SI2805731T1 - Stabilne formulacije polipeptidov in njihove uporabe - Google Patents

Stabilne formulacije polipeptidov in njihove uporabe

Info

Publication number
SI2805731T1
SI2805731T1 SI201031846T SI201031846T SI2805731T1 SI 2805731 T1 SI2805731 T1 SI 2805731T1 SI 201031846 T SI201031846 T SI 201031846T SI 201031846 T SI201031846 T SI 201031846T SI 2805731 T1 SI2805731 T1 SI 2805731T1
Authority
SI
Slovenia
Prior art keywords
polypeptides
stable formulations
formulations
stable
Prior art date
Application number
SI201031846T
Other languages
English (en)
Inventor
Ann Brige
Christine Labeur
Brabandere Veronique De
Original Assignee
Ablynx N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ablynx N.V. filed Critical Ablynx N.V.
Publication of SI2805731T1 publication Critical patent/SI2805731T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
SI201031846T 2009-09-03 2010-09-03 Stabilne formulacije polipeptidov in njihove uporabe SI2805731T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27581609P 2009-09-03 2009-09-03
US28450209P 2009-12-18 2009-12-18
EP14171120.0A EP2805731B1 (en) 2009-09-03 2010-09-03 Stable formulations of polypeptides and uses thereof

Publications (1)

Publication Number Publication Date
SI2805731T1 true SI2805731T1 (sl) 2019-02-28

Family

ID=42797362

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201031846T SI2805731T1 (sl) 2009-09-03 2010-09-03 Stabilne formulacije polipeptidov in njihove uporabe

Country Status (12)

Country Link
US (2) US9884117B2 (sl)
EP (5) EP2805731B1 (sl)
CY (1) CY1121411T1 (sl)
DK (2) DK2473527T3 (sl)
ES (3) ES2531083T3 (sl)
HK (1) HK1204284A1 (sl)
HR (1) HRP20190137T1 (sl)
LT (1) LT2805731T (sl)
PL (2) PL2473528T3 (sl)
PT (3) PT2473527T (sl)
SI (1) SI2805731T1 (sl)
WO (2) WO2011026945A1 (sl)

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Also Published As

Publication number Publication date
CY1121411T1 (el) 2020-05-29
EP2805731A3 (en) 2015-04-01
EP2805731B1 (en) 2018-10-31
PL3438126T3 (pl) 2021-03-08
EP3725330A1 (en) 2020-10-21
WO2011026945A1 (en) 2011-03-10
PL2473528T3 (pl) 2015-05-29
LT2805731T (lt) 2019-02-11
PT2473528E (pt) 2015-03-04
EP2473528A1 (en) 2012-07-11
EP2473527A1 (en) 2012-07-11
DK2473527T3 (en) 2017-03-06
WO2011026948A1 (en) 2011-03-10
PT2473527T (pt) 2017-02-27
PT3438126T (pt) 2020-11-09
EP2473527B1 (en) 2016-11-30
US20120201812A1 (en) 2012-08-09
EP2473528B1 (en) 2014-12-03
ES2617180T3 (es) 2017-06-15
ES2531083T3 (es) 2015-03-10
DK2473528T3 (en) 2015-03-02
US20120244158A1 (en) 2012-09-27
US9884117B2 (en) 2018-02-06
EP2805731A2 (en) 2014-11-26
EP3438126A1 (en) 2019-02-06
EP3438126B1 (en) 2020-08-19
HRP20190137T1 (hr) 2019-03-22
HK1204284A1 (en) 2015-11-13
ES2831323T3 (es) 2021-06-08

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