IL250479A0 - Isolated cells genetically modified to express a disarm system having an anti-phage activity and methods of producing same - Google Patents

Isolated cells genetically modified to express a disarm system having an anti-phage activity and methods of producing same

Info

Publication number
IL250479A0
IL250479A0 IL250479A IL25047917A IL250479A0 IL 250479 A0 IL250479 A0 IL 250479A0 IL 250479 A IL250479 A IL 250479A IL 25047917 A IL25047917 A IL 25047917A IL 250479 A0 IL250479 A0 IL 250479A0
Authority
IL
Israel
Prior art keywords
express
methods
genetically modified
isolated cells
producing same
Prior art date
Application number
IL250479A
Other languages
Hebrew (he)
Inventor
Sorek Rotem
Sberro Hila
OFIR Gal
Melamed Sarah
Original Assignee
Sorek Rotem
Sberro Hila
OFIR Gal
Melamed Sarah
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sorek Rotem, Sberro Hila, OFIR Gal, Melamed Sarah, Yeda Res & Dev filed Critical Sorek Rotem
Priority to IL250479A priority Critical patent/IL250479A0/en
Publication of IL250479A0 publication Critical patent/IL250479A0/en
Priority to PCT/IL2018/050134 priority patent/WO2018142416A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
    • C12Y306/04—Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
    • C12Y306/04013—RNA helicase (3.6.4.13)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y201/00—Transferases transferring one-carbon groups (2.1)
    • C12Y201/01—Methyltransferases (2.1.1)
    • C12Y201/01037—DNA (cytosine-5-)-methyltransferase (2.1.1.37)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
    • C12Y306/04—Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
    • C12Y306/04012—DNA helicase (3.6.4.12)
IL250479A 2017-02-06 2017-02-06 Isolated cells genetically modified to express a disarm system having an anti-phage activity and methods of producing same IL250479A0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL250479A IL250479A0 (en) 2017-02-06 2017-02-06 Isolated cells genetically modified to express a disarm system having an anti-phage activity and methods of producing same
PCT/IL2018/050134 WO2018142416A1 (en) 2017-02-06 2018-02-06 Isolated cells genetically modified to express a disarm system having an anti-phage activity and methods of producing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL250479A IL250479A0 (en) 2017-02-06 2017-02-06 Isolated cells genetically modified to express a disarm system having an anti-phage activity and methods of producing same

Publications (1)

Publication Number Publication Date
IL250479A0 true IL250479A0 (en) 2017-03-30

Family

ID=61231294

Family Applications (1)

Application Number Title Priority Date Filing Date
IL250479A IL250479A0 (en) 2017-02-06 2017-02-06 Isolated cells genetically modified to express a disarm system having an anti-phage activity and methods of producing same

Country Status (2)

Country Link
IL (1) IL250479A0 (en)
WO (1) WO2018142416A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3060656A1 (en) 2013-10-24 2016-08-31 Yeda Research and Development Co., Ltd. Polynucleotides encoding brex system polypeptides and methods of using same
WO2018220616A2 (en) * 2017-05-30 2018-12-06 Yeda Research And Development Co. Ltd. Genetic systems that defend against foreign dna and uses thereof
NL2022928B1 (en) * 2018-11-13 2020-05-20 Univ Delft Tech Method for the generation of a non-CRISPR-Cas-mediated bacteriophage insensitive mutant using an anti-CRISPR protein.
WO2020101486A1 (en) * 2018-11-13 2020-05-22 Technische Universiteit Delft Method for the generation of a non-crispr bacteriophage insensitive mutant using an anti-crispr protein
MX2021014351A (en) * 2019-05-29 2022-01-06 Chr Hansen As Composition comprising biofilm forming bacillus.
CN111593000B (en) * 2020-05-18 2022-07-22 西北农林科技大学 Klebsiella for degrading plastic mulching film and application thereof
WO2023275328A1 (en) * 2021-07-02 2023-01-05 Ecole Polytechnique Federale De Lausanne (Epfl) Recombinant bacteria resistant to horizontal gene transfer and phage infection
IL288680A (en) * 2021-12-05 2023-07-01 Yeda Res & Dev Genetically modified phages and uses thereof

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Also Published As

Publication number Publication date
WO2018142416A1 (en) 2018-08-09

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