IL250479A0 - תאים מהונדסים גנטית המבטאים מערכת disarm המקנה עמידות לפאג'ים ושיטות לייצור שלהם - Google Patents

תאים מהונדסים גנטית המבטאים מערכת disarm המקנה עמידות לפאג'ים ושיטות לייצור שלהם

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Publication number
IL250479A0
IL250479A0 IL250479A IL25047917A IL250479A0 IL 250479 A0 IL250479 A0 IL 250479A0 IL 250479 A IL250479 A IL 250479A IL 25047917 A IL25047917 A IL 25047917A IL 250479 A0 IL250479 A0 IL 250479A0
Authority
IL
Israel
Prior art keywords
express
methods
genetically modified
isolated cells
producing same
Prior art date
Application number
IL250479A
Other languages
English (en)
Inventor
Sorek Rotem
Sberro Hila
OFIR Gal
Melamed Sarah
Original Assignee
Sorek Rotem
Sberro Hila
OFIR Gal
Melamed Sarah
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sorek Rotem, Sberro Hila, OFIR Gal, Melamed Sarah, Yeda Res & Dev filed Critical Sorek Rotem
Priority to IL250479A priority Critical patent/IL250479A0/he
Publication of IL250479A0 publication Critical patent/IL250479A0/he
Priority to PCT/IL2018/050134 priority patent/WO2018142416A1/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y306/00Hydrolases acting on acid anhydrides (3.6)
    • C12Y306/04Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
    • C12Y306/04013RNA helicase (3.6.4.13)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1003Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007Methyltransferases (general) (2.1.1.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y201/00Transferases transferring one-carbon groups (2.1)
    • C12Y201/01Methyltransferases (2.1.1)
    • C12Y201/01037DNA (cytosine-5-)-methyltransferase (2.1.1.37)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y306/00Hydrolases acting on acid anhydrides (3.6)
    • C12Y306/04Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
    • C12Y306/04012DNA helicase (3.6.4.12)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL250479A 2017-02-06 2017-02-06 תאים מהונדסים גנטית המבטאים מערכת disarm המקנה עמידות לפאג'ים ושיטות לייצור שלהם IL250479A0 (he)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL250479A IL250479A0 (he) 2017-02-06 2017-02-06 תאים מהונדסים גנטית המבטאים מערכת disarm המקנה עמידות לפאג'ים ושיטות לייצור שלהם
PCT/IL2018/050134 WO2018142416A1 (en) 2017-02-06 2018-02-06 Isolated cells genetically modified to express a disarm system having an anti-phage activity and methods of producing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL250479A IL250479A0 (he) 2017-02-06 2017-02-06 תאים מהונדסים גנטית המבטאים מערכת disarm המקנה עמידות לפאג'ים ושיטות לייצור שלהם

Publications (1)

Publication Number Publication Date
IL250479A0 true IL250479A0 (he) 2017-03-30

Family

ID=61231294

Family Applications (1)

Application Number Title Priority Date Filing Date
IL250479A IL250479A0 (he) 2017-02-06 2017-02-06 תאים מהונדסים גנטית המבטאים מערכת disarm המקנה עמידות לפאג'ים ושיטות לייצור שלהם

Country Status (2)

Country Link
IL (1) IL250479A0 (he)
WO (1) WO2018142416A1 (he)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015059690A1 (en) 2013-10-24 2015-04-30 Yeda Research And Development Co. Ltd. Polynucleotides encoding brex system polypeptides and methods of using s ame
US20200109395A1 (en) * 2017-05-30 2020-04-09 Yeda Research And Development Co. Ltd. Genetic systems that defend against foreign dna and uses thereof
WO2020101486A1 (en) * 2018-11-13 2020-05-22 Technische Universiteit Delft Method for the generation of a non-crispr bacteriophage insensitive mutant using an anti-crispr protein
NL2022928B1 (en) * 2018-11-13 2020-05-20 Univ Delft Tech Method for the generation of a non-CRISPR-Cas-mediated bacteriophage insensitive mutant using an anti-CRISPR protein.
AR119025A1 (es) * 2019-05-29 2021-11-17 Chr Hansen As Composición que comprende un bacillus formador de biopelícula
CN111593000B (zh) * 2020-05-18 2022-07-22 西北农林科技大学 一株降解塑料地膜的克雷伯氏菌及其应用
WO2023275328A1 (en) * 2021-07-02 2023-01-05 Ecole Polytechnique Federale De Lausanne (Epfl) Recombinant bacteria resistant to horizontal gene transfer and phage infection
IL288680A (he) 2021-12-05 2023-07-01 Yeda Res & Dev פאג'ים מהונדסים גנטית והשימוש בהם
GB202303034D0 (en) * 2023-03-01 2023-04-12 Univ Exeter Bacterial defence system

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