DK1086372T3 - Opsamlingsindretning til enkelttrinsanalyse af mundvæsker - Google Patents

Opsamlingsindretning til enkelttrinsanalyse af mundvæsker

Info

Publication number
DK1086372T3
DK1086372T3 DK99914312T DK99914312T DK1086372T3 DK 1086372 T3 DK1086372 T3 DK 1086372T3 DK 99914312 T DK99914312 T DK 99914312T DK 99914312 T DK99914312 T DK 99914312T DK 1086372 T3 DK1086372 T3 DK 1086372T3
Authority
DK
Denmark
Prior art keywords
strip
fluid sample
oral
collection device
oral fluids
Prior art date
Application number
DK99914312T
Other languages
English (en)
Inventor
Ronald William Mink
Andrew Sherman Goldstein
Robert C Bohannon
Original Assignee
Orasure Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orasure Technologies Inc filed Critical Orasure Technologies Inc
Application granted granted Critical
Publication of DK1086372T3 publication Critical patent/DK1086372T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54388Immunochromatographic test strips based on lateral flow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90Plate chromatography, e.g. thin layer or paper chromatography
    • G01N30/91Application of the sample
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Sampling And Sample Adjustment (AREA)
DK99914312T 1998-03-30 1999-03-29 Opsamlingsindretning til enkelttrinsanalyse af mundvæsker DK1086372T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7995898P 1998-03-30 1998-03-30

Publications (1)

Publication Number Publication Date
DK1086372T3 true DK1086372T3 (da) 2006-09-18

Family

ID=22153909

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06011080.6T DK1696236T3 (da) 1998-03-30 1999-03-29 Opsamlingsindretning til analyse af mundvæsker
DK99914312T DK1086372T3 (da) 1998-03-30 1999-03-29 Opsamlingsindretning til enkelttrinsanalyse af mundvæsker

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK06011080.6T DK1696236T3 (da) 1998-03-30 1999-03-29 Opsamlingsindretning til analyse af mundvæsker

Country Status (10)

Country Link
US (2) US20020192839A1 (da)
EP (2) EP1086372B1 (da)
JP (1) JP4623536B2 (da)
AT (1) ATE328278T1 (da)
AU (1) AU3219099A (da)
CA (1) CA2326392A1 (da)
DE (1) DE69931632T2 (da)
DK (2) DK1696236T3 (da)
ES (2) ES2501241T3 (da)
WO (1) WO1999050656A1 (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6365417B1 (en) 2000-02-09 2002-04-02 A-Fem Medical Corporation Collection device for lateral flow chromatography
US6998273B1 (en) 2000-02-09 2006-02-14 A-Fem Medical Corporation Collection device for lateral flow chromatography
EP1380829A4 (en) * 2001-04-20 2009-12-30 Sapporo Immuno Diagnostic Lab INSTRUMENT FOR RECEIVING AND RECOVERING A LIQUID SECRETION OF AN ORAL CAVITY
DE10153925B4 (de) * 2001-11-02 2005-08-11 Unlimited Pharmaceutical Deutschland Gmbh Testgerät zum Nachweis von pharmakologisch wirksamen Verbindungen aus Speichel
US7114403B2 (en) 2003-05-30 2006-10-03 Oakville Hong Kong Co., Ltd Fluid collection and application device and methods of use of same
WO2005008216A2 (en) * 2003-07-11 2005-01-27 Oakville Hong Kong Co., Limited Sanitary fluid collection, application and storage device and methods of use of same
EP1692501B1 (en) 2003-11-14 2016-01-06 Alere Switzerland GmbH Rapid sample analysis and storage devices and methods of use
US7189522B2 (en) 2005-03-11 2007-03-13 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
WO2006098804A2 (en) 2005-03-11 2006-09-21 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
CN101495865B (zh) * 2005-05-20 2015-01-28 北京玛诺生物制药有限公司 口腔流体快速免疫层析检测
US20090312722A1 (en) * 2005-08-04 2009-12-17 Laurent Philippe E Injection fluid leakage collection system and method
NZ567812A (en) 2005-11-30 2011-04-29 Alere Switzerland Gmbh Detecting analytes using a device with a compressible absorbent member and a test element with reagents
JP3157356U (ja) 2006-07-26 2010-02-18 インバーネス・メデイカル・スウイツツアーランド・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 生物学的試料用の分析装置
WO2008105814A2 (en) 2006-08-22 2008-09-04 Los Alamos National Security, Llc Miniturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids
CN102084238B (zh) 2008-05-05 2016-06-01 洛斯阿拉莫斯国家安全有限责任公司 基于高度简化的侧向流动的核酸样品制备和被动流体流动控制
US20110160090A1 (en) * 2008-05-05 2011-06-30 Los Alamos National Laboratory Nanocrystal-Based Lateral Flow Microarrays and Low-Voltage Signal Detection Systems
US20100022916A1 (en) 2008-07-24 2010-01-28 Javanbakhsh Esfandiari Method and Apparatus for Collecting and Preparing Biological Samples for Testing
US8828329B2 (en) 2010-10-01 2014-09-09 Church & Dwight, Co., Inc. Electronic analyte assaying device
US8603835B2 (en) 2011-02-10 2013-12-10 Chembio Diagnostic Systems, Inc. Reduced step dual path immunoassay device and method
KR20140044323A (ko) 2011-04-20 2014-04-14 메사 테크 인터내셔널, 인코포레이티드 핵산의 왕복 증폭 반응
US9510668B2 (en) 2011-04-29 2016-12-06 Colgate-Palmolive Company Oral care implement having visual indicator of depletion of a fluid
ES2607219T3 (es) * 2011-07-15 2017-03-29 Orasure Technologies, Inc. Equipo de Recolección de Muestras
DE202011104802U1 (de) * 2011-08-20 2012-01-26 Christian Kober Strohhalm zur Messung schädlicher Stoffe bzw. von Partydrogen in Getränken
DE202012005997U1 (de) 2012-06-20 2012-07-18 Claus Linder Gefäß für Getränke und Flüssigkeiten jeglicher Art zur Messung schädlicher Stoffe bzw. Rauschgift und Partydrogen in Getränken
JP6180761B2 (ja) 2013-03-13 2017-08-16 デンカ生研株式会社 検査キット
JP6105335B2 (ja) * 2013-03-13 2017-03-29 デンカ生研株式会社 検査キット
SG11201608278WA (en) 2014-04-02 2016-10-28 Chembio Diagnostic Systems Inc Immunoassay utilizing trapping conjugate
US20160116466A1 (en) 2014-10-27 2016-04-28 Chembio Diagnostic Systems, Inc. Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses
CN118788410A (zh) 2015-04-24 2024-10-18 美飒生物技术公司 流体检测盒
EP3612832A4 (en) * 2017-04-17 2020-12-30 Dignity Health SALIVA UREA NITROGEN QUICK DETECTION
EP3574326A1 (en) 2017-05-19 2019-12-04 Philip Morris Products S.a.s. Diagnostic test for distinguishing the smoking status of a subject
WO2019032669A1 (en) * 2017-08-08 2019-02-14 Orasure Technologies, Inc. ASSAY METHODS FOR ENHANCED DETECTION OF ANALYTES
US20200217842A1 (en) * 2017-09-20 2020-07-09 Teijin Limited Substrate for chromatography medium, chromatography medium, and immunochromatographic strip
US20190170773A1 (en) * 2017-12-06 2019-06-06 Dawn Maslar Testosterone Saliva Test
US20210025905A1 (en) * 2017-12-06 2021-01-28 Dawn Maslar Testosterone Saliva Test
FR3110574A1 (fr) 2020-05-20 2021-11-26 Vetophage Capture de bacteries a l’aide de bacteriophages ou de proteines de bacteriophage
FR3110703A1 (fr) 2020-05-20 2021-11-26 Vetophage Dispositif de detection d’une bacterie d’interet
US11318467B2 (en) * 2020-05-29 2022-05-03 Tokitae Llc Assay structures for multi-step biochemical assays
EP4330669A1 (en) * 2021-04-26 2024-03-06 OraSure Technologies, Inc. Direct sample collection pad and method of use for assay diagnosis
USD982174S1 (en) * 2021-04-26 2023-03-28 Orasure Technologies, Inc. Direct sample collection pad
EP4341387A1 (fr) 2021-05-20 2024-03-27 Vetophage Proteines de liaison au recepteur d'un bacteriophage et leurs utilisations
KR200496802Y1 (ko) * 2021-06-07 2023-05-02 황유안 타액으로 흡연 여부를 검출하는 흡연 테스트기
WO2024020586A2 (en) * 2022-07-21 2024-01-25 Cavisense Inc. Oral sampling device
NL2033568B1 (en) * 2022-11-18 2024-05-30 Daklapack Europe B V Flow assay device for collecting a blood sample

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) * 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4014322A (en) * 1975-10-23 1977-03-29 The Kendall Company Specimen collecting device and method
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
NL7807532A (nl) 1978-07-13 1980-01-15 Akzo Nv Metaal-immunotest.
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
US4446232A (en) 1981-10-13 1984-05-01 Liotta Lance A Enzyme immunoassay with two-zoned device having bound antigens
US4624929A (en) * 1984-12-03 1986-11-25 Syntex (U.S.A.) Inc. Sample collector and assay device and method for its use
US4635488A (en) * 1984-12-03 1987-01-13 Schleicher & Schuell, Inc. Nonintrusive body fluid samplers and methods of using same
US4806311A (en) 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having labeled reagent concentration zone
US4868108A (en) 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
CA1303983C (en) 1987-03-27 1992-06-23 Robert W. Rosenstein Solid phase assay
US4857453A (en) * 1987-04-07 1989-08-15 Syntex (U.S.A.) Inc. Immunoassay device
DE291194T1 (de) * 1987-04-27 1992-03-19 Unilever N.V., Rotterdam Immunoassays und vorrichtungen dafuer.
US4855240A (en) 1987-05-13 1989-08-08 Becton Dickinson And Company Solid phase assay employing capillary flow
DE3717401A1 (de) * 1987-05-23 1988-12-08 Behringwerke Ag Einschritt-immuntest zur bestimmung von antigen-spezifischen antikoerpern aus einer der immunglobulin-klassen a, m, d oder e und dazu geeignetes mittel
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
US4956302A (en) * 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
CA1312544C (en) 1987-12-21 1993-01-12 James L. Wilcox Chromatographic binding assay devices and methods
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
DE3842702A1 (de) * 1988-12-19 1990-06-21 Boehringer Mannheim Gmbh Testtraeger zur analytischen untersuchung einer probenfluessigkeit mit hilfe einer spezifischen bindungsreaktion zweier bioaffiner bindungspartner und entsprechendes testverfahren
US5103836A (en) * 1990-02-28 1992-04-14 Epitope, Inc. Oral collection device and kit for immunoassay
US5479937A (en) 1989-09-21 1996-01-02 Epitope, Inc. Oral collection device
US5376337A (en) * 1990-12-18 1994-12-27 Seymour; Eugene H. Saliva sampling device and sample adequacy system
US5393496A (en) * 1990-12-18 1995-02-28 Saliva Diagnostic Systems, Inc. Saliva sampling device and sample adequacy system
US5380492A (en) * 1990-12-18 1995-01-10 Seymour; Eugene H. Sampling device and sample adequacy system
US5283038A (en) * 1990-12-18 1994-02-01 Saliva Diagnostic Systems, Inc. Fluid sampling and testing device
US5268148A (en) * 1990-12-18 1993-12-07 Saliva Diagnostic Systems, Inc. Saliva sampling device and sample adequacy system
JPH04355339A (ja) * 1991-06-01 1992-12-09 Meito Sangyo Kk 微量検体採取用具
US5726010A (en) * 1991-07-31 1998-03-10 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US5211182A (en) * 1991-10-23 1993-05-18 Deutsch Marshall E Home ovulation test kit and method
US5334502A (en) * 1991-11-27 1994-08-02 Osborn Laboratories, Inc. Method of collecting, identifying, and quantifying saliva
US5820826A (en) * 1992-09-03 1998-10-13 Boehringer Mannheim Company Casing means for analytical test apparatus
ATE154979T1 (de) * 1993-03-17 1997-07-15 Akzo Nobel Nv Vorrichtung zur bestimmung einer spezifisch reagierenden substanz
US5494646A (en) * 1993-04-14 1996-02-27 Seymour; Eugene H. Sampling device and sample adequacy system
DE4323672A1 (de) * 1993-07-15 1995-01-19 Boehringer Mannheim Gmbh Vorrichtung zur gleichzeitigen Bestimmung von Analyten
US5714341A (en) * 1994-03-30 1998-02-03 Epitope, Inc. Saliva assay method and device
US5569608A (en) 1995-01-30 1996-10-29 Bayer Corporation Quantitative detection of analytes on immunochromatographic strips
US5609160A (en) * 1995-03-30 1997-03-11 Ortho Pharmaceutical Corporation In home oral fluid sample collection device and package for mailing of such device
WO1996036878A1 (en) * 1995-05-19 1996-11-21 Universal Healthwatch, Inc. Rapid self-contained assay format
US5656502A (en) * 1995-06-07 1997-08-12 Diagnostic Chemicals Limited Test strip holder and method of use
US5695929A (en) 1995-06-07 1997-12-09 Goldstein; Andrew S. Substitute saliva standard
WO1997003209A1 (en) * 1995-07-12 1997-01-30 Charm Sciences, Inc. Test apparatus, system and method for the detection of test samples
US5741662A (en) * 1995-12-18 1998-04-21 Quidel Corporation Direct stain specific binding assays for microorganisms
US6001658A (en) * 1996-09-13 1999-12-14 Diagnostic Chemicals Limited Test strip apparatus and method for determining presence of analyte in a fluid sample
EP1150122A3 (en) * 1996-12-05 2003-02-12 Idego ApS Sensor laminates and multi-sectioned fluid delivery devices for detecting by immunoassay target molecules in biological fluids
GB2322192B (en) * 1997-02-14 2001-01-31 Unilever Plc Assay devices
US6046057A (en) * 1997-10-24 2000-04-04 Carter-Wallace, Inc. Analyte assaying device
US6146590A (en) * 1998-06-29 2000-11-14 Mainline Technology, Inc. Vessel for an analytic test device
US6248598B1 (en) * 1998-09-17 2001-06-19 Stuart C. Bogema Immunoassay that provides for both collection of saliva and assay of saliva for one or more analytes with visual readout
US6140136A (en) * 1998-09-18 2000-10-31 Syntron Bioresearch, Inc. Analytical test device and method of use
US6316205B1 (en) * 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection

Also Published As

Publication number Publication date
US20020192839A1 (en) 2002-12-19
DK1696236T3 (da) 2014-08-18
EP1086372B1 (en) 2006-05-31
ES2501241T3 (es) 2014-10-01
EP1086372A4 (en) 2002-09-18
EP1696236B1 (en) 2014-07-16
DE69931632D1 (de) 2006-07-06
DE69931632T2 (de) 2006-12-07
US20100239458A1 (en) 2010-09-23
ATE328278T1 (de) 2006-06-15
EP1696236A3 (en) 2006-09-20
JP4623536B2 (ja) 2011-02-02
WO1999050656A1 (en) 1999-10-07
CA2326392A1 (en) 1999-10-07
ES2264580T3 (es) 2007-01-01
JP2002510048A (ja) 2002-04-02
EP1696236A2 (en) 2006-08-30
EP1696236A8 (en) 2010-06-02
EP1086372A1 (en) 2001-03-28
AU3219099A (en) 1999-10-18

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