SI1487972T1 - Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe - Google Patents

Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe

Info

Publication number
SI1487972T1
SI1487972T1 SI200332453T SI200332453T SI1487972T1 SI 1487972 T1 SI1487972 T1 SI 1487972T1 SI 200332453 T SI200332453 T SI 200332453T SI 200332453 T SI200332453 T SI 200332453T SI 1487972 T1 SI1487972 T1 SI 1487972T1
Authority
SI
Slovenia
Prior art keywords
methods
monoclonal antibodies
deficient mice
specific monoclonal
antibodies generated
Prior art date
Application number
SI200332453T
Other languages
English (en)
Inventor
Jaromir Pastorek
Silvia Pastorekova
Miriam Zatovicova
Jan Zavada
Gut Marta Ortova
Zuzanna Zavadova
Original Assignee
Institute Of Virology Slovak Academy Of Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute Of Virology Slovak Academy Of Sciences filed Critical Institute Of Virology Slovak Academy Of Sciences
Priority claimed from PCT/US2003/005136 external-priority patent/WO2003100029A2/en
Priority claimed from EP03713562.1A external-priority patent/EP1487972B1/en
Publication of SI1487972T1 publication Critical patent/SI1487972T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B3/00—Measuring instruments characterised by the use of mechanical techniques
    • G01B3/10—Measuring tapes
    • G01B3/1084—Tapes combined with arrangements for functions other than measuring lengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B3/00—Measuring instruments characterised by the use of mechanical techniques
    • G01B3/10—Measuring tapes
    • G01B3/1084—Tapes combined with arrangements for functions other than measuring lengths
    • G01B3/1089—Tapes combined with arrangements for functions other than measuring lengths for marking, drawing or cutting
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B3/00—Measuring instruments characterised by the use of mechanical techniques
    • G01B3/10—Measuring tapes
    • G01B3/1061—Means for displaying or assisting reading of length measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/82—Translation products from oncogenes
SI200332453T 2002-02-21 2003-02-21 Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe SI1487972T1 (sl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US35882402P 2002-02-21 2002-02-21
US38306802P 2002-05-23 2002-05-23
US43149902P 2002-12-05 2002-12-05
PCT/US2003/005136 WO2003100029A2 (en) 2002-02-21 2003-02-21 Mn/ca ix-specific monoclonal antibodies generated from mn/ca ix-deficient mice and methods of use
EP03713562.1A EP1487972B1 (en) 2002-02-21 2003-02-21 Mn/ca ix-specific monoclonal antibodies generated from mn/ca ix-deficient mice and methods of use

Publications (1)

Publication Number Publication Date
SI1487972T1 true SI1487972T1 (sl) 2016-03-31

Family

ID=27737296

Family Applications (3)

Application Number Title Priority Date Filing Date
SI200332452T SI2508596T1 (sl) 2002-02-21 2003-02-21 Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe
SI200332453T SI1487972T1 (sl) 2002-02-21 2003-02-21 Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe
SI200332554T SI3031910T1 (sl) 2002-02-21 2003-02-21 Mn/ca ix-specifična monoklonska protitelesa generirana iz mn/ca- pomanjkljive miši in metode uporabe

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200332452T SI2508596T1 (sl) 2002-02-21 2003-02-21 Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200332554T SI3031910T1 (sl) 2002-02-21 2003-02-21 Mn/ca ix-specifična monoklonska protitelesa generirana iz mn/ca- pomanjkljive miši in metode uporabe

Country Status (4)

Country Link
EP (2) EP2508596B1 (sl)
CA (1) CA2704273C (sl)
DK (1) DK2508596T3 (sl)
SI (3) SI2508596T1 (sl)

Family Cites Families (33)

* Cited by examiner, † Cited by third party
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NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3766162A (en) 1971-08-24 1973-10-16 Hoffmann La Roche Barbituric acid antigens and antibodies specific therefor
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4233402A (en) 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
IL63224A (en) 1980-07-17 1985-05-31 Scripps Clinic Res Synthetic peptide specific antigenic determinant and method of manufacturing antigenic materials therefrom
DE3208890A1 (de) 1981-04-22 1982-12-16 Chemische Fabrik Grünau GmbH, 7918 Illertissen Feuerschutz-ummantelung
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5401638A (en) 1986-06-04 1995-03-28 Oncogene Science, Inc. Detection and quantification of neu related proteins in the biological fluids of humans
ES2070172T3 (es) 1988-04-16 1995-06-01 Celltech Ltd Procedimiento para producir proteinas mediante adn recombinante.
ES2052027T5 (es) 1988-11-11 2005-04-16 Medical Research Council Clonacion de secuencias de dominio variable de inmunoglobulina.
CA2016842A1 (en) 1989-05-16 1990-11-16 Richard A. Lerner Method for tapping the immunological repertoire
CA2016841C (en) 1989-05-16 1999-09-21 William D. Huse A method for producing polymers having a preselected activity
KR100282284B1 (ko) 1992-03-11 2001-02-15 유르데 미키 Mn 유전자 및 단백질
US5387676A (en) 1992-03-11 1995-02-07 Ciba Corning Diagnostics Corp. MN gene and protein
US5981711A (en) 1992-03-11 1999-11-09 Institute Of Virology, Slovak Academy Of Sciences MN-specific antibodies and hybridomas
US5989838A (en) 1992-03-11 1999-11-23 Institute Of Virology, Slovak Academy Of Sciences Immunological methods of detecting MN proteins and MN polypeptides
US6297041B1 (en) 1992-03-11 2001-10-02 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US5955075A (en) 1992-03-11 1999-09-21 Institute Of Virology, Slovak Academy Of Sciences Method of inhibiting tumor growth using antibodies to MN protein
US5972353A (en) 1992-03-11 1999-10-26 Institute Of Virology, Slovak Academy Of Sciences MN proteins, polypeptides, fusion proteins and fusion polypeptides
US6297051B1 (en) 1997-01-24 2001-10-02 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US6204370B1 (en) 1992-03-11 2001-03-20 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US6069242A (en) 1992-03-11 2000-05-30 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US6093548A (en) 1992-03-11 2000-07-25 Institute Of Virology, Slovak Academy Of Sciences Detection and quantitation of MN-specific antibodies.
US5363394A (en) 1993-08-06 1994-11-08 At&T Bell Laboratories Quantum wire laser
AU2861695A (en) 1994-06-15 1996-01-05 Ciba Corning Diagnostics Corp. Mn gene and protein
DK1123387T3 (da) 1998-10-23 2008-02-25 Inst Virology MN-gen og protein
US6204887B1 (en) 1998-12-11 2001-03-20 Hitachi America, Ltd. Methods and apparatus for decoding and displaying multiple images using a common processor
EP1487972B1 (en) * 2002-02-21 2015-08-12 Institute Of Virology Mn/ca ix-specific monoclonal antibodies generated from mn/ca ix-deficient mice and methods of use

Also Published As

Publication number Publication date
CA2704273C (en) 2016-01-05
EP2508596A3 (en) 2013-04-24
SI2508596T1 (sl) 2016-01-29
SI3031910T1 (sl) 2018-05-31
EP2508596A2 (en) 2012-10-10
EP3031910B1 (en) 2017-08-16
EP3031910A1 (en) 2016-06-15
CA2704273A1 (en) 2003-12-04
DK2508596T3 (en) 2015-10-19
EP2508596B1 (en) 2015-08-12

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SI1487972T1 (sl) Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe