US7060808B1
(en)
*
|
1995-06-07 |
2006-06-13 |
Imclone Systems Incorporated |
Humanized anti-EGF receptor monoclonal antibody
|
US20030224001A1
(en)
*
|
1998-03-19 |
2003-12-04 |
Goldstein Neil I. |
Antibody and antibody fragments for inhibiting the growth of tumors
|
ZA200007412B
(en)
*
|
1998-05-15 |
2002-03-12 |
Imclone Systems Inc |
Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases.
|
HUP0201480A3
(en)
*
|
1999-05-14 |
2009-03-30 |
Imclone Systems Inc |
Treatment of refractory human tumors with epidermal growth factor receptor antagonists
|
EP1311291A4
(de)
*
|
2000-08-09 |
2007-07-25 |
Imclone Systems Inc |
Behandlung von hyperproliferativen krankheiten mit antagonisten des epidermalen wachstumsfaktors
|
US20080008704A1
(en)
*
|
2001-03-16 |
2008-01-10 |
Mark Rubin |
Methods of treating colorectal cancer with anti-epidermal growth factor antibodies
|
JP2005289809A
(ja)
*
|
2001-10-24 |
2005-10-20 |
Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) |
突然変異重鎖抗体
|
US7696320B2
(en)
|
2004-08-24 |
2010-04-13 |
Domantis Limited |
Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
US9028822B2
(en)
|
2002-06-28 |
2015-05-12 |
Domantis Limited |
Antagonists against TNFR1 and methods of use therefor
|
EP1527346B1
(de)
|
2002-08-07 |
2011-06-08 |
Ablynx N.V. |
Modulation der blutplättchen-adhäsion basierend auf dem oberflächen-exponierten beta-switch loop des blutplättchen-glycoproteins ib-alpha
|
US20100003253A1
(en)
*
|
2002-11-08 |
2010-01-07 |
Ablynx N.V. |
Single domain antibodies directed against epidermal growth factor receptor and uses therefor
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
NZ540196A
(en)
*
|
2002-11-08 |
2008-09-26 |
Ablynx Nv |
Camelidae antibodies against imminoglobulin E and use thereof for the treatment of allergic disorders
|
ES2466716T3
(es)
*
|
2002-11-08 |
2014-06-11 |
Ablynx N.V. |
Anticuerpos de un solo dominio estabilizados
|
AU2003286002B2
(en)
*
|
2002-11-08 |
2011-06-16 |
Ablynx N.V. |
Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
|
US20060034845A1
(en)
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
EP1587838B1
(de)
|
2003-01-10 |
2015-04-15 |
Ablynx N.V. |
Therapeutische polypeptide, deren homologe, deren fragmente und deren verwendung bei der modulierung der thrombozytenvermittelten aggregation
|
WO2005077980A2
(en)
*
|
2004-02-13 |
2005-08-25 |
Bioceros Bv |
Soluble tcr-like molecules and their uses
|
DK1735348T3
(da)
*
|
2004-03-19 |
2012-07-16 |
Imclone Llc |
Humant anti-epidermalt vækstfaktorreceptorantistof
|
RU2401842C2
(ru)
|
2004-10-08 |
2010-10-20 |
Домантис Лимитед |
Антагонисты и способы их применения
|
CA2593328C
(en)
|
2005-01-14 |
2018-02-06 |
Ablynx N.V. |
Methods and assays for distinguishing between different forms of diseases and disorders characterized by thrombocytopenia and/or by spontaneous interaction between von willebrand factor (vwf) and platelets
|
PL1888640T3
(pl)
|
2005-05-18 |
2012-08-31 |
Ablynx Nv |
Ulepszone nanociała skierowane przeciwko czynnikowi martwicy nowotworów typu alfa
|
NZ563392A
(en)
|
2005-05-20 |
2009-12-24 |
Ablynx Nv |
Improved Nanobodies(TM) for the treatment of aggregation-mediated disorders
|
DE102005023617A1
(de)
*
|
2005-05-21 |
2006-11-23 |
Aspre Ag |
Verfahren zum Mischen von Farben in einem Display
|
CA2625951A1
(en)
*
|
2005-09-01 |
2007-03-08 |
National Research Council Of Canada |
Anti-apoptotic protein antibodies
|
WO2007042289A2
(en)
*
|
2005-10-11 |
2007-04-19 |
Ablynx N.V. |
Nanobodies™ and polypeptides against egfr and igf-ir
|
CA2632417A1
(en)
*
|
2005-12-06 |
2007-06-14 |
Domantis Limited |
Ligands that have binding specificity for egfr and/or vegf and methods of use therefor
|
TW200738750A
(en)
*
|
2005-12-06 |
2007-10-16 |
Domantis Ltd |
Ligands and methods of use therefor
|
WO2007104529A2
(en)
*
|
2006-03-13 |
2007-09-20 |
Ablynx N.V. |
Amino acid sequences directed against il-6 and polypeptides comprising the same for the treatment of diseases and disorders associated with il-6-mediated signalling
|
WO2007110219A1
(en)
*
|
2006-03-27 |
2007-10-04 |
Ablynx N.V. |
Medical delivery device for therapeutic proteins based on single domain antibodies
|
US20070269422A1
(en)
*
|
2006-05-17 |
2007-11-22 |
Ablynx N.V. |
Serum albumin binding proteins with long half-lives
|
JP2010505435A
(ja)
*
|
2006-10-11 |
2010-02-25 |
アブリンクス エン.ヴェー. |
本質的にpHに非依存的に血清タンパク質に結合するアミノ酸配列、それを含む化合物、およびその使用
|
GB0621513D0
(en)
|
2006-10-30 |
2006-12-06 |
Domantis Ltd |
Novel polypeptides and uses thereof
|
KR20090110295A
(ko)
|
2006-11-22 |
2009-10-21 |
에드넥서스, 어 브리스톨-마이어스 스퀴브 알&디 컴파니 |
Igf-ir을 포함하는 티로신 키나제 수용체에 대한 공학처리된 단백질에 기반한 표적화 치료제
|
JP2010511397A
(ja)
*
|
2006-12-05 |
2010-04-15 |
アブリンクス エン.ヴェー. |
血清タンパク質と結合可能なペプチド
|
CA2673331A1
(en)
|
2006-12-19 |
2008-06-26 |
Ablynx N.V. |
Amino acid sequences directed against gpcrs and polypeptides comprising the same for the treatment of gpcr-related diseases and disorders
|
AU2007336243B2
(en)
|
2006-12-19 |
2012-07-26 |
Ablynx N.V. |
Amino acid sequences directed against a metalloproteinase from the ADAM family and polypeptides comprising the same for the treatment of ADAM-related diseases and disorders
|
CA2588106A1
(en)
*
|
2007-05-18 |
2008-11-18 |
Nrc - Institute For Biological Sciences |
Single-domain antibodies and heavy chain antibody against egfr and uses thereof
|
CA2691940C
(en)
|
2007-07-03 |
2018-03-06 |
Joost Alexander Kolkman |
Methods for providing improved immunoglobulin sequences
|
CA2697719A1
(en)
*
|
2007-08-27 |
2009-03-05 |
Ablynx Nv |
Needle-free delivery device for therapeutic proteins based on single antigen-binding domains such as nanobodies
|
WO2009068628A1
(en)
|
2007-11-27 |
2009-06-04 |
Ablynx N.V. |
Constructs comprising single variable domains and an fc portion derived from lge.
|
WO2009102421A2
(en)
|
2008-02-14 |
2009-08-20 |
Bristol-Myers Squibb Company |
Targeted therapeutics based on engineered proteins that bind egfr
|
US20110091462A1
(en)
|
2008-03-05 |
2011-04-21 |
Ablynx N.V. |
Novel antigen binding dimer-complexes, methods of making and uses thereof
|
EP2260058A2
(de)
|
2008-04-07 |
2010-12-15 |
Ablynx N.V. |
Variable einzeldomänen gegen notch-signalwege
|
CA2721202A1
(en)
|
2008-04-17 |
2009-10-22 |
Hilde Adi Pierrette Revets |
Peptides capable of binding to serum proteins and compounds, constructs and polypeptides comprising the same
|
CN102099373A
(zh)
|
2008-05-22 |
2011-06-15 |
百时美施贵宝公司 |
基于纤连蛋白的多价支架结构域蛋白
|
US8444976B2
(en)
|
2008-07-02 |
2013-05-21 |
Argen-X B.V. |
Antigen binding polypeptides
|
WO2010042815A2
(en)
*
|
2008-10-09 |
2010-04-15 |
Duke University |
Vhh antibody fragments for use in the detection and treatment of cancer
|
CA2740561C
(en)
*
|
2008-10-14 |
2021-01-19 |
National Research Council Of Canada |
Bsa-specific antibodies
|
US10118962B2
(en)
|
2008-10-29 |
2018-11-06 |
Ablynx N.V. |
Methods for purification of single domain antigen binding molecules
|
RU2481824C2
(ru)
|
2008-10-29 |
2013-05-20 |
Аблинкс Н.В |
Препараты однодоменных антигенсвязывающих молекул
|
US9260508B2
(en)
|
2008-12-19 |
2016-02-16 |
Ablynx N.V. |
Method for generation of immunoglobulin sequences
|
WO2010100135A1
(en)
|
2009-03-05 |
2010-09-10 |
Ablynx N.V. |
Novel antigen binding dimer-complexes, methods of making/avoiding and uses thereof
|
US9265834B2
(en)
|
2009-03-05 |
2016-02-23 |
Ablynx N.V. |
Stable formulations of polypeptides and uses thereof
|
AU2010243551B2
(en)
|
2009-04-30 |
2015-03-26 |
Ablynx Nv |
Method for the production of domain antibodies
|
WO2011003622A1
(en)
|
2009-07-10 |
2011-01-13 |
Ablynx N.V. |
Method for the production of variable domains
|
EP2473528B1
(de)
|
2009-09-03 |
2014-12-03 |
Ablynx N.V. |
Stabile formulierungen aus polypeptiden und verwendungen davon
|
US20110195494A1
(en)
|
2009-10-02 |
2011-08-11 |
Boehringer Ingelheim International Gmbh |
Dll4-binging molecules
|
US20110172398A1
(en)
|
2009-10-02 |
2011-07-14 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules for anti-angiogenesis therapy
|
WO2011083140A1
(en)
|
2010-01-08 |
2011-07-14 |
Ablynx Nv |
Immunoglobulin single variable domain directed against human cxcr4
|
AU2011212442A1
(en)
|
2010-02-05 |
2012-08-09 |
Ablynx Nv |
Peptides capable of binding to serum albumin and compounds, constructs and polypeptides comprising the same
|
EP2533761B1
(de)
|
2010-02-11 |
2019-03-27 |
Ablynx N.V. |
Verfahren und zusammensetzungen zur herstellung von aerosolen
|
SG183369A1
(en)
|
2010-03-03 |
2012-09-27 |
Boehringer Ingelheim Int |
Biparatopic abeta binding polypeptides
|
US9101674B2
(en)
|
2010-03-29 |
2015-08-11 |
Vib Vzw |
Targeting and in vivo imaging of tumor-associated macrophages
|
US9556273B2
(en)
|
2010-03-29 |
2017-01-31 |
Vib Vzw |
Anti-macrophage mannose receptor single variable domains for targeting and in vivo imaging of tumor-associated macrophages
|
SG185366A1
(en)
|
2010-05-04 |
2012-12-28 |
Merrimack Pharmaceuticals Inc |
Antibodies against epidermal growth factor receptor (egfr) and uses thereof
|
WO2011161263A1
(en)
|
2010-06-25 |
2011-12-29 |
Ablynx Nv |
Pharmaceutical compositions for cutaneous administration
|
US20120225081A1
(en)
|
2010-09-03 |
2012-09-06 |
Boehringer Ingelheim International Gmbh |
Vegf-binding molecules
|
WO2012042026A1
(en)
|
2010-09-30 |
2012-04-05 |
Ablynx Nv |
Biological materials related to c-met
|
US20130261288A1
(en)
|
2010-10-29 |
2013-10-03 |
Ablynx N.V. |
Method for the production of immunoglobulin single variable domains
|
AU2012234282B2
(en)
|
2011-03-28 |
2015-07-16 |
Ablynx Nv |
Method for producing solid formulations comprising immunoglobulin single variable domains
|
US9527925B2
(en)
|
2011-04-01 |
2016-12-27 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules binding to VEGF and ANG2
|
US20130078247A1
(en)
|
2011-04-01 |
2013-03-28 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules binding to dii4 and ang2
|
EP2707382B1
(de)
|
2011-05-09 |
2019-07-17 |
Ablynx NV |
Verfahren zur herstellung von variablen immunglobulin-einzeldomänen
|
KR102072250B1
(ko)
|
2011-05-27 |
2020-03-02 |
아블린쓰 엔.브이. |
Rankl 결합 펩티드를 이용한 골 재흡수 억제
|
WO2012166906A1
(en)
|
2011-05-31 |
2012-12-06 |
Massachusetts Institute Of Technology |
Cell-directed synthesis of multifunctional nanopatterns and nanomaterials
|
US8691231B2
(en)
|
2011-06-03 |
2014-04-08 |
Merrimack Pharmaceuticals, Inc. |
Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibodies
|
EP2723772A1
(de)
|
2011-06-23 |
2014-04-30 |
Ablynx N.V. |
Gegen ige gerichtete variable immunglobulin-einzeldomänen
|
US10138302B2
(en)
|
2011-09-23 |
2018-11-27 |
Ablynx N.V. |
Methods for treating rheumatoid arthritis by administering interleukin-6 receptor antibodies
|
JP6219287B2
(ja)
|
2011-09-30 |
2017-10-25 |
アブリンクス エン.ヴェー. |
c−Metに関連する生物学的物質
|
DE102011121237A1
(de)
*
|
2011-12-14 |
2013-06-20 |
Universitätsklinikum Hamburg-Eppendorf |
Einzeldomänen-Antikörper gegen Clostridium difficile Toxin CDTa
|
NZ628584A
(en)
|
2012-03-30 |
2016-04-29 |
Boehringer Ingelheim Int |
Ang2-binding molecules
|
JP6411333B2
(ja)
|
2012-05-24 |
2018-10-24 |
ブイアイビー ブイゼットダブリュVib Vzw |
腫瘍関連マクロファージのターゲティングおよびinvivoイメージング用抗マクロファージマンノース受容体単一可変ドメイン
|
US11339208B1
(en)
|
2012-05-31 |
2022-05-24 |
United States Of America As Represented By The Secretary Of The Air Force |
Camelidae single-domain antibodies against Yersinia pestis and methods of use
|
WO2014087010A1
(en)
|
2012-12-07 |
2014-06-12 |
Ablynx N.V. |
IMPROVED POLYPEPTIDES DIRECTED AGAINST IgE
|
WO2014122183A1
(en)
|
2013-02-05 |
2014-08-14 |
Vib Vzw |
Muscarinic acetylcholine receptor binding agents and uses thereof
|
NO2951201T3
(de)
|
2013-02-08 |
2018-03-17 |
|
|
JP6499090B2
(ja)
|
2013-03-15 |
2019-04-10 |
ブイアイビー ブイゼットダブリュVib Vzw |
心血管疾患において使用するための抗マクロファージマンノース受容体単一可変ドメイン
|
NL1040254C2
(en)
|
2013-05-17 |
2014-11-24 |
Ablynx Nv |
Stable formulations of immunoglobulin single variable domains and uses thereof.
|
MA39599A
(fr)
|
2014-05-14 |
2016-10-05 |
Merrimack Pharmaceuticals Inc |
Dosage et administration d'agents thérapeutiques anti-egfr
|
NL2013661B1
(en)
|
2014-10-21 |
2016-10-05 |
Ablynx Nv |
KV1.3 Binding immunoglobulins.
|
WO2016012363A1
(en)
|
2014-07-22 |
2016-01-28 |
Vib Vzw |
Methods to select for agents that stabilize protein complexes
|
ES2772348T3
(es)
|
2014-12-19 |
2020-07-07 |
Ablynx Nv |
Dímeros de Nanobody con uniones cisteína
|
EP3294768B1
(de)
|
2015-05-13 |
2019-08-21 |
Ablynx N.V. |
T-zell-rekrutierende polypeptide auf basis von tcr-alpa/beta-reaktivität
|
AU2016260909B2
(en)
|
2015-05-13 |
2019-08-22 |
Ablynx N.V. |
T cell recruiting polypeptides based on CD3 reactivity
|
NO2768984T3
(de)
|
2015-11-12 |
2018-06-09 |
|
|
JO3744B1
(ar)
|
2015-11-18 |
2021-01-31 |
Merck Sharp & Dohme |
مواد ربط لـpd1 و/ أو lag3
|
JO3739B1
(ar)
|
2015-11-18 |
2021-01-31 |
Merck Sharp & Dohme |
روابط ctla4
|
MX2018006243A
(es)
|
2015-11-18 |
2018-11-09 |
Merck Sharp & Dohme |
Proteinas de union a pd1/ctla4.
|
KR20180080337A
(ko)
|
2015-11-27 |
2018-07-11 |
아블린쓰 엔.브이. |
Cd40l을 억제하는 폴리펩티드
|
WO2017191108A1
(en)
|
2016-05-02 |
2017-11-09 |
Ablynx Nv |
Treatment of rsv infection
|
WO2018007442A1
(en)
|
2016-07-06 |
2018-01-11 |
Ablynx N.V. |
Treatment of il-6r related diseases
|
WO2018029182A1
(en)
|
2016-08-08 |
2018-02-15 |
Ablynx N.V. |
Il-6r single variable domain antibodies for treatment of il-6r related diseases
|
WO2018050833A1
(en)
|
2016-09-15 |
2018-03-22 |
Ablynx Nv |
Immunoglobulin single variable domains directed against macrophage migration inhibitory factor
|
WO2018091606A1
(en)
|
2016-11-16 |
2018-05-24 |
Ablynx Nv |
T cell recruiting polypeptides capable of binding cd123 and tcr alpha/beta
|
WO2018099968A1
(en)
|
2016-11-29 |
2018-06-07 |
Ablynx N.V. |
Treatment of infection by respiratory syncytial virus (rsv)
|
CA3054623A1
(en)
|
2017-02-28 |
2018-09-07 |
Vib Vzw |
Means and methods for oral protein delivery
|
JP2020519261A
(ja)
|
2017-05-11 |
2020-07-02 |
ブイアイビー ブイゼットダブリュVib Vzw |
可変免疫グロブリンドメインのグリコシル化
|
MX2019014400A
(es)
|
2017-06-02 |
2020-02-10 |
Merck Patent Gmbh |
Inmunoglobulinas que se unen a adamts.
|
US11603401B2
(en)
|
2017-06-02 |
2023-03-14 |
Ablynx N.V. |
Aggrecan binding immunoglobulins
|
BR112019025097A2
(pt)
|
2017-06-02 |
2020-07-28 |
Merck Patent Gmbh |
imunoglobulinas de ligação a mmp13
|
BR112019025147A2
(pt)
|
2017-06-02 |
2020-06-23 |
Merck Patent Gmbh |
Polipeptídeos que ligam adamts5, mmp13 e aggrecan
|
US11155607B2
(en)
|
2017-07-19 |
2021-10-26 |
Vib Vzw |
Serum albumin binding agents
|
WO2019055955A1
(en)
|
2017-09-18 |
2019-03-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
IMMUNOTOXINS WITH ALBUMIN BINDING DOMAIN
|
WO2019086548A1
(en)
|
2017-10-31 |
2019-05-09 |
Vib Vzw |
Novel antigen-binding chimeric proteins and methods and uses thereof
|
WO2019096874A1
(en)
|
2017-11-15 |
2019-05-23 |
Novo Nordisk A/S |
Factor x binders enhancing fx activation
|
WO2019155041A1
(en)
|
2018-02-12 |
2019-08-15 |
Vib Vzw |
Gβγ COMPLEX ANTIBODIES AND USES THEREOF
|
US11858960B2
(en)
|
2018-03-01 |
2024-01-02 |
Vrije Universiteit Brussel |
Human PD-L1-binding immunoglobulins
|
CN111936516B
(zh)
*
|
2018-03-19 |
2023-03-03 |
上海药明生物技术有限公司 |
新型抗egfr抗体多肽
|
EP3636657A1
(de)
|
2018-10-08 |
2020-04-15 |
Ablynx N.V. |
Chromatographiefreies antikörperreinigungsverfahren
|
EP3963329A1
(de)
|
2019-04-29 |
2022-03-09 |
Confo Therapeutics N.V. |
Screening-verfahren und assays zur verwendung mit transmembranproteinen, insbesondere mit gpcrs
|
WO2020221888A1
(en)
|
2019-04-30 |
2020-11-05 |
Vib Vzw |
Cystic fibrosis transmembrane conductance regulator stabilizing agents
|
EP3976650A1
(de)
|
2019-05-28 |
2022-04-06 |
Vib Vzw |
Krebsbehandlung durch abzielen auf plexine im immunbereich
|
EP3976067A1
(de)
|
2019-05-28 |
2022-04-06 |
Vib Vzw |
Cd8+-t-zellen ohne plexine und ihre anwendung zur krebsbehandlung
|
EP3799881A1
(de)
|
2019-10-04 |
2021-04-07 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Einzeldomänenantikörper, die spezifisch globo binden serie glycane
|
US20220380456A1
(en)
|
2019-10-21 |
2022-12-01 |
Vib Vzw |
Nanodisc-specific antigen-binding chimeric proteins
|
JP2023501004A
(ja)
|
2019-11-11 |
2023-01-17 |
アイビーアイ-エージー イノベイティブ バイオ インセクティサイズ リミテッド |
昆虫防除ナノボディおよびその使用
|
WO2021097289A1
(en)
|
2019-11-15 |
2021-05-20 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Pegylated recombinant immunotoxins
|
EP4065603A1
(de)
|
2019-11-27 |
2022-10-05 |
Vib Vzw |
Positive allosterische modulatoren des calciumempfindlichen rezeptors
|
GB201918279D0
(en)
|
2019-12-12 |
2020-01-29 |
Vib Vzw |
Glycosylated single chain immunoglobulin domains
|
WO2021123360A1
(en)
|
2019-12-20 |
2021-06-24 |
Vib Vzw |
Nanobody exchange chromatography
|
WO2021140205A1
(en)
|
2020-01-10 |
2021-07-15 |
Confo Therapeutics N.V. |
Methods for generating antibodies and antibody fragments and libraries comprising same
|
WO2021156490A2
(en)
|
2020-02-06 |
2021-08-12 |
Vib Vzw |
Corona virus binders
|
CA3173090A1
(en)
|
2020-02-25 |
2021-09-02 |
Vib Vzw |
Leucine-rich repeat kinase 2 allosteric modulators
|
US20230279115A1
(en)
|
2020-04-22 |
2023-09-07 |
Mabwell (shanghai) Bioscience Co., Ltd. |
Single variable domain antibody targeting human programmed death ligand 1 (pd-l1) and derivative thereof
|
WO2021229104A1
(en)
|
2020-05-15 |
2021-11-18 |
Université de Liège |
Anti-cd38 single-domain antibodies in disease monitoring and treatment
|
WO2022003156A1
(en)
|
2020-07-02 |
2022-01-06 |
Oncurious Nv |
Ccr8 non-blocking binders
|
US20230357424A1
(en)
*
|
2020-08-21 |
2023-11-09 |
Synthekine, Inc. |
Cd45 binding molecules and methods of use
|
WO2022063957A1
(en)
|
2020-09-24 |
2022-03-31 |
Vib Vzw |
Biomarker for anti-tumor therapy
|
CA3196737A1
(en)
|
2020-09-24 |
2022-03-31 |
Massimiliano Mazzone |
Combination of p2y6 inhibitors and immune checkpoint inhibitors
|
KR20230074527A
(ko)
|
2020-09-25 |
2023-05-30 |
아블린쓰 엔.브이. |
Il-13 및 ox40l을 표적으로 하는 면역글로불린 단일 가변 도메인을 포함하는 폴리펩티드
|
WO2022117572A2
(en)
|
2020-12-02 |
2022-06-09 |
Oncurious Nv |
An ltbr agonist in combination therapy against cancer
|
WO2022117569A1
(en)
|
2020-12-02 |
2022-06-09 |
Oncurious Nv |
A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer
|
TW202239763A
(zh)
|
2020-12-18 |
2022-10-16 |
比利時商艾伯霖克斯公司 |
包含靶向IL-6和TNF-α的免疫球蛋白單可變結構域的多肽
|
GB202020502D0
(en)
|
2020-12-23 |
2021-02-03 |
Vib Vzw |
Antibody composistion for treatment of corona virus infection
|
CA3206304A1
(en)
|
2020-12-24 |
2022-06-30 |
Vib Vzw |
Human ccr8 binders
|
US20240052044A1
(en)
|
2020-12-24 |
2024-02-15 |
Vib Vzw |
Non-blocking human ccr8 binders
|
US20240052045A1
(en)
|
2020-12-24 |
2024-02-15 |
Vib Vzw |
Murine cross-reactive human ccr8 binders
|
CN117794566A
(zh)
|
2021-02-05 |
2024-03-29 |
Vib研究所 |
沙贝病毒结合剂
|
JP2024506020A
(ja)
|
2021-02-05 |
2024-02-08 |
ブイアイビー ブイゼットダブリュ |
サルベコウイルス結合剤
|
WO2022175392A1
(en)
|
2021-02-17 |
2022-08-25 |
Vib Vzw |
Inhibition of slc4a4 in the treatment of cancer
|
IL305318A
(en)
|
2021-02-19 |
2023-10-01 |
Vib Vzw |
Cation-independent mannose-6-phosphate receptor binders
|
WO2022199804A1
(en)
|
2021-03-24 |
2022-09-29 |
Vib Vzw |
Nek6 inhibition to treat als and ftd
|
US20240261446A1
(en)
|
2021-05-17 |
2024-08-08 |
Université de Liège |
Anti-cd38 single domain antibodies in disease monitoring and treatment
|
EP4359421A1
(de)
|
2021-06-23 |
2024-05-01 |
Vib Vzw |
Mittel und verfahren zur auswahl spezifischer bindemittel
|
CN118562006A
(zh)
*
|
2021-06-24 |
2024-08-30 |
浙江纳米抗体技术中心有限公司 |
人表皮生长因子受体结合分子及其应用
|
CN117580865A
(zh)
|
2021-06-29 |
2024-02-20 |
山东先声生物制药有限公司 |
Cd16抗体及其应用
|
WO2023006040A1
(zh)
|
2021-07-30 |
2023-02-02 |
江苏先声药业有限公司 |
抗pvrig/抗tigit双特异性抗体和应用
|
CA3228014A1
(en)
|
2021-07-30 |
2023-02-16 |
Vib Vzm |
Cation-independent mannose-6-phosphate receptor binders for targeted protein degradation
|
EP4428156A1
(de)
|
2021-12-03 |
2024-09-11 |
Shandong Simcere Biopharmaceutical Co., Ltd. |
Anti-bcma-nanokörper und verwendung davon
|
WO2023111266A1
(en)
|
2021-12-17 |
2023-06-22 |
Ablynx Nv |
POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING TCRαβ, CD33 AND CD123
|
WO2023125888A1
(zh)
|
2021-12-31 |
2023-07-06 |
山东先声生物制药有限公司 |
一种gprc5d抗体及其应用
|
WO2023135198A1
(en)
|
2022-01-12 |
2023-07-20 |
Vib Vzw |
Human ntcp binders for therapeutic use and liver-specific targeted delivery
|
WO2023148397A1
(en)
|
2022-02-07 |
2023-08-10 |
Vib Vzw |
Engineered stabilizing aglycosylated fc-regions
|
WO2023198848A1
(en)
|
2022-04-13 |
2023-10-19 |
Vib Vzw |
An ltbr agonist in combination therapy against cancer
|
WO2023222825A1
(en)
|
2022-05-18 |
2023-11-23 |
Vib Vzw |
Sarbecovirus spike s2 subunit binders
|
WO2024008755A1
(en)
|
2022-07-04 |
2024-01-11 |
Vib Vzw |
Blood-cerebrospinal fluid barrier crossing antibodies
|
WO2024008904A2
(en)
|
2022-07-08 |
2024-01-11 |
Novo Nordisk A/S |
Highly potent isvd compounds capable of substituting for fviii(a)
|
WO2024068744A1
(en)
|
2022-09-27 |
2024-04-04 |
Vib Vzw |
Antivirals against human parainfluenza virus
|
WO2024105091A1
(en)
|
2022-11-15 |
2024-05-23 |
Imec Vzw |
Method and system for droplet manipulation
|
WO2024126805A1
(en)
|
2022-12-15 |
2024-06-20 |
Aarhus Universitet |
Synthetic activation of multimeric transmembrane receptors
|
WO2024133935A1
(en)
|
2022-12-23 |
2024-06-27 |
Ablynx Nv |
Protein-based conjugation carriers
|
WO2024156888A1
(en)
|
2023-01-27 |
2024-08-02 |
Vib Vzw |
Cd163-binding conjugates
|
WO2024156881A1
(en)
|
2023-01-27 |
2024-08-02 |
Vib Vzw |
CD8b-BINDING POLYPEPTIDES
|
WO2024170756A1
(en)
|
2023-02-17 |
2024-08-22 |
Ablynx N.V. |
Polypeptides binding to the neonatal fc receptor
|
WO2024175787A1
(en)
|
2023-02-24 |
2024-08-29 |
Vrije Universiteit Brussel |
Anti-inflammatory pannexin 1 channel inhibitors
|