AU2002220275A1 - Mutated class ii major histocompatibility proteins - Google Patents

Mutated class ii major histocompatibility proteins

Info

Publication number
AU2002220275A1
AU2002220275A1 AU2002220275A AU2027502A AU2002220275A1 AU 2002220275 A1 AU2002220275 A1 AU 2002220275A1 AU 2002220275 A AU2002220275 A AU 2002220275A AU 2027502 A AU2027502 A AU 2027502A AU 2002220275 A1 AU2002220275 A1 AU 2002220275A1
Authority
AU
Australia
Prior art keywords
major histocompatibility
histocompatibility proteins
mutated class
mutated
class
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002220275A
Inventor
Jeffrey A Bluestone
David M. Kranz
Scott Starwalt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Illinois
Original Assignee
University of Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Illinois filed Critical University of Illinois
Publication of AU2002220275A1 publication Critical patent/AU2002220275A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
AU2002220275A 2000-12-08 2001-12-10 Mutated class ii major histocompatibility proteins Abandoned AU2002220275A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25424800P 2000-12-08 2000-12-08
US60/254,248 2000-12-08
PCT/US2001/047830 WO2002046400A2 (en) 2000-12-08 2001-12-10 Mutated class ii major histocompatibility proteins

Publications (1)

Publication Number Publication Date
AU2002220275A1 true AU2002220275A1 (en) 2002-06-18

Family

ID=22963520

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002220275A Abandoned AU2002220275A1 (en) 2000-12-08 2001-12-10 Mutated class ii major histocompatibility proteins

Country Status (3)

Country Link
US (1) US20020165149A1 (en)
AU (1) AU2002220275A1 (en)
WO (1) WO2002046400A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1438400B1 (en) 2001-10-01 2009-06-17 Dyax Corp. Multi-chain eukaryotic display vectors and uses thereof
ATE386810T1 (en) * 2002-06-14 2008-03-15 Dyax Corp RECOMBINATION OF NUCLEIC ACID LIBRARY MEMBERS
EP1932916A1 (en) * 2002-06-14 2008-06-18 Dyax Corporation Methods involving recombination of nucleic acid library members
JP4748984B2 (en) * 2002-06-16 2011-08-17 ダイアックス、コープ Recombination of nucleic acid library members
US7442773B2 (en) * 2004-01-23 2008-10-28 The Board Of Trustees Of The University Of Illinois Universal peptide-binding scaffolds and protein chips
US10816554B2 (en) 2014-04-04 2020-10-27 The Board Of Trustees Of The Leland Stanford Junior University Ligand discovery for T cell receptors
CA2955984A1 (en) 2014-07-22 2016-01-28 The University Of Notre Dame Du Lac Molecular constructs and uses thereof
SG11202109073VA (en) 2019-02-20 2021-09-29 Rubius Therapeutics Inc Engineered erythroid cells including loadable antigen-presenting polypeptides and methods of use
WO2023066932A1 (en) * 2021-10-18 2023-04-27 Immatics Biotechnologies Gmbh Stabilized mhc molecules

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (en) * 1970-11-10 1977-09-15 Organon Nv PROCEDURE FOR DETERMINING AND DETERMINING LOW MOLECULAR COMPOUNDS AND PROTEINS THAT CAN SPECIFICALLY BIND THESE COMPOUNDS AND TEST PACKAGING.
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3927193A (en) * 1973-05-18 1975-12-16 Hoffmann La Roche Localization of tumors by radiolabelled antibodies
US3939350A (en) * 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) * 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) * 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) * 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4444744A (en) * 1980-03-03 1984-04-24 Goldenberg Milton David Tumor localization and therapy with labeled antibodies to cell surface antigens
US4331647A (en) * 1980-03-03 1982-05-25 Goldenberg Milton David Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
US4361544A (en) * 1980-03-03 1982-11-30 Goldenberg Milton David Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers
US4348376A (en) * 1980-03-03 1982-09-07 Goldenberg Milton David Tumor localization and therapy with labeled anti-CEA antibody
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4468457A (en) * 1981-06-01 1984-08-28 David M. Goldenberg Method for producing a CSAp tryptic peptide and anti-CSAp antibodies
US4713332A (en) * 1984-01-13 1987-12-15 The Ontario Cancer Institute T cell specific CDNA clone
US4923799A (en) * 1984-02-06 1990-05-08 The Ontario Cancer Institute T cell specific cDNA clone
US4970296A (en) * 1984-03-01 1990-11-13 Massachusetts Institute Of Technology Heterodimeric T lymphocyte receptor
US4874845A (en) * 1984-06-13 1989-10-17 Massachusetts Institute Of Technology T lymphocyte receptor subunit
WO1985003947A1 (en) * 1984-03-01 1985-09-12 The Board Of Trustees Of The Leland Stanford Jr. U T-cell receptor-specific for antigen polypeptides and related polynucleotides
US4873190A (en) * 1984-06-13 1989-10-10 Massachusetts Institute Of Technology Heterodimeric T lymphocyte receptor
US5411873A (en) * 1984-05-29 1995-05-02 Genencor, Inc. Process for producing heterologous polypeptides
US5977321A (en) * 1984-06-13 1999-11-02 Massachusetts Institute Of Technology Heterodimeric T lymphocyte receptor subunit
US5189147A (en) * 1984-06-13 1993-02-23 Massachusetts Institute Of Technology Meterodimeric T lymphocyte receptor antibody
US6492107B1 (en) * 1986-11-20 2002-12-10 Stuart Kauffman Process for obtaining DNA, RNA, peptides, polypeptides, or protein, by recombinant DNA technique
EP0229046B1 (en) * 1985-03-30 1994-05-04 BALLIVET, Marc Method for obtaining dna, rna, peptides, polypeptides or proteins by means of a dna recombinant technique
US5101827A (en) * 1985-07-05 1992-04-07 Immunomedics, Inc. Lymphographic and organ imaging method and kit
US5013650A (en) * 1985-08-02 1991-05-07 Merck & Co., Inc. Increased fermentation yield of expressed protein
US4640561A (en) * 1985-11-15 1987-02-03 Ford Motor Company Flexible printed circuit connector
US4831122A (en) * 1986-01-09 1989-05-16 Regents Of The University Of Minnesota Radioimmunotoxins
US5225539A (en) * 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5900476A (en) * 1986-05-30 1999-05-04 The Scripps Research Institute Therapeutic domains of van Willebrand factor
US5185250A (en) * 1986-07-03 1993-02-09 T Cell Sciences, Inc. Human γ, δT cell antigen receptor polypeptides and nucleic acids
US5024940A (en) * 1987-02-19 1991-06-18 T Cell Sciences, Inc. Nucleic acids encoding the delta chain of the T cell antigen receptor
US5340921A (en) * 1986-07-03 1994-08-23 T Cell Sciences, Inc. Γ, δT cell receptor and methods and detection
US5869620A (en) * 1986-09-02 1999-02-09 Enzon, Inc. Multivalent antigen-binding proteins
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5260203A (en) * 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US5258498A (en) * 1987-05-21 1993-11-02 Creative Biomolecules, Inc. Polypeptide linkers for production of biosynthetic proteins
US5059413A (en) * 1988-04-18 1991-10-22 Xoma Corporation Scintigraphic monitoring of immunotoxins using radionuclides and heterobifunctional chelators
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5614192A (en) * 1989-07-19 1997-03-25 Connective Therapeutics, Inc. T cell receptor peptides as therapeutics for immune-related disease
US5427908A (en) * 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
US5723286A (en) * 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
GB9015198D0 (en) * 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5258289A (en) * 1990-09-05 1993-11-02 Davis Claude G Method for the selecting of genes encoding catalytic antibodies
US5871974A (en) * 1990-09-28 1999-02-16 Ixsys Inc. Surface expression libraries of heteromeric receptors
DE69230142T2 (en) * 1991-05-15 2000-03-09 Cambridge Antibody Tech METHOD FOR PRODUCING SPECIFIC BINDING PAIRS
US5858657A (en) * 1992-05-15 1999-01-12 Medical Research Council Methods for producing members of specific binding pairs
US5317097A (en) * 1991-10-07 1994-05-31 The Research Foundation Of State University Of New York Mutations in the gene encoding the α chain on platelet glycoprotein IB
US5866344A (en) * 1991-11-15 1999-02-02 Board Of Regents, The University Of Texas System Antibody selection methods using cell surface expressed libraries
US5348867A (en) * 1991-11-15 1994-09-20 George Georgiou Expression of proteins on bacterial surface
US5733743A (en) * 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
US5299253A (en) * 1992-04-10 1994-03-29 Akzo N.V. Alignment system to overlay abdominal computer aided tomography and magnetic resonance anatomy with single photon emission tomography
US5316922A (en) * 1992-04-15 1994-05-31 The United States Of America As Represented By Department Of Health And Human Services Method for indentifying and expressing proteins that recognize and adhere to specific probes
ES2196009T3 (en) * 1992-07-08 2003-12-16 Unilever Nv PROCEDURE FOR IMMOBILIZING ENZYMES IN THE CELL WALL OF A MICROBIAL CELL BY MEANS OF THE PRODUCTION OF A FUSION PROTEIN.
FR2698880B1 (en) * 1992-11-25 1995-02-24 Inst Nat Sante Rech Med Process for the production of soluble T receptors, products thus obtained and their use in diagnostic or therapeutic compositions.
US5861156A (en) * 1993-01-08 1999-01-19 Creative Biomolecules Methods of delivering agents to target cells
US5837477A (en) * 1993-01-15 1998-11-17 The United States Of America As Represented By The Department Of Health And Human Services T cell receptor ligands and methods of using same
PT682710E (en) * 1993-02-10 2004-03-31 Unilever Nv ISOLATION PROCESS USING PROPRIETARY PROTEINS WITH SPECIFIC LIGACATION CAPACITIES
GB9313509D0 (en) * 1993-06-30 1993-08-11 Medical Res Council Chemisynthetic libraries
DK0744958T3 (en) * 1994-01-31 2003-10-20 Univ Boston Polyclonal antibody libraries
US5824483A (en) * 1994-05-18 1998-10-20 Pence Inc. Conformationally-restricted combinatiorial library composition and method
US5989808A (en) * 1994-06-14 1999-11-23 American Cyanamid Company Identification of compounds affecting specific interaction of peptide binding pairs
US5763733A (en) * 1994-10-13 1998-06-09 Enzon, Inc. Antigen-binding fusion proteins
US5780255A (en) * 1995-06-09 1998-07-14 Instrumentation Laboratory, S.P.A. Protein C pathway screening test
US6300062B1 (en) * 1995-07-13 2001-10-09 Biora Ab Enamel matrix related polypeptide
US6300065B1 (en) * 1996-05-31 2001-10-09 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
US6232445B1 (en) * 1997-10-29 2001-05-15 Sunol Molecular Corporation Soluble MHC complexes and methods of use thereof
FR2778669B1 (en) * 1998-05-14 2002-06-14 Centre Nat Rech Scient PROCESS FOR EXPRESSING A COMPLEX FORMED OF AT LEAST ONE PRODUCT OF THE MAJOR HISTOCOMPATIBILITY COMPLEX AND A PEPTIDE IN A PHAGE, PHAGES AND COMPLEXES OBTAINED THEREFROM AND THEIR APPLICATIONS
DK1247095T3 (en) * 1999-12-06 2008-12-08 Univ Illinois High affinity TCR proteins and methods
AU2002227362A1 (en) * 2000-12-08 2002-06-18 The Board Of Trustees Of The University Of Illinois Mutated class i major histocompatibility proteins and complexes

Also Published As

Publication number Publication date
WO2002046400A2 (en) 2002-06-13
WO2002046400A3 (en) 2003-01-23
US20020165149A1 (en) 2002-11-07

Similar Documents

Publication Publication Date Title
AU2001232799A1 (en) Protein c derivatives
AU2001294192A1 (en) Solid preparations
AU6045900A (en) Interaction-activated proteins
AU2001239773A1 (en) Baroplastic materials
AU2002220275A1 (en) Mutated class ii major histocompatibility proteins
AU2002225749A1 (en) Powered periotome
AU2002305903A1 (en) Carbohydrate-associated proteins
AU2002232707A1 (en) Transmembrane proteins
AU2001259450A1 (en) Cytoskeleton-associated proteins
AU2002227362A1 (en) Mutated class i major histocompatibility proteins and complexes
AU2001266176A1 (en) Methods
AU2001288102A1 (en) Solid preparations
AU2002216100A1 (en) Dormancy - induced mycobacterium proteins
AU2001274676A1 (en) Plant-signalling ligand like proteins
AU2001272427A1 (en) Solid preparations
AU1881200A (en) Novel proteins
AU2002239747A1 (en) Cystoskeleton-associated proteins
AU2001244863A1 (en) Apoptin-associating protein
AU2001260633A1 (en) Fas ligand-fused proteins
AU2001250536A1 (en) Methods
AU2001262589A1 (en) Glycosyltransferase proteins
AU2002243234A1 (en) Embryogenesis associated proteins
AU2002224379A1 (en) Clasp-2 transmembrane proteins
AU2001241044A1 (en) Mitf-associated proteins
AU2001278777A1 (en) Irap-binding protein