CA1042792A - Fluorescence quenching with immunological pairs in immunoassays - Google Patents

Fluorescence quenching with immunological pairs in immunoassays

Info

Publication number
CA1042792A
CA1042792A CA233,197A CA233197A CA1042792A CA 1042792 A CA1042792 A CA 1042792A CA 233197 A CA233197 A CA 233197A CA 1042792 A CA1042792 A CA 1042792A
Authority
CA
Canada
Prior art keywords
ligand
receptor
assay solution
amount
fluorescer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA233,197A
Other languages
English (en)
French (fr)
Inventor
Edwin F. Ullman
Moshe Schwarzberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syva Co
Original Assignee
Syva Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syva Co filed Critical Syva Co
Application granted granted Critical
Publication of CA1042792A publication Critical patent/CA1042792A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/18—Water
    • G01N33/1826—Organic contamination in water
    • G01N33/1833—Oil in water
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/816—Alkaloids, amphetamines, and barbiturates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
CA233,197A 1974-08-12 1975-08-11 Fluorescence quenching with immunological pairs in immunoassays Expired CA1042792A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49716774A 1974-08-12 1974-08-12
US05/591,386 US3996345A (en) 1974-08-12 1975-06-30 Fluorescence quenching with immunological pairs in immunoassays

Publications (1)

Publication Number Publication Date
CA1042792A true CA1042792A (en) 1978-11-21

Family

ID=27052409

Family Applications (1)

Application Number Title Priority Date Filing Date
CA233,197A Expired CA1042792A (en) 1974-08-12 1975-08-11 Fluorescence quenching with immunological pairs in immunoassays

Country Status (13)

Country Link
US (1) US3996345A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS6018940B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU501140B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR7505107A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1042792A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH621873A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2535574C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES440173A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2282115A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (2) GB1526242A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL47835A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL185423C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (2) SE427504B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (1829)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630328B2 (en) 1909-07-15 2003-10-07 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms
US4199559A (en) * 1974-08-12 1980-04-22 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4174384A (en) * 1975-06-30 1979-11-13 Syva Company Fluorescence quenching with immunological pairs in immunoassays
GB1573212A (en) * 1976-04-15 1980-08-20 Technicon Instr Immunoassay for gentamicin
US4160818A (en) * 1976-04-15 1979-07-10 Technicon Instruments Corporation Fluorimetric immunoassay for diphenylhydantoin
JPS5836308B2 (ja) * 1977-02-10 1983-08-08 大塚製薬株式会社 抗体の製造方法
IT1079045B (it) * 1977-05-16 1985-05-08 Syva Co Analisi imuunologica fluorescente a doppio ricettore
FR2394085A1 (fr) * 1977-06-10 1979-01-05 Syva Co Methode qualitative et quantitative de dosage fluorimetrique de composes organiques doues d'activite physiologique
US4208479A (en) * 1977-07-14 1980-06-17 Syva Company Label modified immunoassays
US4160645A (en) * 1977-07-14 1979-07-10 Syva Company Catalyst mediated competitive protein binding assay
USRE34394E (en) * 1978-01-23 1993-09-28 Baxter Diagnostics Inc. Method and composition for double receptor, specific binding assays
US4215102A (en) * 1979-01-05 1980-07-29 Lee Sin H Cytochemical agents and methods for the detection of steroid hormone receptors in human tissues
US4331590A (en) * 1978-03-13 1982-05-25 Miles Laboratories, Inc. β-Galactosyl-umbelliferone-labeled protein and polypeptide conjugates
US4220450A (en) * 1978-04-05 1980-09-02 Syva Company Chemically induced fluorescence immunoassay
US4235869A (en) * 1978-05-16 1980-11-25 Syva Company Assay employing a labeled Fab-fragment ligand complex
US4193983A (en) * 1978-05-16 1980-03-18 Syva Company Labeled liposome particle compositions and immunoassays therewith
US4318707A (en) * 1978-11-24 1982-03-09 Syva Company Macromolecular fluorescent quencher particle in specific receptor assays
US4238195A (en) * 1979-01-18 1980-12-09 Miles Laboratories, Inc. Fluorescer-labeled specific binding assays
CA1121345A (en) * 1979-03-05 1982-04-06 Robert A. Yoshida Method for competitive protein binding assays inhibiting non-specific interference
US4256834A (en) * 1979-04-09 1981-03-17 Syva Company Fluorescent scavenger particle immunoassay
US4284412A (en) * 1979-07-13 1981-08-18 Ortho Diagnostics, Inc. Method and apparatus for automated identification and enumeration of specified blood cell subclasses
US4287300A (en) * 1979-07-26 1981-09-01 Syva Company Charge effects in enzyme immunoassays
US4351760A (en) * 1979-09-07 1982-09-28 Syva Company Novel alkyl substituted fluorescent compounds and polyamino acid conjugates
NL8000173A (nl) * 1980-01-11 1981-08-03 Akzo Nv Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen.
US4329461A (en) * 1980-01-11 1982-05-11 Syva Company Fluorescent thyroid hormone conjugates and their uses
US4401764A (en) * 1980-02-07 1983-08-30 Technicon Instruments Corporation Immunoassays employing labeled reagent and a conjugate having two binding sites
US4318981A (en) * 1980-04-24 1982-03-09 Miles Laboratories, Inc. Homogeneous specific binding assay employing an intramolecularly modulated photogenic enzyme substrate label
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
EP0050684B1 (en) * 1980-10-27 1986-01-22 Syva Company Novel ether substituted fluorescein compounds as fluorescers and quenchers
JPS5782387A (en) * 1980-10-29 1982-05-22 Syva Co Novel ether substituted fluorescein compound
US4385126A (en) * 1980-11-19 1983-05-24 International Diagnostic Technology, Inc. Double tagged immunoassay
US4378458A (en) * 1981-03-30 1983-03-29 Baker Instruments Corporation Novel chromogenic and/or fluorogenic substrates for monitoring catalytic or enzymatic activity
US4378428A (en) * 1981-03-30 1983-03-29 Baker Instruments Corporation Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays
US4785080A (en) * 1981-03-30 1988-11-15 Baker Instruments Corporation Labeled analytes
US4442218A (en) * 1981-05-27 1984-04-10 Corning Glass Works Method of measuring degree of partitioning
JPS585659A (ja) * 1981-06-24 1983-01-13 ハイブリテツク　インコ−ポレ−テツド 単クロ−ン性抗体を使用する免疫学的、抑制試験
US4434150A (en) 1981-10-19 1984-02-28 Ortho Diagnostic Systems, Inc. Immunological reagents employing polymeric backbone possessing reactive functional groups
AU9094982A (en) * 1982-02-01 1983-08-11 Miles Laboratories Inc. Photogenic labels to alleviate quenching in immuno assays
US4472301A (en) * 1982-05-27 1984-09-18 Miles Laboratories, Inc. Propranolol immunogen and antibodies
US4687732A (en) * 1983-06-10 1987-08-18 Yale University Visualization polymers and their application to diagnostic medicine
US4719176A (en) * 1983-10-31 1988-01-12 Klotz Irving M Enzyme-free diagnostic binding reagents
US4865997A (en) * 1984-02-23 1989-09-12 Becton Dickinson And Company Assay for ligands by separating bound and free tracer from sample
US4708929A (en) * 1984-10-29 1987-11-24 Microgenics Corporation Methods for protein binding enzyme complementation assays
US4645828A (en) 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
US4791068A (en) * 1984-06-22 1988-12-13 Scripps Clinic And Research Foundation Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators
US4666862A (en) * 1984-08-14 1987-05-19 Ortho Diagnostic Systems Inc. Fluorescent energy transfer with phycobiliproteins
US5310687A (en) * 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US5221605A (en) * 1984-10-31 1993-06-22 Igen, Inc. Luminescent metal chelate labels and means for detection
US4743561A (en) * 1985-03-05 1988-05-10 Abbott Laboratories Luminescent assay with a reagent to alter transmitive properties of assay solution
IE64785B1 (en) 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
JPH0672883B2 (ja) * 1985-06-19 1994-09-14 コニカ株式会社 分析素子
US5279943A (en) * 1985-08-02 1994-01-18 Compagnie Oris Industrie Homogeneous process for the detection and/or determination by luminescence of an analyte in a medium in which it may be present
FR2585836B1 (fr) * 1985-08-02 1987-11-27 Commissariat Energie Atomique Procede homogene de detection et/ou de determination par luminescence d'un analyte dans un milieu susceptible de le contenir
US4689397A (en) * 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4777128A (en) * 1986-05-27 1988-10-11 Ethigen Corporation Fluorescence immunoassay involving energy transfer between two fluorophores
FR2617974B1 (fr) * 1987-07-07 1992-11-13 Stabiligen Procede de dosage immunologique par bio- ou chimio- luminescence
US5384241A (en) * 1987-09-11 1995-01-24 Enzo Diagnostics, Inc. Specific binding assay compound with inhibitive self-quenching characteristics
US5039607A (en) * 1988-05-17 1991-08-13 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5334513A (en) * 1988-05-17 1994-08-02 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5053054A (en) * 1988-09-12 1991-10-01 Ortho Pharmaceutical Corporation Methods and reagents for staining intracellular components
US5135863A (en) * 1988-12-23 1992-08-04 Syntex (U.S.A.) Inc. Compositions and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine
US5132432A (en) * 1989-09-22 1992-07-21 Molecular Probes, Inc. Chemically reactive pyrenyloxy sulfonic acid dyes
WO1991005063A1 (en) * 1989-10-05 1991-04-18 Exoxemis, Inc. Haloperoxidase acid optimum chemiluminescence assay system
US5108899A (en) * 1989-10-31 1992-04-28 Exoxemis, Inc. Chemiluminescence assay of in vivo inflammation
US5532138A (en) * 1990-04-26 1996-07-02 Behringwerke Ag Method and kits for determining peroxidatively active catalysts
US5614504A (en) * 1990-08-01 1997-03-25 The University Of South Florida Method of making inosine monophosphate derivatives and immunopotentiating uses thereof
US5578498A (en) * 1991-05-22 1996-11-26 Behringwerke Ag Metal chelate containing compositions for use in chemiluminescent assays
US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5340716A (en) * 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
US5279937A (en) * 1992-04-30 1994-01-18 Detechnology Canada Use of macroglobulins to improve the signal-to-background ratio in affinity binding assays
DE69316757T2 (de) * 1992-07-31 1998-05-07 Behringwerke AG, 35041 Marburg Photoaktivierbare chemiluminizierende matrices
US5874423A (en) * 1992-09-10 1999-02-23 Yissum Research Development Co. Of The Hebrew University Of Jerusalem Digitalis-like compounds
US6033898A (en) * 1992-12-30 2000-03-07 Abbott Laboratories Enhanced yeast expression using regulatory control sequences from yeast sorbitol dehydrogenase gene
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US6953573B1 (en) 1993-03-17 2005-10-11 University Of Washington Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
AU679008B2 (en) * 1993-05-06 1997-06-19 Chiron Diagnostics Corporation Mixed luminescent conjugate test assays
US6562333B1 (en) 1993-06-14 2003-05-13 Schering Corporation Purified mammalian CTLA-8 antigens and related reagents
US6103237A (en) * 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
US5516639A (en) * 1993-07-22 1996-05-14 Mayo Foundation For Medical Education And Research Antibodies specific for human prostate glandular kallkrein
US20040259113A1 (en) * 1993-07-22 2004-12-23 Mayo Foundation For Medical Education And Research, Hybritech Incorporated Method for detection of metastatic prostate cancer
US5684144A (en) * 1993-07-28 1997-11-04 University Of North Texas Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof
US6238931B1 (en) * 1993-09-24 2001-05-29 Biosite Diagnostics, Inc. Fluorescence energy transfer in particles
US7083984B2 (en) 1993-09-24 2006-08-01 Biosite, Inc. Hybrid phthalocyanine derivatives and their uses
US7322927B2 (en) 1993-09-24 2008-01-29 Biosite, Inc. Hybrid phthalocyanine derivatives and their uses
US6251687B1 (en) 1993-09-24 2001-06-26 Biosite Diagnostics, Inc. Fluorescence energy transfer and intramolecular energy transfer in particles using novel compounds
US5824799A (en) * 1993-09-24 1998-10-20 Biosite Diagnostics Incorporated Hybrid phthalocyanine derivatives and their uses
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6406855B1 (en) 1994-02-17 2002-06-18 Maxygen, Inc. Methods and compositions for polypeptide engineering
AU699748B2 (en) * 1994-05-10 1998-12-10 Hybritech Incorporated Recombinant HK2 polypeptide
AU2635295A (en) * 1994-06-13 1996-01-05 Henry Ford Health System A novel neuronal-neonatal gene: neuronatin
ATE201445T1 (de) 1994-08-12 2001-06-15 Myriad Genetics Inc Mutationen des mit 17q verbundenen ovarial- und brustkrebs empfindlichkeitsgens
ES2154712T5 (es) 1994-08-12 2009-12-14 The University Of Utah Research Foundation Metodo para diagnosticar la predisposicion al cancer de mama y de ovarios.
US8236493B2 (en) 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6974666B1 (en) * 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6531277B2 (en) 1994-10-25 2003-03-11 The Curators Of The University Of Missouri Endometriosis-specific secretory protein
US5843673A (en) * 1994-10-25 1998-12-01 Curators Of The University Of Missouri Method of screening for endometriosis
US20030152909A1 (en) * 1994-11-16 2003-08-14 Mitrani Eduardo N. In vitro micro-organs, and uses related thereto
US5633149A (en) 1994-12-07 1997-05-27 Incyte Pharmaceuticals, Inc. Polynucleotide encoding novel chemokine expressed in inflamed adenoid
US6692920B1 (en) * 1994-12-07 2004-02-17 Incyte Corporation Antibodies to a chemokine expressed in inflamed adenoid
PT800578E (pt) * 1994-12-28 2003-09-30 Univ Kentucky Sequencias do anticorpo 3h1 anti-idiotipico monoclonal recombinante associado ao antigenio carcioembrionario humano
US6949244B1 (en) * 1995-12-20 2005-09-27 The Board Of Trustees Of The University Of Kentucky Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof
EP1522845A1 (en) * 1995-02-02 2005-04-13 Chugai Seiyaku Kabushiki Kaisha Method for assay of analyte by adjustment of chemiluminescence
US7005509B1 (en) 1995-02-17 2006-02-28 Incyte Corporation Chemokine PANEC-1 polynucleotides and compositions and methods related thereto
US5777093A (en) * 1995-05-16 1998-07-07 Ramot-University Authority For Applied Research & Industrial Development Ltd. cDNAs associated with ataxia-telangiectasia
US5728807A (en) * 1995-05-16 1998-03-17 Ramot-University Authority For Applied Research And Industrial Development, Ltd. Mutated proteins associated with ataxia-telangiectasia
US5858661A (en) * 1995-05-16 1999-01-12 Ramot-University Authority For Applied Research And Industrial Development Ataxia-telangiectasia gene and its genomic organization
GB0112226D0 (en) * 2001-05-18 2001-07-11 Danisco Method of improving dough and bread quality
WO1997000271A1 (en) 1995-06-14 1997-01-03 The Regents Of The University Of California Novel high affinity human antibodies to tumor antigens
US5741662A (en) * 1995-12-18 1998-04-21 Quidel Corporation Direct stain specific binding assays for microorganisms
US5837492A (en) 1995-12-18 1998-11-17 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
AU1461597A (en) 1995-12-18 1997-07-14 Endorecherche Inc. Chromosome 13-linked breast cancer susceptibility gene
US7291463B2 (en) * 1996-01-23 2007-11-06 Affymetrix, Inc. Nucleic acid labeling compounds
US6864059B2 (en) * 1996-01-23 2005-03-08 Affymetrix, Inc. Biotin containing C-glycoside nucleic acid labeling compounds
US20010018514A1 (en) * 1998-07-31 2001-08-30 Mcgall Glenn H. Nucleic acid labeling compounds
US7423143B2 (en) * 1996-01-23 2008-09-09 Affymetrix. Inc. Nucleic acid labeling compounds
US7468243B2 (en) * 2001-03-12 2008-12-23 Affymetrix, Inc. 2-aminopyrimidin-4-one nucleic acid labeling compounds
US6965020B2 (en) 1996-01-23 2005-11-15 Affymetrix, Inc. Nucleic acid labeling compounds
US20040210045A1 (en) * 1996-01-23 2004-10-21 Mcgall Glenn Nucleic acid labeling compounds
US7282327B2 (en) * 1996-01-23 2007-10-16 Affymetrix, Inc. Nucleic acid labeling compounds
EP0880598A4 (en) 1996-01-23 2005-02-23 Affymetrix Inc RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
AU2189397A (en) 1996-02-08 1997-08-28 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
EP1728875A3 (en) 1996-02-08 2007-05-09 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
US6924094B1 (en) 1996-02-08 2005-08-02 Affymetrix, Inc. Chip-based species identification and phenotypic characterization of microorganisms
DE69733650T2 (de) * 1996-03-01 2006-04-20 Beckman Coulter, Inc., Fullerton System zum simultanen Durchführen einer Vielzahl von Ligandenbindungs-Untersuchungen
US5882644A (en) * 1996-03-22 1999-03-16 Protein Design Labs, Inc. Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof
US6129917A (en) * 1996-03-22 2000-10-10 The University Of Georgia Research Foundation, Inc. Immunogenic compositions comprising porphyromonas gingivalis proteins and/or peptides and methods
US6942862B2 (en) * 1996-04-01 2005-09-13 University Of Washington Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins
US6162931A (en) 1996-04-12 2000-12-19 Molecular Probes, Inc. Fluorinated xanthene derivatives
WO1997044461A2 (en) * 1996-05-22 1997-11-27 Novopharm Biotech, Inc. Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
US6063908A (en) * 1996-07-02 2000-05-16 Roche Diagnostics Corporation Reagents for lysergic acid diethylamide immunoassay
US20050069923A1 (en) * 1996-07-08 2005-03-31 Mullis Kary Banks Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
WO1998001533A1 (en) 1996-07-08 1998-01-15 Burstein Laboratories, Inc. Cleavable signal element device and method
US6342349B1 (en) 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
US6331275B1 (en) 1996-07-08 2001-12-18 Burstein Technologies, Inc. Spatially addressable, cleavable reflective signal elements, assay device and method
US5866336A (en) * 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
DE69722917T2 (de) 1996-07-18 2004-05-06 Dade Behring Marburg Gmbh Reagenzien für tests für mycophenolsäure
EP0880704B1 (en) * 1996-07-18 2003-09-24 Dade Behring Marburg GmbH Reagents for assays for mycophenolic acid
US5853990A (en) * 1996-07-26 1998-12-29 Edward E. Winger Real time homogeneous nucleotide assay
AU4055697A (en) 1996-08-16 1998-03-06 Schering Corporation Mammalian cell surface antigens; related reagents
US20070299005A1 (en) * 1996-09-24 2007-12-27 Tanox, Inc. Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
DE69735375T3 (de) * 1996-09-24 2010-09-02 Tanox, Inc., Houston Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung
US6093809A (en) * 1996-10-01 2000-07-25 University Technology Corporation Telomerase
US6261836B1 (en) 1996-10-01 2001-07-17 Geron Corporation Telomerase
US6610839B1 (en) * 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
US6475789B1 (en) 1996-10-01 2002-11-05 University Technology Corporation Human telomerase catalytic subunit: diagnostic and therapeutic methods
US7585622B1 (en) 1996-10-01 2009-09-08 Geron Corporation Increasing the proliferative capacity of cells using telomerase reverse transcriptase
US6808880B2 (en) * 1996-10-01 2004-10-26 Geron Corporation Method for detecting polynucleotides encoding telomerase
EP1783139B8 (en) 1996-10-01 2009-09-23 Geron Corporation Human telomerase catalytic subunit
GB9907461D0 (en) 1999-03-31 1999-05-26 King S College London Neurite regeneration
US6479263B1 (en) 1996-11-14 2002-11-12 Baylor College Of Medicine Method for detection of micrometastatic prostate cancer
EP1803816A3 (en) 1996-12-13 2007-09-26 Schering Corporation Mammalian cell surface antigens; related reagents
US5840322A (en) * 1996-12-19 1998-11-24 Ramot-University Authority For Applied Research & Industrial Devel. Ltd. Anti-oral-microbial adhesion fraction derived from vaccinium
EP2172478A3 (en) 1997-02-07 2010-07-28 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Activity-dependent neurotrophic factor III (ADNF III)
CA2281205A1 (en) 1997-02-12 1998-08-13 Eugene Y. Chan Methods and products for analyzing polymers
US20050013825A1 (en) * 1997-04-18 2005-01-20 Geron Corporation Vaccine containing the catalytic subunit of telomerase for treating cancer
US7622549B2 (en) * 1997-04-18 2009-11-24 Geron Corporation Human telomerase reverse transcriptase polypeptides
US7413864B2 (en) * 1997-04-18 2008-08-19 Geron Corporation Treating cancer using a telomerase vaccine
US6103536A (en) 1997-05-02 2000-08-15 Silver Lake Research Corporation Internally referenced competitive assays
DE69836630T2 (de) 1997-05-07 2007-10-11 Schering Corp. Menschliche toll-ähnliche rezeptorproteine, zugehörige reagenzien und verfahren
US7115722B1 (en) 1997-05-22 2006-10-03 Viventia Biotech, Inc. Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
US7314711B2 (en) * 1997-05-23 2008-01-01 Bioveris Corporation Assays employing electrochemiluminescent labels and electrochemiluminescence quenchers
US20020098190A1 (en) * 1997-06-13 2002-07-25 Malaya Chatterjee Compositions and methods for treating tumors bearing HMFG and CEA antigens
WO1998059073A1 (en) 1997-06-20 1998-12-30 Mayo Foundation For Medical Education And Research Method for detection of breast cancer
US20020122807A1 (en) * 1998-07-07 2002-09-05 Dan Michael D. Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
PL337942A1 (en) 1997-07-09 2000-09-11 Schering Corp Isolated genes of dendricall cell membranic proteins
JP2001500391A (ja) * 1997-07-11 2001-01-16 ユニバーシティ オブ ノース テキサス Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ ｃｓｒＢ遺伝子、それによりコードされるＲＮＡ、および使用方法
US6723550B1 (en) * 1997-07-15 2004-04-20 Genencor International, Inc. Proteases from gram-positive organisms
US20030157642A1 (en) 1997-07-15 2003-08-21 Caldwell Robert M. Increasing production of proteins in gram-positive microorganisms
US6762039B2 (en) * 1997-07-15 2004-07-13 Genencor International, Inc. Bacillus subtillis with an inactivated cysteine protease-1
US6506579B1 (en) 1997-07-15 2003-01-14 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms using SecG
US6521421B1 (en) 1997-07-16 2003-02-18 Genencor International, Inc. Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same
CO4810232A1 (es) 1997-07-25 1999-06-30 Schering Corp Citoquinas de mamiferos y sus secuencias codificadoras
US6180411B1 (en) 1997-08-01 2001-01-30 The Regents Of The University Of California Light-triggered indicators that memorize analyte concentrations
PT1003861E (pt) 1997-08-01 2007-01-31 Schering Corp Proteínas de membrana de células de mamíferos;reagentes relacionados
US5929049A (en) 1997-08-08 1999-07-27 Dade Behring Marburg Gmbh Polysaccharide conjugates of biomolecules
US7973156B2 (en) * 1997-08-21 2011-07-05 Quark Pharmaceuticals Inc. Hypoxia-regulated genes
AU9110798A (en) * 1997-08-21 1999-03-08 Quark Biotech, Inc. Hypoxia-regulated genes
US20030104973A1 (en) * 1997-08-21 2003-06-05 Quark Biotech, Inc. Hypoxia-regulated genes
US7252950B1 (en) 1997-09-04 2007-08-07 The Regents Of The University Of California Assays for detecting modulators of cytoskeletal function
US7070921B2 (en) 2000-04-28 2006-07-04 Molecular Devices Corporation Molecular modification assays
US6300117B1 (en) * 1997-09-15 2001-10-09 Genencor International, Inc. Proteases from gram-positive organisms
US6521440B1 (en) 1997-09-15 2003-02-18 Genencor International, Inc. Proteases from gram-positive organisms
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US7632651B2 (en) 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
US7378244B2 (en) * 1997-10-01 2008-05-27 Geron Corporation Telomerase promoters sequences for screening telomerase modulators
US6103537A (en) * 1997-10-02 2000-08-15 Aclara Biosciences, Inc. Capillary assays involving separation of free and bound species
US6284496B1 (en) 1997-10-03 2001-09-04 University Of South Florida DNA vector for determining the presence of out-of-reading-frame mutations
DE19745001A1 (de) * 1997-10-11 1999-05-06 Evotec Biosystems Ag Verfahren zur Affinitätsmarkierung von Oligo- oder Polymeren
MXPA00003705A (es) 1997-10-17 2002-04-17 Univ South Florida Metodo para diagnosticar y monitorear deficiencias inmunes celulares.
US6607829B1 (en) 1997-11-13 2003-08-19 Massachusetts Institute Of Technology Tellurium-containing nanocrystalline materials
US6322901B1 (en) 1997-11-13 2001-11-27 Massachusetts Institute Of Technology Highly luminescent color-selective nano-crystalline materials
GB9724627D0 (en) 1997-11-20 1998-01-21 Genencor Int Bv Gram positive microorganism formate pathway
US6316241B1 (en) * 1997-11-20 2001-11-13 Genencor International, Inc. Alpha/beta hydrolase-fold enzymes
GB9724629D0 (en) * 1997-11-20 1998-01-21 Genencor Int Bv Alpha/beta hydrolase-fold enzymes
US6306642B1 (en) * 1997-11-24 2001-10-23 Quidel Corporation Enzyme substrate delivery and product registration in one step enzyme immunoassays
US6207392B1 (en) 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
US6699723B1 (en) 1997-11-25 2004-03-02 The Regents Of The University Of California Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
US5990479A (en) 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
DE19756782A1 (de) 1997-12-19 1999-06-24 Dade Behring Marburg Gmbh Nachweis und Bestimmung festphasenassoziierter Faktoren
DE19756773A1 (de) 1997-12-19 1999-06-24 Dade Behring Marburg Gmbh Neues Verfahren und Diagnosemittel zur Hämostase-Diagnostik
AU1944699A (en) * 1997-12-23 1999-07-12 Vicam, L.P. Generic signalling mechanism for detection of analytes
US6599731B1 (en) * 1997-12-30 2003-07-29 Genencor International, Inc. Proteases from gram positive organisms
US6465186B1 (en) 1997-12-30 2002-10-15 Genecor International, Inc. Proteases from gram positive organisms
US6528255B1 (en) * 1997-12-30 2003-03-04 Genencor International, Inc. Proteases from gram positive organisms
GB9727470D0 (en) 1997-12-30 1998-02-25 Genencor Int Bv Proteases from gram positive organisms
US7687057B2 (en) 1998-01-09 2010-03-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US6780609B1 (en) 1998-10-23 2004-08-24 Genome Therapeutics Corporation High bone mass gene of 1.1q13.3
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
US6673914B1 (en) 1998-01-22 2004-01-06 John Wayne Cancer Institute Human tumor-associated gene
WO2000018885A1 (en) 1998-09-29 2000-04-06 Gamida Cell Ltd. Methods of controlling proliferation and differentiation of stem and progenitor cells
US6596501B2 (en) 1998-02-23 2003-07-22 Fred Hutchinson Cancer Research Center Method of diagnosing autoimmune disease
WO1999045124A2 (en) 1998-03-04 1999-09-10 Genencor International, Inc. Modified forms of pullulanase
EP2295978A3 (en) 1998-03-20 2012-06-06 The Curators Of The University Of Missouri Early pregnancy diagnosis using PAGs(Pregnancy-associated Glycoproteins)
US8062908B2 (en) * 1999-03-29 2011-11-22 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US6303081B1 (en) 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
DK1086372T3 (da) * 1998-03-30 2006-09-18 Orasure Technologies Inc Opsamlingsindretning til enkelttrinsanalyse af mundvæsker
EP1095183B1 (en) * 1998-03-31 2012-02-22 Esoterix Genetic Laboratories, LLC Methods for the diagnosis and treatment of lung cancer
US6337200B1 (en) * 1998-03-31 2002-01-08 Geron Corporation Human telomerase catalytic subunit variants
US6949367B1 (en) 1998-04-03 2005-09-27 Epoch Pharmaceuticals, Inc. Modified oligonucleotides for mismatch discrimination
US6683173B2 (en) * 1998-04-03 2004-01-27 Epoch Biosciences, Inc. Tm leveling methods
US7045610B2 (en) * 1998-04-03 2006-05-16 Epoch Biosciences, Inc. Modified oligonucleotides for mismatch discrimination
US7108968B2 (en) * 1998-04-03 2006-09-19 Affymetrix, Inc. Mycobacterial rpoB sequences
US7715989B2 (en) * 1998-04-03 2010-05-11 Elitech Holding B.V. Systems and methods for predicting oligonucleotide melting temperature (TmS)
US7411068B2 (en) * 1998-04-08 2008-08-12 Terpetschnig Ewald A Luminescent compounds
US6538129B1 (en) 1999-04-07 2003-03-25 Ewald A. Terpetschnig Luminescent compounds
US20030235846A1 (en) * 1998-04-08 2003-12-25 Terpetschnig Ewald A. Luminescent compounds
AU3386399A (en) * 1998-04-08 1999-10-25 Ewald A. Terpetschnig Luminescent compounds
US7250517B2 (en) * 1998-04-08 2007-07-31 Ewald A. Terpetschnig Luminescent compounds
US6872537B1 (en) 1998-04-14 2005-03-29 Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
WO1999053295A1 (en) 1998-04-14 1999-10-21 The Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6699969B1 (en) 1998-04-14 2004-03-02 The Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US20080206206A1 (en) 1998-05-07 2008-08-28 University Of South Florida Bone marrow-derived neuronal cells
US6153442A (en) * 1998-05-20 2000-11-28 Dade Behring Inc. Reagents and methods for specific binding assays
US6303325B1 (en) 1998-05-29 2001-10-16 Dade Behring Inc. Method for detecting analytes
EP1086123A1 (en) * 1998-06-09 2001-03-28 Immco Diagnostics Solution-phase elisa
GB9814506D0 (en) * 1998-07-03 1998-09-02 Stanley Christopher J Optical sensor for insitu measurement of analytes
PT1542014E (pt) 1998-07-03 2007-01-31 Precisense As Sensor óptico biodegradável para fazer in situ medições das substâncias a analisar
USRE38525E1 (en) 1998-07-03 2004-06-08 Torsana Diabetes Diagnostics A/S Optical sensor for in situ measurement of analytes
US6344443B1 (en) 1998-07-08 2002-02-05 University Of South Florida Peptide antagonists of tumor necrosis factor alpha
AU4994899A (en) 1998-07-13 2000-02-01 University Of South Florida Modulation of the phospholipase a2 pathway as a therapeutic
EP1097378A2 (en) * 1998-07-21 2001-05-09 Burstein Laboratories Inc. Optical disc-based assay devices and methods
ATE231186T1 (de) 1998-07-21 2003-02-15 Danisco Lebensmittel
WO2000005579A1 (en) 1998-07-22 2000-02-03 Syntron Bioresearch, Inc. Multiple analyte assay device
US6187563B1 (en) 1998-08-07 2001-02-13 Yale University βIV-spectrin-polypeptides and nucleic acids encoding same
SE9803099D0 (sv) 1998-09-13 1998-09-13 Karolinska Innovations Ab Nucleic acid transfer
US6306610B1 (en) 1998-09-18 2001-10-23 Massachusetts Institute Of Technology Biological applications of quantum dots
US6251303B1 (en) 1998-09-18 2001-06-26 Massachusetts Institute Of Technology Water-soluble fluorescent nanocrystals
US6617583B1 (en) * 1998-09-18 2003-09-09 Massachusetts Institute Of Technology Inventory control
EP1897949B1 (en) 1998-09-21 2014-11-12 Merck Sharp & Dohme Corp. Human interleukin-B50. Therapeutic uses
EP1115888B1 (en) 1998-09-24 2008-03-12 Indiana University Research and Technology Corporation Water-soluble luminescent quantum dots and bioconjugates thereof
EP0997476A3 (en) 1998-09-25 2000-07-19 Schering-Plough Antibodies to a mammalian Langerhans cell antigen and their uses
US6153411A (en) 1998-10-30 2000-11-28 American Water Works Company, Inc. Methods and kits for detection of Cryptosporidium parvum using immunomagnetic separation and amplification
ATE531801T1 (de) 1999-01-11 2011-11-15 Schering Corp Interleukin-17-verwandte säugetier-cytokine, polynukleotide, die diese kodieren und deren verwndung
NZ513303A (en) * 1999-02-04 2003-03-28 Technion Res & Dev Foundation Three dimensional plug flow bioreactor, and its use for the maintenance and expansion of hemopoietic stem cells and/or progenitor cells
US6156515A (en) * 1999-02-09 2000-12-05 Urocor, Inc. Prostate-specific gene for diagnosis, prognosis and management of prostate cancer
ATE420894T1 (de) 1999-03-11 2009-01-15 Schering Corp Cytokine aus säugetieren, verwandte reagenzien und verfahren
WO2000063683A1 (en) 1999-04-20 2000-10-26 Target Discovery, Inc. Polypeptide fingerprinting methods, metabolic profiling, and bioinformatics database
EP2341143A1 (en) 1999-05-13 2011-07-06 Medical Research Council OX2 receptor homolog
AU5011200A (en) 1999-05-14 2000-12-05 Arbor Vita Corporation Molecular interactions in hematopoietic cells
US6440682B1 (en) * 1999-05-28 2002-08-27 Detroit R&D Inc. Detection of hypertension using immunoreactive metabolic products
US6787318B1 (en) * 1999-06-01 2004-09-07 Roskamp Research Institute, Llc Assay for evaluating the therapeutic effectiveness of agents in reducing Alzheimer's disease pathology
ATE424456T1 (de) 1999-06-01 2009-03-15 Schering Corp Säugetier-rezeptorproteine; ähnliche reagentien und methoden
US7534605B2 (en) * 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
GB9914210D0 (en) 1999-06-17 1999-08-18 Danisco Promoter
US6262265B1 (en) 1999-06-18 2001-07-17 Microgenics Corporation Non-hydrolyzable analogs of heroin metabolites suitable for use in immunoassay
CN1420933A (zh) * 1999-06-25 2003-05-28 耶路撒冷希伯来大学伊森姆研究发展公司 应用微器官诱导血管生成的方法
US20060127366A1 (en) * 1999-06-25 2006-06-15 Mitrani Eduardo N Method and device for inducing biological processes by micro-organs
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
WO2001002374A1 (en) 1999-07-06 2001-01-11 Surromed, Inc. Bridged fluorescent dyes, their preparation and their use in assays
ES2330406T3 (es) 1999-07-30 2009-12-10 Schering Corporation Citocinas de mamifero; reactivos relacionados.
US6875582B1 (en) 1999-08-19 2005-04-05 Omniscience Pharmaceuticals, Inc. Methods and targets of antibiotic resistance
US7101839B1 (en) 1999-08-30 2006-09-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
US7811981B2 (en) * 1999-08-30 2010-10-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
EP1905832A3 (en) 1999-09-09 2009-09-09 Schering Corporation Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions
US6998232B1 (en) 1999-09-27 2006-02-14 Quark Biotech, Inc. Methods of diagnosing bladder cancer
US7668658B2 (en) 1999-10-13 2010-02-23 Sequenom, Inc. Methods for generating databases and databases for identifying polymorphic genetic markers
US7030228B1 (en) 1999-11-15 2006-04-18 Miltenyi Biotec Gmbh Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
AU784258B2 (en) 1999-11-19 2006-03-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Aspegillus niger beta-glucosidase gene, protein and uses thereof
EP1232185A2 (en) 1999-11-24 2002-08-21 Schering Corporation Methods of inhibiting metastasis
EP2287185A3 (en) 1999-12-06 2012-10-10 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
US6544792B1 (en) 1999-12-21 2003-04-08 Genencor International, Inc. Production of secreted polypeptides
DE50014159D1 (de) 1999-12-22 2007-04-26 Dade Behring Marburg Gmbh Lösungen von humanem Procalcitonin
DE50015156D1 (de) 1999-12-22 2008-06-26 Dade Behring Marburg Gmbh Gegen Procalcitonin gerichtete Antikörper, ihre Herstellung und Verwendung
US6544506B2 (en) 2000-01-05 2003-04-08 Yeda Research & Development Co. Ltd. Veto cells effective in preventing graft rejection and devoid of graft versus host potential
US7230088B2 (en) * 2001-07-03 2007-06-12 Mallinckrodt, Inc. Compounds for dual photodiagnosis and therapy
WO2001053323A2 (en) * 2000-01-24 2001-07-26 Ramot University Authority For Applied Research & Industrial Development Ltd. Plants tolerant of environmental stress conditions, methods of generating same and novel polynucleotide sequence utilized thereby
DE10003734A1 (de) * 2000-01-28 2001-08-02 Bosch Gmbh Robert Detektionsverfahren und -vorrichtung
US6965010B2 (en) * 2000-02-25 2005-11-15 Licentia, Ltd. Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins
US20040002068A1 (en) 2000-03-01 2004-01-01 Corixa Corporation Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
CA2401781A1 (en) 2000-03-01 2001-09-07 Epoch Biosciences, Inc. Modified oligonucleotides for mismatch discrimination
EP1944310A3 (en) 2000-03-01 2008-08-06 Epoch Biosciences, Inc. Modified oligonucleotides for mismatch discrimination
DE60035127T2 (de) 2000-03-06 2008-02-14 Dade Behring Marburg Gmbh Mit polysacchariden beschichtete träger, deren herstellung und verwendung
US7875442B2 (en) * 2000-03-24 2011-01-25 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
US7829313B2 (en) * 2000-03-24 2010-11-09 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
WO2006053769A1 (en) 2004-11-18 2006-05-26 Eppendorf Array Technologies Real-time quantification of multiple targets on a micro-array
US8288128B2 (en) * 2004-11-18 2012-10-16 Eppendorf Array Technologies S.A. Real-time quantification of multiple targets on a micro-array
IL151860A0 (en) 2000-03-27 2003-04-10 Technion Res & Dev Foundation Single chain class i major histocompatibility complexes, constructs encoding same and methods of generating same
US20030108927A1 (en) * 2000-04-03 2003-06-12 Kathryn Leishman Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases
US6676939B2 (en) 2000-04-18 2004-01-13 Schering Corporation Methods of modulating IL-174 response
IL135884A (en) * 2000-04-30 2005-08-31 Yissum Res Dev Co Method for measuring non-transferrin bound iron
WO2001084157A2 (en) 2000-05-04 2001-11-08 Dade Behring Marburg Gmbh Compositions for detection of multiple analytes
US7019129B1 (en) 2000-05-09 2006-03-28 Biosearch Technologies, Inc. Dark quenchers for donor-acceptor energy transfer
US7422743B2 (en) 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
MXPA02011081A (es) 2000-05-10 2003-03-10 Schering Corp Proteinas de subunidad de receptor de citocina de mamifero, reactivos y metodos relacionados.
EP1908837A3 (en) 2000-05-25 2008-06-11 Schering Corporation Human receptor proteins, related reagents and methods
WO2005000087A2 (en) * 2003-06-03 2005-01-06 Chiron Corporation Gene products differentially expressed in cancerous colon cells and their methods of use ii
US6936702B2 (en) 2000-06-07 2005-08-30 Li-Cor, Inc. Charge-switch nucleotides
EP2226330B1 (en) 2000-06-07 2013-09-18 Pacific Biosciences of California, Inc. Charge-switch nucleotides
US7846733B2 (en) 2000-06-26 2010-12-07 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
GB0016841D0 (en) 2000-07-07 2000-08-30 Stanley Christopher J Optical device for measurement of analytes in tears
US6958214B2 (en) 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
HUP0300810A2 (hu) 2000-07-20 2003-08-28 M.G.V.S. Ltd. Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazása
US20040037828A1 (en) 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
ES2387329T3 (es) 2000-08-08 2012-09-20 Technion Research And Development Foundation Ltd. Composiciones farmacéuticas y procedimientos útiles para modular la angiogénesis
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
EP1683874A3 (en) 2000-08-29 2006-10-11 YEDA RESEARCH AND DEVELOPMENT Co. LTD. Methods of isolating genes encoding proteins of specific function and of screening for pharmaceutically active agents
CA2419979A1 (en) 2000-09-08 2002-03-14 Schering Corporation Mammalian genes; related reagents and methods
EP1315830A4 (en) 2000-09-08 2005-10-19 Univ Texas COMPOSITIONS AND METHODS RELATING TO TARGETING PEPTIDES IN IN VIVO
US6673623B1 (en) 2000-09-12 2004-01-06 Novocure, Inc. Methods and compositions that control lipid production
ATE312932T1 (de) 2000-09-18 2005-12-15 Genencor Int Zwillingsarginin translokation in bacillus
US20070281037A9 (en) * 2000-09-28 2007-12-06 Nanocyte Inc. Sterile preparations and compositions including stinging capsules and methods of producing and using same
US7632522B2 (en) * 2000-09-28 2009-12-15 Nanocyte Inc. Use of stinging cells/capsules for the delivery of active agents to keratinous substances
AU2001295850A1 (en) * 2000-09-28 2002-04-08 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue
US6815164B2 (en) 2000-10-06 2004-11-09 Nugen Technologies, Inc. Methods and probes for detection and/or quantification of nucleic acid sequences
GB0025147D0 (en) 2000-10-13 2000-11-29 Torsana Diabetes Diagnostics A Optical sensor for in situ measurement of analytes
US7045283B2 (en) 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
WO2002061661A2 (en) 2000-10-19 2002-08-08 Target Discovery, Inc. Methods for determining protein and peptide terminal sequences
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
WO2003033514A1 (en) 2001-10-19 2003-04-24 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
AU2400202A (en) 2000-11-17 2002-05-27 Vascular Biogenics Ltd Promoters exhibiting endothelial cell specificity and methods of using same
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
JP4162486B2 (ja) 2000-11-24 2008-10-08 ヴァスキュラー バイオジェニックス リミテッド アテローム性動脈硬化を防止および処置するための規定された酸化型リン脂質を用いる方法およびそのような酸化型リン脂質を含有する組成物
JP2004514445A (ja) * 2000-11-29 2004-05-20 リンクス　バイオテック　ジーエムビーエイチ 新規な網膜特異的ヒトタンパク質Ｃ７ｏｒｆ９、Ｃ１２ｏｒｆ７、ＭＰＰ４およびＦ３７９
EP1337152A4 (en) * 2000-11-30 2004-08-11 Yeda Res & Dev METHODS OF USING CULTURED T CELLS THAT DO NOT INDUCE HOST Graft Reaction (GVHD) TO TREAT DISEASE
KR20030067696A (ko) 2000-11-30 2003-08-14 모렉큐랄 스킨케어 리미티드 질병의 진단 및 치료
NO20006130D0 (no) * 2000-12-01 2000-12-01 Erling Sundrehagen Reagens og analysemetode
EP1354064A2 (en) 2000-12-01 2003-10-22 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
AU2002220275A1 (en) * 2000-12-08 2002-06-18 The Board Of Trustees Of The University Of Illinois Mutated class ii major histocompatibility proteins
EP1427847B1 (en) 2000-12-13 2010-07-28 Nugen Technologies, Inc. Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
DE10064827A1 (de) * 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
WO2002057408A2 (en) * 2001-01-17 2002-07-25 Ramot At Tel Aviv University Ltd. Chitinases, derived from carnivorous plants polynucleotide sequences encoding thereof, and methods of isolating and using same
GB0101762D0 (en) * 2001-01-23 2001-03-07 Medical Res Council Method
US20050202098A1 (en) 2001-01-31 2005-09-15 Tolaren Disease therapy using dying or dead cells
CA2475021A1 (en) * 2001-01-31 2002-08-08 Dror Mevorach Induction of tolerance by apoptotic and/or necrotic cells
BR0205268A (pt) 2001-03-09 2004-11-30 Nugen Technologies Inc Processos e composições para a mplificação de sequências de rna
WO2002072892A1 (en) 2001-03-12 2002-09-19 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences by asynchronous base extension
US20030104410A1 (en) * 2001-03-16 2003-06-05 Affymetrix, Inc. Human microarray
US20030003454A1 (en) 2001-03-23 2003-01-02 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Methods and kits for determining a risk to develop cancer, for evaluating an effectiveness and dosage of cancer therapy and for correlating between an activity of a DNA repair enzyme and a cancer
US20030220475A1 (en) * 2001-04-03 2003-11-27 Fields Howard A. Neutralizing immunogenic hev polypepetides
AU2002254524A1 (en) * 2001-04-06 2002-10-21 The Government Of The United States Of America, Represented By The Secretary, Department Of Health A Use of semenogelin in the diagnosis, prognosis and treatment of cancer
BR0209154A (pt) 2001-05-18 2004-07-20 Danisco Processo de preparação de uma massa com uma enzima
US7132401B2 (en) 2001-05-22 2006-11-07 Merck & Co., Inc. Beta-secretase substrates and uses thereof
US7118907B2 (en) * 2001-06-06 2006-10-10 Li-Cor, Inc. Single molecule detection systems and methods
US6770622B2 (en) 2001-06-08 2004-08-03 Gary A. Jarvis N-terminally truncated galectin-3 for use in treating cancer
US20070190534A1 (en) * 2001-06-11 2007-08-16 Genesis Genomics Inc. Mitochondrial sites and genes associated with prostate cancer
US20030003510A1 (en) * 2001-06-27 2003-01-02 Bray Terry L. Biophotonic sensors and methods of use thereof
WO2003003015A2 (en) * 2001-06-28 2003-01-09 Advanced Research And Technology Institute, Inc. Methods of preparing multicolor quantum dot tagged beads and conjugates thereof
GB0116853D0 (en) 2001-07-10 2001-09-05 Torsana Diabetes Diagnostics A Optical sensor containing particles for in SITU measurement of analytes
EP1414838A4 (en) * 2001-07-19 2005-12-14 Yissum Res Dev Co POLYPEPTIDES HAVING CATALYTIC ACTIVITY OF CAROTENOID ISOMERASE, NUCLEIC ACIDS ENCODING THESE POLYPEPTIDES AND APPLICATIONS THEREOF
US20030031627A1 (en) * 2001-07-31 2003-02-13 Mallinckrodt Inc. Internal image antibodies for optical imaging and therapy
US6833441B2 (en) * 2001-08-01 2004-12-21 Abmaxis, Inc. Compositions and methods for generating chimeric heteromultimers
DE60237696D1 (de) * 2001-08-01 2010-10-28 Univ Utah Am n-terminus trunkierte isoformen von zyklischen phosphodiesterasen pde3a
US20030082596A1 (en) * 2001-08-08 2003-05-01 Michael Mittmann Methods of genetic analysis of probes: test3
US20060073530A1 (en) * 2001-08-15 2006-04-06 Olaf Schneewind Methods and compositions involving sortase B
WO2003017817A2 (en) 2001-08-16 2003-03-06 Bar Ilan University Diagnosis, prevention and treatment of cancer
US20040136972A1 (en) 2001-09-07 2004-07-15 Yeda Research And Development Co. Ltd. Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
WO2003024993A2 (en) 2001-09-20 2003-03-27 Board Of Regents, The University Of Texas System Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using elisa assays
AU2002330102A1 (en) * 2001-09-28 2003-04-14 Aspenbio, Inc. Bovine pregnancy test
GB0212544D0 (en) * 2002-05-30 2002-07-10 Microsens Biophage Ltd Methods for detection of target molecules and molecular interactions
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US7138370B2 (en) 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
US8323903B2 (en) * 2001-10-12 2012-12-04 Life Technologies Corporation Antibody complexes and methods for immunolabeling
US20050069962A1 (en) 2001-10-12 2005-03-31 Archer Robert M Antibody complexes and methods for immunolabeling
EP2316485A1 (en) 2001-10-12 2011-05-04 Schering Corporation Use of bispecific antibodies to regulate immune responses
US7045319B2 (en) * 2001-10-30 2006-05-16 Ribomed Biotechnologies, Inc. Molecular detection systems utilizing reiterative oligonucleotide synthesis
US20040054162A1 (en) * 2001-10-30 2004-03-18 Hanna Michelle M. Molecular detection systems utilizing reiterative oligonucleotide synthesis
US7175983B2 (en) * 2001-11-02 2007-02-13 Abmaxis, Inc. Adapter-directed display systems
DE10153829A1 (de) * 2001-11-05 2003-05-28 Bayer Ag Assay basierend auf dotierten Nanoteilchen
WO2003042697A1 (en) * 2001-11-14 2003-05-22 Genospectra, Inc. Biochemical analysis system with combinatorial chemistry applications
WO2003043524A2 (en) 2001-11-20 2003-05-30 The Curators Of The University Of Missouri Compositions and methods for accurate early pregnancy diagnosis
US6952704B2 (en) * 2001-11-26 2005-10-04 Microsoft Corporation Extending a directory schema independent of schema modification
US9575070B2 (en) * 2001-12-04 2017-02-21 Wayne State University Neoepitope detection of disease using protein arrays
WO2003048298A2 (en) * 2001-12-05 2003-06-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nanoparticles containing polymeric nucleic acid homologs, pharmaceutical compositions and articles of manufacture containing same and methods of use thereof
US20050085432A1 (en) * 2001-12-26 2005-04-21 Aviva Lapidot Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections
IL152904A0 (en) 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
WO2003062404A1 (en) 2002-01-25 2003-07-31 Gamida-Cell Ltd. Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby
US20040052928A1 (en) 2002-09-06 2004-03-18 Ehud Gazit Peptides and methods using same for diagnosing and treating amyloid-associated diseases
US7781396B2 (en) * 2002-01-31 2010-08-24 Tel Aviv University Future Technology Development L.P. Peptides directed for diagnosis and treatment of amyloid-associated disease
US20070021345A1 (en) 2003-06-30 2007-01-25 Ehud Gazit Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases
MXPA04007426A (es) 2002-02-01 2004-10-11 Schering Corp Usos de citosina de mamifero; reactivos relacionados.
US6992176B2 (en) 2002-02-13 2006-01-31 Technion Research & Development Foundation Ltd. Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease
SI1487972T1 (sl) 2002-02-21 2016-03-31 Institute Of Virology Slovak Academy Of Sciences Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe
US7053188B2 (en) 2002-02-22 2006-05-30 Purdue Research Foundation Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase
EP1573035B1 (en) 2002-02-22 2015-09-02 The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services Brother of the regulator of imprinted sites (boris)
WO2003078567A2 (en) * 2002-03-18 2003-09-25 Gamida-Cell Ltd. Methods of inducing differentiation in ex vivo expanded stem cells
US7611723B2 (en) * 2002-03-26 2009-11-03 Nanocyte Inc. Stinging cells expressing an exogenous polynucleotide encoding a therapeutic, diagnostic or a cosmetic agent and methods compositions and devices utilizing such stinging cells or capsules derived therefrom for delivering the therapeutic, diagnostic or cosmetic agent into a tissue
DE10214019A1 (de) * 2002-03-30 2003-10-16 Detlef Mueller-Schulte Lumineszierende, sphärische, nicht autofluoreszierende Silicagel-Partikel mit veränderbaren Emissionsintensitäten und -frequenzen
US7332585B2 (en) 2002-04-05 2008-02-19 The Regents Of The California University Bispecific single chain Fv antibody molecules and methods of use thereof
US20040014096A1 (en) 2002-04-12 2004-01-22 Stratagene Dual-labeled nucleotides
US7534580B2 (en) * 2002-05-01 2009-05-19 Ambrilia Biopharma Inc. PSP94 diagnostic reagents and assays
CA2391438A1 (en) * 2002-05-01 2003-11-01 Procyon Biopharma Inc. Psp94 diagnostic reagents and assays
NZ572488A (en) * 2002-05-02 2009-10-30 Univ Wyoming Pregnancy detection
AU2003228809A1 (en) * 2002-05-03 2003-11-17 Sequenom, Inc. Kinase anchor protein muteins, peptides thereof, and related methods
US20040121442A1 (en) * 2002-05-05 2004-06-24 Ilan Chet Fungal chitinase, polynucleotide sequences encoding same, promoters of same, and uses thereof
US20050221349A1 (en) * 2002-05-30 2005-10-06 Stuart Wilson Methods of detecting target molecules and molecular interactions
US7785898B2 (en) * 2002-05-31 2010-08-31 Genetic Technologies Limited Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood
JP4457001B2 (ja) * 2002-05-31 2010-04-28 セクレタリー・デパートメント・オブ・アトミック・エナジー ドナー／アクセプター部分が相補鎖上となる標的核酸検出のｍｅｔ／ｆｒｅｔに基づく方法
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
DE60336023D1 (de) 2002-07-15 2011-03-24 Univ Texas Screening kombinatorischer proteinbibliotheken mittels periplasmatischer expression
NZ537690A (en) 2002-07-15 2009-07-31 Univ Texas Antibodies binding to anionic phospholipids and aminophospholipids and their use in treating viral infections
US7794716B2 (en) 2002-07-25 2010-09-14 Glenveigh Pharmaceuticals, Llc Antibody composition and passive immunization against pregnancy-induced hypertension
EP2561889A3 (en) 2002-08-01 2013-04-03 Yeda Research and Development Co. Ltd. Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels
KR20050062525A (ko) 2002-08-10 2005-06-23 예일 유니버시티 Ｎｏｇｏ 수용체 길항제
JP4694840B2 (ja) 2002-09-09 2011-06-08 アルボー ビータ コーポレーション 子宮頸部癌を検査する方法
AU2003278832A1 (en) * 2002-09-13 2004-04-30 Carnegie Mellon University Optical biosensors and methods of use thereof
US20050042621A1 (en) * 2002-09-27 2005-02-24 Affymetrix, Inc. Method for preparing a nucleic acid sample for hybridization to an array
US7267981B2 (en) 2002-10-07 2007-09-11 Technion Research & Development Foundation Ltd. Human foreskin fibroblasts for culturing ES cells
JP4739755B2 (ja) * 2002-10-11 2011-08-03 ゼットビーエックス コーポレーション 診断装置
JP2006503582A (ja) * 2002-10-21 2006-02-02 ディスカヴァーエックス インコーポレイテッド Ｉｐ３タンパク質結合測定法
WO2004037251A1 (en) 2002-10-24 2004-05-06 Sterix Limited Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 and type 2
US20040146949A1 (en) * 2002-10-25 2004-07-29 Jun Tan Methods and compounds for disruption of CD40R/CD40L signaling in the treatment of alzheimer's disease
EP1578999B1 (en) 2002-10-30 2013-01-16 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Method for measuring non-transferrin bound iron
US20050054097A1 (en) * 2002-11-17 2005-03-10 Tony Peled EX-VIVO expansion of hematopoietic system cell populations in mononuclear cell cultures
FI20022048A0 (fi) * 2002-11-18 2002-11-18 Valtion Teknillinen Ei-kompetetiivinen immunomääritys pienille analyyteille
WO2004047778A1 (en) 2002-11-26 2004-06-10 Uc Tech Materials and methods for preventing and treating microbe-mediated epithelial disorders
US7947499B2 (en) * 2002-11-29 2011-05-24 Technion Research & Development Foundation Ltd. Method of dynamically culturing embryonic stem cells
EP2031070B1 (en) 2002-12-04 2013-07-17 Life Technologies Corporation Multiplex amplification of polynucleotides
US7491699B2 (en) 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
EP1583512B3 (en) 2002-12-12 2012-12-05 R.B.T. (Rakuto Bio Technologies) Ltd. USE of LIGNIN PEROXIDASE IN SKIN AND HAIR LIGHTENING
AU2003303071B2 (en) 2002-12-16 2009-04-23 Technion Research & Development Foundation Ltd. Methods of preparing feeder cells-free, xeno-free human embryonic stem cells and stem cell cultures prepared using same
ATE546548T1 (de) 2003-01-02 2012-03-15 Rappaport Family Inst For Res Verfahren zur prognose des nutzens einer antioxidationshemmenden therapie zur vorbeugung von herz-kreislauf-erkrankungen bei hyperglykämischen patienten
US20040229245A1 (en) * 2003-01-06 2004-11-18 Anton Bittner Methods and algorithms for performing quality control during gene expression profiling on DNA microarray technology
ATE426575T1 (de) 2003-01-07 2009-04-15 Univ Ramot Peptidenanostrukturen die fremdmaterial enthalten,und verfahren zur herstellung derselben
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
DE602004030000D1 (de) * 2003-01-17 2010-12-23 Danisco Verfahren zur in-situ-herstellung eines emulgators in einem nahrungsmittel
DK1748074T3 (da) 2003-01-17 2012-03-05 Danisco Fremgangsmåde til in situ-fremstilling af en emulgator i en fødevare
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
US20050014249A1 (en) * 2003-02-21 2005-01-20 Norbert Staimer Chromatographic analysis on optical bio-discs and methods relating thereto
EP2319857A3 (en) 2003-03-04 2012-06-27 Yeda Research And Development Co., Ltd. Pon polypeptides, polynucleotides encoding same and compositions and methods utilizing same
WO2004078999A1 (en) * 2003-03-05 2004-09-16 Genetic Technologies Limited Identification of fetal dna and fetal cell markers in maternal plasma or serum
EP1601759A4 (en) * 2003-03-07 2007-02-14 Gamida Cell Ltd EXPANSION OF RENEWABLE STEM CELL POPULATIONS USING PI-3 KINASE MODULATORS
KR20060015468A (ko) 2003-03-07 2006-02-17 뉴 잉글랜드 메디컬 센터 호스피털스 인코퍼레이티드 ＩｇＡ1 침착 질환 치료
US8017113B2 (en) 2003-03-12 2011-09-13 Rappaport Family Institute For Research In The Medical Sciences Compositions and methods for diagnosing and treating an inflammation
US7294701B2 (en) * 2003-04-02 2007-11-13 Technion Research & Development Foundation Ltd. Antibody fragment capable of modulating multidrug resistance and compositions and kits and methods using same
ES2369498T3 (es) 2003-04-04 2011-12-01 Yeda Research And Development Co., Ltd. Anticuerpos para inhibir la actividad de mmp-2 y mmp-9.
CA2520023C (en) 2003-04-08 2013-02-05 Yeda Research And Development Co. Ltd Stem cells having increased sensitivity to sdf-1 and methods of generating and using same
FR2853551B1 (fr) 2003-04-09 2006-08-04 Lab Francais Du Fractionnement Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee
US7402386B2 (en) 2003-04-14 2008-07-22 Nugen Technologies, Inc. Global amplification using random priming by a composite primer
BRPI0409562A (pt) * 2003-04-16 2006-04-18 Univ Yale tratamento de condições envolvendo placas amilóides
US7917298B1 (en) 2003-04-17 2011-03-29 Nanosys, Inc. Nanocrystal taggants
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
BRPI0411182B1 (pt) 2003-05-22 2019-08-20 Evogene Ltd. Método para aumentar a tolerância de uma planta ao estresse salino e construto deácido nucleico
US7554007B2 (en) 2003-05-22 2009-06-30 Evogene Ltd. Methods of increasing abiotic stress tolerance and/or biomass in plants
AU2005234725B2 (en) * 2003-05-22 2012-02-23 Evogene Ltd. Methods of Increasing Abiotic Stress Tolerance and/or Biomass in Plants and Plants Generated Thereby
EP1636333A4 (en) * 2003-06-19 2007-10-24 Evogene Ltd NUCLEOTIDE SEQUENCES FOR REGULATING GENE EXPRESSION IN VEGETABLE TRICHROMES, AND HYBRID GENES AND METHODS IN WHICH THEY INTERVENE
US8129514B2 (en) * 2003-06-19 2012-03-06 Evogene Ltd. Nucleotide sequences for regulating gene expression in plant trichomes and constructs and methods utilizing same
AU2004257645A1 (en) * 2003-07-07 2005-01-27 David H. Wagner Methods for predicting development of auto-immune diseases and treatment of same
US20090088337A1 (en) * 2003-07-10 2009-04-02 Ronald Gill RET-Based Analyte Detection
US8454566B2 (en) * 2003-07-10 2013-06-04 Medtronic Minimed, Inc. Methods and compositions for the inhibition of biofilms on medical devices
WO2005014795A2 (en) 2003-08-08 2005-02-17 Genenews Inc. Osteoarthritis biomarkers and uses thereof
US20050064479A1 (en) * 2003-08-12 2005-03-24 Affymetrix, Inc. Compounds and methods for post incorporation labeling of nucleic acids
CN101076585A (zh) * 2003-08-14 2007-11-21 生物平衡公司 细菌株系、包括该细菌株系的组合物和其益生菌用途
AU2004265662B2 (en) 2003-08-14 2010-12-16 Exelixis, Inc. UPs as modifiers of the beta catenin pathway and methods of use
JP4711963B2 (ja) 2003-09-15 2011-06-29 オクラホマ メディカル リサーチ ファウンデーション 炎症性疾患および自己免疫疾患を診断、治療および評価するためにサイトカインアッセイを用いる方法
WO2005050206A2 (en) * 2003-09-17 2005-06-02 Molecular Probes, Inc. Competitive immunoassay
US20050064435A1 (en) * 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
US7625707B2 (en) 2003-10-02 2009-12-01 Ramot At Tel Aviv University Ltd. Antibacterial agents and methods of identifying and utilizing same
CA2541535C (en) 2003-10-07 2013-12-10 Yeda Research And Development Co. Ltd. Antibodies to nik, their preparation and use
IL158287A0 (en) 2003-10-07 2004-05-12 Yeda Res & Dev Antibodies to nik, their preparation and use
US20050227251A1 (en) 2003-10-23 2005-10-13 Robert Darnell Method of purifying RNA binding protein-RNA complexes
CA2542221A1 (en) * 2003-10-23 2005-05-06 Pfizer Products Inc. Vaccine for periodontal disease
CA2544367A1 (en) * 2003-10-29 2005-05-12 Ribomed Biotechnologies, Inc. Compositions, methods and detection technologies for reiterative oligonucleotide synthesis
PE20050925A1 (es) 2003-11-10 2005-11-29 Schering Corp Anticuerpo recombinante humanizado anti-interleuquina 10
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
JP3615752B1 (ja) 2003-11-18 2005-02-02 淳 高橋 細径樹脂捩じりブラシ
ES2469670T3 (es) 2003-11-30 2014-06-18 Yeda Research And Development Co., Ltd. Métodos y agentes para inmunomodulaci�n y métodos para identificar inmunomoduladores
US20050118727A1 (en) * 2003-12-01 2005-06-02 Carsten Schelp Conjugates and their use in detection methods
CA2547351A1 (en) * 2003-12-01 2005-07-07 Dade Behring Marburg Gmbh Homogeneous detection method
WO2005064336A1 (en) * 2003-12-09 2005-07-14 Molecular Probes, Inc. Pyrenyloxysulfonic acid fluorescent agents
US8039642B2 (en) 2003-12-09 2011-10-18 Life Technologies Corporation Pyrenyloxysulfonic acid fluorescent agents
WO2005059100A2 (en) * 2003-12-12 2005-06-30 New York University Methods and compositions relating to cystatin c
US6991911B2 (en) 2003-12-15 2006-01-31 Dade Behring Inc. Assay for entactogens
US20100221233A1 (en) * 2003-12-15 2010-09-02 University Of South Florida Compositions and methods for enhancing neuroprotection via administration of stem cells and blood brain barrier permeabilizers
US7022492B2 (en) 2003-12-15 2006-04-04 Dade Behring Inc. Ecstasy haptens and immunogens
DK1722834T3 (da) 2003-12-22 2012-10-22 Regentis Biomaterials Ltd Matrix, som omfatter naturligt forekommende tværbundet proteinskelet
AU2004308964B2 (en) 2003-12-23 2010-09-16 Arbor Vita Corporation Antibodies for oncogenic strains of HPV and methods of their use
DK2119771T3 (en) 2003-12-24 2018-12-10 Dupont Nutrition Biosci Aps PROTEINS
GB0716126D0 (en) * 2007-08-17 2007-09-26 Danisco Process
US7718408B2 (en) * 2003-12-24 2010-05-18 Danisco A/S Method
US8007847B2 (en) 2004-01-13 2011-08-30 Eytan Biderman Feeding formula appliance
US7423139B2 (en) * 2004-01-20 2008-09-09 Insight Biopharmaceuticals Ltd. High level expression of recombinant human erythropoietin having a modified 5′-UTR
US20050186646A1 (en) * 2004-01-26 2005-08-25 Cruz Miguel A. Rapid assay to detect ADAMTS-13 activity
EP1713900A4 (en) * 2004-01-27 2009-06-17 Compugen Ltd METHOD AND SYSTEMS FOR COMMENTING BIOMOLECULAR SEQUENCES
WO2005079316A2 (en) * 2004-02-18 2005-09-01 Merck & Co., Inc. Nucleic acid molecules encoding novel murine low-voltage activated calcium channel proteins, designated-alpha 1h, encoded proteins and methods of use thereof
DE602005020421D1 (de) 2004-02-19 2010-05-20 Helicos Biosciences Corp Verfahren zur analyse von polynukleotidsequenzen
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
EP2208797A3 (en) 2004-03-01 2010-11-24 Applied Biosystems, LLC Methods, compositions and kits for use in polynucleotide amplification
WO2005084699A1 (en) 2004-03-02 2005-09-15 Acceleron Pharma Inc. Alk7 and myostatin inhibitors and uses thereof
US8352031B2 (en) 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
JP2007533755A (ja) * 2004-04-20 2007-11-22 ザ ユニヴァーシティ オヴ シカゴ 高分子量ｐｅｇ様化合物を含む治療薬送達システム
WO2006083269A2 (en) * 2004-05-14 2006-08-10 Florida Atlantic University Luminescent nanosensors
WO2005113838A2 (en) 2004-05-18 2005-12-01 The Board Of Trustees Of The Leland Stanford Junior University Detection of protein translocation by beta-galactosidase reporter fragment complementation
US7476734B2 (en) 2005-12-06 2009-01-13 Helicos Biosciences Corporation Nucleotide analogs
DE602005027700D1 (de) 2004-05-25 2011-06-09 Helicos Biosciences Corp Verfahren zur nukleinsäureimmobilisierung
EP2583981A3 (en) 2004-05-28 2013-07-31 Agensys, Inc. Antibodies and related molecules that bind to PSCA proteins
BRPI0511395B1 (pt) * 2004-06-14 2019-03-06 Evogene Ltd. Construção de ácido nucléico, e, método de melhoria do rendimento da fibra de uma planta produtora de fibra
US8962915B2 (en) 2004-06-14 2015-02-24 Evogene Ltd. Isolated polypeptides, polynucleotides encoding same, transgenic plants expressing same and methods of using same
US8034553B2 (en) 2004-06-24 2011-10-11 Kimberly-Clark Worldwide, Inc. Biomarkers for wound healing
WO2006004936A2 (en) * 2004-06-30 2006-01-12 Discoverx, Inc. Analysis of intracellular modifications
US8680062B2 (en) * 2004-07-06 2014-03-25 Deliversir Ltd. System for delivering therapeutic agents into living cells and cells nuclei
WO2006010038A2 (en) * 2004-07-08 2006-01-26 Biosearch Technologies, Inc. Inducible fluorescence assay
US20090156471A1 (en) * 2004-07-15 2009-06-18 Ramot At Tel Aviv University Ltd. Use of anti-amyloid agents for treating and typing pathogen infections
WO2006008508A1 (en) 2004-07-16 2006-01-26 Danisco A/S Enzymatic oil-degumming method
US20090035784A1 (en) * 2004-07-30 2009-02-05 Mount Sinai School Of Medicine Of New York University Npc1l1 and npc1l1 inhibitors and methods of use thereof
US20060073168A1 (en) * 2004-08-11 2006-04-06 Stephens David S Neisseria meningitidis serogroup a capsular polysaccharide acetyltransferase, methods and compositions
DE102005026163A1 (de) * 2004-08-24 2006-03-02 Dade Behring Marburg Gmbh Gegen den Marburg I Polymorphismus der Faktor VII aktivierenden Protease (FSAP) gerichtete Antikörper, ihre Herstellung und Verwendung
EP1791959A4 (en) 2004-08-26 2009-03-18 Enegenic Gene Therapy Pty Ltd DISPOSAL OF FUNCTIONAL NUCLEIC ACIDS ON MAMMALIAN CELLS OVER BACTERIA ORIGINAL INTACT MINIMIZERS
FI20050753L (fi) 2004-09-03 2006-03-04 Licentia Oy Uudet peptidit
ATE469245T1 (de) 2004-09-14 2010-06-15 Univ Colorado Auf genetischem targeting basierendes verfahren zur behandlung mit bucindolol
EP1799812A4 (en) 2004-09-16 2009-09-09 Gamida Cell Ltd EX VIVO CULTIVATION METHODS OF STEM CELLS AND PRECURSOR BY CO-CULTURE WITH MESENCHYMAL CELLS
CN101043891A (zh) 2004-09-18 2007-09-26 巴尔的摩马里兰大学 靶向NCCa－ATP通道的治疗剂及其使用方法
JP5085326B2 (ja) 2004-09-18 2012-11-28 ユニバーシティ オブ メリーランド，ボルチモア ＮＣＣａ−ＡＴＰチャネルを標的とする処置剤およびその使用方法
BRPI0516011A (pt) * 2004-09-24 2008-08-19 Amgen Inc moléculas fc modificadas
US20060067889A1 (en) * 2004-09-27 2006-03-30 Light Sciences Corporation Singlet oxygen photosensitizers activated by target binding enhancing the selectivity of targeted PDT agents
CA2582041C (en) * 2004-09-29 2015-08-04 Levava Roiz Recombinant human t2 rnase and uses thereof
EP1809751B1 (en) 2004-09-29 2010-09-01 CollPlant Ltd. Collagen producing plants and methods of generating and using same
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
US7390489B2 (en) * 2004-10-08 2008-06-24 Komed Co., Ltd. Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody
US7781402B2 (en) * 2004-10-12 2010-08-24 Closed Loop Therapies Ltd. Methods and implantable devices for treating supraventricular arrhythmias
GB0423139D0 (en) 2004-10-18 2004-11-17 Danisco Enzymes
WO2006050270A2 (en) * 2004-11-02 2006-05-11 The Government Of The United States Of America As Represented By The Secretary Department Of Health & Human Services Compositions and methods for treating hyperproliferative disorders
GB0424940D0 (en) 2004-11-11 2004-12-15 Danisco Transcription factors
JP2008520583A (ja) * 2004-11-15 2008-06-19 マウント シナイ スクール オブ メディスン オブ ニューヨーク ユニバーシティー Ｗｎｔ自己分泌シグナル伝達を改変するための組成物および方法
IL165484A0 (en) 2004-11-30 2006-01-15 Applied Research Systems Production of proteins
MX2007006640A (es) 2004-12-03 2007-06-19 Schering Corp Biomarcadores para la preseleccion de pacientes para la terapia con anti-receptor 1 del factor de crecimiento similar a la insulina.
US7504769B2 (en) * 2004-12-16 2009-03-17 E. I. Du Pont De Nemours + Company Aromatic chalcogen compounds and their use
US20060134680A1 (en) * 2004-12-22 2006-06-22 Alexander Kotlyar Homogeneous populations of nucleic acids, methods of synthesyzing same and uses thereof
US7220549B2 (en) * 2004-12-30 2007-05-22 Helicos Biosciences Corporation Stabilizing a nucleic acid for nucleic acid sequencing
JP2008527563A (ja) 2005-01-16 2008-07-24 ズランゴー リミテッド アイコニック通信
US8019818B2 (en) 2005-01-18 2011-09-13 Zlango Ltd. Communications network system and methods for using same
US7482120B2 (en) 2005-01-28 2009-01-27 Helicos Biosciences Corporation Methods and compositions for improving fidelity in a nucleic acid synthesis reaction
WO2006080021A2 (en) 2005-01-31 2006-08-03 Realbio Technologies Ltd. Multistep reaction lateral flow capillary device
EP2520669A3 (en) 2005-02-07 2013-02-27 GeneNews Inc. Mild osteoathritis biomarkers and uses thereof
EP1865935B1 (en) 2005-02-17 2011-06-08 Hadasit Medical Research Services and Development Ltd. Bisphosphonates for treating endometriosis
GB0503546D0 (en) * 2005-02-21 2005-03-30 Hellenic Pasteur Inst Antibody
WO2006090388A2 (en) 2005-02-25 2006-08-31 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center Fruit cell culture extract for treating inflammation
US7695927B2 (en) * 2005-03-18 2010-04-13 Detroit R & D Detection of hypertension using glucuronidated metabolic products
NZ562453A (en) 2005-03-31 2010-04-30 Agensys Inc Antibodies and related molecules that bind to 161P2F10B proteins
DK3264094T3 (da) 2005-04-04 2020-11-23 Biogen Ma Inc Fremgangsmåder til evaluering af en immunrespons på et terapeutisk middel
EP1874334A4 (en) * 2005-04-15 2011-03-30 Vascular Biogenics Ltd COMPOSITIONS WITH BETA 2-GLYCOPROTEIN I-PEPTIDES FOR THE PREVENTION AND / OR TREATMENT OF VASCULAR DISEASES
US20130022979A1 (en) 2005-04-18 2013-01-24 Genesis Genomics Inc. 3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER
KR101363032B1 (ko) 2005-04-18 2014-02-13 미토믹스 인크. 일광 노출, 전립선암 및 다른 암의 검출용 진단 도구로서미토콘드리아 돌연변이 및 전위
US8834862B2 (en) * 2005-04-19 2014-09-16 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent
US7189582B2 (en) 2005-04-27 2007-03-13 Dade Behring Inc. Compositions and methods for detection of sirolimus
DE102005022047A1 (de) 2005-05-09 2006-11-30 Dade Behring Marburg Gmbh Bindungspartner des Plazentalen Wachstumsfaktors insbesondere gegen den Plazentalen Wachstumsfaktor gerichtete Antikörper, ihre Herstellung und Verwendung
WO2006126208A2 (en) 2005-05-26 2006-11-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions and methods using same for delivering agents into a target organ protected by a blood barrier
US20070021433A1 (en) 2005-06-03 2007-01-25 Jian-Qiang Fan Pharmacological chaperones for treating obesity
DK1893747T3 (en) 2005-06-16 2014-12-01 Univ Ramot ISOLATED CELLS AND POPULATIONS INCLUDING SUCH CELLS FOR TREATING CNS DISEASES
EP1910572B1 (en) 2005-06-20 2015-12-30 Advanced Cell Diagnostics, Inc. Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations
US20070225242A1 (en) * 2005-06-21 2007-09-27 The Board Of Trustees Of The Leland Stanford Junior University Method and composition for treating and preventing tumor metastasis in vivo
US7695975B2 (en) 2005-06-23 2010-04-13 Siemens Healthcare Diagnostics Inc. Detection of adulterated samples
WO2007007325A2 (en) 2005-07-07 2007-01-18 Fulcrum Sp Ltd. Sp1 polypeptides, modified sp1 polypeptides and uses thereof
JP5383186B2 (ja) 2005-07-07 2014-01-08 イッサム リサーチ ディベロプメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム リミテッド Ｈ１９をダウンレギュレートする核酸薬剤、及びそれを使用する方法
CN101278052A (zh) 2005-07-18 2008-10-01 普罗塔里克斯有限公司 生物活性大分子的粘膜或肠给药
WO2007019541A2 (en) * 2005-08-08 2007-02-15 Onconon, Llc. Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
US8916147B2 (en) 2005-08-24 2014-12-23 Yeda Research and Devolpment Co. Ltd. Universal donor-derived tolerogenic cells for inducing non-syngeneic transplantation tolerance
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
EP1962719A4 (en) 2005-08-29 2011-05-04 Technion Res And Dev Of Foundation Ltd MEDIA FOR BREEDING STEM CELLS
PL1931710T3 (pl) 2005-08-31 2017-06-30 Merck Sharp & Dohme Corp. Przeciwciała anty-il-23 skonstruowane techniką inżynierii genetycznej
WO2007030759A2 (en) 2005-09-07 2007-03-15 Nugen Technologies, Inc. Improved nucleic acid amplification procedure
US7608395B2 (en) 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
ATE466079T1 (de) * 2005-09-22 2010-05-15 Yissum Res Dev Co Nukleinsäure konstrukten, pharmazeutische kompositionen und methoden für die behandlung von krebs
WO2007038659A1 (en) * 2005-09-26 2007-04-05 Invitrogen Corporation Violet laser excitable dyes and their method of use
WO2007041340A2 (en) * 2005-09-30 2007-04-12 The Trustees Of Columbia University In The City Of New York Microfluidic cells with parallel arrays of individual dna molecules
US20070202515A1 (en) * 2005-10-12 2007-08-30 Pathologica, Llc. Promac signature application
US20070087437A1 (en) * 2005-10-14 2007-04-19 Jifan Hu Methods for rejuvenating cells in vitro and in vivo
EP2319941A3 (en) 2005-10-21 2011-08-17 GeneNews Inc. Method and apparatus for correlating levels of biomarker products with disease
JP2009512460A (ja) * 2005-10-24 2009-03-26 ディスカヴァーエックス インコーポレイテッド 細胞内の酵素複合体の検出方法
US7842823B2 (en) * 2005-10-27 2010-11-30 The Regents Of The University Of California Fluorogenic probes for reactive oxygen species
EP1948674A4 (en) 2005-11-02 2009-02-04 Protiva Biotherapeutics Inc MODIFIED SIRNA MOLECULES AND APPLICATIONS THEREOF
AU2006311661B2 (en) 2005-11-07 2011-05-26 The Scripps Research Institute Compositions and methods for controlling tissue factor signaling specificity
DE212006000071U1 (de) 2005-11-18 2008-07-24 Board of Regents, The University of Texas System, Austin Quantifizierung von Fusionsproteinen und ihrer Aktivität in Folge chromosomaler Translokation
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
ES2409128T3 (es) 2005-11-29 2013-06-25 Gamida Cell Ltd. Procedimientos de mejora de anidamiento e injerto de células madre
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
US9056291B2 (en) 2005-11-30 2015-06-16 Micronics, Inc. Microfluidic reactor system
WO2008002462A2 (en) * 2006-06-23 2008-01-03 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
AU2006321602B2 (en) 2005-12-08 2012-03-08 Novartis Ag Effects of inhibitors of FGFR3 on gene transcription
US20070134814A1 (en) * 2005-12-09 2007-06-14 Kajander E O Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease
EP2674440B1 (en) 2005-12-16 2019-07-03 IBC Pharmaceuticals, Inc. Multivalent immunoglobulin-based bioactive assemblies
SG163525A1 (en) * 2005-12-23 2010-08-30 Partnership & Corp Technology Synthetic peptides for use as inhibitors of neurotransmitter secretion and as inducers of muscle relaxation
US7465544B2 (en) * 2006-01-11 2008-12-16 Wisconsin Alumni Research Foundation Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use
US8775526B2 (en) 2006-01-16 2014-07-08 Zlango Ltd. Iconic communication
CN101420977B (zh) 2006-01-27 2016-08-10 比奥根Ma公司 Nogo受体拮抗剂
TW200738752A (en) 2006-01-31 2007-10-16 Bayer Schering Pharma Ag Modulation of MDL-1 activity for treatment of inflammatory disease
US7553941B2 (en) 2006-02-03 2009-06-30 Modigene Inc Long-acting polypeptides and methods of producing same
US8048849B2 (en) 2006-02-03 2011-11-01 Modigene, Inc. Long-acting polypeptides and methods of producing same
US9249407B2 (en) 2006-02-03 2016-02-02 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US20150038413A1 (en) 2006-02-03 2015-02-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US10221228B2 (en) 2006-02-03 2019-03-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US9458444B2 (en) 2006-02-03 2016-10-04 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US8048848B2 (en) 2006-02-03 2011-11-01 Prolor Biotech Ltd. Long-acting interferons and derivatives thereof and methods thereof
US20140113860A1 (en) 2006-02-03 2014-04-24 Prolor Biotech Ltd. Long-acting polypeptides and methods of producing and administering same
US8946155B2 (en) 2006-02-03 2015-02-03 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US10351615B2 (en) 2006-02-03 2019-07-16 Opko Biologics Ltd. Methods of treatment with long-acting growth hormone
US8759292B2 (en) 2006-02-03 2014-06-24 Prolor Biotech, Llc Long-acting coagulation factors and methods of producing same
US8450269B2 (en) 2006-02-03 2013-05-28 Prolor Biotech Ltd. Long-acting growth hormone and methods of producing same
US8476234B2 (en) 2006-02-03 2013-07-02 Prolor Biotech Inc. Long-acting coagulation factors and methods of producing same
EP1989554A1 (en) 2006-02-06 2008-11-12 Rappaport Family Institute For Research in the Medical Sciences Methods and kit for diagnosing t1dm
JP5706602B2 (ja) 2006-02-08 2015-04-22 ジェンザイム・コーポレーション ニーマンピック病ａ型に対する遺伝子治療
LT2676967T (lt) 2006-02-28 2019-09-10 Biogen Ma Inc. Uždegiminių ir autoimuninių ligų gydymo būdai su natalizumabu
ES2663377T3 (es) 2006-03-03 2018-04-12 Biogen Ma Inc. Métodos para el tratamiento de enfermedades inflamatorias y autoinmunes con natalizumab
WO2007102146A2 (en) 2006-03-06 2007-09-13 Zetiq Technologies Ltd. Methods and compositions for identifying a cell phenotype
US7397546B2 (en) 2006-03-08 2008-07-08 Helicos Biosciences Corporation Systems and methods for reducing detected intensity non-uniformity in a laser beam
WO2007109733A2 (en) 2006-03-21 2007-09-27 The Johns Hopkins University Diagnostic and prognostic markers and treatment strategies for multiple sclerosis
ES2572214T3 (es) 2006-03-23 2016-05-30 Pluristem Ltd Métodos para expansión celular y usos de células y medios acondicionados producidos de este modo para terapia
EP2004858A4 (en) 2006-03-28 2009-12-09 Tel Hashomer Medical Res Infrastructure & Services Ltd METHOD AND KITS FOR DETERMINING AN INVESTMENT TO WARFARINE RESISTANCE
US20070232556A1 (en) * 2006-03-31 2007-10-04 Montine Thomas J Methods and compositions for the treatment of neurological diseases and disorders
KR20090029184A (ko) * 2006-04-07 2009-03-20 더 가브먼트 오브 더 유나이티드 스테이츠 오브 아메리카, 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 항체 조성물 및 신생물성 질병의 치료 방법
US8841134B2 (en) * 2006-04-10 2014-09-23 Bruker Biospin Corporation Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications
US20070281363A1 (en) * 2006-04-13 2007-12-06 Ewald Terpetschnig Luminescent compounds
FR2900341B1 (fr) 2006-04-27 2012-09-14 Centre Nat Rech Scient Utilisation de ligands synthetiques multivalents de la nucleoline de surface pour le traitement du cancer
US7799534B2 (en) 2006-05-09 2010-09-21 Beckman Coulter, Inc. Nonseparation assay methods
JP2009536739A (ja) * 2006-05-09 2009-10-15 エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント プロテアーゼおよびプロテアーゼ阻害剤の血漿プロファイリングによる拡張期心不全の検出
US7732153B2 (en) 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
US20100196336A1 (en) 2006-05-23 2010-08-05 Dongsu Park Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
US20080076188A1 (en) * 2006-06-19 2008-03-27 Patsenker Leonid D Luminescent compounds
WO2008002920A2 (en) * 2006-06-26 2008-01-03 Epoch Biosciences, Inc. Methods for generating target nucleic acid sequences
JP5385135B2 (ja) 2006-07-03 2014-01-08 チャールズ デイビッド アデア， 細胞接着分子の発現を調節するための組成物
US8557601B2 (en) 2006-07-10 2013-10-15 The Regents Of The University Of California Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides
US20080026394A1 (en) * 2006-07-11 2008-01-31 Antara Biosciences Inc. Methods of detecting one or more cancer markers
JP2009544013A (ja) * 2006-07-11 2009-12-10 エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント プロテアーゼおよびプロテアーゼ阻害因子のプロファイリングによる心筋梗塞後の心不全の予測
EP2046762B1 (en) 2006-07-14 2011-02-16 ChemoCentryx, Inc. Triazolyl phenyl benzenesulfonamides
US8629259B2 (en) 2006-07-20 2014-01-14 Yeda Research And Development Co. Ltd. Photosynthetic organisms and compositions and methods of generating same
WO2008021954A2 (en) * 2006-08-09 2008-02-21 Biogen Idec Ma Inc. Method for distribution of a drug
JP5352460B2 (ja) 2006-08-15 2013-11-27 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ルミネッセント大環状ランタニド錯体
JP2008043332A (ja) 2006-08-17 2008-02-28 Panomics Inc 組織スライドからの核酸定量
WO2008023840A2 (en) 2006-08-25 2008-02-28 Oncotherapy Science, Inc. Prognostic markers and therapeutic targets for lung cancer
EP2064319B1 (en) 2006-08-28 2017-02-22 Yeda Research and Development Co. Ltd. Methods of generating glial and neuronal cells and use of same for the treatment of medical conditions of the cns
JP2008111824A (ja) * 2006-09-01 2008-05-15 Nox Technologies Inc 腫瘍特異的ｔＮＯＸアイソフォーム及び方法
US7951776B2 (en) 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
US7985542B2 (en) * 2006-09-07 2011-07-26 Institut Pasteur Genomic morse code
US7569396B1 (en) 2006-09-08 2009-08-04 Purplecow Llc Caffeine detection using internally referenced competitive assays
ES2431144T3 (es) 2006-09-08 2013-11-25 University Of Oxford Diagnóstico clínico de una fibrosis hepática utilizando la cadena pesada H4 de inhibidor de inter-alfa-tripsina
US8050516B2 (en) * 2006-09-13 2011-11-01 Fluidigm Corporation Methods and systems for determining a baseline during image processing
US8055034B2 (en) 2006-09-13 2011-11-08 Fluidigm Corporation Methods and systems for image processing of microfluidic devices
AU2007303821B9 (en) 2006-10-05 2013-06-20 Technion Research & Development Foundation Ltd. Microtubes and methods of producing same
US7888059B2 (en) * 2006-10-05 2011-02-15 Yeda Research And Development Co. Ltd. Highly purified and stabilized Na,K-ATPase isoforms and methods of producing same
ES2400676T3 (es) * 2006-10-11 2013-04-11 Janssen Pharmaceutica Nv Composiciones y métodos para el tratamiento y el diagnóstico de síndrome de intestino irritable
EP1912067A1 (en) * 2006-10-12 2008-04-16 Eppendorf Array Technologies S.A. Method for quantification of a target compound obtained from a biological sample upon chips
WO2008051491A2 (en) 2006-10-20 2008-05-02 Danisco Us, Inc. Genencor Division Polyol oxidases
US20080305512A1 (en) * 2006-10-26 2008-12-11 Mattingly Phillip G Assay for cardiac troponin autoantibodies
US7776605B2 (en) 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
CA2667012A1 (en) * 2006-10-26 2008-05-02 Abbott Laboratories Immunoassay of analytes in samples containing endogenous anti-analyte antibodies
JP2010507384A (ja) 2006-10-27 2010-03-11 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ キナーゼ阻害剤のプロファイリング方法
WO2008066655A2 (en) 2006-11-02 2008-06-05 Yale University Assessment of oocyte competence
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
CA2671264C (en) 2006-11-30 2015-11-24 Research Development Foundation Improved immunoglobulin libraries
WO2008067552A2 (en) * 2006-11-30 2008-06-05 Fluidigm Corporation Method and apparatus for biological sample analysis
EP2628752A1 (en) 2006-12-14 2013-08-21 Merck Sharp & Dohme Corp. Engineered anti-TSLP antibody
AU2007335706B2 (en) 2006-12-20 2013-03-28 Evogene Ltd. Polynucleotides and polypeptides involved in plant fiber development and methods of using same
US8506499B2 (en) * 2007-01-04 2013-08-13 Musc Foundation For Research Development Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling
WO2008084405A2 (en) * 2007-01-11 2008-07-17 Erasmus University Medical Center Circular chromosome conformation capture (4c)
US9511075B2 (en) 2007-01-12 2016-12-06 The University Of Maryland, Baltimore Targeting NCCA-ATP channel for organ protection following ischemic episode
US20100086526A1 (en) * 2007-01-16 2010-04-08 Abraham Hochberg Nucleic acid constructs and methods for specific silencing of h19
AU2007344910B2 (en) 2007-01-25 2013-03-28 Dupont Nutrition Biosciences Aps Production of a lipid acyltransferase from transformed Bacillus licheniformis cells
CN101657719A (zh) 2007-01-26 2010-02-24 路易斯维尔大学研究基金会公司 检测用于诊断和表征障碍的自身抗体的方法
WO2008093331A1 (en) * 2007-01-29 2008-08-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Antibody conjugates for circumventing multi-drug resistance
WO2008093341A2 (en) 2007-01-31 2008-08-07 Technion Research & Development Foundation Ltd. Electrospun scaffolds and methods of generating and using same
EP2478924A1 (en) 2007-02-01 2012-07-25 Technion Research & Development Foundation Albumin fibers and fabrics and methods of generating and using same
PE20090722A1 (es) 2007-02-02 2009-07-13 Amgen Inc Hepcidina, antagonistas de la hepcidina y metodos de uso
US8838195B2 (en) 2007-02-06 2014-09-16 Medtronic Minimed, Inc. Optical systems and methods for ratiometric measurement of blood glucose concentration
US7751863B2 (en) 2007-02-06 2010-07-06 Glumetrics, Inc. Optical determination of ph and glucose
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
KR100855299B1 (ko) * 2007-02-16 2008-08-29 건국대학교 산학협력단 인간 ｉｌ-32 특이 항원결정기를 갖는 단일클론항체,특이항체분비 융합 세포주 및 항체들을 이용한 ｉｌ-32측정법
BRPI0807710B1 (pt) 2007-02-23 2021-12-14 Merck Sharp & Dohme Corp Anticorpos que se ligam a il-23p19 e il-23 humana, anticorpo, ácido nucleico isolado, vetor de expressão, célula hospedeira microbiana, método de produção de um polipeptídeo e composição farmacêutica
SG178804A1 (en) 2007-02-23 2012-03-29 Schering Corp Engineered anti-il-23p19 antibodies
JP5238723B2 (ja) 2007-02-28 2013-07-17 メルク・シャープ・アンド・ドーム・コーポレーション 操作された抗ｉｌ−２３ｒ抗体
EP2134373A4 (en) 2007-02-28 2014-04-02 Yeda Res & Dev CORE TARGETING SEQUENCES
US20100216654A1 (en) 2007-03-12 2010-08-26 Miraculins, Inc. Biomarkers of prostate cancer and uses thereof
EP2514766A3 (en) 2007-03-29 2013-06-05 Technion Research & Development Foundation Ltd. Antibodies, methods and kits for diagnosing and treating melanoma
CN105854029B (zh) 2007-03-30 2019-10-18 因詹尼克分子递送控股有限公司 用于体内递送至哺乳动物细胞的、包含无质粒的功能性核酸的、源自细菌的完整小细胞
CN101702920B (zh) 2007-04-02 2013-03-13 特拉维夫大学拉莫特有限公司 癌细胞的检测方法及其在诊断和监测疾病治疗中的应用
US7968292B2 (en) 2007-04-06 2011-06-28 Becton, Dickinson And Company Compositions and methods for the identification of a carbapenemase gene
WO2008122980A2 (en) 2007-04-09 2008-10-16 Evogene Ltd. Polynucleotides, polypeptides and methods for increasing oil content, growth rate and biomass of plants
CA2683559C (en) 2007-04-13 2019-09-24 Dana Farber Cancer Institute, Inc. Methods for treating cancer resistant to erbb therapeutics
US8003314B2 (en) 2007-04-16 2011-08-23 Diagnostic Hybrids, Inc. Methods for direct fluorescent antibody virus detection in liquids
PT2144633E (pt) * 2007-04-23 2014-10-27 Deliversir Ltd Um sistema para a administração de agentes terapêuticos em células vivas e núcleos de células
US9156865B2 (en) 2007-04-23 2015-10-13 Deliversir Ltd System for delivering therapeutic agents into living cells and cells nuclei
WO2014064687A1 (en) 2012-10-22 2014-05-01 Deliversir Ltd A system for delivering therapeutic agents into living cells and cells nuclei
US9556210B2 (en) 2007-04-23 2017-01-31 Sabag-Rfa Ltd. System for delivering therapeutic agents into living cells and cells nuclei
ES2564312T3 (es) 2007-05-01 2016-03-21 Tel Hashomer Medical Research Infrastructure And Services Ltd. Métodos y kits para detectar células fetales en la sangre materna
AU2008247819B2 (en) 2007-05-01 2013-02-14 Research Development Foundation Immunoglobulin Fc libraries
AU2008275513A1 (en) * 2007-05-02 2009-01-15 Emory University Enhancement of glycoprotein incorporation into virus-like particles
SG10201507845PA (en) 2007-05-03 2015-10-29 Agency Science Tech & Res Antibodies binding to an intracellular prl-1 or prl-3 polypeptide
WO2008135991A2 (en) 2007-05-07 2008-11-13 Protalix Ltd. Large scale disposable bioreactor
EP2162057A1 (en) * 2007-05-10 2010-03-17 Glumetrics, Inc. Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement
WO2008150496A2 (en) * 2007-05-31 2008-12-11 Genelux Corporation Assay for sensitivity to chemotherapeutic agents
US7776877B2 (en) * 2007-06-22 2010-08-17 Chemocentryx, Inc. N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
WO2009000089A1 (en) * 2007-06-28 2008-12-31 University Of Saskatchewan Immunomodulatory compositions and methods for treating disease with modified host defense peptides
EP2500428A3 (en) 2007-07-11 2012-12-26 Yeda Research and Development Co. Ltd. Nucleic acid construct systems capable of diagnosing or treating a cell state
CA2692761C (en) 2007-07-12 2013-04-30 Chemocentryx, Inc. Fused heteroaryl pyridyl and phenyl benzenesulfonamides as ccr2 modulators for the treament of inflammation
WO2009010968A2 (en) 2007-07-15 2009-01-22 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
IL184627A0 (en) 2007-07-15 2008-12-29 Technion Res & Dev Foundation Agents for diagnosing and modulating metastasis and fibrosis as well as inflammation in a mammalian tissue
BRPI0812742B1 (pt) 2007-07-24 2021-04-20 Evogene Ltd método de aumento da biomassa, da taxa de crescimento, da produtividade de semente, da eficiência do uso de nitrogênio, do estresse abiótico de uma planta, do comprimento de raiz, da cobertura de raiz, da taxa de crescimento da área de roseta, e da taxa de crescimento do diâmetro da roseta de uma planta
US8293685B2 (en) 2007-07-26 2012-10-23 The Regents Of The University Of California Methods for enhancing bacterial cell display of proteins and peptides
HUE025283T2 (en) 2007-08-02 2016-03-29 Gilead Biologics Inc LOX and LOX2 inhibitors and their use
US8715743B2 (en) 2007-08-03 2014-05-06 Musc Foundation For Research Development Human monoclonal antibodies and methods for producing the same
US7790401B2 (en) 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
WO2009021054A2 (en) 2007-08-06 2009-02-12 Orion Genomics Llc Novel single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the igf2 gene
JP5548616B2 (ja) 2007-08-08 2014-07-16 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム Ｖｅｇｆｒ−１／ｎｒｐ−１標的化ペプチド
WO2009023676A1 (en) 2007-08-12 2009-02-19 Integrated Dna Technologies, Inc. Microarray system with improved sequence specificity
WO2009023733A1 (en) * 2007-08-13 2009-02-19 Trustees Of Tufts College Methods and microarrays for detecting enteric viruses
US20110052572A1 (en) 2007-08-15 2011-03-03 Yeda Research And Development Co. Ltd Regulators of mmp-9 and uses therof
AU2008299318A1 (en) 2007-09-12 2009-03-19 The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center Methods of treating tumors in immune-privileged sites
EP2591789B2 (en) 2007-09-19 2022-07-20 Pluristem Ltd. Adherent cells from adipose or placenta tissues and use thereof in therapy
EP2511708B1 (en) 2007-10-05 2016-09-14 Affymetrix, Inc. Highly multiplexed particle-based assays
US7771960B2 (en) * 2007-10-15 2010-08-10 Idexx Laboratories, Inc. Feline pancreatic lipase
AU2008313274A1 (en) 2007-10-19 2009-04-23 Rappaport Family Institute For Research In The Medical Sciences Compositions comprising semaphorins for the treatment of angiogenesis related diseases and methods of selection thereof
WO2009062027A1 (en) * 2007-11-07 2009-05-14 Beckman Coulter, Inc. Nonseparation assay methods using peroxide generating enzymes
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
JP5631215B2 (ja) 2007-11-21 2014-11-26 メドトロニック ミニメド インコーポレイテッド 血糖管理維持システム
JP5264421B2 (ja) * 2007-11-22 2013-08-14 富士フイルム株式会社 被験物測定用担体およびその製造方法
AU2008331099B2 (en) 2007-11-26 2013-10-24 Collplant Ltd. Compositions comprising fibrous polypeptides and polysaccharides
US7910378B2 (en) 2007-12-14 2011-03-22 Siemens Healthcare Diagnostics Inc. Methods for detection of hydrophobic drugs
EP2238251B1 (en) 2007-12-27 2015-02-11 Protiva Biotherapeutics Inc. Silencing of polo-like kinase expression using interfering rna
CN101977928B (zh) 2007-12-27 2014-12-10 伊沃基因有限公司 用于改进植物的水分利用效率、肥料利用效率、生物/非生物胁迫耐受性、产量和生物量的分离多肽、多核苷酸
WO2009102509A2 (en) 2008-01-10 2009-08-20 Research Development Foundation Vaccines and diagnostics for the ehrlichioses
WO2009094551A1 (en) 2008-01-25 2009-07-30 Amgen Inc. Ferroportin antibodies and methods of use
WO2009095925A2 (en) * 2008-01-31 2009-08-06 Compugen Ltd. Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
EP3441079A1 (en) 2008-02-07 2019-02-13 Cornell University Methods for preventing or treating insulin resistance
US20090203531A1 (en) 2008-02-12 2009-08-13 Nurith Kurn Method for Archiving and Clonal Expansion
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
US9464368B2 (en) 2008-02-21 2016-10-11 Technion Research & Development Foundation Ltd. Methods of attaching a molecule-of-interest to a microtube
US20090311695A1 (en) * 2008-03-12 2009-12-17 Talat Nasim Method
US7846666B2 (en) 2008-03-21 2010-12-07 Nugen Technologies, Inc. Methods of RNA amplification in the presence of DNA
NZ588658A (en) * 2008-03-28 2012-10-26 Mitomics Inc Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor
EP2107125A1 (en) 2008-03-31 2009-10-07 Eppendorf Array Technologies SA (EAT) Real-time PCR of targets on a micro-array
JP5669721B2 (ja) 2008-04-01 2015-02-12 バイオサーチ テクノロジーズ，インコーポレイテッド 安定化核酸ダーククエンチャー−フルオロフォアプローブ
EP2770057A1 (en) 2008-04-15 2014-08-27 Protiva Biotherapeutics Inc. Silencing of CSN5 gene expression using interfering RNA
ES2638448T3 (es) 2008-04-15 2017-10-20 Protiva Biotherapeutics Inc. Novedosas formulaciones de lípidos para la administración de ácidos nucleicos
WO2009129186A2 (en) 2008-04-17 2009-10-22 Glumetrics, Inc. Sensor for percutaneous intravascular deployment without an indwelling cannula
CN102056619A (zh) 2008-04-18 2011-05-11 科尔普兰特有限公司 产生和使用原胶原的方法
CA2721372A1 (en) 2008-04-21 2009-10-29 Danziger Innovations Ltd. Plant viral expression vectors and use of same for generating genotypic variations in plant genomes
JP2011519034A (ja) * 2008-04-23 2011-06-30 ルミネックス コーポレーション 生物学的起原の出発材料中に見出される複数の検体のスタンダードを作成する方法
JP2012500620A (ja) 2008-04-24 2012-01-12 ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク Ｄｎａ分子組織化のための幾何学的パターンおよび脂質二重層、ならびにその使用
DK2281034T3 (en) 2008-04-30 2016-01-25 Dupont Nutrition Biosci Aps A method using alcohol dehydrogenase Pseudoglucanobacter saccharoketogenes
EP2294087B1 (en) 2008-05-01 2014-05-14 Amgen, Inc. Anti-hepcidin antibodies and methods of use
EP2116618A1 (en) 2008-05-09 2009-11-11 Agency for Science, Technology And Research Diagnosis and treatment of Kawasaki disease
WO2009140666A2 (en) 2008-05-15 2009-11-19 Ribomed Biotechnologies, Inc. METHODS AND REAGENTS FOR DETECTING CpG METHYLATION WITH A METHYL CpG BINDING PROTEIN (MBP)
CN102037005B (zh) * 2008-05-22 2017-03-29 国家科学研究中心 改善治疗功效的新光学纯化合物
US8847008B2 (en) 2008-05-22 2014-09-30 Evogene Ltd. Isolated polynucleotides and polypeptides and methods of using same for increasing plant utility
BRPI0909541A2 (pt) 2008-05-27 2016-10-11 Pluristem Ltd ''método para tratamento de doenças inflamatórias do cólon''
ES2729557T3 (es) 2008-05-28 2019-11-04 Univ Ramot Células madre mesenquimatosas para el tratamiento de enfermedades del SNC
WO2009152102A2 (en) * 2008-06-10 2009-12-17 The Regents Of The University Of California Pro-fluorescent probes
FI20085579A0 (fi) * 2008-06-12 2008-06-12 Valtion Teknillinen Kannabiskäytön toteaminen
CN102076415B (zh) 2008-06-29 2015-06-24 瑞尔比奥技术有限公司 尤其可用作生物测定过程中的捕捉装置的液体转移装置
US8211644B2 (en) * 2008-07-13 2012-07-03 Ribomed Biotechnologies, Inc. Molecular beacon-based methods for detection of targets using abscription
EP2657342B1 (en) 2008-08-08 2015-11-18 Genisphere, LLC DNA dendrimers protected against nuclease degradation
CN102176914B (zh) 2008-08-08 2014-12-17 新加坡科技研究局 用于诊断和治疗癌症的vhz
US20120034155A1 (en) * 2010-08-03 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Artificial cells
AR073076A1 (es) 2008-08-18 2010-10-13 Evogene Ltd Polipeptidos y polinucleotidos aislados utiles para mejorar la eficacia en el uso de nitrogeno, tolerancia al estres abiotico, rendimiento y biomasa en plantas.
SG190659A1 (en) 2008-09-02 2013-06-28 Pluristem Ltd Adherent cells from placenta tissue and use thereof in therapy
US8367392B2 (en) * 2008-09-05 2013-02-05 Transalgae Ltd. Genetic transformation of algal and cyanobacteria cells by microporation
US8583380B2 (en) 2008-09-05 2013-11-12 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
US20110305682A1 (en) 2008-09-11 2011-12-15 Ben Gurion University Of The Negev Research And Development Authority Compositions and Methods for Treating S. Pneumonia Infection
JP6105846B2 (ja) 2008-09-12 2017-03-29 クライオプラキス クライオバイオロヒア エリテーデーアー． 虚血組織の細胞療法
SG10201504623VA (en) 2008-09-24 2015-07-30 Tel Hashomer Medical Res Infrastructure & Services Ltd Peptides and compositions for prevention of cell adhesion and methods of using same
US9434985B2 (en) 2008-09-25 2016-09-06 University Of Massachusetts Methods of identifying interactions between genomic loci
US20110178024A1 (en) 2008-09-29 2011-07-21 Ben Gurion University Of The Negev Research And Development Authority Amyloid beta-peptides and methods of use thereof
DE102008049601A1 (de) 2008-09-30 2010-04-01 Siemens Healthcare Diagnostics Products Gmbh Antikörper zur Bestimmung des Prothrombin-Fragments F2/F1+2 in einem homogenen Immunoassay
EP2347014B1 (en) 2008-10-30 2016-09-21 Evogene Ltd. Isolated polynucleotides and polypeptides and methods of using same for increasing plant yield, biomass, growth rate, vigor, oil content, abiotic stress tolerance of plants and nitrogen use efficieny
EP2350131B1 (en) 2008-11-07 2017-06-07 Research Development Foundation Compositions and methods for the inhibition of cripto/grp78 complex formation and signaling
US20110229892A1 (en) 2008-11-17 2011-09-22 Yehuda G Assaraf Method for predicting a patient's responsiveness to anti-folate therapy
WO2010058396A1 (en) 2008-11-19 2010-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. A cd44vra antibody and diagnostic and therapeutic methods using same
WO2010061383A1 (en) 2008-11-26 2010-06-03 Biodalia Microbiological Technologies Ltd. A method of in-situ enrichment of foods with fructan
WO2010064231A1 (en) 2008-12-02 2010-06-10 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods of analyzing a-i rna editing and nucleic acid constructs capable of same
CA2745111A1 (en) 2008-12-03 2010-06-10 Research Development Foundation Modulation of olfml-3 mediated angiogenesis
US20120014927A1 (en) 2008-12-03 2012-01-19 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods and kits for determining predisposition to cancer
EP2373301B1 (en) 2008-12-05 2013-11-06 Yeda Research and Development Co. Ltd. Methods of diagnosing motor neuron diseases
JP2012511032A (ja) 2008-12-05 2012-05-17 アブラクシス バイオサイエンス リミテッド ライアビリティー カンパニー ＳＰＡＲＣ結合ＳｃＦｖ
WO2010066252A1 (en) 2008-12-09 2010-06-17 Dako Denmark A/S Method for evaluating pre-treatment
WO2010068757A1 (en) 2008-12-12 2010-06-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and methods useful for detecting and treating diseases associated with 16p chromosomal disruptions
WO2010071610A1 (en) 2008-12-19 2010-06-24 Agency For Science, Technology And Research (A*Star) Severe chikungunya biomarkers
CA2967412C (en) 2008-12-29 2018-07-17 Tel Hashomer Medical Research, Infrastructure And Services Ltd. Peptides and compositions for prevention of cell adhesion and methods of using same
AR074925A1 (es) 2008-12-29 2011-02-23 Evogene Ltd Polinucleotidos, polipeptidos codificados, y metodos para utilizarlos para modular la tolerancia al estres abiotico, biomasa y/o rendimiento en plantas que los expresan
WO2010076788A2 (en) 2008-12-29 2010-07-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of predicting responsiveness to interferon treatment and treating hepatitis c infection
US8455263B2 (en) 2008-12-30 2013-06-04 Jin Po Lee Quantitative analyte assay device and method
WO2010076794A1 (en) 2008-12-31 2010-07-08 Technion Research & Development Foundation Ltd. Method of denitrifying brine and systems capable of same
WO2010080769A2 (en) 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Chemotherapeutic methods and compositions
IL196820A0 (en) 2009-02-01 2009-11-18 Yissum Res Dev Co Devitalized, acellular scaffold matrices derived from micro-organs seeded with various cells
EP2391377A2 (en) 2009-02-02 2011-12-07 Ramot at Tel-Aviv University Ltd. Peptides, pharmaceutical compositions comprising same and uses thereof
WO2010089707A1 (en) 2009-02-04 2010-08-12 Yeda Research And Development Co. Ltd. Methods and kits for determining sensitivity or resistance of prostate cancer to radiation therapy
CN102439454B (zh) 2009-02-11 2015-05-13 卡里斯Mpi公司 肿瘤的分子谱分析
ES2544265T3 (es) 2009-02-11 2015-08-28 Orion Genomics, Llc Combinaciones de polimorfismos para determinar la expresión específica de alelo de IGF2
US20110306069A1 (en) 2009-02-19 2011-12-15 Qingyu Wu Corin As A Marker For Heart Failure
EP2401362B1 (en) 2009-02-26 2017-04-12 Tel HaShomer Medical Research Infrastructure and Services Ltd. Isolated populations of renal stem cells and methods of isolating and using same
MX377436B (es) 2009-03-02 2025-03-10 Evogene Ltd Polinucleotidos y polipeptidos aislados, y metodos para usarlos para incrementar el rendimiento de una planta y/o caracteristicas agricolas.
EP2404162B1 (en) 2009-03-03 2017-12-27 Access Medical System Co., Ltd. Detection system and method for high sensitivity fluorescent assays
PL2406279T3 (pl) 2009-03-09 2016-07-29 Univ Ramot Kompozycje do zapobiegania i leczenia chorób neurodegeneratywnych.
WO2010103517A1 (en) 2009-03-12 2010-09-16 Rappaport Family Institute For Research In The Medical Sciences Soluble compositions for the treatment of cxcr3-ligand associated diseases
US9347947B2 (en) * 2009-03-12 2016-05-24 Siemens Healthcare Diagnostics Inc. Immunoassays employing non-particulate chemiluminescent reagent
AU2010225937B2 (en) 2009-03-15 2014-09-18 Ribomed Biotechnologies, Inc. Abscription based molecular detection
US20100240065A1 (en) * 2009-03-18 2010-09-23 Boehringer Ingelheim International Gmbh Prolyl Hydroxylase Compositions and Methods of Use Thereof
US8481698B2 (en) * 2009-03-19 2013-07-09 The President And Fellows Of Harvard College Parallel proximity ligation event analysis
US9464319B2 (en) 2009-03-24 2016-10-11 California Institute Of Technology Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes
US9447461B2 (en) 2009-03-24 2016-09-20 California Institute Of Technology Analysis devices, kits, and related methods for digital quantification of nucleic acids and other analytes
KR101796906B1 (ko) 2009-03-24 2017-11-10 유니버시티 오브 시카고 반응을 수행하기 위한 방법
US10196700B2 (en) 2009-03-24 2019-02-05 University Of Chicago Multivolume devices, kits and related methods for quantification and detection of nucleic acids and other analytes
JP5911421B2 (ja) * 2009-03-27 2016-05-18 ゴジョ・インダストリーズ・インコーポレイテッド 組成物及び胞子−表面の相互作用と拮抗する化合物をスクリーニングする方法及び使用する方法
JP5734947B2 (ja) 2009-03-27 2015-06-17 ミトミクス インコーポレイテッドＧｅｎｅｓｉｓ Ｇｅｎｏｍｉｃｓ Ｉｎｃ． 異常型ミトコンドリアｄｎａ、関連融合転写物および翻訳産物、並びにそのハイブリダイゼーションプローブ
EP2414542B1 (en) 2009-03-30 2017-08-30 Tel HaShomer Medical Research Infrastructure and Services Ltd. Methods of predicting clinical course and treating multiple sclerosis
CN102448484A (zh) 2009-04-01 2012-05-09 医学研究，基础设施和卫生服务基金的特拉维夫医疗中心 调节角质化细胞增生和分化的方法
WO2010116375A1 (en) 2009-04-08 2010-10-14 Yeda Research And Development Co. Ltd. Isolated peptides for regulating apoptosis
AU2010239131A1 (en) 2009-04-21 2011-11-17 Genetic Technologies Limited Methods for obtaining fetal genetic material
GB0908770D0 (en) 2009-04-24 2009-07-01 Danisco Method
US8598322B2 (en) 2009-04-30 2013-12-03 Tel Hashomer Medical Research Infrastucture and Services Ltd. Anti CEACAM1 antibodies and methods of using same
CA2760569C (en) 2009-05-01 2018-01-02 Dako Denmark A/S New antibody cocktail
ES2527455T3 (es) 2009-05-14 2015-01-23 The Chancellor, Masters And Scholars Of The University Of Oxford Diagnóstico clínico de fibrosis/cirrosis hepática usando biomarcadores de proteínas plasmáticas humanas poco abundantes
EP2432876A1 (en) 2009-05-19 2012-03-28 Danisco A/S Use
US9182403B2 (en) 2009-05-19 2015-11-10 Zetiq Technologies Ltd. Kits for and methods of differential staining of cervical cancer cells and/or tissues
US20120128673A1 (en) 2009-05-20 2012-05-24 Schering Corporation Modulation of pilr receptors to treat microbial infections
WO2010137013A1 (en) 2009-05-27 2010-12-02 Ramot At Tel Aviv University Ltd. Crystallized photosystem i units from the pea plant and their use in solid state devices
US20120078163A1 (en) 2009-05-27 2012-03-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of generating connective tissue
EP2435072A2 (en) 2009-05-27 2012-04-04 Yeda Research and Development Co. Ltd. Proteasome inhibitors and uses thereof
WO2010137020A1 (en) 2009-05-28 2010-12-02 Yeda Research And Development Co. Ltd. Methods of treating inflammation
JP5828837B2 (ja) 2009-06-02 2015-12-09 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム 神経変性疾患を有する被験者において抗体により認識される小分子の同定
EP3238534B1 (en) 2009-06-10 2019-11-13 Evogene Ltd. Isolated polynucleotides and polypeptides, and methods of using same for increasing nitrogen use efficiency, yield, growth rate, vigor, biomass, oil content, and/or abiotic stress tolerance
CA2765779A1 (en) 2009-06-24 2010-12-29 Fund For Medical Research Development Of Infrastructure And Health Servi Ces - At Rambam Medical Center Methods and kits for isolating placental derived microparticles and use of same for diagnosis of fetal disorders
NZ597118A (en) 2009-06-25 2013-10-25 Dupont Nutrition Biosci Aps A method for increased expression of a variant lipolytic enzyme
US8283333B2 (en) 2009-07-01 2012-10-09 Protiva Biotherapeutics, Inc. Lipid formulations for nucleic acid delivery
US9663778B2 (en) 2009-07-09 2017-05-30 OPKO Biologies Ltd. Long-acting coagulation factors and methods of producing same
US12203113B2 (en) 2009-07-09 2025-01-21 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
WO2011004379A1 (en) 2009-07-10 2011-01-13 Tel Hashomer Medical Research Infrastructure And Services Ltd. Compositions and methods for treating cancer
EP3406717B1 (en) 2009-07-17 2019-12-11 Bioatla LLC Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts
US8716464B2 (en) 2009-07-20 2014-05-06 Thomas W. Geisbert Compositions and methods for silencing Ebola virus gene expression
WO2011010309A1 (en) 2009-07-21 2011-01-27 Tel Hashomer Medical Research Infrastructure And Services Ltd. A method of diagnosing cancer
GB0913442D0 (en) 2009-07-31 2009-09-16 Univ Ramot Cell-targeting nanoparticles comprising polynucleotide agents and uses thereof
CA2769406A1 (en) 2009-08-04 2011-02-10 Biosystems International Sas Lung cancer biomarkers
WO2011021194A2 (en) 2009-08-17 2011-02-24 Technion Research & Development Foundation Ltd. Pericyte progenitor cells and methods of generating and using same
AU2010286111A1 (en) 2009-08-21 2012-02-16 Beeologics Inc. Preventing and curing beneficial insect diseases via plant transcribed molecules
SG2014004816A (en) 2009-08-21 2014-03-28 Gilead Biologics Inc Catalytic domains from lysyl oxidase and loxl2
EP2816038B8 (en) 2009-08-24 2019-12-25 Lumiphore, Inc. Hopo chelators
EP2470164B1 (en) 2009-08-27 2017-05-31 Technion Research & Development Foundation Ltd. Liposomal compositions and uses of same
IN2015DN02826A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2009-09-03 2015-09-11 Merck Sharp & Dohme
WO2011027966A2 (en) 2009-09-03 2011-03-10 Seegene, Inc. Td probe and its uses
WO2011030336A1 (en) 2009-09-08 2011-03-17 Ramot At Tel-Aviv University Ltd. Methods of diagnosing amyotrophic lateral sclerosis (als)
US9610331B2 (en) 2009-09-08 2017-04-04 Yeda Research And Development Co. Ltd. Methods for hematopoietic precursor mobilization
US20120171213A1 (en) 2009-09-10 2012-07-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of treating tumors
JP2013505022A (ja) 2009-09-16 2013-02-14 バクサート インコーポレーティッド Ｈ１ｎ１感染を予防するための免疫戦略の方法
US8735124B2 (en) 2009-09-17 2014-05-27 Yeda Research And Development Co. Ltd. Isolated PON1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
JP2013505230A (ja) 2009-09-17 2013-02-14 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド 酸化ストレス関連障害を処置するためのペプチド
WO2011033506A2 (en) 2009-09-17 2011-03-24 Yeda Research And Development Co. Ltd. Isolated pon1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
CA2775092A1 (en) 2009-09-23 2011-03-31 Protiva Biotherapeutics, Inc. Compositions and methods for silencing genes expressed in cancer
US20130023433A1 (en) 2009-09-28 2013-01-24 Yuling Luo Methods of detecting nucleic acid sequences with high specificity
US20110077477A1 (en) 2009-09-30 2011-03-31 Glumetrics, Inc. Sensors with thromboresistant coating
US20110081706A1 (en) * 2009-10-02 2011-04-07 TransAlgae Ltd Method and system for efficient harvesting of microalgae and cyanobacteria
CA2777053A1 (en) 2009-10-06 2011-04-14 The Board Of Trustees Of The University Of Illinois Human single-chain t cell receptors
ES2989929T3 (es) 2009-10-11 2024-11-28 Biogen Ma Inc Ensayos relacionados con anti-VLA-4
EP2488646B1 (en) 2009-10-14 2017-12-06 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Compositions for controlling varroa mites in bees
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
US9109206B2 (en) 2009-10-16 2015-08-18 Rutgers, The State University Of New Jersey Method for treating chronic nerve tissue injury using a cell therapy strategy
WO2011048600A1 (en) 2009-10-21 2011-04-28 Danziger Innovations Ltd. Generating genotypic variations in plant genomes by gamete infection
AU2010315400B2 (en) 2009-10-27 2016-07-21 Caris Mpi, Inc. Molecular profiling for personalized medicine
US8467843B2 (en) 2009-11-04 2013-06-18 Glumetrics, Inc. Optical sensor configuration for ratiometric correction of blood glucose measurement
KR20110050327A (ko) 2009-11-07 2011-05-13 주식회사 씨젠 Ｔｈｄ 프라이머 타겟 검출
IL201999A (en) 2009-11-08 2017-10-31 Medical Res & Development Fund For Health Services Bnai Zion Medical Center The State Of Israel A knockout mouse of the 1 – mo gene, a gene associated with morbidly extreme obesity
EP2498806B1 (en) 2009-11-12 2014-12-31 Ramot at Tel-Aviv University Ltd. Compositions comprising pedf and uses of same in the treatment and prevention of ovary-related syndromes
WO2011058555A1 (en) 2009-11-12 2011-05-19 Yeda Research And Development Co. Ltd. A method of editing dna in a cell and constructs capable of same
DK2499236T3 (da) 2009-11-12 2020-03-23 Technion Res & Dev Foundation Dyrkningsmedier, cellekulturer og metoder til dyrkning af pluripotente stamceller i en udifferentieret tilstand
US8592151B2 (en) * 2009-11-17 2013-11-26 Musc Foundation For Research Development Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids
GB0920089D0 (en) 2009-11-17 2009-12-30 Danisco Method
WO2011061736A1 (en) 2009-11-17 2011-05-26 Protalix Ltd. Alkaline alpha galactosidase for the treatment of fabry disease
EP2501800A4 (en) 2009-11-17 2013-05-22 Musc Found For Res Dev HUMAN MONOCLONAL ANTIBODIES AGAINST HUMAN NUCLEOLIN
US9910040B2 (en) 2012-07-09 2018-03-06 Sevident, Inc. Molecular nets comprising capture agents and linking agents
EP2504472A1 (en) 2009-11-24 2012-10-03 Collplant Ltd. Method of generating collagen fibers
US9733242B2 (en) 2012-10-07 2017-08-15 Sevident, Inc. Devices for capturing analyte
MX2012006246A (es) 2009-11-30 2012-06-19 Pluristem Ltd Celulas adherentes de placenta y su uso en el tratamiento de enfermedades.
US8835120B2 (en) 2009-12-02 2014-09-16 Abbott Laboratories Assay for cardiac troponin-T (cTnT)
US8652788B2 (en) * 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
US20110136141A1 (en) * 2009-12-03 2011-06-09 Abbott Laboratories Peptide reagents and method for inhibiting autoantibody antigen binding
US8183002B2 (en) 2009-12-03 2012-05-22 Abbott Laboratories Autoantibody enhanced immunoassays and kits
WO2011067745A2 (en) 2009-12-06 2011-06-09 Rosetta Green Ltd. Compositions and methods for enhancing plants resistance to abiotic stress
WO2011072091A1 (en) 2009-12-09 2011-06-16 Quark Pharmaceuticals, Inc. Methods and compositions for treating diseases, disorders or injury of the cns
WO2011084357A1 (en) 2009-12-17 2011-07-14 Schering Corporation Modulation of pilr to treat immune disorders
CA2784344C (en) 2009-12-21 2018-01-02 Seegene, Inc. Tsg primer target detection
GB0922377D0 (en) 2009-12-22 2010-02-03 Arab Gulf University The Mutant LDL receptor
WO2011087707A1 (en) 2009-12-22 2011-07-21 Elitech Holding B.V. Hypertheromostable endonuclease iv substrate probe
MX381519B (es) 2009-12-28 2025-03-12 Evogene Ltd Polinucleótidos y polipéptidos aislados y métodos para utilizarlos para aumentar el rendimiento de la planta, biomasa, tasa de crecimiento, vigor, contenido de aceite, tolerancia al estrés abiótico y eficacia en el uso de nitrógeno.
CN102781449A (zh) 2009-12-29 2012-11-14 加米达细胞有限公司 增强自然杀伤细胞增殖和活性的方法
WO2011083464A2 (en) 2010-01-05 2011-07-14 Vascular Biogenics Ltd. Methods for use of a specific anti-angiogenic adenoviral agent
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
CN102906278A (zh) 2010-01-11 2013-01-30 比奥根艾迪克Ma公司 用于jc病毒抗体的测定
JP6009357B2 (ja) 2010-01-12 2016-10-19 バスキュラー バイオジェニックス リミテッド アデノウイルスベクターの生産方法およびそれによって生成されるウイルス調製物
WO2011092700A1 (en) 2010-01-27 2011-08-04 Yeda Research And Development Co. Ltd. Antibodies that inhibit metalloproteins
WO2011094669A1 (en) 2010-01-29 2011-08-04 Advanced Cell Diagnostics, Inc. Methods of in situ detection of nucleic acids
CA2786569C (en) 2010-01-29 2019-04-09 Micronics, Inc. Sample-to-answer microfluidic cartridge
US8574832B2 (en) * 2010-02-03 2013-11-05 Massachusetts Institute Of Technology Methods for preparing sequencing libraries
MX2012009088A (es) 2010-02-04 2012-12-05 Gilead Biologics Inc Anticuerpos que se enlazan a lisil oxidasa-tipo2 (loxl2) y metodos de uso para los mismos.
MX2012008884A (es) 2010-02-08 2012-08-31 Agensys Inc Conjugados de anticuerpo y farmaco (adc) que se unen a proteinas 161p2f10b.
WO2011099006A2 (en) 2010-02-11 2011-08-18 Yeda Research And Development Co. Ltd. Enzymatic systems for carbon fixation and methods of generating same
EP2538961B1 (en) 2010-02-24 2016-10-12 Ben Gurion University Of The Negev Research And Development Authority Inhibition of necrosis
WO2011107939A1 (en) 2010-03-01 2011-09-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of predicting efficacy of an anti-vegfa treatment for solid tumors
WO2011107994A1 (en) 2010-03-04 2011-09-09 Yeda Research And Development Co. Ltd. Methods of measuring protein stability
EP2545176B1 (en) 2010-03-08 2016-05-11 Yeda Research and Development Co. Ltd. Recombinant protein production in heterologous systems
ES2809679T3 (es) 2010-03-08 2021-03-05 Monsanto Technology Llc Moléculas polinucleotídicas para la regulación génica en plantas
CN102918159A (zh) 2010-03-11 2013-02-06 雅各布·埃德尔 产生氢的方法
WO2011114251A1 (en) 2010-03-18 2011-09-22 Danisco A/S Foodstuff
WO2011125015A2 (en) 2010-04-05 2011-10-13 Bar-Ilan University Protease-activatable pore-forming polypeptides
US9125931B2 (en) 2010-04-06 2015-09-08 Massachusetts Institute Of Technology Post-transcriptional regulation of RNA-related processes using encoded protein-binding RNA aptamers
KR20130048217A (ko) 2010-04-06 2013-05-09 메사추세츠 인스티튜트 오브 테크놀로지 적은 수의 전사체 측정치를 이용한 유전자 발현 프로파일링
WO2011128895A2 (en) 2010-04-12 2011-10-20 Ben Gurion University Of The Negev Research And Development Authority Sulfotransferase of a red microalga and uses thereof
US8927274B2 (en) 2010-04-12 2015-01-06 Technion Research & Development Foundation Limited Populations of pancreatic progenitor cells and methods of isolating and using same
JP5786020B2 (ja) 2010-04-16 2015-09-30 アボットジャパン株式会社 関節リウマチを診断する方法および試薬
US9518988B2 (en) 2010-04-18 2016-12-13 Yeda Research And Development Co. Ltd. Antibodies and methods of using same for treating ErbB/ErbB ligands associated diseases
EP2563112A4 (en) 2010-04-28 2014-03-05 Evogene Ltd INSULATED POLYNUCLEOTIDES AND POLYPEPTIDES AND METHODS OF USING THE SAME FOR INCREASING PLANT YIELD AND / OR AGRICULTURAL CHARACTERISTICS
WO2011138778A2 (en) 2010-05-04 2011-11-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of identifying inhibitors of polypeptides-of-interest
US9352000B2 (en) 2010-05-05 2016-05-31 Rappaport Family Institute For Research In The Medical Sciences Use of CCL1 in therapy
IL208820A0 (en) 2010-10-19 2011-01-31 Rachel Teitelbaum Biologic female contraceptives
US20120190563A1 (en) 2010-05-07 2012-07-26 Abbott Laboratories Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
EP2567232A1 (en) 2010-05-07 2013-03-13 AbbVie Inc. Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
ES2672918T3 (es) 2010-05-13 2018-06-18 Tel Hashomer Medical Research Infrastructure And Services Ltd. Poblaciones aisladas de células renales adultas y métodos para aislar y usar las mismas
WO2011146479A1 (en) 2010-05-18 2011-11-24 The Texas A&M University System Method and composition for the diagnosis and monitoring of inflammatory diseases
WO2011151833A1 (en) 2010-06-03 2011-12-08 Ramot At Tel-Aviv University Ltd. Methods of treating diabetes and compositions capable of same
CA2801849A1 (en) 2010-06-07 2011-12-15 Osnat Ashur-Fabian Methods and kits for diagnosing conditions related to hypoxia
EP2395354A1 (de) 2010-06-10 2011-12-14 Siemens Healthcare Diagnostics Products GmbH Homogener Aktivitätstest zur Bestimmung von enzymatischen Reaktionen
WO2011158243A2 (en) 2010-06-16 2011-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of diagnosing and treating cancer
WO2011158242A2 (en) 2010-06-16 2011-12-22 Futuragene Israel Ltd. Pest -resistant plants containing a combination of a spider toxin and a chitinase
US8329424B2 (en) 2010-06-25 2012-12-11 Siemens Healthcare Diagnostics Reduction in false results in assay measurements
US20130316338A1 (en) 2010-06-29 2013-11-28 The United States Government As Represented By The Department Of Veterans Affairs CCR6 As A Biomarker of Alzheimer's Disease
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
EP2593468B1 (en) 2010-07-12 2020-06-10 The State of Israel, Ministry of Agriculture and Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center Isolated polynucleotides and methods and plants using same for regulating plant acidity
EP2407242A1 (en) 2010-07-13 2012-01-18 Dublin City University Direct clone analysis and selection technology
WO2012007919A2 (en) 2010-07-15 2012-01-19 Technion Research & Development Foundation Ltd. Nucleic acid construct for increasing abiotic stress tolerance in plants
US20130189284A1 (en) 2010-07-15 2013-07-25 Technion Research & Development Foundation Ltd. Antibodies with t-cell receptor like specificity towards native complexes of mhc class ii and diabetes-associated autoantigenic peptides
WO2012007951A1 (en) 2010-07-15 2012-01-19 Technion Research & Development Foundation Ltd. Isolated high affinity entities with t-cell receptor like specificity towards native complexes of mhc class ii and glutamic acid decarboxylase (gad) autoantigenic peptides
SG187033A1 (en) 2010-07-16 2013-02-28 Bioatla Llc Novel methods of protein evolution
US9677979B2 (en) 2010-07-16 2017-06-13 Vanderbilt University Low resource processor using surface tension valves for extracting, concentrating and detecting molecular species
WO2012011113A2 (en) 2010-07-22 2012-01-26 Shai Yarkoni Regulatory immune cells with enhanced targeted cell death effect
CN103026230B (zh) 2010-07-23 2015-01-14 卢米耐克斯公司 共偶联以控制免疫测定中试剂的反应性
US9120862B2 (en) 2010-07-26 2015-09-01 Abbott Laboratories Antibodies relating to PIVKA-II and uses thereof
US20130130387A1 (en) 2010-07-27 2013-05-23 Technion Research & Development Foundation Limited Method for generating induced pluripotent stem cells from keratinocytes derived from plucked hair follicles
US20130130311A1 (en) 2010-07-27 2013-05-23 Yeda Research And Development Co., Ltd. Methods and systems for assessing clonality of cell cultures
WO2012014205A1 (en) 2010-07-27 2012-02-02 Technion Research & Development Foundation Ltd. Isolated mesenchymal progenitor cells and extracellular matrix produced thereby
WO2012017439A2 (en) 2010-08-04 2012-02-09 Ramot At Tel-Aviv University Ltd. Methods of treating autoimmune diseases of the central nervous system (cns) and neurodegenerative diseases
AU2011285694B2 (en) 2010-08-04 2014-12-18 Idexx Laboratories, Inc. Detection of degradation products of canine NT-proBNP
US10088490B2 (en) 2010-08-20 2018-10-02 Siemens Healthcare Diagnostics Inc. Assay for analytes using multiple receptors
WO2012025914A1 (en) 2010-08-22 2012-03-01 Ramot At Tel-Aviv University Ltd. Induced pluripotent stem cells derived from human pancreatic beta cells
WO2012025925A1 (en) 2010-08-24 2012-03-01 Rappaport Family Institute For Research In The Medical Sciences Methods of improving transplantation using sdf-1alpha
AR082530A1 (es) 2010-08-30 2012-12-12 Evogene Ltd Polinucleotidos y polipeptidos aislados, y metodos para utilizarlos para aumentar la eficacia en el uso de nitrogeno, rendimiento, tasa de crecimiento, vigor, biomasa, contenido de aceite y/o tolerancia al estres abiotico
WO2012032510A1 (en) 2010-09-07 2012-03-15 Yeda Research And Development Co. Ltd. Primers for amplifying dna and methods of selecting same
WO2012032519A2 (en) 2010-09-07 2012-03-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of diagnosing parkinson's disease
EP3572501B1 (en) 2010-09-07 2025-07-16 Technion Research & Development Foundation Limited Novel methods and culture media for culturing pluripotent stem cells
WO2012032520A1 (en) 2010-09-07 2012-03-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Readthrough acetylcholinesterase (ache-r) for treating or preventing parkinson's disease
MX2013002667A (es) 2010-09-08 2013-08-01 Yeda Res & Dev Una combinacion de farmacos inmunosupresores para un injerto estable y a largo plazo.
HUE031063T2 (en) 2010-09-08 2017-06-28 Yeda Res & Dev Anti-third party use of central memory T cells for leukemia / anti-lymphoma treatment
WO2012035539A1 (en) 2010-09-15 2012-03-22 Ramot At Tel-Aviv University Ltd. Methods of expanding and redifferentiating islet beta cells
EP2619321B1 (en) 2010-09-20 2018-08-01 Advanced Cell Diagnostics, Inc. Biomarkers for differentiating melanoma from benign nevus in the skin
WO2012038956A1 (en) 2010-09-20 2012-03-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of treating neurodegenerative diseases
JP5986572B2 (ja) 2010-09-24 2016-09-06 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 固定化プライマーを使用した標的ｄｎａの直接的な捕捉、増幅、および配列決定
KR102353283B1 (ko) 2010-09-29 2022-01-19 어젠시스 인코포레이티드 191p4d12 단백질에 결합하는 항체 약물 컨쥬게이트(ａｄｃ)
CA2813646A1 (en) 2010-10-04 2012-04-12 Robert Zimmer Multivalent synthetic compounds as antibiotic treatment
EP2441520A1 (en) 2010-10-12 2012-04-18 Eppendorf AG Real-time amplification and micro-array based detection of nucleic acid targets in a flow chip assay
WO2012052872A2 (en) 2010-10-17 2012-04-26 Yeda Research And Development Co. Ltd. Methods and compositions for the treatment of insulin-associated medical conditions
WO2012052878A1 (en) 2010-10-19 2012-04-26 Vascular Biogenics Ltd. Isolated polynucleotides and nucleic acid constructs for directing expression of a gene-of-interest in cells
US8658361B2 (en) 2010-10-21 2014-02-25 Advanced Cell Diagnostics, Inc. Ultra sensitive method for in situ detection of nucleic acids
KR20120042100A (ko) 2010-10-22 2012-05-03 주식회사 씨젠 이중표지 고정화 프로브를 이용한 고상에서의 타겟 핵산서열 검출
WO2012056452A2 (en) 2010-10-27 2012-05-03 Nanocyte (Israel) Ltd. Pharmaceutical compositions and delivery devices comprising stinging cells or capsules
ES2688457T3 (es) 2010-10-28 2018-11-02 Yeda Research And Development Co. Ltd. Métodos de generación de anticuerpos contra metaloenzimas
CN103237895A (zh) 2010-11-03 2013-08-07 耶路撒冷希伯来大学伊森姆研究发展有限公司 具有提高的糖化产率的转基因植物以及产生其的方法
US9410132B2 (en) 2010-11-04 2016-08-09 Ben-Gurion University Of The Negev Research And Development Authority Acyl-CoA: diacylglycerol acyltransferase 1-like gene (PtDGAT1) and uses thereof
BR112013012033A2 (pt) 2010-11-15 2016-08-09 Merz Pharma Gmbh & Co Kgaa análogos de dipeptídeos para o tratamento de condições associadas com a formação de fibrila amiloide
US10117895B2 (en) 2010-11-17 2018-11-06 Ben-Gurion University Of The Negev Research And Development Authority T-cell therapy to neurodegenerative diseases
EP2646543A4 (en) 2010-12-02 2014-09-03 Technion Res & Dev Foundation METHOD OF GENERATING CORNEAL CELLS AND CELL POPULATIONS THEREWITH
EP2463382A1 (en) 2010-12-07 2012-06-13 Enterologics, Inc. Method for identifying E. Coli M-17
CA2816495C (en) 2010-12-15 2020-10-13 Kadimastem Ltd. Insulin producing cells derived from pluripotent stem cells
BR122021002243B1 (pt) 2010-12-22 2021-11-09 Evogene Ltd. Método para aumentar a tolerância ao estresse abiótico de uma planta
AR084358A1 (es) 2010-12-27 2013-05-08 Lilly Co Eli Composiciones y metodos para identificar y diferenciar componentes virales de vacunas multivalentes de la “fiebre de embarque” (complejo de enfermedad respiratoria bovina (brdc))
US10226499B2 (en) 2010-12-28 2019-03-12 Kamedis Ltd. Plant extracts for the treatment and prevention of infections
EP2471945A1 (de) 2010-12-30 2012-07-04 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Bestimmung von Inhibitoren der Gerinnung
CA2822969C (en) 2010-12-31 2018-03-13 Jay M. Short Comprehensive monoclonal antibody generation
MX340258B (es) 2011-01-11 2016-07-01 Seegene Inc Detección de secuencias de ácido nucleico objetivo mediante ensayo de escisión y extensión del pto.
ES2632768T3 (es) 2011-01-17 2017-09-15 Life Technologies Corporation Flujo de trabajo para la detección de ligandos empleando ácidos nucleicos
PL3272861T3 (pl) 2011-01-20 2020-07-13 Protalix Ltd. Kompozycje alfa- galaktozydazy
DK2668290T3 (en) 2011-01-28 2017-09-18 Advanced Cell Diagnostics Inc RNASCOPE® HPV ASSAY FOR DETERMINING HPV STATUS OF CANCER AND HEALTH CANCER AND LESSIONS
US20130316358A1 (en) 2011-01-31 2013-11-28 Yeda Research And Development Co. Ltd. Methods of diagnosing disease using overlap extension pcr
WO2012109133A1 (en) 2011-02-07 2012-08-16 Research Development Foundation Engineered immunoglobulin fc polypeptides
WO2012116073A2 (en) 2011-02-23 2012-08-30 The Board Of Trustees Of The University Of Illinois Amphiphilic dendron-coils, micelles thereof and uses
US20130330349A1 (en) 2011-02-23 2013-12-12 Rappaport Family Institute For Research In The Medical Sciences High affinity molecules capable of binding a type a plexin receptor and uses of same
RU2640246C2 (ru) 2011-03-02 2017-12-27 Футураджен Израиль Лтд. Устойчивые к бактериям трансгенные растения
US9365828B2 (en) 2011-03-03 2016-06-14 Ramot At Tel-Aviv University Ltd. Genetically modified muscle cells which express neurotrophic factors
EA032513B1 (ru) 2011-03-06 2019-06-28 Мерк Сероно С.А. Клеточные линии с низким содержанием фукозы и их применение
WO2012120518A1 (en) 2011-03-08 2012-09-13 Ramot At Tel-Aviv University Ltd. Compositions and methods for diagnosing and treating phenylketonuria (pku)
CA2829300A1 (en) 2011-03-08 2012-09-13 King Abdullah University Of Science And Technology Molecular biomarker set for early detection of ovarian cancer
WO2012125582A1 (en) 2011-03-11 2012-09-20 Board Of Regents Of The University Of Nebraska Biomarker for coronary artery disease
CN103533934B (zh) 2011-03-17 2016-03-30 特尔汗什莫尔医学基础设施研究和服务公司 用于治疗自身免疫性疾病的喹诺酮类似物
KR20140019385A (ko) 2011-03-17 2014-02-14 라모트 앳 텔-아비브 유니버시티 리미티드 이중특이성 및 단일특이성, 비대칭성 항체 및 이의 제조방법
KR101835917B1 (ko) 2011-03-22 2018-03-07 플루리스템 리미티드 방사선 또는 화학적 손상을 치료하는 방법들
WO2012129547A1 (en) 2011-03-23 2012-09-27 Elitech Holding B.V. Functionalized 3-alkynyl pyrazolopyrimidine analogues as universal bases and methods of use
US8969003B2 (en) 2011-03-23 2015-03-03 Elitech Holding B.V. Functionalized 3-alkynyl pyrazolopyrimidine analogues as universal bases and methods of use
US20140045764A1 (en) 2011-03-24 2014-02-13 Neurim Pharmaceuticals (1991) Ltd. Neuroprotective peptides
WO2012131680A2 (en) 2011-03-28 2012-10-04 Yeda Research And Development Co. Ltd. Compositions and methods for treating inflammation
WO2012131594A1 (en) 2011-03-28 2012-10-04 Novartis Ag Markers associated with cyclin-dependent kinase inhibitors
EP2691543B1 (en) 2011-03-29 2017-11-01 Seegene, Inc. Detection of target nucleic acid sequence by pto cleavage and extension-dependent cleavage
AU2012236219B2 (en) 2011-04-01 2017-02-23 Immunogen, Inc. Methods for increasing efficacy of FOLR1 cancer therapy
WO2012137202A1 (en) 2011-04-05 2012-10-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Composition comprising an iron indicator attached to a microparticle and uses of same for quantifying non-transferrin bound iron (ntbi) and cellular labile iron (lci)
WO2012138941A1 (en) 2011-04-05 2012-10-11 Longevity Biotech, Inc. Compositions comprising glucagon analogs and methods of making and using the same
JP5990254B2 (ja) 2011-04-06 2016-09-07 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッドＲａｍｏｔ Ａｔ Ｔｅｌ Ａｖｉｖ Ｕｎｉｖｅｒｓｉｔｙ Ｌｔｄ． 代謝活性プロフィルのモニタリング方法および分析方法ならびにそれらの診断使用および治療使用
MX2013011617A (es) 2011-04-08 2013-11-21 Danisco Us Inc Composiciones.
WO2012142164A1 (en) 2011-04-12 2012-10-18 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
SG10201601537QA (en) 2011-04-15 2016-04-28 Pluristem Ltd Methods and systems for harvesting cells
WO2012145270A2 (en) 2011-04-20 2012-10-26 Access Medical Systems, Ltd. Luminescent polymer cyclic amplification
WO2012150598A2 (en) 2011-05-03 2012-11-08 Evogene Ltd. Isolated polynucleotides and polypeptides and methods of using same for increasing plant yield, biomass, growth rate, vigor, oil content, abiotic stress tolerance of plants and nitrogen use efficiency
US9192670B2 (en) 2011-05-04 2015-11-24 Ramot At Tel-Aviv University Ltd. Regulation of amyloid beta molecular composition for the treatment of alzheimer's disease
MX342067B (es) 2011-05-04 2016-09-09 Seegene Inc Detección de secuencias de ácido nucleico objetivo por desdoblamiento e hibridización de oligonucleótido de sonda.
WO2012153333A1 (en) 2011-05-09 2012-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Regeneration and repair of mesenchymal tissue using amelogenin
EP2707507B1 (en) 2011-05-09 2017-11-01 Fluidigm Corporation Probe based nucleic acid detection
WO2012153336A2 (en) 2011-05-12 2012-11-15 Rakuto Bio Technologies Ltd. Methods and device for lightening skin complexion
WO2012156976A1 (en) 2011-05-16 2012-11-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of producing artemisinin in non-host plants and vectors for use in same
CN103620409B (zh) 2011-05-20 2017-04-12 阿波特日本有限公司 用于减少非特异性结合的免疫检验方法和试剂
US9506051B2 (en) 2011-05-20 2016-11-29 Oligomerix, Inc. Tau protease compositions and methods of use
WO2012160526A2 (en) 2011-05-23 2012-11-29 Ofir Menashe Formulations of microorganism comprising particles and uses of same
CA2836503C (en) 2011-05-23 2020-09-22 Yeda Research And Development Co. Ltd. Use of akt phosphorylation as a biomarker for prognosing neurodegenerative diseases and treating same
ES2570591T3 (es) 2011-05-24 2016-05-19 Elitechgroup B V Detección de Staphylococcus aureus resistente a meticilina
US9284351B2 (en) 2011-05-31 2016-03-15 Hutchison Biofilm Medical Solutions Ltd. Dispersion and detachment of cell aggregates
CA2856798A1 (en) 2011-05-31 2012-12-06 Idexx Laboratories, Inc. Detection of degradation products of feline nt-probnp
EP4187248A1 (en) 2011-05-31 2023-05-31 Biogen MA Inc. Method of assessing risk of pml
WO2012164565A1 (en) 2011-06-01 2012-12-06 Yeda Research And Development Co. Ltd. Compositions and methods for downregulating prokaryotic genes
US10166295B2 (en) 2011-06-02 2019-01-01 Opko Biologics Ltd. Pegylated OXM variants
WO2012172555A1 (en) 2011-06-14 2012-12-20 Yeda Research And Development Co. Ltd. Combination therapy to prevent dcis formation and progression to breast cancer
CN103906428A (zh) 2011-06-23 2014-07-02 凯伊玛生物农业科技有限公司 具有部分或完全倍增基因组的普通小麦、植物或其部分，其杂种和产品，以及其生成和使用方法
WO2013010170A1 (en) 2011-07-14 2013-01-17 Lovell Mark A Process for detection of alzheimer's disease from a serum sample
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
CA2842321C (en) 2011-07-18 2022-05-03 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
PH12014500175A1 (en) 2011-07-20 2014-03-03 Kaiima Bio Agritech Ltd Maize plants having a partially or fully multiplied genome and uses thereof
US20130030452A1 (en) 2011-07-27 2013-01-31 Health Corporation - Rambam Devices for surgical applications
HUE044154T2 (hu) 2011-08-04 2019-09-30 Yeda Res & Dev MIR-15 mikro-RNS, valamint az ezt tartalmazó készítmények kortikotropin-felszabadító hormonhoz kapcsolódó orvosi állapotok kezelésére
US8663637B2 (en) 2011-08-05 2014-03-04 Research Development Foundation Methods and compositions for modulation of Olfml3 mediated angiogenesis
WO2013021389A2 (en) 2011-08-09 2013-02-14 Yeda Research And Development Co.Ltd. Downregulation of mir-7 for promotion of beta cell differentiation and insulin production
WO2013025532A2 (en) 2011-08-12 2013-02-21 Siemens Healthcare Diagnostics Inc. Detection of sex steroids
AU2012296138A1 (en) 2011-08-14 2014-03-06 Kaiima Bio Agritech Ltd. Durum wheat plants having a partially or fully multiplied genome and uses thereof
BR112014003315A2 (pt) 2011-08-15 2017-03-01 Univ Chicago composições e métodos relacionados a anticorpos para a proteína a estafilocócica
EP3348575A1 (en) 2011-08-16 2018-07-18 Emory University Jaml specific binding agents, antibodies, and uses related thereto
US9959392B2 (en) 2011-09-07 2018-05-01 Yeda Research And Development Co. Ltd. Olfactory signature and odorant mixture having the same
EP2753716B1 (en) 2011-09-08 2017-11-01 Yeda Research and Development Co. Ltd. Novel risk biomarkers for lung cancer
CN103930130B (zh) 2011-09-08 2016-07-06 耶达研究及发展有限公司 抗第三方中央型记忆t细胞、其产生方法以及其在移植和疾病治疗中的应用
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
CN103974967A (zh) 2011-09-13 2014-08-06 孟山都技术公司 用于杂草控制的方法和组合物
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
WO2013040033A1 (en) 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and compositions for weed control
MX342856B (es) 2011-09-13 2016-10-13 Monsanto Technology Llc Metodos y composiciones para el control de malezas.
CN103957696B (zh) 2011-09-13 2019-01-18 孟山都技术公司 用于杂草控制的方法和组合物
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
WO2013054320A1 (en) 2011-10-11 2013-04-18 Tel Hashomer Medical Research Infrastructure And Services Ltd. Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam)
JP6844939B2 (ja) 2011-10-21 2021-03-17 オ−グレックス ライフ サイエンシズ コーポレイション シトルリン化１４−３−３由来の抗原、及び関節リウマチの診断におけるそれの使用
EP2771464B1 (en) 2011-10-27 2018-03-21 Yeda Research and Development Co. Ltd. Methods of treating cancer
SG11201401648RA (en) 2011-11-03 2014-05-29 Quark Pharmaceuticals Inc Methods and compositions for neuroprotection
EP2776565A1 (en) 2011-11-08 2014-09-17 Quark Pharmaceuticals, Inc. Methods and compositions for treating diseases, disorders or injury of the nervous system
WO2013076729A1 (en) 2011-11-23 2013-05-30 Danziger Dan Flower Farm Otomeria plants
US9617331B2 (en) 2011-11-27 2017-04-11 Yeda Research And Development Co. Ltd. Methods of regulating angiogenesis by administering agents which increase apoB-100 polypeptide
US9833482B2 (en) 2011-12-08 2017-12-05 Yeda Research And Development Co. Ltd. Mammalian fetal pulmonary cells and therapeutic use of same
WO2013093921A1 (en) 2011-12-20 2013-06-27 Collplant Ltd. Collagen coated synthetic polymer fibers
CN105833925B (zh) 2011-12-22 2018-11-13 瑞尔比奥技术有限公司 用于分析物测定的序贯侧向流动毛细管装置
BR112014015960A8 (pt) 2011-12-22 2017-07-04 Yeda Res & Dev método para tratamento de um indivíduo em necessidade de um enxerto de célula ou tecido não singênico, método para tratamento de um indivíduo em necessidade de um transplante hematopoiéticas, método para o tratamento de um indivíduo em necessidade de um enxerto de célula ou tecido não singênico, método para tratamento de um indivíduo em necessidade de um transplante de células hematopoiéticas imaturas, e método para indução de tolerância do doador específico em um indivíduo em necessidade de um enxerto de célula ou tecido não congênito
US9035039B2 (en) 2011-12-22 2015-05-19 Protiva Biotherapeutics, Inc. Compositions and methods for silencing SMAD4
AR089461A1 (es) 2011-12-28 2014-08-27 Kaiima Bio Agritech Ltd Una planta de sorghum cultivada que tiene un genoma parcial o totalmente multiplicado y usos de la misma
KR20140108718A (ko) 2011-12-29 2014-09-12 베일러 리서치 인스티튜트 가와사키 질환용 바이오마커
US20150216998A1 (en) 2012-01-01 2015-08-06 Ramot At Tel-Aviv University Ltd. Endo180-targeted particles for selective delivery of therapeutic and diagnostic agents
WO2013106458A2 (en) 2012-01-09 2013-07-18 Micronics, Inc. Microfluidic reactor system
US10139405B2 (en) 2012-01-24 2018-11-27 Cd Diagnostics, Inc. System for detecting infection in synovial fluid
WO2013114363A2 (en) 2012-01-30 2013-08-08 Yeda Research And Development Co.Ltd. Antimicrobial agents
WO2013114371A1 (en) 2012-02-01 2013-08-08 Protalix Ltd. Dry powder formulations of dnase i
US8771964B2 (en) 2012-02-02 2014-07-08 Siemens Healthcare Diagnostics Inc. Compositions and methods for detection of methadone metabolite
WO2013118120A2 (en) 2012-02-06 2013-08-15 Rosetta Green Ltd. Isolated polynucleotides expressing or modulating micrornas or targets of same, transgenic plants comprising same and uses thereof in improving nitrogen use efficiency, abiotic stress tolerance, biomass, vigor or yield of a plant
JP6348848B2 (ja) 2012-02-13 2018-06-27 ガミダ セル リミテッド 間葉系幹細胞の増殖
MY172539A (en) 2012-02-14 2019-11-30 Opko Biologics Ltd Long-acting coagulation factors and methods of producing same
SG11201404892UA (en) 2012-02-17 2014-09-26 Nvs Technologies Inc Polymer scaffolds for assay applications
WO2013121405A1 (en) 2012-02-19 2013-08-22 Protalix Ltd. Oral unit dosage forms and uses of same for the treatment of gaucher disease
EP3401393B1 (en) 2012-02-22 2020-02-19 Exostem Biotec Ltd Micrornas for the generation of astrocytes
JP2015509366A (ja) 2012-02-22 2015-03-30 ブレインステム バイオテック リミテッド 神経幹細胞および運動ニューロンの生成
SG11201405157PA (en) 2012-02-24 2014-10-30 Protiva Biotherapeutics Inc Trialkyl cationic lipids and methods of use thereof
CN107266425B (zh) 2012-02-29 2020-03-03 坎莫森特里克斯公司 作为ccr9拮抗剂的吡唑-1-基苯磺酰胺
WO2013128454A1 (en) 2012-03-01 2013-09-06 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center Male sterile garlic plants, hybrid offspring of same and methods of generating and using same
CA2864523C (en) 2012-03-05 2019-02-05 Seegene, Inc. Detection of nucleotide variation on target nucleic acid sequence by pto cleavage and extension assay
CN104411724B (zh) 2012-03-07 2018-08-31 耶达研究及发展有限公司 抑制静止素巯基氧化酶(qsox1)的组合物及其用途
US9567392B2 (en) 2012-03-20 2017-02-14 Biogen Ma Inc. JCV neutralizing antibodies
US9334308B2 (en) 2012-03-22 2016-05-10 Ramot At Tel-Aviv University Ltd. PLIF multimeric peptides and uses thereof
US20140178869A1 (en) 2012-04-05 2014-06-26 Advanced Cell Diagnostics, Inc. Detection of immunoglobulin light chain restriction by rna in situ hybridization
US9568431B2 (en) 2012-04-16 2017-02-14 Access Medical Systems, Ltd. Luminescent immunoassays for quantitating analytes having a wide concentration range
CN104271749A (zh) 2012-04-18 2015-01-07 雷蒙特亚特特拉维夫大学有限公司 用于递送核酸的脂化的糖胺聚糖颗粒
EP2838552A4 (en) 2012-04-19 2016-05-18 Opko Biolog Ltd OXYNTOMODULIN VARIANTS WITH EXTENDED ACTION AND PROCESSES FOR PRODUCING SAME
US20130280696A1 (en) 2012-04-23 2013-10-24 Elliott Millenson Devices and methods for detecting analyte in bodily fluid
WO2013160895A1 (en) 2012-04-24 2013-10-31 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
NZ702282A (en) 2012-04-26 2016-07-29 Univ Chicago Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease
US10202642B2 (en) 2012-05-02 2019-02-12 Ibis Biosciences, Inc. DNA sequencing
ES2833524T3 (es) 2012-05-02 2021-06-15 Ibis Biosciences Inc Secuenciación de ADN
EP2846819B1 (en) 2012-05-09 2017-05-03 Yeda Research and Development Co. Ltd. Variants of tace pro-domain as tnf-a inhibitor and their medical use
CN108690132B (zh) 2012-05-10 2022-10-14 生物蛋白有限公司 多特异单克隆抗体
US10458915B2 (en) 2012-05-18 2019-10-29 Pacific Biosciences Of California, Inc. Heteroarylcyanine dyes
US8865158B2 (en) 2012-05-22 2014-10-21 Ramot At Tel-Aviv University Ltd. Bacteriophages for reducing toxicity of bacteria
MX369626B (es) 2012-05-24 2019-11-13 Mountgate Group Ltd Composiciones y metodos relacionados con la prevencion y el tratamiento de infecciones por rabia.
WO2013175480A1 (en) 2012-05-24 2013-11-28 A.B. Seeds Ltd. Compositions and methods for silencing gene expression
HUE051020T2 (hu) 2012-06-01 2021-01-28 Icahn School Med Mount Sinai A ceramid szintjei a fertõzések kezelésében és megelõzésében
US9731048B2 (en) 2012-06-03 2017-08-15 Ben-Gurion University Of The Negev Research And Development Authority Functionalized titanium binding peptides and implants coated with same
AU2013273135B2 (en) 2012-06-04 2017-12-07 Opko Biologics Ltd. Pegylated OXM variants
EP2864500B1 (en) 2012-06-22 2018-08-22 HTG Molecular Diagnostics, Inc. Molecular malignancy in melanocytic lesions
EP2867330B1 (en) 2012-06-27 2018-10-10 Siemens Healthcare Diagnostics Inc. Compositions and methods for liquid mixing assessment
WO2014006621A1 (en) 2012-07-03 2014-01-09 Nanospun Technologies Ltd. Methods and devices for adsorption and biodegradation of petroleum
ES2661883T3 (es) 2012-07-09 2018-04-04 Novartis Ag Biomarcadores asociados con inhibidores de CDK
US20150173883A1 (en) 2012-07-18 2015-06-25 President And Fellows Of Harvard College Modification of surfaces for simultaneous repellency and targeted binding of desired moieties
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
WO2014018375A1 (en) 2012-07-23 2014-01-30 Xenon Pharmaceuticals Inc. Cyp8b1 and uses thereof in therapeutic and diagnostic methods
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
SG11201500423TA (en) 2012-07-27 2015-02-27 Univ Illinois Engineering t-cell receptors
DK2880155T3 (da) 2012-07-29 2019-07-15 Yeda Res & Dev Anvendelse af den reduktive glycinvej til generering af formatotrofiske og autotrofiske mikroorganismer
HK1205453A1 (en) 2012-07-31 2015-12-18 Yeda Research And Development Co. Ltd. Methods of diagnosing and treating motor neuron diseases
US9371568B2 (en) 2012-07-31 2016-06-21 Novartis Ag Markers associated with human double minute 2 inhibitors
DK2880151T3 (da) 2012-08-06 2020-08-17 Brainstorm Cell Therapeutics Ltd Fremgangsmåder til frembringelse af mesenkymale stemceller, som udskiller neurotrofiske faktorer
CN111330016B (zh) 2012-08-23 2025-03-25 艾更斯司股份有限公司 结合158p1d7蛋白的抗体药物偶联物(adc)
WO2014035712A1 (en) 2012-08-28 2014-03-06 Pierce Biotechnology, Inc. Benzopyrylium compounds
AR092868A1 (es) 2012-09-03 2015-05-06 A B Seeds Ltd Metodo para mejorar la tolerancia al estres abiotico de plantas y plantas generadas mediante dicho metodo
WO2014041544A1 (en) 2012-09-12 2014-03-20 Ramot At Tel-Aviv University Ltd. Immunoparticles and methods of generating and using same
EP2906954B1 (en) 2012-10-09 2018-04-11 Ramot at Tel-Aviv University Ltd. Methods and kits for predicting prognosis of cancer using soluble mortalin in blood
CA2887933A1 (en) 2012-10-12 2014-04-17 Arizona Board Of Agents, On Behalf Of Arizona State University Antibody based reagents that specifically recognize toxic oligomeric forms of tau
MX2015004620A (es) 2012-10-12 2015-10-22 Nvs Technologies Inc Polimeros que tienen grupos reactivos ortogonales y usos de los mismos.
WO2014072832A2 (en) 2012-10-18 2014-05-15 Oslo Universitetstssykehus Hf Biomarkers for cervical cancer
US20150354006A1 (en) 2012-10-19 2015-12-10 Novartis Ag Markers for acute lymphoblastic leukemia
WO2014063097A1 (en) 2012-10-19 2014-04-24 Danisco Us Inc. Stabilization of biomimetic membranes
US9395369B2 (en) 2012-10-19 2016-07-19 Regents Of The University Of Minnesota Guinea pig cytomegalovirus (CIDMTR strain)
WO2014064682A1 (en) 2012-10-24 2014-05-01 Yeda Research And Development Co. Ltd. Combinations of epidermal growth factor receptor targeting antibodies for treating cancer
AU2013334583B2 (en) 2012-10-24 2018-09-13 Research Development Foundation JAM-C antibodies and methods for treatment of cancer
EP2912181B1 (en) 2012-10-29 2017-11-29 Yeda Research and Development Co., Ltd. Aptamers, multimeric aptamers and uses thereof
KR20150085064A (ko) 2012-11-16 2015-07-22 더 리젠트스 오브 더 유니이버시티 오브 캘리포니아 단백질 화학적 변형을 위한 피크테 스펭글러 결합
KR102341581B1 (ko) 2012-11-20 2021-12-21 옵코 바이오로직스 리미티드 생식샘자극 호르몬 카복시 말단 펩타이드들과 부착하여 폴리펩타이드들의 유체역학적 부피를 증가시키는 방법
WO2014083567A2 (en) 2012-11-29 2014-06-05 Yeda Research And Development Co. Ltd. Methods of preventing tumor metastasis, treating and prognosing cancer and identifying agents which are putative metastasis inhibitors
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
US9121859B2 (en) 2012-12-04 2015-09-01 Siemens Healthcare Diagnostics Inc. Compounds and methods for determination of FKBP-binding immunosuppressant drugs
WO2014100732A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Fluidic circuits and related manufacturing methods
JP2016509206A (ja) 2012-12-21 2016-03-24 マイクロニクス， インコーポレイテッド 携帯型蛍光検出システムおよびマイクロアッセイカートリッジ
KR20150096788A (ko) 2012-12-21 2015-08-25 마이크로닉스 인코포레이티드. 마이크로 유체공학 용도를 위한 저탄성 막
EP2941488B1 (en) 2013-01-01 2023-03-22 Monsanto Technology LLC Methods of introducing dsrna to plant seeds for modulating gene expression
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
WO2014108850A2 (en) 2013-01-09 2014-07-17 Yeda Research And Development Co. Ltd. High throughput transcriptome analysis
WO2014108854A1 (en) 2013-01-09 2014-07-17 Fusimab Ltd. Monospecific anti-hgf and anti-ang2 antibodies and bispecific anti-hgf/anti-ang2 antibodies
EP3431985A1 (en) 2013-01-17 2019-01-23 Novellusdx Ltd. Methods and systems for identifying patient specific driver mutations
EP2945942B1 (en) 2013-01-18 2018-05-09 ARK Diagnostics, Inc. Voriconazole immunoassays
WO2014116721A1 (en) 2013-01-22 2014-07-31 The Arizona Board Of Regents For And On Behalf Of Arizona State University Geminiviral vector for expression of rituximab
US10077475B2 (en) 2013-01-24 2018-09-18 California Institute Of Technology FRET-based analytes detection and related methods and systems
WO2014116884A1 (en) 2013-01-24 2014-07-31 California Institute Of Technology Chromophore-based characterization and detection methods
AU2014212230B2 (en) 2013-02-01 2019-07-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Method for generating retinal pigment epithelium (RPE) cells from induced pluripotent stem cells (iPSCs)
EP3885446A1 (en) 2013-02-01 2021-09-29 The Regents of The University of California Methods for genome assembly and haplotype phasing
US9411930B2 (en) 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
EP2950808B1 (en) 2013-02-04 2019-08-21 Ramot at Tel-Aviv University Ltd. Generation of cytotoxic tumor specific cell lines and uses thereof
WO2014126861A1 (en) 2013-02-13 2014-08-21 Ark Diagnostics, Inc. Posaconazole immunoassays
WO2014130846A1 (en) 2013-02-22 2014-08-28 Seungpyo Hong Transdermal drug delivery using amphiphilic dendron-coil micelles
EP2770065B1 (en) 2013-02-25 2017-12-13 Seegene, Inc. Detection of nucleotide variation on target nucleic acid sequence
WO2014136117A1 (en) 2013-03-06 2014-09-12 Protalix Ltd. USE OF PLANT CELLS EXPRESSING A TNFalpha POLYPEPTIDE INHIBITOR IN THERAPY
WO2014136113A1 (en) 2013-03-06 2014-09-12 Protalix Ltd. Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same
US20140255928A1 (en) 2013-03-11 2014-09-11 Elitech Holding B.V. Methods for true isothermal strand displacement amplification
TWI582239B (zh) 2013-03-11 2017-05-11 諾華公司 與ｗｎｔ抑制劑相關之標記
AU2014248958A1 (en) 2013-03-13 2015-10-01 Monsanto Technology Llc Methods and compositions for weed control
KR20220038550A (ko) 2013-03-13 2022-03-28 메소 스케일 테크놀러지즈, 엘엘시 개선된 분석 방법
CN105074008A (zh) 2013-03-13 2015-11-18 孟山都技术有限公司 用于杂草控制的方法和组合物
US10114015B2 (en) 2013-03-13 2018-10-30 Meso Scale Technologies, Llc. Assay methods
JP2016508733A (ja) 2013-03-13 2016-03-24 シージーン アイエヌシー メルティングピーク分析を利用したターゲット核酸配列の定量
BR112015023069A2 (pt) 2013-03-14 2017-07-18 Nvs Tech Inc superfície de oxidação para o sequestro de biomoléculas e métodos relacionados
WO2014159242A1 (en) 2013-03-14 2014-10-02 Novartis Ag Notch 3 mutants and uses thereof
WO2014159063A1 (en) 2013-03-14 2014-10-02 Elitech Holding B.V. Functionalized 3-alkynyl pyrazolopyrimidine analogues as universal bases and methods of use
WO2014159239A2 (en) 2013-03-14 2014-10-02 Novartis Ag Antibodies against notch 3
US9273349B2 (en) 2013-03-14 2016-03-01 Affymetrix, Inc. Detection of nucleic acids
ES2935257T3 (es) 2013-03-15 2023-03-03 Univ Chicago Métodos y composiciones relacionadas con la actividad de las células T
MX385153B (es) 2013-03-15 2025-03-14 Gladiator Biosciences Inc Dominios gla como agentes terapéuticos.
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
EP2971160B1 (en) 2013-03-15 2018-05-30 Bio-Rad Laboratories, Inc. Digital assays for mutation detection
WO2014145718A2 (en) 2013-03-15 2014-09-18 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
JP6346265B2 (ja) 2013-03-21 2018-06-20 ジェニスフィア・エルエルシー Ｄｎａインターカレーティング剤の細胞送達
KR101403507B1 (ko) 2013-03-21 2014-06-09 주식회사 현일바이오 결핵균 및 비결핵 마이코박테리아의 선택적 검출 방법, 그리고 이를 이용한 키트
CA2907680A1 (en) 2013-03-21 2014-09-25 Collplant Ltd. Compositions comprising collagen and prp for tissue regeneration
BR112015024558A2 (pt) 2013-03-24 2017-07-18 Biokine Therapeutics Ltd método para tratamento de leucemia mieloide.
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
US20140308751A1 (en) 2013-04-12 2014-10-16 Siemens Healthcare Diagnostics Inc. Assays for Analyte Homologs
MX2015014582A (es) 2013-04-21 2016-07-15 Yeda Res & Dev Agentes para regulacion hacia abajo de la actividad y/o cantidad de bcl-xl y/o bcl-w.
ES2831424T3 (es) 2013-04-23 2021-06-08 Yeda Res & Dev Células madre pluripotentes naif aisladas y métodos para generarlas
US9714268B2 (en) 2013-04-25 2017-07-25 Yeda Research And Development Co. Ltd. Use of inhibitory peptides for the treatment of inflammatory diseases
WO2014176047A1 (en) 2013-04-25 2014-10-30 Novartis Ag Markers for ezh2 inhibitors
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
JP6472788B2 (ja) 2013-05-07 2019-02-20 マイクロニクス， インコーポレイテッド 粘土鉱物およびアルカリ性溶液を使用して核酸含有試料を調製するための方法
CN105189784B (zh) 2013-05-07 2020-06-30 珀金埃尔默健康科学有限公司 用于制备和分析核酸的装置
US9328384B2 (en) 2013-05-13 2016-05-03 Elitechgroup B.V. Droplet digital PCR with short minor groove probes
CA2913155A1 (en) 2013-05-21 2014-11-27 President And Fellows Of Harvard College Engineered heme-binding compositions and uses thereof
EP2999717B1 (en) 2013-05-21 2018-08-08 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Treatment of mast cell related pathologies
WO2014191995A2 (en) 2013-05-27 2014-12-04 Rakuto Bio Technologies Ltd. Enzymatic system-containing cosmetic compositions
WO2014193804A1 (en) 2013-05-28 2014-12-04 Biogen Idec Ma Inc. Method of assessing risk of pml
ES2754177T3 (es) 2013-06-12 2020-04-16 Massachusetts Gen Hospital Métodos para la detección multiplexada de moléculas diana y sus usos
SG10201710528WA (en) 2013-06-18 2018-01-30 Dnatrix Inc Treatment of brain cancer with oncolytic adenovirus
WO2014207744A1 (en) 2013-06-24 2014-12-31 Ramot At Tel-Aviv University Ltd. Omentum based scaffold and delivery system
JP6566941B2 (ja) 2013-06-28 2019-08-28 ベイラー リサーチ インスティテュートＢａｙｌｏｒ Ｒｅｓｅａｒｃｈ Ｉｎｓｔｉｔｕｔｅ 多発性硬化症のための樹状細胞ａｓｇｐｒ標的化免疫治療薬
WO2015008985A1 (en) 2013-07-15 2015-01-22 Seegene, Inc. Detection of target nucleic acid sequence by pto cleavage and extension-dependent immobilized oligonucleotide hybridization
EP3608412A3 (en) 2013-07-19 2020-04-08 Monsanto Technology LLC Compositions and methods for controlling leptinotarsa
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
WO2015015489A1 (en) 2013-07-30 2015-02-05 Biolinerx Ltd. Antibody for treating diabetes and autoimmune diseases
RU2679657C2 (ru) 2013-08-01 2019-02-12 Эдженсис, Инк. Конъюгаты антител с лекарственными средствами, связывающиеся с белками cd37
WO2015027120A1 (en) 2013-08-21 2015-02-26 Jiang Jean X Compositions and methods for targeting connexin hemichannels
US9938316B2 (en) 2013-08-29 2018-04-10 Yeda Research And Development Co. Ltd. Selective inhibitors of α2 isoform of Na,K-ATPase and use thereof for reduction of intra-ocular pressure and as cardiotonic agents
KR102585409B1 (ko) 2013-08-30 2023-10-05 이뮤노젠 아이엔씨 엽산 수용체 1의 검출을 위한 항체 및 분석
US20160251410A1 (en) 2013-09-03 2016-09-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions and methods for expressing recombinant polypeptides
IL228284A (en) 2013-09-03 2016-12-29 Technion Res & Dev Foundation Implants from cellular scaffolding and blood vessel stalk
WO2015033344A1 (en) 2013-09-05 2015-03-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods and kits for inhibiting pathogenicity of group a streptococcus (gas) or group g streptococcus (ggs)
WO2015037009A1 (en) 2013-09-16 2015-03-19 Plexicure Ltd. Isolated proteins capable of binding plexin-a4 and methods of producing and using same
ES2717446T3 (es) 2013-09-17 2019-06-21 Yeda Res & Dev Péptidos derivados de ERK y usos de los mismos
CN105960453A (zh) 2013-10-01 2016-09-21 卡迪马干细胞有限公司 从人多能干细胞定向分化星形胶质细胞用于肌萎缩侧索硬化(als)的治疗和药物筛选
EP3052193B1 (en) 2013-10-03 2018-01-31 Oklahoma Medical Research Foundation Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare
US9476884B2 (en) 2013-10-04 2016-10-25 University Of Massachusetts Hybridization- independent labeling of repetitive DNA sequence in human chromosomes
US11447814B2 (en) 2013-10-18 2022-09-20 Seegene, Inc. Detection of target nucleic acid sequence on solid phase by PTO cleavage and extension using HCTO assay
KR102444140B1 (ko) 2013-10-21 2022-09-15 옵코 바이오로직스 리미티드 장시간-작용하는 폴리펩티드, 그의 생산 방법, 및 그의 투여 방법
US20150158926A1 (en) 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
EP3060656A1 (en) 2013-10-24 2016-08-31 Yeda Research and Development Co., Ltd. Polynucleotides encoding brex system polypeptides and methods of using same
WO2015061260A1 (en) 2013-10-24 2015-04-30 Siemens Healthcare Diagnostics Inc. Assays for macromolecular analytes
JP6505681B2 (ja) 2013-10-31 2019-04-24 バイオカイン セラピューティックス リミテッド Ｆｌｔ３変異を有する急性骨髄性白血病を治療するための医薬組成物
PL3066200T3 (pl) 2013-11-04 2025-03-31 Greenlight Biosciences, Inc. Kompozycje i sposoby do zwalczania inwazji pasożytów i szkodników stawonogów
CA2965327C (en) 2013-11-08 2023-05-09 The Board Of Regents Of The University Of Texas System Vh4 antibodies against gray matter neuron and astrocyte
CA2930693A1 (en) 2013-11-15 2015-05-21 The Board Of Trustees Of The Leland Stanford Junior Unversity Methods of treating heart failure with agonists of hypocretin receptor 2
MX2016006584A (es) 2013-11-20 2016-09-06 Univ Iowa Res Found Métodos y composiciones para tratar los depósitos de amiloide.
TR201908404T4 (tr) 2013-11-22 2019-07-22 Hutchinson Fred Cancer Res İşlenmiş yüksek afinite insan t hücresi reseptörleri.
EP3074044A2 (en) 2013-11-28 2016-10-05 Yeda Research and Development Co., Ltd. Synaptojanin-2 inhibitors and uses thereof
EP3074391B1 (en) 2013-11-28 2019-07-31 Tel Hashomer Medical Research Infrastructure And Services Ltd. Rna polymerase i inhibitors and uses thereof
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
ES2697757T3 (es) 2013-12-10 2019-01-28 Yeda Res & Dev Uso de enzimas que catalizan la síntesis de piruvato a partir de formiato y acetil-CoA y bacterias que expresan la misma
WO2015089172A1 (en) 2013-12-13 2015-06-18 Siemens Healthcare Diagnostics Inc. Pretreatment agent in non-agglutination assays
US20150191744A1 (en) 2013-12-17 2015-07-09 University Of Massachusetts Cas9 effector-mediated regulation of transcription, differentiation and gene editing/labeling
WO2015095604A2 (en) 2013-12-18 2015-06-25 President And Fellows Of Harvard College Methods and assays relating to circulating tumor cells
EP3084437B1 (en) 2013-12-18 2018-02-28 Siemens Healthcare Diagnostics Inc. Detection of endothelial disease
CA2934039A1 (en) 2013-12-19 2015-06-25 Danisco Us Inc. Use of hydrophobins to increase gas transferin aerobic fermentation processes
DK3447493T3 (da) 2014-01-07 2020-08-17 Bioatla Llc Proteinrettede ortologer
WO2015106281A1 (en) 2014-01-13 2015-07-16 Baylor Research Institute Novel vaccines against hpv and hpv-related diseases
CN105979770B (zh) 2014-01-15 2019-07-05 孟山都技术公司 用于使用epsps多核苷酸的杂草控制的方法和组合物
CN106132992B (zh) 2014-01-29 2020-08-07 达娜-法勃肿瘤研究所公司 针对muc1-c/胞外结构域(muc1-c/ecd)的抗体
US20160340659A1 (en) 2014-01-30 2016-11-24 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. Actin binding peptides and compositions comprising same for inhibiting angiogenesis and treating medical conditions associated with same
US20170042893A1 (en) 2014-02-03 2017-02-16 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Use of casein kinase i inhibitors for depleting stem cells
CN111733231A (zh) 2014-02-05 2020-10-02 耶达研究及发展有限公司 用于治疗和诊断的微rna和包含所述微rna的组合物
CN106573976B (zh) 2014-02-06 2020-05-05 耶达研究及发展有限公司 抗cd84抗体、包含所述抗体的组合物及其用途
US20150247204A1 (en) 2014-02-07 2015-09-03 The General Hopital Corporation Differential diagnosis of hepatic neoplasms
WO2015118547A1 (en) 2014-02-10 2015-08-13 Protalix Ltd. Method of maintaining disease stability in a subject having gaucher's disease
US10564149B2 (en) 2014-02-11 2020-02-18 Brainstorm Cell Therapeutics Ltd. Populations of mesenchymal stem cells that secrete neurotrophic factors
WO2015123565A1 (en) 2014-02-14 2015-08-20 The General Hospital Corporation Methods for diagnosing igg4-related disease
US9540688B2 (en) 2014-02-19 2017-01-10 Personal Genomics, Inc. Real-time sequencing method for single molecule
US20150247205A1 (en) 2014-02-28 2015-09-03 The General Hospital Corporation Diagnosis of multiple myeloma and lymphoma
EP3114483A1 (en) 2014-03-03 2017-01-11 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Method and device for detection of pseudomonas aeruginosa
EP2923709A1 (en) 2014-03-28 2015-09-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Multi-component-multistage malaria vaccine
WO2015147370A1 (en) 2014-03-28 2015-10-01 Seegene, Inc. Detection of target nucleic acid sequences using different detection temperatures
US11091770B2 (en) 2014-04-01 2021-08-17 Monsanto Technology Llc Compositions and methods for controlling insect pests
WO2015155777A1 (en) 2014-04-10 2015-10-15 Bonus Therapeutics Ltd. Bone repair compositions
FI4026917T3 (fi) 2014-04-14 2024-02-14 Yissum Research And Development Company Of The Hebrew Univ Of Jerusalem Ltd Menetelmä ja välineistö solujen tai kudoksen kuoleman tai DNA:n kudos- tai solualkuperäin määrittämiseksi DNA-metylaatioanalyysin avulla
US10590467B2 (en) 2014-04-17 2020-03-17 Yeda Research And Development Co. Ltd. Methods and kits for analyzing DNA binding moieties attached to DNA
US11427647B2 (en) 2014-04-27 2022-08-30 Famewave Ltd. Polynucleotides encoding humanized antibodies against CEACAM1
MD20160130A2 (ro) 2014-04-27 2017-04-30 Ccam Biotherapeutics Ltd. Anticorpi umanizaţi contra CEACAM1
CN106460048B (zh) 2014-04-28 2021-01-05 耶达研究及发展有限公司 针对试剂的微生物组应答
WO2015170322A2 (en) 2014-05-04 2015-11-12 Forrest Innovations Ltd. Compositions and methods of using same for increasing resistance of infected mosquitoes
EP2942627A1 (en) 2014-05-05 2015-11-11 MicroBPlex, Inc. Media elaborated with newly synthesized antibodies (mensa) from recently proliferated antibody secreting cells (asc) and uses thereof
CA2948043A1 (en) 2014-05-07 2015-11-12 Nplex Pty Ltd Synthetic thread based lateral flow immunoassay
AU2015255883A1 (en) 2014-05-08 2016-10-27 Novodiax, Inc. Direct immunohistochemistry assay
US10301310B2 (en) 2014-05-09 2019-05-28 Biosearch Technologies, Inc. Cosmic quenchers
WO2015175856A1 (en) 2014-05-15 2015-11-19 Meso Scale Technologies, Llc. Improved assay methods
WO2015179435A1 (en) 2014-05-19 2015-11-26 Bayer Healthcare Llc Optimized humanized monoclonal antibodies against activated protein c and uses thereof
WO2015177800A2 (en) 2014-05-22 2015-11-26 Yeda Research And Development Co. Ltd. Recombinant microorganisms capable of carbon fixation
WO2015186129A1 (en) 2014-06-02 2015-12-10 Technion Research & Development Foundation Limited. Compositions and methods of selectively inhibiting irp1 and treating inflammation
US20170095512A1 (en) 2014-06-02 2017-04-06 Kadimastem Ltd. Methods of inducing myelination and maturation of oligodendrocytes
EP2955517A1 (de) 2014-06-10 2015-12-16 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Stabilisierung von Körperflüssigkeitsproben durch die Zugabe von Detergenz
CN106795515B (zh) 2014-06-23 2021-06-08 孟山都技术公司 用于经由rna干扰调控基因表达的组合物和方法
US20170183376A1 (en) 2014-06-24 2017-06-29 Insight Biopharmaceuticals Ltd. Methods of purifying antibodies
SG11201610630RA (en) 2014-06-25 2017-01-27 Tel Hashomer Medical Res Infrastructure & Services Ltd Identification of cancer stem cell markers and use of same for diagnosis and treatment
US11807857B2 (en) 2014-06-25 2023-11-07 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
WO2015198326A1 (en) 2014-06-26 2015-12-30 Ramot At Tel-Aviv University Ltd. Liposomal formulations for delivery of nucleic acids
CN112979818A (zh) 2014-06-27 2021-06-18 西门子医疗保健诊断公司 对维生素d差向异构体特异性的结合配偶体
KR20180021934A (ko) 2014-06-27 2018-03-05 지멘스 헬쓰케어 다이아그노스틱스 인크. 비타민 d 검정에서 비타민 d 에피머에 특이적인 결합 파트너
WO2016005985A2 (en) 2014-07-09 2016-01-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method for reprogramming cells
ES2799404T3 (es) 2014-07-15 2020-12-17 Yissum Research And Development Company Of The Hebrew Univ Of Jerusalem Ltd Polipéptidos de CD44 aislados y usos de los mismos
CA2955414A1 (en) 2014-07-21 2016-01-28 Novellusdx Ltd. Methods and systems for determining oncogenic index of patient specific mutations
CN106715719B (zh) 2014-07-21 2022-08-02 福尔生物治疗有限公司 用于确定患者特定突变的药物反应的方法
CN106604993A (zh) 2014-07-29 2017-04-26 孟山都技术公司 用于控制昆虫害虫的组合物和方法
JP2017525351A (ja) 2014-07-30 2017-09-07 イェダ リサーチ アンド ディベロップメント カンパニー リミテッドＹｅｄａ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏ．Ｌｔｄ． 多能性幹細胞の培養用培地
WO2016019360A1 (en) 2014-08-01 2016-02-04 Dovetail Genomics Llc Tagging nucleic acids for sequence assembly
RU2730836C2 (ru) 2014-08-14 2020-08-26 Мемед Диагностикс Лтд. Вычислительный анализ биологических данных с применением многообразия и гиперплоскости
WO2016030899A1 (en) 2014-08-28 2016-03-03 Yeda Research And Development Co. Ltd. Methods of treating amyotrophic lateral scleroses
US10526416B2 (en) 2014-09-08 2020-01-07 Yeda Research And Development Co. Ltd. Anti-HER3 antibodies and uses of same
JP2017534574A (ja) 2014-09-08 2017-11-24 イェダ リサーチ アンド ディベロップメント カンパニー リミテッドＹｅｄａ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏ．Ｌｔｄ． チロシンキナーゼ阻害薬（ｔｋｉ）に耐性のがんを処置するための組成物および方法
EP2992895A1 (en) 2014-09-08 2016-03-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Three-component-multistage malaria vaccine
IL287789B2 (en) 2014-09-11 2024-05-01 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo Mogroside compounds, methods for their preparation, preparations including them and their uses
WO2016038550A1 (en) 2014-09-11 2016-03-17 Novartis Ag Inhibition of prmt5 to treat mtap-deficiency-related diseases
IL234638A0 (en) 2014-09-14 2014-12-02 Yeda Res & Dev NMDA receptor antagonists for the treatment of Gaucher disease
ES2804826T3 (es) 2014-09-16 2021-02-09 Synermore Biologics Co Ltd Anticuerpo anti-EGFR y usos del mismo
US10174320B2 (en) 2014-09-21 2019-01-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Downregulating miR-132 for the treatment of lipid related disorders
KR102514565B1 (ko) 2014-10-06 2023-03-24 케모센트릭스, 인크. C-c 케모카인 수용체 타입 9 (ccr9)의 억제제 및 항-알파4베타7 인테그린 차단 항체의 조합 요법
WO2016061111A1 (en) 2014-10-13 2016-04-21 Life Technologies Corporation Methods, kits & compositions for determining gene copy numbers
GB2555995B (en) 2014-10-20 2019-06-26 Gen Probe Inc Red blood cell lysis solution
US20170306360A1 (en) 2014-10-24 2017-10-26 Danisco Us Inc. Method for producing alcohol by use of a tripeptidyl peptidase
DK3209774T3 (da) 2014-10-24 2020-05-25 Dupont Nutrition Biosci Aps Anvendelse af prolintolerante tripeptidylpeptidaser i foderadditivsammensætninger
AU2015346969B2 (en) 2014-11-13 2019-03-21 Enzootic Holdings Ltd. Functional sex-reversal of decapod crustacean females
CA2967233A1 (en) 2014-11-17 2016-05-26 Yeda Research And Development Co. Ltd. Method of analyzing microbiome
US20180042994A1 (en) 2014-11-17 2018-02-15 Yeda Research And Development Co. Ltd. Methods of treating diseases related to mitochondrial function
RU2758608C2 (ru) 2014-11-19 2021-11-01 Конинклейке Филипс Н.В. Способ диагностики с использованием hnl
WO2016079739A2 (en) 2014-11-20 2016-05-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions and methods for producing polypeptides with a modified glycosylation pattern in plant cells
CN107208070B (zh) 2014-11-26 2021-09-07 技术创新动力基金（以色列）有限合伙公司 细菌基因的靶向消除
KR20170081268A (ko) 2014-11-27 2017-07-11 단지거 이노베이션즈 엘티디. 게놈 편집용 핵산 구조체
US11279974B2 (en) 2014-12-01 2022-03-22 The Broad Institute, Inc. Method for in situ determination of nucleic acid proximity
US10479997B2 (en) 2014-12-01 2019-11-19 Novartis Ag Compositions and methods for diagnosis and treatment of prostate cancer
AU2015360694B2 (en) 2014-12-08 2021-10-14 Berg Llc Use of markers including filamin a in the diagnosis and treatment of prostate cancer
CN111624345A (zh) 2014-12-11 2020-09-04 米密德诊断学有限公司 用于诊断多种感染的标记组合及其使用方法
US10688330B2 (en) 2014-12-11 2020-06-23 Yeda Research And Development Co. Ltd. Isolated phosphotriesterase polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
WO2016094607A2 (en) 2014-12-12 2016-06-16 Elitechgroup B.V. Methods and compositions for detecting antibiotic resistant bacteria
US10266903B2 (en) 2014-12-12 2019-04-23 Elitechgroup, Inc. Methods and compositions for detecting antibiotic resistant bacteria
AU2015370664B2 (en) 2014-12-23 2018-08-23 Cj Bioscience, Inc. Immune modulation
WO2016103269A1 (en) 2014-12-23 2016-06-30 Ramot At Tel-Aviv University Ltd. Populations of neural progenitor cells and methods of producing and using same
JP6427278B2 (ja) 2014-12-23 2018-11-21 フォーディー ファーマ リサーチ リミテッド４Ｄ Ｐｈａｒｍａ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ ｐｉｒｉｎポリペプチド及び免疫モジュレーション
MX2017008818A (es) 2014-12-30 2018-03-14 Cell Cure Neurosciences Ltd Metodos para tratar enfermedades de la retina.
BR112017014345A2 (pt) 2014-12-30 2018-01-02 Cell Cure Neurosciences Ltd. populações de células do rpe e métodos de gerar as mesmas
WO2016108240A1 (en) 2014-12-30 2016-07-07 Cell Cure Neurosciences Ltd. Assessing retinal pigment epithelial cell populations
CA2970216A1 (en) 2015-01-04 2016-07-07 Protalix Ltd. Modified dnase and uses thereof
WO2016116935A1 (en) 2015-01-21 2016-07-28 Yeda Research And Development Co. Ltd. Use of rasa2 as a prognostic and therapeutic marker for melanoma
EP3256589B1 (en) 2015-01-22 2021-12-22 Monsanto Technology LLC Compositions and methods for controlling leptinotarsa
US10457737B2 (en) 2015-02-09 2019-10-29 Research Development Foundation Engineered immunoglobulin Fc polypeptides displaying improved complement activation
SG11201706730XA (en) 2015-02-17 2017-09-28 Dovetail Genomics Llc Nucleic acid sequence assembly
DK3262411T3 (da) 2015-02-25 2022-04-19 Univ Vanderbilt Antibody-mediated neutralization of marburg virus
WO2016135732A1 (en) 2015-02-26 2016-09-01 Yeda Research And Development Co. Ltd. Method of promoting hair growth
MY178919A (en) 2015-03-09 2020-10-23 Agensys Inc Antibody drug conjugates (adc) that bind to flt3 proteins
CN107614700A (zh) 2015-03-11 2018-01-19 布罗德研究所有限公司 基因型和表型偶联
US10781445B2 (en) 2015-03-11 2020-09-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Decoy oligonucleotides for the treatment of diseases
IL237852A0 (en) 2015-03-19 2016-03-24 Yeda Res & Dev Antibodies against amphigoline, medical preparations containing them and their use
WO2016154540A1 (en) 2015-03-26 2016-09-29 Dovetail Genomics Llc Physical linkage preservation in dna storage
US10028659B2 (en) 2015-03-26 2018-07-24 Verily Life Sciences Llc Aptamer-based sensors, implantable devices and detection system
WO2016157175A1 (en) 2015-03-27 2016-10-06 Yeda Research And Development Co. Ltd. Methods of treating motor neuron diseases
CA2981142A1 (en) 2015-03-27 2016-10-06 University Of Southern California Car t-cell therapy directed to lhr for the treatment of solid tumors
WO2016157190A1 (en) 2015-03-31 2016-10-06 Yeda Research And Development Co. Ltd. Glutamate oxaloacetate transaminase 1 (got1), preparations and methods of generating same and uses thereof
US9612534B2 (en) 2015-03-31 2017-04-04 Tokyo Electron Limited Exposure dose homogenization through rotation, translation, and variable processing conditions
WO2016157192A1 (en) 2015-04-01 2016-10-06 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Erodium crassifolium l'her plant extracts and uses thereof
US11965216B2 (en) 2015-04-07 2024-04-23 Polyskope Labs Detection of one or more pathogens
DK3280401T3 (da) 2015-04-07 2021-11-15 Ela Pharma Ltd Sammensætninger til behandling og/eller forebyggelse af celle- eller vævsnekrose specielt rettet mod kathepsin c og/eller cela1 og/eller cela3a og/eller strukturelt relaterede enzymer dertil
EP3081575A1 (en) 2015-04-12 2016-10-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Anti-plasmodium parasite antibodies
WO2016168750A1 (en) 2015-04-15 2016-10-20 Biosearch Technologies, Inc. Dual quencher probes
CN108135863B (zh) 2015-04-27 2021-07-27 特拉维夫医疗中心医学研究基础设施和保健服务基金会 用于治疗炎性和过度增殖性病况的egr1靶向分子
US10674732B2 (en) 2015-04-29 2020-06-09 The State Of Israel, Ministry Of Agriculture & Rural Development Agricultural Research Organization Anti-phytopathogenic compositions
US20190031759A1 (en) 2015-04-30 2019-01-31 Technion Research & Development Foundation Limited Chimeric antigen receptors and methods of their use
WO2016178207A1 (en) 2015-05-04 2016-11-10 Ramot At Tel-Aviv University Ltd. Methods and kits for fragmenting dna
CN106117288B (zh) 2015-05-08 2019-10-15 生捷科技控股公司 二硫键连接的可逆终止子
EP3294280A1 (en) 2015-05-11 2018-03-21 Yeda Research and Development Co., Ltd. Citrin inhibitors for the treatment of cancer
US11219636B2 (en) 2015-05-17 2022-01-11 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Compositions and methods for treating cancer
WO2016184902A1 (en) 2015-05-18 2016-11-24 Saga Diagnostics Ab Detection of target nucleic acid and variants
JP6857138B2 (ja) 2015-05-18 2021-04-14 アジェンシス，インコーポレイテッド Ａｘｌタンパク質に結合する抗体
US10787517B2 (en) 2015-05-18 2020-09-29 Agensys, Inc. Antibodies that bind to AXL proteins
WO2016185457A1 (en) 2015-05-19 2016-11-24 Yeda Research And Development Co. Ltd. Methods of promoting lymphangiogenesis
US10849985B2 (en) 2015-05-20 2020-12-01 Yeda Research And Development Co. Ltd. Method of targeting senescent cells
EP3297727A1 (en) 2015-05-21 2018-03-28 Yeda Research and Development Co. Ltd Bacterial populations for promoting health
MX2017015375A (es) 2015-05-29 2018-06-19 Opko Biologics Ltd Variantes de oxintomodulina pegilada.
UY36703A (es) 2015-06-02 2016-12-30 Monsanto Technology Llc Composiciones y métodos para la administración de un polinucleótido en una planta
CN108024517A (zh) 2015-06-03 2018-05-11 孟山都技术公司 用于将核酸引入到植物中的方法和组合物
JP7010473B2 (ja) 2015-06-04 2022-02-10 ユニバーシティ オブ サザン カリフォルニア Ｌｙｍ－１およびｌｙｍ－２標的化ｃａｒ細胞免疫療法
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
PL3307288T3 (pl) 2015-06-15 2019-12-31 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
TW202223083A (zh) 2015-06-15 2022-06-16 英商4D製藥研究有限公司 包含細菌菌株之組合物之用途
JP6439037B2 (ja) 2015-06-15 2018-12-19 フォーディー ファーマ リサーチ リミテッド４Ｄ Ｐｈａｒｍａ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ 細菌株を含む組成物
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
EP4026563A1 (en) 2015-06-18 2022-07-13 Yeda Research and Development Co. Ltd Conditioning protocols and use of same for tissue regeneration
WO2016203476A1 (en) 2015-06-18 2016-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods and compositions for diagnosing and treating urothelial cancer
KR102172937B1 (ko) 2015-06-19 2020-11-03 옵코 바이오로직스 리미티드 장기-작용성 응고 인자 및 그의 제조 방법
EP3314004A1 (en) 2015-06-26 2018-05-02 DuPont Nutrition Biosciences ApS Aminopeptidases for protein hydrolyzates
WO2017011329A1 (en) 2015-07-10 2017-01-19 West Virginia University Markers of stroke and stroke severity
AU2016291825B2 (en) 2015-07-16 2022-08-11 Yeda Research And Development Co. Ltd. Genetically modified anti-third party central memory T cells and use of same in immunotherapy
KR20210089270A (ko) 2015-07-16 2021-07-15 바이오카인 테라퓨틱스 리미티드 암 치료용 조성물 및 방법
EP3325494B1 (en) 2015-07-19 2020-12-30 Yeda Research and Development Co., Ltd. Selective inhibitors of alpha2-containing isoforms of na,k-atpase and use thereof for reducing intraocular pressure
WO2017015334A1 (en) 2015-07-21 2017-01-26 Saint Louis University Compositions and methods for diagnosing and treating endometriosis-related infertility
KR102460440B1 (ko) 2015-07-22 2022-10-28 피토파마 인터내셔널 리미티드 꿀벌―섭취가능한 조성물, 이를 이용한 꿀 생산 방법 및 이에 의해 생산된 꿀
EP3328995B1 (en) 2015-07-29 2021-03-31 Hadasit Medical Research Services And Development Large scale production of retinal pigment epithelial cells
US20180221393A1 (en) 2015-08-03 2018-08-09 Biokine Therapeutics Ltd. Cxcr4 binding agents for treatment of diseases
WO2017021961A1 (en) 2015-08-04 2017-02-09 Yeda Research And Development Co. Ltd. Methods of screening for riboswitches and attenuators
WO2017023929A1 (en) 2015-08-04 2017-02-09 Cd Diagnostics, Inc. Methods for detecting adverse local tissue reaction (altr) necrosis
EP3331994B1 (en) 2015-08-05 2022-09-14 Cell Cure Neurosciences Ltd. Preparation of retinal pigment epithelium cells
CA2993910A1 (en) 2015-08-05 2017-02-09 Cell Cure Neurosciences Ltd. Preparation of photoreceptors for the treatment of retinal diseases
WO2017024114A1 (en) 2015-08-06 2017-02-09 President And Fellows Of Harvard College Improved microbe-binding molecules and uses thereof
WO2017025963A1 (en) 2015-08-10 2017-02-16 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods and pharmaceutical compositions for improving wound healing using cd24
US20180237790A1 (en) 2015-08-13 2018-08-23 Forrest Innovation Ltd. Formulations and compositions for delivery of nucleic acids to plant cells
AU2016308339A1 (en) 2015-08-18 2018-04-12 Baylor College Of Medicine Methods and compositions for altering function and structure of chromatin loops and/or domains
WO2017033188A1 (en) 2015-08-24 2017-03-02 Yeda Research And Development Co. Ltd. Algal oil and biofuel and methods of producing same
ES2890073T3 (es) 2015-08-25 2022-01-17 Prothena Biosciences Ltd Métodos para detectar alfa-sinucleína fosforilada
WO2017040380A2 (en) 2015-08-28 2017-03-09 Research Development Foundation Engineered antibody fc variants
US11390908B2 (en) 2015-09-02 2022-07-19 University Of Massachusetts Detection of gene loci with CRISPR arrayed repeats and/or polychromatic single guide ribonucleic acids
US10765706B2 (en) 2015-09-03 2020-09-08 University Of South Florida Method of stem cell delivery into the brain during chronic disease using blood brain barrier permeabilizers
US11453864B2 (en) 2015-09-08 2022-09-27 University Of Massachusetts DNase H activity of Neisseria meningitidis Cas9
WO2017042814A1 (en) 2015-09-10 2017-03-16 Yeda Research And Development Co. Ltd. Use of perforin positive immature dendritic cells in disease treatment
US11001872B2 (en) 2015-09-22 2021-05-11 Shawn Clark Designing customized protein-specific buffer system
JP6836586B2 (ja) 2015-09-29 2021-03-03 エイチティージー モレキュラー ダイアグノスティクス， インコーポレイテッド びまん性大細胞型ｂ細胞性リンパ腫（ｄｌｂｃｌ）を亜型決定するための方法
EP3347373A1 (en) 2015-10-10 2018-07-18 Intrexon Corporation Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12
EP3913068B1 (en) 2015-10-12 2023-08-02 Advanced Cell Diagnostics, Inc. In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto
JP7300831B2 (ja) 2015-10-19 2023-06-30 ダブテイル ゲノミクス エルエルシー ゲノムアセンブリ、ハプロタイプフェージング、および標的に依存しない核酸検出のための方法
WO2017072757A1 (en) 2015-10-25 2017-05-04 Yeda Research And Development Co. Ltd. Antibodies targeting quiescin sulfhydryl oxidase (qsox1) and uses of same
EP3368661B1 (en) 2015-10-26 2025-01-22 Cell Cure Neurosciences Ltd. Preparation of retinal pigment epithelium cells
CN109310648B (zh) 2015-10-27 2022-06-03 杰伊制药公司 用于治疗癌症的包含大麻二酚和第二治疗剂的组合物
IL242380A0 (en) 2015-10-29 2016-02-01 Yeda Res & Dev A method for inducing the division of cardiomyocytes and treating heart diseases
WO2017077539A1 (en) 2015-11-03 2017-05-11 Ariel-University Research And Development Company Ltd. Compositions for regeneration and repair of neural tissue
EP4382127A3 (en) 2015-11-09 2024-08-28 The Children's Hospital of Philadelphia Glypican 2 as a cancer marker and therapeutic target
EP3374524B1 (en) 2015-11-11 2025-01-29 Ramot at Tel-Aviv University Ltd. Methods of detecting 5-hydroxymethylcytosine and diagnosing of cancer
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB2561748B (en) 2015-11-20 2019-05-08 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
BR112018010946A2 (pt) 2015-11-30 2018-12-04 Kadimastem Ltd método para enriquecimento de células endócrinas pancreáticas, população enriquecida de células endócrinas pancreáticas, método de tratamento de diabetes e método de preparação de células beta de produção de insulina
EP3909983A1 (en) 2015-12-02 2021-11-17 STCube & Co. Inc. Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof
EP3383908A1 (en) 2015-12-02 2018-10-10 Stsciences, Inc. Antibodies specific to glycosylated btla (b- and t- lymphocyte attenuator)
EP3176183A1 (en) 2015-12-02 2017-06-07 Yeda Research and Development Co. Ltd Compositions and methods for treating cancer not resistant to a tyrosine kinase inhibitor (tki)
EP3383418B1 (en) 2015-12-04 2021-10-20 Board of Regents, The University of Texas System Slc45a2 peptides for immunotherapy
ES2924732T3 (es) 2015-12-16 2022-10-10 Univ Ramot Partículas que comprenden epiplón descelularizado
JOP20200228A1 (ar) 2015-12-21 2017-06-16 Novartis Ag تركيبات وطرق لخفض تعبير البروتين tau
EP3393524B1 (en) 2015-12-22 2022-04-06 The Regents of The University of Colorado, A Body Corporate Protecting rnas from degradation using engineered viral rnas
EP3397344A4 (en) 2015-12-28 2019-08-28 B.G. Negev Technologies and Applications Ltd. at Ben-Gurion University COMPOSITION AND METHOD FOR THE TREATMENT OF AMYOTROPHER LATERAL SCLEROSIS
US10828318B2 (en) 2016-01-06 2020-11-10 Yeda Research And Development Co. Ltd. Compositions and methods for treating malignant, autoimmune and inflammatory diseases
WO2017122203A1 (en) 2016-01-11 2017-07-20 Technion Research & Development Foundation Limited Methods of determining prognosis of sepsis and treating same
JP7019580B2 (ja) 2016-01-21 2022-02-15 ザ ステイト オブ イスラエル ミニストリー オブ アグリカルチャー アンド ルーラル ディベロップメント アグリカルチュラル リサーチ オーガニゼイション （エー．アール．オー．） （ボルカニ センター） 単為結実植物およびその製造方法
IL243839B (en) 2016-01-28 2018-01-31 Sp Nano Ltd Conductive wires
IL243838A (en) 2016-01-28 2017-07-31 Sp Nano Ltd The composition containing sp1 protein and carbon nanoparticles and its uses
WO2017130205A1 (en) 2016-01-31 2017-08-03 Hadasit Medical Research Services And Development Ltd. Autosomal-identical pluripotent stem cell populations having non-identical sex chromosomal composition and uses thereof
CN108884137B (zh) 2016-02-04 2022-04-05 耶达研究及发展有限公司 肽及其在治疗与突变型p53相关的疾病、病症或病况中的用途
EP3414338B1 (en) 2016-02-11 2022-12-21 Qiagen Sciences, LLC Polyphenolic additives in sequencing-by-synthesis
US10036011B2 (en) 2016-02-11 2018-07-31 Qiagen Waltham, Inc. Scavenger compounds for improved sequencing-by-synthesis
WO2017138008A2 (en) 2016-02-14 2017-08-17 Yeda Research And Development Co. Ltd. Methods of modulating protein exocytosis and uses of same in therapy
ES2771223T3 (es) 2016-02-14 2020-07-06 Yeda Res & Dev Diagnóstico, predicción y tratamiento de la obesidad recidivante basados en el microbioma
MX2018009984A (es) 2016-02-16 2019-01-21 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Análogos no proteínicos de fenilananina para la inhibicion del crecimiento de cianobacterias y plantas.
EP3416671A4 (en) 2016-02-19 2019-10-30 Genisphere, LLC NUCLEIC ACID CARRIER AND THERAPEUTIC METHODS OF USE
US20200200735A9 (en) 2016-02-22 2020-06-25 Ursure, Inc. System and method for detecting therapeutic agents to monitor adherence to a treatment regimen
CN109072298B (zh) 2016-02-23 2022-04-08 多弗泰尔基因组学有限责任公司 用于基因组组装和单倍体型定相的定相读取集的生成
JP2019511919A (ja) 2016-02-23 2019-05-09 ブローディ，チャヤ がん幹細胞の作製およびその使用
CA3013383A1 (en) 2016-02-25 2017-08-31 Dupont Nutrition Biosciences Aps Method for producing a protein hydrolysate employing an aspergillus fumigatus tripeptidyl peptidase
CN109071642B (zh) 2016-02-26 2022-08-09 德克萨斯大学体系董事会 连接蛋白(Cx)43半通道结合抗体及其用途
CN109071666B (zh) 2016-03-01 2022-06-28 耶路撒冷希伯来大学伊森姆研究发展有限公司 人脊髓灰质炎病毒受体(pvr)特异性抗体
IL287757B (en) 2016-03-03 2022-07-01 Memed Diagnostics Ltd Analyzing rna for diagnosing infection type
CN108883139B (zh) 2016-03-04 2022-04-26 4D制药有限公司 包含细菌菌株的组合物
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
WO2017153982A1 (en) 2016-03-06 2017-09-14 Yeda Research And Development Co. Ltd. Method for modulating myelination
IL244649A0 (en) 2016-03-17 2016-06-30 Yeda Res & Dev Methods for the isolation of barrel-like proteases and the identification of peptides that are cleaved by Alidan
CN109641935A (zh) 2016-03-25 2019-04-16 莫拉利达尔·瑞迪·穆拉 组合合成和生物标志物开发
ES2883297T3 (es) 2016-03-29 2021-12-07 Stcube Inc Anticuerpos de función doble específicos para PD-L1 glucosilado y métodos de uso de los mismos
US11046782B2 (en) 2016-03-30 2021-06-29 Musc Foundation For Research Development Methods for treatment and diagnosis of cancer by targeting glycoprotein A repetitions predominant (GARP) and for providing effective immunotherapy alone or in combination
WO2017175228A1 (en) 2016-04-06 2017-10-12 Technion Research & Development Foundation Limited Infiltrating immune cell proportions predict anti-tnf response in colon biopsies
US10421785B2 (en) 2016-04-11 2019-09-24 Bar-Ilan University Delta receptor agonist peptides and use thereof
CA3232826A1 (en) 2016-04-27 2017-11-02 Gen-Probe Incorporated Blood cell lysis reagent
WO2017194589A1 (en) 2016-05-10 2017-11-16 Vib Vzw Inhibition of tau-mediated early synaptic dysfunction
KR102412442B1 (ko) 2016-05-13 2022-06-22 더브테일 제노믹스 엘엘씨 보존된 샘플로부터의 장범위 링키지 정보의 회수
EP3458483A1 (en) 2016-05-16 2019-03-27 President and Fellows of Harvard College Aqueous biomolecule coupling on co2-plasma-activated surfaces
WO2017203520A1 (en) 2016-05-22 2017-11-30 Yeda Research And Development Co. Ltd. Methods of using pulmonary cells for transplantation and induction of tolerance
IL245861A0 (en) 2016-05-25 2016-09-04 Yeda Res & Dev Use of substances to treat drug-resistant tumors
WO2017208247A1 (en) 2016-06-02 2017-12-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Assay for the removal of methyl-cytosine residues from dna
EP3464322B1 (en) 2016-06-05 2023-04-05 Tel HaShomer Medical Research Infrastructure and Services Ltd. Novel molecules for the treatment of inflammation
WO2017214068A1 (en) 2016-06-05 2017-12-14 Berg Llc Systems and methods for patient stratification and identification of potential biomarkers
EP3468610A1 (en) 2016-06-09 2019-04-17 OPKO Biologics Ltd. Long-acting oxyntomodulin formulation and methods of producing and administering same
US11859232B2 (en) 2016-06-19 2024-01-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Screening for chemotherapy resistance in human haploid cells
SG11201811563RA (en) 2016-06-27 2019-01-30 Yeda Res & Dev Veto cells generated from memory t cells
CN109416357B (zh) 2016-06-30 2022-07-15 西门子医疗系统荷兰有限公司 用于检测包含多个细胞的体液样本中的分析物的设备、系统和方法
DK3478832T3 (da) 2016-07-01 2022-05-30 Carlsberg As Fremgangsmåde til at screene for en mutant i en population af organismer ved at anvende en pooling- og splitting-tilgang
EP4184167A1 (en) 2016-07-10 2023-05-24 MeMed Diagnostics Ltd. Early diagnosis of infections
CA3027341A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
IL246722A0 (en) 2016-07-11 2016-09-29 Yeda Res & Dev Combination therapy to increase endogenous nitric oxide (no) synthesis
KR20190038833A (ko) 2016-07-11 2019-04-09 보누스 테라퓨틱스 리미티드 조직 재생용 세포 조성물
CN109563145B (zh) 2016-07-11 2024-01-26 Opko生物科学有限公司 长效凝血因子及其制备方法
EP3481191A2 (en) 2016-07-11 2019-05-15 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Systems and methods for growing cells in vitro
TWI802545B (zh) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
EP4434516A3 (en) 2016-07-18 2025-02-26 Ramot at Tel-Aviv University Ltd. Modular platform for targeted therapeutics
AU2017300579B2 (en) 2016-07-20 2023-02-09 Katholieke Universiteit Leuven, K.U.Leuven R&D Therapeutic agents for neurological and psychiatric disorders
KR20190031299A (ko) 2016-07-20 2019-03-25 주식회사 에스티큐브 글리코실화된 pd-l1에 결합하는 항체의 조합을 사용하는 암 치료 방법
US20190203270A1 (en) 2016-07-24 2019-07-04 Yeda Research And Development Co., Ltd. Methods and kits for analyzing dna binding moieties attached to dna
WO2018029682A1 (en) 2016-08-08 2018-02-15 Ramot At Tel-Aviv University Ltd. Bacterial systems for analyzing ubiquitylated polypeptides
WO2018029690A1 (en) 2016-08-10 2018-02-15 Memed Diagnostics Ltd. System and method for analysis of biological data
EP3497239A4 (en) 2016-08-10 2020-02-26 Ramot at Tel-Aviv University Ltd. METHYLATION STATUS ANALYSIS AND COPY NUMBER
US11129852B2 (en) 2016-08-14 2021-09-28 Ramot At Tel Aviv University Ltd. Mesenchymal cell-derived exosomes to treat neurological disorders
IL247368A0 (en) 2016-08-18 2016-11-30 Yeda Res & Dev Diagnostic and therapeutic uses of exosomes
WO2018037416A1 (en) 2016-08-25 2018-03-01 Yeda Research And Development Co. Ltd. Methods and compositions for treating autoimmune diseases
BR112019004180A2 (pt) 2016-08-28 2019-05-28 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization A R O método de controle de infecções fúngicas em plantas.
EP3510047A1 (en) 2016-09-07 2019-07-17 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Anti-nkp46 antibodies and therapeutic use of same
WO2018051347A1 (en) 2016-09-14 2018-03-22 Yeda Research And Development Co. Ltd. Crisp-seq, an integrated method for massively parallel single cell rna-seq and crispr pooled screens
US11385241B2 (en) 2016-09-29 2022-07-12 Memed Diagnostics Ltd. Methods of prognosis and treatment
IL248468A0 (en) 2016-10-13 2017-01-31 Technion Res & Dev Foundation Use of caspase-3 inhibitors and caspase-3 activators in the manufacture of medicament for treating cancer and wound healing
IL248385A0 (en) 2016-10-18 2017-02-01 Yeda Res & Dev Treatment of circadian rhythm disorder
WO2018085400A1 (en) 2016-11-02 2018-05-11 Vanderbilt University Human zika virus antibodies and methods of use therefor
WO2018085679A1 (en) 2016-11-04 2018-05-11 Stave James W Direct detection of microorganisms in patient samples by immunoassay
CN110121563A (zh) 2016-11-09 2019-08-13 奇根科学有限责任公司 在边合成边测序中作为成像试剂的光保护混合物
WO2018087759A1 (en) 2016-11-10 2018-05-17 Yeda Research And Development Co. Ltd. Phosphotriesterases for treating or preventing organophosphate exposure associated damage
AU2017363299B2 (en) 2016-11-23 2022-12-22 Chemocentryx, Inc. Method of treating focal segmental glomerulosclerosis
US11542508B2 (en) 2016-11-28 2023-01-03 Yeda Research And Development Co. Ltd. Isolated polynucleotides and polypeptides and methods of using same for expressing an expression product of interest
EP3548637A1 (en) 2016-11-29 2019-10-09 Genomic Vision Method for designing a set of polynucleotide sequences for analysis of specific events in a genetic region of interest
WO2018100574A1 (en) 2016-11-30 2018-06-07 Yeda Research And Development Co. Ltd. Methods of treating liver toxicity and disorders
WO2018100511A1 (en) 2016-12-01 2018-06-07 Ramot At Tel-Aviv University Ltd. Combined treatment for nerve injuries
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
IL267836B2 (en) 2017-01-04 2023-09-01 Complete Genomics Inc Stepwise sequence determination by unlabeled reversible terminations or natural nucleotides
WO2018134824A1 (en) 2017-01-18 2018-07-26 Yeda Research And Development Co. Ltd. Genetically modified veto cells and use of same in immunotherapy
RU2665631C2 (ru) 2017-01-25 2018-09-03 Общество с ограниченной ответственностью "Секвойя Дженетикс" Способ специфической идентификации последовательностей днк
CA3050859A1 (en) 2017-01-25 2018-08-02 Mor Research Applications Ltd. Methods of diagnosing malignant diseases
US11267885B2 (en) 2017-01-26 2022-03-08 Zlip Holding Limited CD47 antigen binding unit and uses thereof
CA3049778C (en) 2017-01-26 2024-06-18 Oklahoma Medical Research Foundation Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare
CA3051466A1 (en) 2017-01-31 2018-08-09 Vanderbilt University Generation of human allergen-and helminth-specific ige monoclonal antibodies for diagnostic and therapeutic use
IL250479A0 (en) 2017-02-06 2017-03-30 Sorek Rotem Genetically engineered cells expressing a disarm system that confers resistance to phages and methods for their production
US12281328B2 (en) 2017-02-08 2025-04-22 Hadasit Medical Research Services And Development Ltd. Photoreceptor cells for the treatment of retinal diseases
IL250916A0 (en) 2017-03-02 2017-06-29 Geiger Benjamin Methods for growing t cells in culture and their use
US11179413B2 (en) 2017-03-06 2021-11-23 Novartis Ag Methods of treatment of cancer with reduced UBB expression
WO2018167778A1 (en) 2017-03-12 2018-09-20 Yeda Research And Development Co. Ltd. Methods of diagnosing and prognosing cancer
WO2018167780A1 (en) 2017-03-12 2018-09-20 Yeda Research And Development Co. Ltd. Methods of prognosing and treating cancer
US20200085882A1 (en) 2017-03-16 2020-03-19 Lineage Cell Therapeutics, Inc. Methods for measuring therapeutic effects of retinal disease therapies
EP4317971A3 (en) 2017-04-05 2024-04-17 Yeda Research and Development Co. Ltd Ex-vivo culture system and methods of using same
CN108823287B (zh) 2017-04-28 2019-04-12 厦门大学 一种检测靶核酸序列的方法
IL252151A0 (en) 2017-05-07 2017-07-31 Fainzilber Michael Treatment of stress disorders
US20210003570A1 (en) 2017-05-10 2021-01-07 Rowan University Diagnostic biomarkers for detecting, subtyping, and/or assessing progression of multiple sclerosis
WO2018207184A2 (en) 2017-05-10 2018-11-15 Ariel Scientific Innovations Ltd. Methods of purifying antibodies
ES2939298T3 (es) 2017-05-21 2023-04-20 Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct Combinación de marcadores para el diagnóstico del cáncer
HRP20210780T1 (hr) 2017-05-22 2021-09-03 4D Pharma Research Limited Pripravci koji sadrže bakterijske sojeve
WO2018216011A1 (en) 2017-05-23 2018-11-29 Technion Research & Development Foundation Limited Agents which inhibit gads dimerization and methods of use thereof
WO2018215782A1 (en) 2017-05-24 2018-11-29 4D Pharma Research Limited Compositions comprising bacterial strain
CA3065301A1 (en) 2017-05-31 2018-12-06 Stcube & Co., Inc. Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof
GB201708665D0 (en) 2017-05-31 2017-07-12 Tropic Biosciences Uk Ltd Compositions and methods for increasing extractability of solids from coffee beans
EP3630973A1 (en) 2017-05-31 2020-04-08 Tropic Biosciences UK Limited Methods of selecting cells comprising genome editing events
GB201708662D0 (en) 2017-05-31 2017-07-12 Tropic Biosciences Uk Ltd Compositions and methods for increasing shelf-life of banana
CN111051346A (zh) 2017-05-31 2020-04-21 斯特库伯株式会社 使用免疫特异性结合btn1a1的抗体和分子治疗癌症的方法
WO2018226671A1 (en) 2017-06-06 2018-12-13 Stcube & Co., Inc. Methods of treating cancer using antibodies and molecules that bind to btn1a1 or btn1a1-ligands
ES2826394T3 (es) 2017-06-09 2021-05-18 Siemens Healthcare Diagnostics Products Gmbh Ensayo de activación para el diagnóstico de una trombocitopenia inducida por heparina
WO2018229764A1 (en) 2017-06-13 2018-12-20 Yeda Research And Development Co. Ltd. Treatment of advanced or progressive multiple sclerosis
TW201919670A (zh) 2017-06-14 2019-06-01 英商4D製藥研究有限公司 包含細菌品系之組成物
SG11201912156QA (en) 2017-06-14 2020-01-30 4D Pharma Res Ltd Compositions comprising bacterial strains
HRP20210205T1 (hr) 2017-06-14 2021-03-19 4D Pharma Research Limited Sastavi koji sadrže bakterijske sojeve
US12140592B2 (en) 2017-06-16 2024-11-12 Oklahoma Medical Research Foundation Biomarkers for assessing risk of transitioning to systemic lupus erythematosus classification and disease pathogenesis
US20200340057A1 (en) 2017-07-13 2020-10-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Dna targets as tissue-specific methylation markers
EP3652343A1 (en) 2017-07-13 2020-05-20 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Dual-probe digital droplet pcr strategy for specific detection of tissue-specific circulating dna molecules
EP3652342A1 (en) 2017-07-13 2020-05-20 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Detecting tissue-specific dna
US10768185B2 (en) 2017-07-20 2020-09-08 Trustees Of Boston University Tenofovir detection assay
EP3655004A2 (en) 2017-07-21 2020-05-27 Novartis AG Compositions and methods to treat cancer
IL253642A0 (en) 2017-07-24 2017-09-28 Seger Rony Combined treatment for cancer
EP3438667B1 (de) 2017-08-02 2020-12-30 Siemens Healthcare Diagnostics Products GmbH Bindungstest zur diagnose einer heparin-induzierten thrombozytopenie
IL253984A0 (en) 2017-08-14 2017-09-28 Yeda Res & Dev Immunotherapy against aranviruses that bind through transferrin receptor 1 (tfr1
EP3668884B1 (en) 2017-08-17 2022-03-09 ELITechGroup Inc. Duplex stabilizing fluorescence quenchers for nucleic acid probes
US11619634B2 (en) 2017-08-21 2023-04-04 Savicell Diagnostic Ltd. Methods of diagnosing and treating lung cancer
WO2019038771A1 (en) 2017-08-23 2019-02-28 Technion Research & Development Foundation Limited COMPOSITIONS AND METHODS FOR ENHANCING ALCOHOL TOLERANCE IN YEAST
CR20250168A (es) 2017-08-25 2025-06-20 Five Prime Therapeutics Inc Anticuerpos de b7-h4 y métodos para usarlos
EP3676400A4 (en) 2017-08-31 2021-06-02 Seegene, Inc. Evaluation of performance of components using a pair of dimer-forming primers
KR102678252B1 (ko) 2017-09-01 2024-06-26 쓰촨 케룬-바이오테크 바이오파마수티컬 컴퍼니 리미티드 재조합 이중특이적 항체
US20200407421A1 (en) 2017-09-05 2020-12-31 GLAdiator Biosciences, Inc. Delivery of payloads to stem cells
DE112018005145T5 (de) 2017-09-15 2020-07-23 The Regents Of The University Of California Hemmung von aminoacylase 3 (aa3) bei der behandlung von krebs
SG11202002481RA (en) 2017-09-19 2020-04-29 Tropic Biosciences Uk Ltd Modifying the specificity of non-coding rna molecules for silencing gene expression in eukaryotic cells
US20200214273A1 (en) 2017-09-19 2020-07-09 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization Genome-edited birds
CN111868039A (zh) 2017-09-26 2020-10-30 加利福尼亚大学董事会 用于治疗癌症的组合物和方法
US11401546B2 (en) 2017-09-29 2022-08-02 Seegene, Inc. Detection of target nucleic acid sequences by PTO cleavage and extension-dependent extension assay
EP3692152B1 (en) 2017-10-04 2025-09-03 The Broad Institute, Inc. Methods and compositions for altering function and structure of chromatin loops and/or domains
KR20200070299A (ko) 2017-10-11 2020-06-17 케모센트릭스, 인크. Ccr2 길항제에 의한 국소 분절 사구체경화증의 치료
EP3694545A4 (en) 2017-10-11 2021-12-01 Board Of Regents, The University Of Texas System HUMAN PD-L1 ANTIBODIES AND PROCEDURES FOR USE
CN111565731B (zh) 2017-10-24 2024-03-08 达莉亚·伊兰妮 治疗缺血性疾病的方法
CA3082365A1 (en) 2017-11-09 2019-05-16 Pinteon Therapeutics Inc. Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies
IL255664A0 (en) 2017-11-14 2017-12-31 Shachar Idit Hematopoietic stem cells with enhanced properties
US20200390800A1 (en) 2017-11-29 2020-12-17 Ramot At Tel-Aviv University Ltd. Methods of preventing or treating neurogenic shock
BR112020010830A2 (pt) 2017-11-29 2020-11-10 Weedout Ltd. composições, kits e métodos para controlar erva daninha do gênero amaranthus
EP3716993A1 (en) 2017-12-03 2020-10-07 Yeda Research and Development Co. Ltd Treatment of an ischemic heart disease
CN109870581B (zh) 2017-12-04 2021-05-04 厦门万泰凯瑞生物技术有限公司 一种定量检测HBsAg的试剂盒及方法
WO2019118721A2 (en) 2017-12-15 2019-06-20 Syngenta Participations Ag Non-antibody ligands for detecting target proteins
EP3723785A1 (en) 2017-12-17 2020-10-21 Yeda Research and Development Co. Ltd Cop9 signalosome (csn) complex modulators and uses thereof
WO2019130313A1 (en) 2017-12-28 2019-07-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method to reproduce circadian rhythms on a microfluidic chip
WO2019156758A2 (en) 2018-01-05 2019-08-15 Vanderbilt University Antibody-mediated neutralization of chikungunya virus
EP3514541A1 (de) 2018-01-17 2019-07-24 Siemens Healthcare Diagnostics Products GmbH Verfahren zur quantitativen bestimmung eines therapeutischen tnf-alpha inhibitors
IL257225A (en) 2018-01-29 2018-04-09 Yeda Res & Dev Treatment of sarcoma
EP3745846A4 (en) 2018-01-29 2022-04-06 Lavie Bio Ltd. VEGETABLE MICROBIAL PREPARATIONS, COMPOSITIONS AND FORMULATIONS COMPRISING THEM AND THEIR USES
IL257269A (en) 2018-01-31 2018-04-09 Olender Tsviya Signaling is directed to the endoplasmic reticulum
US12378592B2 (en) 2018-01-31 2025-08-05 Dovetail Genomics, Llc. Sample prep for DNA linkage recovery
WO2019155459A1 (en) 2018-02-08 2019-08-15 Yeda Research And Development Co. Ltd. Inhibitors of the 20s proteasome
WO2019155465A1 (en) 2018-02-08 2019-08-15 Yeda Research And Development Co. Ltd. Methods of identifying and using agents for treating diseases associated with intestinal barrier dysfunction
WO2019155041A1 (en) 2018-02-12 2019-08-15 Vib Vzw Gβγ COMPLEX ANTIBODIES AND USES THEREOF
WO2019165217A1 (en) 2018-02-22 2019-08-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cd153 and/or cd30 in infection
EP3755340A4 (en) 2018-02-23 2021-11-17 Carmel-Haifa University Economic Corporation Ltd. METHODS OF TREATING MEMORY DISORDER AND COGNITIVE DYSFUNCTION
EP3759493A1 (en) 2018-02-28 2021-01-06 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods of diagnosing and treating bladder cancer
EA202091810A1 (ru) 2018-03-02 2021-01-29 Файв Прайм Терапьютикс, Инк. Антитела к b7-h4 и способы их применения
EP3765034A1 (en) 2018-03-12 2021-01-20 Yeda Research and Development Co. Ltd Treatment of a heart disease
CA3092687A1 (en) 2018-03-23 2019-09-26 Board Of Regents, The University Of Texas System Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor
EP4501355A3 (en) 2018-03-23 2025-04-30 Board Of Regents, The University Of Texas System Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor
WO2019186558A1 (en) 2018-03-29 2019-10-03 Technion Research And Development Foundation Limited Vesicles comprising a pten inhibitor and uses of same
IL258467A (en) 2018-03-29 2018-07-04 Ilana Kolodkin Gal Methods of disrupting a biofilm and/or preventing formation of same
WO2019186569A1 (en) 2018-03-29 2019-10-03 Yeda Research And Development Co. Ltd. Use of electric field gradients to control gene expression
CN112292457A (zh) 2018-04-09 2021-01-29 领先细胞医疗诊断有限公司 用于原位检测核酸的进一步增强信号放大的方法
WO2019203623A1 (en) 2018-04-20 2019-10-24 Seegene, Inc. . Method and apparatus for detecting a plurality of target nucleic acid sequences in sample
KR20210027254A (ko) 2018-04-24 2021-03-10 앰프소스 바이오파마 상하이 인코포레이티드 Tim-3에 대한 항체 및 그의 용도
GB201807192D0 (en) 2018-05-01 2018-06-13 Tropic Biosciences Uk Ltd Compositions and methods for reducing caffeine content in coffee beans
EP3788138A1 (en) 2018-05-02 2021-03-10 Novartis AG Regulators of human pluripotent stem cells and uses thereof
WO2019220441A1 (en) 2018-05-15 2019-11-21 Hadasit Medical Research Services And Development Ltd. Compositions and methods for treating cancer resistant to an anti-cancer agent
IL259392A (en) 2018-05-15 2018-08-01 Yeda Res & Dev Vaccination with cancer neoantigens
CA3099383A1 (en) 2018-05-27 2019-12-05 Biolinerx Ltd. Agi-134 combined with a checkpoint inhibitor for the treatment of solid tumors
WO2019231617A1 (en) 2018-05-29 2019-12-05 Elitechgroup, Inc. Carborhodamine compounds and methods of preparation thereof
CN112424365A (zh) 2018-06-07 2021-02-26 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 核酸构建体及其使用方法
US20210337753A1 (en) 2018-06-07 2021-11-04 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization Methods of regenerating and transforming cannabis
US12129298B2 (en) 2018-06-21 2024-10-29 Daiichi Sankyo Company, Limited Compositions including CD3 antigen binding fragments and uses thereof
US11873322B2 (en) 2018-06-25 2024-01-16 Yeda Research And Development Co. Ltd. Systems and methods for increasing efficiency of genome editing
US20210292381A1 (en) 2018-07-04 2021-09-23 Ukko Inc. Methods of de-epitoping wheat proteins and use of same for the treatment of celiac disease
EP3818529A2 (en) 2018-07-08 2021-05-12 Yeda Research and Development Co. Ltd Person-specific assessment of probiotics responsiveness
WO2020012486A1 (en) 2018-07-11 2020-01-16 Kahr Medical Ltd. SIRPalpha-4-1BBL VARIANT FUSION PROTEIN AND METHODS OF USE THEREOF
AU2019300567B2 (en) 2018-07-11 2024-09-19 Immunity Pharma Ltd. Peptide compounds and therapeutic uses of same
KR20210042430A (ko) 2018-07-31 2021-04-19 콜플랜트 리미티드 담배 형질전환 이벤트 및 이의 검출 방법 및 용도
IL261156A (en) 2018-08-14 2020-02-27 Fass Deborah Chimeric quiescin sulfhydryl oxidase (qsox1) antibodies and uses of same
WO2020039440A1 (en) 2018-08-24 2020-02-27 Yeda Research And Development Co. Ltd. Methods of modulating m2 macrophage polarization and use of same in therapy
CN112672760B (zh) 2018-09-13 2025-05-30 德克萨斯大学体系董事会 新颖lilrb4抗体和其用途
US20210353611A1 (en) 2018-09-20 2021-11-18 Yeda Research And Development Co. Ltd. Methods of treating amyotrophic lateral sclerosis
EP3856225A1 (en) 2018-09-25 2021-08-04 BioLineRx Ltd. Methods of selecting treatment for cxcr4-associated cancer
WO2020069424A1 (en) 2018-09-28 2020-04-02 Centrillion Technologies, Inc. Disulfide-linked reversible terminators
KR102220701B1 (ko) 2018-09-28 2021-03-03 (주)나노헬릭스 형광기반의 다중 융해 분석을 이용한 증폭 산물의 다중 분석방법
EP3867367A1 (en) 2018-10-15 2021-08-25 University Of Massachusetts Programmable dna base editing by nme2cas9-deaminase fusion proteins
CA3116539C (en) 2018-10-18 2023-10-03 Oklahoma Medical Research Foundation Biomarkers for a systemic lupus erythematosus (sle) disease activity immune index that characterizes disease activity
MX2021004588A (es) 2018-10-22 2022-01-18 Shanghai Genbase Biotechnology Co Ltd Anticuerpo anti-cldn18.2 y sus usos.
WO2020083979A1 (en) 2018-10-23 2020-04-30 Glycardial Diagnostics, S.L. Antibodies specific for glycosylated apoj and uses thereof
IL262658A (en) 2018-10-28 2020-04-30 Memorial Sloan Kettering Cancer Center Prevention of age related clonal hematopoiesis and diseases associated therewith
CN111196851B (zh) 2018-11-20 2021-11-16 厦门万泰凯瑞生物技术有限公司 针对人抗缪勒管激素的特异性抗体及其应用
IL263184A (en) 2018-11-21 2020-05-31 Yarden Yosef Method of treating cancer and compositions for same
JP7478149B2 (ja) 2018-11-28 2024-05-02 オレゴン ヘルス アンド サイエンス ユニバーシティー 治療用第ｘｉｉ因子抗体
MX2021006234A (es) 2018-11-30 2021-09-10 Caris Mpi Inc Perfilado molecular de proxima generacion.
CN113166246B (zh) 2018-12-28 2024-10-18 四川科伦博泰生物医药股份有限公司 一种抗体及其用途
WO2020152686A1 (en) 2019-01-23 2020-07-30 Yeda Research And Development Co. Ltd. Culture media for pluripotent stem cells
JP7692355B2 (ja) 2019-01-25 2025-06-13 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 核酸を合成するための組成物および方法
IL264768A (en) 2019-02-10 2020-08-31 Sagi Irit ANTI-MATRIX METALLOPROTEINASE 7 (MMP-7) inhibitory antibody and its use
IL264854A (en) 2019-02-14 2020-08-31 Bahat Anat Spt5 inhibitors and methods of use thereof
US20220154262A1 (en) 2019-02-15 2022-05-19 Advanced Cell Diagnostics, Inc. Methods for multiplex detection of nucleic acids by in situ hybridization
EP3927378A1 (en) 2019-02-21 2021-12-29 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Method for reduction drug-induced nephrotoxicity
WO2020170239A1 (en) 2019-02-21 2020-08-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of generating organoids for high throughput screening of drugs
IL286011B2 (en) 2019-03-05 2024-06-01 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo Genome-edited birds
CA3133074A1 (en) 2019-03-11 2020-09-17 Memorial Sloan Kettering Cancer Center Cd22 antibodies and methods of using the same
GB201903519D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Introducing silencing activity to dysfunctional rna molecules and modifying their specificity against a gene of interest
GB201903520D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Modifying the specificity of non-coding rna molecules for silencing genes in eukaryotic cells
GB201903521D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd No title
IL265486A (en) 2019-03-19 2020-09-30 Yeda Res & Dev Bistable type ii opsins and uses thereof
WO2020194317A1 (en) 2019-03-28 2020-10-01 Yeda Research And Development Co. Ltd. Method of treating lipid-related disorders
EP3946611A2 (en) 2019-03-31 2022-02-09 Yeda Research and Development Co. Ltd Anti-viral and anti-tumoral compounds
EP3957652A4 (en) 2019-04-16 2023-06-21 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. ANTI-FXI/FXIA ANTIBODIES AND THEIR USE
CA3138566A1 (en) 2019-04-30 2020-11-05 Larimar Therapeutics, Inc. Frataxin-sensitive markers for determining effectiveness of frataxin replacement therapy
IL266433B (en) 2019-05-02 2020-11-30 Sagi Irit Preparations containing the propeptide of lysyl oxidase and their uses
EP3969619A1 (en) 2019-05-13 2022-03-23 Yeda Research and Development Co. Ltd Cell-free mirna biomarkers for prognosis and diagnosis of neurodegenerative diseases
IL266728B (en) 2019-05-19 2020-11-30 Yeda Res & Dev Identification of recurrent mutant neopeptides
JP7664856B2 (ja) 2019-05-22 2025-04-18 ハダシット メディカル リサーチ サービシーズ アンド ディベロップメント リミテッド ヒト多能性細胞を培養する方法
US20220251179A1 (en) 2019-05-28 2022-08-11 Shanghaitech University Composition and methods to treat ectodermal dysplasia 2, clouston type
US20220233477A1 (en) 2019-06-12 2022-07-28 Hadasit Medical Research Services And Development Ltd. Methods of generating oligodendrocytes
EP3983540A1 (en) 2019-06-16 2022-04-20 Yeda Research and Development Co. Ltd Method for stabilizing intracellular rna
EP3990488A4 (en) 2019-06-27 2023-09-13 Ramot at Tel-Aviv University Ltd. SEMAPHORIN 3A ANTIBODIES AND THEIR USES
CA3145212A1 (en) 2019-06-27 2020-12-30 Dovetail Genomics, Llc Methods and compositions for proximity ligation
CN114938647A (zh) 2019-07-04 2022-08-23 乌科公司 去表位的α-麦醇溶蛋白及其在乳糜泻和麸质敏感性管理中的用途
JP2022541742A (ja) 2019-07-11 2022-09-27 カール メディカル リミテッド ヘテロダイマーおよびその使用方法
WO2021009740A1 (en) 2019-07-16 2021-01-21 Ramot At Tel-Aviv University Ltd. Compositions and methods for the treatment of tuberculosis
IL268111A (en) 2019-07-16 2021-01-31 Fainzilber Michael Methods of treating pain
JP2022541538A (ja) 2019-07-19 2022-09-26 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア グリピカン２結合ドメインを含有するキメラ抗原受容体
KR20220038415A (ko) 2019-07-26 2022-03-28 벤더르빌트 유니버시티 엔테로바이러스 d68에 대한 인간 모노클로날 항체
EP4004548A1 (en) 2019-07-29 2022-06-01 Yeda Research and Development Co. Ltd Methods of treating and diagnosing lung cancer
US20220298522A1 (en) 2019-07-30 2022-09-22 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization Methods of controlling cannabinoid synthesis in plants or cells and plants and cells produced thereby
WO2021028909A1 (en) 2019-08-12 2021-02-18 Yeda Research And Development Co. Ltd. Dna repair blood test for predicting response of lung cancer patients to immunotherapy
WO2021033176A1 (en) 2019-08-22 2021-02-25 Ariel Scientific Innovations Ltd. Scaled-up methods for purifying antibodies
EP4021463A1 (en) 2019-08-27 2022-07-06 Yeda Research and Development Co. Ltd Treatment of bacterial vaginosis
WO2021048852A1 (en) 2019-09-11 2021-03-18 Yeda Research And Development Co. Ltd. Methods of treating breast cancer
JP2022547627A (ja) 2019-09-16 2022-11-14 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア Ｓｗｉ－ｓｎｆ変異型腫瘍の処置のための組成物および方法
WO2021051390A1 (zh) 2019-09-20 2021-03-25 上海吉倍生物技术有限公司 靶向bcma的抗体及嵌合抗原受体
IL269674B (en) 2019-09-25 2020-08-31 Roy Bar Ziv Assembling protein complexes on a chip
US20220411511A1 (en) 2019-09-26 2022-12-29 Stcube & Co. Antibodies specific to glycosylated ctla-4 and methods of use thereof
CN114206931B (zh) 2019-09-30 2024-06-04 四川科伦博泰生物医药股份有限公司 抗pd-1抗体及其用途
US20220356248A1 (en) 2019-10-09 2022-11-10 Stcube & Co Antibodies specific to glycosylated lag3 and methods of use thereof
IL292003A (en) 2019-10-10 2022-06-01 Carlsberg As A method for preparing mutant plants
WO2021080629A1 (en) 2019-10-23 2021-04-29 Elitechgroup, Inc. Methods for true isothermal strand displacement amplification
IL270306A (en) 2019-10-30 2021-05-31 Yeda Res & Dev Prevention and treatment of pre-myeloid and myeloid malignancies
WO2021084526A1 (en) 2019-10-31 2021-05-06 Yeda Research And Development Co. Ltd. Engineered autotrophic bacteria for co2 conversion to organic materials
CA3160506A1 (en) 2019-11-11 2021-05-20 Ibi-Ag Innovative Bio Insecticides Ltd. Insect control nanobodies and uses thereof
US12385054B2 (en) 2019-11-19 2025-08-12 Protalix Ltd. Removal of constructs from transformed cells
IL270800A (en) 2019-11-20 2021-05-31 Yeda Res & Dev A method for treating Alzheimer's disease
US10792360B1 (en) 2019-11-21 2020-10-06 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
EP4069865A4 (en) 2019-12-02 2023-12-20 Caris MPI, Inc. PLATINUM RESPONSE PREDICTOR IN A PAN-CANCER APPROACH
EP4073246A4 (en) 2019-12-12 2023-12-06 President And Fellows Of Harvard College COMPOSITIONS AND METHODS FOR LIGHT-DIRECTED BIOMOLECULAR BARCODING
MX2022004919A (es) 2019-12-13 2022-05-16 Sichuan Kelun Biotech Biopharmaceutical Co Ltd Anticuerpo anti-linfopoyetina estromal timica (tslp) y sus usos.
WO2021126435A1 (en) 2019-12-20 2021-06-24 Novarock Biotherapeutics, Ltd. Anti-interleukin-23 p19 antibodies and methods of use thereof
IL271656A (en) 2019-12-22 2021-06-30 Yeda Res & Dev System and methods for identifying cells that have undergone genome editing
EP4077731A1 (en) 2019-12-22 2022-10-26 Yeda Research and Development Co. Ltd Diagnosis of frontotemporal dementia
CN113046421B (zh) 2019-12-26 2022-09-30 厦门大学 一种不对称扩增靶核酸的方法
EP3842452A1 (en) 2019-12-26 2021-06-30 Universitat Autònoma de Barcelona Scaffold proteins and therapeutic nanoconjugates based on nidogen
CN113046420B (zh) 2019-12-26 2022-10-04 厦门大学 一种不对称扩增多个靶核酸的方法
IL271778A (en) 2019-12-31 2021-06-30 Ichilov Tech Ltd Methods for treating atopic dermatitis
US20230048719A1 (en) 2019-12-31 2023-02-16 Kahr Medical Ltd. Methods of culturing t cells with a 4-1bbl fusion polypeptide and uses of same
US20230048361A1 (en) 2019-12-31 2023-02-16 Kahr Medical Ltd. Methods of culturing t cells and uses of same
CN113061165A (zh) 2020-01-02 2021-07-02 厦门大学 EB病毒BNLF2b基因编码多肽及其检测用途
IL272074B2 (en) 2020-01-15 2024-12-01 Immunity Pharma Ltd Peptide compounds and methods of treating diseases using same
IL272194A (en) 2020-01-22 2021-07-29 Yeda Res & Dev Multi-target antibodies for use in the treatment of diseases
WO2021152584A1 (en) 2020-01-28 2021-08-05 Ariel Scientific Innovations Ltd. Methods of analyzing cell membranes
WO2021152595A1 (en) 2020-01-29 2021-08-05 Memed Diagnostics Ltd. Methods of diagnosing and classifying viral infections
IL272390A (en) 2020-01-30 2021-08-31 Yeda Res & Dev Cancer treatment methods
WO2021152586A1 (en) 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Methods of analyzing microbiome, immunoglobulin profile and physiological state
WO2021152587A1 (en) 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Treating acute liver disease with tlr-mik inhibitors
IL272389A (en) 2020-01-30 2021-08-31 Yeda Res & Dev Kits containing antibodies to PD-L1 and their uses in therapy
WO2021156490A2 (en) 2020-02-06 2021-08-12 Vib Vzw Corona virus binders
CA3170374A1 (en) 2020-02-09 2021-08-12 Nlc Pharma Ltd Rapid detection test for sars-cov-2
IL272586A (en) 2020-02-10 2021-08-31 Yeda Res & Dev A method for cell cluster analysis
CA3166949A1 (en) 2020-02-11 2021-08-19 James E. Crowe Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (sars-cov-2)
WO2021167908A1 (en) 2020-02-17 2021-08-26 Board Of Regents, The University Of Texas System Methods for expansion of tumor infiltrating lymphocytes and use thereof
CA3173090A1 (en) 2020-02-25 2021-09-02 Vib Vzw Leucine-rich repeat kinase 2 allosteric modulators
WO2021173674A1 (en) 2020-02-26 2021-09-02 A2 Biotherapeutics, Inc. Polypeptides targeting mage-a3 peptide-mhc complexes and methods of use thereof
US20230127559A1 (en) 2020-03-16 2023-04-27 Yeda Research And Development Co. Ltd. Peptide analogs and use of same in treating diseases, disorders or conditions associated with mutant p53 protein
WO2021188389A2 (en) 2020-03-17 2021-09-23 Genevant Sciences Gmbh Cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells
WO2021195385A1 (en) 2020-03-26 2021-09-30 Vanderbilt University HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-GoV-2)
PL4045533T3 (pl) 2020-03-26 2024-04-15 Vanderbilt University Ludzkie przeciwciała monoklonalne przeciwko ciężkiemu ostremu zespołowi oddechowemu wywołanemu koronawirusem 2 (sars-cov-2)
IL296696A (en) 2020-03-29 2022-11-01 Yeda res & development co ltd Variants of beta-glucocerebrosidase for the treatment of Gaucher disease
TW202203916A (zh) 2020-03-31 2022-02-01 美商卡默森屈有限公司 使用ｃｃｒ９抑制劑及抗ｉｌ—２３阻斷抗體治療發炎性腸道疾病的組成物及方法
WO2021199047A1 (en) 2020-03-31 2021-10-07 Biomuse Ltd. Bacteria for the prevention and treatment of smoke-induced lung damage
EP4133107A1 (en) 2020-04-06 2023-02-15 Yeda Research and Development Co. Ltd Methods of diagnosing cancer and predicting responsiveness to therapy
WO2021205459A1 (en) 2020-04-07 2021-10-14 Ramot At Tel-Aviv University Ltd. Cannabidiol-containing compositions and uses thereof
CN115666619A (zh) 2020-04-13 2023-01-31 埃索普罗瑟医疗有限公司 用于抗病毒治疗的包含野生型p53蛋白的细胞衍生囊泡
US20210322483A1 (en) 2020-04-16 2021-10-21 Ichilov Tech Ltd. Cell-derived particles presenting heterologous cd24 and use thereof in therapy
BR112022020949A2 (pt) 2020-04-17 2022-12-06 Idexx Lab Inc Imunoensaio de diminuição de fluorescência
AU2021261343A1 (en) 2020-04-22 2022-11-03 President And Fellows Of Harvard College Isothermal methods, compositions, kits, and systems for detecting nucleic acids
WO2021229577A1 (en) 2020-05-12 2021-11-18 Collplant Ltd. Collagen as a delivery tool for metal-based anti-viral agents
WO2021228141A1 (zh) 2020-05-15 2021-11-18 四川科伦博泰生物医药股份有限公司 抗体药物缀合物及其制备方法和用途
IL274811B (en) 2020-05-20 2021-05-31 Yeda Res & Dev Spatial information is developed for the analysis of individual cells
WO2021250677A1 (en) 2020-06-10 2021-12-16 Ramot At Tel-Aviv University Ltd. METHODS OF DETECTING METHYLATED CpG
EP4168438A4 (en) 2020-06-22 2024-07-10 Ramot at Tel-Aviv University Ltd. Multi subunit protein modules, cells expressing same and uses thereof
US20230293530A1 (en) 2020-06-24 2023-09-21 Yeda Research And Development Co. Ltd. Agents for sensitizing solid tumors to treatment
EP3939999A1 (en) 2020-07-14 2022-01-19 Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Interleukin 11 receptor alpha subunit (il11ra) neutralizing antibodies and uses thereof
IL276599A (en) 2020-08-09 2022-03-01 Yeda Res & Dev T cell receptor unique to mage-a1 and its uses
IL276627A (en) 2020-08-10 2022-03-01 Yeda Res & Dev Compositions for diagnosis and treatment of coronavirus infections
US20230309480A1 (en) 2020-08-18 2023-10-05 International Rice Research Institute Methods of increasing outcrossing rates in gramineae
EP4200440A4 (en) 2020-08-21 2024-10-09 Advanced Cell Diagnostics, Inc. COMPOSITIONS AND METHODS FOR DETERMINING T CELL CLONALITY
WO2022047359A1 (en) 2020-08-31 2022-03-03 Berg Llc Protein biomarkers for pancreatic cancer
IL277488A (en) 2020-09-21 2022-04-01 Yeda Res & Dev Weight regulation method
EP4217370A2 (en) 2020-09-23 2023-08-02 Yeda Research and Development Co. Ltd Methods and compositions for treating coronaviral infections
IL277743A (en) 2020-10-01 2022-04-01 Yeda Res & Dev A method for diagnosing breast cancer
WO2022074646A1 (en) 2020-10-05 2022-04-14 Protalix Ltd. Dicer-like knock-out plant cells
US20230416707A1 (en) 2020-10-07 2023-12-28 Protalix Ltd. Long-acting dnase
EP4225364A4 (en) 2020-10-09 2025-02-26 Board of Regents, The University of Texas System Prefusion-stabilized hmpv f proteins
EP4228637A1 (en) 2020-10-15 2023-08-23 Yeda Research and Development Co. Ltd Method of treating myeloid malignancies
IL278401A (en) 2020-10-29 2022-05-01 Yeda Res & Dev Polynucleotides for editing RNA and a method for using them
US20230416750A1 (en) 2020-11-09 2023-12-28 1E Therapeutics Ltd. Catalytic sequence based methods of treating or preventing bacterial infections
GB202105804D0 (en) 2020-11-20 2021-06-09 Univ Cape Town Use of microvirin in the identification of mycobacterium tuberculosis mannose-capped lipoarabinomannan
CA3200350A1 (en) 2020-11-26 2022-06-02 Yanay OFRAN Modified high molecular weight glutenin subunit and uses thereof
JP2023553877A (ja) 2020-12-04 2023-12-26 ユニバーシティ オブ テネシー リサーチ ファウンデーション アミロイド疾患を診断する方法
IL279559A (en) 2020-12-17 2022-07-01 Yeda Res & Dev Controlling ubiquitination of mlkl for treatment of disease
AU2021403156A1 (en) 2020-12-18 2023-07-13 Genevant Sciences Gmbh Peg lipids and lipid nanoparticles
EP4267741A2 (en) 2020-12-28 2023-11-01 1E Therapeutics, Ltd. P21 mrna target areas for silencing
KR20230133859A (ko) 2020-12-28 2023-09-19 1이 테라퓨틱스 엘티디. p21 mRNA 표적화 DNA자임
CN117043189A (zh) 2020-12-31 2023-11-10 诺纳生物（苏州）有限公司 人lifr抗原结合蛋白及其制备方法和应用
AU2022206415A1 (en) 2021-01-10 2023-08-17 Supermeat The Essence Of Meat Ltd. Pluripotent stem cell aggregates and microtissues obtained therefrom for the cultured meat industry
WO2022153286A1 (en) 2021-01-14 2022-07-21 Yeda Research And Development Co. Ltd. Methods of producing vitamin d
IL280340B (en) 2021-01-21 2022-04-01 Yeda Res & Dev Antibodies, peptides and their combinations for the treatment and prevention of corona virus infections
GB2603166A (en) 2021-01-29 2022-08-03 Thelper As Therapeutic and Diagnostic Agents and Uses Thereof
MX2023008895A (es) 2021-02-09 2023-08-09 Medilink Therapeutics Suzhou Co Ltd Conjugado de sustancia bioactiva, metodo de preparacion y uso del mismo.
EP4294429A1 (en) 2021-02-18 2023-12-27 Yeda Research and Development Co. Ltd Genetically modified bacteria for generating vaccines
JP2024506955A (ja) 2021-02-18 2024-02-15 イェダ リサーチ アンド デベロップメント カンパニー リミテッド ワクチンを作製する方法
IL305318A (en) 2021-02-19 2023-10-01 Vib Vzw Cation-independent mannose-6-phosphate receptor binders
JP7734753B2 (ja) 2021-03-05 2025-09-05 シャンハイ、ケンパーソー、バイオテクノロジー、カンパニー、リミテッド 抗ｃｌｄｎ６抗体およびその使用
JP2024512392A (ja) 2021-03-08 2024-03-19 イミュノジェン・インコーポレーテッド がんの治療のためのａｄａｍ９を標的とする免疫抱合体の有効性を増加させるための方法
CA3207635A1 (en) 2021-03-09 2022-09-15 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Ror1 binding protein and use thereof
IL281561A (en) 2021-03-16 2022-10-01 Yeda Res & Dev Methods and devices for ex-utero mouse embryonic development
JP2024514252A (ja) 2021-03-30 2024-03-29 バイオエムエックス・リミテッド Ｐｓｅｕｄｏｍｏｎａｓバクテリオファージ及びその使用
IL307528A (en) 2021-04-06 2023-12-01 Bpgbio Inc Protein markers for the prognosis of breast cancer progression
IL307531A (en) 2021-04-06 2023-12-01 Bpgbio Inc Protein markers for estrogen receptor (er)-positive-like and estrogen receptor (er)-negative-like breast cancer
EP4320440A1 (en) 2021-04-06 2024-02-14 BPGbio, Inc. Protein markers for estrogen receptor (er)-positive luminal a(la)-like and luminal b1 (lb1)-like breast cancer
IL282188A (en) 2021-04-08 2022-11-01 Yeda Res & Dev Combined use of ketamine and bretigabine for the treatment of psychiatric disorders
US20240212150A1 (en) 2021-04-16 2024-06-27 Advanced Cel Diagnostics, Inc. Materials and methods related to image processing
AU2022260794A1 (en) 2021-04-19 2023-11-23 Temple Therapeutics BV Methods for detecting or treating endometrial and ovarian hyperproliferative disorders
CA3218291A1 (en) 2021-05-12 2022-11-17 Lior Moshe ZELCBUCH Staphylococcus bacteriophage and uses thereof
IL283563A (en) 2021-05-30 2022-12-01 Yeda Res & Dev Profiling of amps for the diagnosis, monitoring and treatment of microbiome-related diseases
WO2022259242A1 (en) 2021-06-06 2022-12-15 Yeda Research And Development Co. Ltd. Combined treatment for cancer
WO2022264132A1 (en) 2021-06-13 2022-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method for reprogramming human cells
NL2028466B1 (en) 2021-06-16 2022-12-21 Sakata Holland B V Methods of sorting matthiola seeds
KR20240035997A (ko) 2021-06-16 2024-03-19 시드엑스 테크놀로지스 인코포레이티드 마티올라 종자들을 선별하는 방법들
CA3223344A1 (en) 2021-07-02 2023-01-05 Tropic Biosciences UK Limited Delay or prevention of browning in banana fruit
WO2023288046A1 (en) 2021-07-15 2023-01-19 President And Fellows Of Harvard College Compositions and methods relating to cells with adhered particles
KR20240046506A (ko) 2021-07-18 2024-04-09 가미다-셀 리미티드 치료용 nk세포 집단
WO2023002492A1 (en) 2021-07-22 2023-01-26 Yeda Research And Development Co. Ltd. Codon optimization of nucleic acids
CA3228014A1 (en) 2021-07-30 2023-02-16 Vib Vzm Cation-independent mannose-6-phosphate receptor binders for targeted protein degradation
WO2023012798A2 (en) 2021-08-02 2023-02-09 Yeda Research And Development Co. Ltd. Antibodies for the treatment of cancer
EP4130028A1 (en) 2021-08-03 2023-02-08 Rhazes Therapeutics Ltd Engineered tcr complex and methods of using same
JP2024536647A (ja) 2021-08-03 2024-10-07 ジェニシティー リミテッド 操作されたｔｃｒ複合体及びそれを使用する方法
CN118369418A (zh) 2021-08-10 2024-07-19 盖米达细胞有限公司 工程nk细胞、它们的生产方法及其用途
GB202112866D0 (en) 2021-09-09 2021-10-27 Tropic Biosciences Uk Ltd Resistance to fusarium wilt in a banana
GB202112865D0 (en) 2021-09-09 2021-10-27 Tropic Biosciences Uk Ltd Resistance to black sigatoka disease in banana
IL286430A (en) 2021-09-14 2023-04-01 Yeda Res & Dev Multispecific antibodies for use in the treatment of diseases
WO2023043280A1 (ko) 2021-09-17 2023-03-23 주식회사 씨젠 합성 비자연 염기를 포함하는 태그 올리고뉴클레오타이드를 이용한 타겟 핵산 서열의 검출
WO2023076857A1 (en) 2021-10-26 2023-05-04 Caribou Biosciences, Inc. Exonuclease-coupled real-time endonuclease activity assay
CN118339286A (zh) 2021-11-02 2024-07-12 马萨诸塞大学 Nme2Cas9镶嵌结构域融合蛋白
TW202440647A (zh) 2021-11-19 2024-10-16 英商米羅比奧有限公司 經工程改造之pd-1抗體及其用途
US11833503B2 (en) 2021-12-07 2023-12-05 Insilixa, Inc. Methods and compositions for surface functionalization of optical semiconductor-integrated biochips
KR20240128868A (ko) 2021-12-08 2024-08-27 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 폐 재생을 위한 다능성 폐 전구 세포
KR20240104144A (ko) 2021-12-10 2024-07-04 주식회사 씨젠 단일 가닥 상호작용적 이중 표지 시스템을 포함하는 태그된 루프프라이머 및 이를 이용한 핵산 등온 증폭 방법
AU2023210897A1 (en) 2022-01-25 2024-09-05 Medilink Therapeutics (Suzhou) Co., Ltd. Antibody against her3, conjugate and use thereof
GB202201137D0 (en) 2022-01-28 2022-03-16 Thelper As Therapeutic and diagnostic agents and uses thereof
CN118922401A (zh) 2022-01-31 2024-11-08 盖纳万科学有限公司 用于脂质纳米颗粒的可电离阳离子脂质
EP4238988A1 (en) 2022-03-01 2023-09-06 Consejo Superior De Investigaciones Científicas Antibodies against sars-cov-2 and uses thereof
EP4239338A1 (de) 2022-03-03 2023-09-06 Siemens Healthcare Diagnostics Products GmbH Globaltest zur feststellung des status des blutgerinnungssystems
CN114853890B (zh) 2022-03-16 2023-04-28 沈阳三生制药有限责任公司 一种prlr抗原结合蛋白及其制备方法和应用
JP2025512888A (ja) 2022-04-01 2025-04-22 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム ヒトｐｄ－ｌ１およびｐｄ－ｌ２に対する二重特異性抗体ならびにその使用方法
GB202204813D0 (en) 2022-04-01 2022-05-18 Bradcode Ltd Human monoclonal antibodies and methods of use thereof
US20230357851A1 (en) 2022-04-06 2023-11-09 Larimar Therapeutics, Inc. Frataxin-sensitive markers for monitoring frataxin-replacement therapy
IL315888A (en) 2022-04-06 2024-11-01 Mirobio Ltd Transgenic CD200R antibodies and their uses
WO2023209708A1 (en) 2022-04-25 2023-11-02 Yeda Research And Development Co. Ltd. Compositions for altering cyclic adp-ribose secondary messenger signalling
CN119744260A (zh) 2022-06-08 2025-04-01 恩库勒公司 作为pi3k抑制剂的苯并嘧啶-4(3h)-酮
WO2023240201A1 (en) 2022-06-08 2023-12-14 Larimar Therapeutics, Inc. Frataxin-sensitive markers for monitoring progression and treatment of leigh syndrome
IL317568A (en) 2022-06-10 2025-02-01 Res Found Dev Engineered FCRIIB Selective IgG1 FC Variants, and Their Uses
WO2023246701A1 (zh) 2022-06-20 2023-12-28 四川汇宇制药股份有限公司 一种抗体及其用途
KR20250034099A (ko) 2022-06-27 2025-03-10 주식회사 씨젠 베타-하이드록시산을 이용한 타겟 핵산의 증폭 방법
IL318217A (en) 2022-07-14 2025-03-01 Medilink Therapeutics Suzhou Co Ltd Antibody-drug conjugate, method for its preparation and use
WO2024028794A1 (en) 2022-08-02 2024-02-08 Temple Therapeutics BV Methods for treating endometrial and ovarian hyperproliferative disorders
WO2024040020A1 (en) 2022-08-15 2024-02-22 Absci Corporation Quantitative affinity activity specific cell enrichment
WO2024038160A1 (en) 2022-08-18 2024-02-22 Vib Vzw Means and methods to modulate neuron excitability
EP4325224A1 (de) 2022-08-18 2024-02-21 Siemens Healthcare Diagnostics Products GmbH Thrombozytenaktivierungstest zur diagnose einer heparin-induzierten thrombozytopenie
EP4584254A1 (en) 2022-09-08 2025-07-16 OnKure, Inc. Isoquinolones as pi3k inhibitors
WO2024064024A1 (en) 2022-09-19 2024-03-28 Onkure, Inc. ((4-oxo-3,4-dihydroquinazolin-8-yl)methyl)amine derivatives as p13k inhibitors for the treatment of cancer
KR20250068694A (ko) 2022-09-20 2025-05-16 온쿠레 인코포레이티드 Mapk 경로 돌연변이로 인한 암의 치료를 위한 hdac 억제제 oki-179
EP4594348A1 (en) 2022-09-27 2025-08-06 Vib Vzw Antivirals against human parainfluenza virus
KR20250086619A (ko) 2022-10-14 2025-06-13 주식회사 씨젠 상이한 tm 값을 가지는 2개의 프로브를 이용하여 샘플 내 타겟 핵산을 검출하는 방법
WO2024081345A1 (en) 2022-10-14 2024-04-18 Onkure, Inc. Benzopyrimidin-4(3h)-ones as pi3k inhibitors
CN120475986A (zh) 2022-11-11 2025-08-12 艾甘生物科学有限公司 IgA蛋白酶多肽剂
KR20250110818A (ko) 2022-11-16 2025-07-21 주식회사 씨젠 퀀칭-pto 절단 및 연장(quenching-pto cleavage and extension；q-ptoce) 어세이에 의한 타겟 핵산의 검출
WO2024124041A1 (en) 2022-12-07 2024-06-13 Advanced Cell Diagnostics, Inc. Multiplexed detection of nucleic acid targets
WO2024178172A1 (en) 2023-02-23 2024-08-29 University Of Rochester Agents and methods for making closed-end dna thread molecules
WO2024213648A1 (en) 2023-04-11 2024-10-17 Sterling Ip Pte. Ltd. Treatment of haematological cancer
TW202504637A (zh) 2023-06-13 2025-02-01 美商艾德森特克斯治療股份有限公司 與結合至nectin-4蛋白之抗體及抗體藥物結合物(adc)相關之方法及組合物
WO2024261344A1 (en) 2023-06-23 2024-12-26 Vib Vzw Novel binders targeting the multi-drug resistant pathogen acinetobacter baumannii
WO2025038395A1 (en) 2023-08-11 2025-02-20 Onkure, Inc. Benzopyridinones and benzopyrimidinones as pi3k inhibitors
WO2025052278A1 (en) 2023-09-05 2025-03-13 Genevant Sciences Gmbh Pyrrolidine based cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells
WO2025054524A1 (en) 2023-09-07 2025-03-13 University Of Tennessee Research Foundation Method for diagnosing amyloid diseases
WO2025125577A1 (en) 2023-12-14 2025-06-19 Vib Vzw Antibodies against influenza b virus
WO2025133951A1 (en) 2023-12-21 2025-06-26 Genevant Sciences Gmbh Ionizable lipids suitable for lipid nanoparticles
EP4585926A1 (de) 2024-01-09 2025-07-16 Siemens Healthcare Diagnostics Products GmbH Verfahren und kit zur reduzierung von interferenzen in immunoassays
WO2025150045A1 (en) 2024-01-12 2025-07-17 Gabriel Nussbaum Bacterial targets, therapeutics, compositions, kits and methods of use in treating and/or preventing cancer
WO2025155991A2 (en) 2024-01-19 2025-07-24 Bpgbio, Inc. Predictive biomarkers for response to coenzyme q10 treatment in pancreatic cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901654A (en) * 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3935074A (en) * 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies

Also Published As

Publication number Publication date
JPS5144628A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-04-16
NL185423C (nl) 1990-04-02
CH621873A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-02-27
ES440173A1 (es) 1977-03-01
IL47835A0 (en) 1975-10-15
FR2282115B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-08-21
DE2535574A1 (de) 1976-03-04
IL47835A (en) 1978-08-31
JPS6018940B2 (ja) 1985-05-13
AU501140B2 (en) 1979-06-14
GB1526242A (en) 1978-09-27
DE2535574C2 (de) 1986-01-16
SE427504B (sv) 1983-04-11
BR7505107A (pt) 1976-08-31
SE7509028L (sv) 1976-02-13
NL7509587A (nl) 1976-02-16
US3996345A (en) 1976-12-07
AU8388175A (en) 1977-02-17
FR2282115A1 (fr) 1976-03-12
SE7609841L (sv) 1977-03-09
GB1526241A (en) 1978-09-27
SE426746B (sv) 1983-02-07

Similar Documents

Publication Publication Date Title
CA1042792A (en) Fluorescence quenching with immunological pairs in immunoassays
US4261968A (en) Fluorescence quenching with immunological pairs in immunoassays
US4199559A (en) Fluorescence quenching with immunological pairs in immunoassays
US4174384A (en) Fluorescence quenching with immunological pairs in immunoassays
US4272506A (en) Purification of reagents by disulfide immobilization
US3998943A (en) Double receptor fluorescent immunoassay
US6251581B1 (en) Assay method utilizing induced luminescence
US4668640A (en) Fluorescence polarization immunoassay utilizing substituted carboxyfluoresceins
CA1111763A (en) Lipophilic particles non-covalently bonded to label and ligand for binding assay
US5391740A (en) Fluoresence polarization immunoassay
US4160016A (en) Receptor fluorescent immunoassay
US4161515A (en) Double receptor fluorescent immunoassay
EP0668504B1 (en) Quaternary ammonium immunogenic conjugates and immunoassay reagent
US5340716A (en) Assay method utilizing photoactivated chemiluminescent label
EP0984282B1 (en) Particles having an incorporated composition comprising a chemiluminescent compound
US5994143A (en) Polymeric fluorophores enhanced by moieties providing a hydrophobic and conformationally restrictive microenvironment
US4218539A (en) Enzyme conjugates and method of preparation and use
US4510251A (en) Fluorescent polarization assay for ligands using aminomethylfluorescein derivatives as tracers
US4255329A (en) Double receptor fluorescent immunoassay
GB2111476A (en) Substituted carboxy- fluoresceins and their use in fluorescence polarization immunoassay
JPH034596B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
US5661040A (en) Fluorescent polymer labeled conjugates and intermediates
US4261974A (en) Valproic acid immunogen conjugates and antibodies thereto
CH648414A5 (de) Antienzym-homogen-kompetitivbindungs-test.
US6476199B1 (en) Reagents for lysergic acid diethylamide immunoassay