HUP0300810A2 - Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazása - Google Patents
Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazásaInfo
- Publication number
- HUP0300810A2 HUP0300810A2 HU0300810A HUP0300810A HUP0300810A2 HU P0300810 A2 HUP0300810 A2 HU P0300810A2 HU 0300810 A HU0300810 A HU 0300810A HU P0300810 A HUP0300810 A HU P0300810A HU P0300810 A2 HUP0300810 A2 HU P0300810A2
- Authority
- HU
- Hungary
- Prior art keywords
- artifical
- producing
- methods
- same
- vascular grafts
- Prior art date
Links
- 230000002792 vascular Effects 0.000 title abstract 3
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 210000002889 endothelial cell Anatomy 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3808—Endothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3826—Muscle cells, e.g. smooth muscle cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Abstract
A jelen találmány mesterséges ér transzplantátumot, valamint ennek azelőállítására szolgáló módszert biztosít. A mesterséges értranszplantátum egy olyan szintetikus tubuláris elem, melyendoteliális sejtek és/vagy simaizom sejtek sokaságával burkoltluminális felszínnel rendelkezik, az említett sejteket genetikailagúgy transzformáltuk, hogy legalább egy sejt proliferációs növekedésifaktort és legalább egy celluláris tapadási faktort expresszáljanak. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62022700A | 2000-07-20 | 2000-07-20 | |
PCT/IL2001/000670 WO2002007646A2 (en) | 2000-07-20 | 2001-07-20 | Artificial vascular grafts, and methods of producing and using same |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP0300810A2 true HUP0300810A2 (hu) | 2003-08-28 |
Family
ID=24485086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0300810A HUP0300810A2 (hu) | 2000-07-20 | 2000-07-20 | Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazása |
Country Status (13)
Country | Link |
---|---|
US (4) | US7364725B1 (hu) |
EP (1) | EP1301146B1 (hu) |
JP (1) | JP5067822B2 (hu) |
AT (1) | ATE469615T1 (hu) |
AU (1) | AU2001278664A1 (hu) |
CA (1) | CA2416548A1 (hu) |
CZ (1) | CZ2003253A3 (hu) |
DE (1) | DE60142290D1 (hu) |
HU (1) | HUP0300810A2 (hu) |
IL (1) | IL153946A0 (hu) |
PL (1) | PL362561A1 (hu) |
WO (1) | WO2002007646A2 (hu) |
ZA (1) | ZA200300635B (hu) |
Families Citing this family (28)
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US6485723B1 (en) | 1995-02-10 | 2002-11-26 | Purdue Research Foundation | Enhanced submucosal tissue graft constructs |
KR100860860B1 (ko) * | 2000-03-15 | 2008-09-29 | 오르버스네이치 메디칼 인코포레이티드 | 내피 세포 부착을 촉진하는 코팅 |
US7175658B1 (en) | 2000-07-20 | 2007-02-13 | Multi-Gene Vascular Systems Ltd. | Artificial vascular grafts, their construction and use |
HUP0300810A2 (hu) | 2000-07-20 | 2003-08-28 | M.G.V.S. Ltd. | Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazása |
AU2003211066A1 (en) * | 2002-02-19 | 2003-09-09 | Bioarttis, Inc. | Artificial vessel scaffold and artificial organs therefrom |
AU2003231209B2 (en) * | 2002-05-02 | 2009-08-06 | Cook Biotech Incorporated | Cell-seeded extracellular matrix grafts |
AU2003243184C1 (en) | 2002-05-02 | 2009-04-09 | Purdue Research Foundation | Vascularization enhanced graft constructs |
CA2483683C (en) | 2002-05-02 | 2013-07-02 | Purdue Research Foundation | Vascularization enhanced graft constructs |
CN1713861A (zh) | 2002-05-02 | 2005-12-28 | 普渡研究基金会 | 血管化增强的移植构造物 |
KR20070008714A (ko) | 2004-04-30 | 2007-01-17 | 오르버스네이치 메디칼 인코포레이티드 | 유전적으로-변형된 세포 포획용 코팅을 갖는 의료 장치 및이의 사용 방법 |
WO2006017275A1 (en) | 2004-07-13 | 2006-02-16 | The University Of Tennessee Research Foundation | Adhesive composition for carrying therapeutic agents as delivery vehicle on coatings applied to vascular grafts |
CA2637662A1 (en) * | 2006-01-31 | 2007-08-09 | Multi-Gene Vascular Systems, Inc. | Drug-eluting intravascular prostheses and methods of use |
JP5839814B2 (ja) * | 2010-03-17 | 2016-01-06 | グンゼ株式会社 | Danceタンパク質含有徐放基材及び該徐放基材の製造方法 |
EP2575913B1 (en) | 2010-05-25 | 2018-07-25 | Cook Biotech Incorporated | Methods, substrates, and systems useful for cell seeding of medical grafts |
US20140065110A1 (en) | 2012-08-31 | 2014-03-06 | The Regents Of The University Of California | Genetically modified msc and therapeutic methods |
US9663564B2 (en) | 2013-03-15 | 2017-05-30 | The Regents Of The University Of California | Vectors and methods to treat ischemia |
WO2014070792A1 (en) | 2012-10-29 | 2014-05-08 | Ariste Medical, Inc. | Polymer coating compositions and coated products |
US9878071B2 (en) | 2013-10-16 | 2018-01-30 | Purdue Research Foundation | Collagen compositions and methods of use |
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JP2017537934A (ja) * | 2014-12-07 | 2017-12-21 | ヴェッスル セラピューティクス リミテッド | ケロイド瘢痕を処置するためのフィビュリン−5の使用 |
WO2016140716A1 (en) | 2015-03-02 | 2016-09-09 | The Trustees Of Columbia University In The City Of New York | Injectable microtissue systems, devices, and methods |
WO2016172365A1 (en) | 2015-04-21 | 2016-10-27 | Purdue Research Foundation Office Of Technology Commercialization | Cell-collagen-silica composites and methods of making and using the same |
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CN106075585B (zh) * | 2016-07-08 | 2019-06-21 | 福建师范大学 | 一种基于人工肌腱支架材料的组织工程化人工肌腱移植物的制备方法 |
US11439731B2 (en) | 2016-09-14 | 2022-09-13 | Revotek Co., Ltd. | Artificial tissue progenitor and method for preparing the same |
CN110229779A (zh) * | 2016-09-14 | 2019-09-13 | 四川蓝光英诺生物科技股份有限公司 | 人工组织前体及制备其的方法 |
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HUP0300810A2 (hu) | 2000-07-20 | 2003-08-28 | M.G.V.S. Ltd. | Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazása |
US6939376B2 (en) | 2001-11-05 | 2005-09-06 | Sun Biomedical, Ltd. | Drug-delivery endovascular stent and method for treating restenosis |
US20060079439A1 (en) | 2002-03-27 | 2006-04-13 | University Of Utah Research Foundation | Elastin prevents occlusion of body vessels by vascular smooth muscle cells |
US20040126788A1 (en) | 2002-08-13 | 2004-07-01 | Schiemann William P. | Fibulin-5 and uses thereof |
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CA2561495A1 (en) | 2004-03-29 | 2005-10-06 | Kyoto University | Truncated dance, dance complex and method of using these |
WO2005099695A1 (en) | 2004-04-19 | 2005-10-27 | Novartis Ag | Drug delivery systems for the prevention and treatment of vascular diseases |
JP5032973B2 (ja) | 2005-02-07 | 2012-09-26 | 学校法人関西医科大学 | Danceまたはその発現を増強する因子による弾性線維再生の方法 |
CA2637662A1 (en) | 2006-01-31 | 2007-08-09 | Multi-Gene Vascular Systems, Inc. | Drug-eluting intravascular prostheses and methods of use |
-
2000
- 2000-07-20 HU HU0300810A patent/HUP0300810A2/hu unknown
-
2001
- 2001-07-20 AU AU2001278664A patent/AU2001278664A1/en not_active Abandoned
- 2001-07-20 CZ CZ2003253A patent/CZ2003253A3/cs unknown
- 2001-07-20 JP JP2002513384A patent/JP5067822B2/ja not_active Expired - Fee Related
- 2001-07-20 WO PCT/IL2001/000670 patent/WO2002007646A2/en not_active Application Discontinuation
- 2001-07-20 IL IL15394601A patent/IL153946A0/xx unknown
- 2001-07-20 AT AT01956749T patent/ATE469615T1/de not_active IP Right Cessation
- 2001-07-20 PL PL01362561A patent/PL362561A1/xx unknown
- 2001-07-20 EP EP01956749A patent/EP1301146B1/en not_active Expired - Lifetime
- 2001-07-20 DE DE60142290T patent/DE60142290D1/de not_active Expired - Lifetime
- 2001-07-20 CA CA002416548A patent/CA2416548A1/en not_active Abandoned
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2002
- 2002-06-04 US US10/163,387 patent/US7364725B1/en not_active Expired - Fee Related
-
2003
- 2003-01-23 ZA ZA200300635A patent/ZA200300635B/en unknown
-
2006
- 2006-01-31 US US11/344,870 patent/US7563278B2/en not_active Expired - Fee Related
-
2008
- 2008-03-13 US US12/075,657 patent/US8022195B2/en not_active Expired - Fee Related
-
2009
- 2009-06-02 US US12/455,521 patent/US8088160B2/en not_active Expired - Fee Related
Also Published As
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US7563278B2 (en) | 2009-07-21 |
EP1301146B1 (en) | 2010-06-02 |
AU2001278664A1 (en) | 2002-02-05 |
IL153946A0 (en) | 2003-07-31 |
DE60142290D1 (de) | 2010-07-15 |
WO2002007646A2 (en) | 2002-01-31 |
EP1301146A2 (en) | 2003-04-16 |
CA2416548A1 (en) | 2002-01-31 |
WO2002007646A3 (en) | 2002-06-13 |
US8088160B2 (en) | 2012-01-03 |
ZA200300635B (en) | 2004-04-22 |
PL362561A1 (en) | 2004-11-02 |
US8022195B2 (en) | 2011-09-20 |
ATE469615T1 (de) | 2010-06-15 |
CZ2003253A3 (cs) | 2003-05-14 |
JP2004506418A (ja) | 2004-03-04 |
US7364725B1 (en) | 2008-04-29 |
JP5067822B2 (ja) | 2012-11-07 |
US20090263452A1 (en) | 2009-10-22 |
US20080269472A1 (en) | 2008-10-30 |
EP1301146A4 (en) | 2008-11-19 |
US20060275338A1 (en) | 2006-12-07 |
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