AR102550A1 - Planta transgénica que comprende un polinucleótido que codifica un dominio variable de anticuerpo de cadena pesada - Google Patents

Planta transgénica que comprende un polinucleótido que codifica un dominio variable de anticuerpo de cadena pesada

Info

Publication number
AR102550A1
AR102550A1 ARP150103596A ARP150103596A AR102550A1 AR 102550 A1 AR102550 A1 AR 102550A1 AR P150103596 A ARP150103596 A AR P150103596A AR P150103596 A ARP150103596 A AR P150103596A AR 102550 A1 AR102550 A1 AR 102550A1
Authority
AR
Argentina
Prior art keywords
plant
tissue
cell
pathogen
heavy chain
Prior art date
Application number
ARP150103596A
Other languages
English (en)
Inventor
Elodie Van Daele Inge
Peferoen Marnix
Filipe Veloso Vieira Joo
Geerinck Jan
Verheesen Peter
Original Assignee
Agrosavfe Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agrosavfe Nv filed Critical Agrosavfe Nv
Publication of AR102550A1 publication Critical patent/AR102550A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8282—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/14—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from fungi, algea or lichens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Cultivation Of Plants (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Reivindicación 1: Una planta o tejido vegetal o célula vegetal transgénico que comprende al menos un polinucleótido que comprende al menos una secuencia que codifica para un dominio variable de un anticuerpo de cadena pesada (VHH) que se une específicamente a un esfingolípido de un hongo, preferiblemente a una ceramida de un hongo, más preferiblemente a un glicoesfingolípido de un hongo, incluso más preferiblemente a un cerebrósido de un hongo, aún más preferiblemente a un glucocerebrósido de un hongo. Reivindicación 8: Partes cosechables y materiales de propagación de una planta o tejido vegetal o célula vegetal transgénico de acuerdo con una cualquiera de las reivindicaciones 1 a 7, que comprende al menos un polinucleótido como se lo define en una cualquiera de las reivindicaciones 1 a 7. Reivindicación 11: Un método para proteger al menos parte de una planta o tejido vegetal o célula vegetal de una infección con un patógeno de planta, para inhibir el crecimiento de un patógeno de planta en al menos parte de una planta o tejido vegetal o célula vegetal, y/o para incrementar la resistencia a patógenos de al menos parte de una planta o tejido vegetal o célula vegetal, que comprende expresar en al menos parte de la planta o tejido vegetal o célula vegetal al menos un polinucleótido que codifica un dominio variable de un anticuerpo de cadena pesada (VHH) que se une específicamente a un patógeno. Reivindicación 13: Uso de al menos un polinucleótido que codifica un dominio variable de un anticuerpo de cadena pesada (VHH) que se une específicamente a un patógeno, para proteger al menos parte de una planta o tejido vegetal o célula vegetal de una infección con un patógeno de planta, para inhibir el crecimiento de un patógeno de planta en al menos parte de una planta o tejido vegetal o célula vegetal, y/o para incrementar la resistencia a patógenos de al menos parte de una planta o tejido vegetal o célula vegetal, en donde el polinucleótido es expresado en al menos parte de la planta o tejido vegetal.
ARP150103596A 2014-11-05 2015-11-05 Planta transgénica que comprende un polinucleótido que codifica un dominio variable de anticuerpo de cadena pesada AR102550A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14191959 2014-11-05

Publications (1)

Publication Number Publication Date
AR102550A1 true AR102550A1 (es) 2017-03-08

Family

ID=51845355

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP150103596A AR102550A1 (es) 2014-11-05 2015-11-05 Planta transgénica que comprende un polinucleótido que codifica un dominio variable de anticuerpo de cadena pesada

Country Status (7)

Country Link
US (2) US10858666B2 (es)
EP (1) EP3215624B1 (es)
JP (2) JP7089877B2 (es)
AR (1) AR102550A1 (es)
BR (1) BR112017009330A2 (es)
CA (1) CA2966548A1 (es)
WO (1) WO2016071438A2 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160145325A1 (en) 2013-04-29 2016-05-26 Agrosavfe N.V. Agrochemical compositions comprising antibodies binding to sphingolipids
US20180222966A1 (en) * 2013-04-29 2018-08-09 Agrosavfe N.V. Transgenic plant comprising a polynucleotide encoding a variable domain of heavy-chain antibody
CA2966548A1 (en) 2014-11-05 2016-05-12 Agrosavfe Nv Transgenic plant comprising a polynucleotide encoding a variable domain of heavy-chain antibody
US10017560B1 (en) 2017-11-16 2018-07-10 King Saud University Nanobody against begomoviruses
WO2019161386A1 (en) * 2018-02-19 2019-08-22 New York University Alpha-synuclein single domain antibodies
AU2021250446A1 (en) 2020-03-31 2022-11-17 Biotalys NV Anti-fungal polypeptides
CN113080114A (zh) * 2021-04-12 2021-07-09 浙江大学 一种提高鱼类子代成活率的方法
WO2023057601A1 (en) * 2021-10-06 2023-04-13 Biotalys NV Anti-fungal polypeptides
EP4170039A1 (en) * 2021-10-22 2023-04-26 The Sainsbury Laboratory Modifying the immune response in plants
WO2024118831A1 (en) * 2022-11-30 2024-06-06 Velozbio Company Compositions and methods for protein production
WO2024145551A1 (en) * 2022-12-29 2024-07-04 Biotalys NV Agrochemical compositions

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2052027T5 (es) 1988-11-11 2005-04-16 Medical Research Council Clonacion de secuencias de dominio variable de inmunoglobulina.
EP1087013B1 (en) 1992-08-21 2009-01-07 Vrije Universiteit Brussel Immunoglobulins devoid of light chains
ES2162863T3 (es) 1993-04-29 2002-01-16 Unilever Nv Produccion de anticuerpos o fragmentos (funcionalizados) de los mismos derivados de inmunoglobulinas de cadena pesada de camelidae.
FR2708622B1 (fr) 1993-08-02 1997-04-18 Raymond Hamers Vecteur recombinant contenant une séquence d'un gène de lipoprotéine de structure pour l'expression de séquences de nucléotides.
JPH10506274A (ja) * 1994-09-19 1998-06-23 リークスラントボウユニフエルジタイト・ワゲニンゲン 農作物保護剤をコードする遺伝子構築物、ならびにそうした構築物を含有しかつ発現する形質転換された植物、ならびに農作物における病害生物体（ｐｌａｇｕｅ ｏｒｇａｎｉｓｍｓ）および病原体の調節方法
EP0739981A1 (en) 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
ES2294799T3 (es) 1996-06-27 2008-04-01 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. Moleculas de anticuerpos que interactuan especificamente con el sitio activo o hendidura de una molecula diana.
AU3596599A (en) 1998-01-26 1999-08-09 Unilever Plc Method for producing antibody fragments
WO2000002996A2 (en) 1998-07-10 2000-01-20 Cornell Research Foundation, Inc. Recombinant constructs and systems for secretion of proteins via type iii secretion systems
CA2345903C (en) 1998-10-16 2006-09-26 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Molecular pathogenicide mediated plant disease resistance
AU3041100A (en) 1999-01-05 2000-07-24 Unilever Plc Binding of antibody fragments to solid supports
EP1144616B2 (en) 1999-01-19 2009-01-14 Unilever Plc Method for producing antibody fragments
AU776824B2 (en) 1999-04-22 2004-09-23 Unilever Plc Inhibition of viral infection using monovalent antigen-binding proteins
ATE480140T1 (de) 1999-07-22 2010-09-15 Nat Inst Of Agrobio Sciences Verfahren zur superschnellen transformation von monokotyledonen
US6479280B1 (en) 1999-09-24 2002-11-12 Vlaams Interuniversitair Institutuut Voor Biotechnologie Vzw Recombinant phages capable of entering host cells via specific interaction with an artificial receptor
WO2001044301A1 (en) 1999-11-29 2001-06-21 Unilever Plc Immobilized single domain antigen-binding molecules
WO2001040310A2 (en) 1999-11-29 2001-06-07 Unilever Plc Immobilisation of proteins using a polypeptide segment
EP1118669A3 (en) 1999-12-17 2001-08-29 Unilever Plc Production of camelid antibodies in plants
ES2324280T3 (es) 2000-03-14 2009-08-04 Unilever N.V. Dominios variables de la cadena pesada de anticuerpos frente a lipasas dieteticas humanas y sus usos.
CA2380443C (en) 2000-05-26 2013-03-12 Ginette Dubuc Single-domain antigen-binding antibody fragments derived from llama antibodies
WO2002048193A2 (en) 2000-12-13 2002-06-20 Unilever N.V. Camelidae antibody arrays
US20060073141A1 (en) 2001-06-28 2006-04-06 Domantis Limited Compositions and methods for treating inflammatory disorders
EP1433793A4 (en) 2001-09-13 2006-01-25 Inst Antibodies Co Ltd METHOD FOR CREATING A CAMEL ANTIBODY LIBRARY
JP2005289809A (ja) 2001-10-24 2005-10-20 Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) 突然変異重鎖抗体
US20050214857A1 (en) 2001-12-11 2005-09-29 Algonomics N.V. Method for displaying loops from immunoglobulin domains in different contexts
WO2003054016A2 (en) 2001-12-21 2003-07-03 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Method for cloning of variable domain sequences
EP1461085A2 (en) 2002-01-03 2004-09-29 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Immunoconjugates useful for treatment of tumours
EP1497333A2 (en) * 2002-04-22 2005-01-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Antibodies, recombinant antibodies, recombinant antibody fragments and fusions mediated plant disease resistance against fungi
DE10234116A1 (de) 2002-07-26 2004-02-12 Land Rheinland-Pfalz vertreten durch die Staatliche Lehr- und Forschungsanstalt für Landwirtschaft, Weinbau und Gartenbau (SLFA) Verfahren zur Expression von gegen virale Proteine gerichtete scFv-Fragmenten in Pflanzen und deren Verwendung
EP2267032A3 (en) 2002-11-08 2011-11-09 Ablynx N.V. Method of administering therapeutic polypeptides, and polypeptides therefor
NZ540194A (en) 2002-11-08 2008-07-31 Ablynx Nv Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
JP2006517789A (ja) 2003-01-10 2006-08-03 アブリンクス エン．ヴェー． 治療用ポリペプチド、その相同物、その断片、および血小板媒介凝集の調節での使用
JP4283127B2 (ja) 2003-06-20 2009-06-24 独立行政法人科学技術振興機構 転写因子を転写抑制因子に変換するペプチド及びこれをコードするポリヌクレオチド、並びにその利用
US7563443B2 (en) 2004-09-17 2009-07-21 Domantis Limited Monovalent anti-CD40L antibody polypeptides and compositions thereof
MX2009011287A (es) 2007-04-20 2010-02-18 Hexima Ltd Defensina de planta modificada.
NZ580505A (en) * 2007-04-20 2011-03-31 Hexima Ltd Modified plant defensin comprising a signal peptide, a mature domain from a Class I defensin and a C-terminal propeptide tail from a Class II plant defensin
CU23688A1 (es) * 2008-03-28 2011-07-11 Ct Ingenieria Genetica Biotech Secuencias de ácido nucleico y aminoácidos para el control de agentes patógenos
WO2010019442A1 (en) * 2008-08-12 2010-02-18 Plant Health Care, Inc. Production, formulation, and uses of stable liquid harpin protein formulations
EP2367840B1 (en) 2008-12-08 2015-08-12 Complix N.V. Single-chain antiparallel coiled coil proteins
AU2010288743A1 (en) 2009-08-24 2011-09-01 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Antibody fusion-mediated plant resistance against Oomycota
WO2011085070A2 (en) * 2010-01-06 2011-07-14 Virginia Tech Intellectual Properties, Inc. Methods and compositions to improve the health of plants, animals and microbes by manipulating protein entry into symbionts and their hosts
AU2011237873B2 (en) 2010-04-06 2015-01-29 Biotalys NV Specific delivery of agrochemicals
JP5616449B2 (ja) 2010-07-20 2014-10-29 国立大学法人 東京大学 ナノ抗体を発現するトランスジェニックイネ
WO2012025602A1 (en) 2010-08-26 2012-03-01 Vib Vzw Insect binding antibodies
HUE036251T2 (hu) 2010-08-26 2018-06-28 Agrosavfe N V Kitinféle poliszacharid antigént kötõ fehérjék
US8907074B2 (en) * 2010-10-08 2014-12-09 Korea Research Institute Of Bioscience And Biotechnology Laticiferous tissue-specific SRPP promoter from Hevea brasiliensis and uses thereof
EP2763529A1 (en) 2011-10-06 2014-08-13 Agrosavfe N.V. Manufacturing of specifically targeting microcapsules
US20160145325A1 (en) * 2013-04-29 2016-05-26 Agrosavfe N.V. Agrochemical compositions comprising antibodies binding to sphingolipids
US20180222966A1 (en) * 2013-04-29 2018-08-09 Agrosavfe N.V. Transgenic plant comprising a polynucleotide encoding a variable domain of heavy-chain antibody
CA2966548A1 (en) 2014-11-05 2016-05-12 Agrosavfe Nv Transgenic plant comprising a polynucleotide encoding a variable domain of heavy-chain antibody

Also Published As

Publication number Publication date
JP2017536134A (ja) 2017-12-07
JP2021061843A (ja) 2021-04-22
WO2016071438A3 (en) 2016-06-23
US20180179551A1 (en) 2018-06-28
CA2966548A1 (en) 2016-05-12
US10858666B2 (en) 2020-12-08
US20210340556A1 (en) 2021-11-04
EP3215624C0 (en) 2023-11-29
WO2016071438A2 (en) 2016-05-12
EP3215624B1 (en) 2023-11-29
JP7089877B2 (ja) 2022-06-23
BR112017009330A2 (pt) 2017-12-19
EP3215624A2 (en) 2017-09-13

Similar Documents

Publication Publication Date Title
AR102550A1 (es) Planta transgénica que comprende un polinucleótido que codifica un dominio variable de anticuerpo de cadena pesada
EA201890945A1 (ru) Биологические препараты и их применение в отношении растений
CO2017006857A2 (es) Uso de compuestos de picolinamida como fungicidas
CO2019000099A2 (es) Composiciones que comprenden cepas bacterianas
CL2018001216A1 (es) Oxadiazoles sustituidos para combatir hongos fitopatógenos
BR112017014230A2 (pt) endófitos de semente através de cultivares e espécies, composições associadas e métodos de uso dos mesmos
CL2017001564A1 (es) Métodos para conferir o mejorar la resistencia a los herbicidas en las plantas y/o algas con variantes de oxidasa del protoporfirinógeno.
AR096496A1 (es) Composiciones y métodos para mejorar la germinación
EA201790177A1 (ru) Агротехнические способы
ECSP17037217A (es) Modificación de lípidos de plantas con contenido de pufas
ES2602992R1 (es) Composiciones y métodos para mejorar la producción de fruta
AR095298A1 (es) Plantas resistentes a hongos, que expresan hcp6
CR20170425A (es) Nuevas proteínas específicas para pioverdina y pioquelina
EP4144819C0 (en) MULCH COMPOSITION BASED ON BARK AND WOOD FIBERS
PE20181850A1 (es) Composiciones basadas en chlorelia seca y metodos para el mejoramiento de las plantas
BR112017014669A2 (pt) método para melhorar a precocidade no algodão
CO2017000558A2 (es) Variantes de proteínas de unión al factor h
AR093760A1 (es) Plantas resistentes a hongos, que expresan rlk2
UY36846A (es) Uso de anexina para mejorar el rendimiento en condiciones de estrés en plantas
BR112018005863A2 (pt) endófitos de brachiaria e métodos relacionados
CL2016001122A1 (es) Métodos de modulación del tamaño de las semillas y de los órganos de plantas
MX2016009126A (es) Metodo para repeler roedores.
AR096230A1 (es) Composiciones y métodos para implementar una mezcla de semillas transgénicas de refugio
AR095138A1 (es) Composición y uso de la misma
CL2019003164A1 (es) Uso de un compuesto para la protección de plantas mediante cierre estomático y método de protección de plantas mediante cierre estomático que comprende aplicar a las plantas dicho compuesto.