 1993-05-13 Yissum Res Dev Co Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release
US6132763A (en) 1988-10-20 2000-10-17 Polymasc Pharmaceuticals Plc Liposomes
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
ES2208946T3 (es) * 1996-08-23 2004-06-16 Sequus Pharmaceuticals, Inc. Liposomas que contienen un compuesto de cisplatino.
ATE238039T1 (de) * 1998-09-16 2003-05-15 Alza Corp In liposomen eingeschlossene topoisomerase inhibitoren
KR20000061075A (ko) * 1999-03-23 2000-10-16 린 중친 리포솜의 응집을 방지하기 위한 방법 및 조성물
GB0111279D0 (en) * 2001-05-10 2001-06-27 Nycomed Imaging As Radiolabelled liposomes

Also Published As

Publication number Publication date
EP1435231B8 (de) 2010-03-03
DE60330745D1 (de) 2010-02-11
DK1435231T3 (da) 2010-04-26
ZA200504850B (en) 2006-08-30
WO2004058140B1 (en) 2004-12-16
NZ540778A (en) 2008-04-30
EP1435231B1 (de) 2009-12-30
MXPA05007102A (es) 2005-08-26
AU2003303368A1 (en) 2004-07-22
KR20110075051A (ko) 2011-07-05
CA2511464C (en) 2011-08-23
WO2004058140A3 (en) 2004-10-28
JP2006513189A (ja) 2006-04-20
CN1756533B (zh) 2010-06-16
IL169364A (en) 2012-05-31
EP1435231A1 (de) 2004-07-07
KR101171045B1 (ko) 2012-08-03
EA200500850A1 (ru) 2006-02-24
AU2003303368B2 (en) 2010-06-17
PT1435231E (pt) 2010-04-08
CN1756533A (zh) 2006-04-05
WO2004058140A2 (en) 2004-07-15
KR101133084B1 (ko) 2012-04-04
BR0317882A (pt) 2005-12-13
KR20050088233A (ko) 2005-09-02
EA008930B1 (ru) 2007-08-31
HK1089946A1 (en) 2006-12-15
JP5355842B2 (ja) 2013-11-27
IL169364A0 (en) 2007-07-04
CA2511464A1 (en) 2004-07-15
ES2337563T3 (es) 2010-04-27

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