|
CA2516320C
(en)
|
2003-02-18 |
2015-05-26 |
Kevin Slawin |
Induced activation in dendritic cells
|
|
US20130266551A1
(en)
|
2003-11-05 |
2013-10-10 |
St. Jude Children's Research Hospital, Inc. |
Chimeric receptors with 4-1bb stimulatory signaling domain
|
|
US7435596B2
(en)
|
2004-11-04 |
2008-10-14 |
St. Jude Children's Research Hospital, Inc. |
Modified cell line and method for expansion of NK cell
|
|
WO2008039874A2
(en)
|
2006-09-26 |
2008-04-03 |
Cedars-Sinai Medical Center |
Cancer stem cell antigen vaccines and methods
|
|
WO2008039974A2
(en)
|
2006-09-28 |
2008-04-03 |
Cedars-Sinai Medical Center |
Cancer vaccines and vaccination methods
|
|
US8450112B2
(en)
|
2008-04-09 |
2013-05-28 |
Maxcyte, Inc. |
Engineering and delivery of therapeutic compositions of freshly isolated cells
|
|
PL2328923T3
(pl)
|
2008-09-02 |
2016-06-30 |
Cedars Sinai Medical Center |
Epitopy CD133
|
|
US8415150B2
(en)
*
|
2009-02-24 |
2013-04-09 |
The Trustees Of The University Of Pennsylvania |
Methods for treating progressive multifocal leukoencephalopathy (PML)
|
|
US10426740B1
(en)
|
2010-08-18 |
2019-10-01 |
Avm Biotechnology, Llc |
Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues
|
|
CA2815000C
(en)
|
2010-10-22 |
2024-05-21 |
Dana-Farber Cancer Institute, Inc. |
Discovery of regulatory t cells programmed to suppress an immune response
|
|
PH12013501201A1
(en)
*
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
ES2625288T3
(es)
|
2011-04-15 |
2017-07-19 |
The Johns Hopkins University |
Sistema de secuenciación segura
|
|
WO2013059593A1
(en)
*
|
2011-10-20 |
2013-04-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-cd22 chimeric antigen receptors
|
|
WO2013063419A2
(en)
*
|
2011-10-28 |
2013-05-02 |
The Trustees Of The University Of Pennsylvania |
A fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
|
|
MX2014010185A
(es)
|
2012-02-22 |
2014-11-14 |
Univ Pennsylvania |
Uso de dominio de señalizacion cd2 en receptores de antigeno quimericos de segunda generacion.
|
|
WO2013126712A1
(en)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for generating a persisting population of t cells useful for the treatment of cancer
|
|
PE20190658A1
(es)
|
2012-02-24 |
2019-05-08 |
Abbvie Stemcentrx Llc |
Moduladores y metodos de empleo novedosos
|
|
US9359447B2
(en)
|
2012-03-23 |
2016-06-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mesothelin chimeric antigen receptors
|
|
EA033110B1
(ru)
|
2012-04-11 |
2019-08-30 |
Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез |
Химерный рецептор антигена, направленный на антиген созревания b-клеток, кодирующая его нуклеиновая кислота, соответствующие экспрессионный вектор, клетка-хозяин, применения и способы
|
|
KR102437522B1
(ko)
|
2012-05-25 |
2022-08-26 |
셀렉티스 |
면역요법을 위한 동종이형 및 면역억제제 저항성인 t 세포의 조작 방법
|
|
LT4461308T
(lt)
|
2012-07-13 |
2025-06-10 |
The Trustees Of The University Of Pennsylvania |
Car priešnavikinio aktyvumo toksiškumo valdymas
|
|
KR20150029714A
(ko)
|
2012-07-13 |
2015-03-18 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
이중특이적 항체의 공-도입에 의한 car 세포의 활성 증강
|
|
CN104507537A
(zh)
*
|
2012-07-13 |
2015-04-08 |
宾夕法尼亚大学董事会 |
用于调节car t细胞的组合物和方法
|
|
AU2013289979A1
(en)
*
|
2012-07-13 |
2015-01-22 |
The Trustees Of The University Of Pennsylvania |
Methods of assessing the suitability of transduced T cells for administration
|
|
US20150290244A1
(en)
*
|
2012-07-13 |
2015-10-15 |
The Trustees Of The University Of Pennsylvania |
Use of cart19 to deplete normal b cells to induce tolerance
|
|
US20160235787A1
(en)
*
|
2012-07-13 |
2016-08-18 |
The Trustees Of The University Of Pennsylvania |
Epitope Spreading Associated with CAR T-Cells
|
|
CA2881981A1
(en)
*
|
2012-08-20 |
2014-02-27 |
Fred Hutchinson Cancer Research Center |
Method and compositions for cellular immunotherapy
|
|
CN104769103B
(zh)
*
|
2012-09-04 |
2018-06-08 |
塞勒克提斯公司 |
多链嵌合抗原受体和其用途
|
|
CN104955845B
(zh)
*
|
2012-09-27 |
2018-11-16 |
美国政府(由卫生和人类服务部的部长所代表) |
间皮素抗体和引起有效的抗肿瘤活性的方法
|
|
WO2014052545A2
(en)
|
2012-09-28 |
2014-04-03 |
Dana-Farber Cancer Institute, Inc. |
Targeted expansion of qa-1-peptide-specific regulatory cd8 t cells to ameliorate arthritis
|
|
WO2014055442A2
(en)
*
|
2012-10-01 |
2014-04-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for targeting stromal cells for the treatment of cancer
|
|
US9598489B2
(en)
|
2012-10-05 |
2017-03-21 |
The Trustees Of The Univeristy Of Pennsylvania |
Human alpha-folate receptor chimeric antigen receptor
|
|
WO2014055657A1
(en)
|
2012-10-05 |
2014-04-10 |
The Trustees Of The University Of Pennsylvania |
Use of a trans-signaling approach in chimeric antigen receptors
|
|
CN104822705B
(zh)
|
2012-10-24 |
2019-07-12 |
美国卫生和人力服务部 |
M971嵌合抗原受体
|
|
AU2013338393C1
(en)
|
2012-10-29 |
2024-07-25 |
The Johns Hopkins University |
Papanicolaou test for ovarian and endometrial cancers
|
|
AU2013204922B2
(en)
*
|
2012-12-20 |
2015-05-14 |
Celgene Corporation |
Chimeric antigen receptors
|
|
AU2015210373B2
(en)
*
|
2012-12-20 |
2017-04-06 |
Celgene Corporation |
Chimeric antigen receptors
|
|
EP2934532B1
(en)
|
2012-12-20 |
2019-10-23 |
Purdue Research Foundation |
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
|
|
SG11201507026WA
(en)
*
|
2013-02-06 |
2015-10-29 |
Anthrogenesis Corp |
Modified t lymphocytes having improved specificity
|
|
US10137182B2
(en)
|
2013-02-14 |
2018-11-27 |
Immunocellular Therapeutics, Ltd. |
Cancer vaccines and vaccination methods
|
|
EP4303232A3
(en)
|
2013-02-15 |
2024-04-17 |
The Regents of The University of California |
Chimeric antigen receptor and methods of use thereof
|
|
TW201446794A
(zh)
|
2013-02-20 |
2014-12-16 |
Novartis Ag |
利用抗-cd123嵌合抗原受體工程化t細胞之初級人類白血病有效靶向
|
|
DK2958943T3
(da)
|
2013-02-20 |
2019-12-09 |
Univ Pennsylvania |
Behandling af cancer ved anvendelse af humaniseret anti-EGFRvIII kimær antigenreceptor
|
|
BR112015019909A2
(pt)
|
2013-02-22 |
2017-08-29 |
Abbvie Stemcentrx Llc |
Conjugados anticorpo-fármaco, composição farmacêutica, usos dos mesmos, e kit
|
|
PT2961831T
(pt)
|
2013-02-26 |
2020-10-12 |
Memorial Sloan Kettering Cancer Center |
Composições e métodos para imunoterapêutica
|
|
EP3447072A3
(en)
*
|
2013-03-05 |
2019-05-22 |
Baylor College of Medicine |
Engager cells comprising cd3 scfv and an antigen recognition domain that binds a tumor antigen for immunotherapy
|
|
US9587237B2
(en)
|
2013-03-14 |
2017-03-07 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
|
WO2014153114A1
(en)
*
|
2013-03-14 |
2014-09-25 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to modify cells for therapeutic objectives
|
|
US9499855B2
(en)
*
|
2013-03-14 |
2016-11-22 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
|
WO2014151960A2
(en)
*
|
2013-03-14 |
2014-09-25 |
Bellicum Pharmaceuticals, Inc. |
Methods for controlling t cell proliferation
|
|
US20150064153A1
(en)
|
2013-03-15 |
2015-03-05 |
The Trustees Of Princeton University |
High efficiency microfluidic purification of stem cells to improve transplants
|
|
EP3569313A1
(en)
|
2013-03-15 |
2019-11-20 |
GPB Scientific, LLC |
On-chip microfluidic processing of particles
|
|
AU2014240083C1
(en)
*
|
2013-03-15 |
2019-10-24 |
Celgene Corporation |
Modified T lymphocytes
|
|
US9657105B2
(en)
*
|
2013-03-15 |
2017-05-23 |
City Of Hope |
CD123-specific chimeric antigen receptor redirected T cells and methods of their use
|
|
EP2970426B1
(en)
|
2013-03-15 |
2019-08-28 |
Michael C. Milone |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
US12590955B2
(en)
|
2013-03-15 |
2026-03-31 |
Zeon Corporation |
Methods and systems for processing particles
|
|
WO2015142314A1
(en)
|
2013-03-15 |
2015-09-24 |
Memorial Sloan-Kettering Cancer Center |
Compositions and methods for immunotherapy
|
|
EP3608022A1
(en)
|
2013-03-15 |
2020-02-12 |
The Trustees of Princeton University |
Methods and devices for high throughput purification
|
|
UY35468A
(es)
*
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
WO2014160627A1
(en)
|
2013-03-25 |
2014-10-02 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-cd276 polypeptides, proteins, and chimeric antigen receptors
|
|
CN115028735A
(zh)
*
|
2013-05-03 |
2022-09-09 |
俄亥俄州创新基金会 |
Cs1-特异性嵌合抗原受体工程化的免疫效应细胞
|
|
US10260038B2
(en)
|
2013-05-10 |
2019-04-16 |
Whitehead Institute For Biomedical Research |
Protein modification of living cells using sortase
|
|
PL3546572T3
(pl)
*
|
2013-05-13 |
2024-07-22 |
Cellectis |
Chimeryczny receptor antygenowy swoisty względem cd19 i jego zastosowania
|
|
US11077144B2
(en)
|
2013-05-13 |
2021-08-03 |
Cellectis |
CD19 specific chimeric antigen receptor and uses thereof
|
|
US11311575B2
(en)
*
|
2013-05-13 |
2022-04-26 |
Cellectis |
Methods for engineering highly active T cell for immunotherapy
|
|
EP3783098A1
(en)
|
2013-05-14 |
2021-02-24 |
Board Of Regents, The University Of Texas System |
Human application of engineered chimeric antigen receptor (car) t-cells
|
|
AU2014268364A1
(en)
|
2013-05-24 |
2015-12-10 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptor-targeting monoclonal antibodies
|
|
ES2897579T3
(es)
|
2013-06-10 |
2022-03-01 |
Dana Farber Cancer Inst Inc |
Métodos y composiciones para reducir la inmunosupresión por células tumorales
|
|
US10208125B2
(en)
|
2013-07-15 |
2019-02-19 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Anti-mucin 1 binding agents and uses thereof
|
|
AU2014312215B2
(en)
|
2013-08-28 |
2020-02-27 |
Abbvie Stemcentrx Llc |
Site-specific antibody conjugation methods and compositions
|
|
KR102271498B1
(ko)
|
2013-08-30 |
2021-07-05 |
보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 |
종양 치료를 위한 키누레닌 고갈 효소의 투여
|
|
US10570204B2
(en)
|
2013-09-26 |
2020-02-25 |
The Medical College Of Wisconsin, Inc. |
Methods for treating hematologic cancers
|
|
CN105813654B
(zh)
|
2013-10-11 |
2019-05-31 |
美国政府(由卫生和人类服务部的部长所代表) |
Tem8抗体及其用途
|
|
KR102339240B1
(ko)
|
2013-10-15 |
2021-12-15 |
더 스크립스 리서치 인스티튜트 |
펩타이드 키메라 항원 수용체 t 세포 스위치 및 이의 용도
|
|
EP3057991B8
(en)
*
|
2013-10-15 |
2019-09-04 |
The Scripps Research Institute |
Chimeric antigen receptor t cell switches and uses thereof
|
|
US10144770B2
(en)
*
|
2013-10-17 |
2018-12-04 |
National University Of Singapore |
Chimeric receptors and uses thereof in immune therapy
|
|
EP3057986B1
(en)
*
|
2013-10-17 |
2017-12-27 |
National University of Singapore |
Chimeric receptor that triggers antibody-dependent cell cytotoxicity against multiple tumors
|
|
CN104561069A
(zh)
*
|
2013-10-23 |
2015-04-29 |
深圳先进技术研究院 |
含重组嵌合抗原受体基因表达盒的微环dna重组母质粒、含该表达盒的微环dna及应用
|
|
WO2015069922A2
(en)
|
2013-11-06 |
2015-05-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Alk antibodies, conjugates, and chimeric antigen receptors, and their use
|
|
CN105899232A
(zh)
*
|
2013-11-13 |
2016-08-24 |
诺华股份有限公司 |
用于增强免疫应答的mTOR抑制剂
|
|
WO2015077717A1
(en)
|
2013-11-25 |
2015-05-28 |
The Broad Institute Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
|
|
US10246505B2
(en)
|
2013-11-25 |
2019-04-02 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptors to control HIV infection
|
|
WO2015085147A1
(en)
|
2013-12-05 |
2015-06-11 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
|
JP6943568B2
(ja)
|
2013-12-06 |
2021-10-06 |
アメリカ合衆国 |
胸腺間質性リンパ球新生因子受容体特異的キメラ抗原受容体及びそれを使用する方法
|
|
ES2918501T3
(es)
|
2013-12-19 |
2022-07-18 |
Novartis Ag |
Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
|
|
US10287354B2
(en)
|
2013-12-20 |
2019-05-14 |
Novartis Ag |
Regulatable chimeric antigen receptor
|
|
EP3082853A2
(en)
|
2013-12-20 |
2016-10-26 |
The Broad Institute, Inc. |
Combination therapy with neoantigen vaccine
|
|
CN113354744A
(zh)
|
2013-12-20 |
2021-09-07 |
弗雷德哈钦森癌症研究中心 |
带标签的嵌合效应分子及其受体
|
|
WO2015092024A2
(en)
*
|
2013-12-20 |
2015-06-25 |
Cellectis |
Method of engineering multi-input signal sensitive t cell for immunotherapy
|
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
|
US20160333108A1
(en)
*
|
2014-01-13 |
2016-11-17 |
Stephen J. Forman |
CHIMERIC ANTIGEN RECEPTORS (CARs) HAVING MUTATIONS IN THE FC SPACER REGION AND METHODS FOR THEIR USE
|
|
US11028143B2
(en)
|
2014-01-21 |
2021-06-08 |
Novartis Ag |
Enhanced antigen presenting ability of RNA CAR T cells by co-introduction of costimulatory molecules
|
|
SG10201900002QA
(en)
|
2014-01-24 |
2019-02-27 |
Dana Farber Cancer Institue Inc |
Antibody molecules to pd-1 and uses thereof
|
|
EP3099717B1
(en)
|
2014-01-31 |
2019-03-27 |
Novartis AG |
Antibody molecules to tim-3 and uses thereof
|
|
ES2792849T3
(es)
*
|
2014-02-10 |
2020-11-12 |
Univ Emory |
Expresión de polipéptido químico con receptores de linfocitos variables en células inmunes y usos para tratar el cáncer
|
|
ES3063961T3
(en)
*
|
2014-02-14 |
2026-04-21 |
Cellectis |
Cells for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells
|
|
EP3656864A1
(en)
|
2014-02-14 |
2020-05-27 |
Board of Regents, The University of Texas System |
Chimeric antigen receptors and methods of making
|
|
US10934346B2
(en)
*
|
2014-02-14 |
2021-03-02 |
Bellicum Pharmaceuticals, Inc. |
Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12
|
|
CA2939093A1
(en)
|
2014-02-14 |
2015-08-20 |
Immune Design Corp. |
Immunotherapy of cancer through combination of local and systemic immune stimulation
|
|
US10196608B2
(en)
|
2014-02-21 |
2019-02-05 |
Cellectis |
Method for in situ inhibition of regulatory T cells
|
|
PE20161209A1
(es)
|
2014-02-21 |
2016-11-10 |
Abbvie Stemcentrx Llc |
Conjugados de anticuerpos anti-drosophila similar a delta 3 (anti-dll3) y medicamentos para usarse en el tratamiento contra melanoma
|
|
CN106279434B
(zh)
*
|
2014-02-24 |
2020-07-03 |
西比曼生物科技(上海)有限公司 |
工程化cd20靶向性的nkt细胞及其制备方法和应用
|
|
JP2017507950A
(ja)
|
2014-02-27 |
2017-03-23 |
リセラ・コーポレイションLycera Corporation |
レチノイン酸受容体関連オーファン受容体ガンマのアゴニストを使用する養子細胞療法及び関連治療方法
|
|
CN104877028A
(zh)
*
|
2014-02-28 |
2015-09-02 |
百奥迈科生物技术有限公司 |
抗dota嵌合抗原受体修饰的t细胞及其抗肿瘤的应用
|
|
CN112094347A
(zh)
*
|
2014-03-05 |
2020-12-18 |
奥托路斯有限公司 |
具有针对T细胞受体beta恒定区的抗原结合域的嵌合抗原受体(CAR)
|
|
US20230027993A1
(en)
|
2014-03-05 |
2023-01-26 |
Autolus Limited |
Methods
|
|
US11385233B2
(en)
|
2015-03-05 |
2022-07-12 |
Autolus Limited |
Methods of depleting malignant T-cells
|
|
GB201403972D0
(en)
|
2014-03-06 |
2014-04-23 |
Ucl Business Plc |
Chimeric antigen receptor
|
|
US20150259420A1
(en)
|
2014-03-14 |
2015-09-17 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
|
EP3593812A3
(en)
|
2014-03-15 |
2020-05-27 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor
|
|
WO2015143224A1
(en)
*
|
2014-03-19 |
2015-09-24 |
Ambrx, Inc. |
Chimeric antigen receptor-modified t-cells
|
|
CA2943008C
(en)
*
|
2014-03-19 |
2021-03-30 |
Cellectis |
Cd123 specific chimeric antigen receptors for cancer immunotherapy
|
|
TWI731535B
(zh)
|
2014-03-21 |
2021-06-21 |
美商艾伯維有限公司 |
抗-egfr抗體及抗體藥物結合物
|
|
EP3126390B2
(en)
*
|
2014-04-03 |
2026-01-07 |
Cellectis |
Cd33 specific chimeric antigen receptors for cancer immunotherapy
|
|
AU2015244039B2
(en)
|
2014-04-07 |
2021-10-21 |
Novartis Ag |
Treatment of cancer using anti-CD19 chimeric antigen receptor
|
|
CN106414726A
(zh)
|
2014-04-07 |
2017-02-15 |
米纳瓦生物技术公司 |
抗nme抗体
|
|
CA2945320A1
(en)
|
2014-04-10 |
2015-10-15 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Drug regulated transgene expression
|
|
WO2015158671A1
(en)
*
|
2014-04-14 |
2015-10-22 |
Cellectis |
Bcma (cd269) specific chimeric antigen receptors for cancer immunotherapy
|
|
RU2763795C2
(ru)
|
2014-04-23 |
2022-01-11 |
Джуно Терапьютикс, Инк. |
Способы выделения, культивирования и генетической инженерии популяций клеток иммунной системы для адоптивной терапии
|
|
NZ725201A
(en)
|
2014-04-25 |
2018-05-25 |
Bluebird Bio Inc |
Improved methods for manufacturing adoptive cell therapies
|
|
US20170049819A1
(en)
*
|
2014-04-25 |
2017-02-23 |
Bluebird Bio, Inc. |
Kappa/lambda chimeric antigen receptors
|
|
LT3134432T
(lt)
*
|
2014-04-25 |
2020-04-10 |
Bluebird Bio, Inc. |
Mnd promotorius chimerinių antigenų receptoriams
|
|
WO2015167766A1
(en)
*
|
2014-04-29 |
2015-11-05 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Ccr5 disruption of cells expressing anti-hiv chimeric antigen receptor (car) derived from broadly neutralizing antibodies
|
|
DK3166968T3
(da)
*
|
2014-05-02 |
2021-12-06 |
Univ Pennsylvania |
Sammensætninger og fremgangsmåder til kimæriske autoantistofreceptor-T-celler
|
|
GB201407852D0
(en)
|
2014-05-02 |
2014-06-18 |
Iontas Ltd |
Preparation of libraries od protein variants expressed in eukaryotic cells and use for selecting binding molecules
|
|
CN106459173A
(zh)
|
2014-05-02 |
2017-02-22 |
爱默蕾大学 |
人源化可变淋巴细胞受体(vlr)及其相关组合物和用途
|
|
JP6523337B2
(ja)
|
2014-05-05 |
2019-05-29 |
リセラ・コーポレイションLycera Corporation |
RORγのアゴニストとしての使用及び疾患治療のためのベンゼンスルホンアミド及び関連化合物
|
|
US9896441B2
(en)
|
2014-05-05 |
2018-02-20 |
Lycera Corporation |
Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease
|
|
JP6682509B2
(ja)
*
|
2014-05-14 |
2020-04-15 |
カースゲン セラピューティクス リミテッドCarsgen Therapeutics Limited |
キメラ抗原受容体タンパク質をコードする核酸およびキメラ抗原受容体タンパク質を発現するtリンパ球
|
|
AU2015259877B2
(en)
|
2014-05-15 |
2021-02-25 |
National University Of Singapore |
Modified natural killer cells and uses thereof
|
|
US11041021B2
(en)
|
2014-05-23 |
2021-06-22 |
University Of Florida Research Foundation, Incorporated |
Car based immunotherapy
|
|
MX383150B
(es)
|
2014-06-02 |
2025-03-13 |
Us Health |
Receptores quiméricos de antígeno que tienen como diana a cd-19.
|
|
SI3151672T1
(sl)
|
2014-06-06 |
2021-03-31 |
Bluebird Bio, Inc. |
Izboljšani T-celični sestavki
|
|
AU2015276131A1
(en)
*
|
2014-06-17 |
2016-11-17 |
Cellectis |
CD123 specific multi-chain chimeric antigen receptor
|
|
GB201506423D0
(en)
*
|
2015-04-15 |
2015-05-27 |
Tc Biopharm Ltd |
Gamma delta T cells and uses thereof
|
|
AU2015289644A1
(en)
|
2014-07-15 |
2017-02-02 |
Juno Therapeutics, Inc. |
Engineered cells for adoptive cell therapy
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
KR20170037625A
(ko)
|
2014-07-21 |
2017-04-04 |
노파르티스 아게 |
Cll-1 키메라 항원 수용체를 사용한 암의 치료
|
|
SG10201913765YA
(en)
|
2014-07-21 |
2020-03-30 |
Novartis Ag |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
TWI750110B
(zh)
|
2014-07-21 |
2021-12-21 |
瑞士商諾華公司 |
使用人類化抗-bcma嵌合抗原受體治療癌症
|
|
WO2016014530A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
MX2017001079A
(es)
|
2014-07-24 |
2017-09-12 |
Bluebird Bio Inc |
Receptores de antígeno quiméricos de antígeno de maduración de células b (bcma).
|
|
MX2017001229A
(es)
*
|
2014-07-29 |
2017-05-01 |
Pfizer |
Receptores de antigenos quimericos especificos de egfrviii para inmunoterapia de cancer.
|
|
KR102048855B1
(ko)
*
|
2014-07-29 |
2019-11-26 |
셀렉티스 |
암 면역요법을 위한 ror1(ntrkr1) 특이적 키메라 항원 수용체
|
|
ES2781175T3
(es)
|
2014-07-31 |
2020-08-31 |
Novartis Ag |
Subconjunto optimizado de células T que contienen un receptor de antígeno quimérico
|
|
JP2017522893A
(ja)
|
2014-07-31 |
2017-08-17 |
セレクティスCellectis |
Ror1特異的多重鎖キメラ抗原受容体
|
|
CA2958200A1
(en)
|
2014-08-14 |
2016-02-18 |
Novartis Ag |
Treatment of cancer using a gfr alpha-4 chimeric antigen receptor
|
|
ES2791248T3
(es)
|
2014-08-19 |
2020-11-03 |
Novartis Ag |
Receptor antigénico quimérico (CAR) anti-CD123 para su uso en el tratamiento del cáncer
|
|
AU2015308899B2
(en)
|
2014-08-27 |
2020-05-28 |
Dana-Farber Cancer Institute, Inc. |
Intracellular osteopontin regulates the lineage commitment of lymphoid subsets
|
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
EP2990416B1
(en)
*
|
2014-08-29 |
2018-06-20 |
GEMoaB Monoclonals GmbH |
Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders
|
|
JP7080053B2
(ja)
|
2014-08-29 |
2022-06-03 |
ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム |
腫瘍の治療のための、キヌレニンを枯渇させる酵素の投与
|
|
US10888608B2
(en)
|
2014-09-02 |
2021-01-12 |
Bellicum Pharmaceuticals, Inc. |
Costimulation of chimeric antigen receptors by MyD88 and CD40 polypeptides
|
|
ES2777305T5
(en)
*
|
2014-09-04 |
2025-09-30 |
Cellectis |
Trophoblast glycoprotein (5t4, tpbg) specific chimeric antigen receptors for cancer immunotherapy
|
|
US20180133252A9
(en)
*
|
2014-09-09 |
2018-05-17 |
Unum Therapeutics Inc. |
Chimeric receptors and uses thereof in immune therapy
|
|
ES2771926T3
(es)
|
2014-09-13 |
2020-07-07 |
Novartis Ag |
Terapias de combinación
|
|
KR20250067191A
(ko)
|
2014-09-17 |
2025-05-14 |
노파르티스 아게 |
입양 면역요법을 위한 키메라 수용체에 의한 세포독성 세포의 표적화
|
|
JP6613304B2
(ja)
|
2014-09-17 |
2019-12-04 |
ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
抗cd276抗体(b7h3)
|
|
CN107002084B
(zh)
*
|
2014-09-19 |
2021-09-10 |
希望之城公司 |
靶向IL13Rα2的共刺激嵌合抗原受体T细胞
|
|
US10259855B2
(en)
*
|
2014-10-02 |
2019-04-16 |
The Wistar Institute Of Anatomy And Biology |
Methods and compositions for treating cancer
|
|
AU2015327868A1
(en)
|
2014-10-03 |
2017-04-20 |
Novartis Ag |
Combination therapies
|
|
JP2017531430A
(ja)
*
|
2014-10-07 |
2017-10-26 |
セレクティスCellectis |
Carによって誘導される免疫細胞の活性を調節するための方法
|
|
KR20170068504A
(ko)
|
2014-10-08 |
2017-06-19 |
노파르티스 아게 |
키메라 항원 수용체 요법에 대한 치료 반응성을 예측하는 바이오마커 및 그의 용도
|
|
MY167722A
(en)
*
|
2014-10-09 |
2018-09-21 |
Univ Yamaguchi |
Car expression vector and car-expressing t cells
|
|
ES2753391T3
(es)
|
2014-10-14 |
2020-04-08 |
Halozyme Inc |
Composiciones de adenosina desaminasa 2 (ADA2), variantes de la misma y métodos de uso de las mismas
|
|
BR112017008042A2
(pt)
*
|
2014-10-20 |
2017-12-26 |
Juno Therapeutics Inc |
métodos e composições para dosagem em terapia de célula adotiva
|
|
JP6882978B2
(ja)
|
2014-10-29 |
2021-06-02 |
バイスクルアールディー・リミテッド |
Mt1−mmpに特異的な二環性ペプチドリガンド
|
|
CN107106609A
(zh)
|
2014-10-31 |
2017-08-29 |
宾夕法尼亚大学董事会 |
刺激和扩展t细胞的组合物和方法
|
|
WO2016069282A1
(en)
|
2014-10-31 |
2016-05-06 |
The Trustees Of The University Of Pennsylvania |
Altering gene expression in modified t cells and uses thereof
|
|
CA2964783C
(en)
|
2014-11-05 |
2024-01-23 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptors (car) to selectively target protein complexes
|
|
CN107109438B
(zh)
|
2014-11-05 |
2021-09-03 |
朱诺治疗学股份有限公司 |
用于转导及细胞处理的方法
|
|
AU2015343013B2
(en)
|
2014-11-05 |
2020-07-16 |
Board Of Regents, The University Of Texas System |
Gene modified immune effector cells and engineered cells for expansion of immune effector cells
|
|
WO2016073748A1
(en)
*
|
2014-11-05 |
2016-05-12 |
Board Of Regents, The University Of Texas System |
Biomarkers and targets for cancer immunotherapy
|
|
US9879087B2
(en)
|
2014-11-12 |
2018-01-30 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
|
IL313511A
(en)
*
|
2014-11-12 |
2024-08-01 |
Seagen Inc |
Compounds acting on glycans and methods of using them
|
|
CN105601746B
(zh)
*
|
2014-11-21 |
2021-02-19 |
三生国健药业(上海)股份有限公司 |
一种嵌合Fc受体的融合蛋白及其制备方法和应用
|
|
CA2969456A1
(en)
|
2014-12-03 |
2016-06-09 |
Juno Therapeutics, Inc. |
Methods and compositions for adoptive cell therapy
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
AU2015357526B2
(en)
|
2014-12-05 |
2022-03-17 |
Eureka Therapeutics, Inc. |
Chimeric antigen receptors targeting B-cell maturation antigen and uses thereof
|
|
EP3227324A4
(en)
|
2014-12-05 |
2018-08-29 |
Memorial Sloan Kettering Cancer Center |
Antibodies targeting g-protein coupled receptor and methods of use
|
|
BR112017011893A2
(pt)
|
2014-12-05 |
2018-07-24 |
City Of Hope |
células t modificadas no receptor de antígeno quimérico direcionado para cs1
|
|
KR20240135036A
(ko)
|
2014-12-05 |
2024-09-10 |
메모리얼 슬로안 케터링 캔서 센터 |
B-세포 성숙화 항원을 표적화하는 항체 및 사용 방법
|
|
SI3227339T1
(sl)
|
2014-12-05 |
2022-02-28 |
Memorial Sloan-Kettering Cancer Center |
Himerni antigenski receptorji, ki ciljajo na receptor, povezan z G-proteinom, in njihova uporaba
|
|
CN113968913A
(zh)
*
|
2014-12-08 |
2022-01-25 |
美国卫生和人力服务部 |
抗cd70嵌合抗原受体
|
|
HK1245326A1
(zh)
|
2014-12-12 |
2018-08-24 |
Voyager Therapeutics, Inc. |
用於生产scaav的组合物和方法
|
|
EA036379B1
(ru)
|
2014-12-12 |
2020-11-02 |
Блубёрд Био, Инк. |
Химерные антигенные рецепторы к bcma
|
|
EP4400516A1
(en)
|
2014-12-15 |
2024-07-17 |
The Regents of the University of California |
Bispecific or-gate chimeric antigen receptor responsive to cd19 and cd20
|
|
EP3234120B1
(en)
|
2014-12-15 |
2025-09-03 |
The Regents of the University of California |
Cytotoxic molecules responsive to intracellular ligands for selective t cell mediated killing
|
|
US10993997B2
(en)
|
2014-12-19 |
2021-05-04 |
The Broad Institute, Inc. |
Methods for profiling the t cell repertoire
|
|
US10975442B2
(en)
|
2014-12-19 |
2021-04-13 |
Massachusetts Institute Of Technology |
Molecular biomarkers for cancer immunotherapy
|
|
KR102376244B1
(ko)
*
|
2014-12-24 |
2022-03-21 |
오토러스 리미티드 |
세포
|
|
CA3197849A1
(en)
*
|
2014-12-29 |
2016-07-07 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
MA41346A
(fr)
|
2015-01-12 |
2017-11-21 |
Juno Therapeutics Inc |
Eléments régulateurs post-transcriptionnels d'hépatite modifiée
|
|
WO2016115482A1
(en)
|
2015-01-16 |
2016-07-21 |
Novartis Pharma Ag |
Phosphoglycerate kinase 1 (pgk) promoters and methods of use for expressing chimeric antigen receptor
|
|
JP6865688B2
(ja)
|
2015-01-16 |
2021-04-28 |
ジュノー セラピューティクス インコーポレイテッド |
Ror1に特異的な抗体およびキメラ抗原受容体
|
|
ES2869972T3
(es)
|
2015-01-26 |
2021-10-26 |
Cellectis |
Sistemas de receptores de antígenos quiméricos dirigidos por mAb para clasificar/agotar células inmunitarias genomanipuladas
|
|
CN113862292B
(zh)
*
|
2015-01-29 |
2024-12-27 |
明尼苏达大学董事会 |
嵌合抗原受体、组合物以及方法
|
|
US11161907B2
(en)
|
2015-02-02 |
2021-11-02 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
CN113713091A
(zh)
*
|
2015-02-06 |
2021-11-30 |
新加坡国立大学 |
工程免疫细胞及其用途和生产方法
|
|
JP6724023B2
(ja)
|
2015-02-09 |
2020-07-15 |
リサーチ ディベロップメント ファウンデーション |
改善された補体活性化を示す操作された免疫グロブリンfcポリペプチド
|
|
US20160228544A1
(en)
*
|
2015-02-11 |
2016-08-11 |
Ensysce Biosciences, Inc. |
Single Walled Carbon Nanotube Polynucleotide Complexes and Methods Related Thereto
|
|
WO2016134284A1
(en)
*
|
2015-02-19 |
2016-08-25 |
University Of Florida Research Foundation, Inc. |
Chimeric antigen receptors and uses thereof
|
|
CN107530424A
(zh)
|
2015-02-20 |
2018-01-02 |
俄亥俄州国家创新基金会 |
针对nkg2d和肿瘤相关抗原的二价抗体
|
|
MA41613A
(fr)
*
|
2015-02-23 |
2018-01-02 |
Abbvie Stemcentrx Llc |
Récepteurs antigéniques chimériques anti-dll3 et procédés d'utilisation desdits récepteurs
|
|
WO2016138034A1
(en)
|
2015-02-24 |
2016-09-01 |
The Regents Of The University Of California |
Binding-triggered transcriptional switches and methods of use thereof
|
|
EP3804741A3
(en)
|
2015-02-24 |
2021-07-14 |
Board of Regents, The University of Texas System |
Selection methods for genetically-modified t cells
|
|
JP7237449B2
(ja)
*
|
2015-02-27 |
2023-03-13 |
アイセル・ジーン・セラピューティクス・エルエルシー |
血液系腫瘍を標的としたキメラ抗体受容体(CARs)の構成およびその使用方法
|
|
KR102133857B1
(ko)
*
|
2015-03-02 |
2020-07-20 |
이노베이티브 셀룰러 테라퓨틱스 코퍼레이션 리미티드 |
Pd-l1에 의해 유도된 면역관용의 감소
|
|
US10195272B2
(en)
|
2015-03-02 |
2019-02-05 |
The Nemours Foundation |
Adoptive t-cell therapy using FcεRI-based chimeric antigen receptors for treating IgE-mediated allergic diseases
|
|
CA2978186A1
(en)
*
|
2015-03-05 |
2016-09-09 |
Fred Hutchinson Cancer Research Center |
Immunomodulatory fusion proteins and uses thereof
|
|
WO2016145298A1
(en)
|
2015-03-12 |
2016-09-15 |
The Regents Of The University Of California |
METHODS FOR TREATING CANCER WITH RORgamma INHIBITORS
|
|
WO2016149254A1
(en)
*
|
2015-03-17 |
2016-09-22 |
Chimera Bioengineering, Inc. |
Smart car devices, de car polypeptides, side cars and uses thereof
|
|
US10738116B2
(en)
|
2015-03-19 |
2020-08-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Dual specific anti-CD22-anti-CD19 chimeric antigen receptors
|
|
ES2789348T3
(es)
|
2015-03-20 |
2020-10-26 |
Us Health |
Anticuerpos neutralizantes para GP120 y sus usos
|
|
WO2016154621A1
(en)
|
2015-03-26 |
2016-09-29 |
The California Institute For Biomedical Research |
SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
|
|
AU2016243124A1
(en)
|
2015-03-27 |
2017-11-02 |
University Of Southern California |
CAR T-cell therapy directed to LHR for the treatment of solid tumors
|
|
US20190119385A1
(en)
*
|
2015-03-27 |
2019-04-25 |
University Of Southern California |
Hla-g as a novel target for car t-cell immunotherapy
|
|
US11261232B2
(en)
*
|
2015-04-02 |
2022-03-01 |
Memorial Sloan Kettering Cancer Center |
TNFRSF14 / HVEM proteins and methods of use thereof
|
|
AU2016243026B2
(en)
|
2015-04-03 |
2022-03-31 |
Eureka Therapeutics, Inc. |
Constructs targeting AFP peptide/MHC complexes and uses thereof
|
|
RS61907B1
(sr)
|
2015-04-06 |
2021-06-30 |
Subdomain Llc |
Polipeptidi koji sadrže de novo vezujući domen i njihova primena
|
|
AU2016246457B2
(en)
|
2015-04-06 |
2020-10-15 |
Cytoimmune Therapeutics, Inc. |
EGFR-directed car therapy for glioblastoma
|
|
MX2017012939A
(es)
|
2015-04-08 |
2018-05-22 |
Novartis Ag |
Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19.
|
|
WO2016168773A2
(en)
|
2015-04-15 |
2016-10-20 |
The California Institute For Biomedical Research |
Optimized pne-based chimeric receptor t cell switches and uses thereof
|
|
WO2016166568A1
(en)
|
2015-04-16 |
2016-10-20 |
Juno Therapeutics Gmbh |
Methods, kits and apparatus for expanding a population of cells
|
|
SG11201708516YA
(en)
|
2015-04-17 |
2017-11-29 |
David Maxwell Barrett |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
EP3283508B1
(en)
|
2015-04-17 |
2021-03-17 |
Alpine Immune Sciences, Inc. |
Immunomodulatory proteins with tunable affinities
|
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
EP3288638A1
(en)
|
2015-04-25 |
2018-03-07 |
The General Hospital Corporation |
Anti-fugetactic agent and anti-cancer agent combination therapy and compositions for the treatment of cancer
|
|
EP3288570A4
(en)
|
2015-04-29 |
2018-11-21 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
|
WO2016176651A2
(en)
*
|
2015-04-29 |
2016-11-03 |
Fred Hutchinson Cancer Research Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
GB201507368D0
(en)
|
2015-04-30 |
2015-06-17 |
Ucl Business Plc |
Cell
|
|
WO2016176639A1
(en)
*
|
2015-04-30 |
2016-11-03 |
University Of Southern California |
Secretory tnt car cell immunotherapy
|
|
WO2016174652A1
(en)
|
2015-04-30 |
2016-11-03 |
Technion Research & Development Foundation Limited |
Chimeric antigen receptors and methods of their use
|
|
US10925972B2
(en)
|
2015-05-01 |
2021-02-23 |
The Regents Of The University Of California |
Glycan-dependent immunotherapeutic molecules
|
|
JP2018515491A
(ja)
|
2015-05-05 |
2018-06-14 |
リセラ・コーポレイションLycera Corporation |
RORγの作動薬及び疾患の療法として使用するジヒドロ−2H−ベンゾ[b][1,4]オキサジンスルホンアミド及び関連化合物
|
|
CN107667173A
(zh)
|
2015-05-06 |
2018-02-06 |
斯尼普技术有限公司 |
改变微生物种群和改善微生物群
|
|
EP3294342A4
(en)
|
2015-05-08 |
2018-11-07 |
President and Fellows of Harvard College |
Universal donor stem cells and related methods
|
|
US20200316231A1
(en)
*
|
2015-05-10 |
2020-10-08 |
The Trustees Of The University Of Pennsylvania |
Compositions And Methods For Imaging Immune Cells
|
|
US11253616B2
(en)
|
2017-09-06 |
2022-02-22 |
The Trustees Of The University Of Pennsylvania |
Small molecules for dual function positron emission tomography (PET) and cell suicide switches
|
|
WO2016180467A1
(en)
*
|
2015-05-11 |
2016-11-17 |
Biontech Cell & Gene Therapies Gmbh |
Enhancing the effect of car-engineered t cells by means of nucleic acid vaccination
|
|
EP3294773A1
(en)
|
2015-05-15 |
2018-03-21 |
The General Hospital Corporation |
Antagonistic anti-tumor necrosis factor receptor superfamily antibodies
|
|
CN107995913B
(zh)
|
2015-05-18 |
2022-02-11 |
T细胞受体治疗公司 |
使用融合蛋白对tcr重编程的组合物和方法
|
|
CN108137669B
(zh)
*
|
2015-05-18 |
2023-02-17 |
优瑞科生物技术公司 |
抗ror1嵌合抗原受体
|
|
US10434153B1
(en)
|
2015-05-20 |
2019-10-08 |
Kim Leslie O'Neill |
Use of car and bite technology coupled with an scFv from an antibody against human thymidine kinase 1 to specifically target tumors
|
|
US10752670B2
(en)
|
2015-05-20 |
2020-08-25 |
Cellectis |
Anti-GD3 specific chimeric antigen receptors for cancer immunotherapy
|
|
TW202523682A
(zh)
|
2015-05-20 |
2025-06-16 |
美商博德研究所有限公司 |
共有之gata3相關之腫瘤特異性新抗原
|
|
HK1245095A1
(zh)
|
2015-05-20 |
2018-08-24 |
Novartis Ag |
依维莫司(everolimus)与达托里昔布(dactolisib)的医药组合
|
|
CA2986755A1
(en)
*
|
2015-05-28 |
2016-12-01 |
Armo Biosciences, Inc. |
Pegylated interleukin-10 for use in treating cancer
|
|
IL295224B2
(en)
|
2015-05-28 |
2025-07-01 |
Kite Pharma Inc |
Methods of conditioning patients for t cell therapy
|
|
MX388325B
(es)
|
2015-05-28 |
2025-03-19 |
Kite Pharma Inc |
Metodos de diagnostico para tratamiento con linfocitos t.
|
|
JP6949728B2
(ja)
|
2015-05-29 |
2021-10-13 |
ジュノー セラピューティクス インコーポレイテッド |
遺伝子操作された細胞における阻害相互作用を調節するための組成物および方法
|
|
EP3303381A1
(en)
|
2015-05-29 |
2018-04-11 |
Fred Hutchinson Cancer Research Center |
Compositions for cellular immunotherapy
|
|
AU2016271124C1
(en)
|
2015-05-30 |
2020-05-14 |
Molecular Templates, Inc. |
De-immunized, Shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same
|
|
JP7010473B2
(ja)
|
2015-06-04 |
2022-02-10 |
ユニバーシティ オブ サザン カリフォルニア |
Lym-1およびlym-2標的化car細胞免疫療法
|
|
US20160355777A1
(en)
*
|
2015-06-05 |
2016-12-08 |
Novartis Ag |
Flow-through paramagnetic particle-based cell separation and paramagnetic particle removal
|
|
KR20180023949A
(ko)
|
2015-06-09 |
2018-03-07 |
메모리얼 슬로안-케터링 캔서 센터 |
인간 hla에 의해 제시된 ebv 잠복성 막 단백질 2a 펩티드에 특이적인 t 세포 수용체-유사 항체 작용제
|
|
EP4424326A3
(en)
|
2015-06-10 |
2024-11-13 |
ImmunityBio, Inc. |
Modified nk-92 cells for treating cancer
|
|
KR20180025894A
(ko)
|
2015-06-11 |
2018-03-09 |
라이세라 코퍼레이션 |
Rory의 작용제로서 사용하기 위한 아릴 디히드로-2h-벤조[b][1,4]옥사진 술폰아미드 및 관련 화합물 및 질환의 치료
|
|
CN105177031B
(zh)
*
|
2015-06-12 |
2018-04-24 |
北京艺妙神州医疗科技有限公司 |
嵌合抗原受体修饰的t细胞及其用途
|
|
CN107708741A
(zh)
*
|
2015-06-12 |
2018-02-16 |
免疫医疗公司 |
用嵌合抗原受体(car)构建体和表达car构建体的t细胞(car‑t)或nk细胞(car‑nk)进行的疾病疗法
|
|
US10639329B2
(en)
|
2015-06-12 |
2020-05-05 |
Lentigen Technology, Inc. |
Method to treat cancer with engineered T-cells
|
|
CA3012607A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Crispr enzymes and systems
|
|
FI3909972T3
(fi)
|
2015-06-19 |
2024-05-03 |
Sebastian Kobold |
Pd1-cd28-fuusioproteiineja ja niiden käyttö lääkkeessä
|
|
TWI833684B
(zh)
|
2015-06-25 |
2024-03-01 |
美商生物細胞基因治療有限公司 |
嵌合抗原受體(car)、組合物及其使用方法
|
|
US11173179B2
(en)
|
2015-06-25 |
2021-11-16 |
Icell Gene Therapeutics Llc |
Chimeric antigen receptor (CAR) targeting multiple antigens, compositions and methods of use thereof
|
|
US12577289B2
(en)
|
2015-06-30 |
2026-03-17 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Surrogate co-receptors for t cells and methods of use
|
|
WO2017004252A1
(en)
|
2015-06-30 |
2017-01-05 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Redirected cells with mhc chimeric receptors and methods of use in immunotherapy
|
|
EP3320087A4
(en)
*
|
2015-07-08 |
2019-01-23 |
The Johns Hopkins University |
BONE MARROW FILTRATION LYMPHOCYTES (MILS) AS A T-CELL SOURCE FOR CHIMERIC ANTIGEN RECEPTOR (CAR) THERAPY
|
|
US11116795B2
(en)
*
|
2015-07-10 |
2021-09-14 |
The Trustees Of The University Of Pennsylvania |
Treatment of a canine CD20 positive disease or condition using a canine CD20-specific chimeric antigen receptor
|
|
EP3322801A1
(en)
|
2015-07-15 |
2018-05-23 |
Juno Therapeutics, Inc. |
Engineered cells for adoptive cell therapy
|
|
AU2016297014B2
(en)
|
2015-07-21 |
2021-06-17 |
Novartis Ag |
Methods for improving the efficacy and expansion of immune cells
|
|
WO2018126369A1
(en)
|
2017-01-05 |
2018-07-12 |
Shanghai Sidansai Biotechnology Co., Ltd |
Humanized anti-cd19 antibody and use thereof with chimeric antigen receptor
|
|
US10493139B2
(en)
|
2015-07-24 |
2019-12-03 |
Innovative Cellular Therapeutics CO., LTD. |
Humanized anti-CD19 antibody and use thereof with chimeric antigen receptor
|
|
RU2766690C2
(ru)
|
2015-07-28 |
2022-03-15 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Модифицированные моноциты/макрофаги, экспрессирующие химерные антигенные рецепторы, и их применения
|
|
DK3317301T3
(da)
|
2015-07-29 |
2021-06-28 |
Immutep Sas |
Kombinationsterapier omfattende antistofmolekyler mod lag-3
|
|
GB2592821B
(en)
|
2015-07-31 |
2022-01-12 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
KR102011789B1
(ko)
*
|
2015-08-05 |
2019-08-19 |
주식회사 셀랩메드 |
키메라 항원 수용체 및 키메라 항원 수용체가 발현된 t 세포
|
|
WO2017027291A1
(en)
|
2015-08-07 |
2017-02-16 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Bispecific car t-cells for solid tumor targeting
|
|
EP3331913A1
(en)
|
2015-08-07 |
2018-06-13 |
Novartis AG |
Treatment of cancer using chimeric cd3 receptor proteins
|
|
US11286531B2
(en)
|
2015-08-11 |
2022-03-29 |
The Johns Hopkins University |
Assaying ovarian cyst fluid
|
|
US11352439B2
(en)
|
2015-08-13 |
2022-06-07 |
Kim Leslie O'Neill |
Macrophage CAR (MOTO-CAR) in immunotherapy
|
|
CN106467906B
(zh)
*
|
2015-08-20 |
2019-09-27 |
北京马力喏生物科技有限公司 |
构建体、转基因淋巴细胞及其制备方法和用途
|
|
US10976232B2
(en)
|
2015-08-24 |
2021-04-13 |
Gpb Scientific, Inc. |
Methods and devices for multi-step cell purification and concentration
|
|
WO2017040324A1
(en)
*
|
2015-08-28 |
2017-03-09 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for cells expressing a chimeric intracellular signaling molecule
|
|
US11649435B2
(en)
*
|
2015-08-28 |
2023-05-16 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for cells expressing a chimeric intracellular signaling molecule
|
|
US10526408B2
(en)
|
2015-08-28 |
2020-01-07 |
Research Development Foundation |
Engineered antibody FC variants
|
|
US11279769B2
(en)
|
2015-08-31 |
2022-03-22 |
Helixmith Co., Ltd |
Anti-Sialyl Tn chimeric antigen receptors
|
|
JP6905163B2
(ja)
|
2015-09-03 |
2021-07-21 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
サイトカイン放出症候群を予測するバイオマーカー
|
|
EP3347474B1
(en)
*
|
2015-09-11 |
2020-11-04 |
Biosceptre (UK) Limited |
Chimeric antigen receptors and uses thereof
|
|
ES2980794T3
(es)
|
2015-09-15 |
2024-10-03 |
Acerta Pharma Bv |
Combinaciones terapéuticas de un inhibidor de CD19 y un inhibidor de BTK
|
|
CN108348545A
(zh)
*
|
2015-09-18 |
2018-07-31 |
综合医院公司以麻省总医院名义经营 |
具有抗趋除特性的修饰的t细胞及其用途
|
|
US11890348B2
(en)
|
2015-09-18 |
2024-02-06 |
The General Hospital Corporation |
Localized delivery of anti-fugetactic agent for treatment of cancer
|
|
WO2017053556A1
(en)
|
2015-09-22 |
2017-03-30 |
The Trustees Of The University Of Pennsylvania |
Method of redirecting t cells to treat hiv infection
|
|
AU2016326738B2
(en)
|
2015-09-24 |
2023-08-31 |
Abvitro Llc |
HIV antibody compositions and methods of use
|
|
JP7341661B2
(ja)
|
2015-09-25 |
2023-09-11 |
アブビトロ, エルエルシー |
ネイティブに対合するt細胞受容体配列のt細胞受容体標的識別のための高スループットプロセス
|
|
EP3355937A4
(en)
|
2015-09-28 |
2019-04-17 |
Regents of the University of Minnesota |
CHIMERIC ANTIGEN RECEPTOR (CAR) T CELLS AS THERAPEUTIC INTERVENTIONS AT AUTO AND ALLO IMMUNITY
|
|
WO2017058752A1
(en)
*
|
2015-09-28 |
2017-04-06 |
Trustees Of Dartmouth College |
Chimeric antigen receptor anti-inflammatory cells and methods of use
|
|
BR112018006991A2
(en)
*
|
2015-10-06 |
2018-10-16 |
City Of Hope |
psca-targeted chimeric antigen receptors
|
|
AU2016335750B2
(en)
|
2015-10-07 |
2023-05-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
IL-7R-alpha specific antibodies for treating acute lymphoblastic leukemia
|
|
WO2017059796A1
(en)
|
2015-10-08 |
2017-04-13 |
Shanghai Sidansai Biotechnology Co., Ltd |
Activation and expansion of t cells
|
|
EP4289944A3
(en)
*
|
2015-10-08 |
2024-03-13 |
National University Corporation Tokai National Higher Education and Research System |
Method for preparing genetically-modified t cells which express chimeric antigen receptor
|
|
US12241053B2
(en)
|
2015-10-09 |
2025-03-04 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
|
JP6991134B2
(ja)
*
|
2015-10-09 |
2022-01-12 |
ガーダント ヘルス, インコーポレイテッド |
無細胞dnaを使用する集団ベースの処置レコメンダ
|
|
CN114181960B
(zh)
|
2015-10-09 |
2024-08-23 |
美天施生物科技有限公司 |
嵌合抗原受体和使用方法
|
|
CN105153315B
(zh)
*
|
2015-10-09 |
2019-04-02 |
重庆精准生物技术有限公司 |
免疫抑制受体联合肿瘤抗原嵌合受体及其应用
|
|
CN105924530B
(zh)
*
|
2015-10-13 |
2019-08-06 |
中国人民解放军总医院 |
嵌合抗原受体及其基因和重组表达载体、car20-nkt细胞及其制备方法和应用
|
|
CN106755023A
(zh)
*
|
2015-10-15 |
2017-05-31 |
中国人民解放军军事医学科学院附属医院 |
带安全开关的嵌合抗原受体免疫细胞及其制备方法与应用
|
|
CN108290939B
(zh)
|
2015-10-16 |
2023-01-13 |
纽约市哥伦比亚大学理事会 |
用于抑制谱系特异性抗原的组合物和方法
|
|
AU2016336868B2
(en)
|
2015-10-16 |
2022-04-14 |
Ludwig-Maximilians-Universität München |
CXCR6-transduced T cells for targeted tumor therapy
|
|
EP3365026B1
(en)
|
2015-10-19 |
2021-09-22 |
University of Massachusetts |
Anti-cancer and anti-inflammatory therapeutics and methods thereof
|
|
EP3364969A4
(en)
|
2015-10-20 |
2019-07-10 |
Kite Pharma, Inc. |
METHOD FOR THE PRODUCTION OF T CELLS FOR T CELL THERAPY
|
|
US11248238B2
(en)
|
2015-10-22 |
2022-02-15 |
Juno Therapeutics Gmbh |
Methods, kits, agents and apparatuses for transduction
|
|
SG11201803330WA
(en)
|
2015-10-22 |
2018-05-30 |
Juno Therapeutics Gmbh |
Methods for culturing cells and kits and apparatus for same
|
|
JP7194020B2
(ja)
|
2015-10-22 |
2022-12-21 |
ジュノ セラピューティクス ゲーエムベーハー |
細胞の培養方法ならびにそのためのキットおよび装置
|
|
WO2017070654A1
(en)
*
|
2015-10-23 |
2017-04-27 |
Sorrento Therapeutics, Inc. |
Programmable universal cell receptors and methods of using the same
|
|
CN105132445B
(zh)
*
|
2015-10-23 |
2018-10-02 |
马健颖 |
一种特异识别肿瘤细胞的受体蛋白、t淋巴细胞及nk细胞
|
|
US11059879B2
(en)
|
2015-10-27 |
2021-07-13 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptor molecules and uses thereof
|
|
WO2017075478A2
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by use of immune cell gene signatures
|
|
WO2017075451A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
|
|
WO2017075465A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
|
|
DK3368571T5
(da)
|
2015-10-30 |
2024-09-30 |
Univ California |
Transformerende, vækstfaktor-beta-responsive polypeptider og fremgangsmåder til anvendelse deraf
|
|
EP4074731A1
(en)
*
|
2015-11-04 |
2022-10-19 |
City of Hope |
Chimeric antigen receptors targeting her2
|
|
MX2018005618A
(es)
*
|
2015-11-05 |
2018-08-01 |
Juno Therapeutics Inc |
Receptores quimericos que contienen dominios inductores de traf y composiciones y metodos relacionados.
|
|
US11020429B2
(en)
|
2015-11-05 |
2021-06-01 |
Juno Therapeutics, Inc. |
Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy
|
|
EP3373969A4
(en)
|
2015-11-12 |
2019-08-14 |
Siamab Therapeutics, Inc. |
GLYCANINTERAGING COMPOUNDS AND METHOD OF USE
|
|
CN105331585A
(zh)
*
|
2015-11-13 |
2016-02-17 |
科济生物医药(上海)有限公司 |
携带pd-l1阻断剂的嵌合抗原受体修饰的免疫效应细胞
|
|
AU2016355178B9
(en)
|
2015-11-19 |
2019-05-30 |
Massachusetts Institute Of Technology |
Lymphocyte antigen CD5-like (CD5L)-interleukin 12B (p40) heterodimers in immunity
|
|
CN105384826A
(zh)
*
|
2015-11-19 |
2016-03-09 |
广州熙帝生物科技有限公司 |
表达嵌合抗原受体的脐血有核细胞及其应用
|
|
EP3708587B1
(en)
*
|
2015-11-27 |
2024-05-22 |
Cartherics Pty. Ltd. |
Genetically modified cells and uses thereof
|
|
CN108884140B
(zh)
|
2015-12-03 |
2022-10-25 |
朱诺治疗学股份有限公司 |
修饰的嵌合受体及相关组合物和方法
|
|
CA3007258A1
(en)
|
2015-12-03 |
2017-06-08 |
Mark L. Bonyhadi |
Compositions and methods for reducing immune responses against cell therapies
|
|
EA201891338A1
(ru)
|
2015-12-04 |
2018-12-28 |
Новартис Аг |
Композиции и способы для иммуноонкологии
|
|
US11090373B2
(en)
*
|
2015-12-04 |
2021-08-17 |
The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. |
Antigen-specific T cells for inducing immune tolerance
|
|
EP4012415A3
(en)
|
2015-12-04 |
2022-12-07 |
Juno Therapeutics, Inc. |
Methods and compositions related to toxicity associated with cell therapy
|
|
US11479755B2
(en)
|
2015-12-07 |
2022-10-25 |
2Seventy Bio, Inc. |
T cell compositions
|
|
CN109069426B
(zh)
|
2015-12-14 |
2021-10-29 |
X4 制药有限公司 |
治疗癌症的方法
|
|
WO2017106332A1
(en)
|
2015-12-14 |
2017-06-22 |
X4 Pharmaceuticals, Inc. |
Methods for treating cancer
|
|
EP3393504B1
(en)
|
2015-12-22 |
2025-09-24 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
|
PL3393468T3
(pl)
|
2015-12-22 |
2023-01-23 |
X4 Pharmaceuticals, Inc. |
Metody leczenia niedoboru odporności
|
|
SG11201805449PA
(en)
|
2015-12-28 |
2018-07-30 |
Novartis Ag |
Methods of making chimeric antigen receptor -expressing cells
|
|
AU2016382512A1
(en)
|
2015-12-30 |
2018-07-12 |
Novartis Ag |
Immune effector cell therapies with enhanced efficacy
|
|
JP7068169B2
(ja)
|
2016-01-08 |
2022-05-16 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
条件付活性ヘテロ二量体ポリペプチド及びその使用方法
|
|
GB201600328D0
(en)
|
2016-01-08 |
2016-02-24 |
Univ Oslo Hf |
Anti-CD37 chimeric antigen receptors and immune cells expressing them
|
|
CN105950645A
(zh)
*
|
2016-01-11 |
2016-09-21 |
灏灵赛奥(天津)生物科技有限公司 |
Car-cd19抗原受体的人源化融合基因片段、其构建方法及应用
|
|
WO2017123548A1
(en)
*
|
2016-01-14 |
2017-07-20 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Tumor-specific ifna secretion by car t-cells to reprogram the solid tumor microenvironment
|
|
US11505599B2
(en)
|
2016-01-14 |
2022-11-22 |
Memorial Sloan-Kettering Cancer Center |
T cell receptor-like antibodies specific for Foxp3-derived peptides
|
|
WO2017123911A1
(en)
*
|
2016-01-15 |
2017-07-20 |
The Wistar Institute Of Anatomy And Biology |
Methods and compositions for treating cancer
|
|
EA201891641A1
(ru)
|
2016-01-21 |
2019-01-31 |
Пфайзер Инк. |
Химерные антигенные рецепторы, нацеленные на вариант iii рецептора эпидермального фактора роста
|
|
US10221242B2
(en)
|
2016-01-21 |
2019-03-05 |
Pfizer Inc. |
Antibodies specific for epidermal growth factor receptor variant III and their uses
|
|
CN105567640A
(zh)
*
|
2016-01-27 |
2016-05-11 |
苏州佰通生物科技有限公司 |
一种嵌合抗原受体脂肪干细胞及其制备方法
|
|
HK1258353A1
(zh)
|
2016-02-23 |
2019-11-08 |
Immune Design Corp. |
多基因组逆转录病毒载体制剂及用於制备及使用该制剂的方法和系统
|
|
US11542486B2
(en)
|
2016-03-02 |
2023-01-03 |
Board Of Regents, The University Of Texas System |
Human kynureninase enzyme variants having improved pharmacological properties
|
|
AU2017225733A1
(en)
|
2016-03-04 |
2018-09-27 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (CAR) molecules and uses therefore
|
|
US10563172B2
(en)
|
2016-03-14 |
2020-02-18 |
Wisconsin Alumni Research Foundation |
Methods of T cell expansion and activation
|
|
US20190355459A1
(en)
|
2016-03-16 |
2019-11-21 |
Juno Therapeutics, Inc. |
Methods for adaptive design of a treatment regimen and related treatments
|
|
EP3430548A1
(en)
|
2016-03-16 |
2019-01-23 |
Juno Therapeutics, Inc. |
Methods for determining dosing of a therapeutic agent and related treatments
|
|
KR20240116832A
(ko)
*
|
2016-03-17 |
2024-07-30 |
고쿠리츠다이가쿠호우진 야마구치 다이가쿠 |
면역 기능 제어 인자를 발현하는 면역 담당 세포 및 발현 벡터
|
|
KR102499191B1
(ko)
|
2016-03-18 |
2023-02-13 |
프레드 허친슨 캔서 센터 |
Cd20 면역요법을 위한 조성물 및 방법
|
|
US12590321B2
(en)
|
2016-03-19 |
2026-03-31 |
Exuma Biotech Corp. |
Methods and compositions for genetically modifying and expanding lymphocytes and regulating the activity thereof
|
|
US11325948B2
(en)
|
2016-03-19 |
2022-05-10 |
Exuma Biotech Corp. |
Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
|
|
US11111505B2
(en)
|
2016-03-19 |
2021-09-07 |
Exuma Biotech, Corp. |
Methods and compositions for transducing lymphocytes and regulating the activity thereof
|
|
KR20190021200A
(ko)
|
2016-03-22 |
2019-03-05 |
시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 |
독성을 예방 또는 경감시키기 위한 조기 개재 방법
|
|
US11549099B2
(en)
|
2016-03-23 |
2023-01-10 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
|
CN109219445B
(zh)
*
|
2016-04-01 |
2022-08-26 |
上海煦顼技术有限公司 |
嵌合抗原受体修饰细胞治疗癌症的应用
|
|
KR20200068750A
(ko)
|
2016-04-01 |
2020-06-15 |
카이트 파마 인코포레이티드 |
키메라 수용체 및 그의 사용 방법
|
|
US10654934B2
(en)
|
2016-04-01 |
2020-05-19 |
Innovative Cellular Therapeutics CO., LTD. |
Use of chimeric antigen receptor modified cells to treat cancer
|
|
MY210545A
(en)
|
2016-04-01 |
2025-09-30 |
Kite Pharma Inc |
Chimeric receptors to flt3 and methods of use thereof
|
|
CN109414455B
(zh)
|
2016-04-01 |
2023-01-20 |
凯德药业股份有限公司 |
Bcma结合分子及其使用方法
|
|
PT3436079T
(pt)
*
|
2016-04-01 |
2021-10-06 |
Kite Pharma Inc |
Recetores de antigénios quiméricos e de células t e métodos de uso
|
|
CN108778312B
(zh)
|
2016-04-08 |
2022-07-15 |
爱默蕾大学 |
使用基于细胞的疗法治疗癌症和传染病的方法
|
|
JP7282521B2
(ja)
|
2016-04-08 |
2023-05-29 |
パーデュー・リサーチ・ファウンデイション |
Car t細胞療法のための方法および組成物
|
|
US11337969B2
(en)
|
2016-04-08 |
2022-05-24 |
X4 Pharmaceuticals, Inc. |
Methods for treating cancer
|
|
EP3443001B1
(en)
|
2016-04-11 |
2025-04-30 |
Obsidian Therapeutics, Inc. |
REGULATED BIOCIRCUIT SYSTEMS
|
|
CN106399255B
(zh)
*
|
2016-04-13 |
2019-10-18 |
阿思科力(苏州)生物科技有限公司 |
Pd-1 car-t细胞及其制备方法和应用
|
|
US10188749B2
(en)
|
2016-04-14 |
2019-01-29 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
IL262365B2
(en)
|
2016-04-15 |
2024-11-01 |
Alpine Immune Sciences Inc |
Immunomodulatory proteins ICOS ligand variants and uses thereof
|
|
EP4706777A2
(en)
|
2016-04-15 |
2026-03-11 |
Alpine Immune Sciences, Inc. |
Cd80 variant immunomodulatory proteins and uses thereof
|
|
MY209117A
(en)
|
2016-04-15 |
2025-06-23 |
Novartis Ag |
Compositions and methods for selective protein expression
|
|
EP3446119A1
(en)
|
2016-04-18 |
2019-02-27 |
The Broad Institute Inc. |
Improved hla epitope prediction
|
|
CN105907719B
(zh)
*
|
2016-04-18 |
2019-10-18 |
阿思科力(苏州)生物科技有限公司 |
Anti ROBO1 CAR-T细胞及其制备和应用
|
|
CN109414512A
(zh)
|
2016-04-22 |
2019-03-01 |
科济生物医药(上海)有限公司 |
用于细胞免疫疗法的组合物和方法
|
|
WO2017192536A1
(en)
|
2016-05-02 |
2017-11-09 |
University Of Kansas |
Eliminating mhc restriction from the t cell receptor as a strategy for immunotherapy
|
|
CN116850305A
(zh)
|
2016-05-06 |
2023-10-10 |
朱诺治疗学股份有限公司 |
基因工程化细胞及其制备方法
|
|
US11261223B2
(en)
*
|
2016-05-11 |
2022-03-01 |
The University Of Chicago |
Methods of treating cancers with CT45 targeted therapies
|
|
AU2017268842B2
(en)
|
2016-05-27 |
2022-08-11 |
Aadigen, Llc |
Peptides and nanoparticles for intracellular delivery of genome-editing molecules
|
|
AU2017271606B2
(en)
*
|
2016-05-27 |
2024-08-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
FLT3-specific chimeric antigen receptors and methods using same
|
|
CN105837693A
(zh)
*
|
2016-05-30 |
2016-08-10 |
李斯文 |
一种基于bcma的抗原嵌合受体及其制备方法和应用
|
|
US20210177896A1
(en)
|
2016-06-02 |
2021-06-17 |
Novartis Ag |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
MX2018014991A
(es)
|
2016-06-03 |
2019-08-29 |
Memorial Sloan Kettering Cancer Center |
Terapias adoptivas de celulas como opciones de tratamiento temprano.
|
|
GB201609811D0
(en)
|
2016-06-05 |
2016-07-20 |
Snipr Technologies Ltd |
Methods, cells, systems, arrays, RNA and kits
|
|
MA45341A
(fr)
|
2016-06-06 |
2019-04-10 |
Hutchinson Fred Cancer Res |
Procédés de traitement de malignités de lymphocytes b au moyen d'une thérapie cellulaire adoptive
|
|
US11390658B2
(en)
|
2016-06-06 |
2022-07-19 |
St. Jude Children's Research Hospital |
Anti-CD7 chimeric antigen receptor and method of use thereof
|
|
EP3458479B1
(en)
|
2016-06-08 |
2020-11-04 |
AbbVie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
|
SG11201810640RA
(en)
|
2016-06-08 |
2018-12-28 |
Intrexon Corp |
Cd33 specific chimeric antigen receptors
|
|
JP2019526529A
(ja)
|
2016-06-08 |
2019-09-19 |
アッヴィ・インコーポレイテッド |
抗b7−h3抗体及び抗体薬物コンジュゲート
|
|
EP3469000A1
(en)
|
2016-06-08 |
2019-04-17 |
AbbVie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
|
BR112018075630A2
(pt)
|
2016-06-08 |
2019-03-19 |
Abbvie Inc. |
anticorpos anti-cd98 e conjugados de fármaco de anticorpo
|
|
CN116173232A
(zh)
|
2016-06-08 |
2023-05-30 |
艾伯维公司 |
抗cd98抗体及抗体药物偶联物
|
|
BR112018075644A2
(pt)
|
2016-06-08 |
2019-04-09 |
Abbvie Inc. |
anticorpos anti-cd98 e conjugados de anticorpo e fármaco
|
|
CN107523545A
(zh)
*
|
2016-06-20 |
2017-12-29 |
上海细胞治疗研究院 |
一种高效稳定表达抗体的杀伤性细胞及其用途
|
|
ES2870920T3
(es)
|
2016-06-21 |
2021-10-28 |
X4 Pharmaceuticals Inc |
Inhibidores de CXCR4 y usos de los mismos
|
|
CN109640988A
(zh)
|
2016-06-21 |
2019-04-16 |
X4 制药有限公司 |
Cxcr4抑制剂及其用途
|
|
WO2017223243A1
(en)
|
2016-06-21 |
2017-12-28 |
X4 Pharmaceuticals, Inc. |
Cxcr4 inhibitors and uses thereof
|
|
CN106117367B
(zh)
*
|
2016-06-24 |
2020-02-11 |
安徽未名细胞治疗有限公司 |
一种her-3特异性嵌合抗原受体及其应用
|
|
JP7114490B2
(ja)
|
2016-06-24 |
2022-08-08 |
アイセル・ジーン・セラピューティクス・エルエルシー |
キメラ抗体受容体(CARs)の構成およびその使用方法
|
|
MA45491A
(fr)
|
2016-06-27 |
2019-05-01 |
Juno Therapeutics Inc |
Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés
|
|
WO2018005559A1
(en)
|
2016-06-27 |
2018-01-04 |
Juno Therapeutics, Inc. |
Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
|
|
CN109476749A
(zh)
|
2016-06-30 |
2019-03-15 |
豪夫迈·罗氏有限公司 |
改良的过继性t细胞疗法
|
|
TWI691510B
(zh)
|
2016-07-12 |
2020-04-21 |
美商凱特製藥公司 |
抗原結合分子和使用彼之方法
|
|
JP2018035137A
(ja)
|
2016-07-13 |
2018-03-08 |
マブイミューン ダイアグノスティックス エイジーMabimmune Diagnostics Ag |
新規な抗線維芽細胞活性化タンパク質(fap)結合薬剤およびその使用
|
|
GB2567093A
(en)
|
2016-07-15 |
2019-04-03 |
Viracta Therapeutics Inc |
Histone deacetylase inhibitors for use in immunotherapy
|
|
US20190336504A1
(en)
|
2016-07-15 |
2019-11-07 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
|
AU2017299854A1
(en)
*
|
2016-07-18 |
2019-01-31 |
Helix Biopharma Corp. |
CAR immune cells directed to carcinoembryonic antigen related cell adhesion molecule 6 to treat cancer
|
|
EP3487878A4
(en)
|
2016-07-20 |
2020-03-25 |
University of Utah Research Foundation |
CD229-CAR-T CELLS AND METHOD FOR USE THEREOF
|
|
US11384156B2
(en)
|
2016-07-25 |
2022-07-12 |
The Nemours Foundation |
Adoptive T-cell therapy using EMPD-specific chimeric antigen receptors for treating IgE-mediated allergic diseases
|
|
US11471488B2
(en)
|
2016-07-28 |
2022-10-18 |
Alpine Immune Sciences, Inc. |
CD155 variant immunomodulatory proteins and uses thereof
|
|
CN110088127A
(zh)
|
2016-07-28 |
2019-08-02 |
高山免疫科学股份有限公司 |
Cd155变体免疫调节蛋白及其用途
|
|
US11834490B2
(en)
|
2016-07-28 |
2023-12-05 |
Alpine Immune Sciences, Inc. |
CD112 variant immunomodulatory proteins and uses thereof
|
|
BR112019001570A2
(pt)
|
2016-07-28 |
2019-07-09 |
Novartis Ag |
terapias de combinação de receptores de antígeno quiméricos e inibidores de pd-1
|
|
US20240018268A1
(en)
|
2016-07-29 |
2024-01-18 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies against anti-cd19 antibodies
|
|
JP7483373B2
(ja)
|
2016-07-29 |
2024-05-15 |
ジュノー セラピューティクス インコーポレイテッド |
複製可能ウイルスの存在または非存在を評価するための方法
|
|
MA45779A
(fr)
|
2016-07-29 |
2019-06-05 |
Juno Therapeutics Inc |
Polypeptides immunomdulateurs et compositions et procédés associés
|
|
US20190161542A1
(en)
|
2016-08-01 |
2019-05-30 |
Novartis Ag |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
|
EP3494138A1
(en)
|
2016-08-02 |
2019-06-12 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
US11078481B1
(en)
|
2016-08-03 |
2021-08-03 |
KSQ Therapeutics, Inc. |
Methods for screening for cancer targets
|
|
US11630103B2
(en)
|
2016-08-17 |
2023-04-18 |
The Broad Institute, Inc. |
Product and methods useful for modulating and evaluating immune responses
|
|
EP4342978A3
(en)
|
2016-09-01 |
2024-07-03 |
Chimera Bioengineering Inc. |
Gold optimized car t-cells
|
|
EP4282969A3
(en)
|
2016-09-02 |
2024-01-31 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with duocars
|
|
US11078483B1
(en)
|
2016-09-02 |
2021-08-03 |
KSQ Therapeutics, Inc. |
Methods for measuring and improving CRISPR reagent function
|
|
JP2019530440A
(ja)
|
2016-09-02 |
2019-10-24 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
インターロイキン6受容体α結合単鎖可変断片を含む方法および組成物
|
|
US20190262399A1
(en)
|
2016-09-07 |
2019-08-29 |
The Broad Institute, Inc. |
Compositions and methods for evaluating and modulating immune responses
|
|
BR112019004662A2
(pt)
|
2016-09-12 |
2019-05-28 |
Juno Therapeutics Inc |
conjuntos de sacos de biorreator de perfusão
|
|
CA3037518A1
(en)
|
2016-09-21 |
2018-03-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptor (car) that targets chemokine receptor ccr4 and its use
|
|
JP2020501512A
(ja)
*
|
2016-09-23 |
2020-01-23 |
ユニバーシティ オブ サザン カリフォルニア |
キメラ抗原受容体およびその組成物ならびにそれらの使用の方法
|
|
WO2018064208A1
(en)
|
2016-09-28 |
2018-04-05 |
The Broad Institute, Inc. |
Systematic screening and mapping of regulatory elements in non-coding genomic regions, methods, compositions, and applications thereof
|
|
ES3013602T3
(en)
|
2016-09-28 |
2025-04-14 |
Kite Pharma Inc |
Antigen binding molecules and methods of use thereof
|
|
EP4353319A3
(en)
|
2016-09-28 |
2024-06-05 |
Atossa Therapeutics, Inc. |
Methods of adoptive cell therapy
|
|
CN110139873A
(zh)
|
2016-10-03 |
2019-08-16 |
朱诺治疗学股份有限公司 |
Hpv特异性结合分子
|
|
CA3036745A1
(en)
|
2016-10-07 |
2018-04-12 |
TCR2 Therapeutics Inc. |
Compositions and methods for t-cell receptors reprogramming using fusion proteins
|
|
EP3523331A1
(en)
|
2016-10-07 |
2019-08-14 |
Novartis AG |
Chimeric antigen receptors for the treatment of cancer
|
|
US12447213B2
(en)
|
2016-10-07 |
2025-10-21 |
The Broad Institute, Inc. |
Modulation of novel immune checkpoint targets
|
|
CN107151654B
(zh)
*
|
2016-10-11 |
2020-05-05 |
深圳宾德生物技术有限公司 |
一种人源t淋巴细胞的培养基及其制备方法和应用
|
|
CN107936120B
(zh)
*
|
2016-10-13 |
2021-03-09 |
上海赛比曼生物科技有限公司 |
Cd19靶向性的嵌合抗原受体及其制法和应用
|
|
BR112019006652A2
(pt)
|
2016-10-13 |
2019-07-02 |
Juno Therapeutics Inc |
métodos e composições para imunoterapia envolvendo moduladores da via metabólica do triptofano
|
|
JP7181862B2
(ja)
|
2016-10-18 |
2022-12-01 |
リージェンツ オブ ザ ユニバーシティ オブ ミネソタ |
腫瘍浸潤リンパ球および治療の方法
|
|
CN110267982B
(zh)
|
2016-10-19 |
2024-02-23 |
斯克利普斯研究所 |
具有人源化靶向部分和/或经过优化的嵌合抗原受体相互作用结构域的嵌合抗原受体效应细胞开关以及其用途
|
|
CA3040296A1
(en)
|
2016-10-20 |
2018-04-26 |
Alpine Immune Sciences, Inc. |
Secretable variant immunomodulatory proteins and engineered cell therapy
|
|
WO2018075820A2
(en)
|
2016-10-20 |
2018-04-26 |
Celgene Corporation |
Cereblon-based heterodimerizable chimeric antigen receptors
|
|
TWI788307B
(zh)
|
2016-10-31 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
|
|
AU2017355544A1
(en)
|
2016-11-03 |
2019-05-16 |
Juno Therapeutics, Inc. |
Combination therapy of a T cell therapy and a BTK inhibitor
|
|
US20190292246A1
(en)
|
2016-11-03 |
2019-09-26 |
Juno Therapeutics, Inc. |
Combination therapy of a cell based therapy and a microglia imhibitor
|
|
KR20240005168A
(ko)
|
2016-11-04 |
2024-01-11 |
2세븐티 바이오, 인코포레이티드 |
항-bcma car t 세포 조성물
|
|
WO2018089386A1
(en)
|
2016-11-11 |
2018-05-17 |
The Broad Institute, Inc. |
Modulation of intestinal epithelial cell differentiation, maintenance and/or function through t cell action
|
|
US11261428B2
(en)
|
2018-03-15 |
2022-03-01 |
KSQ Therapeutics, Inc. |
Gene-regulating compositions and methods for improved immunotherapy
|
|
US11332713B2
(en)
|
2016-11-16 |
2022-05-17 |
KSQ Therapeutics, Inc. |
Gene-regulating compositions and methods for improved immunotherapy
|
|
EP3541847A4
(en)
|
2016-11-17 |
2020-07-08 |
Seattle Genetics, Inc. |
COMPOUNDS INTERACTING WITH GLYCANE AND METHODS OF USE
|
|
SG11201903830TA
(en)
*
|
2016-11-22 |
2019-05-30 |
Nat Univ Singapore |
Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies
|
|
US11851491B2
(en)
|
2016-11-22 |
2023-12-26 |
TCR2 Therapeutics Inc. |
Compositions and methods for TCR reprogramming using fusion proteins
|
|
CN110114070A
(zh)
|
2016-11-23 |
2019-08-09 |
诺华公司 |
使用依维莫司(everolimus)、达托里昔布(dactolisib)或二者增强免疫反应的方法
|
|
AU2017368320A1
(en)
*
|
2016-12-02 |
2019-05-02 |
Cartesian Therapeutics, Inc. |
Cancer immuno therapy with highly enriched CD8+ chimeric antigen receptor T cells
|
|
BR112019011065A2
(pt)
|
2016-12-03 |
2019-10-01 |
Juno Therapeutics Inc |
métodos para determinação da dosagem de células t car
|
|
AU2017368332A1
(en)
|
2016-12-03 |
2019-06-13 |
Juno Therapeutics, Inc. |
Methods for modulation of CAR-T cells
|
|
MA46995A
(fr)
|
2016-12-03 |
2019-10-09 |
Acerta Pharma Bv |
Méthodes et compositions pour l'utilisation de lymphocytes t thérapeutiques en association avec des inhibiteurs de kinase
|
|
AU2017370644A1
(en)
|
2016-12-05 |
2019-06-13 |
Juno Therapeutics, Inc. |
Production of engineered cells for adoptive cell therapy
|
|
CN108165568B
(zh)
*
|
2016-12-07 |
2020-12-08 |
上海恒润达生生物科技有限公司 |
一种培养CD19CAR-iNKT细胞方法及用途
|
|
CN107058315B
(zh)
*
|
2016-12-08 |
2019-11-08 |
上海优卡迪生物医药科技有限公司 |
敲减人PD-1的siRNA、重组表达CAR-T载体及其构建方法和应用
|
|
CN110291200B
(zh)
|
2016-12-12 |
2024-05-14 |
西雅图儿童医院(Dba西雅图儿童研究所) |
对哺乳动物细胞中转基因表达的药剂配体诱导具有增大的灵敏度的嵌合转录因子变异体
|
|
CN108218994A
(zh)
*
|
2016-12-14 |
2018-06-29 |
上海恒润达生生物科技有限公司 |
一种方法培养t记忆干细胞
|
|
AU2017378482B2
(en)
|
2016-12-16 |
2024-06-13 |
R&D Systems, Inc. |
Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
|
|
US11278570B2
(en)
|
2016-12-16 |
2022-03-22 |
B-Mogen Biotechnologies, Inc. |
Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
|
|
CN108276493B
(zh)
*
|
2016-12-30 |
2023-11-14 |
南京传奇生物科技有限公司 |
一种嵌合抗原受体及其应用
|
|
WO2018119518A1
(en)
|
2017-01-01 |
2018-07-05 |
Lee Chi Yu Gregory |
Rp215 chimeric antigen receptor construct and methods of making and using same
|
|
JP7348063B2
(ja)
|
2017-01-05 |
2023-09-20 |
フレッド ハッチンソン キャンサー センター |
ワクチン効力を改善するためのシステム及び方法
|
|
EP3565638B8
(en)
|
2017-01-06 |
2024-04-10 |
BicycleRD Limited |
Bicycle conjugate for treating cancer
|
|
CA3049165A1
(en)
|
2017-01-06 |
2018-07-12 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof
|
|
BR112019013940A2
(pt)
|
2017-01-06 |
2020-02-11 |
Iovance Biotherapeutics, Inc. |
Método de tratar um câncer com uma população de linfócitos infiltrantes de tumor, processo para preparação de uma população de linfócitos infiltrantes de tumor, população de linfócitos infiltrantes de tumor, e, composição farmacêutica.
|
|
EP3346001A1
(en)
*
|
2017-01-06 |
2018-07-11 |
TXCell |
Monospecific regulatory t cell population with cytotoxicity for b cells
|
|
CN108285920A
(zh)
*
|
2017-01-09 |
2018-07-17 |
上海恒润达生生物科技有限公司 |
一种体内检测cart细胞表达的技术及其用途
|
|
MX2019008227A
(es)
|
2017-01-10 |
2020-08-17 |
Juno Therapeutics Inc |
Analisis epigenetico de terapia celular y metodos relacionados.
|
|
GB201700553D0
(en)
|
2017-01-12 |
2017-03-01 |
Genagon Therapeutics Ab |
Therapeutic agents
|
|
WO2018132695A1
(en)
*
|
2017-01-13 |
2018-07-19 |
Celdara Medical, Llc |
Chimeric antigen receptors targeting tim-1
|
|
MX2019008538A
(es)
|
2017-01-20 |
2019-11-05 |
Juno Therapeutics Gmbh |
Conjugados de superficie celular y composiciones y métodos celulares relacionados.
|
|
WO2018140391A1
(en)
|
2017-01-24 |
2018-08-02 |
The Broad Institute, Inc. |
Compositions and methods for detecting a mutant variant of a polynucleotide
|
|
CN108342363B
(zh)
*
|
2017-01-25 |
2021-02-12 |
北京马力喏生物科技有限公司 |
共表达抗msln嵌合抗原受体和免疫检查点抑制分子的转基因淋巴细胞及其用途
|
|
EP4043485A1
(en)
|
2017-01-26 |
2022-08-17 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
RU2674894C2
(ru)
*
|
2017-01-30 |
2018-12-13 |
Общество с ограниченной ответственностью "ПЛАНТА" |
Новые люциферазы и способы их использования
|
|
WO2018144597A1
(en)
*
|
2017-01-31 |
2018-08-09 |
University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Methods of sensitizing cancer cells to immune cell killing
|
|
CN110582509A
(zh)
|
2017-01-31 |
2019-12-17 |
诺华股份有限公司 |
使用具有多特异性的嵌合t细胞受体蛋白治疗癌症
|
|
CN110612119B
(zh)
|
2017-02-07 |
2024-10-29 |
西雅图儿童医院(Dba西雅图儿童研究所) |
磷脂醚(ple)car t细胞肿瘤靶向(ctct)剂
|
|
CN108395482B
(zh)
|
2017-02-08 |
2021-02-05 |
西比曼生物科技(香港)有限公司 |
一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定
|
|
WO2018148671A1
(en)
|
2017-02-12 |
2018-08-16 |
Neon Therapeutics, Inc. |
Hla-based methods and compositions and uses thereof
|
|
PT3583129T
(pt)
*
|
2017-02-14 |
2021-12-14 |
Kite Pharma Inc |
Moléculas de ligação a cd70 e seus métodos de uso
|
|
IL268349B2
(en)
|
2017-02-17 |
2024-08-01 |
Hutchinson Fred Cancer Res |
Combination therapies for treatment of bcma-related cancers and autoimmune disorders
|
|
US12163952B2
(en)
|
2017-02-27 |
2024-12-10 |
Juno Therapeutics, Inc. |
Determining toxicity risk in CAR T-cell therapy
|
|
WO2018157072A1
(en)
|
2017-02-27 |
2018-08-30 |
Life Technologies Corporation |
Expansion of populations of t cells by the use of modified serum free media
|
|
JP7178355B2
(ja)
|
2017-02-28 |
2022-11-25 |
エンドサイト・インコーポレイテッド |
Car t細胞療法のための組成物および方法
|
|
EP3589647A1
(en)
|
2017-02-28 |
2020-01-08 |
Novartis AG |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
|
KR102746901B1
(ko)
|
2017-03-03 |
2024-12-26 |
옵시디안 테라퓨틱스, 인크. |
Cd19 조성물 및 면역요법을 위한 방법
|
|
CA3055200A1
(en)
|
2017-03-03 |
2018-09-07 |
Obsidian Therapeutics, Inc. |
Compositions and methods for immunotherapy
|
|
US11629340B2
(en)
|
2017-03-03 |
2023-04-18 |
Obsidian Therapeutics, Inc. |
DHFR tunable protein regulation
|
|
KR102653141B1
(ko)
|
2017-03-03 |
2024-04-01 |
씨젠 인크. |
글리칸-상호작용 화합물 및 사용 방법
|
|
WO2018169922A2
(en)
|
2017-03-13 |
2018-09-20 |
Kite Pharma, Inc. |
Chimeric antigen receptors for melanoma and uses thereof
|
|
SG11201908271WA
(en)
|
2017-03-14 |
2019-10-30 |
Juno Therapeutics Inc |
Methods for cryogenic storage
|
|
PT3596116T
(pt)
|
2017-03-16 |
2023-12-04 |
Alpine Immune Sciences Inc |
Proteínas imunomoduladoras de pd-l1 variante e suas utilizações
|
|
EP3596114A2
(en)
|
2017-03-16 |
2020-01-22 |
Alpine Immune Sciences, Inc. |
Cd80 variant immunomodulatory proteins and uses thereof
|
|
JP2020511144A
(ja)
|
2017-03-16 |
2020-04-16 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
Pd−l2バリアント免疫調節タンパク質及びその使用
|
|
AU2018236461B2
(en)
|
2017-03-17 |
2025-03-27 |
Fred Hutchinson Cancer Center |
Immunomodulatory fusion proteins and uses thereof
|
|
WO2018175636A2
(en)
|
2017-03-22 |
2018-09-27 |
Novartis Ag |
Compositions and methods for immunooncology
|
|
JP2020515542A
(ja)
|
2017-03-23 |
2020-05-28 |
ザ ジェネラル ホスピタル コーポレイション |
Cxcr4/cxcr7の遮断およびヒトパピローマウイルス関連疾患の治療
|
|
JP7137896B2
(ja)
*
|
2017-03-24 |
2022-09-15 |
レンティジェン・テクノロジー・インコーポレイテッド |
抗cd33免疫療法によりがんを処置するための組成物および方法
|
|
MX2019011570A
(es)
|
2017-03-27 |
2019-11-18 |
Nat Univ Singapore |
Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
|
|
KR102660336B1
(ko)
|
2017-03-27 |
2024-04-26 |
내셔널 유니버시티 오브 싱가포르 |
절단된 nkg2d 키메라 수용체 및 자연 살해 세포 면역요법에서의 그의 용도
|
|
WO2018183888A2
(en)
|
2017-03-31 |
2018-10-04 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling
|
|
WO2018183908A1
(en)
|
2017-03-31 |
2018-10-04 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating ovarian tumors
|
|
EP3490605B1
(en)
|
2017-04-01 |
2023-06-07 |
AVM Biotechnology, LLC |
Replacement of cytotoxic preconditioning before cellular immunotherapy
|
|
EP3606518A4
(en)
|
2017-04-01 |
2021-04-07 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR DETECTION AND MODULATION OF IMMUNOTHERAPY RESISTANCE GENE SIGNATURE IN CANCER
|
|
US12303561B2
(en)
|
2017-04-03 |
2025-05-20 |
Biontech Us Inc. |
Protein antigens and uses thereof
|
|
AU2018250148B2
(en)
|
2017-04-03 |
2021-09-23 |
Kite Pharma, Inc. |
Treatment using chimeric receptor T cells incorporating optimized polyfunctional T cells
|
|
EP3607319A1
(en)
|
2017-04-07 |
2020-02-12 |
Juno Therapeutics, Inc. |
Engineered cells expressing prostate-specific membrane antigen (psma) or a modified form thereof and related methods
|
|
WO2018191558A1
(en)
|
2017-04-12 |
2018-10-18 |
The Broad Institute, Inc. |
Modulation of epithelial cell differentiation, maintenance and/or function through t cell action, and markers and methods of use thereof
|
|
US20200071773A1
(en)
|
2017-04-12 |
2020-03-05 |
Massachusetts Eye And Ear Infirmary |
Tumor signature for metastasis, compositions of matter methods of use thereof
|
|
CN110709700A
(zh)
|
2017-04-14 |
2020-01-17 |
朱诺治疗学股份有限公司 |
评估细胞表面糖基化的方法
|
|
US11753434B2
(en)
|
2017-04-14 |
2023-09-12 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for transient gene therapy with enhanced stability
|
|
CN108727497A
(zh)
*
|
2017-04-17 |
2018-11-02 |
沈阳美达博生物科技有限公司 |
一种cd19抗体及其应用
|
|
WO2018195175A1
(en)
|
2017-04-18 |
2018-10-25 |
FUJIFILM Cellular Dynamics, Inc. |
Antigen-specific immune effector cells
|
|
US20210293783A1
(en)
|
2017-04-18 |
2021-09-23 |
The General Hospital Corporation |
Compositions for detecting secretion and methods of use
|
|
WO2018195339A1
(en)
|
2017-04-19 |
2018-10-25 |
Board Of Regents, The University Of Texas System |
Immune cells expressing engineered antigen receptors
|
|
BR102018007822A2
(pt)
|
2017-04-20 |
2018-11-06 |
Gilead Sciences, Inc. |
composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição
|
|
WO2018195397A2
(en)
|
2017-04-21 |
2018-10-25 |
Kyn Therapeutics |
Indole ahr inhibitors and uses thereof
|
|
SG10201912400VA
(en)
|
2017-04-24 |
2020-02-27 |
Kite Pharma Inc |
Humanized antigen-binding domains against cd19 and methods of use
|
|
JP7339160B2
(ja)
|
2017-04-27 |
2023-09-05 |
ジュノ セラピューティクス ゲーエムベーハー |
オリゴマー粒子試薬およびその使用方法
|
|
WO2018201056A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
US20200078404A1
(en)
|
2017-05-01 |
2020-03-12 |
Juno Therapeutics, Inc. |
Combination of a cell therapy and an immunomodulatory compound
|
|
CN107226867B
(zh)
*
|
2017-07-25 |
2018-02-06 |
重庆精准生物技术有限公司 |
抗人cd19抗原的嵌合抗原受体及其应用
|
|
WO2018201794A1
(zh)
*
|
2017-05-02 |
2018-11-08 |
重庆精准生物技术有限公司 |
抗人cd19抗原的嵌合抗原受体及其应用
|
|
US20200224161A1
(en)
*
|
2017-05-10 |
2020-07-16 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
|
EP3622092A4
(en)
|
2017-05-11 |
2021-06-23 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS OF USE OF CD8 + TUMOR-INFILTRATING LYMPHOCYTE SUBTYPES AND GENE SIGNATURES THEREOF
|
|
US11166985B2
(en)
|
2017-05-12 |
2021-11-09 |
Crispr Therapeutics Ag |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
|
MX2019013514A
(es)
|
2017-05-12 |
2020-01-20 |
Crispr Therapeutics Ag |
Materiales y metodos para modificar celulas por ingenieria genetica y usos de los mismos en inmunooncologia.
|
|
AU2018269194B2
(en)
|
2017-05-15 |
2025-05-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Bicistronic chimeric antigen receptors and their uses
|
|
US10415017B2
(en)
|
2017-05-17 |
2019-09-17 |
Thunder Biotech, Inc. |
Transgenic macrophages, chimeric antigen receptors, and associated methods
|
|
EP3625342B1
(en)
|
2017-05-18 |
2022-08-24 |
The Broad Institute, Inc. |
Systems, methods, and compositions for targeted nucleic acid editing
|
|
EP3406733A1
(en)
|
2017-05-24 |
2018-11-28 |
SIB Swiss Institute of Bioinformatics |
Kinase mutants and uses thereof
|
|
BR112019024719A2
(pt)
|
2017-05-24 |
2020-06-16 |
Effector Therapeutics, Inc. |
Composições e métodos para resposta imunológica antitumor aprimorada
|
|
JP7187486B2
(ja)
|
2017-05-25 |
2022-12-12 |
レイドス, インコーポレイテッド |
Pd-1およびctla-4二重インヒビターペプチド
|
|
TWI862477B
(zh)
|
2017-05-26 |
2024-11-21 |
美商凱特製藥公司 |
製備和使用胚胎間充質先驅細胞的方法
|
|
CA3065126A1
(en)
|
2017-06-01 |
2018-12-06 |
Innovative Cellular Therapeutics CO., LTD. |
Chimeric antigen receptor cell preparation and uses thereof
|
|
CN111201438A
(zh)
|
2017-06-02 |
2020-05-26 |
朱诺治疗学股份有限公司 |
与和细胞疗法相关的毒性有关的制品和方法
|
|
AU2018275894B2
(en)
|
2017-06-02 |
2025-04-24 |
Juno Therapeutics, Inc. |
Articles of manufacture and methods for treatment using adoptive cell therapy
|
|
WO2018222898A1
(en)
*
|
2017-06-02 |
2018-12-06 |
Mayo Foundation For Medical Education And Research |
System and method for providing clinical outcomes driven expertise for disease treatment
|
|
US12384830B2
(en)
|
2017-06-02 |
2025-08-12 |
Regents Of The University Of Minnesota |
Compositions and methods for improving immunotherapy
|
|
KR20200015717A
(ko)
|
2017-06-09 |
2020-02-12 |
프로비던스 헬스 앤드 서비시즈 - 오레곤 |
암 치료를 위한 인간 종양 반응성 t 세포의 확인을 위한 cd39 및 cd103의 활용
|
|
WO2018232195A1
(en)
|
2017-06-14 |
2018-12-20 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
HRP20210567T1
(hr)
|
2017-06-20 |
2021-09-03 |
Institut Curie |
Imune stanice kojima nedostaje suv39hl
|
|
AU2018289428B2
(en)
|
2017-06-21 |
2024-06-27 |
The General Hospital Corporation |
Methods and compositions for chimeric antigen receptor targeting cancer cells
|
|
CA3287539A1
(en)
|
2017-06-21 |
2026-03-02 |
Icell Gene Therapeutics Llc |
CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOF
|
|
CN118307674A
(zh)
|
2017-06-22 |
2024-07-09 |
诺华股份有限公司 |
针对cd73的抗体分子及其用途
|
|
WO2018237173A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
CA3068286A1
(en)
|
2017-06-22 |
2018-12-27 |
Board Of Regents, The University Of Texas System |
Methods for producing regulatory immune cells and uses thereof
|
|
JP7301757B2
(ja)
|
2017-06-26 |
2023-07-03 |
バイスクルアールディー・リミテッド |
検出可能部分を持つ二環式ペプチドリガンドおよびその使用
|
|
SG11201912240QA
(en)
|
2017-06-28 |
2020-01-30 |
Regeneron Pharma |
Anti-human papillomavirus (hpv) antigen-binding proteins and methods of use thereof
|
|
EP3644721A1
(en)
|
2017-06-29 |
2020-05-06 |
Juno Therapeutics, Inc. |
Mouse model for assessing toxicities associated with immunotherapies
|
|
WO2019006418A2
(en)
|
2017-06-30 |
2019-01-03 |
Intima Bioscience, Inc. |
ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
|
|
US12144825B2
(en)
|
2017-06-30 |
2024-11-19 |
Cellectis |
Cellular immunotherapy for repetitive administration
|
|
US11235004B2
(en)
|
2017-06-30 |
2022-02-01 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Lymphocyte cell lines and uses thereof
|
|
CN107287164A
(zh)
*
|
2017-07-07 |
2017-10-24 |
青岛协和华美医学诊断技术有限公司 |
靶向cd19的嵌合抗原受体t细胞、制备方法及应用
|
|
JP7141725B2
(ja)
|
2017-07-07 |
2022-09-26 |
エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド |
変異cd28共刺激ドメインを有するキメラ抗原受容体
|
|
CN107365798B
(zh)
*
|
2017-07-13 |
2020-07-14 |
山东省齐鲁细胞治疗工程技术有限公司 |
一种携带iCasp9自杀基因的CD19-CAR-T细胞及其应用
|
|
US12049643B2
(en)
|
2017-07-14 |
2024-07-30 |
The Broad Institute, Inc. |
Methods and compositions for modulating cytotoxic lymphocyte activity
|
|
WO2019018402A2
(en)
*
|
2017-07-17 |
2019-01-24 |
Janssen Biotech, Inc. |
ANTIGEN-BINDING REGIONS DIRECTED AGAINST FIBRONECTIN TYPE III DOMAINS AND METHODS OF USING THE SAME
|
|
BR112020001719A2
(pt)
|
2017-07-29 |
2020-07-21 |
Juno Therapeutics Inc |
reagentes para expansão de células que expressam receptores recombinantes
|
|
US10442867B2
(en)
|
2017-07-31 |
2019-10-15 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-CD19/CD20 immunotherapy
|
|
US12485102B2
(en)
|
2017-08-02 |
2025-12-02 |
The Wistar Institute Of Anatomy And Biology |
Methods and compositions for treating cancer
|
|
WO2019028417A1
(en)
|
2017-08-03 |
2019-02-07 |
The Scripps Research Institute |
MODIFICATION OF B-LYMPHOCYTE RECEPTORS IN B-LYMPHOCYTES
|
|
CN111183147B
(zh)
|
2017-08-04 |
2024-07-05 |
拜斯科技术开发有限公司 |
Cd137特异性的双环肽配体
|
|
IL319255A
(en)
|
2017-08-07 |
2025-04-01 |
Univ Johns Hopkins |
Methods and materials for cancer assessment and treatment
|
|
AU2018313950A1
(en)
|
2017-08-09 |
2020-02-13 |
Juno Therapeutics, Inc. |
Methods for producing genetically engineered cell compositions and related compositions
|
|
CN111263641B
(zh)
|
2017-08-09 |
2025-10-31 |
朱诺治疗学股份有限公司 |
用于制备基因工程化细胞的方法和组合物
|
|
US20190038733A1
(en)
|
2017-08-10 |
2019-02-07 |
National University Of Singapore |
T cell receptor-deficient chimeric antigen receptor t-cells and methods of use thereof
|
|
WO2019036657A1
(en)
|
2017-08-17 |
2019-02-21 |
Kyn Therapeutics |
AHR INHIBITORS AND USES THEREOF
|
|
WO2019046832A1
(en)
|
2017-09-01 |
2019-03-07 |
Juno Therapeutics, Inc. |
GENE EXPRESSION AND EVALUATION OF RISK OF DEVELOPMENT OF TOXICITY FOLLOWING CELL THERAPY
|
|
EP3675876A4
(en)
|
2017-09-01 |
2021-06-02 |
GPB Scientific, Inc. |
METHOD FOR PRODUCING THERAPEUTICALLY ACTIVE CELLS USING MICROFLUIDICS
|
|
EP3679370A1
(en)
|
2017-09-07 |
2020-07-15 |
Juno Therapeutics, Inc. |
Methods of identifying cellular attributes related to outcomes associated with cell therapy
|
|
CN107557337B
(zh)
*
|
2017-09-15 |
2020-06-26 |
山东兴瑞生物科技有限公司 |
一种抗ror1安全型嵌合抗原受体修饰的免疫细胞及其应用
|
|
KR20230052312A
(ko)
|
2017-09-15 |
2023-04-19 |
카이트 파마 인코포레이티드 |
관리 연속성 및 신원 연속성 생물학적 샘플 추적으로 환자-특이적 면역요법 절차를 수행하기 위한 방법 및 시스템
|
|
JP2020533986A
(ja)
|
2017-09-15 |
2020-11-26 |
ライフ テクノロジーズ コーポレーション |
細胞を培養および増殖させるための組成物および方法
|
|
WO2019060425A1
(en)
|
2017-09-19 |
2019-03-28 |
Massachusetts Institute Of Technology |
COMPOSITIONS FOR CHIMERIC ANTIGENIC RECEPTOR T CELL THERAPY AND USES THEREOF
|
|
CA3076261A1
(en)
|
2017-09-19 |
2019-03-28 |
Admare Vintageco1 Investments Ltd. |
Anti-hla-a2 antibodies and methods of using the same
|
|
CN109517820B
(zh)
|
2017-09-20 |
2021-09-24 |
北京宇繁生物科技有限公司 |
一种靶向HPK1的gRNA以及HPK1基因编辑方法
|
|
EP3684822A4
(en)
|
2017-09-20 |
2021-06-16 |
The University of British Columbia |
NEW ANTI-HLA-A2 ANTIBODIES AND USES THEREOF
|
|
JP2020535802A
(ja)
|
2017-09-21 |
2020-12-10 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
標的化核酸編集のための系、方法、及び組成物
|
|
WO2019060693A1
(en)
|
2017-09-22 |
2019-03-28 |
Kymera Therapeutics, Inc. |
CRBN LIGANDS AND USES THEREOF
|
|
CA3076099A1
(en)
|
2017-09-22 |
2019-03-28 |
Kite Pharma, Inc. |
Linkers for chimeric antigen receptors
|
|
MX2020003190A
(es)
|
2017-09-22 |
2020-11-11 |
Kymera Therapeutics Inc |
Degradadores de proteinas y usos de los mismos.
|
|
US10844371B2
(en)
|
2017-09-22 |
2020-11-24 |
Kite Pharma, Inc. |
Antigen binding molecules and methods of use thereof
|
|
WO2019067504A1
(en)
*
|
2017-09-26 |
2019-04-04 |
Longwood University |
SPECIFIC CHIMERIC ANTIGEN RECEPTOR AT PD-1 AS IMMUNOTHERAPY
|
|
CN109554349B
(zh)
*
|
2017-09-27 |
2022-06-24 |
亘喜生物科技(上海)有限公司 |
Pd-1基因表达沉默的工程化免疫细胞
|
|
TWI731268B
(zh)
*
|
2017-09-29 |
2021-06-21 |
財團法人國家衛生研究院 |
可增強抗腫瘤與抗病毒t細胞存活與其功能性之方法與組合物
|
|
EP3695408B1
(en)
|
2017-10-02 |
2026-01-21 |
The Broad Institute, Inc. |
Medical use of cdk4/6- and checkpoint-inhibitors in phased combination, in treatment of cancer
|
|
BR112020006643A2
(pt)
|
2017-10-03 |
2020-09-24 |
Juno Therapeutics Inc |
moléculas de ligação específica ao hpv
|
|
WO2019074892A1
(en)
|
2017-10-09 |
2019-04-18 |
Wisconsin Alumni Research Foundation |
ANTIBODIES TARGETING GLIOBLASTOME STRAIN TYPE CELLS AND METHODS OF USE
|
|
KR102813968B1
(ko)
|
2017-10-10 |
2025-05-29 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
Ctla-4 변이체 면역조절 단백질 및 이의 용도
|
|
CN119930795A
(zh)
|
2017-10-12 |
2025-05-06 |
得克萨斯大学体系董事会 |
用于免疫疗法的t细胞受体
|
|
CA3084470A1
(en)
|
2017-10-18 |
2019-04-25 |
Kite Pharma, Inc. |
Methods of administering chimeric antigen receptor immunotherapy
|
|
JP7585034B2
(ja)
|
2017-10-18 |
2024-11-18 |
ノバルティス アーゲー |
選択的タンパク質分解のための組成物及び方法
|
|
SMT202600062T1
(it)
|
2017-10-18 |
2026-03-09 |
Alpine Immune Sciences Inc |
Proteine immunomodulatrici del ligando di icos variante e composizioni e metodi correlati
|
|
CN109694854B
(zh)
*
|
2017-10-20 |
2023-11-21 |
亘喜生物科技(上海)有限公司 |
通用型嵌合抗原受体t细胞制备技术
|
|
WO2019084055A1
(en)
|
2017-10-23 |
2019-05-02 |
Massachusetts Institute Of Technology |
CLASSIFICATION OF GENETIC VARIATION FROM UNICELLULAR TRANSCRIPTOMS
|
|
US12053490B2
(en)
|
2017-10-26 |
2024-08-06 |
St. Jude Children's Research Hospital, Inc. |
Methods and compositions for treating CD33+ cancers and improving in vivo persistence of chimeric antigen receptor T cells
|
|
EP3700932A1
(en)
|
2017-10-27 |
2020-09-02 |
Kite Pharma, Inc. |
T cell receptor antigen binding molecules and methods of use thereof
|
|
US20210179709A1
(en)
|
2017-10-31 |
2021-06-17 |
Novartis Ag |
Anti-car compositions and methods
|
|
SG11202003657VA
(en)
|
2017-11-01 |
2020-05-28 |
Juno Therapeutics Inc |
Process for producing a t cell composition
|
|
AU2018358067A1
(en)
|
2017-11-01 |
2020-05-07 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for B-cell maturation antigen
|
|
US11851679B2
(en)
|
2017-11-01 |
2023-12-26 |
Juno Therapeutics, Inc. |
Method of assessing activity of recombinant antigen receptors
|
|
WO2019089858A2
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
|
JP7447006B2
(ja)
|
2017-11-01 |
2024-03-11 |
ジュノー セラピューティクス インコーポレイテッド |
B細胞成熟抗原(bcma)に特異的なキメラ抗原受容体
|
|
BR112020008478A2
(pt)
|
2017-11-01 |
2020-10-20 |
Editas Medicine, Inc. |
métodos, composições e componentes para edição de crispr-cas9 de tgfbr2 em células t para imunota-rapia
|
|
EP3704230B1
(en)
|
2017-11-01 |
2024-10-23 |
Juno Therapeutics, Inc. |
Process for generating therapeutic compositions of engineered cells
|
|
US11564946B2
(en)
|
2017-11-01 |
2023-01-31 |
Juno Therapeutics, Inc. |
Methods associated with tumor burden for assessing response to a cell therapy
|
|
AU2018360031B2
(en)
|
2017-11-03 |
2025-08-21 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-ROR1 immunotherapy
|
|
US20200289613A1
(en)
|
2017-11-04 |
2020-09-17 |
Aravive Biologics, Inc. |
Methods of treating metastatic cancers using axl decoy receptors
|
|
SG11202003427XA
(en)
|
2017-11-06 |
2020-05-28 |
Juno Therapeutics Inc |
Combination of a cell therapy and a gamma secretase inhibitor
|
|
JP2021502077A
(ja)
|
2017-11-06 |
2021-01-28 |
エディタス・メディシン,インコーポレイテッド |
免疫療法のためのt細胞におけるcblbのcrispr−cas9編集のための方法、組成物および構成要素
|
|
KR20200085780A
(ko)
|
2017-11-07 |
2020-07-15 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
암의 치료에서 car-t 또는 car-nk 세포를 사용한 lilrb4 표적화
|
|
CN111683962B
(zh)
|
2017-11-10 |
2025-05-16 |
美国政府(由卫生和人类服务部的部长所代表) |
靶向肿瘤抗原的嵌合抗原受体
|
|
JP2021502094A
(ja)
|
2017-11-10 |
2021-01-28 |
ジュノー セラピューティクス インコーポレイテッド |
閉鎖系極低温容器
|
|
EP3710039A4
(en)
|
2017-11-13 |
2021-08-04 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER BY TARGETING THE CLEC2D-KLRB1 PATH
|
|
WO2019094955A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for targeting developmental and oncogenic programs in h3k27m gliomas
|
|
AU2018369639C1
(en)
|
2017-11-14 |
2025-04-03 |
Arcellx, Inc. |
D-domain containing polypeptides and uses thereof
|
|
IL274677B2
(en)
|
2017-11-14 |
2025-01-01 |
Arcellx Inc |
Therapies with multifunctional immune system cells
|
|
SG11202004512XA
(en)
|
2017-11-15 |
2020-06-29 |
Novartis Ag |
Bcma-targeting chimeric antigen receptor, cd19-targeting chimeric antigen receptor, and combination therapies
|
|
WO2019099707A1
(en)
|
2017-11-16 |
2019-05-23 |
Kite Pharma, Inc |
Modified chimeric antigen receptors and methods of use
|
|
EP3714041A1
(en)
*
|
2017-11-22 |
2020-09-30 |
Iovance Biotherapeutics, Inc. |
Expansion of peripheral blood lymphocytes (pbls) from peripheral blood
|
|
CN109837244A
(zh)
*
|
2017-11-25 |
2019-06-04 |
深圳宾德生物技术有限公司 |
一种敲除pd1的靶向cd19的嵌合抗原受体t细胞及其制备方法和应用
|
|
BR112020010579A2
(pt)
|
2017-11-30 |
2020-11-10 |
Novartis Ag |
receptor de antígeno quimérico de alvejamento de bcma e usos do mesmo
|
|
US20210198372A1
(en)
|
2017-12-01 |
2021-07-01 |
Juno Therapeutics, Inc. |
Methods for dosing and for modulation of genetically engineered cells
|
|
US12084514B2
(en)
|
2017-12-04 |
2024-09-10 |
The Board Of Regents Of The University Of Oklahoma |
Anti-DCLK1 antibodies and chimeric antigen receptors, and compositions and methods of use thereof
|
|
WO2019113557A1
(en)
|
2017-12-08 |
2019-06-13 |
Juno Therapeutics, Inc. |
Process for producing a composition of engineered t cells
|
|
CA3084446A1
(en)
|
2017-12-08 |
2019-06-13 |
Juno Therapeutics, Inc. |
Phenotypic markers for cell therapy and related methods
|
|
JP7433230B2
(ja)
|
2017-12-08 |
2024-02-19 |
ジュノー セラピューティクス インコーポレイテッド |
細胞を培養するための無血清培地配合物およびその使用の方法
|
|
US11766455B2
(en)
|
2017-12-14 |
2023-09-26 |
Ezy Biotech Llc |
Subject-specific tumor inhibiting cells and the use thereof
|
|
WO2019118937A1
(en)
|
2017-12-15 |
2019-06-20 |
Juno Therapeutics, Inc. |
Anti-cct5 binding molecules and methods of use thereof
|
|
EP3724885A2
(en)
|
2017-12-15 |
2020-10-21 |
Iovance Biotherapeutics, Inc. |
Systems and methods for determining the beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof and beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof
|
|
WO2019117976A1
(en)
|
2017-12-17 |
2019-06-20 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Peptide hydrogels and use thereof
|
|
US11793867B2
(en)
|
2017-12-18 |
2023-10-24 |
Biontech Us Inc. |
Neoantigens and uses thereof
|
|
CN108018312B
(zh)
*
|
2017-12-20 |
2019-09-10 |
上海优卡迪生物医药科技有限公司 |
一种t淋巴细胞白血病的car-t治疗载体及其构建方法和应用
|
|
US10966999B2
(en)
|
2017-12-20 |
2021-04-06 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3′3′ cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
|
CN111511754B
(zh)
|
2017-12-20 |
2023-09-12 |
捷克共和国有机化学与生物化学研究所 |
活化sting转接蛋白的具有膦酸酯键的2’3’环状二核苷酸
|
|
GB201721833D0
(en)
*
|
2017-12-22 |
2018-02-07 |
Cancer Research Tech Ltd |
Fusion proteins
|
|
IL315310A
(en)
|
2017-12-26 |
2024-10-01 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
CN109970864A
(zh)
*
|
2017-12-28 |
2019-07-05 |
上海细胞治疗研究院 |
一种双向激活共刺激分子受体及其用途
|
|
CN109970866B
(zh)
*
|
2017-12-28 |
2022-10-04 |
上海细胞治疗研究院 |
一种cd28双向激活共刺激分子受体及其用途
|
|
CN109971712B
(zh)
*
|
2017-12-28 |
2023-06-20 |
上海细胞治疗研究院 |
特异性靶向cd19抗原且高水平稳定表达pd-1抗体的car-t细胞及用途
|
|
SG11202006148UA
(en)
|
2018-01-03 |
2020-07-29 |
Alpine Immune Sciences Inc |
Multi-domain immunomodulatory proteins and methods of use thereof
|
|
US12491153B2
(en)
|
2018-01-03 |
2025-12-09 |
Qu Biologics Inc. |
Innate targeting of adoptive cellular therapies
|
|
US11994512B2
(en)
|
2018-01-04 |
2024-05-28 |
Massachusetts Institute Of Technology |
Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity
|
|
JP2021509903A
(ja)
*
|
2018-01-05 |
2021-04-08 |
マックスサイト インコーポレーティッド |
癌の長期car処置
|
|
TW201930591A
(zh)
|
2018-01-08 |
2019-08-01 |
瑞士商諾華公司 |
用於與嵌合抗原受體療法併用之免疫增強rna
|
|
US11919937B2
(en)
|
2018-01-09 |
2024-03-05 |
Board Of Regents, The University Of Texas System |
T cell receptors for immunotherapy
|
|
EP3737692A4
(en)
|
2018-01-09 |
2021-09-29 |
Elstar Therapeutics, Inc. |
CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES
|
|
US10561686B2
(en)
|
2018-01-12 |
2020-02-18 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expansion and uses thereof
|
|
CN112088008B
(zh)
*
|
2018-01-11 |
2024-01-02 |
浙江煦顼技术有限公司 |
修饰细胞的扩增及其用途
|
|
WO2019140387A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Crbn ligands and uses thereof
|
|
WO2019140380A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
BR112020014446A2
(pt)
|
2018-01-15 |
2020-12-29 |
Pfizer Inc. |
Métodos para administrar imunoterapia de receptor de antígeno quimérico em combinação com agonista de 4-1bb
|
|
CN111629715A
(zh)
|
2018-01-18 |
2020-09-04 |
弗莱德哈钦森癌症研究中心 |
通过调节细胞活化状态改变体内免疫细胞的炎症状态
|
|
JP7549303B2
(ja)
|
2018-01-22 |
2024-09-11 |
エンドサイト・インコーポレイテッド |
Car t細胞の使用方法
|
|
KR102115236B1
(ko)
*
|
2018-01-29 |
2020-05-27 |
(주)에스엠티바이오 |
췌장 또는 담관계암 치료를 위한 키메라 항원 수용체
|
|
KR20200116481A
(ko)
|
2018-01-29 |
2020-10-12 |
메르크 파텐트 게엠베하 |
Gcn2 억제제 및 이의 용도
|
|
EP3746071A4
(en)
|
2018-01-29 |
2021-09-01 |
Merck Patent GmbH |
GCN2 INHIBITORS AND THEIR USES
|
|
US11535903B2
(en)
|
2018-01-31 |
2022-12-27 |
Juno Therapeutics, Inc. |
Methods and reagents for assessing the presence or absence of replication competent virus
|
|
JP7383620B2
(ja)
|
2018-01-31 |
2023-11-20 |
セルジーン コーポレイション |
養子細胞療法およびチェックポイント阻害剤を使用する併用療法
|
|
EP3746116A1
(en)
|
2018-01-31 |
2020-12-09 |
Novartis AG |
Combination therapy using a chimeric antigen receptor
|
|
WO2019152957A1
(en)
|
2018-02-02 |
2019-08-08 |
Arizona Board Of Regents On Behalf Of Arizona State University |
Dna-chimeric antigen receptor t cells for immunotherapy
|
|
SG11202007426XA
(en)
|
2018-02-06 |
2020-09-29 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors
|
|
AU2019219454A1
(en)
|
2018-02-09 |
2020-08-27 |
National University Of Singapore |
Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
|
|
US20210087511A1
(en)
*
|
2018-02-09 |
2021-03-25 |
Global Life Sciences Solutions Usa Llc |
Bioprocessing methods for cell therapy
|
|
US10889792B2
(en)
|
2018-02-09 |
2021-01-12 |
Global Life Sciences Solutions Usa Llc |
Cell expansion vessel systems and methods
|
|
CN112055744A
(zh)
|
2018-02-09 |
2020-12-08 |
环球生命科技咨询美国有限责任公司 |
用于在生物处理系统中的流体管线管理的装置
|
|
WO2019154313A1
(zh)
|
2018-02-11 |
2019-08-15 |
江苏恒瑞医药股份有限公司 |
一种分离的嵌合抗原受体以及包含其的修饰t细胞及用途
|
|
US10596165B2
(en)
|
2018-02-12 |
2020-03-24 |
resTORbio, Inc. |
Combination therapies
|
|
CN110157677A
(zh)
*
|
2018-02-12 |
2019-08-23 |
深圳宾德生物技术有限公司 |
一种靶向性t淋巴细胞及其制备方法和应用
|
|
TWI707849B
(zh)
|
2018-02-13 |
2020-10-21 |
美商基利科學股份有限公司 |
Pd‐1/pd‐l1抑制劑
|
|
WO2019160956A1
(en)
|
2018-02-13 |
2019-08-22 |
Novartis Ag |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
EP3752531A1
(en)
|
2018-02-14 |
2020-12-23 |
Kite Pharma, Inc. |
Anti-idiotypic antibodies directed to the antigen-binding portion of an bcma-binding molecule
|
|
CN112534044A
(zh)
|
2018-02-16 |
2021-03-19 |
凯德药业股份有限公司 |
经修饰的多能干细胞及制备和使用方法
|
|
CA3091478A1
(en)
|
2018-02-17 |
2019-08-22 |
Flagship Pioneering Innovations V, Inc. |
Compositions and methods for membrane protein delivery
|
|
JP7273421B2
(ja)
|
2018-02-21 |
2023-05-15 |
ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム |
ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用
|
|
CN112105382A
(zh)
|
2018-02-23 |
2020-12-18 |
恩多塞特公司 |
用于car t细胞疗法的顺序方法
|
|
JP2021514953A
(ja)
|
2018-02-23 |
2021-06-17 |
バイスクルテクス・リミテッド |
多量体二環式ペプチドリガンド
|
|
GB201803178D0
(en)
|
2018-02-27 |
2018-04-11 |
Univ Oslo Hf |
Specific binding molecules for htert
|
|
MX2020009272A
(es)
|
2018-03-06 |
2021-01-08 |
Univ Pennsylvania |
Receptores de antígeno quimérico del antígeno de membrana específico de próstata y métodos de uso de los mismos.
|
|
WO2019170845A1
(en)
|
2018-03-09 |
2019-09-12 |
Ospedale San Raffaele S.R.L. |
Il-1 antagonist and toxicity induced by cell therapy
|
|
WO2019175328A1
(en)
|
2018-03-14 |
2019-09-19 |
Imba - Institut Für Molekulare Biotechnologie Gmbh |
Bh4pathwayactivationandusethereoffortreatingcancer
|
|
US20190284553A1
(en)
|
2018-03-15 |
2019-09-19 |
KSQ Therapeutics, Inc. |
Gene-regulating compositions and methods for improved immunotherapy
|
|
DE102018108612A1
(de)
|
2018-03-21 |
2019-09-26 |
Immatics US, Inc. |
Verfahren zur erhöhung der persistenz von adoptiv infundierten t-zellen
|
|
US10760075B2
(en)
|
2018-04-30 |
2020-09-01 |
Snipr Biome Aps |
Treating and preventing microbial infections
|
|
CN112055717B
(zh)
|
2018-04-02 |
2024-04-26 |
新加坡国立大学 |
用在免疫细胞中表达的膜结合抗细胞因子非信号传导粘合剂中和人细胞因子
|
|
AU2019249209A1
(en)
|
2018-04-05 |
2020-10-15 |
Juno Therapeutics, Inc. |
T cell receptors and engineered cells expressing same
|
|
CA3094468A1
(en)
|
2018-04-05 |
2019-10-10 |
Juno Therapeutics, Inc. |
Methods of producing cells expressing a recombinant receptor and related compositions
|
|
TWI833744B
(zh)
|
2018-04-06 |
2024-03-01 |
捷克科學院有機化學與生物化學研究所 |
3'3'-環二核苷酸
|
|
CA3096202A1
(en)
|
2018-04-06 |
2019-10-10 |
The Regents Of The University Of California |
Methods of treating egfrviii expressing glioblastomas
|
|
CA3095757A1
(en)
|
2018-04-06 |
2019-10-10 |
The Regents Of The University Of California |
Methods of treating glioblastomas
|
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
|
TW202005654A
(zh)
|
2018-04-06 |
2020-02-01 |
捷克科學院有機化學與生物化學研究所 |
2,2,─環二核苷酸
|
|
CA3095920A1
(en)
|
2018-04-10 |
2019-10-17 |
Amgen Inc. |
Chimeric receptors to dll3 and methods of use thereof
|
|
TWI784324B
(zh)
|
2018-04-12 |
2022-11-21 |
美商凱特製藥公司 |
利用腫瘤微環境之特性之嵌合受體t細胞治療
|
|
WO2019200252A1
(en)
|
2018-04-13 |
2019-10-17 |
The Johns Hopkins University |
Non-invasive detection of response to immunotherapy
|
|
SG11202010116PA
(en)
|
2018-04-13 |
2020-11-27 |
Sangamo Therapeutics France |
Chimeric antigen receptor specific for interleukin-23 receptor
|
|
WO2019200250A1
(en)
|
2018-04-13 |
2019-10-17 |
Velculescu Victor E |
Non-invasive detection of response to a targeted therapy
|
|
US10973834B2
(en)
|
2018-04-16 |
2021-04-13 |
Arrys Therapeutics, Inc. |
EP4 inhibitors and use thereof
|
|
CA3096549A1
(en)
|
2018-04-16 |
2019-10-24 |
Board Of Regents, The University Of Texas System |
Human kynureninase enzymes and uses thereof
|
|
US10869888B2
(en)
|
2018-04-17 |
2020-12-22 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expansion and uses thereof
|
|
JP7527641B2
(ja)
|
2018-04-18 |
2024-08-05 |
アブクロン・インコーポレイテッド |
スイッチ分子及びスイッチャブルキメラ抗原受容体
|
|
KR102591947B1
(ko)
|
2018-04-19 |
2023-10-25 |
길리애드 사이언시즈, 인코포레이티드 |
Pd-1/pd-l1 억제제
|
|
US20210161958A1
(en)
*
|
2018-04-19 |
2021-06-03 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treating melanoma with a chimeric antigen receptor
|
|
ES2969982T3
(es)
|
2018-04-24 |
2024-05-23 |
Vertex Pharma |
Compuestos de pteridinona y usos de los mismos
|
|
ES2919572T3
(es)
|
2018-04-24 |
2022-07-27 |
Merck Patent Gmbh |
Compuestos antiproliferación y usos de los mismos
|
|
US11957695B2
(en)
|
2018-04-26 |
2024-04-16 |
The Broad Institute, Inc. |
Methods and compositions targeting glucocorticoid signaling for modulating immune responses
|
|
EP3784351A1
(en)
|
2018-04-27 |
2021-03-03 |
Novartis AG |
Car t cell therapies with enhanced efficacy
|
|
JP2021523110A
(ja)
*
|
2018-05-01 |
2021-09-02 |
フレッド ハッチンソン キャンサー リサーチ センター |
遺伝子発現のためのナノ粒子及びその使用
|
|
US20210396739A1
(en)
|
2018-05-01 |
2021-12-23 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
CA3098865A1
(en)
|
2018-05-02 |
2019-11-07 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of phospholipase a2 receptor chimeric autoantibody receptor t cells
|
|
US20210121466A1
(en)
|
2018-05-03 |
2021-04-29 |
Juno Therapeutics, Inc. |
Combination therapy of a chimeric antigen receptor (car) t cell therapy and a kinase inhibitor
|
|
WO2019211799A1
(en)
|
2018-05-03 |
2019-11-07 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide
|
|
CN108753774B
(zh)
*
|
2018-05-03 |
2021-03-30 |
山东省齐鲁细胞治疗工程技术有限公司 |
干扰il-6表达的cd19-car-t细胞及其应用
|
|
EP3790958A1
(en)
|
2018-05-08 |
2021-03-17 |
Life Technologies Corporation |
Compositions and methods for culturing and expanding cells
|
|
US12227763B2
(en)
|
2018-05-11 |
2025-02-18 |
Crispr Therapeutics Ag |
Methods and compositions for treating cancer
|
|
EP3793565B1
(en)
|
2018-05-14 |
2022-01-05 |
Gilead Sciences, Inc. |
Mcl-1 inhibitors
|
|
WO2019222657A1
(en)
|
2018-05-18 |
2019-11-21 |
The Johns Hopkins University |
Cell-free dna for assessing and/or treating cancer
|
|
KR20210008408A
(ko)
|
2018-05-23 |
2021-01-21 |
싱가포르국립대학교 |
T-세포 악성 종양의 면역요법을 위한 cd2 표면 발현 및 키메라 항원 수용체의 발현에 대한 차단
|
|
EP3801769A1
(en)
|
2018-05-25 |
2021-04-14 |
Novartis AG |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
AR126019A1
(es)
|
2018-05-30 |
2023-09-06 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
CN108715859B
(zh)
*
|
2018-05-31 |
2021-08-03 |
中国医学科学院血液病医院(中国医学科学院血液学研究所) |
靶向cd22的嵌合抗原受体及其应用
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
KR102544086B1
(ko)
|
2018-06-01 |
2023-06-16 |
카이트 파마 인코포레이티드 |
키메라 항원 수용체 t 세포 요법
|
|
UY38251A
(es)
|
2018-06-01 |
2019-12-31 |
Novartis Ag |
Moléculas de unión contra bcma y usos de las mismas
|
|
JP7411578B2
(ja)
*
|
2018-06-01 |
2024-01-11 |
マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ |
癌を治療するための物質及び方法
|
|
US20210371932A1
(en)
|
2018-06-01 |
2021-12-02 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
|
WO2019237035A1
(en)
|
2018-06-08 |
2019-12-12 |
Intellia Therapeutics, Inc. |
Compositions and methods for immunooncology
|
|
WO2019241315A1
(en)
|
2018-06-12 |
2019-12-19 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
|
CA3100724A1
(en)
|
2018-06-13 |
2019-12-19 |
Novartis Ag |
B-cell maturation antigen protein (bcma) chimeric antigen receptors and uses thereof
|
|
KR20190141511A
(ko)
*
|
2018-06-14 |
2019-12-24 |
주식회사 녹십자랩셀 |
신규 펩티드, 이를 포함하는 키메라 항원 수용체 및 이를 발현하는 면역 세포
|
|
US12036240B2
(en)
|
2018-06-14 |
2024-07-16 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
US12065476B2
(en)
|
2018-06-15 |
2024-08-20 |
Alpine Immune Sciences, Inc. |
PD-1 variant immunomodulatory proteins and uses thereof
|
|
BR112020025764A2
(pt)
|
2018-06-19 |
2021-05-11 |
Biontech Us Inc. |
neoantígenos e usos dos mesmos
|
|
AU2019288669B2
(en)
|
2018-06-21 |
2025-06-26 |
R&D Systems, Inc. |
Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
|
|
IL279489B2
(en)
|
2018-06-22 |
2025-10-01 |
Bicycletx Ltd |
Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate
|
|
US20210155941A1
(en)
|
2018-06-22 |
2021-05-27 |
Kite Pharma Eu B.V. |
Compositions and methods for making engineered t cells
|
|
EP3818083A2
(en)
|
2018-07-03 |
2021-05-12 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
CA3104862A1
(en)
|
2018-07-03 |
2020-01-09 |
Sotio, LLC |
Chimeric receptors in combination with trans metabolism molecules enhancing glucose import and therapeutic uses thereof
|
|
WO2020010227A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
US11292792B2
(en)
|
2018-07-06 |
2022-04-05 |
Kymera Therapeutics, Inc. |
Tricyclic CRBN ligands and uses thereof
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
EP3820572B1
(en)
|
2018-07-13 |
2023-08-16 |
Gilead Sciences, Inc. |
Pd-1/pd-l1 inhibitors
|
|
JPWO2020017479A1
(ja)
|
2018-07-17 |
2021-08-02 |
ノイルイミューン・バイオテック株式会社 |
抗gpc3一本鎖抗体を含むcar
|
|
EA202190304A1
(ru)
|
2018-07-18 |
2022-01-21 |
Эмджен Инк. |
Химерные рецепторы к steap1 и способы их применения
|
|
MD4324851T2
(ro)
|
2018-07-19 |
2025-12-31 |
Regeneron Pharma |
Receptori antigenici chimerici cu specificitate BCMA și utilizările acestora
|
|
CA3107383A1
(en)
|
2018-07-23 |
2020-01-30 |
Magenta Therapeutics, Inc. |
Use of anti-cd5 antibody drug conjugate (adc) in allogeneic cell therapy
|
|
CN108949759B
(zh)
*
|
2018-07-23 |
2021-06-01 |
合肥一兮生物科技有限公司 |
敲减人IL-15的siRNA、CD19 CAR表达载体、CAR-T细胞及构建方法和应用
|
|
SG11202101014XA
(en)
|
2018-08-02 |
2021-02-25 |
Kite Pharma Inc |
Chimeric antigen receptor therapy t cell expansion kinetics and uses thereof
|
|
CN113474450A
(zh)
|
2018-08-09 |
2021-10-01 |
朱诺治疗学股份有限公司 |
产生工程化细胞的方法以及所述工程化细胞的组合物
|
|
EA202190469A1
(ru)
|
2018-08-09 |
2021-06-28 |
Джуно Терапьютикс, Инк. |
Способы оценки интегрированных нуклеиновых кислот
|
|
EP3835320A4
(en)
*
|
2018-08-10 |
2022-06-01 |
Eutilex Co., Ltd. |
Chimeric antigen receptor binding to hla-dr, and car-t cell
|
|
KR20210045418A
(ko)
|
2018-08-14 |
2021-04-26 |
소티오, 엘엘씨 |
크렙스 사이클을 조정하는 트랜스 대사 분자와 조합된 키메라 항원 수용체 폴리펩타이드 및 이의 치료적 용도
|
|
US20210324357A1
(en)
|
2018-08-20 |
2021-10-21 |
The Brigham And Women's Hospital, Inc. |
Degradation domain modifications for spatio-temporal control of rna-guided nucleases
|
|
US12391685B2
(en)
|
2018-08-20 |
2025-08-19 |
The Broad Institute, Inc. |
Inhibitors of RNA-guided nuclease target binding and uses thereof
|
|
US12460244B2
(en)
|
2018-08-20 |
2025-11-04 |
The Broad Institute, Inc. |
Inhibitors of RNA-guided nuclease activity and uses thereof
|
|
CN110856724B
(zh)
*
|
2018-08-24 |
2022-05-27 |
杭州康万达医药科技有限公司 |
包含核酸及car修饰的免疫细胞的治疗剂及其应用
|
|
BR112021003830A2
(pt)
|
2018-08-28 |
2021-07-20 |
Fred Hutchinson Cancer Research Center |
métodos e composições para terapia celular t adotiva incorporando sinalização notch induzida
|
|
CA3110837A1
(en)
|
2018-08-28 |
2020-03-05 |
Vor Biopharma Inc. |
Genetically engineered hematopoietic stem cells and uses thereof
|
|
EP3844186A4
(en)
|
2018-08-29 |
2022-08-17 |
National University of Singapore |
METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
|
|
JP7156653B2
(ja)
|
2018-08-30 |
2022-10-19 |
イノベイティブ セルラー セラピューティクス ホールディングス,エルティディ |
固形腫瘍を治療するためのキメラ抗原受容体細胞
|
|
US12240915B2
(en)
|
2018-08-30 |
2025-03-04 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Chimeric antigen receptor cells for treating solid tumor
|
|
US10548889B1
(en)
|
2018-08-31 |
2020-02-04 |
X4 Pharmaceuticals, Inc. |
Compositions of CXCR4 inhibitors and methods of preparation and use
|
|
CA3109959A1
(en)
|
2018-08-31 |
2020-03-05 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
WO2020047449A2
(en)
|
2018-08-31 |
2020-03-05 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
US11866494B2
(en)
*
|
2018-08-31 |
2024-01-09 |
Innovative Cellular Therapeutics Holdings, Ltd. |
CAR T therapy through uses of co-stimulation
|
|
US12030875B2
(en)
|
2018-09-07 |
2024-07-09 |
PIC Therapeutics, Inc. |
EIF4E inhibitors and uses thereof
|
|
MX2021002574A
(es)
|
2018-09-11 |
2021-06-08 |
Juno Therapeutics Inc |
Metodos para el analisis por espectrometria de masas de composiciones de celulas modificadas.
|
|
AU2019345151B2
(en)
|
2018-09-19 |
2025-04-17 |
Alpine Immune Sciences, Inc. |
Methods and uses of variant CD80 fusion proteins and related constructs
|
|
EP3856777A1
(en)
|
2018-09-24 |
2021-08-04 |
The Medical College of Wisconsin, Inc. |
Anti-cd30 antibodies and methods of use
|
|
WO2020069409A1
(en)
|
2018-09-28 |
2020-04-02 |
Novartis Ag |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
|
EP3856779A1
(en)
|
2018-09-28 |
2021-08-04 |
Novartis AG |
Cd22 chimeric antigen receptor (car) therapies
|
|
EP3856763A1
(en)
|
2018-09-28 |
2021-08-04 |
Massachusetts Institute of Technology |
Collagen-localized immunomodulatory molecules and methods thereof
|
|
AU2019354391A1
(en)
|
2018-10-01 |
2021-05-06 |
Adicet Therapeutics, Inc. |
Compositions and methods regarding engineered and non- engineered γδ-Τ cells for treatment of hematological tumors
|
|
WO2020072700A1
(en)
|
2018-10-02 |
2020-04-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
|
WO2020072656A1
(en)
|
2018-10-03 |
2020-04-09 |
Gilead Sciences, Inc. |
Imidozopyrimidine derivatives
|
|
EP3488851A1
(en)
|
2018-10-03 |
2019-05-29 |
AVM Biotechnology, LLC |
Immunoablative therapies
|
|
US11851663B2
(en)
|
2018-10-14 |
2023-12-26 |
Snipr Biome Aps |
Single-vector type I vectors
|
|
US20210379057A1
(en)
|
2018-10-16 |
2021-12-09 |
Massachusetts Institute Of Technology |
Nutlin-3a for use in treating a mycobacterium tuberculosis infection
|
|
BR112021007690A2
(pt)
|
2018-10-22 |
2021-08-10 |
Shanghai GenBase Biotechnology Co., Ltd. |
anticorpo anti-cldn18.2 e uso do mesmo
|
|
KR102933479B1
(ko)
|
2018-10-23 |
2026-03-04 |
리제너론 파아마슈티컬스, 인크. |
Ny-eso-1 t 세포 수용체 및 이의 사용 방법
|
|
WO2020086742A1
(en)
|
2018-10-24 |
2020-04-30 |
Obsidian Therapeutics, Inc. |
Er tunable protein regulation
|
|
US11236085B2
(en)
|
2018-10-24 |
2022-02-01 |
Gilead Sciences, Inc. |
PD-1/PD-L1 inhibitors
|
|
EP3870146A4
(en)
*
|
2018-10-25 |
2022-08-10 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Increase or maintaining t-cell subpopulations in adoptive t-cell therapy
|
|
US20220170097A1
(en)
|
2018-10-29 |
2022-06-02 |
The Broad Institute, Inc. |
Car t cell transcriptional atlas
|
|
WO2020092057A1
(en)
|
2018-10-30 |
2020-05-07 |
Yale University |
Compositions and methods for rapid and modular generation of chimeric antigen receptor t cells
|
|
TW202136261A
(zh)
|
2018-10-31 |
2021-10-01 |
美商基利科學股份有限公司 |
經取代之6-氮雜苯并咪唑化合物
|
|
TWI721623B
(zh)
|
2018-10-31 |
2021-03-11 |
美商基利科學股份有限公司 |
經取代之6-氮雜苯并咪唑化合物
|
|
EP3874024A1
(en)
|
2018-10-31 |
2021-09-08 |
Juno Therapeutics GmbH |
Methods for selection and stimulation of cells and apparatus for same
|
|
KR20210113169A
(ko)
|
2018-11-01 |
2021-09-15 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Β세포 성숙 항원에 특이적인 키메라 항원 수용체를 이용한 치료 방법
|
|
SG11202104524YA
(en)
|
2018-11-01 |
2021-05-28 |
Gracell Biotechnologies Shanghai Co Ltd |
Compositions and methods for t cell engineering
|
|
EP3877054B1
(en)
|
2018-11-06 |
2023-11-01 |
Juno Therapeutics, Inc. |
Process for producing genetically engineered t cells
|
|
CN109467604A
(zh)
*
|
2018-11-07 |
2019-03-15 |
南京卡提医学科技有限公司 |
嵌合抗原受体DAP12-T2A-CD8α-CD19scFv-TREM1及其用途
|
|
CA3118889A1
(en)
*
|
2018-11-07 |
2020-05-14 |
Sotio, LLC |
Anti-gpc3 chimeric antigen receptors (cars) in combination with trans co-stimulatory molecules and therapeutic uses thereof
|
|
CN109503717A
(zh)
*
|
2018-11-07 |
2019-03-22 |
南京卡提医学科技有限公司 |
嵌合抗原受体DAP12-T2A-CD8α-CD19scfv-NKp44及其用途
|
|
WO2020097403A1
(en)
|
2018-11-08 |
2020-05-14 |
Juno Therapeutics, Inc. |
Methods and combinations for treatment and t cell modulation
|
|
US12496274B2
(en)
|
2018-11-14 |
2025-12-16 |
Flagship Pioneering Innovations V, Inc. |
Compositions and methods for compartment-specific cargo delivery
|
|
WO2020102503A2
(en)
|
2018-11-14 |
2020-05-22 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions for t cell delivery
|
|
KR20210104713A
(ko)
|
2018-11-16 |
2021-08-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
B 세포 악성 종양 치료를 위한 조작된 t 세포 투약 방법
|
|
EP3883955A1
(en)
|
2018-11-19 |
2021-09-29 |
Board of Regents, The University of Texas System |
A modular, polycistronic vector for car and tcr transduction
|
|
US10918667B2
(en)
|
2018-11-20 |
2021-02-16 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expressing therapeutic agent and uses thereof
|
|
EP3883585A4
(en)
*
|
2018-11-20 |
2022-12-14 |
Innovative Cellular Therapeutics Holdings, Ltd. |
MODIFIED CELL EXPRESSING THERAPEUTIC AND USES THEREOF
|
|
US12590148B2
(en)
|
2018-11-26 |
2026-03-31 |
Nkarta, Inc. |
Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
|
|
WO2020113029A2
(en)
|
2018-11-28 |
2020-06-04 |
Board Of Regents, The University Of Texas System |
Multiplex genome editing of immune cells to enhance functionality and resistance to suppressive environment
|
|
MX2021006393A
(es)
|
2018-11-29 |
2021-10-13 |
Univ Texas |
Metodos para expansion ex vivo de celulas exterminadoras naturales y uso de las mismas.
|
|
PL3886875T3
(pl)
|
2018-11-30 |
2024-09-09 |
Juno Therapeutics, Inc. |
Metody leczenia z wykorzystaniem adoptywnej terapii komórkowej
|
|
WO2020113141A2
(en)
|
2018-11-30 |
2020-06-04 |
Alpine Immune Sciences, Inc. |
Cd86 variant immunomodulatory proteins and uses thereof
|
|
JP7623943B2
(ja)
|
2018-11-30 |
2025-01-29 |
カイメラ セラピューティクス, インコーポレイテッド |
Irak分解剤およびそれらの使用
|
|
PL3886894T3
(pl)
|
2018-11-30 |
2024-07-01 |
Juno Therapeutics, Inc. |
Metody dawkowania i leczenia nowotworów b-komórkowych w adoptywnej terapii komórkowej
|
|
WO2020117952A2
(en)
|
2018-12-05 |
2020-06-11 |
Genentech, Inc. |
Diagnostic methods and compositions for cancer immunotherapy
|
|
CN118931967A
(zh)
*
|
2018-12-07 |
2024-11-12 |
亘喜生物科技(上海)有限公司 |
用于免疫疗法的组合物和方法
|
|
PT3894549T
(pt)
|
2018-12-10 |
2024-10-16 |
Amgen Inc |
Transposase piggybac mutada
|
|
US12227551B2
(en)
|
2018-12-11 |
2025-02-18 |
Obsidian Therapeutics, Inc. |
Membrane bound IL12 compositions and methods for tunable regulation
|
|
KR102840400B1
(ko)
|
2018-12-12 |
2025-08-04 |
카이트 파마 인코포레이티드 |
키메라 항원 수용체 및 car-t 세포 및 사용 방법
|
|
GB201820288D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicycle Tx Ltd |
Bicycle peptide ligaands specific for MT1-MMP
|
|
GB201820295D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for MT1-MMP
|
|
GB201820325D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for psma
|
|
WO2020131586A2
(en)
|
2018-12-17 |
2020-06-25 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
|
EP3670530A1
(en)
|
2018-12-18 |
2020-06-24 |
Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft |
Cd22-specific t cell receptors and adoptive t cell therapy for treatment of b cell malignancies
|
|
EP3670659A1
(en)
|
2018-12-20 |
2020-06-24 |
Abivax |
Biomarkers, and uses in treatment of viral infections, inflammations, or cancer
|
|
KR20210106437A
(ko)
|
2018-12-20 |
2021-08-30 |
노파르티스 아게 |
3-(1-옥소이소인돌린-2-일)피페리딘-2,6-디온 유도체를 포함하는 투약 요법 및 약학적 조합물
|
|
JP2022514618A
(ja)
|
2018-12-21 |
2022-02-14 |
バイスクルテクス・リミテッド |
Pd-l1に特異的な二環式ペプチドリガンド
|
|
US12551567B2
(en)
|
2018-12-21 |
2026-02-17 |
Bicyclerd Limited |
Bicyclic peptide ligands specific for PD-L1
|
|
AU2019404547B2
(en)
|
2018-12-21 |
2025-01-30 |
Biontech Us Inc. |
Method and systems for prediction of HLA class II-specific epitopes and characterization of CD4+ T cells
|
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
|
WO2020142780A1
(en)
*
|
2019-01-06 |
2020-07-09 |
Tocagen Inc. |
Car t cell methods and constructs
|
|
EP3914719A4
(en)
|
2019-01-24 |
2023-04-05 |
Valorisation-HSJ, Limited Partnership |
Cell-specific transcriptional regulatory sequences and uses thereof
|
|
CA3123303A1
(en)
|
2019-01-29 |
2020-08-06 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase like orphan receptor 1 (ror1)
|
|
EP3920693A4
(en)
|
2019-02-04 |
2022-10-05 |
Minerva Biotechnologies Corporation |
ANTI-NME ANTIBODIES AND METHODS OF TREATMENT OF CANCER OR CANCER METASTASIS
|
|
US12419913B2
(en)
|
2019-02-08 |
2025-09-23 |
Dna Twopointo, Inc. |
Modification of CAR-T cells
|
|
EP3924055B1
(en)
|
2019-02-15 |
2024-04-03 |
Novartis AG |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
AU2020221324A1
(en)
|
2019-02-15 |
2021-09-02 |
University Of Southern California |
Lym-1 and Lym-2 antibody compositions and improved CAR constructs
|
|
CN113490528B
(zh)
|
2019-02-15 |
2024-12-03 |
诺华股份有限公司 |
3-(1-氧代-5-(哌啶-4-基)异吲哚啉-2-基)哌啶-2,6-二酮衍生物及其用途
|
|
AU2020224681A1
(en)
|
2019-02-21 |
2021-09-16 |
Marengo Therapeutics, Inc. |
Antibody molecules that bind to NKp30 and uses thereof
|
|
JP7710373B2
(ja)
|
2019-02-21 |
2025-07-18 |
マレンゴ・セラピューティクス,インコーポレーテッド |
T細胞関連のがん細胞に結合する多機能性分子およびその使用
|
|
US20220152150A1
(en)
|
2019-02-25 |
2022-05-19 |
Novartis Ag |
Mesoporous silica particles compositions for viral delivery
|
|
WO2020180591A1
(en)
|
2019-03-01 |
2020-09-10 |
Allogene Therapeutics, Inc. |
Dll3 targeting chimeric antigen receptors and binding agents
|
|
US20220133795A1
(en)
|
2019-03-01 |
2022-05-05 |
Iovance Biotherapeutics, Inc. |
Expansion of Tumor Infiltrating Lymphocytes From Liquid Tumors and Therapeutic Uses Thereof
|
|
MX2021010541A
(es)
|
2019-03-04 |
2021-12-15 |
Univ Health Network |
Receptores de linfocitos t y metodos de uso de estos.
|
|
JP7748284B2
(ja)
|
2019-03-04 |
2025-10-02 |
ユニバーシティー ヘルス ネットワーク |
T細胞受容体及びその使用方法
|
|
AU2020232691B2
(en)
|
2019-03-05 |
2023-06-29 |
Nkarta, Inc. |
CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
|
EP3935066A1
(en)
|
2019-03-07 |
2022-01-12 |
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. |
3'3'-cyclic dinucleotides and prodrugs thereof
|
|
US11766447B2
(en)
|
2019-03-07 |
2023-09-26 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3′3′-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
|
|
KR102707808B1
(ko)
|
2019-03-07 |
2024-09-19 |
인스티튜트 오브 오가닉 케미스트리 앤드 바이오케미스트리 에이에스 씨알 브이.브이.아이. |
2'3'-사이클릭 다이뉴클레오티드 및 이의 프로드럭
|
|
KR20210149251A
(ko)
|
2019-03-08 |
2021-12-08 |
옵시디안 테라퓨틱스, 인크. |
조율가능한 조절을 위한 인간 탄산 무수화효소 2 조성물 및 방법
|
|
WO2020182681A1
(en)
|
2019-03-08 |
2020-09-17 |
Klinikum Der Universität München |
Ccr8 expressing lymphocytes for targeted tumor therapy
|
|
WO2020186101A1
(en)
|
2019-03-12 |
2020-09-17 |
The Broad Institute, Inc. |
Detection means, compositions and methods for modulating synovial sarcoma cells
|
|
US20220142948A1
(en)
|
2019-03-18 |
2022-05-12 |
The Broad Institute, Inc. |
Compositions and methods for modulating metabolic regulators of t cell pathogenicity
|
|
CN120131907A
(zh)
|
2019-03-19 |
2025-06-13 |
瓦尔希伯伦私人肿瘤研究基金会 |
采用Omomyc和结合PD-1或CTLA-4的抗体治疗癌症的联合疗法
|
|
EP3938405A4
(en)
*
|
2019-03-20 |
2022-12-28 |
Javelin Oncology, Inc. |
ANTI-ADAM12 ANTIBODIES AND CHIMERIC ANTIGEN RECEPTORS, AND COMPOSITIONS AND METHODS THEREOF
|
|
EP3942025A1
(en)
|
2019-03-21 |
2022-01-26 |
Novartis AG |
Car-t cell therapies with enhanced efficacy
|
|
CN113795586B
(zh)
|
2019-03-25 |
2026-03-27 |
大学健康网络 |
T细胞受体及其使用方法
|
|
US20220184222A1
(en)
|
2019-04-02 |
2022-06-16 |
Bicycletx Limited |
Bicycle toxin conjugates and uses thereof
|
|
TWI875749B
(zh)
|
2019-04-05 |
2025-03-11 |
美商凱麥拉醫療公司 |
Stat降解劑及其用途
|
|
CN120172958A
(zh)
|
2019-04-12 |
2025-06-20 |
C4医药公司 |
Ikaros和aiolos的三环降解物
|
|
AU2020272074A1
(en)
*
|
2019-04-12 |
2021-11-25 |
The Trustees Of The University Of Pennsylvania |
Compositions and Methods Comprising a High Affinity Chimeric Antigen Receptor (CAR) with Cross-Reactivity to Clinically-Relevant EGFR Mutated Proteins
|
|
WO2020210678A1
(en)
|
2019-04-12 |
2020-10-15 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
TW202212339A
(zh)
|
2019-04-17 |
2022-04-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TW202210480A
(zh)
|
2019-04-17 |
2022-03-16 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
US12404331B2
(en)
|
2019-04-19 |
2025-09-02 |
Tcrcure Biopharma Corp. |
Anti-PD-1 antibodies and uses thereof
|
|
US20220251152A1
(en)
|
2019-04-24 |
2022-08-11 |
Novartis Ag |
Compositions and methods for selective protein degradation
|
|
JP7664180B2
(ja)
|
2019-04-26 |
2025-04-17 |
アロジーン セラピューティクス,インコーポレイテッド |
リツキシマブ耐性キメラ抗原受容体およびその用途
|
|
KR20220004028A
(ko)
|
2019-04-26 |
2022-01-11 |
알로젠 테라퓨틱스 인코포레이티드 |
동종 car t 세포를 제조하는 방법
|
|
US20220249558A1
(en)
|
2019-04-30 |
2022-08-11 |
Crispr Therapeutics Ag |
Allogeneic cell therapy of b cell malignancies using genetically engineered t cells targeting cd19
|
|
EP3962527A4
(en)
|
2019-04-30 |
2023-11-01 |
Senti Biosciences, Inc. |
CHIMERIC RECEPTORS AND METHODS OF USE THEREOF
|
|
AU2020265741A1
(en)
|
2019-05-01 |
2021-11-25 |
Editas Medicine, Inc. |
Cells expressing a recombinant receptor from a modified TGFBR2 Locus, related polynucleotides and methods
|
|
EP3962519A1
(en)
|
2019-05-01 |
2022-03-09 |
Juno Therapeutics, Inc. |
Cells expressing a chimeric receptor from a modified cd247 locus, related polynucleotides and methods
|
|
US20200384027A1
(en)
|
2019-05-03 |
2020-12-10 |
Kite Pharma, Inc. |
Methods of administering chimeric antigen receptor immunotherapy
|
|
CA3139346A1
(en)
|
2019-05-07 |
2020-11-12 |
Gracell Biotechnologies (Shanghai) Co., Ltd. |
Engineered immune cell targeting bcma and use thereof
|
|
US11162079B2
(en)
|
2019-05-10 |
2021-11-02 |
The Regents Of The University Of California |
Blood type O Rh-hypo-immunogenic pluripotent cells
|
|
US20220235340A1
(en)
|
2019-05-20 |
2022-07-28 |
The Broad Institute, Inc. |
Novel crispr-cas systems and uses thereof
|
|
PE20220568A1
(es)
|
2019-05-21 |
2022-04-20 |
Novartis Ag |
Moleculas de union a cd19 y usos de las mismas
|
|
CA3141162A1
(en)
|
2019-05-22 |
2020-11-26 |
Leidos, Inc. |
Lag3 binding peptides
|
|
US11453681B2
(en)
|
2019-05-23 |
2022-09-27 |
Gilead Sciences, Inc. |
Substituted eneoxindoles and uses thereof
|
|
EP3973072A1
(en)
|
2019-05-23 |
2022-03-30 |
Vogelsang, Matjaz |
Method for removal of nucleic acids impurities from liquid composition comprising genetically engineered particles or proteins
|
|
CN114051532A
(zh)
*
|
2019-05-24 |
2022-02-15 |
希望之城公司 |
用于治疗ccr4阳性恶性肿瘤的经ccr4靶向性嵌合抗原受体修饰的t细胞
|
|
US20220226464A1
(en)
|
2019-05-28 |
2022-07-21 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating immune responses
|
|
WO2020243423A1
(en)
|
2019-05-31 |
2020-12-03 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
JPWO2020246563A1
(https=)
*
|
2019-06-05 |
2020-12-10 |
|
|
|
AU2020286471B2
(en)
*
|
2019-06-07 |
2025-07-31 |
The Trustees Of The University Of Pennsylvania |
Dual CAR expressing T cells individually linked to CD28 and 4-1BB
|
|
MX2021015125A
(es)
|
2019-06-07 |
2022-04-06 |
Juno Therapeutics Inc |
Cultivo automatizado de celulas t.
|
|
WO2020251972A1
(en)
|
2019-06-10 |
2020-12-17 |
Kymera Therapeutics, Inc. |
Smarca degraders and uses thereof
|
|
EP3983538A1
(en)
|
2019-06-12 |
2022-04-20 |
Obsidian Therapeutics, Inc. |
Ca2 compositions and methods for tunable regulation
|
|
EP3983537A1
(en)
|
2019-06-12 |
2022-04-20 |
Obsidian Therapeutics, Inc. |
Ca2 compositions and methods for tunable regulation
|
|
EP3983006A1
(en)
|
2019-06-12 |
2022-04-20 |
Juno Therapeutics, Inc. |
Combination therapy of a cell-mediated cytotoxic therapy and an inhibitor of a prosurvival bcl2 family protein
|
|
WO2020257823A2
(en)
|
2019-06-21 |
2020-12-24 |
Kite Pharma, Inc. |
TGF-β RECEPTORS AND METHODS OF USE
|
|
AU2020301413A1
(en)
|
2019-06-24 |
2022-02-10 |
Children's Hospital Los Angeles |
BCL11B overexpression to enhance human thymopoiesis T cell function
|
|
CR20210687A
(es)
|
2019-06-25 |
2022-03-03 |
Gilead Sciences Inc |
PROTEÍNAS DE FUSIÓN FLT3L-Fc Y MÉTODOS DE USO
|
|
JP2022538974A
(ja)
|
2019-06-26 |
2022-09-07 |
マサチューセッツ インスチテュート オブ テクノロジー |
免疫調節融合タンパク質-金属水酸化物錯体およびその方法
|
|
BR112021026517A2
(pt)
|
2019-06-28 |
2022-05-10 |
Kymera Therapeutics Inc |
Degradadores de irak e usos dos mesmos
|
|
WO2021003297A1
(en)
|
2019-07-02 |
2021-01-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind egfrviii and their use
|
|
JP2022539248A
(ja)
|
2019-07-02 |
2022-09-07 |
フレッド ハッチンソン キャンサー リサーチ センター |
組換えad35ベクター及び関連遺伝子治療改善
|
|
GB201909573D0
(en)
|
2019-07-03 |
2019-08-14 |
Cancer Research Tech Ltd |
Modulation of T cell cytotoxicity and related therapy
|
|
JPWO2021010326A1
(https=)
|
2019-07-12 |
2021-01-21 |
|
|
|
WO2021011868A1
(en)
|
2019-07-17 |
2021-01-21 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
US20220267726A1
(en)
|
2019-07-18 |
2022-08-25 |
Gpb Scientific, Inc. |
Ordered processing of blood products to produce therapeutically active cells
|
|
US20220251572A1
(en)
|
2019-07-23 |
2022-08-11 |
Mnemo Therapeutics |
Immune cells defective for suv39h1
|
|
MX2022000896A
(es)
|
2019-07-24 |
2022-02-14 |
Regeneron Pharma |
Receptores de antigenos quimericos con especificidad por mage-a4 y usos de los mismos.
|
|
JP7669346B2
(ja)
|
2019-07-30 |
2025-04-28 |
ユニバーシティー ヘルス ネットワーク |
T細胞受容体及びその使用方法
|
|
MX2022001210A
(es)
|
2019-07-30 |
2022-05-03 |
Univ Health Network |
Moléculas de complejo mayor de histocompatibilidad (mhc) de clase ii y métodos para su uso.
|
|
US20220281948A1
(en)
|
2019-07-30 |
2022-09-08 |
University Health Network |
Mhc class ii molecules and methods of use thereof
|
|
TWI860386B
(zh)
|
2019-07-30 |
2024-11-01 |
英商拜西可泰克斯有限公司 |
異質雙環肽複合物
|
|
CN110305849B
(zh)
*
|
2019-08-01 |
2021-03-30 |
广东万海细胞生物科技有限公司 |
稳定表达car的t细胞及其制备方法与应用
|
|
GB201911066D0
(en)
|
2019-08-02 |
2019-09-18 |
Achilles Therapeutics Ltd |
T cell therapy
|
|
JP7739261B2
(ja)
*
|
2019-08-09 |
2025-09-16 |
エイ2・バイオセラピューティクス・インコーポレイテッド |
ヘテロ接合性の喪失に応答する細胞表面受容体
|
|
WO2021030627A1
(en)
|
2019-08-13 |
2021-02-18 |
The General Hospital Corporation |
Methods for predicting outcomes of checkpoint inhibition and treatment thereof
|
|
US12421557B2
(en)
|
2019-08-16 |
2025-09-23 |
The Broad Institute, Inc. |
Methods for predicting outcomes and treating colorectal cancer using a cell atlas
|
|
JP2022545467A
(ja)
|
2019-08-22 |
2022-10-27 |
ジュノー セラピューティクス インコーポレイテッド |
T細胞療法とzesteホモログ2エンハンサー(EZH2)阻害剤との併用療法および関連方法
|
|
EP4021485A1
(en)
*
|
2019-08-28 |
2022-07-06 |
King's College London |
B cell targeted parallel car (pcar) therapeutic agents
|
|
US20230092895A1
(en)
|
2019-08-30 |
2023-03-23 |
Obsidian Therapeutics, Inc. |
Tandem cd19 car-based compositions and methods for immunotherapy
|
|
WO2021041922A1
(en)
|
2019-08-30 |
2021-03-04 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
|
EP4022637A2
(en)
|
2019-08-30 |
2022-07-06 |
Juno Therapeutics, Inc. |
Machine learning methods for classifying cells
|
|
EP4025244A1
(en)
|
2019-09-02 |
2022-07-13 |
Institut Curie |
Immunotherapy targeting tumor neoantigenic peptides
|
|
KR20220054383A
(ko)
|
2019-09-03 |
2022-05-02 |
알로젠 테라퓨틱스 인코포레이티드 |
T 세포 요법을 위한 t 세포를 제조하는 방법
|
|
AU2020341454A1
(en)
|
2019-09-03 |
2022-03-10 |
Sana Biotechnology, Inc. |
CD24-associated particles and related methods and uses thereof
|
|
WO2021046451A1
(en)
|
2019-09-06 |
2021-03-11 |
Obsidian Therapeutics, Inc. |
Compositions and methods for dhfr tunable protein regulation
|
|
CA3153700A1
(en)
|
2019-09-09 |
2021-03-18 |
Scribe Therapeutics Inc. |
Compositions and methods for use in immunotherapy
|
|
CA3150224A1
(en)
|
2019-09-10 |
2021-03-18 |
Obsidian Therapeutics, Inc. |
Ca2 compositions and methods for tunable regulation
|
|
CN112480263A
(zh)
*
|
2019-09-12 |
2021-03-12 |
普米斯生物技术(苏州)有限公司 |
一种双特异t细胞激活器活化t细胞的设计及其应用
|
|
CN114945366B
(zh)
|
2019-09-13 |
2025-01-07 |
林伯士萨顿公司 |
Hpk1拮抗剂和其用途
|
|
WO2021051088A1
(en)
*
|
2019-09-13 |
2021-03-18 |
Ohio State Innovation Foundation |
Nk cell immunotherapy compositions, methods of making and methods of using same
|
|
US20220348651A1
(en)
|
2019-09-18 |
2022-11-03 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
US20230127263A1
(en)
*
|
2019-09-20 |
2023-04-27 |
The University Of North Carolina At Chapel Hill |
Modified t cells and methods of preparing the same
|
|
JP2023501871A
(ja)
|
2019-09-20 |
2023-01-20 |
上海吉倍生物技術有限公司 |
Bcma標的化抗体及びキメラ抗原受容体
|
|
WO2021061648A1
(en)
|
2019-09-23 |
2021-04-01 |
Massachusetts Institute Of Technology |
Methods and compositions for stimulation of endogenous t cell responses
|
|
KR102685211B1
(ko)
*
|
2019-09-26 |
2024-07-16 |
주식회사 헬릭스미스 |
항-c-Met 항체 또는 그의 항원 결합 단편을 포함하는 키메라 항원 수용체, 및 이의 용도
|
|
US12297426B2
(en)
|
2019-10-01 |
2025-05-13 |
The Broad Institute, Inc. |
DNA damage response signature guided rational design of CRISPR-based systems and therapies
|
|
KR102287180B1
(ko)
*
|
2019-10-01 |
2021-08-09 |
충북대학교 산학협력단 |
Cd138에 특이적으로 결합하는 키메릭 항원 수용체, 이를 발현하는 면역세포 및 이의 항암 용도
|
|
US12394502B2
(en)
|
2019-10-02 |
2025-08-19 |
The General Hospital Corporation |
Method for predicting HLA-binding peptides using protein structural features
|
|
AU2020358863A1
(en)
|
2019-10-03 |
2022-05-12 |
Celyntra Therapeutics Sa |
CRISPR systems with engineered dual guide nucleic acids
|
|
US12195725B2
(en)
|
2019-10-03 |
2025-01-14 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for modulating and detecting tissue specific TH17 cell pathogenicity
|
|
US11981922B2
(en)
|
2019-10-03 |
2024-05-14 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment
|
|
US11793787B2
(en)
|
2019-10-07 |
2023-10-24 |
The Broad Institute, Inc. |
Methods and compositions for enhancing anti-tumor immunity by targeting steroidogenesis
|
|
CN114555123B
(zh)
|
2019-10-18 |
2024-04-02 |
四十七公司 |
用于治疗骨髓增生异常综合征和急性髓系白血病的联合疗法
|
|
WO2021078910A1
(en)
|
2019-10-22 |
2021-04-29 |
Institut Curie |
Immunotherapy targeting tumor neoantigenic peptides
|
|
EP4048696A1
(en)
|
2019-10-23 |
2022-08-31 |
Kite Pharma, Inc. |
Anti-idiotypic antigen binding molecules and methods of use thereof
|
|
CN110679588A
(zh)
*
|
2019-10-23 |
2020-01-14 |
厦门生命互联科技有限公司 |
一种嵌合抗原受体t细胞冻存介质及用途
|
|
TWI717880B
(zh)
|
2019-10-24 |
2021-02-01 |
中國醫藥大學附設醫院 |
Hla-g特異性嵌合抗原受體、核酸、hla-g特異性嵌合抗原受體表達質體、表達hla-g特異性嵌合抗原受體細胞、其用途以及用於治療癌症之醫藥組合物
|
|
WO2021084050A1
(en)
|
2019-10-30 |
2021-05-06 |
Juno Therapeutics Gmbh |
Cell selection and/or stimulation devices and methods of use
|
|
US11844800B2
(en)
|
2019-10-30 |
2023-12-19 |
Massachusetts Institute Of Technology |
Methods and compositions for predicting and preventing relapse of acute lymphoblastic leukemia
|
|
KR20220091576A
(ko)
|
2019-10-31 |
2022-06-30 |
포티 세븐, 인코포레이티드 |
혈액암의 항-cd47 및 항-cd20 기반 치료
|
|
EP4070855B1
(en)
|
2019-11-01 |
2025-12-24 |
Kyoto Prefectural Public University Corporation |
B-cell antibody receptor and use thereof
|
|
IL292665B2
(en)
|
2019-11-06 |
2026-02-01 |
Kite Pharma Inc |
Chimeric antigen receptor T cell therapy
|
|
IL292667B1
(en)
|
2019-11-07 |
2026-02-01 |
Juno Therapeutics Inc |
Combination of T-cell therapy and (s)-3-[4-(4-morpholin-4-ylmethyl-benzyloxy)-l-oxo-3,l-dihydro-isoindol-2-yl]-piperidine-6,2-dione
|
|
US12195723B2
(en)
|
2019-11-08 |
2025-01-14 |
The Broad Institute, Inc. |
Engineered antigen presenting cells and uses thereof
|
|
TWI778443B
(zh)
|
2019-11-12 |
2022-09-21 |
美商基利科學股份有限公司 |
Mcl1抑制劑
|
|
JP7543404B2
(ja)
|
2019-11-20 |
2024-09-02 |
ジーアイ・セル・インコーポレイテッド |
T細胞培養用培地組成物及びこれを用いたt細胞の培養方法
|
|
IL292924A
(en)
|
2019-11-26 |
2022-07-01 |
Novartis Ag |
Chimeric antigen receptors cd19 and cd22 and their uses
|
|
EP4065605A4
(en)
|
2019-11-26 |
2023-07-12 |
Ramot at Tel-Aviv University Ltd. |
Antibodies to carbohydrate antigens
|
|
PH12022551291A1
(en)
|
2019-11-26 |
2023-11-20 |
Novartis Ag |
Chimeric antigen receptors binding bcma and cd19 and uses thereof
|
|
PT4065582T
(pt)
|
2019-11-26 |
2025-05-22 |
Ikena Oncology Inc |
Derivados polimórficos do carbazol e utilizações dos mesmos
|
|
KR20220122656A
(ko)
|
2019-12-06 |
2022-09-02 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Gprc5d-표적화 결합 도메인에 대한 항-이디오타입 항체 및 관련 조성물 및 방법
|
|
IL293393A
(en)
|
2019-12-06 |
2022-07-01 |
Juno Therapeutics Inc |
Cell therapy-related toxicity and response-related methods for the treatment of b-cell malignancies
|
|
CN115916817A
(zh)
|
2019-12-06 |
2023-04-04 |
朱诺治疗学股份有限公司 |
针对bcma靶向结合结构域的抗独特型抗体及相关组合物和方法
|
|
US12522651B2
(en)
|
2019-12-09 |
2026-01-13 |
Versiti Blood Research Institute Foundation, Inc. |
BCG car constructs and methods of their manufacture and use
|
|
US12551564B2
(en)
|
2019-12-10 |
2026-02-17 |
Kymera Therapeutics, Inc. |
IRAK degraders and uses thereof
|
|
WO2021127190A1
(en)
|
2019-12-17 |
2021-06-24 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
WO2021127283A2
(en)
|
2019-12-17 |
2021-06-24 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
MX2022007759A
(es)
|
2019-12-20 |
2022-07-19 |
Novartis Ag |
Combinacion del anticuerpo anti tim-3 mbg453 y anticuerpo anti tgf-beta nis793, con o sin decitabina o el anticuerpo anti pd-1 spartalizumab, para el tratamiento de mielofibrosis y sindrome mielodisplasico.
|
|
BR112022012410A2
(pt)
|
2019-12-23 |
2022-08-30 |
Kymera Therapeutics Inc |
Degradadores smarca e usos dos mesmos
|
|
WO2021133917A1
(en)
|
2019-12-23 |
2021-07-01 |
Kymera Therapeutics, Inc. |
Smarca inhibitors and uses thereof
|
|
LT4081305T
(lt)
|
2019-12-24 |
2024-11-25 |
Carna Biosciences, Inc. |
Diacilglicerolio kinazę moduliuojantys junginiai
|
|
JP7088902B2
(ja)
*
|
2019-12-27 |
2022-06-21 |
クレージュ メディカル カンパニー,リミテッド |
キメラ抗原受容体タンパク質をコードする核酸およびキメラ抗原受容体タンパク質を発現するtリンパ球
|
|
US20230028754A1
(en)
|
2019-12-28 |
2023-01-26 |
Gpb Scientific, Inc. |
Microfluidic cartridges for processing particles and cells
|
|
CN116234829A
(zh)
|
2020-01-03 |
2023-06-06 |
马伦戈治疗公司 |
抗tcr抗体分子及其用途
|
|
CN113150167A
(zh)
*
|
2020-01-22 |
2021-07-23 |
中国人民解放军总医院第五医学中心 |
一种能够反转pd-1免疫抑制信号的car t细胞结构em1设计
|
|
US12165747B2
(en)
|
2020-01-23 |
2024-12-10 |
The Broad Institute, Inc. |
Molecular spatial mapping of metastatic tumor microenvironment
|
|
AU2021211713A1
(en)
|
2020-01-23 |
2022-08-25 |
The Children's Medical Center Corporation |
Stroma-free T cell differentiation from human pluripotent stem cells
|
|
IL294988A
(en)
|
2020-01-24 |
2022-09-01 |
Regeneron Pharma |
Antigen preferentially expressed in melanoma t-cell receptors (prame) and methods of using them
|
|
JP2023513434A
(ja)
|
2020-01-24 |
2023-03-31 |
ジュノー セラピューティクス インコーポレイテッド |
養子細胞療法における投与ならびに濾胞性リンパ腫および辺縁帯リンパ腫の処置のための方法
|
|
US20230090117A1
(en)
|
2020-01-28 |
2023-03-23 |
Juno Therapeutics, Inc. |
Methods for t cell transduction
|
|
EP4100422A1
(en)
|
2020-02-03 |
2022-12-14 |
MVZ Prof. Niendorf Pathologie Hamburg-West GmbH |
Marker set for the diagnosis and treatment of cancer
|
|
AU2021217003A1
(en)
|
2020-02-04 |
2022-09-15 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Anti-dinitrophenol chimeric antigen receptors
|
|
IL295381B1
(en)
|
2020-02-12 |
2026-04-01 |
Juno Therapeutics Inc |
BCMA-directed chimeric T-cell antigen receptor compounds and methods and uses thereof
|
|
IL295384B1
(en)
|
2020-02-12 |
2026-04-01 |
Juno Therapeutics Inc |
T-cell preparations with chimeric antigen receptor directed against CD19 and methods and uses thereof
|
|
JP2023513606A
(ja)
|
2020-02-14 |
2023-03-31 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
核酸を評価するための方法および材料
|
|
KR20260017503A
(ko)
|
2020-02-14 |
2026-02-05 |
길리애드 사이언시즈, 인코포레이티드 |
Ccr8에 결합하는 항체 및 융합 단백질, 및 이의 용도
|
|
WO2021167908A1
(en)
|
2020-02-17 |
2021-08-26 |
Board Of Regents, The University Of Texas System |
Methods for expansion of tumor infiltrating lymphocytes and use thereof
|
|
US12076343B2
(en)
|
2020-02-19 |
2024-09-03 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Engineered safety in cell therapy
|
|
KR20220147109A
(ko)
|
2020-02-27 |
2022-11-02 |
노파르티스 아게 |
키메라 항원 수용체 발현 세포의 제조 방법
|
|
KR20220146530A
(ko)
|
2020-02-27 |
2022-11-01 |
노파르티스 아게 |
키메라 항원 수용체-발현 세포의 제조 방법
|
|
CN111269326A
(zh)
*
|
2020-02-28 |
2020-06-12 |
南京北恒生物科技有限公司 |
新型嵌合抗原受体及其用途
|
|
AU2021230289A1
(en)
|
2020-03-03 |
2022-09-29 |
PIC Therapeutics, Inc. |
eIF4E inhibitors and uses thereof
|
|
IL296103A
(en)
|
2020-03-05 |
2022-11-01 |
Neotx Therapeutics Ltd |
Methods and compositions for treating cancer with immune cells
|
|
US11896619B2
(en)
|
2020-03-10 |
2024-02-13 |
Massachusetts Institute Of Technology |
Compositions and methods for immunotherapy of NPM1c-positive cancer
|
|
KR20240096884A
(ko)
|
2020-03-10 |
2024-06-26 |
매사추세츠 인스티튜트 오브 테크놀로지 |
조작된 기억-유사 nk 세포 및 이의 조성물을 생성하기 위한 방법
|
|
CA3171250A1
(en)
|
2020-03-10 |
2021-09-16 |
E. Lynne KELLEY |
Methods for treating neutropenia
|
|
CN113402612A
(zh)
|
2020-03-17 |
2021-09-17 |
西比曼生物科技(香港)有限公司 |
靶向cd19和cd20的联合嵌合抗原受体及其应用
|
|
US12528785B2
(en)
|
2020-03-19 |
2026-01-20 |
Kymera Therapeutics, Inc. |
MDM2 degraders and uses thereof
|
|
JP2023521663A
(ja)
|
2020-03-31 |
2023-05-25 |
サナ バイオテクノロジー,インコーポレイテッド |
標的化脂質粒子及び組成物ならびにその使用
|
|
EP3892720A1
(en)
|
2020-04-06 |
2021-10-13 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Presenting cell and use thereof in cell therapy
|
|
KR20230009386A
(ko)
|
2020-04-10 |
2023-01-17 |
주노 쎄러퓨티크스 인코퍼레이티드 |
B-세포 성숙 항원을 표적화하는 키메라 항원 수용체로 조작된 세포 요법 관련 방법 및 용도
|
|
US20230340040A1
(en)
*
|
2020-04-14 |
2023-10-26 |
St. Jude Children's Research Hospital, Inc. |
Chimeric myd88 receptors
|
|
US12241086B2
(en)
*
|
2020-04-15 |
2025-03-04 |
Amgen Inc. |
Process for generating genetically engineered autologous T cells
|
|
US12378521B2
(en)
|
2020-04-15 |
2025-08-05 |
Amgen Inc. |
Method for enhancing production of genetically engineered autologous T cells
|
|
EP4136228A4
(en)
|
2020-04-15 |
2024-09-11 |
California Institute of Technology |
THERMAL REGULATION OF T-CELL IMMUNOTHERAPY BY MOLECULAR AND PHYSICAL ACTUATION
|
|
GB202005599D0
(en)
|
2020-04-17 |
2020-06-03 |
Univ London |
Modulation of t cell cytotoxicity and related therapy
|
|
CN116157125A
(zh)
|
2020-04-28 |
2023-05-23 |
朱诺治疗学股份有限公司 |
针对bcma的t细胞疗法与免疫调节化合物的组合
|
|
WO2021219990A1
(en)
|
2020-04-28 |
2021-11-04 |
Achilles Therapeutics Uk Limited |
T cell therapy
|
|
GB202006254D0
(en)
|
2020-04-28 |
2020-06-10 |
Institute Of Cancer Res |
Anti-cancer vaccines and related therapy
|
|
US12433954B2
(en)
|
2020-05-01 |
2025-10-07 |
Massachusetts Institute Of Technology |
Methods of activating anti-CD19 chimeric antigen receptor (CAR) T cells using amphiphilic ligand conjugates comprising CAR-targeting protein sequence motifs
|
|
JP7564888B2
(ja)
|
2020-05-01 |
2024-10-09 |
ギリアード サイエンシーズ, インコーポレイテッド |
Cd73阻害性2,4-ジオキソピリミジン化合物
|
|
US20210340524A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
|
US12497623B2
(en)
|
2020-05-04 |
2025-12-16 |
The Trustees Of The University Of Pennsylvania |
Non-signaling HIV fusion inhibitors and methods of use thereof
|
|
AU2021266706A1
(en)
|
2020-05-05 |
2022-12-15 |
Regeneron Pharmaceuticals, Inc. |
Car comprising CD28 zeta and CD3 zeta
|
|
WO2021228999A1
(en)
|
2020-05-12 |
2021-11-18 |
Institut Curie |
Neoantigenic epitopes associated with sf3b1 mutations
|
|
WO2021231661A2
(en)
|
2020-05-13 |
2021-11-18 |
Juno Therapeutics, Inc. |
Process for producing donor-batched cells expressing a recombinant receptor
|
|
JP7727662B2
(ja)
|
2020-05-13 |
2025-08-21 |
ジュノー セラピューティクス インコーポレイテッド |
臨床応答に関連する特徴量の特定方法およびその使用
|
|
US20230190780A1
(en)
*
|
2020-05-15 |
2023-06-22 |
Precision Biosciences, Inc. |
Methods for immunotherapy
|
|
AU2021275239A1
(en)
|
2020-05-21 |
2022-12-15 |
Board Of Regents, The University Of Texas System |
T cell receptors with VGLL1 specificity and uses thereof
|
|
IL298558A
(en)
|
2020-05-27 |
2023-01-01 |
Antion Biosciences Sa |
Adapter molecules redirect CAR T cells to the antigen of interest
|
|
US12043654B2
(en)
|
2020-06-02 |
2024-07-23 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Anti-GCC antibody and CAR thereof for treating digestive system cancer
|
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
|
WO2021247897A1
(en)
|
2020-06-03 |
2021-12-09 |
Kymera Therapeutics, Inc. |
Deuterated irak degraders and uses thereof
|
|
CN115867294A
(zh)
|
2020-06-04 |
2023-03-28 |
凯瑞斯马治疗公司 |
嵌合抗原受体的新型构建体
|
|
WO2021244654A1
(en)
*
|
2020-06-05 |
2021-12-09 |
Nanjing Legend Biotech Co., Ltd. |
Activation induced cytokine production in immune cells
|
|
US20220057381A1
(en)
|
2020-06-08 |
2022-02-24 |
Janssen Biotech, Inc. |
Cell-based assay for determining the in vitro tumor killing activity of chimeric antigen expressing immune cells
|
|
CN116367857A
(zh)
|
2020-06-08 |
2023-06-30 |
米纳瓦生物技术公司 |
抗nme抗体及治疗癌症或癌症转移的方法
|
|
CA3185455A1
(en)
|
2020-06-11 |
2021-12-16 |
Novartis Ag |
Zbtb32 inhibitors and uses thereof
|
|
WO2021262723A1
(en)
*
|
2020-06-22 |
2021-12-30 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with tslpr-cd19 or tslpr-cd22 immunotherapy
|
|
CN115916199A
(zh)
|
2020-06-23 |
2023-04-04 |
诺华股份有限公司 |
包含3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物的给药方案
|
|
US20230293530A1
(en)
|
2020-06-24 |
2023-09-21 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
|
EP4171616A1
(en)
|
2020-06-26 |
2023-05-03 |
Juno Therapeutics GmbH |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
|
KR20230028796A
(ko)
|
2020-06-26 |
2023-03-02 |
미네르바 바이오테크놀로지 코포레이션 |
항-nme 항체 및 암 또는 암 전이의 치료 방법
|
|
AU2021308078A1
(en)
|
2020-07-17 |
2023-02-09 |
Children's Hospital Los Angeles |
Chimeric MyD88 receptors for redirecting immunosuppressive signaling and related compositions and methods
|
|
KR102297396B1
(ko)
|
2020-07-29 |
2021-09-06 |
(주)티카로스 |
면역시냅스를 안정화시키는 키메라 항원 수용체(car) t 세포
|
|
CA3190266A1
(en)
|
2020-07-30 |
2022-02-03 |
Institut Curie |
Immune cells defective for socs1
|
|
WO2022026496A2
(en)
|
2020-07-31 |
2022-02-03 |
Leidos, Inc. |
Lag3 binding peptides
|
|
IL300248A
(en)
|
2020-08-03 |
2023-03-01 |
Bicycletx Ltd |
peptide-based linkers
|
|
US20230271940A1
(en)
|
2020-08-03 |
2023-08-31 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
WO2022029660A1
(en)
|
2020-08-05 |
2022-02-10 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to ror1-targeted binding domains and related compositions and methods
|
|
IL300516A
(en)
|
2020-08-13 |
2023-04-01 |
Sana Biotechnology Inc |
Methods for treating susceptible patients with hypoimmunogenic cells, and related methods and compounds
|
|
JP2023538303A
(ja)
|
2020-08-13 |
2023-09-07 |
イェール ユニバーシティー |
所望の表現型を有するcar t細胞の操作および選択のための組成物および方法
|
|
KR20230084470A
(ko)
|
2020-08-14 |
2023-06-13 |
카이트 파마 인코포레이티드 |
면역 세포 기능의 향상
|
|
WO2022038158A1
(en)
|
2020-08-17 |
2022-02-24 |
Bicycletx Limited |
Bicycle conjugates specific for nectin-4 and uses thereof
|
|
WO2022040454A1
(en)
|
2020-08-20 |
2022-02-24 |
A2 Biotherapeutics, Inc. |
Compositions and methods for treating mesothelin positive cancers
|
|
KR102859550B1
(ko)
|
2020-08-20 |
2025-09-16 |
에이투 바이오쎄라퓨틱스, 인크. |
Ceacam 양성 암을 치료하기 위한 조성물 및 방법
|
|
KR20230054391A
(ko)
|
2020-08-21 |
2023-04-24 |
12343096 캐나다 인코포레이티드 |
모듈러 조립 수용체 및 그의 용도
|
|
US20230302155A1
(en)
|
2020-08-21 |
2023-09-28 |
Novartis Ag |
Compositions and methods for in vivo generation of car expressing cells
|
|
US12152251B2
(en)
|
2020-08-25 |
2024-11-26 |
Kite Pharma, Inc. |
T cells with improved functionality
|
|
US20230302135A1
(en)
*
|
2020-08-26 |
2023-09-28 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Hybrid allosteric receptor-engineered stem cells
|
|
WO2022081426A1
(en)
|
2020-10-12 |
2022-04-21 |
Leidos, Inc. |
Immunomodulatory peptides
|
|
JP2023545472A
(ja)
*
|
2020-10-16 |
2023-10-30 |
ネオンク テクノロジーズ インク. |
Cns感染症の治療のためのpohとレムデシビルとの組み合わせ
|
|
WO2022086620A1
(en)
|
2020-10-20 |
2022-04-28 |
The Methodist Hospital System |
Psma-targeted immunotherapies for cancers
|
|
EP4232071A4
(en)
|
2020-10-23 |
2024-08-28 |
Asher Biotherapeutics, Inc. |
FUSIONS WITH CD8 ANTIGEN-BINDING MOLECULES TO MODULATE IMMUNE CELL FUNCTION
|
|
US20220155299A1
(en)
|
2020-10-28 |
2022-05-19 |
Kite Pharma, Inc. |
Flow cytometric method for characterization of t-cell impurities
|
|
US20250215081A1
(en)
|
2020-11-06 |
2025-07-03 |
Novartis Ag |
Anti-cd19 agent and b cell targeting agent combination therapy for treating b cell malignancies
|
|
CA3201499A1
(en)
|
2020-11-13 |
2022-05-19 |
Catamaran Bio, Inc. |
Genetically modified natural killer cells and methods of use thereof
|
|
KR20230107617A
(ko)
|
2020-11-13 |
2023-07-17 |
노파르티스 아게 |
키메라 항원 수용체(car)-발현 세포를 사용한 병용 요법
|
|
CN112195250A
(zh)
*
|
2020-11-20 |
2021-01-08 |
山东省医学科学院附属医院 |
一种qPCR试剂盒及应用
|
|
WO2022115492A1
(en)
|
2020-11-24 |
2022-06-02 |
Lyell Immunopharma, Inc. |
Methods for making, compositions comprising, and methods of using rejuvenated t cells
|
|
WO2022120353A1
(en)
|
2020-12-02 |
2022-06-09 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
|
AU2021392032A1
(en)
|
2020-12-03 |
2023-06-22 |
Century Therapeutics, Inc. |
Genetically engineered cells and uses thereof
|
|
EP4259144A4
(en)
|
2020-12-09 |
2025-08-20 |
Kymera Therapeutics Inc |
SMARCA DEGRADING AGENTS AND THEIR USES
|
|
WO2022133030A1
(en)
|
2020-12-16 |
2022-06-23 |
Juno Therapeutics, Inc. |
Combination therapy of a cell therapy and a bcl2 inhibitor
|
|
AR124414A1
(es)
|
2020-12-18 |
2023-03-22 |
Century Therapeutics Inc |
Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
|
|
AU2021410635A1
(en)
|
2020-12-24 |
2023-06-29 |
Kite Pharma, Inc. |
Prostate cancer chimeric antigen receptors
|
|
PH12023500015A1
(en)
|
2020-12-30 |
2024-03-11 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
EP4271817A2
(en)
|
2020-12-30 |
2023-11-08 |
Alaunos Therapeutics, Inc. |
Recombinant vectors comprising polycistronic expression cassettes and methods of use thereof
|
|
CA3200509A1
(en)
|
2020-12-31 |
2022-07-07 |
Sonja SCHREPFER |
Methods and compositions for modulating car-t activity
|
|
US12576400B2
(en)
|
2021-01-08 |
2026-03-17 |
Cellanome, Inc. |
Methods for incubating and analyzing a cell in a compartment of a fluidic device
|
|
JP2024502618A
(ja)
|
2021-01-08 |
2024-01-22 |
セラノーム, インコーポレイテッド |
生体試料を分析するためのデバイスおよび方法
|
|
WO2022150582A1
(en)
|
2021-01-10 |
2022-07-14 |
Kite Pharma, Inc. |
T cell therapy
|
|
US20250186539A2
(en)
|
2021-01-11 |
2025-06-12 |
Bicycletx Limited |
Methods for treating cancer
|
|
EP4274901A1
(en)
|
2021-01-11 |
2023-11-15 |
Sana Biotechnology, Inc. |
Use of cd8-targeted viral vectors
|
|
JP2024505428A
(ja)
|
2021-01-14 |
2024-02-06 |
アンスティテュ キュリー |
Her2単一ドメイン抗体バリアントおよびそのcar
|
|
UY39610A
(es)
|
2021-01-20 |
2022-08-31 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
|
CN117062611A
(zh)
*
|
2021-01-26 |
2023-11-14 |
惠和生物技术(上海)有限公司 |
嵌合抗原受体(car)构建体和表达car构建体的nk细胞
|
|
CA3209218A1
(en)
*
|
2021-01-27 |
2022-08-04 |
H. Lee Moffitt Cancer Center And Research Institute Inc. |
Bi-specific car t cells for b cell malignancies
|
|
AU2022212090A1
(en)
|
2021-01-28 |
2023-07-06 |
Allogene Therapeutics, Inc. |
Methods for transducing immune cells
|
|
FI4284512T3
(fi)
|
2021-01-28 |
2025-05-22 |
Regeneron Pharma |
Koostumuksia ja menetelmiä sytokiinien vapautumisoireyhtymän hoitamiseksi
|
|
JP2024506858A
(ja)
|
2021-02-02 |
2024-02-15 |
リミナル・バイオサイエンシーズ・リミテッド |
Gpr84アンタゴニストおよびその使用
|
|
CN117120090A
(zh)
|
2021-02-12 |
2023-11-24 |
林伯士萨顿公司 |
Hpk1拮抗剂和其用途
|
|
WO2022174268A1
(en)
|
2021-02-15 |
2022-08-18 |
Kymera Therapeutics, Inc. |
Irak4 degraders and uses thereof
|
|
CN116867494A
(zh)
|
2021-02-15 |
2023-10-10 |
凯麦拉医疗公司 |
Irak4降解剂和其用途
|
|
TW202241469A
(zh)
|
2021-02-20 |
2022-11-01 |
美商凱特製藥公司 |
免疫療法
|
|
EP4298212A4
(en)
|
2021-02-25 |
2026-04-15 |
Celyntra Therapeutics Sa |
Compositions and methods for targeting, editing, or modifying genes
|
|
JP2024509853A
(ja)
|
2021-03-03 |
2024-03-05 |
ジュノー セラピューティクス インコーポレイテッド |
T細胞療法およびdgk阻害剤の組合せ
|
|
CA3212530A1
(en)
|
2021-03-05 |
2022-09-09 |
Shanghai GenBase Biotechnology Co., Ltd. |
Anti-cldn6 antibody and use thereof
|
|
EP4301756A4
(en)
|
2021-03-05 |
2025-02-26 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
|
IL305571A
(en)
|
2021-03-11 |
2023-10-01 |
Kite Pharma Inc |
Improving the function of immune system cells
|
|
WO2022189639A1
(en)
|
2021-03-11 |
2022-09-15 |
Mnemo Therapeutics |
Tumor neoantigenic peptides and uses thereof
|
|
EP4304632A2
(en)
|
2021-03-11 |
2024-01-17 |
Mnemo Therapeutics |
Tumor neoantigenic peptides
|
|
US20250041412A1
(en)
|
2021-03-11 |
2025-02-06 |
Institut Curie |
Transmembrane neoantigenic peptides
|
|
WO2022196719A1
(ja)
|
2021-03-17 |
2022-09-22 |
第一三共株式会社 |
抗アセチルコリン受容体自己抗体に対するキメラ受容体をコードする遺伝子
|
|
KR20230159851A
(ko)
|
2021-03-22 |
2023-11-22 |
주노 쎄러퓨티크스 인코퍼레이티드 |
치료 세포 조성물의 효력을 결정하는 방법
|
|
CN117321200A
(zh)
|
2021-03-22 |
2023-12-29 |
朱诺治疗学股份有限公司 |
评估病毒载体颗粒效力的方法
|
|
CA3212948A1
(en)
|
2021-03-26 |
2022-09-29 |
David M. Hilbert |
Multifunctional immune cell therapies
|
|
US20240181052A1
(en)
|
2021-03-29 |
2024-06-06 |
Juno Therapeutics, Inc. |
Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
|
|
AU2022252220A1
(en)
|
2021-03-29 |
2023-10-12 |
Juno Therapeutics, Inc. |
Combination of a car t cell therapy and an immunomodulatory compound for treatment of lymphoma
|
|
WO2022213062A1
(en)
|
2021-03-29 |
2022-10-06 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
EP4320435A1
(en)
|
2021-04-09 |
2024-02-14 |
Achilles Therapeutics UK Limited |
Batch release assay for pharmaceutical products relating to t cell therapies
|
|
GB202109886D0
(en)
|
2021-07-08 |
2021-08-25 |
Achilles Therapeutics Uk Ltd |
Assay
|
|
AU2022256074A1
(en)
|
2021-04-09 |
2023-11-02 |
Nimbus Clio, Inc. |
Cbl-b modulators and uses thereof
|
|
TW202302145A
(zh)
|
2021-04-14 |
2023-01-16 |
美商基利科學股份有限公司 |
CD47/SIRPα結合及NEDD8活化酶E1調節次單元之共抑制以用於治療癌症
|
|
IL307612A
(en)
|
2021-04-16 |
2023-12-01 |
Celgene Corp |
Combined therapies with BCMA-directed T-cell therapy
|
|
KR20230171994A
(ko)
|
2021-04-16 |
2023-12-21 |
셀진 코포레이션 |
선행 줄기 세포 이식을 받은 환자에서의 t 세포 요법
|
|
JP2024514879A
(ja)
|
2021-04-16 |
2024-04-03 |
イケナ オンコロジー, インコーポレイテッド |
Mek阻害剤及びその使用
|
|
WO2022221126A1
(en)
|
2021-04-16 |
2022-10-20 |
Kite Pharma, Inc. |
Methods and systems for scheduling a patient-specific immunotherapy procedure
|
|
AU2022259428A1
(en)
|
2021-04-16 |
2023-10-26 |
Kite Pharma, Inc. |
Taci/bcma dual binding molecules
|
|
EP4326293A4
(en)
|
2021-04-22 |
2025-03-12 |
Baylor College of Medicine |
METHODS FOR MODIFYING IMMUNE CELLS HAVING REDUCED FRATRICIDAL ACTIVITY
|
|
AU2022261141A1
(en)
*
|
2021-04-23 |
2023-11-30 |
Myeloid Therapeutics, Inc. |
Compositions and methods for conditioning patients for cell therapy
|
|
EP4330381A1
(en)
|
2021-04-27 |
2024-03-06 |
Novartis AG |
Viral vector production system
|
|
CN117203328A
(zh)
|
2021-04-27 |
2023-12-08 |
武田药品工业株式会社 |
重组抗原呈递细胞
|
|
CA3217914A1
(en)
|
2021-05-04 |
2022-11-10 |
Kevin BRAY |
Chimeric antigen receptors with mage-a4 specificity and uses thereof
|
|
US20250283037A1
(en)
|
2021-05-06 |
2025-09-11 |
Juno Therapeutics Gmbh |
Methods for stimulating and transducing t cells
|
|
AU2022271290A1
(en)
|
2021-05-07 |
2023-11-23 |
Kymera Therapeutics, Inc. |
Cdk2 degraders and uses thereof
|
|
EP4337227A2
(en)
|
2021-05-14 |
2024-03-20 |
Kite Pharma, Inc. |
Chimeric antigen receptor t cell therapy
|
|
TW202313094A
(zh)
|
2021-05-18 |
2023-04-01 |
美商基利科學股份有限公司 |
使用FLT3L—Fc融合蛋白之方法
|
|
BR112023024231A2
(pt)
|
2021-05-19 |
2024-01-30 |
Sana Biotechnology Inc |
Células t primárias rhd negativas hipoimunogênicas
|
|
IL308696A
(en)
|
2021-05-24 |
2024-01-01 |
Kite Pharma Inc |
Nkg2d-based chimeric antgen receptor
|
|
WO2022251434A1
(en)
*
|
2021-05-26 |
2022-12-01 |
Emory University |
Jak inhibitors for managing conditions in patients with down's syndrome or other trisomy
|
|
AU2022283291A1
(en)
|
2021-05-27 |
2023-11-02 |
Sana Biotechnology, Inc. |
Hypoimmunogenic cells comprising engineered hla-e or hla-g
|
|
AU2022280957A1
(en)
|
2021-05-28 |
2023-11-30 |
Sana Biotechnology, Inc. |
Lipid particles containing a truncated baboon endogenous retrovirus (baev) envelope glycoprotein and related methods and uses
|
|
EP4419672A2
(en)
|
2021-06-01 |
2024-08-28 |
Artisan Development Labs, Inc. |
Compositions and methods for targeting, editing, or modifying genes
|
|
CA3218590A1
(en)
|
2021-06-07 |
2022-12-15 |
Providence Health & Services - Oregon |
Cxcr5, pd-1, and icos expressing tumor reactive cd4 t cells and their use
|
|
WO2022261061A1
(en)
|
2021-06-08 |
2022-12-15 |
Kite Pharma, Inc. |
Gpc3 binding molecules
|
|
EP4370676A2
(en)
|
2021-06-18 |
2024-05-22 |
Artisan Development Labs, Inc. |
Compositions and methods for targeting, editing or modifying human genes
|
|
WO2022269250A1
(en)
|
2021-06-22 |
2022-12-29 |
Achilles Therapeutics Uk Limited |
A method for producing antigen-specific t cells
|
|
WO2022271659A1
(en)
|
2021-06-23 |
2022-12-29 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
|
WO2022271677A1
(en)
|
2021-06-23 |
2022-12-29 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
|
CA3222277A1
(en)
|
2021-06-23 |
2022-12-29 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
|
KR20240005901A
(ko)
|
2021-06-23 |
2024-01-12 |
길리애드 사이언시즈, 인코포레이티드 |
디아실글리세롤 키나제 조절 화합물
|
|
US20240316104A1
(en)
|
2021-06-29 |
2024-09-26 |
Flagship Pioneering Innovations V, Inc. |
Immune cells engineered to promote thanotransmission and uses thereof
|
|
AU2022301302A1
(en)
|
2021-07-01 |
2024-01-25 |
Indapta Therapeutics, Inc. |
Engineered natural killer (nk) cells and related methods
|
|
WO2023278553A1
(en)
|
2021-07-01 |
2023-01-05 |
Kite Pharma, Inc. |
Closed-system and method for autologous and allogeneic cell therapy manufacturing
|
|
JP2024525485A
(ja)
|
2021-07-02 |
2024-07-12 |
カイト ファーマ インコーポレイテッド |
細胞療法適用において使用される遺伝子構築物由来の遺伝子産物におけるバリアントを特定するための方法
|
|
US20240368145A1
(en)
|
2021-07-09 |
2024-11-07 |
Immunic Ag |
Methods for treating cancer
|
|
KR20240046319A
(ko)
|
2021-07-14 |
2024-04-08 |
사나 바이오테크놀로지, 인크. |
저면역원성 세포에서의 y 염색체-연결 항원의 변경된 발현
|
|
MX2024000713A
(es)
*
|
2021-07-16 |
2024-03-25 |
Sana Biotechnology Inc |
Vectores policistrónicos para terapias a base de células.
|
|
WO2023004300A2
(en)
*
|
2021-07-19 |
2023-01-26 |
The Trustees Of The University Of Pennsylvania |
Chimeric antigen receptor (car)-t signaling optimization for tuning antigen activation threshold
|
|
US20230190799A1
(en)
*
|
2021-07-21 |
2023-06-22 |
City Of Hope |
Chimeric antigen receptor t cells targeting cea and anti-cea-il2 immunocytokines for cancer therapy
|
|
US20230268031A1
(en)
|
2021-07-30 |
2023-08-24 |
Kite Pharma, Inc. |
Monitoring and management of cell therapy-induced toxicities
|
|
US20250114452A1
(en)
|
2021-08-04 |
2025-04-10 |
The Regents Of The University Of Colorado, A Body Corporate |
Lat activating chimeric antigen receptor t cells and methods of use thereof
|
|
WO2023015217A1
(en)
|
2021-08-04 |
2023-02-09 |
Sana Biotechnology, Inc. |
Use of cd4-targeted viral vectors
|
|
US20240342280A1
(en)
*
|
2021-08-09 |
2024-10-17 |
The Trustees Of The University Of Pennsylvania |
Optimizing t cell differentiation state with micrornas
|
|
WO2023019226A1
(en)
|
2021-08-11 |
2023-02-16 |
Sana Biotechnology, Inc. |
Genetically modified cells for allogeneic cell therapy
|
|
TW202321435A
(zh)
|
2021-08-11 |
2023-06-01 |
美商薩那生物科技公司 |
用於改變低免疫原性細胞中之基因表現之可誘導系統
|
|
JP2024535677A
(ja)
|
2021-08-11 |
2024-10-02 |
サナ バイオテクノロジー,インコーポレイテッド |
即時血液媒介性炎症反応を減少させるための同種細胞療法を目的とした遺伝子改変細胞
|
|
AU2022325231A1
(en)
|
2021-08-11 |
2024-02-08 |
Sana Biotechnology, Inc. |
Genetically modified cells for allogeneic cell therapy to reduce complement-mediated inflammatory reactions
|
|
KR20240073006A
(ko)
|
2021-08-11 |
2024-05-24 |
사나 바이오테크놀로지, 인크. |
동종이계 세포 요법을 위한 유전자 변형된 1차 세포
|
|
WO2023021113A1
(en)
|
2021-08-18 |
2023-02-23 |
Julius-Maximilians-Universität Würzburg |
Hybrid tumor/cancer therapy based on targeting the resolution of or inducing transcription-replication conflicts (trcs)
|
|
JP2024531364A
(ja)
|
2021-08-20 |
2024-08-29 |
ノバルティス アーゲー |
キメラ抗原受容体発現細胞を作製する方法
|
|
WO2023021494A1
(en)
|
2021-08-20 |
2023-02-23 |
Rudd Christopher E |
Compositions and methods for anti-virus chimeric antigen receptor
|
|
US20240424096A1
(en)
|
2021-08-24 |
2024-12-26 |
Ecole Polytechnique Federale De Lausanne (Epfl) |
IL-10 Expressing Cells For Enhanced Cancer Immunotherapies
|
|
US12157732B2
(en)
|
2021-08-25 |
2024-12-03 |
PIC Therapeutics, Inc. |
eIF4E inhibitors and uses thereof
|
|
JP2024534127A
(ja)
|
2021-08-25 |
2024-09-18 |
ピク セラピューティクス, インコーポレイテッド |
eIF4E阻害剤及びその使用
|
|
WO2023049933A1
(en)
|
2021-09-27 |
2023-03-30 |
Sotio Biotech Inc. |
Chimeric receptor polypeptides in combination with trans metabolism molecules that re-direct glucose metabolites out of the glycolysis pathway and therapeutic uses thereof
|
|
AU2022366987A1
(en)
|
2021-10-14 |
2024-05-16 |
Arsenal Biosciences, Inc. |
Immune cells having co-expressed shrnas and logic gate systems
|
|
TWI863006B
(zh)
|
2021-10-18 |
2024-11-21 |
美商凱特製藥公司 |
用於嵌合抗原受體之信號傳導域
|
|
US20230183216A1
(en)
|
2021-10-28 |
2023-06-15 |
Gilead Sciences, Inc. |
Pyridizin-3(2h)-one derivatives
|
|
EP4422756A1
(en)
|
2021-10-29 |
2024-09-04 |
Gilead Sciences, Inc. |
Cd73 compounds
|
|
US12187744B2
(en)
|
2021-10-29 |
2025-01-07 |
Kymera Therapeutics, Inc. |
IRAK4 degraders and synthesis thereof
|
|
WO2023081735A1
(en)
|
2021-11-03 |
2023-05-11 |
Celgene Corporation |
Chimeric antigen receptors specific for b-cell maturation antigen for use in treating myeloma
|
|
US20260083848A1
(en)
|
2021-11-03 |
2026-03-26 |
Viracta Therapeutics, Inc. |
Combination of car t-cell therapy with btk inhibitors and methods of use thereof
|
|
US20250000906A1
(en)
|
2021-11-16 |
2025-01-02 |
Sotio Biotech Inc. |
Treatment of myxoid/round cell liposarcoma patients
|
|
WO2023092119A2
(en)
|
2021-11-22 |
2023-05-25 |
Ludwig Institute For Cancer Research Ltd |
Methods for predicting responsiveness to a cancer therapy
|
|
US20250354167A1
(en)
|
2021-12-09 |
2025-11-20 |
Zygosity Limited |
Vector
|
|
US20250059239A1
(en)
|
2021-12-17 |
2025-02-20 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae fusion glycoproteins
|
|
EP4448775A1
(en)
|
2021-12-17 |
2024-10-23 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae attachment glycoproteins
|
|
WO2023114984A1
(en)
|
2021-12-17 |
2023-06-22 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
KR102809807B1
(ko)
*
|
2021-12-21 |
2025-05-16 |
한림대학교 산학협력단 |
항-cldn18.2를 포함하는 키메릭 항원 수용체를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 및 이의 제조 방법
|
|
CN118488946A
(zh)
|
2021-12-22 |
2024-08-13 |
吉利德科学公司 |
Ikaros锌指家族降解剂及其用途
|
|
EP4452415B1
(en)
|
2021-12-22 |
2026-02-25 |
Gilead Sciences, Inc. |
Ikaros zinc finger family degraders and uses thereof
|
|
MX2024007528A
(es)
|
2021-12-23 |
2024-08-30 |
Sana Biotechnology Inc |
Linfocitos t del receptor de antígeno quimérico (car) para el tratamiento de enfermedades autoinmunitarias y métodos asociados.
|
|
EP4456910A1
(en)
|
2021-12-28 |
2024-11-06 |
Mnemo Therapeutics |
Immune cells with inactivated suv39h1 and modified tcr
|
|
TW202334400A
(zh)
|
2021-12-30 |
2023-09-01 |
美商Tr1X股份有限公司 |
表現il-10及嵌合抗原受體之cd4+ t細胞及其用途
|
|
WO2023133595A2
(en)
|
2022-01-10 |
2023-07-13 |
Sana Biotechnology, Inc. |
Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
|
|
TW202340474A
(zh)
|
2022-01-11 |
2023-10-16 |
大陸商深圳市珈鈺生物科技有限公司 |
樹突細胞腫瘤疫苗和其用途
|
|
WO2023137472A2
(en)
|
2022-01-14 |
2023-07-20 |
Tune Therapeutics, Inc. |
Compositions, systems, and methods for programming t cell phenotypes through targeted gene repression
|
|
US20250134999A1
(en)
|
2022-01-14 |
2025-05-01 |
Tune Therapeutics, Inc. |
Compositions, systems, and methods for programming t cell phenotypes through targeted gene activation
|
|
EP4215245A1
(en)
|
2022-01-19 |
2023-07-26 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Enhanced chimeric antigen receptor cells in hypoxic tumor microenvironment
|
|
US20250115916A1
(en)
|
2022-01-21 |
2025-04-10 |
Mnemo Therapeutics |
Modulation of suv39h1 expression by rnas
|
|
TW202340168A
(zh)
|
2022-01-28 |
2023-10-16 |
美商基利科學股份有限公司 |
Parp7抑制劑
|
|
JP2025504002A
(ja)
|
2022-01-28 |
2025-02-06 |
ジュノー セラピューティクス インコーポレイテッド |
細胞組成物を製造する方法
|
|
EP4472967A4
(en)
|
2022-01-31 |
2026-04-15 |
Kymera Therapeutics Inc |
Iraqi Degradation Agents and Their Uses
|
|
EP4472646A1
(en)
|
2022-02-01 |
2024-12-11 |
Sana Biotechnology, Inc. |
Cd3-targeted lentiviral vectors and uses thereof
|
|
WO2023150181A1
(en)
|
2022-02-01 |
2023-08-10 |
President And Fellows Of Harvard College |
Methods and compositions for treating cancer
|
|
US20250144235A1
(en)
|
2022-02-02 |
2025-05-08 |
Sana Biotechnology, Inc. |
Methods of repeat dosing and administration of lipid particles or viral vectors and related systems and uses
|
|
JP2025508371A
(ja)
*
|
2022-02-11 |
2025-03-26 |
フレッド ハッチンソン キャンサー センター |
Steap1に結合するキメラ抗原受容体
|
|
WO2023154578A1
(en)
|
2022-02-14 |
2023-08-17 |
Sana Biotechnology, Inc. |
Methods of treating patients exhibiting a prior failed therapy with hypoimmunogenic cells
|
|
US20230296610A1
(en)
|
2022-02-15 |
2023-09-21 |
Kite Pharma, Inc. |
Predicting adverse events from immunotherapy
|
|
KR20240155390A
(ko)
|
2022-02-17 |
2024-10-28 |
사나 바이오테크놀로지, 인크. |
조작된 cd47 단백질 및 이의 용도
|
|
IL314801A
(en)
|
2022-02-22 |
2024-10-01 |
Juno Therapeutics Inc |
Proteinase 3 (PR3) Chimeric Autoantigen Receptor T Cells and Related Methods and Uses
|
|
TW202340457A
(zh)
|
2022-02-28 |
2023-10-16 |
美商凱特製藥公司 |
同種異體治療細胞
|
|
EP4486881A1
(en)
|
2022-03-01 |
2025-01-08 |
Celyntra Therapeutics SA |
Composition and methods for transgene insertion
|
|
WO2023172883A1
(en)
|
2022-03-07 |
2023-09-14 |
Alpine Immune Sciences, Inc. |
Immunomodulatory proteins of variant cd80 polypeptides, cell therapies thereof and related methods and uses
|
|
CN119156403A
(zh)
|
2022-03-08 |
2024-12-17 |
阿伦蒂斯治疗股份公司 |
抗紧密连接蛋白-1抗体增加t细胞可用性的用途
|
|
WO2023173057A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
WO2023173053A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
US20250101382A1
(en)
|
2022-03-11 |
2025-03-27 |
Sana Biotechnology, Inc. |
Genetically modified cells and compositions and uses thereof
|
|
WO2023173137A1
(en)
|
2022-03-11 |
2023-09-14 |
Yale University |
Compositions and methods for efficient and stable genetic modification of eukaryotic cells
|
|
CA3253296A1
(en)
|
2022-03-17 |
2023-09-21 |
Gilead Sciences, Inc. |
Zinc Finger Degradation Agents of the Ikaros Family and Their Uses
|
|
US20250195573A1
(en)
|
2022-03-18 |
2025-06-19 |
The Regents Of The University Of Colorado, A Body Corporate |
Genetically engineered t-cell co-receptors and methods of use thereof
|
|
AU2023240346A1
(en)
|
2022-03-24 |
2024-09-19 |
Gilead Sciences, Inc. |
Combination therapy for treating trop-2 expressing cancers
|
|
JP2025510795A
(ja)
|
2022-03-24 |
2025-04-15 |
アンスティテュ・クリー |
神経膠芽腫における腫瘍転位因子由来のネオ抗原ペプチドを標的化する免疫療法
|
|
GB202204386D0
(en)
|
2022-03-28 |
2022-05-11 |
Cambridge Entpr Ltd |
Engineered immune cell platform
|
|
US20250222027A1
(en)
|
2022-04-01 |
2025-07-10 |
Sana Biotechnology, Inc. |
Cytokine receptor agonist and viral vector combination therapies
|
|
TWI876305B
(zh)
|
2022-04-05 |
2025-03-11 |
美商基利科學股份有限公司 |
用於治療結腸直腸癌之組合療法
|
|
WO2023196921A1
(en)
|
2022-04-06 |
2023-10-12 |
The Regents Of The University Of Colorado, A Body Corporate |
Granzyme expressing t cells and methods of use
|
|
WO2023196933A1
(en)
|
2022-04-06 |
2023-10-12 |
The Regents Of The University Of Colorado, A Body Corporate |
Chimeric antigen receptor t cells and methods of use thereof
|
|
WO2023205719A1
(en)
|
2022-04-21 |
2023-10-26 |
Gilead Sciences, Inc. |
Kras g12d modulating compounds
|
|
WO2023211889A1
(en)
|
2022-04-25 |
2023-11-02 |
Ikena Oncology, Inc. |
Polymorphic compounds and uses thereof
|
|
EP4514382A1
(en)
|
2022-04-28 |
2025-03-05 |
Musc Foundation for Research Development |
Chimeric antigen receptor modified regulatory t cells for treating cancer
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
WO2023213969A1
(en)
|
2022-05-05 |
2023-11-09 |
Juno Therapeutics Gmbh |
Viral-binding protein and related reagents, articles, and methods of use
|
|
US20250161360A1
(en)
|
2022-05-10 |
2025-05-22 |
Yale University |
Compositions and methods of synthetic ctla-4 tails for reprogramming of car-t cells and enhancement of anti-tumor efficacy
|
|
US20250295771A1
(en)
|
2022-05-11 |
2025-09-25 |
Celgene Corporation |
Methods and uses related to t cell therapy and production of same
|
|
WO2023220655A1
(en)
|
2022-05-11 |
2023-11-16 |
Celgene Corporation |
Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
|
|
EP4279085A1
(en)
|
2022-05-20 |
2023-11-22 |
Mnemo Therapeutics |
Compositions and methods for treating a refractory or relapsed cancer or a chronic infectious disease
|
|
IL316768A
(en)
|
2022-05-25 |
2025-01-01 |
Ikena Oncology Inc |
MEK inhibitors and their uses
|
|
EP4532695A1
(en)
|
2022-05-25 |
2025-04-09 |
Celgene Corporation |
Methods of manufacturing t cell therapies
|
|
WO2023230548A1
(en)
|
2022-05-25 |
2023-11-30 |
Celgene Corporation |
Method for predicting response to a t cell therapy
|
|
WO2023230276A1
(en)
|
2022-05-27 |
2023-11-30 |
Kite Pharma, Inc. |
Compositions and methods for preparing engineered lymphocytes for cell therapy
|
|
CA3253031A1
(en)
|
2022-05-27 |
2023-11-30 |
Kite Pharma, Inc. |
NON-VIRAL ADMINISTRATION OF CELL THERAPY CONSTRUCTIONS
|
|
AU2023282907A1
(en)
|
2022-06-09 |
2024-11-14 |
Kite Pharma, Inc. |
Methods of preparing lymphocytes for cell therapy
|
|
WO2023239940A1
(en)
|
2022-06-10 |
2023-12-14 |
Research Development Foundation |
Engineered fcriib selective igg1 fc variants and uses thereof
|
|
WO2023242343A1
(en)
|
2022-06-15 |
2023-12-21 |
Immunoscape Pte. Ltd. |
Human t cell receptors specific for antigenic peptides derived from mitogen-activated protein kinase 8 interacting protein 2 (mapk8ip2), epstein-barr virus or human endogenous retrovirus, and uses thereof
|
|
EP4543923A1
(en)
|
2022-06-22 |
2025-04-30 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
|
US20250382640A1
(en)
|
2022-06-29 |
2025-12-18 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids
|
|
GB202209518D0
(en)
|
2022-06-29 |
2022-08-10 |
Snipr Biome Aps |
Treating & preventing E coli infections
|
|
CN120051297A
(zh)
|
2022-06-30 |
2025-05-27 |
因达普塔治疗公司 |
工程化自然杀伤(nk)细胞与抗体疗法的组合及相关方法
|
|
US20240116928A1
(en)
|
2022-07-01 |
2024-04-11 |
Gilead Sciences, Inc. |
Cd73 compounds
|
|
WO2024026377A1
(en)
|
2022-07-27 |
2024-02-01 |
Sana Biotechnology, Inc. |
Methods of transduction using a viral vector and inhibitors of antiviral restriction factors
|
|
AU2023314413A1
(en)
|
2022-07-28 |
2025-02-13 |
Lentigen Technology, Inc. |
Chimeric antigen receptor therapies for treating solid tumors
|
|
IL318575A
(en)
|
2022-08-02 |
2025-03-01 |
Liminal Biosciences Ltd |
HETEROARYL CARBOXAMIDE AND GPR84-RELATED ANTAGONISTS AND USES THEREOF
|
|
US20260041767A1
(en)
|
2022-08-02 |
2026-02-12 |
National University Corporation Hokkaido University |
Methods of improving cellular therapy with organelle complexes
|
|
JP2025527247A
(ja)
|
2022-08-02 |
2025-08-20 |
リミナル・バイオサイエンシーズ・リミテッド |
アリール-トリアゾリル及び関連するgpr84アンタゴニストならびにそれらの使用
|
|
CN120051456A
(zh)
|
2022-08-02 |
2025-05-27 |
里米诺生物科学有限公司 |
取代的吡啶酮gpr84拮抗剂及其用途
|
|
JP2025526690A
(ja)
|
2022-08-10 |
2025-08-15 |
武田薬品工業株式会社 |
免疫原性が低い改変細胞
|
|
US20260053924A1
(en)
|
2022-08-19 |
2026-02-26 |
Sotio Biotech Inc. |
Genetically engineered immune cells with chimeric receptor polypeptides in combination with multiple trans metabolism molecules and therapeutic uses thereof
|
|
WO2024040207A1
(en)
|
2022-08-19 |
2024-02-22 |
Sotio Biotech Inc. |
Genetically engineered natural killer (nk) cells with chimeric receptor polypeptides in combination with trans metabolism molecules and therapeutic uses thereof
|
|
CA3264572A1
(en)
|
2022-08-26 |
2024-02-29 |
Juno Therapeutics, Inc. |
DELTA-TYPE CHIMERICAL ANTIBODIES AND ANTIGENIC RECEPTORS (DLL3)
|
|
US20240091261A1
(en)
|
2022-08-26 |
2024-03-21 |
Kite Pharma, Inc. |
Immune cell function
|
|
CN120152717A
(zh)
|
2022-09-08 |
2025-06-13 |
朱诺治疗学股份有限公司 |
T细胞疗法和连续或间歇dgk抑制剂给药的组合
|
|
EP4587047A1
(en)
|
2022-09-15 |
2025-07-23 |
Novartis AG |
Treatment of autoimmune disorders using chimeric antigen receptor therapy
|
|
CN120239746A
(zh)
|
2022-09-19 |
2025-07-01 |
图恩疗法股份有限公司 |
用于调节t细胞功能的组合物、系统和方法
|
|
CN116063560A
(zh)
*
|
2022-09-21 |
2023-05-05 |
东莞市东南部中心医院 |
一种sh Blimp-1 CAR-T细胞的构建及应用
|
|
WO2024064668A1
(en)
|
2022-09-21 |
2024-03-28 |
Gilead Sciences, Inc. |
FOCAL IONIZING RADIATION AND CD47/SIRPα DISRUPTION ANTICANCER COMBINATION THERAPY
|
|
WO2024064824A2
(en)
|
2022-09-21 |
2024-03-28 |
Yale University |
Compositions and methods for identification of membrane targets for enhancement of nk cell therapy
|
|
WO2024062138A1
(en)
|
2022-09-23 |
2024-03-28 |
Mnemo Therapeutics |
Immune cells comprising a modified suv39h1 gene
|
|
EP4593871A1
(en)
|
2022-09-30 |
2025-08-06 |
Caribou Biosciences, Inc. |
Anti-ror1 chimeric antigen receptors (cars), car-nk cells and related methods
|
|
WO2024077256A1
(en)
|
2022-10-07 |
2024-04-11 |
The General Hospital Corporation |
Methods and compositions for high-throughput discovery ofpeptide-mhc targeting binding proteins
|
|
WO2024081820A1
(en)
|
2022-10-13 |
2024-04-18 |
Sana Biotechnology, Inc. |
Viral particles targeting hematopoietic stem cells
|
|
US20240226210A9
(en)
*
|
2022-10-24 |
2024-07-11 |
Broaden Bioscience And Technology Corp |
Oncolytic virus combined with car t cells for anti-tumor therapy
|
|
CN120112650A
(zh)
|
2022-10-26 |
2025-06-06 |
诺华股份有限公司 |
慢病毒配制品
|
|
WO2024092227A1
(en)
|
2022-10-28 |
2024-05-02 |
Kite Pharma, Inc. |
Factors for optimizing immunotherapy
|
|
WO2024091669A1
(en)
|
2022-10-28 |
2024-05-02 |
Ginkgo Bioworks, Inc. |
Chimeric antigen receptors comprising an intracellular domain pair
|
|
KR20250097844A
(ko)
|
2022-10-28 |
2025-06-30 |
카이트 파마 인코포레이티드 |
면역요법의 효능 향상 및 지속적인 반응
|
|
CN120051287A
(zh)
|
2022-10-28 |
2025-05-27 |
凯德药业股份有限公司 |
工程化淋巴细胞的加速施用
|
|
WO2024097315A2
(en)
|
2022-11-02 |
2024-05-10 |
Sana Biotechnology, Inc. |
Cell therapy products and methods for producing same
|
|
WO2024097905A1
(en)
|
2022-11-02 |
2024-05-10 |
Celgene Corporation |
Methods of treatment with t cell therapy and immunomodulatory agent maintenance therapy
|
|
WO2024098024A1
(en)
|
2022-11-04 |
2024-05-10 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
|
EP4615960A1
(en)
|
2022-11-09 |
2025-09-17 |
C3S2 GmbH |
Methods for manufacturing engineered immune cells
|
|
WO2024102948A1
(en)
|
2022-11-11 |
2024-05-16 |
Celgene Corporation |
Fc receptor-homolog 5 (fcrh5) specific binding molecules and bispecific t-cell engaging antibodies including same and related methods
|
|
EP4584283A1
(en)
|
2022-11-14 |
2025-07-16 |
Caribou Biosciences, Inc. |
Anti-cll-1 chimeric antigen receptors, engineered cells and related methods
|
|
CN120548323A
(zh)
|
2022-11-18 |
2025-08-26 |
首尔国立大学校产学协力团 |
利用ctla-4变体及嵌合抗原受体的双基因转导免疫细胞及其用途
|
|
US20240208961A1
(en)
|
2022-11-22 |
2024-06-27 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
|
TW202440623A
(zh)
|
2022-11-28 |
2024-10-16 |
美商艾洛基因醫療公司 |
靶向密連蛋白18﹒2之嵌合抗原受體及結合劑以及其用途
|
|
KR20250114116A
(ko)
|
2022-12-01 |
2025-07-28 |
제너레이션 바이오 컴퍼니 |
세포 표적화를 위한 스텔스 지질 나노입자 조성물
|
|
WO2024124044A1
(en)
|
2022-12-07 |
2024-06-13 |
The Brigham And Women’S Hospital, Inc. |
Compositions and methods targeting sat1 for enhancing anti¬ tumor immunity during tumor progression
|
|
CN121100267A
(zh)
|
2022-12-09 |
2025-12-09 |
朱诺治疗学股份有限公司 |
使用全息成像预测细胞表型的机器学习方法
|
|
CN120712102A
(zh)
|
2022-12-13 |
2025-09-26 |
朱诺治疗学股份有限公司 |
对baff-r和cd19具特异性的嵌合抗原受体及其方法和用途
|
|
EP4638436A1
(en)
|
2022-12-22 |
2025-10-29 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|
|
WO2024151541A1
(en)
|
2023-01-09 |
2024-07-18 |
Sana Biotechnology, Inc. |
Type-1 diabetes autoimmune mouse
|
|
WO2024155821A1
(en)
|
2023-01-18 |
2024-07-25 |
Yale University |
Chimeric antigen receptors (car) with intrinsically disordered regions and methods of use thereof
|
|
CN121002052A
(zh)
|
2023-02-03 |
2025-11-21 |
C3S2 有限公司 |
用于非病毒生产工程化免疫细胞的方法
|
|
WO2024178128A1
(en)
*
|
2023-02-22 |
2024-08-29 |
Elysion Therapeutics, Inc. |
Lysis sensing receptors and uses thereof
|
|
WO2024178397A2
(en)
|
2023-02-24 |
2024-08-29 |
Elevatebio Technologies, Inc. |
Modified immune effector cells and methods of use
|
|
KR20260005874A
(ko)
|
2023-02-28 |
2026-01-12 |
주노 쎄러퓨티크스 인코퍼레이티드 |
전신 자가면역 질환을 치료하기 위한 세포 요법
|
|
WO2024182539A1
(en)
|
2023-02-28 |
2024-09-06 |
Lyell Immunopharma, Inc. |
Methods of culturing reprogrammed cells
|
|
KR20250158048A
(ko)
|
2023-03-03 |
2025-11-05 |
아스널 바이오사이언시스, 인크. |
Psma 및 ca9을 표적으로 하는 시스템
|
|
AU2024233069A1
(en)
|
2023-03-09 |
2025-09-11 |
Kite Pharma, Inc. |
Antigen binding molecules and methods of use
|
|
PE20252678A1
(es)
|
2023-03-13 |
2025-11-24 |
Arsenal Biosciences Inc |
Activadores de vias sinteticas
|
|
KR20250162836A
(ko)
|
2023-03-17 |
2025-11-19 |
카이트 파마 인코포레이티드 |
종양 미세환경이 면역요법의 효능에 미치는 영향
|
|
CN121605309A
(zh)
|
2023-03-23 |
2026-03-03 |
阿伦蒂斯治疗股份公司 |
使用抗紧密连接蛋白-1抗体的癌症治疗的生物标志物
|
|
WO2024206155A1
(en)
|
2023-03-24 |
2024-10-03 |
Cornell University |
Utilizing t cells derived from tumor draining lymph nodes for chimeric antigen receptor (car) t cell therapy for the treatment of cancer
|
|
CA3278900A1
(en)
|
2023-03-31 |
2024-10-03 |
AbelZeta Inc. |
BISPECIFIC CHIMERIC ANTIGENIC RECEPTORS TARGETING CD20 AND BCMA
|
|
WO2024211852A1
(en)
*
|
2023-04-07 |
2024-10-10 |
Fate Therapeutics, Inc. |
Ipsc-derived nk cell for lymphoma treatment
|
|
KR20250169609A
(ko)
|
2023-04-07 |
2025-12-03 |
리제너론 파마슈티칼스 인코포레이티드 |
림포톡신 β 수용체 작용제를 이용한 암 치료 방법
|
|
CN120882725A
(zh)
|
2023-04-11 |
2025-10-31 |
吉利德科学公司 |
Kras调节化合物
|
|
EP4694916A1
(en)
|
2023-04-14 |
2026-02-18 |
SOTIO Biotech Inc. |
Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists
|
|
WO2024215987A1
(en)
|
2023-04-14 |
2024-10-17 |
Sotio Biotech Inc. |
IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES
|
|
WO2024220597A2
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Digital droplet based assay for detecting replication competent lentiviral vector
|
|
EP4698665A1
(en)
|
2023-04-18 |
2026-02-25 |
Sana Biotechnology, Inc. |
Engineered protein g fusogens and related lipid particles and methods thereof
|
|
KR20250169631A
(ko)
|
2023-04-18 |
2025-12-03 |
주노 쎄러퓨티크스 인코퍼레이티드 |
치료 세포 조성물의 효력을 평가하기 위한 세포독성 검정
|
|
EP4698666A1
(en)
|
2023-04-18 |
2026-02-25 |
Sana Biotechnology, Inc. |
Universal protein g fusogens and adapter systems thereof and related lipid particles and uses
|
|
WO2024220598A2
(en)
|
2023-04-18 |
2024-10-24 |
Sana Biotechnology, Inc. |
Lentiviral vectors with two or more genomes
|
|
WO2024220619A1
(en)
|
2023-04-21 |
2024-10-24 |
Kite Pharma, Inc. |
Allogenic therapeutic cells with reduced risk of immune rejection
|
|
WO2024220917A1
(en)
|
2023-04-21 |
2024-10-24 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|
|
CN121038806A
(zh)
|
2023-04-25 |
2025-11-28 |
阿森纳生物科学公司 |
用于转录调控的新颖受体
|
|
WO2024226829A2
(en)
|
2023-04-26 |
2024-10-31 |
Yale University |
Enpp3-binding molecules, compositions formed therefrom, and methods of use thereof for the treatment of cancer
|
|
WO2024226858A1
(en)
|
2023-04-26 |
2024-10-31 |
Juno Therapeutics, Inc. |
Methods for viral vector manufacturing
|
|
TW202506996A
(zh)
|
2023-04-27 |
2025-02-16 |
日商武田藥品工業股份有限公司 |
擴增cd56+/cd3-細胞之方法
|
|
EP4703374A1
(en)
|
2023-04-28 |
2026-03-04 |
Shenzhen Shenxin Biotechnology Co., Ltd. |
Modified delivery vector and use thereof
|
|
WO2024229302A1
(en)
|
2023-05-03 |
2024-11-07 |
Sana Biotechnology, Inc. |
Methods of dosing and administration of engineered islet cells
|
|
AU2024267555A1
(en)
|
2023-05-11 |
2025-11-20 |
Alaya.Bio Inc. |
Extracellular vesicles for the delivery of payloads to eukaryotic cells
|
|
EP4713352A1
(en)
|
2023-05-15 |
2026-03-25 |
Yale University |
Chimeric antigen receptor compositions, car-mast cells formed therefrom, and methods of use thereof
|
|
EP4713464A1
(en)
*
|
2023-05-17 |
2026-03-25 |
Mayo Foundation for Medical Education and Research |
Materials and methods for increasing immune responses within a mammal
|
|
WO2024236547A1
(en)
|
2023-05-18 |
2024-11-21 |
Inceptor Bio, Llc |
Modified phagocytic cells expressing chimeric antigen receptors comprising a herpes virus entry mediator (hvem) co-stimulatory domain and uses thereof
|
|
EP4714977A1
(en)
|
2023-05-19 |
2026-03-25 |
Seoul National University R&DB Foundation |
Use of anti-cd3 antibody for selectively depleting activated t cells
|
|
CN121604968A
(zh)
|
2023-05-22 |
2026-03-03 |
萨那生物科技公司 |
递送胰岛细胞的方法及相关方法
|
|
CN121464348A
(zh)
|
2023-05-23 |
2026-02-03 |
朱诺治疗学股份有限公司 |
T细胞的激活标记物和评估t细胞激活的方法
|
|
CN120981456A
(zh)
|
2023-05-24 |
2025-11-18 |
金橘生物科技公司 |
杂环化合物及其用途
|
|
WO2024243514A1
(en)
*
|
2023-05-25 |
2024-11-28 |
Trustees Of Dartmouth College |
Leveraging photothermal heating for surface processing of active agents
|
|
CN121335919A
(zh)
|
2023-05-25 |
2026-01-13 |
瑞泽恩制药公司 |
结合呈递的hpv16、mart1、cmv、ebv或流感肽的t细胞受体
|
|
US12531162B1
(en)
*
|
2023-05-31 |
2026-01-20 |
Northeastern University |
Multi-dimensional phenotypic space for genotype to phenotype mapping and intelligent design of cancer drug therapies using a deep learning net
|
|
EP4720316A2
(en)
|
2023-06-14 |
2026-04-08 |
Arsenal Biosciences, Inc. |
Non-viral cell engineering
|
|
IL321486A
(en)
|
2023-06-23 |
2025-08-01 |
Kymera Therapeutics Inc |
Iraqi joints and their uses
|
|
CN121712794A
(zh)
|
2023-06-29 |
2026-03-20 |
迪斯派奇生物治疗公司 |
合成细胞因子受体
|
|
US20250042922A1
(en)
|
2023-06-30 |
2025-02-06 |
Gilead Sciences, Inc. |
Kras modulating compounds
|
|
US12319747B2
(en)
|
2023-07-03 |
2025-06-03 |
Medicovestor, Inc. |
Methods of using anti-SP17 immunotherapeutics
|
|
WO2025014896A1
(en)
|
2023-07-07 |
2025-01-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Humanized 40h3 antibody
|
|
US20250066328A1
(en)
|
2023-07-26 |
2025-02-27 |
Gilead Sciences, Inc. |
Parp7 inhibitors
|
|
AU2024297978A1
(en)
|
2023-07-26 |
2026-02-05 |
Gilead Sciences, Inc. |
Parp7 inhibitors
|
|
WO2025029840A1
(en)
|
2023-07-31 |
2025-02-06 |
Tune Therapeutics, Inc. |
Compositions and methods for multiplexed activation and repression of t cell gene expression
|
|
CN121909284A
(zh)
|
2023-07-31 |
2026-04-21 |
图恩疗法股份有限公司 |
用于调节il-2基因表达的组合物和方法
|
|
WO2025030010A1
(en)
|
2023-08-01 |
2025-02-06 |
Vor Biopharma Inc. |
Compositions comprising genetically engineered hematopoietic stem cells and methods of use thereof
|
|
WO2025038750A2
(en)
|
2023-08-14 |
2025-02-20 |
President And Fellows Of Harvard College |
Methods and compositions for treating cancer
|
|
AU2024328949A1
(en)
|
2023-08-23 |
2026-03-12 |
Sana Biotechnology, Inc. |
Modified cd47 proteins and their uses
|
|
WO2025051339A1
(en)
|
2023-09-05 |
2025-03-13 |
Tiber Biotech Srl |
SINGLE-CHAIN VARIABLE FRAGMENT AND MOLECULES DERIVING THEREFROM THAT BIND FRAGMENT TRVB5-1 OF THE β CHAIN OF HUMAN T-CELL RECEPTOR
|
|
WO2025054202A1
(en)
|
2023-09-05 |
2025-03-13 |
Sana Biotechnology, Inc. |
Method of screening a sample comprising a transgene with a unique barcode
|
|
EP4520334A1
(en)
|
2023-09-07 |
2025-03-12 |
Mnemo Therapeutics |
Methods and compositions for improving immune response
|
|
WO2025052001A1
(en)
|
2023-09-07 |
2025-03-13 |
Mnemo Therapeutics |
Methods and compositions for improving immune response
|
|
WO2025054347A1
(en)
|
2023-09-08 |
2025-03-13 |
Gilead Sciences, Inc. |
Kras g12d modulating compounds
|
|
WO2025059533A1
(en)
|
2023-09-13 |
2025-03-20 |
The Broad Institute, Inc. |
Crispr enzymes and systems
|
|
WO2025059414A1
(en)
*
|
2023-09-15 |
2025-03-20 |
Singular Immune, Inc. |
Composition and method of use recombinant fusion protein to generate car-immune cells
|
|
CN121889164A
(zh)
|
2023-09-26 |
2026-04-17 |
阿斯利康(瑞典)有限公司 |
包含抗steap2嵌合抗原受体t细胞的治疗组合
|
|
WO2025072571A1
(en)
|
2023-09-27 |
2025-04-03 |
Cellanome, Inc. |
Cell culture within microfluidic structures
|
|
WO2025076127A1
(en)
|
2023-10-05 |
2025-04-10 |
Capstan Therapeutics, Inc. |
Constrained ionizable cationic lipids and lipid nanoparticles
|
|
WO2025076113A1
(en)
|
2023-10-05 |
2025-04-10 |
Capstan Therapeutics, Inc. |
Ionizable cationic lipids with conserved spacing and lipid nanoparticles
|
|
WO2025083398A1
(en)
|
2023-10-16 |
2025-04-24 |
Cell Therapy Catapult Limited |
Co-culture
|
|
WO2025082603A1
(en)
|
2023-10-18 |
2025-04-24 |
Institut Curie |
Engineered immune cells overexpressing cd74 molecule
|
|
US12364777B2
(en)
|
2023-10-20 |
2025-07-22 |
Medicovestor, Inc. |
Homodimeric antibodies for use in treating cancers and methods of use
|
|
WO2025090985A1
(en)
*
|
2023-10-27 |
2025-05-01 |
Duke University |
Compositions comprising chimeric antigen receptors targeting citrullinated vimentin and methods of use thereof
|
|
WO2025096305A1
(en)
*
|
2023-10-30 |
2025-05-08 |
The Cleveland Clinic Foundation |
Chimeric antigen receptors with a tip co-stimulatory domain
|
|
AU2024369584A1
(en)
|
2023-10-30 |
2026-04-09 |
Allogene Therapeutics, Inc. |
Cells expressing anti-cd19 chimeric antigen receptors and methods of use thereof
|
|
WO2025096419A1
(en)
|
2023-10-31 |
2025-05-08 |
Lyell Immunopharma, Inc. |
T cells comprising a chimeric antigen receptor targeting transforming growth factor beta and a t cell receptor targeting a tumor antigen, and use thereof
|
|
WO2025096517A1
(en)
|
2023-11-01 |
2025-05-08 |
Kite Pharma, Inc. |
Factors for optimizing immunotherapy efficacy
|
|
WO2025097055A2
(en)
|
2023-11-02 |
2025-05-08 |
The Broad Institute, Inc. |
Compositions and methods of use of t cells in immunotherapy
|
|
WO2025096975A1
(en)
|
2023-11-02 |
2025-05-08 |
The Regents Of The University Of Colorado, A Body Corporate |
Compositions and methods of enhancing immune cell therapies by runx2 modulation
|
|
US20250154172A1
(en)
|
2023-11-03 |
2025-05-15 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|
|
US12562256B2
(en)
*
|
2023-11-07 |
2026-02-24 |
New York University |
Systems, methods and computer-accessible medium for identifying target pairs for CAR-T therapy
|
|
WO2025117544A1
(en)
|
2023-11-29 |
2025-06-05 |
The Broad Institute, Inc. |
Engineered omega guide molecule and iscb compositions, systems, and methods of use thereof
|
|
WO2025128434A1
(en)
|
2023-12-14 |
2025-06-19 |
The Regents Of The University Of Colorado, A Body Corporate |
Compositions and methods for the treatment of ven/aza resistant acute myeloid leukemia
|
|
WO2025129120A2
(en)
|
2023-12-15 |
2025-06-19 |
Port Therapeutics, Inc. |
Use of thermal bioswitches for treating autoimmune diseases
|
|
TW202526007A
(zh)
|
2023-12-21 |
2025-07-01 |
美商凱特製藥公司 |
用於上調低密度脂蛋白受體(ldl-r)表現之系統及方法
|
|
WO2025137640A1
(en)
|
2023-12-22 |
2025-06-26 |
Gilead Sciences, Inc. |
Azaspiro wrn inhibitors
|
|
US12600795B2
(en)
|
2023-12-26 |
2026-04-14 |
Medicovestor, Inc. |
Oligomeric IgG for immunotherapeutics and diagnostics
|
|
US12116410B1
(en)
|
2023-12-26 |
2024-10-15 |
Medicovestor, Inc. |
Methods of manufacturing dimeric antibodies
|
|
WO2025147545A1
(en)
|
2024-01-03 |
2025-07-10 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids and related methods and uses
|
|
WO2025146286A1
(en)
|
2024-01-04 |
2025-07-10 |
Immunoscape Pte. Ltd. |
Human t cell receptors and uses thereof
|
|
WO2025151838A1
(en)
|
2024-01-12 |
2025-07-17 |
Sana Biotechnology, Inc. |
Safety switches to control in vitro and in vivo proliferation of cell therapy products
|
|
WO2025151923A1
(en)
*
|
2024-01-17 |
2025-07-24 |
Newsouth Innovations Pty Limited |
Apparatus for production of engineered cells
|
|
WO2025158400A1
(en)
|
2024-01-24 |
2025-07-31 |
Yale University |
Compositions and methods of natural killer cell hyperboosts for enhancement of nk cell therapy
|
|
WO2025163107A1
(en)
|
2024-02-01 |
2025-08-07 |
Institut Gustave Roussy |
Immune cells defective for znf217 and uses thereof
|
|
US12240900B1
(en)
|
2024-02-02 |
2025-03-04 |
Medicovestor, Inc. |
Nucleic acids, vectors, and cells that encode antibodies and other proteins that bind folate receptor alpha
|
|
US12378314B1
(en)
|
2024-02-02 |
2025-08-05 |
Medicovestor, Inc. |
Proteins that bind folate receptor alpha including fully-human antibodies
|
|
US12258396B1
(en)
|
2024-02-02 |
2025-03-25 |
Medicovestor, Inc. |
Methods of using immunotherapeutics that bind folate receptor alpha
|
|
US20250297219A1
(en)
|
2024-02-08 |
2025-09-25 |
Kite Pharma, Inc. |
Methods for generating engineered lymphocytes with enriched t memory stem cells
|
|
US20250262300A1
(en)
|
2024-02-16 |
2025-08-21 |
Kite Pharma, Inc. |
Systems, methods, and kits for generating and administering engineered t cells and cd38 targeting compounds as a combination therapy
|
|
WO2025184421A1
(en)
|
2024-02-28 |
2025-09-04 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors and antibodies specific for delta-like ligand 3 (dll3) and related methods
|
|
WO2025181329A1
(en)
|
2024-03-01 |
2025-09-04 |
Immunoscape Pte. Ltd. |
Human t cell receptors and uses thereof
|
|
WO2025188561A1
(en)
|
2024-03-04 |
2025-09-12 |
Kite Pharma, Inc. |
Predictive markers for immunotherapy
|
|
WO2025191300A1
(en)
|
2024-03-12 |
2025-09-18 |
Novartis Ag |
Rapcabtagene autoleucel for use in treating systemic lupus erythematosus
|
|
US20250361297A1
(en)
|
2024-03-12 |
2025-11-27 |
Adaptam Therapeutics, S.L. |
Anti- siglec-15 binding molecules and methods of use
|
|
WO2025191531A1
(en)
|
2024-03-15 |
2025-09-18 |
Takeda Pharmaceutical Company Limited |
Cd19 targeting car nk cells in treating systemic lupus erythematosus and lupus nephritis
|
|
WO2025199338A1
(en)
|
2024-03-20 |
2025-09-25 |
Arsenal Biosciences, Inc. |
Systems targeting slc34a2 and tmprss4 and methods of use thereof
|
|
WO2025199346A1
(en)
|
2024-03-20 |
2025-09-25 |
Arsenal Biosciences, Inc. |
Antigen binding proteins that bind tmprss4 and methods of use thereof
|
|
EP4624494A1
(en)
|
2024-03-29 |
2025-10-01 |
Institut Curie |
Her2 single domain antibody and uses thereof
|
|
WO2025217452A1
(en)
|
2024-04-11 |
2025-10-16 |
Capstan Therapeutics, Inc. |
Constrained ionizable cationic lipids and lipid nanoparticles
|
|
WO2025217454A2
(en)
|
2024-04-11 |
2025-10-16 |
Capstan Therapeutics, Inc. |
Ionizable cationic lipids and lipid nanoparticles
|
|
WO2025231376A1
(en)
|
2024-05-03 |
2025-11-06 |
Kite Pharma, Inc. |
Chimeric receptors binding to cll-1 and methods of use thereof
|
|
US20250345431A1
(en)
|
2024-05-10 |
2025-11-13 |
Juno Therapeutics, Inc. |
Genetically engineered t cells expressing a cd19 chimeric antigen receptor (car) and uses thereof for allogeneic cell therapy
|
|
US20250376484A1
(en)
|
2024-05-21 |
2025-12-11 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|
|
NL2037811B1
(en)
|
2024-05-29 |
2025-12-12 |
Univ Oslo |
Treatment for Cancer
|
|
WO2025250819A1
(en)
|
2024-05-31 |
2025-12-04 |
Kite Pharma, Inc. |
Tricistronic constructs for anti-gpc3 car
|
|
WO2025255030A1
(en)
|
2024-06-03 |
2025-12-11 |
Cornell University |
Interferon gamma responsive chimeric t cell costimulatory receptor
|
|
NL2037929B1
(en)
|
2024-06-11 |
2026-01-12 |
Prinses Maxima Centrum Voor Kinderoncologie B V |
Brain Organoid
|
|
WO2025259578A1
(en)
|
2024-06-11 |
2025-12-18 |
Kite Pharma, Inc. |
Methods for generating engineered lymphocytes
|
|
WO2026006682A1
(en)
|
2024-06-27 |
2026-01-02 |
Lentigen Technology, Inc. |
Chimeric antigen receptor therapies for treating cancer with il7fc armored car-t cells
|
|
WO2026006767A1
(en)
|
2024-06-28 |
2026-01-02 |
Dispatch Biotherapeutics, Inc. |
Tethered il-9/il-9r and related engineered cells and methods
|
|
WO2026015450A1
(en)
|
2024-07-06 |
2026-01-15 |
Tr1X, Inc. |
Cd4+ t cells expressing il-10 and chimeric antigen receptors and uses thereof
|
|
US20260009001A1
(en)
|
2024-07-08 |
2026-01-08 |
Kite Pharma, Inc. |
Systems and methods for applying mechanical force to living cells to generate a phenotypic response
|
|
WO2026020055A2
(en)
|
2024-07-18 |
2026-01-22 |
Juno Therapeutics, Inc. |
Methods for assessing exosomes in a cell composition and related uses
|
|
WO2026025092A1
(en)
|
2024-07-26 |
2026-01-29 |
Juno Therapeutics, Inc. |
Synthetic promoters for t cell expression
|
|
WO2026039365A1
(en)
|
2024-08-12 |
2026-02-19 |
Gilead Sciences, Inc. |
Kras modulating compounds
|
|
US20260108629A1
(en)
|
2024-08-14 |
2026-04-23 |
Kite Pharma, Inc. |
Vectors for production of therapeutic constructs
|
|
WO2026050426A2
(en)
|
2024-08-28 |
2026-03-05 |
Juno Therapeutics, Inc. |
Cd19-directed chimeric antigen receptor cell therapy for treating autoimmune and neurological diseases
|
|
WO2026047626A1
(en)
|
2024-08-30 |
2026-03-05 |
Inceptor Bio, Llc |
Compositions and methods involving immune cells engineered for binding bispecific antibodies for use in cell therapy
|
|
WO2026055342A1
(en)
|
2024-09-04 |
2026-03-12 |
Arsenal Biosciences, Inc. |
Synthetic pathway activators
|
|
WO2026062222A1
(en)
|
2024-09-20 |
2026-03-26 |
Institut Curie |
Novel protein isoforms and uses
|
|
WO2026069206A1
(en)
|
2024-09-25 |
2026-04-02 |
Takeda Pharmaceutical Company Limited |
Hypoimmunogenic modified gamma delta t cells
|
|
WO2026069200A1
(en)
|
2024-09-25 |
2026-04-02 |
Novartis Ag |
Treatment of neuroimmune diseases using a population of cd19 car-expressing cells
|