MX337052B - Peptidos que se enlazan a fosfatidiletanolamina y sus usos en el tratamiento de infecciones virales y del cancer. - Google Patents
Peptidos que se enlazan a fosfatidiletanolamina y sus usos en el tratamiento de infecciones virales y del cancer.Info
- Publication number
- MX337052B MX337052B MX2011000908A MX2011000908A MX337052B MX 337052 B MX337052 B MX 337052B MX 2011000908 A MX2011000908 A MX 2011000908A MX 2011000908 A MX2011000908 A MX 2011000908A MX 337052 B MX337052 B MX 337052B
- Authority
- MX
- Mexico
- Prior art keywords
- aminophospholipids
- cancer
- viral infections
- anionic phospholipids
- treating viral
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 208000036142 Viral infection Diseases 0.000 title abstract 3
- -1 anionic phospholipids Chemical class 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 230000009385 viral infection Effects 0.000 title abstract 3
- 108010067071 duramycin Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940127121 immunoconjugate Drugs 0.000 abstract 1
- SFWLDKQAUHFCBS-WWXQEMPQSA-N lancovutide Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H]2C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@@H](CCCCNC[C@H]4C(=O)N[C@@H](CC=5C=CC=CC=5)C(=O)NCC(=O)N5CCC[C@H]5C(=O)N[C@@H](CC=5C=CC=CC=5)C(=O)N[C@H]([C@@H](SC[C@H](NC(=O)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSC3C)CSC2)C(=O)N4)C)C(=O)N1)C(O)=O)[C@@H](O)C(O)=O)=O)C(C)C)C1=CC=CC=C1 SFWLDKQAUHFCBS-WWXQEMPQSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000005166 vasculature Anatomy 0.000 abstract 1
- 230000007502 viral entry Effects 0.000 abstract 1
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Abstract
La presente invención se refiere a descubrimientos concernientes al papel que juegan fosfolípidos aniónicos y aminofosfolípidos, en la vasculatura de tumores y en la entrada y diseminación viral, y composiciones y métodos para utilizar estos descubrimientos en el tratamiento del cáncer y de infecciones virales. También se describen composiciones a base de anticuerpos, inmunoconjugados y duramicina, y combinaciones que se enlazan e inhiben los fosfolípidos aniónicos y los aminofosfolípidos, para el uso en el tratamiento seguro y efectivo del cáncer, infecciones virales y enfermedades relacionadas.
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| US39626302P | 2002-07-15 | 2002-07-15 | |
| PCT/US2003/021925 WO2004006847A2 (en) | 2002-07-15 | 2003-07-15 | Selected antibodies and duramycin peptides binding to anionic phospholipids and aminophospholipids and their use in treating viral infections and cancer |
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| MX2011000908A MX337052B (es) | 2002-07-15 | 2003-07-15 | Peptidos que se enlazan a fosfatidiletanolamina y sus usos en el tratamiento de infecciones virales y del cancer. |
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| MXPA05000652A MXPA05000652A (es) | 2002-07-15 | 2003-07-15 | Anticuerpos seleccionados y peptidos de duramicina que se enlazan a fosfolipidos anionicos y aminofosfolipidos y sus usos en el tratamiento de infecciones virales y del cancer. |
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