PL2473528T3 - Stabilne formulacje polipeptydów i ich zastosowanie - Google Patents
Stabilne formulacje polipeptydów i ich zastosowanieInfo
- Publication number
- PL2473528T3 PL2473528T3 PL10747896T PL10747896T PL2473528T3 PL 2473528 T3 PL2473528 T3 PL 2473528T3 PL 10747896 T PL10747896 T PL 10747896T PL 10747896 T PL10747896 T PL 10747896T PL 2473528 T3 PL2473528 T3 PL 2473528T3
- Authority
- PL
- Poland
- Prior art keywords
- polypeptides
- stable formulations
- formulations
- stable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27581609P | 2009-09-03 | 2009-09-03 | |
US28450209P | 2009-12-18 | 2009-12-18 | |
PCT/EP2010/062975 WO2011026948A1 (en) | 2009-09-03 | 2010-09-03 | Stable formulations of polypeptides and uses thereof |
EP10747896.8A EP2473528B1 (en) | 2009-09-03 | 2010-09-03 | Stable formulations of polypeptides and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2473528T3 true PL2473528T3 (pl) | 2015-05-29 |
Family
ID=42797362
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL18185772T PL3438126T3 (pl) | 2009-09-03 | 2010-09-03 | Stabilne formulacje polipeptydów i ich zastosowanie |
PL10747896T PL2473528T3 (pl) | 2009-09-03 | 2010-09-03 | Stabilne formulacje polipeptydów i ich zastosowanie |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL18185772T PL3438126T3 (pl) | 2009-09-03 | 2010-09-03 | Stabilne formulacje polipeptydów i ich zastosowanie |
Country Status (12)
Country | Link |
---|---|
US (2) | US20120244158A1 (pl) |
EP (5) | EP2473527B1 (pl) |
CY (1) | CY1121411T1 (pl) |
DK (2) | DK2473528T3 (pl) |
ES (3) | ES2531083T3 (pl) |
HK (1) | HK1204284A1 (pl) |
HR (1) | HRP20190137T1 (pl) |
LT (1) | LT2805731T (pl) |
PL (2) | PL3438126T3 (pl) |
PT (3) | PT2473528E (pl) |
SI (1) | SI2805731T1 (pl) |
WO (2) | WO2011026945A1 (pl) |
Families Citing this family (27)
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JP2010500876A (ja) | 2006-08-18 | 2010-01-14 | アブリンクス エン.ヴェー. | Il−6媒介性シグナル伝達に関連する疾患及び障害の治療のための、il−6rに指向性を有するアミノ酸配列及びこれを含むポリペプチド |
CN101796072B (zh) | 2007-05-24 | 2014-09-24 | 埃博灵克斯股份有限公司 | 用于治疗骨疾病和病症的针对rank-l的氨基酸序列以及包括其的多肽 |
US10118962B2 (en) | 2008-10-29 | 2018-11-06 | Ablynx N.V. | Methods for purification of single domain antigen binding molecules |
CN104740631B (zh) | 2008-10-29 | 2019-04-16 | 阿布林克斯公司 | 单域抗原结合性分子的制剂 |
WO2010100135A1 (en) | 2009-03-05 | 2010-09-10 | Ablynx N.V. | Novel antigen binding dimer-complexes, methods of making/avoiding and uses thereof |
US9265834B2 (en) | 2009-03-05 | 2016-02-23 | Ablynx N.V. | Stable formulations of polypeptides and uses thereof |
EP2417162A2 (en) | 2009-04-10 | 2012-02-15 | Ablynx N.V. | Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders |
WO2010115998A2 (en) | 2009-04-10 | 2010-10-14 | Ablynx Nv | Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders |
EP2473527B1 (en) * | 2009-09-03 | 2016-11-30 | Ablynx N.V. | Stable formulations of polypeptides and uses thereof |
WO2011028962A1 (en) * | 2009-09-04 | 2011-03-10 | Xoma Technology Ltd. | Antibody coformulations |
HUE044292T2 (hu) | 2010-02-11 | 2019-10-28 | Ablynx Nv | Eljárások és készítmények aeroszolok elõállítására |
SI2542257T1 (en) | 2010-03-01 | 2018-01-31 | Bayer Healthcare Llc | Optimized monoclonal antibodies against Tissue Factor Pathway Inhibitor (TFPI) |
WO2011161263A1 (en) | 2010-06-25 | 2011-12-29 | Ablynx Nv | Pharmaceutical compositions for cutaneous administration |
MX349294B (es) * | 2010-12-02 | 2017-07-21 | Oncolytics Biotech Inc | Formulaciones virales liofilizadas. |
CN103347535B (zh) * | 2010-12-02 | 2015-11-25 | 昂科利蒂克斯生物科技公司 | 液体病毒制剂 |
CA2835340A1 (en) | 2011-05-27 | 2012-12-06 | Ablynx Nv | Inhibition of bone resorption with rankl binding peptides |
CN103945862A (zh) * | 2011-07-07 | 2014-07-23 | Lfb美国股份有限公司 | 使蛋白质稳定的制剂 |
US10138302B2 (en) | 2011-09-23 | 2018-11-27 | Ablynx N.V. | Methods for treating rheumatoid arthritis by administering interleukin-6 receptor antibodies |
US9592297B2 (en) | 2012-08-31 | 2017-03-14 | Bayer Healthcare Llc | Antibody and protein formulations |
US20160129112A1 (en) * | 2013-05-28 | 2016-05-12 | Momenta Pharmaceuticals, Inc. | Pharmaceutical Compositions Comprising Pyrophosphate |
EP3209327A1 (en) | 2014-10-21 | 2017-08-30 | Ablynx N.V. | Treatment of il-6r related diseases |
WO2018007442A1 (en) | 2016-07-06 | 2018-01-11 | Ablynx N.V. | Treatment of il-6r related diseases |
WO2018029182A1 (en) | 2016-08-08 | 2018-02-15 | Ablynx N.V. | Il-6r single variable domain antibodies for treatment of il-6r related diseases |
BR112019017853A2 (pt) * | 2017-02-28 | 2021-04-27 | Vib Vzw | Meios e métodos para liberação oral de proteína |
US11261260B2 (en) | 2017-06-02 | 2022-03-01 | Merck Patent Gmbh | ADAMTS binding immunoglobulins |
US11730812B2 (en) * | 2019-03-08 | 2023-08-22 | Boehringer Ingelheim International Gmbh | Anti-IL-36R antibody formulations |
CN114681592A (zh) * | 2020-12-31 | 2022-07-01 | 天境生物科技(杭州)有限公司 | 包含可溶性gp130二聚体的制剂和使用方法 |
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CN104740631B (zh) * | 2008-10-29 | 2019-04-16 | 阿布林克斯公司 | 单域抗原结合性分子的制剂 |
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US9265834B2 (en) | 2009-03-05 | 2016-02-23 | Ablynx N.V. | Stable formulations of polypeptides and uses thereof |
WO2010100135A1 (en) * | 2009-03-05 | 2010-09-10 | Ablynx N.V. | Novel antigen binding dimer-complexes, methods of making/avoiding and uses thereof |
EP2473527B1 (en) * | 2009-09-03 | 2016-11-30 | Ablynx N.V. | Stable formulations of polypeptides and uses thereof |
-
2010
- 2010-09-03 EP EP10747895.0A patent/EP2473527B1/en active Active
- 2010-09-03 EP EP20176028.7A patent/EP3725330A1/en active Pending
- 2010-09-03 PT PT10747896T patent/PT2473528E/pt unknown
- 2010-09-03 DK DK10747896T patent/DK2473528T3/en active
- 2010-09-03 PL PL18185772T patent/PL3438126T3/pl unknown
- 2010-09-03 PT PT107478950T patent/PT2473527T/pt unknown
- 2010-09-03 LT LTEP14171120.0T patent/LT2805731T/lt unknown
- 2010-09-03 US US13/393,636 patent/US20120244158A1/en not_active Abandoned
- 2010-09-03 PL PL10747896T patent/PL2473528T3/pl unknown
- 2010-09-03 DK DK10747895.0T patent/DK2473527T3/en active
- 2010-09-03 EP EP18185772.3A patent/EP3438126B1/en active Active
- 2010-09-03 PT PT181857723T patent/PT3438126T/pt unknown
- 2010-09-03 SI SI201031846T patent/SI2805731T1/sl unknown
- 2010-09-03 EP EP10747896.8A patent/EP2473528B1/en active Active
- 2010-09-03 ES ES10747896T patent/ES2531083T3/es active Active
- 2010-09-03 ES ES10747895.0T patent/ES2617180T3/es active Active
- 2010-09-03 EP EP14171120.0A patent/EP2805731B1/en active Active
- 2010-09-03 WO PCT/EP2010/062972 patent/WO2011026945A1/en active Application Filing
- 2010-09-03 US US13/393,679 patent/US9884117B2/en active Active
- 2010-09-03 ES ES18185772T patent/ES2831323T3/es active Active
- 2010-09-03 WO PCT/EP2010/062975 patent/WO2011026948A1/en active Application Filing
-
2015
- 2015-05-22 HK HK15104885.3A patent/HK1204284A1/xx not_active IP Right Cessation
-
2019
- 2019-01-21 HR HRP20190137TT patent/HRP20190137T1/hr unknown
- 2019-01-31 CY CY20191100137T patent/CY1121411T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
US20120201812A1 (en) | 2012-08-09 |
HRP20190137T1 (hr) | 2019-03-22 |
ES2617180T3 (es) | 2017-06-15 |
WO2011026948A1 (en) | 2011-03-10 |
EP2473527B1 (en) | 2016-11-30 |
WO2011026945A1 (en) | 2011-03-10 |
EP2473528B1 (en) | 2014-12-03 |
DK2473528T3 (en) | 2015-03-02 |
US9884117B2 (en) | 2018-02-06 |
DK2473527T3 (en) | 2017-03-06 |
SI2805731T1 (sl) | 2019-02-28 |
PL3438126T3 (pl) | 2021-03-08 |
EP2805731A2 (en) | 2014-11-26 |
EP2473527A1 (en) | 2012-07-11 |
EP2805731B1 (en) | 2018-10-31 |
ES2831323T3 (es) | 2021-06-08 |
CY1121411T1 (el) | 2020-05-29 |
LT2805731T (lt) | 2019-02-11 |
PT2473527T (pt) | 2017-02-27 |
EP3438126A1 (en) | 2019-02-06 |
EP3438126B1 (en) | 2020-08-19 |
PT3438126T (pt) | 2020-11-09 |
EP2473528A1 (en) | 2012-07-11 |
US20120244158A1 (en) | 2012-09-27 |
HK1204284A1 (en) | 2015-11-13 |
PT2473528E (pt) | 2015-03-04 |
EP3725330A1 (en) | 2020-10-21 |
ES2531083T3 (es) | 2015-03-10 |
EP2805731A3 (en) | 2015-04-01 |
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