DE60335610D1 - Neoplasma-spezifische antikörper und deren verwendungen - Google Patents
Neoplasma-spezifische antikörper und deren verwendungenInfo
- Publication number
- DE60335610D1 DE60335610D1 DE60335610T DE60335610T DE60335610D1 DE 60335610 D1 DE60335610 D1 DE 60335610D1 DE 60335610 T DE60335610 T DE 60335610T DE 60335610 T DE60335610 T DE 60335610T DE 60335610 D1 DE60335610 D1 DE 60335610D1
- Authority
- DE
- Germany
- Prior art keywords
- neoplasma
- specific antibodies
- neoplasms
- diagnosis
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2510/00—Detection of programmed cell death, i.e. apoptosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE60335610T DE60335610D1 (de) | 2002-03-09 | 2003-03-10 | Neoplasma-spezifische antikörper und deren verwendungen |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10210427A DE10210427A1 (de) | 2002-03-09 | 2002-03-09 | Humaner monoklonaler Antikörper |
DE60335610T DE60335610D1 (de) | 2002-03-09 | 2003-03-10 | Neoplasma-spezifische antikörper und deren verwendungen |
PCT/IB2003/001335 WO2003076472A2 (en) | 2002-03-09 | 2003-03-10 | Neoplasm specific antibodies and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60335610D1 true DE60335610D1 (de) | 2011-02-17 |
Family
ID=27797631
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE10210427A Withdrawn DE10210427A1 (de) | 2002-03-09 | 2002-03-09 | Humaner monoklonaler Antikörper |
DE60335610T Expired - Lifetime DE60335610D1 (de) | 2002-03-09 | 2003-03-10 | Neoplasma-spezifische antikörper und deren verwendungen |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE10210427A Withdrawn DE10210427A1 (de) | 2002-03-09 | 2002-03-09 | Humaner monoklonaler Antikörper |
Country Status (8)
Country | Link |
---|---|
US (2) | US20050208056A1 (de) |
EP (2) | EP2292666A3 (de) |
AT (1) | ATE494307T1 (de) |
AU (1) | AU2003214537B2 (de) |
CA (1) | CA2478116A1 (de) |
DE (2) | DE10210427A1 (de) |
ES (1) | ES2359052T3 (de) |
WO (1) | WO2003076472A2 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL160029A0 (en) | 2001-07-24 | 2004-06-20 | Receptor, the use thereof, and mouse antibodies | |
DE10210427A1 (de) | 2002-03-09 | 2003-10-09 | Hans Konrad Mueller-Hermelink | Humaner monoklonaler Antikörper |
EP2322559A3 (de) * | 2002-07-04 | 2011-08-03 | Patrys Limited | Neoplasma-spezifische Antikörper und deren Verwendungen |
DE10311248A1 (de) | 2003-03-14 | 2004-09-30 | Müller-Hermelink, Hans Konrad, Prof. Dr. | Humaner monoklonaler Antikörper |
WO2004097019A1 (ja) * | 2003-04-30 | 2004-11-11 | Japan Science And Technology Agency | ヒト抗ヒトインターロイキン-18抗体およびその断片、並びにそれらの利用方法 |
NZ577824A (en) * | 2003-11-12 | 2010-10-29 | Patrys Ltd | Methods of identifying neoplasm-specific antibodies and uses thereof |
EP1531162A1 (de) | 2003-11-14 | 2005-05-18 | Heinz Vollmers | Antikörper SAM-6, der spezifisch von Adenocarzinom ist, und dessen Verwendungen |
DE10353175A1 (de) | 2003-11-14 | 2005-06-16 | Müller-Hermelink, Hans Konrad, Prof. Dr. | Humaner monoklonaler Antikörper mit fettsenkender Wirkung |
WO2006089002A2 (en) * | 2005-02-15 | 2006-08-24 | Yale University | Method for high throughput screening for antibodies and proteins inducing apoptosis |
WO2009033013A1 (en) * | 2007-09-05 | 2009-03-12 | Nurit Rachamim | Antibodies against flagellin and uses thereof |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4444744A (en) | 1980-03-03 | 1984-04-24 | Goldenberg Milton David | Tumor localization and therapy with labeled antibodies to cell surface antigens |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US5374548A (en) * | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
GB8705477D0 (en) | 1987-03-09 | 1987-04-15 | Carlton Med Prod | Drug delivery systems |
DE3722647A1 (de) | 1987-07-09 | 1989-01-19 | Gerhard Ohlenschlaeger | Galenische verwendung eines tripeptids als arzneimittel |
DE4107154A1 (de) * | 1990-10-11 | 1992-04-16 | Boehringer Mannheim Gmbh | Monoklonale antikoerper gegen melanom |
US5367060A (en) | 1991-05-24 | 1994-11-22 | Genentech, Inc. | Structure, production and use of heregulin |
IL101943A0 (en) | 1991-05-24 | 1992-12-30 | Genentech Inc | Structure,production and use of heregulin |
GB9324807D0 (en) | 1993-12-03 | 1994-01-19 | Cancer Res Campaign Tech | Tumour antibody |
US5639863A (en) * | 1994-06-21 | 1997-06-17 | Dan; Michael D. | Human monoclonal antibodies specific to cell cycle independent glioma surface antigen |
GB9601081D0 (en) * | 1995-10-06 | 1996-03-20 | Cambridge Antibody Tech | Specific binding members for human transforming growth factor beta;materials and methods |
AU4982097A (en) * | 1996-10-18 | 1998-05-15 | Board Of Regents, The University Of Texas System | Anti-erbb2 antibodies |
GB9822115D0 (en) * | 1998-10-09 | 1998-12-02 | King S College London | Treatment of inflammatory disease |
US7049132B1 (en) * | 1999-06-28 | 2006-05-23 | University Of Southern California | Stress-responsive induction of a therapeutic agent and methods of use |
US6677442B1 (en) * | 1999-10-29 | 2004-01-13 | University Of Kentucky Research Foundation | Nucleic acid encoding human REV1 protein |
MXPA02008144A (es) * | 2000-02-23 | 2002-11-29 | Amgen Inc | Agentes de enlace selectivos antagonistas de la proteina de enlace de osteoprotegerina. |
TWI318983B (en) * | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
DE10210427A1 (de) | 2002-03-09 | 2003-10-09 | Hans Konrad Mueller-Hermelink | Humaner monoklonaler Antikörper |
WO2005001052A2 (en) * | 2003-06-06 | 2005-01-06 | University Of Massachusetts | Modulation of apoptosis |
-
2002
- 2002-03-09 DE DE10210427A patent/DE10210427A1/de not_active Withdrawn
-
2003
- 2003-03-10 WO PCT/IB2003/001335 patent/WO2003076472A2/en not_active Application Discontinuation
- 2003-03-10 US US10/506,763 patent/US20050208056A1/en not_active Abandoned
- 2003-03-10 AT AT03710116T patent/ATE494307T1/de not_active IP Right Cessation
- 2003-03-10 AU AU2003214537A patent/AU2003214537B2/en not_active Ceased
- 2003-03-10 EP EP10182277A patent/EP2292666A3/de not_active Withdrawn
- 2003-03-10 DE DE60335610T patent/DE60335610D1/de not_active Expired - Lifetime
- 2003-03-10 CA CA002478116A patent/CA2478116A1/en not_active Abandoned
- 2003-03-10 EP EP03710116A patent/EP1485415B1/de not_active Expired - Lifetime
- 2003-03-10 ES ES03710116T patent/ES2359052T3/es not_active Expired - Lifetime
-
2010
- 2010-08-17 US US12/858,308 patent/US20110076763A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1485415B1 (de) | 2011-01-05 |
ATE494307T1 (de) | 2011-01-15 |
AU2003214537A1 (en) | 2003-09-22 |
EP2292666A2 (de) | 2011-03-09 |
DE10210427A1 (de) | 2003-10-09 |
WO2003076472A2 (en) | 2003-09-18 |
AU2003214537B2 (en) | 2010-02-18 |
EP1485415A2 (de) | 2004-12-15 |
US20050208056A1 (en) | 2005-09-22 |
CA2478116A1 (en) | 2003-09-18 |
US20110076763A1 (en) | 2011-03-31 |
ES2359052T3 (es) | 2011-05-18 |
EP2292666A3 (de) | 2011-06-08 |
WO2003076472A3 (en) | 2004-03-25 |
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