ATE466079T1 - Nukleinsäure konstrukten, pharmazeutische kompositionen und methoden für die behandlung von krebs - Google Patents

Nukleinsäure konstrukten, pharmazeutische kompositionen und methoden für die behandlung von krebs

Info

Publication number
ATE466079T1
ATE466079T1 AT06780498T AT06780498T ATE466079T1 AT E466079 T1 ATE466079 T1 AT E466079T1 AT 06780498 T AT06780498 T AT 06780498T AT 06780498 T AT06780498 T AT 06780498T AT E466079 T1 ATE466079 T1 AT E466079T1
Authority
AT
Austria
Prior art keywords
nucleic acid
methods
cancer
treatment
pharmaceutical compositions
Prior art date
Application number
AT06780498T
Other languages
English (en)
Inventor
Avraham Hochberg
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Application granted granted Critical
Publication of ATE466079T1 publication Critical patent/ATE466079T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT06780498T 2005-09-22 2006-09-21 Nukleinsäure konstrukten, pharmazeutische kompositionen und methoden für die behandlung von krebs ATE466079T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71917805P 2005-09-22 2005-09-22
PCT/IL2006/001110 WO2007034487A1 (en) 2005-09-22 2006-09-21 Nucleic acid constructs, pharmaceutical compositions and methods of using same for treating cancer

Publications (1)

Publication Number Publication Date
ATE466079T1 true ATE466079T1 (de) 2010-05-15

Family

ID=37575053

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06780498T ATE466079T1 (de) 2005-09-22 2006-09-21 Nukleinsäure konstrukten, pharmazeutische kompositionen und methoden für die behandlung von krebs

Country Status (6)

Country Link
US (1) US8034914B2 (de)
EP (1) EP1926814B1 (de)
JP (1) JP2009508516A (de)
AT (1) ATE466079T1 (de)
DE (1) DE602006014009D1 (de)
WO (1) WO2007034487A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1915448B1 (de) 2005-07-07 2013-09-04 Yissum Research Development Company, of The Hebrew University of Jerusalem Nukleinsäuremittel zur herunterregulierung von h19 sowie verfahren zur verwendung davon
KR101539796B1 (ko) * 2007-10-25 2015-07-27 이섬 리서치 디벨러프먼트 컴파니 오브 더 히브루 유니버시티 오브 예루살렘 엘티디. 암 치료법을 위한 다중 발현 카세트를 포함하는 구조물
US8492133B2 (en) 2009-01-20 2013-07-23 Ramot At Tel Aviv University, Ltd. MIR-21 promoter driven targeted cancer therapy
CA2870006A1 (en) * 2012-04-10 2013-10-17 Agency For Science, Technology And Research Methods for bladder cancer therapy using baculoviral vectors
WO2014197586A1 (en) 2013-06-04 2014-12-11 Virginia Commonwealth University Mda-9/syntenin promoter to image and treat metastatic cancer cells
WO2014197598A2 (en) 2013-06-04 2014-12-11 The Johns Hopkins University Tripartite cancer theranostic nucleic acid constructs
EP3004357A4 (de) 2013-06-04 2017-01-11 The Johns Hopkins University Peg-prom-vermittelte oberflächenexpression von avidin/streptavidin
EP3004153B1 (de) 2013-06-04 2019-10-30 Virginia Commonwealth University Rekombinantes cytokin für eine krebstherapie
EP3003022B1 (de) 2013-06-04 2017-11-22 Virginia Commonwealth University Verwendung eines trunkierten ccn1-promotors für krebsdiagnostik, therapeutika und theranostika
US9790488B2 (en) 2013-08-02 2017-10-17 Agency For Science, Technology And Research Mutated internal ribosomal entry site (IRES) for controlled gene expression
BR112017023788A2 (pt) 2015-05-05 2018-10-16 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd composições de ácido nucleico?polímero catiônico e processo para a preparação de dita composição

Family Cites Families (27)

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Publication number Priority date Publication date Assignee Title
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
NL171930C (nl) 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3850578A (en) 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
US3935074A (en) 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4879219A (en) 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US5011771A (en) 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5281521A (en) 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
US5830686A (en) 1994-01-13 1998-11-03 Calydon Tissue-specific enhancer active in prostate
IL108879A (en) 1994-03-07 2000-08-31 Yissum Res Dev Co Diagnostic assay for malignancies using the H19 gene and kit
US6087164A (en) 1997-10-03 2000-07-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods and compositions for inducing tumor-specific cytotoxicity
US20040009146A1 (en) * 2002-02-26 2004-01-15 Osvaldo Podhajcer Anti-tumor vaccine and method
CA2498783A1 (en) 2002-09-12 2004-03-25 Yissum Research Development Company Of The Hebrew University Of Jerusale M Method for detection of micro-metastasis

Also Published As

Publication number Publication date
DE602006014009D1 (de) 2010-06-10
WO2007034487A8 (en) 2007-07-05
EP1926814A1 (de) 2008-06-04
US20090221681A1 (en) 2009-09-03
EP1926814B1 (de) 2010-04-28
JP2009508516A (ja) 2009-03-05
US8034914B2 (en) 2011-10-11
WO2007034487B1 (en) 2007-08-23
WO2007034487A1 (en) 2007-03-29

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