HK1089946A1 - Non-pegylated long-circulating liposomes - Google Patents
Non-pegylated long-circulating liposomesInfo
- Publication number
- HK1089946A1 HK1089946A1 HK06110458.8A HK06110458A HK1089946A1 HK 1089946 A1 HK1089946 A1 HK 1089946A1 HK 06110458 A HK06110458 A HK 06110458A HK 1089946 A1 HK1089946 A1 HK 1089946A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- liposomes
- phospholipid
- sucrose
- ammonium sulphate
- hydration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1101MU2002 | 2002-12-31 | ||
PCT/IN2003/000424 WO2004058140A2 (en) | 2002-12-31 | 2003-12-31 | Non-pegylated long-circulating liposomes |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1089946A1 true HK1089946A1 (en) | 2006-12-15 |
Family
ID=32500467
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06110458.8A HK1089946A1 (en) | 2002-12-31 | 2006-09-20 | Non-pegylated long-circulating liposomes |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP1435231B8 (de) |
JP (1) | JP5355842B2 (de) |
KR (2) | KR101171045B1 (de) |
CN (1) | CN1756533B (de) |
AT (1) | ATE453381T1 (de) |
AU (1) | AU2003303368B2 (de) |
BR (1) | BR0317882A (de) |
CA (1) | CA2511464C (de) |
DE (1) | DE60330745D1 (de) |
DK (1) | DK1435231T3 (de) |
EA (1) | EA008930B1 (de) |
ES (1) | ES2337563T3 (de) |
HK (1) | HK1089946A1 (de) |
IL (1) | IL169364A (de) |
MX (1) | MXPA05007102A (de) |
NZ (1) | NZ540778A (de) |
PT (1) | PT1435231E (de) |
WO (1) | WO2004058140A2 (de) |
ZA (1) | ZA200504850B (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0811248A2 (pt) | 2007-05-16 | 2014-11-04 | Ktb Tumorforschungs Gmbh | Formulação de antraciclina de baixa viscosidade. |
PT2415470T (pt) * | 2009-03-30 | 2016-08-31 | Eisai R&D Man Co Ltd | Composição de lipossomas |
JP5622719B2 (ja) | 2009-03-30 | 2014-11-12 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | リポソーム組成物の製造方法 |
EP2680820B1 (de) * | 2011-03-01 | 2022-11-02 | 2-BBB Medicines B.V. | Fortschrittliches, aktives liposomales laden von schwer wasserlöslichen substanzen |
JP6789960B2 (ja) * | 2014-11-25 | 2020-11-25 | キュラディグム・エスアエスCuradigm Sas | 医薬組成物、その調製及び使用 |
JP7015237B2 (ja) | 2016-04-28 | 2022-02-02 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 腫瘍の成長を抑制する方法 |
WO2018064092A1 (en) * | 2016-09-27 | 2018-04-05 | Vertex Pharmaceuticals Incorporated | Method for treating cancer using a combination of dna-damaging agents and dna-pk inhibitors |
US11083705B2 (en) | 2019-07-26 | 2021-08-10 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
US12036204B2 (en) | 2019-07-26 | 2024-07-16 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
CN116570775B (zh) * | 2023-05-16 | 2024-08-02 | 万瑞飞鸿(北京)医疗器材有限公司 | 一种药物涂层、血管支架及其制备方法和应用 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
WO1985000968A1 (en) * | 1983-09-06 | 1985-03-14 | Health Research, Inc. | Liposome delivery method for decreasing the toxicity of an antitumor drug |
CA1270198A (en) * | 1984-08-08 | 1990-06-12 | Marcel B. Bally | Encapsulation of antineoplastic agents in liposomes |
US4880635B1 (en) * | 1984-08-08 | 1996-07-02 | Liposome Company | Dehydrated liposomes |
US4920016A (en) | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
CA1338702C (en) * | 1987-03-05 | 1996-11-12 | Lawrence D. Mayer | High drug:lipid formulations of liposomal- antineoplastic agents |
JPH0720857B2 (ja) | 1988-08-11 | 1995-03-08 | テルモ株式会社 | リポソームおよびその製法 |
IL91664A (en) * | 1988-09-28 | 1993-05-13 | Yissum Res Dev Co | Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release |
US6132763A (en) | 1988-10-20 | 2000-10-17 | Polymasc Pharmaceuticals Plc | Liposomes |
US5013556A (en) * | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
CA2263455C (en) * | 1996-08-23 | 2002-10-29 | Sequus Pharmaceuticals, Inc. | Liposomes containing a cisplatin compound |
ATE238039T1 (de) * | 1998-09-16 | 2003-05-15 | Alza Corp | In liposomen eingeschlossene topoisomerase inhibitoren |
KR20000061075A (ko) * | 1999-03-23 | 2000-10-16 | 린 중친 | 리포솜의 응집을 방지하기 위한 방법 및 조성물 |
GB0111279D0 (en) * | 2001-05-10 | 2001-06-27 | Nycomed Imaging As | Radiolabelled liposomes |
-
2003
- 2003-12-31 NZ NZ540778A patent/NZ540778A/en not_active IP Right Cessation
- 2003-12-31 EA EA200500850A patent/EA008930B1/ru not_active IP Right Cessation
- 2003-12-31 CA CA2511464A patent/CA2511464C/en not_active Expired - Fee Related
- 2003-12-31 PT PT03258252T patent/PT1435231E/pt unknown
- 2003-12-31 AU AU2003303368A patent/AU2003303368B2/en not_active Ceased
- 2003-12-31 AT AT03258252T patent/ATE453381T1/de active
- 2003-12-31 MX MXPA05007102A patent/MXPA05007102A/es active IP Right Grant
- 2003-12-31 EP EP03258252A patent/EP1435231B8/de not_active Expired - Lifetime
- 2003-12-31 KR KR1020117014172A patent/KR101171045B1/ko not_active IP Right Cessation
- 2003-12-31 JP JP2004562836A patent/JP5355842B2/ja not_active Expired - Fee Related
- 2003-12-31 KR KR1020057012107A patent/KR101133084B1/ko not_active IP Right Cessation
- 2003-12-31 DE DE60330745T patent/DE60330745D1/de not_active Expired - Lifetime
- 2003-12-31 DK DK03258252.0T patent/DK1435231T3/da active
- 2003-12-31 CN CN2003801100257A patent/CN1756533B/zh not_active Expired - Fee Related
- 2003-12-31 ES ES03258252T patent/ES2337563T3/es not_active Expired - Lifetime
- 2003-12-31 BR BR0317882-0A patent/BR0317882A/pt not_active IP Right Cessation
- 2003-12-31 WO PCT/IN2003/000424 patent/WO2004058140A2/en active Application Filing
-
2005
- 2005-06-14 ZA ZA200504850A patent/ZA200504850B/en unknown
- 2005-06-23 IL IL169364A patent/IL169364A/en not_active IP Right Cessation
-
2006
- 2006-09-20 HK HK06110458.8A patent/HK1089946A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2004058140A3 (en) | 2004-10-28 |
ES2337563T3 (es) | 2010-04-27 |
JP5355842B2 (ja) | 2013-11-27 |
EP1435231A1 (de) | 2004-07-07 |
IL169364A0 (en) | 2007-07-04 |
WO2004058140B1 (en) | 2004-12-16 |
AU2003303368A1 (en) | 2004-07-22 |
ATE453381T1 (de) | 2010-01-15 |
KR101171045B1 (ko) | 2012-08-03 |
EA200500850A1 (ru) | 2006-02-24 |
CN1756533B (zh) | 2010-06-16 |
ZA200504850B (en) | 2006-08-30 |
EA008930B1 (ru) | 2007-08-31 |
AU2003303368B2 (en) | 2010-06-17 |
PT1435231E (pt) | 2010-04-08 |
CA2511464C (en) | 2011-08-23 |
NZ540778A (en) | 2008-04-30 |
KR20050088233A (ko) | 2005-09-02 |
CA2511464A1 (en) | 2004-07-15 |
DK1435231T3 (da) | 2010-04-26 |
CN1756533A (zh) | 2006-04-05 |
DE60330745D1 (de) | 2010-02-11 |
BR0317882A (pt) | 2005-12-13 |
MXPA05007102A (es) | 2005-08-26 |
EP1435231B1 (de) | 2009-12-30 |
KR101133084B1 (ko) | 2012-04-04 |
KR20110075051A (ko) | 2011-07-05 |
IL169364A (en) | 2012-05-31 |
WO2004058140A2 (en) | 2004-07-15 |
JP2006513189A (ja) | 2006-04-20 |
EP1435231B8 (de) | 2010-03-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1089946A1 (en) | Non-pegylated long-circulating liposomes | |
MY143051A (en) | Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes | |
HK1062140A1 (en) | 4-fluoro-n-indan-2-yl benzamide and its use as pharmaceutical 4-n-(1,2-2-?) | |
IL151657A0 (en) | Methods and kits for locally administering an active agent to an interstitial space of a host | |
EA200300457A1 (ru) | Кристаллический моногидрат, способ его получения и его применение для получения лекарственного средства | |
CA2250219A1 (en) | Materials and methods for making improved liposome compositions | |
AR002262A1 (es) | Composicion y metodo para el tratamiento de enfermedades fungales de las unas y un vendaje adaptado para la administracion topica de medicacion a lasunas. | |
WO2004110346A3 (en) | Sustained release of antiinfectives | |
ITMI991884A0 (it) | Composizioni per la cura della pelle e loro impiego nel curare una pel le danneggiata | |
BR0117106A (pt) | Compostos de lipossoma de microesfera de gás | |
WO2007003948A3 (en) | Core 2 glcnac-t inhibitors | |
IT8812585A0 (it) | Preparato, in particolare preparato cosmetico antisolare, nonche' metodo per l'introduzione di una sostanza attiva nella pelle | |
NO180147C (no) | Fremgangsmåte for fremstilling av HDLC eller et liposom innbefattende et polyen-antisopp-antibiotikum og et lipid | |
AU2469101A (en) | Methods for inducing atrial and ventricular rhythms using ultrasound and microbubbles | |
RU2210573C2 (ru) | Углеводные производные | |
LV5765B4 (lv) | (S)-(-)-1-propil-2',6'-pipekoloksilidida hidrohlorida monohidrats ta iegusanas metode un to satuross farmaceitisks preparats | |
WO2003059246A3 (en) | Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections | |
BR9606528A (pt) | Composto sal de um composto processo para a preparação de um composto composição farmacêutica produto uso de um composto e método para o tratmento de um mamífero que necessita de um agente antineoplásico | |
CO4960654A1 (es) | Metodo para el tratamiento de enfermedades fisiologicas relacionadas con el uso o con las secuelas provocadas por el uso de la cocaina u otros estimulantes psicomotores | |
NZ516765A (en) | Topical formulations comprising skin penetration agents and the use thereof | |
CA2241825A1 (en) | New monofunctionalized edta, dtpa and ttha derivatives and their use in medical diagnosis and therapy | |
EP1301203A4 (de) | Impfstoff beinhaltend azyl-glyceryl phosphatidylinositol manno-oligosaccharide als aktive substanz | |
PL335016A1 (en) | Novel polymorph of 3,4-dihydro-4-oxo-3-[(5-trifluoromethyl)-2-benzoylthiazolyl)methyl]-1-phtalazine acetic acid monohydrate, method of obtaining same, method of obtaining anhydrous 3,4-dihydro-4-oxo-3-[(5-trifluoromethyl)-2-benzoylthiazolyl)methyl-1-phtalazine acetic acid, therapeutic methods, pharmaceutic agent, application of said polymorph in production of such pharmaceutic agent and method of obtaining the last mentioned one | |
ES2036661T3 (es) | Un metodo para preparar una preparacion farmaceutica de pie de atleta. | |
WO2003000232A3 (en) | Method for preparation of vesicles loaded with immunostimulator y oligodeoxynucleotides |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20151231 |