PL204737B1
(pl)
|
2000-12-13 |
2010-02-26 |
Unilever Nv |
Sposób wytwarzania heterologicznego białka przez grzyby
|
US20040018197A1
(en)
*
|
2002-04-26 |
2004-01-29 |
Promega Corporation |
Treatment for weight loss
|
EP2267032A3
(de)
|
2002-11-08 |
2011-11-09 |
Ablynx N.V. |
Verfahren zur Verabreichung therapeutischer Polypeptide und Polypeptide dafür
|
US20060034845A1
(en)
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
WO2004041862A2
(en)
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
CN101724071A
(zh)
|
2004-10-08 |
2010-06-09 |
杜门蒂斯有限公司 |
抗肿瘤坏死因子受体1的单域抗体及其使用方法
|
EP1814514A2
(de)
*
|
2004-11-25 |
2007-08-08 |
Unilever Naamloze Vennootschap |
Schwerketten- und einzeldomänen-antikörper
|
WO2006122787A1
(en)
|
2005-05-18 |
2006-11-23 |
Ablynx Nv |
Serum albumin binding proteins
|
KR101414438B1
(ko)
|
2005-05-20 |
2014-07-10 |
아블린쓰 엔.브이. |
폰 빌레브란트 인자에 대한 단일 도메인 vhh 항체
|
EP3028716B1
(de)
|
2006-10-10 |
2020-09-16 |
Regenesance B.V. |
Komplementhemmung für verbesserte nervenregeneration
|
GB0621513D0
(en)
|
2006-10-30 |
2006-12-06 |
Domantis Ltd |
Novel polypeptides and uses thereof
|
WO2008074840A2
(en)
|
2006-12-19 |
2008-06-26 |
Ablynx N.V. |
Amino acid sequences directed against a metalloproteinase from the adam family and polypeptides comprising the same for the treatment of adam-related diseases and disorders
|
EP2557090A3
(de)
|
2006-12-19 |
2013-05-29 |
Ablynx N.V. |
Gegen GPCRs gerichtete Aminosäuresequenzen und Polypeptide damit zur Behandlung von Krankheiten und Störungen im Zusammenhang mit GPCR
|
WO2008118013A2
(en)
|
2007-03-23 |
2008-10-02 |
To-Bbb Holding B.V. |
Targeted intracellular delivery of antiviral agents
|
CA2691940C
(en)
|
2007-07-03 |
2018-03-06 |
Joost Alexander Kolkman |
Methods for providing improved immunoglobulin sequences
|
BRPI0819656A2
(pt)
|
2007-11-27 |
2015-06-23 |
Ablynx Nv |
Seqüências de aminoácidos contras citocinas heterodiméricas e/ou seus receptores e polipeptídeos compreendendo as mesmas
|
WO2009109572A2
(en)
*
|
2008-03-03 |
2009-09-11 |
Ablynx Nv |
Monovalent phage display of single variable domains
|
EP2247616A2
(de)
|
2008-03-05 |
2010-11-10 |
Ablynx N.V. |
Neuartige antigenbindende dimerkomplexe, verfahren zu ihrer herstellung und verwendungen davon
|
EP2260058A2
(de)
|
2008-04-07 |
2010-12-15 |
Ablynx N.V. |
Variable einzeldomänen gegen notch-signalwege
|
US8217140B2
(en)
|
2008-04-17 |
2012-07-10 |
Ablynx N.V. |
Peptides capable of binding to serum proteins and compounds, constructs and polypeptides comprising the same
|
EP2403873A1
(de)
|
2009-03-05 |
2012-01-11 |
Ablynx N.V. |
Neue antigenbindende dimerkomplexe, verfahren zur herstellung/vermeidung und anwendungen davon
|
EP2982690B1
(de)
|
2009-04-30 |
2021-01-27 |
Ablynx N.V. |
Verfahren zur herstellung von domänen-antikörpern
|
HUE051430T2
(hu)
|
2009-07-10 |
2021-03-01 |
Ablynx Nv |
Eljárás variábilis domének elõállítására
|
EP3438126B1
(de)
|
2009-09-03 |
2020-08-19 |
Ablynx N.V. |
Stabile formulierungen aus polypeptiden und verwendungen davon
|
WO2011083141A2
(en)
|
2010-01-08 |
2011-07-14 |
Ablynx Nv |
Method for generation of immunoglobulin sequences by using lipoprotein particles
|
EP2531523A1
(de)
|
2010-02-05 |
2012-12-12 |
Ablynx N.V. |
An serumalbumin bindende peptide und verbindungen, konstrukte und polypeptide damit
|
PL2533761T3
(pl)
|
2010-02-11 |
2019-09-30 |
Ablynx N.V. |
Sposoby i kompozycje do wytwarzania aerozoli
|
US9556273B2
(en)
*
|
2010-03-29 |
2017-01-31 |
Vib Vzw |
Anti-macrophage mannose receptor single variable domains for targeting and in vivo imaging of tumor-associated macrophages
|
US9101674B2
(en)
|
2010-03-29 |
2015-08-11 |
Vib Vzw |
Targeting and in vivo imaging of tumor-associated macrophages
|
WO2011161263A1
(en)
|
2010-06-25 |
2011-12-29 |
Ablynx Nv |
Pharmaceutical compositions for cutaneous administration
|
AU2011293127B2
(en)
*
|
2010-08-27 |
2016-05-12 |
Abbvie Stemcentrx Llc |
Notum protein modulators and methods of use
|
WO2012056000A1
(en)
|
2010-10-29 |
2012-05-03 |
Ablynx Nv |
Method for the production of immunoglobulin single variable domains
|
PT2691415T
(pt)
|
2011-03-28 |
2018-10-19 |
Ablynx Nv |
Método para produção de formulações sólidas compreendendo domínios variáveis únicos de imunoglobulina
|
EP2707382B1
(de)
|
2011-05-09 |
2019-07-17 |
Ablynx NV |
Verfahren zur herstellung von variablen immunglobulin-einzeldomänen
|
RU2661677C2
(ru)
|
2011-05-27 |
2018-07-18 |
Аблинкс Нв |
Ингибирование резорбции кости с помощью связывающих rank-l пептидов
|
CN104271598A
(zh)
|
2011-06-23 |
2015-01-07 |
埃博灵克斯股份有限公司 |
针对IgE的免疫球蛋白单可变结构域
|
EP3311837A1
(de)
|
2011-09-23 |
2018-04-25 |
Ablynx NV |
Verlängerte hemmung der interleukin-6-vermittelten signalisierung
|
JP6411333B2
(ja)
|
2012-05-24 |
2018-10-24 |
ブイアイビー ブイゼットダブリュVib Vzw |
腫瘍関連マクロファージのターゲティングおよびinvivoイメージング用抗マクロファージマンノース受容体単一可変ドメイン
|
WO2014087010A1
(en)
|
2012-12-07 |
2014-06-12 |
Ablynx N.V. |
IMPROVED POLYPEPTIDES DIRECTED AGAINST IgE
|
JP6443344B2
(ja)
|
2013-01-30 |
2018-12-26 |
フエー・イー・ベー・フエー・ゼツト・ウエー |
スクリーニングおよび薬物開発のための新規キメラポリペプチド
|
PT2953973T
(pt)
|
2013-02-05 |
2019-10-25 |
Univ Brussel Vrije |
Agentes de ligação do receptor muscarínico de acetilololina e usos
|
CA2906259C
(en)
|
2013-03-15 |
2022-12-06 |
Vib Vzw |
Anti-mmr single variable domains for prognosis and monitoring of cardiovascular diseases
|
PL2992101T3
(pl)
|
2013-04-29 |
2019-05-31 |
Agrosavfe Nv |
Kompozycje agrochemiczne zawierające przeciwciała wiążące się ze sfingolipidami
|
NL1040254C2
(en)
|
2013-05-17 |
2014-11-24 |
Ablynx Nv |
Stable formulations of immunoglobulin single variable domains and uses thereof.
|
EP2883883A1
(de)
|
2013-12-16 |
2015-06-17 |
Cardio3 Biosciences S.A. |
Therapeutische Ziele und Mittel zur Behandlung von ischämiebedingten Reperfusionsschäden
|
AU2015217846B2
(en)
|
2014-01-30 |
2019-10-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
Opioid receptor binding agents and uses thereof
|
NL2013661B1
(en)
|
2014-10-21 |
2016-10-05 |
Ablynx Nv |
KV1.3 Binding immunoglobulins.
|
EP3718574A1
(de)
|
2014-07-29 |
2020-10-07 |
Vrije Universiteit Brussel |
Radioaktiv markierte antikörperfragmente zur verwendung bei der vorbeugung und/oder behandlung von krebs
|
US20180036442A1
(en)
|
2014-07-29 |
2018-02-08 |
Vrije Universiteit Brussel |
Radio-labelled antibody fragments for use in the prognosis, diagnosis of cancer as well as for the prediction of cancer therapy response
|
EP3215624B1
(de)
|
2014-11-05 |
2023-11-29 |
Biotalys NV |
Transgene pflanzen mit einem für die variable domäne eines schwerkettigen antikörpers codierendem polynukleotid
|
WO2016097313A1
(en)
|
2014-12-19 |
2016-06-23 |
Ablynx N.V. |
Cysteine linked nanobody dimers
|
JP6917357B2
(ja)
|
2015-07-17 |
2021-08-11 |
フレイエ ユニヴェルシテイト ブリュッセルVrije Universiteit Brussel |
癌治療に使用する放射標識抗体断片
|
SG11201803976VA
(en)
|
2015-11-27 |
2018-06-28 |
Ablynx Nv |
Polypeptides inhibiting cd40l
|
US11243214B2
(en)
|
2016-04-22 |
2022-02-08 |
Université Libre de Bruxelles |
Biomarker expressed in pancreatic beta cells useful in imaging or targeting beta cells
|
WO2017182605A1
(en)
|
2016-04-22 |
2017-10-26 |
Université Libre de Bruxelles |
A new biomarker expressed in pancreatic beta cells useful in imaging or targeting beta cells
|
CN109311968A
(zh)
|
2016-05-02 |
2019-02-05 |
埃博灵克斯股份有限公司 |
治疗rsv感染
|
WO2018007442A1
(en)
|
2016-07-06 |
2018-01-11 |
Ablynx N.V. |
Treatment of il-6r related diseases
|
WO2018029182A1
(en)
|
2016-08-08 |
2018-02-15 |
Ablynx N.V. |
Il-6r single variable domain antibodies for treatment of il-6r related diseases
|
US11098113B2
(en)
|
2016-09-15 |
2021-08-24 |
Vib Vzw |
Immunoglobulin single variable domains directed against macrophage migration inhibitory factor
|
WO2018091606A1
(en)
|
2016-11-16 |
2018-05-24 |
Ablynx Nv |
T cell recruiting polypeptides capable of binding cd123 and tcr alpha/beta
|
WO2018099968A1
(en)
|
2016-11-29 |
2018-06-07 |
Ablynx N.V. |
Treatment of infection by respiratory syncytial virus (rsv)
|
EP3589725A1
(de)
|
2017-02-28 |
2020-01-08 |
Vib Vzw |
Mittel und verfahren zur oralen proteinabgabe
|
CA3058290A1
(en)
|
2017-04-18 |
2018-10-25 |
Universite Libre De Bruxelles |
Biomarkers and targets for proliferative diseases
|
KR20200005635A
(ko)
|
2017-05-11 |
2020-01-15 |
브이아이비 브이지더블유 |
가변 면역글로불린 도메인의 글리코실화
|
EP3630847A1
(de)
|
2017-06-02 |
2020-04-08 |
Merck Patent GmbH |
Adamts-bindende immunoglobuline
|
KR20200013247A
(ko)
|
2017-06-02 |
2020-02-06 |
아블린쓰 엔.브이. |
아그레칸 결합 면역글로불린
|
BR112019025097A2
(pt)
|
2017-06-02 |
2020-07-28 |
Merck Patent Gmbh |
imunoglobulinas de ligação a mmp13
|
JP7249961B2
(ja)
|
2017-06-02 |
2023-03-31 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Adamts5、mmp13およびアグリカンに結合するポリペプチド
|
WO2019016237A1
(en)
|
2017-07-19 |
2019-01-24 |
Vib Vzw |
AGENTS FOR CONNECTING TO SERUM ALBUMIN
|
WO2019086548A1
(en)
|
2017-10-31 |
2019-05-09 |
Vib Vzw |
Novel antigen-binding chimeric proteins and methods and uses thereof
|
WO2019155041A1
(en)
|
2018-02-12 |
2019-08-15 |
Vib Vzw |
Gβγ COMPLEX ANTIBODIES AND USES THEREOF
|
CA3092421A1
(en)
|
2018-03-01 |
2019-09-06 |
Vrije Universiteit Brussel |
Human pd-l1-binding immunoglobulins
|
EP4163295A1
(de)
|
2018-03-23 |
2023-04-12 |
Université Libre de Bruxelles |
Agonistenmoleküle des wnt-signalwegs
|
MX2020010091A
(es)
|
2018-03-27 |
2021-01-15 |
Umc Utrecht Holding Bv |
Trombolisis direccionada para tratamiento de trombosis microvascular.
|
CA3138028A1
(en)
|
2019-04-29 |
2020-11-05 |
Confo Therapeutics N.V. |
Chimeric proteins and methods to screen for compounds and ligands binding to gpcrs
|
US20220289837A1
(en)
|
2019-04-30 |
2022-09-15 |
Vib Vzw |
Cystic Fibrosis Transmembrane Conductance Regulator Stabilizing Agents
|
EP3976650A1
(de)
|
2019-05-28 |
2022-04-06 |
Vib Vzw |
Krebsbehandlung durch abzielen auf plexine im immunbereich
|
US20220228116A1
(en)
|
2019-05-28 |
2022-07-21 |
Vib Vzw |
Cd8+ t-cells lacking plexins and their application in cancer treatment
|
US20220380456A1
(en)
|
2019-10-21 |
2022-12-01 |
Vib Vzw |
Nanodisc-specific antigen-binding chimeric proteins
|
CA3160506A1
(en)
|
2019-11-11 |
2021-05-20 |
Ibi-Ag Innovative Bio Insecticides Ltd. |
Insect control nanobodies and uses thereof
|
EP4065603A1
(de)
|
2019-11-27 |
2022-10-05 |
Vib Vzw |
Positive allosterische modulatoren des calciumempfindlichen rezeptors
|
GB201918279D0
(en)
|
2019-12-12 |
2020-01-29 |
Vib Vzw |
Glycosylated single chain immunoglobulin domains
|
EP4077372A1
(de)
|
2019-12-20 |
2022-10-26 |
Vib Vzw |
Nanokörperaustauschchromatographie
|
WO2021140205A1
(en)
|
2020-01-10 |
2021-07-15 |
Confo Therapeutics N.V. |
Methods for generating antibodies and antibody fragments and libraries comprising same
|
WO2021156490A2
(en)
|
2020-02-06 |
2021-08-12 |
Vib Vzw |
Corona virus binders
|
WO2021170540A1
(en)
|
2020-02-25 |
2021-09-02 |
Vib Vzw |
Leucine-rich repeat kinase 2 allosteric modulators
|
US20230110053A1
(en)
|
2020-03-31 |
2023-04-13 |
Biotalys NV |
Anti-fungal polypeptides
|
EP4144758A4
(de)
|
2020-04-22 |
2024-05-15 |
Mabwell Shanghai Bioscience Co Ltd |
Gegen den humanen liganden 1 für programmierten zelltod (pd-l1) gerichteter einzelvariabler domänenantikörper und derivat davon
|
WO2021229104A1
(en)
|
2020-05-15 |
2021-11-18 |
Université de Liège |
Anti-cd38 single-domain antibodies in disease monitoring and treatment
|
WO2022003156A1
(en)
|
2020-07-02 |
2022-01-06 |
Oncurious Nv |
Ccr8 non-blocking binders
|
AU2021319024A1
(en)
|
2020-07-31 |
2023-03-23 |
Biotalys NV |
Expression host
|
WO2022063957A1
(en)
|
2020-09-24 |
2022-03-31 |
Vib Vzw |
Biomarker for anti-tumor therapy
|
US20230364049A1
(en)
|
2020-09-24 |
2023-11-16 |
Vib Vzw |
Combination of p2y6 inhibitors and immune checkpoint inhibitors
|
US20220153854A1
(en)
|
2020-09-25 |
2022-05-19 |
Ablynx N.V. |
Polypeptides comprising immunoglobulin single variable domains targeting il-13 and ox40l
|
WO2022117569A1
(en)
|
2020-12-02 |
2022-06-09 |
Oncurious Nv |
A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer
|
JP2024508207A
(ja)
|
2020-12-02 |
2024-02-26 |
ブイアイビー ブイゼットダブリュ |
がんに対する組み合わせ治療におけるltbrアゴニスト
|
TW202239763A
(zh)
|
2020-12-18 |
2022-10-16 |
比利時商艾伯霖克斯公司 |
包含靶向IL-6和TNF-α的免疫球蛋白單可變結構域的多肽
|
GB202020502D0
(en)
|
2020-12-23 |
2021-02-03 |
Vib Vzw |
Antibody composistion for treatment of corona virus infection
|
CA3206124A1
(en)
|
2020-12-24 |
2022-06-30 |
Vib Vzw |
Non-blocking human ccr8 binders
|
WO2022136647A1
(en)
|
2020-12-24 |
2022-06-30 |
Oncurious Nv |
Human ccr8 binders
|
EP4267621A1
(de)
|
2020-12-24 |
2023-11-01 |
Vib Vzw |
Kreuzreaktive menschliche ccr8-bindemittel aus der maus
|
CN117794566A
(zh)
|
2021-02-05 |
2024-03-29 |
Vib研究所 |
沙贝病毒结合剂
|
EP4288095A1
(de)
|
2021-02-05 |
2023-12-13 |
Vib Vzw |
Sarbecovirus-bindemittel
|
CA3211257A1
(en)
|
2021-02-17 |
2022-08-25 |
Vib Vzw |
Inhibition of slc4a4 in the treatment of cancer
|
EP4294516A1
(de)
|
2021-02-19 |
2023-12-27 |
Vib Vzw |
Kationunabhängige mannose-6-phosphatrezeptorbindemittel
|
WO2022199804A1
(en)
|
2021-03-24 |
2022-09-29 |
Vib Vzw |
Nek6 inhibition to treat als and ftd
|
WO2022242892A1
(en)
|
2021-05-17 |
2022-11-24 |
Université de Liège |
Anti-cd38 single-domain antibodies in disease monitoring and treatment
|
WO2022268993A1
(en)
|
2021-06-23 |
2022-12-29 |
Vib Vzw |
Means and methods for selection of specific binders
|
CN117580865A
(zh)
|
2021-06-29 |
2024-02-20 |
山东先声生物制药有限公司 |
Cd16抗体及其应用
|
WO2023016828A2
(en)
|
2021-07-30 |
2023-02-16 |
Vib Vzw |
Cation-independent mannose-6-phosphate receptor binders for targeted protein degradation
|
AU2022320667A1
(en)
|
2021-07-30 |
2024-03-14 |
Shandong Simcere Biopharmaceutical Co., Ltd. |
Anti-pvrig/anti-tigit bispecific antibody and application
|
WO2023057601A1
(en)
|
2021-10-06 |
2023-04-13 |
Biotalys NV |
Anti-fungal polypeptides
|
TW202342508A
(zh)
|
2021-12-17 |
2023-11-01 |
比利時商艾伯霖克斯公司 |
包含靶向TCRαβ、CD33和CD123的免疫球蛋白單可變結構域的多肽
|
WO2023135198A1
(en)
|
2022-01-12 |
2023-07-20 |
Vib Vzw |
Human ntcp binders for therapeutic use and liver-specific targeted delivery
|
WO2023148291A1
(en)
|
2022-02-02 |
2023-08-10 |
Biotalys NV |
Methods for genome editing
|
WO2023148397A1
(en)
|
2022-02-07 |
2023-08-10 |
Vib Vzw |
Engineered stabilizing aglycosylated fc-regions
|
WO2023198848A1
(en)
|
2022-04-13 |
2023-10-19 |
Vib Vzw |
An ltbr agonist in combination therapy against cancer
|
WO2023213751A1
(en)
|
2022-05-02 |
2023-11-09 |
Umc Utrecht Holding B.V |
Single domain antibodies for the detection of plasmin-cleaved vwf
|
WO2023222825A1
(en)
|
2022-05-18 |
2023-11-23 |
Vib Vzw |
Sarbecovirus spike s2 subunit binders
|
WO2024008755A1
(en)
|
2022-07-04 |
2024-01-11 |
Vib Vzw |
Blood-cerebrospinal fluid barrier crossing antibodies
|
WO2024068744A1
(en)
|
2022-09-27 |
2024-04-04 |
Vib Vzw |
Antivirals against human parainfluenza virus
|
WO2024105091A1
(en)
|
2022-11-15 |
2024-05-23 |
Imec Vzw |
Method and system for droplet manipulation
|