MX2008013397A - Analisis de perfilamiento de expresion diferencial de fenotipos de cultivo celular y usos de los mismos. - Google Patents

Analisis de perfilamiento de expresion diferencial de fenotipos de cultivo celular y usos de los mismos.

Info

Publication number
MX2008013397A
MX2008013397A MX2008013397A MX2008013397A MX2008013397A MX 2008013397 A MX2008013397 A MX 2008013397A MX 2008013397 A MX2008013397 A MX 2008013397A MX 2008013397 A MX2008013397 A MX 2008013397A MX 2008013397 A MX2008013397 A MX 2008013397A
Authority
MX
Mexico
Prior art keywords
expression profiling
cell culture
profiling analysis
differential expression
culture phenotypes
Prior art date
Application number
MX2008013397A
Other languages
English (en)
Inventor
Martin S Sinacore
Timothy S Charlebois
Mark Melville
Karin Anderson
Niall Barron
Martin Clynes
Dana L Di Nino
Padraig Doolan
Patrick Gammel
Kathleen Kopycinski
Mark Leonard
Kevin M Mccarthy
Paula Meleadypaula Meleady
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MX2008013397A publication Critical patent/MX2008013397A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención proporciona los métodos para identificar sistemáticamente los genes y las proteínas y las vías relacionadas que elevan al máximo la expresión y secreción de proteínas por análisis de perfilamiento de expresión. La presente invención proporciona además los métodos para manipular los genes identificados y las proteínas para manipular por ingeniería las líneas celulares mejoradas.
MX2008013397A 2006-04-21 2007-04-21 Analisis de perfilamiento de expresion diferencial de fenotipos de cultivo celular y usos de los mismos. MX2008013397A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79429906P 2006-04-21 2006-04-21
US89741207P 2007-01-25 2007-01-25
PCT/US2007/010002 WO2008054514A2 (en) 2006-04-21 2007-04-21 Differential expression profiling analysis of cell culture phenotypes and the uses thereof

Publications (1)

Publication Number Publication Date
MX2008013397A true MX2008013397A (es) 2009-03-27

Family

ID=39092761

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008013397A MX2008013397A (es) 2006-04-21 2007-04-21 Analisis de perfilamiento de expresion diferencial de fenotipos de cultivo celular y usos de los mismos.

Country Status (8)

Country Link
US (1) US20080070268A1 (es)
EP (2) EP2010910A2 (es)
JP (1) JP2009534036A (es)
AU (1) AU2007314524A1 (es)
BR (1) BRPI0710637A2 (es)
CA (1) CA2649859A1 (es)
MX (1) MX2008013397A (es)
WO (1) WO2008054514A2 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008157299A2 (en) * 2007-06-15 2008-12-24 Wyeth Differential expression profiling analysis of cell culture phenotypes and uses thereof
US20090186358A1 (en) * 2007-12-21 2009-07-23 Wyeth Pathway Analysis of Cell Culture Phenotypes and Uses Thereof
ES2358829B1 (es) 2009-10-23 2012-06-25 Lipotec, S.A. Péptidos útiles en el tratamiento y/o cuidado de la piel, mucosas y/o cabello y su uso en composiciones cosméticas o farmacéuticas.
US8524458B2 (en) 2009-11-09 2013-09-03 Abbvie Inc. Secretory protein biomarkers for high efficiency protein expression
US9932591B2 (en) 2013-12-18 2018-04-03 University Of Delaware Reduction of lipase activity in product formulations
GB201322574D0 (en) * 2013-12-19 2014-02-05 Equigerminal Sa Retroviral peptides
JP6507542B2 (ja) * 2014-09-22 2019-05-08 東洋紡株式会社 バイオマーカーを用いた組換えタンパク質生産量の予測方法
US10913984B2 (en) 2014-11-12 2021-02-09 Lek Pharmaceuticals D.D. Predicting genetically stable recombinant protein production in early cell line development
EP4148139A4 (en) 2020-06-19 2023-11-08 FUJIFILM Corporation METHOD FOR IDENTIFYING BIOMARKERS AND METHOD FOR PRODUCING CELLS
KR102599650B1 (ko) * 2020-11-12 2023-11-08 서울대학교산학협력단 신규한 지질펩티드 화합물, 이의 생산 방법, 및 이의 용도

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US6765087B1 (en) * 1992-08-21 2004-07-20 Vrije Universiteit Brussel Immunoglobulins devoid of light chains
DK0656946T4 (da) * 1992-08-21 2010-07-26 Univ Bruxelles Immunoglobuliner uden lette kæder
US6005079A (en) * 1992-08-21 1999-12-21 Vrije Universiteit Brussels Immunoglobulins devoid of light chains
US5631734A (en) * 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
US6914137B2 (en) * 1997-12-06 2005-07-05 Dna Research Innovations Limited Isolation of nucleic acids
CN1230440C (zh) 1997-12-06 2005-12-07 Dna研究创新有限公司 核酸的分离
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
EP2295606A1 (en) * 2000-11-28 2011-03-16 Wyeth LLC Expression analysis of KIAA nucleic acids and polypeptides useful in the diagnosis and treatment of prostate cancer
WO2005111246A1 (en) 2004-05-11 2005-11-24 Wyeth Oligonucleotide arrays to monitor gene expression and methods for making and using same

Also Published As

Publication number Publication date
WO2008054514A8 (en) 2009-03-19
AU2007314524A1 (en) 2008-05-08
EP2423684A2 (en) 2012-02-29
BRPI0710637A2 (pt) 2012-03-13
JP2009534036A (ja) 2009-09-24
EP2423684A3 (en) 2012-06-27
US20080070268A1 (en) 2008-03-20
EP2010910A2 (en) 2009-01-07
WO2008054514A2 (en) 2008-05-08
CA2649859A1 (en) 2008-05-08
WO2008054514A3 (en) 2008-07-10

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Legal Events

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