ES2162823T3 - Inmunoglobulinas desprovistas de cadenas ligeras. - Google Patents

Inmunoglobulinas desprovistas de cadenas ligeras.

Info

Publication number
ES2162823T3
ES2162823T3 ES93919098T ES93919098T ES2162823T3 ES 2162823 T3 ES2162823 T3 ES 2162823T3 ES 93919098 T ES93919098 T ES 93919098T ES 93919098 T ES93919098 T ES 93919098T ES 2162823 T3 ES2162823 T3 ES 2162823T3
Authority
ES
Spain
Prior art keywords
desprovistas
immunoglobulins
light chains
antigen binding
polypeptide chains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93919098T
Other languages
English (en)
Other versions
ES2162823T5 (es
Inventor
Cecile Casterman
Raymond Hamers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vrije Universiteit Brussel VUB
Universite Libre de Bruxelles ULB
Original Assignee
Vrije Universiteit Brussel VUB
Universite Libre de Bruxelles ULB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26132410&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2162823(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP92402326A external-priority patent/EP0584421A1/en
Application filed by Vrije Universiteit Brussel VUB, Universite Libre de Bruxelles ULB filed Critical Vrije Universiteit Brussel VUB
Application granted granted Critical
Publication of ES2162823T3 publication Critical patent/ES2162823T3/es
Publication of ES2162823T5 publication Critical patent/ES2162823T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/866—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody fragment, e.g. fab', fab, fv, fc, heavy chain or light chain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

EL INVENTO SE REFIERE A INMUNOGLOBULINA AISLADA CARACTERIZADA EN QUE COMPRENDEN DOS CADENAS DE POLIPEPTIDOS PESADOS SUFICIENTES PARA LA FORMACION DE UN LUGAR DE ENLACE ANTIGEN COMPLETO O LUGARES DE ENLACE DE ANTIGENO DIVERSO, ESTANDO ADEMAS ESTA INMUNOGLOBULINA DESPROVISTA DE CADENAS POLIPEPTIDAS LIGERAS.
ES93919098T 1992-08-21 1993-08-18 Inmunoglobulinas desprovistas de cadenas ligeras. Expired - Lifetime ES2162823T5 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP92402326A EP0584421A1 (en) 1992-08-21 1992-08-21 Immunoglobulins devoid of light chains
EP92402326 1992-08-21
EP93401310 1993-05-21
EP93401310 1993-05-21

Publications (2)

Publication Number Publication Date
ES2162823T3 true ES2162823T3 (es) 2002-01-16
ES2162823T5 ES2162823T5 (es) 2010-08-09

Family

ID=26132410

Family Applications (5)

Application Number Title Priority Date Filing Date
ES00127968T Expired - Lifetime ES2322324T3 (es) 1992-08-21 1993-08-18 Inmumoglobulinas desprovistas de cadenas ligeras.
ES05020889T Expired - Lifetime ES2325541T3 (es) 1992-08-21 1993-08-18 Inmunoglobulinas desprovistas de cadenas ligeras.
ES05008358T Expired - Lifetime ES2338791T3 (es) 1992-08-21 1993-08-18 Inmunoglobulinas desprovistas de cadenas ligeras.
ES04077639T Expired - Lifetime ES2338321T3 (es) 1992-08-21 1993-08-18 Inmunoglobulinas desprovistas de cadenas ligeras.
ES93919098T Expired - Lifetime ES2162823T5 (es) 1992-08-21 1993-08-18 Inmunoglobulinas desprovistas de cadenas ligeras.

Family Applications Before (4)

Application Number Title Priority Date Filing Date
ES00127968T Expired - Lifetime ES2322324T3 (es) 1992-08-21 1993-08-18 Inmumoglobulinas desprovistas de cadenas ligeras.
ES05020889T Expired - Lifetime ES2325541T3 (es) 1992-08-21 1993-08-18 Inmunoglobulinas desprovistas de cadenas ligeras.
ES05008358T Expired - Lifetime ES2338791T3 (es) 1992-08-21 1993-08-18 Inmunoglobulinas desprovistas de cadenas ligeras.
ES04077639T Expired - Lifetime ES2338321T3 (es) 1992-08-21 1993-08-18 Inmunoglobulinas desprovistas de cadenas ligeras.

Country Status (13)

Country Link
US (5) US5874541A (es)
EP (6) EP1087013B1 (es)
JP (4) JP3444885B2 (es)
AT (5) ATE452207T1 (es)
AU (1) AU701578B2 (es)
CA (1) CA2142331C (es)
DE (6) DE69330523D1 (es)
DK (5) DK1621554T4 (es)
ES (5) ES2322324T3 (es)
FI (3) FI115462B (es)
GR (1) GR3037024T3 (es)
PT (5) PT1621554E (es)
WO (1) WO1994004678A1 (es)

Families Citing this family (1178)

* Cited by examiner, † Cited by third party
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US6765087B1 (en) * 1992-08-21 2004-07-20 Vrije Universiteit Brussel Immunoglobulins devoid of light chains
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