LT2805731T - Stabilios polipeptidų kompozicijos ir jų panaudojimas - Google Patents
Stabilios polipeptidų kompozicijos ir jų panaudojimasInfo
- Publication number
- LT2805731T LT2805731T LTEP14171120.0T LT14171120T LT2805731T LT 2805731 T LT2805731 T LT 2805731T LT 14171120 T LT14171120 T LT 14171120T LT 2805731 T LT2805731 T LT 2805731T
- Authority
- LT
- Lithuania
- Prior art keywords
- polypeptides
- stable formulations
- formulations
- stable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27581609P | 2009-09-03 | 2009-09-03 | |
US28450209P | 2009-12-18 | 2009-12-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
LT2805731T true LT2805731T (lt) | 2019-02-11 |
Family
ID=42797362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP14171120.0T LT2805731T (lt) | 2009-09-03 | 2010-09-03 | Stabilios polipeptidų kompozicijos ir jų panaudojimas |
Country Status (12)
Country | Link |
---|---|
US (2) | US20120244158A1 (lt) |
EP (5) | EP3725330A1 (lt) |
CY (1) | CY1121411T1 (lt) |
DK (2) | DK2473528T3 (lt) |
ES (3) | ES2531083T3 (lt) |
HK (1) | HK1204284A1 (lt) |
HR (1) | HRP20190137T1 (lt) |
LT (1) | LT2805731T (lt) |
PL (2) | PL3438126T3 (lt) |
PT (3) | PT3438126T (lt) |
SI (1) | SI2805731T1 (lt) |
WO (2) | WO2011026948A1 (lt) |
Families Citing this family (27)
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KR20120125601A (ko) | 2007-05-24 | 2012-11-16 | 아블린쓰 엔.브이. | Rank-l에 대한 아미노산 서열, 및 이를 포함하는 골 질환 및 장애 치료용 폴리펩티드 |
EP2346900A1 (en) | 2008-10-29 | 2011-07-27 | Wyeth LLC | Methods for purification of single domain antigen binding molecules |
CN104740631B (zh) | 2008-10-29 | 2019-04-16 | 阿布林克斯公司 | 单域抗原结合性分子的制剂 |
US9265834B2 (en) | 2009-03-05 | 2016-02-23 | Ablynx N.V. | Stable formulations of polypeptides and uses thereof |
EP2403873A1 (en) | 2009-03-05 | 2012-01-11 | Ablynx N.V. | Novel antigen binding dimer-complexes, methods of making/avoiding and uses thereof |
EP2417163B1 (en) | 2009-04-10 | 2019-02-27 | Ablynx N.V. | Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders |
WO2010115995A2 (en) | 2009-04-10 | 2010-10-14 | Ablynx Nv | Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders |
PL3438126T3 (pl) * | 2009-09-03 | 2021-03-08 | Ablynx N.V. | Stabilne formulacje polipeptydów i ich zastosowanie |
US20110059079A1 (en) * | 2009-09-04 | 2011-03-10 | Xoma Technology Ltd. | Antibody Coformulations |
JP5951508B2 (ja) | 2010-02-11 | 2016-07-13 | アブリンクス エン.ヴェー. | エアロゾルの調製のための方法及び組成物 |
BR112012022258A2 (pt) | 2010-03-01 | 2016-10-25 | Bayer Healthcare Llc | anticorpos monoclonais otimizados contra inibidor de trajetória de fator de tecido ( tfpi) |
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EA201390812A1 (ru) * | 2010-12-02 | 2013-11-29 | Онколитикс Байотек Инк. | Лиофилизированные вирусные составы |
CN103347535B (zh) * | 2010-12-02 | 2015-11-25 | 昂科利蒂克斯生物科技公司 | 液体病毒制剂 |
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AU2012278836B2 (en) * | 2011-07-07 | 2016-03-10 | Lfb Usa, Inc. | Formulations that stabilize proteins |
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US9592297B2 (en) | 2012-08-31 | 2017-03-14 | Bayer Healthcare Llc | Antibody and protein formulations |
EP3003369A4 (en) * | 2013-05-28 | 2017-04-26 | Momenta Pharmaceuticals, Inc. | Pharmaceutical compositions comprising pyrophosphate |
EP3209327A1 (en) | 2014-10-21 | 2017-08-30 | Ablynx N.V. | Treatment of il-6r related diseases |
WO2018007442A1 (en) | 2016-07-06 | 2018-01-11 | Ablynx N.V. | Treatment of il-6r related diseases |
WO2018029182A1 (en) | 2016-08-08 | 2018-02-15 | Ablynx N.V. | Il-6r single variable domain antibodies for treatment of il-6r related diseases |
BR112019017853A2 (pt) * | 2017-02-28 | 2021-04-27 | Vib Vzw | Meios e métodos para liberação oral de proteína |
KR20200012935A (ko) | 2017-06-02 | 2020-02-05 | 메르크 파텐트 게엠베하 | Adamts 결합성 면역글로불린 |
CN113543772A (zh) * | 2019-03-08 | 2021-10-22 | 勃林格殷格翰国际有限公司 | 抗il-36r抗体制剂 |
CN114681592A (zh) * | 2020-12-31 | 2022-07-01 | 天境生物科技(杭州)有限公司 | 包含可溶性gp130二聚体的制剂和使用方法 |
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EP2356147A1 (en) * | 2008-11-26 | 2011-08-17 | Glaxo Group Limited | Polypeptides, antibody variable domains&antagonists |
DK2387583T3 (en) * | 2009-01-14 | 2019-01-14 | Ablynx Nv | PULMONAL ADMINISTRATION OF VARIABLE IMMUNGLOBULIN SINGLE DOMAINS AND CONSTRUCTIONS THEREOF. |
SG2014007637A (en) * | 2009-01-29 | 2014-03-28 | Medimmune Llc | Human anti-il-6 antibodies with extended in vivo half-life and their use in treatment of oncology, autoimmune diseases and inflammatory diseases |
US9265834B2 (en) | 2009-03-05 | 2016-02-23 | Ablynx N.V. | Stable formulations of polypeptides and uses thereof |
EP2403873A1 (en) | 2009-03-05 | 2012-01-11 | Ablynx N.V. | Novel antigen binding dimer-complexes, methods of making/avoiding and uses thereof |
PL3438126T3 (pl) * | 2009-09-03 | 2021-03-08 | Ablynx N.V. | Stabilne formulacje polipeptydów i ich zastosowanie |
-
2010
- 2010-09-03 PL PL18185772T patent/PL3438126T3/pl unknown
- 2010-09-03 EP EP20176028.7A patent/EP3725330A1/en active Pending
- 2010-09-03 WO PCT/EP2010/062975 patent/WO2011026948A1/en active Application Filing
- 2010-09-03 SI SI201031846T patent/SI2805731T1/sl unknown
- 2010-09-03 EP EP14171120.0A patent/EP2805731B1/en active Active
- 2010-09-03 LT LTEP14171120.0T patent/LT2805731T/lt unknown
- 2010-09-03 US US13/393,636 patent/US20120244158A1/en not_active Abandoned
- 2010-09-03 EP EP10747896.8A patent/EP2473528B1/en active Active
- 2010-09-03 DK DK10747896T patent/DK2473528T3/en active
- 2010-09-03 PT PT181857723T patent/PT3438126T/pt unknown
- 2010-09-03 ES ES10747896T patent/ES2531083T3/es active Active
- 2010-09-03 PT PT107478950T patent/PT2473527T/pt unknown
- 2010-09-03 ES ES10747895.0T patent/ES2617180T3/es active Active
- 2010-09-03 DK DK10747895.0T patent/DK2473527T3/en active
- 2010-09-03 WO PCT/EP2010/062972 patent/WO2011026945A1/en active Application Filing
- 2010-09-03 EP EP10747895.0A patent/EP2473527B1/en active Active
- 2010-09-03 ES ES18185772T patent/ES2831323T3/es active Active
- 2010-09-03 US US13/393,679 patent/US9884117B2/en active Active
- 2010-09-03 PT PT10747896T patent/PT2473528E/pt unknown
- 2010-09-03 EP EP18185772.3A patent/EP3438126B1/en active Active
- 2010-09-03 PL PL10747896T patent/PL2473528T3/pl unknown
-
2015
- 2015-05-22 HK HK15104885.3A patent/HK1204284A1/xx not_active IP Right Cessation
-
2019
- 2019-01-21 HR HRP20190137TT patent/HRP20190137T1/hr unknown
- 2019-01-31 CY CY20191100137T patent/CY1121411T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
SI2805731T1 (sl) | 2019-02-28 |
DK2473527T3 (en) | 2017-03-06 |
PT2473527T (pt) | 2017-02-27 |
PL2473528T3 (pl) | 2015-05-29 |
US9884117B2 (en) | 2018-02-06 |
EP2473528B1 (en) | 2014-12-03 |
DK2473528T3 (en) | 2015-03-02 |
EP2805731A3 (en) | 2015-04-01 |
CY1121411T1 (el) | 2020-05-29 |
WO2011026945A1 (en) | 2011-03-10 |
PT3438126T (pt) | 2020-11-09 |
PL3438126T3 (pl) | 2021-03-08 |
EP2473527A1 (en) | 2012-07-11 |
EP2473528A1 (en) | 2012-07-11 |
EP2805731A2 (en) | 2014-11-26 |
ES2831323T3 (es) | 2021-06-08 |
WO2011026948A1 (en) | 2011-03-10 |
HK1204284A1 (en) | 2015-11-13 |
ES2617180T3 (es) | 2017-06-15 |
EP2805731B1 (en) | 2018-10-31 |
US20120201812A1 (en) | 2012-08-09 |
EP2473527B1 (en) | 2016-11-30 |
EP3438126A1 (en) | 2019-02-06 |
EP3438126B1 (en) | 2020-08-19 |
PT2473528E (pt) | 2015-03-04 |
ES2531083T3 (es) | 2015-03-10 |
US20120244158A1 (en) | 2012-09-27 |
EP3725330A1 (en) | 2020-10-21 |
HRP20190137T1 (hr) | 2019-03-22 |
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