IL47835A - Immunoassay method by fluorescence quenching - Google Patents

Immunoassay method by fluorescence quenching

Info

Publication number
IL47835A
IL47835A IL47835A IL4783575A IL47835A IL 47835 A IL47835 A IL 47835A IL 47835 A IL47835 A IL 47835A IL 4783575 A IL4783575 A IL 4783575A IL 47835 A IL47835 A IL 47835A
Authority
IL
Israel
Prior art keywords
pair
ligand
amount
bound
antibodies
Prior art date
Application number
IL47835A
Other languages
English (en)
Other versions
IL47835A0 (en
Original Assignee
Syva Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syva Co filed Critical Syva Co
Publication of IL47835A0 publication Critical patent/IL47835A0/xx
Publication of IL47835A publication Critical patent/IL47835A/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/18—Water
    • G01N33/1826—Organic contamination in water
    • G01N33/1833—Oil in water
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/816—Alkaloids, amphetamines, and barbiturates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
IL47835A 1974-08-12 1975-07-29 Immunoassay method by fluorescence quenching IL47835A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49716774A 1974-08-12 1974-08-12
US05/591,386 US3996345A (en) 1974-08-12 1975-06-30 Fluorescence quenching with immunological pairs in immunoassays

Publications (2)

Publication Number Publication Date
IL47835A0 IL47835A0 (en) 1975-10-15
IL47835A true IL47835A (en) 1978-08-31

Family

ID=27052409

Family Applications (1)

Application Number Title Priority Date Filing Date
IL47835A IL47835A (en) 1974-08-12 1975-07-29 Immunoassay method by fluorescence quenching

Country Status (13)

Country Link
US (1) US3996345A (fr)
JP (1) JPS6018940B2 (fr)
AU (1) AU501140B2 (fr)
BR (1) BR7505107A (fr)
CA (1) CA1042792A (fr)
CH (1) CH621873A5 (fr)
DE (1) DE2535574C2 (fr)
ES (1) ES440173A1 (fr)
FR (1) FR2282115A1 (fr)
GB (2) GB1526241A (fr)
IL (1) IL47835A (fr)
NL (1) NL185423C (fr)
SE (2) SE427504B (fr)

Families Citing this family (1844)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630328B2 (en) 1909-07-15 2003-10-07 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms
US4199559A (en) * 1974-08-12 1980-04-22 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4174384A (en) * 1975-06-30 1979-11-13 Syva Company Fluorescence quenching with immunological pairs in immunoassays
GB1573212A (en) * 1976-04-15 1980-08-20 Technicon Instr Immunoassay for gentamicin
US4160818A (en) * 1976-04-15 1979-07-10 Technicon Instruments Corporation Fluorimetric immunoassay for diphenylhydantoin
JPS5836308B2 (ja) * 1977-02-10 1983-08-08 大塚製薬株式会社 抗体の製造方法
IT1079045B (it) * 1977-05-16 1985-05-08 Syva Co Analisi imuunologica fluorescente a doppio ricettore
FR2394085A1 (fr) * 1977-06-10 1979-01-05 Syva Co Methode qualitative et quantitative de dosage fluorimetrique de composes organiques doues d'activite physiologique
US4160645A (en) * 1977-07-14 1979-07-10 Syva Company Catalyst mediated competitive protein binding assay
US4208479A (en) * 1977-07-14 1980-06-17 Syva Company Label modified immunoassays
USRE34394E (en) * 1978-01-23 1993-09-28 Baxter Diagnostics Inc. Method and composition for double receptor, specific binding assays
US4215102A (en) * 1979-01-05 1980-07-29 Lee Sin H Cytochemical agents and methods for the detection of steroid hormone receptors in human tissues
US4331590A (en) * 1978-03-13 1982-05-25 Miles Laboratories, Inc. β-Galactosyl-umbelliferone-labeled protein and polypeptide conjugates
US4220450A (en) * 1978-04-05 1980-09-02 Syva Company Chemically induced fluorescence immunoassay
US4235869A (en) * 1978-05-16 1980-11-25 Syva Company Assay employing a labeled Fab-fragment ligand complex
US4193983A (en) * 1978-05-16 1980-03-18 Syva Company Labeled liposome particle compositions and immunoassays therewith
US4318707A (en) * 1978-11-24 1982-03-09 Syva Company Macromolecular fluorescent quencher particle in specific receptor assays
US4238195A (en) * 1979-01-18 1980-12-09 Miles Laboratories, Inc. Fluorescer-labeled specific binding assays
CA1121345A (fr) * 1979-03-05 1982-04-06 Robert A. Yoshida Methode pour les epreuves de dosage par radiocompetition a l'aide de proteines liantes inhibant les interferences non specifiques
US4256834A (en) * 1979-04-09 1981-03-17 Syva Company Fluorescent scavenger particle immunoassay
US4284412A (en) * 1979-07-13 1981-08-18 Ortho Diagnostics, Inc. Method and apparatus for automated identification and enumeration of specified blood cell subclasses
US4287300A (en) * 1979-07-26 1981-09-01 Syva Company Charge effects in enzyme immunoassays
US4351760A (en) * 1979-09-07 1982-09-28 Syva Company Novel alkyl substituted fluorescent compounds and polyamino acid conjugates
NL8000173A (nl) * 1980-01-11 1981-08-03 Akzo Nv Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen.
US4329461A (en) * 1980-01-11 1982-05-11 Syva Company Fluorescent thyroid hormone conjugates and their uses
US4401764A (en) * 1980-02-07 1983-08-30 Technicon Instruments Corporation Immunoassays employing labeled reagent and a conjugate having two binding sites
US4318981A (en) * 1980-04-24 1982-03-09 Miles Laboratories, Inc. Homogeneous specific binding assay employing an intramolecularly modulated photogenic enzyme substrate label
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
EP0050684B1 (fr) * 1980-10-27 1986-01-22 Syva Company Dérivés de fluorescéine substitués par des groupements éthers utilisés comme agents fluorescents et extincteurs
JPS5782387A (en) * 1980-10-29 1982-05-22 Syva Co Novel ether substituted fluorescein compound
US4385126A (en) * 1980-11-19 1983-05-24 International Diagnostic Technology, Inc. Double tagged immunoassay
US4378458A (en) * 1981-03-30 1983-03-29 Baker Instruments Corporation Novel chromogenic and/or fluorogenic substrates for monitoring catalytic or enzymatic activity
US4378428A (en) * 1981-03-30 1983-03-29 Baker Instruments Corporation Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays
US4785080A (en) * 1981-03-30 1988-11-15 Baker Instruments Corporation Labeled analytes
US4442218A (en) * 1981-05-27 1984-04-10 Corning Glass Works Method of measuring degree of partitioning
JPS585659A (ja) * 1981-06-24 1983-01-13 ハイブリテツク　インコ−ポレ−テツド 単クロ−ン性抗体を使用する免疫学的、抑制試験
US4434150A (en) 1981-10-19 1984-02-28 Ortho Diagnostic Systems, Inc. Immunological reagents employing polymeric backbone possessing reactive functional groups
AU9094982A (en) * 1982-02-01 1983-08-11 Miles Laboratories Inc. Photogenic labels to alleviate quenching in immuno assays
US4472301A (en) * 1982-05-27 1984-09-18 Miles Laboratories, Inc. Propranolol immunogen and antibodies
US4687732A (en) * 1983-06-10 1987-08-18 Yale University Visualization polymers and their application to diagnostic medicine
US4719176A (en) * 1983-10-31 1988-01-12 Klotz Irving M Enzyme-free diagnostic binding reagents
US4865997A (en) * 1984-02-23 1989-09-12 Becton Dickinson And Company Assay for ligands by separating bound and free tracer from sample
US4708929A (en) * 1984-10-29 1987-11-24 Microgenics Corporation Methods for protein binding enzyme complementation assays
US4645828A (en) 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
US4791068A (en) * 1984-06-22 1988-12-13 Scripps Clinic And Research Foundation Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators
US4666862A (en) * 1984-08-14 1987-05-19 Ortho Diagnostic Systems Inc. Fluorescent energy transfer with phycobiliproteins
US5310687A (en) * 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
US5221605A (en) * 1984-10-31 1993-06-22 Igen, Inc. Luminescent metal chelate labels and means for detection
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US4743561A (en) * 1985-03-05 1988-05-10 Abbott Laboratories Luminescent assay with a reagent to alter transmitive properties of assay solution
IE64785B1 (en) 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
JPH0672883B2 (ja) * 1985-06-19 1994-09-14 コニカ株式会社 分析素子
US5279943A (en) * 1985-08-02 1994-01-18 Compagnie Oris Industrie Homogeneous process for the detection and/or determination by luminescence of an analyte in a medium in which it may be present
FR2585836B1 (fr) * 1985-08-02 1987-11-27 Commissariat Energie Atomique Procede homogene de detection et/ou de determination par luminescence d'un analyte dans un milieu susceptible de le contenir
US4689397A (en) * 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4777128A (en) * 1986-05-27 1988-10-11 Ethigen Corporation Fluorescence immunoassay involving energy transfer between two fluorophores
FR2617974B1 (fr) * 1987-07-07 1992-11-13 Stabiligen Procede de dosage immunologique par bio- ou chimio- luminescence
US5384241A (en) * 1987-09-11 1995-01-24 Enzo Diagnostics, Inc. Specific binding assay compound with inhibitive self-quenching characteristics
US5039607A (en) * 1988-05-17 1991-08-13 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5334513A (en) * 1988-05-17 1994-08-02 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5053054A (en) * 1988-09-12 1991-10-01 Ortho Pharmaceutical Corporation Methods and reagents for staining intracellular components
US5135863A (en) * 1988-12-23 1992-08-04 Syntex (U.S.A.) Inc. Compositions and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine
US5132432A (en) * 1989-09-22 1992-07-21 Molecular Probes, Inc. Chemically reactive pyrenyloxy sulfonic acid dyes
JP3184894B2 (ja) * 1989-10-05 2001-07-09 エックスオックスエミス， インコーポレイテッド ハロペルオキシターゼ酸至適化学的発光分析系
US5108899A (en) * 1989-10-31 1992-04-28 Exoxemis, Inc. Chemiluminescence assay of in vivo inflammation
US5532138A (en) * 1990-04-26 1996-07-02 Behringwerke Ag Method and kits for determining peroxidatively active catalysts
US5614504A (en) * 1990-08-01 1997-03-25 The University Of South Florida Method of making inosine monophosphate derivatives and immunopotentiating uses thereof
US5340716A (en) * 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
US5578498A (en) 1991-05-22 1996-11-26 Behringwerke Ag Metal chelate containing compositions for use in chemiluminescent assays
US6251581B1 (en) * 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5279937A (en) * 1992-04-30 1994-01-18 Detechnology Canada Use of macroglobulins to improve the signal-to-background ratio in affinity binding assays
DK0653066T3 (da) * 1992-07-31 1998-09-23 Dade Behring Marburg Gmbh Fotoaktiverbare kemiluminescerende matricer
US5874423A (en) * 1992-09-10 1999-02-23 Yissum Research Development Co. Of The Hebrew University Of Jerusalem Digitalis-like compounds
US6033898A (en) * 1992-12-30 2000-03-07 Abbott Laboratories Enhanced yeast expression using regulatory control sequences from yeast sorbitol dehydrogenase gene
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
US6953573B1 (en) 1993-03-17 2005-10-11 University Of Washington Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated
AU679008B2 (en) * 1993-05-06 1997-06-19 Chiron Diagnostics Corporation Mixed luminescent conjugate test assays
US6562333B1 (en) 1993-06-14 2003-05-13 Schering Corporation Purified mammalian CTLA-8 antigens and related reagents
US5516639A (en) * 1993-07-22 1996-05-14 Mayo Foundation For Medical Education And Research Antibodies specific for human prostate glandular kallkrein
US6103237A (en) * 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
US20040259113A1 (en) * 1993-07-22 2004-12-23 Mayo Foundation For Medical Education And Research, Hybritech Incorporated Method for detection of metastatic prostate cancer
US5684144A (en) * 1993-07-28 1997-11-04 University Of North Texas Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof
US6238931B1 (en) * 1993-09-24 2001-05-29 Biosite Diagnostics, Inc. Fluorescence energy transfer in particles
US7083984B2 (en) 1993-09-24 2006-08-01 Biosite, Inc. Hybrid phthalocyanine derivatives and their uses
US7322927B2 (en) 1993-09-24 2008-01-29 Biosite, Inc. Hybrid phthalocyanine derivatives and their uses
US5824799A (en) * 1993-09-24 1998-10-20 Biosite Diagnostics Incorporated Hybrid phthalocyanine derivatives and their uses
US6251687B1 (en) 1993-09-24 2001-06-26 Biosite Diagnostics, Inc. Fluorescence energy transfer and intramolecular energy transfer in particles using novel compounds
US6406855B1 (en) 1994-02-17 2002-06-18 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
EP0804593A1 (fr) * 1994-05-10 1997-11-05 Mayo Foundation For Medical Education And Research Polypeptide hk2 recombine
WO1995034640A1 (fr) * 1994-06-13 1995-12-21 Henry Ford Health System Neuronatine, nouveau gene neuronal neonatal
AU691958B2 (en) 1994-08-12 1998-05-28 Myriad Genetics, Inc. 17q-linked breast and ovarian cancer susceptibility gene
WO1996005306A2 (fr) 1994-08-12 1996-02-22 Myriad Genetics, Inc. Mutations et polymorphismes in vivo du gene de la susceptibilite au cancer du sein et des ovaires lie au 17q
US8236493B2 (en) 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6974666B1 (en) * 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US5843673A (en) * 1994-10-25 1998-12-01 Curators Of The University Of Missouri Method of screening for endometriosis
US6531277B2 (en) 1994-10-25 2003-03-11 The Curators Of The University Of Missouri Endometriosis-specific secretory protein
US20030152909A1 (en) * 1994-11-16 2003-08-14 Mitrani Eduardo N. In vitro micro-organs, and uses related thereto
US5633149A (en) * 1994-12-07 1997-05-27 Incyte Pharmaceuticals, Inc. Polynucleotide encoding novel chemokine expressed in inflamed adenoid
US6692920B1 (en) * 1994-12-07 2004-02-17 Incyte Corporation Antibodies to a chemokine expressed in inflamed adenoid
DK0800578T3 (da) * 1994-12-28 2003-08-11 Univ Kentucky Rekombinant monoklonalt anti-idiotype antistof 3H1
US6949244B1 (en) * 1995-12-20 2005-09-27 The Board Of Trustees Of The University Of Kentucky Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof
US5952238A (en) 1995-02-02 1999-09-14 Chugai Seiyaku Kabushiki Kaisha Method of assaying specimen substance by controlling dose of chemiluminescence
US7005509B1 (en) 1995-02-17 2006-02-28 Incyte Corporation Chemokine PANEC-1 polynucleotides and compositions and methods related thereto
US5858661A (en) 1995-05-16 1999-01-12 Ramot-University Authority For Applied Research And Industrial Development Ataxia-telangiectasia gene and its genomic organization
US5728807A (en) * 1995-05-16 1998-03-17 Ramot-University Authority For Applied Research And Industrial Development, Ltd. Mutated proteins associated with ataxia-telangiectasia
US5777093A (en) * 1995-05-16 1998-07-07 Ramot-University Authority For Applied Research & Industrial Development Ltd. cDNAs associated with ataxia-telangiectasia
GB0112226D0 (en) * 2001-05-18 2001-07-11 Danisco Method of improving dough and bread quality
EP2258726A1 (fr) 1995-06-14 2010-12-08 The Regents of the University of California Anticorps humains à haute affinité pour c-erbB-2
US5837492A (en) 1995-12-18 1998-11-17 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
CA2239733C (fr) 1995-12-18 2001-04-03 Myriad Genetics, Inc. Gene de predisposition au cancer du sein lie au chromosome 13
US5741662A (en) * 1995-12-18 1998-04-21 Quidel Corporation Direct stain specific binding assays for microorganisms
US6965020B2 (en) 1996-01-23 2005-11-15 Affymetrix, Inc. Nucleic acid labeling compounds
US20010018514A1 (en) * 1998-07-31 2001-08-30 Mcgall Glenn H. Nucleic acid labeling compounds
US6864059B2 (en) * 1996-01-23 2005-03-08 Affymetrix, Inc. Biotin containing C-glycoside nucleic acid labeling compounds
US7423143B2 (en) * 1996-01-23 2008-09-09 Affymetrix. Inc. Nucleic acid labeling compounds
US20040210045A1 (en) * 1996-01-23 2004-10-21 Mcgall Glenn Nucleic acid labeling compounds
US7291463B2 (en) * 1996-01-23 2007-11-06 Affymetrix, Inc. Nucleic acid labeling compounds
EP0880598A4 (fr) * 1996-01-23 2005-02-23 Affymetrix Inc Evaluation rapide de difference d'abondance d'acides nucleiques, avec un systeme d'oligonucleotides haute densite
US7282327B2 (en) * 1996-01-23 2007-10-16 Affymetrix, Inc. Nucleic acid labeling compounds
US6228575B1 (en) 1996-02-08 2001-05-08 Affymetrix, Inc. Chip-based species identification and phenotypic characterization of microorganisms
EP1728875A3 (fr) 1996-02-08 2007-05-09 Affymetrix, Inc. Spéciation de micro-organismes à partir de micro plaquettes et caractérisation des phénotypes de ceux-ci
US6924094B1 (en) * 1996-02-08 2005-08-02 Affymetrix, Inc. Chip-based species identification and phenotypic characterization of microorganisms
EP0904542B1 (fr) * 1996-03-01 2005-06-29 Beckman Coulter, Inc. Systeme d'essais multiples simultanes de fixation de ligands
US5882644A (en) * 1996-03-22 1999-03-16 Protein Design Labs, Inc. Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof
US6129917A (en) * 1996-03-22 2000-10-10 The University Of Georgia Research Foundation, Inc. Immunogenic compositions comprising porphyromonas gingivalis proteins and/or peptides and methods
US6942862B2 (en) * 1996-04-01 2005-09-13 University Of Washington Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins
US6162931A (en) 1996-04-12 2000-12-19 Molecular Probes, Inc. Fluorinated xanthene derivatives
ES2312177T3 (es) * 1996-05-22 2009-02-16 Viventia Biotech Inc. Fragmentos de union a antigenos que detectan especificamente celulas cancerosas, nucleotidos que codifican los fragmentos y el uso de los mismos para la profilaxis y deteccion de canceres.
US6063908A (en) * 1996-07-02 2000-05-16 Roche Diagnostics Corporation Reagents for lysergic acid diethylamide immunoassay
CA2260361A1 (fr) 1996-07-08 1998-01-15 Burstein Laboratories, Inc Procede et dispositif a element de signal clivable
US6342349B1 (en) 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
US6331275B1 (en) 1996-07-08 2001-12-18 Burstein Technologies, Inc. Spatially addressable, cleavable reflective signal elements, assay device and method
US20050069923A1 (en) * 1996-07-08 2005-03-31 Mullis Kary Banks Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
US5866336A (en) * 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6171801B1 (en) 1996-07-18 2001-01-09 Dade Behring Marburg Gmbh Methods for releasing a ligand from a complex
WO1998003876A1 (fr) * 1996-07-18 1998-01-29 Behringwerke Aktiengesellschaft Reactif pour le dosage de l'acide mycophenolique
US5853990A (en) * 1996-07-26 1998-12-29 Edward E. Winger Real time homogeneous nucleotide assay
JP4440344B2 (ja) 1996-08-16 2010-03-24 シェーリング コーポレイション 哺乳動物細胞表面抗原；関連試薬
AU737323B2 (en) 1996-09-24 2001-08-16 Genentech, Inc. A family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
US20070299005A1 (en) * 1996-09-24 2007-12-27 Tanox, Inc. Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
US6808880B2 (en) * 1996-10-01 2004-10-26 Geron Corporation Method for detecting polynucleotides encoding telomerase
US6475789B1 (en) * 1996-10-01 2002-11-05 University Technology Corporation Human telomerase catalytic subunit: diagnostic and therapeutic methods
IL129103A0 (en) * 1996-10-01 2000-02-17 Geron Corp Human telomerase catalytic subunit and pharmaceutical compositions containing same
US6093809A (en) * 1996-10-01 2000-07-25 University Technology Corporation Telomerase
US6261836B1 (en) 1996-10-01 2001-07-17 Geron Corporation Telomerase
US7585622B1 (en) * 1996-10-01 2009-09-08 Geron Corporation Increasing the proliferative capacity of cells using telomerase reverse transcriptase
US6610839B1 (en) * 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
GB9907461D0 (en) 1999-03-31 1999-05-26 King S College London Neurite regeneration
US6479263B1 (en) 1996-11-14 2002-11-12 Baylor College Of Medicine Method for detection of micrometastatic prostate cancer
WO1998025958A2 (fr) 1996-12-13 1998-06-18 Schering Corporation Antigenes de surface de cellules de mammiferes
US5840322A (en) * 1996-12-19 1998-11-24 Ramot-University Authority For Applied Research & Industrial Devel. Ltd. Anti-oral-microbial adhesion fraction derived from vaccinium
ES2331595T3 (es) 1997-02-07 2010-01-08 The Government Of The Usa As Represented By The Secretary Of Department Of Health And Human Services Factor neurotrofico dependiente de actividad iii (adnf iii).
ATE273381T1 (de) 1997-02-12 2004-08-15 Eugene Y Chan Verfahren zur analyse von polymeren
US20050013825A1 (en) * 1997-04-18 2005-01-20 Geron Corporation Vaccine containing the catalytic subunit of telomerase for treating cancer
US7413864B2 (en) * 1997-04-18 2008-08-19 Geron Corporation Treating cancer using a telomerase vaccine
US7622549B2 (en) * 1997-04-18 2009-11-24 Geron Corporation Human telomerase reverse transcriptase polypeptides
US6103536A (en) 1997-05-02 2000-08-15 Silver Lake Research Corporation Internally referenced competitive assays
CN1935840A (zh) 1997-05-07 2007-03-28 先灵公司 人Toll样受体蛋白、相关试剂和方法
US7115722B1 (en) 1997-05-22 2006-10-03 Viventia Biotech, Inc. Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
US7314711B2 (en) * 1997-05-23 2008-01-01 Bioveris Corporation Assays employing electrochemiluminescent labels and electrochemiluminescence quenchers
US20020098190A1 (en) * 1997-06-13 2002-07-25 Malaya Chatterjee Compositions and methods for treating tumors bearing HMFG and CEA antigens
US6235486B1 (en) 1997-06-20 2001-05-22 Mayo Foundation For Medical Education & Research Method for detection of breast cancer
US20020122807A1 (en) * 1998-07-07 2002-09-05 Dan Michael D. Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
DE69839555D1 (de) 1997-07-09 2008-07-10 Schering Corp Isolierte dentritische zell membran protein gene
EP0927266A1 (fr) 1997-07-11 1999-07-07 The University Of North Texas Health Science Center At Fort Worth GENE $i(csrB) DE L'$i(ESCHERICHIA COLI), ARN CODE PAR CE GENE ET PROCEDES D'UTILISATION
US6762039B2 (en) * 1997-07-15 2004-07-13 Genencor International, Inc. Bacillus subtillis with an inactivated cysteine protease-1
US6723550B1 (en) * 1997-07-15 2004-04-20 Genencor International, Inc. Proteases from gram-positive organisms
US20030157642A1 (en) * 1997-07-15 2003-08-21 Caldwell Robert M. Increasing production of proteins in gram-positive microorganisms
US6506579B1 (en) 1997-07-15 2003-01-14 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms using SecG
US6521421B1 (en) * 1997-07-16 2003-02-18 Genencor International, Inc. Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same
CO4810232A1 (es) 1997-07-25 1999-06-30 Schering Corp Citoquinas de mamiferos y sus secuencias codificadoras
US6180411B1 (en) 1997-08-01 2001-01-30 The Regents Of The University Of California Light-triggered indicators that memorize analyte concentrations
EP1003861B1 (fr) 1997-08-01 2006-10-04 Schering Corporation Proteines de membrane cellulaire mammalienne et reactifs associes
US5929049A (en) * 1997-08-08 1999-07-27 Dade Behring Marburg Gmbh Polysaccharide conjugates of biomolecules
AU9110798A (en) * 1997-08-21 1999-03-08 Quark Biotech, Inc. Hypoxia-regulated genes
US20030104973A1 (en) * 1997-08-21 2003-06-05 Quark Biotech, Inc. Hypoxia-regulated genes
US7973156B2 (en) * 1997-08-21 2011-07-05 Quark Pharmaceuticals Inc. Hypoxia-regulated genes
US7252950B1 (en) * 1997-09-04 2007-08-07 The Regents Of The University Of California Assays for detecting modulators of cytoskeletal function
US6300117B1 (en) * 1997-09-15 2001-10-09 Genencor International, Inc. Proteases from gram-positive organisms
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US7070921B2 (en) 2000-04-28 2006-07-04 Molecular Devices Corporation Molecular modification assays
US6521440B1 (en) * 1997-09-15 2003-02-18 Genencor International, Inc. Proteases from gram-positive organisms
US7632651B2 (en) 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
US7378244B2 (en) * 1997-10-01 2008-05-27 Geron Corporation Telomerase promoters sequences for screening telomerase modulators
WO1999018438A1 (fr) * 1997-10-02 1999-04-15 Aclara Biosciences, Inc. Analyses capillaires impliquant la separation d'especes libres et liees
US6284496B1 (en) 1997-10-03 2001-09-04 University Of South Florida DNA vector for determining the presence of out-of-reading-frame mutations
DE19745001A1 (de) * 1997-10-11 1999-05-06 Evotec Biosystems Ag Verfahren zur Affinitätsmarkierung von Oligo- oder Polymeren
MXPA00003705A (es) 1997-10-17 2002-04-17 Univ South Florida Metodo para diagnosticar y monitorear deficiencias inmunes celulares.
US6607829B1 (en) 1997-11-13 2003-08-19 Massachusetts Institute Of Technology Tellurium-containing nanocrystalline materials
US6322901B1 (en) 1997-11-13 2001-11-27 Massachusetts Institute Of Technology Highly luminescent color-selective nano-crystalline materials
GB9724627D0 (en) 1997-11-20 1998-01-21 Genencor Int Bv Gram positive microorganism formate pathway
GB9724629D0 (en) * 1997-11-20 1998-01-21 Genencor Int Bv Alpha/beta hydrolase-fold enzymes
US6316241B1 (en) * 1997-11-20 2001-11-13 Genencor International, Inc. Alpha/beta hydrolase-fold enzymes
US6306642B1 (en) * 1997-11-24 2001-10-23 Quidel Corporation Enzyme substrate delivery and product registration in one step enzyme immunoassays
US5990479A (en) 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
US6207392B1 (en) * 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
US6699723B1 (en) 1997-11-25 2004-03-02 The Regents Of The University Of California Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
DE19756773A1 (de) 1997-12-19 1999-06-24 Dade Behring Marburg Gmbh Neues Verfahren und Diagnosemittel zur Hämostase-Diagnostik
DE19756782A1 (de) 1997-12-19 1999-06-24 Dade Behring Marburg Gmbh Nachweis und Bestimmung festphasenassoziierter Faktoren
WO1999032886A1 (fr) * 1997-12-23 1999-07-01 Vicam, L.P. Mecanisme de signalisation generique pour detecter des analytes
US6599731B1 (en) 1997-12-30 2003-07-29 Genencor International, Inc. Proteases from gram positive organisms
GB9727470D0 (en) 1997-12-30 1998-02-25 Genencor Int Bv Proteases from gram positive organisms
US6465186B1 (en) * 1997-12-30 2002-10-15 Genecor International, Inc. Proteases from gram positive organisms
US6528255B1 (en) * 1997-12-30 2003-03-04 Genencor International, Inc. Proteases from gram positive organisms
US7687057B2 (en) 1998-01-09 2010-03-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US6780609B1 (en) 1998-10-23 2004-08-24 Genome Therapeutics Corporation High bone mass gene of 1.1q13.3
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
US6673914B1 (en) 1998-01-22 2004-01-06 John Wayne Cancer Institute Human tumor-associated gene
AU770896C (en) 1998-09-29 2006-09-07 Gamida Cell Ltd. Methods of controlling proliferation and differentiation of stem and progenitor cells
US6596501B2 (en) 1998-02-23 2003-07-22 Fred Hutchinson Cancer Research Center Method of diagnosing autoimmune disease
WO1999045124A2 (fr) 1998-03-04 1999-09-10 Genencor International, Inc. Formes modifiees de pullulanase
AU768018C (en) 1998-03-20 2004-09-30 Curators Of The University Of Missouri, The Early pregnancy diagnosis using PAGS (pregnancy- associated glycoproteins)
US8062908B2 (en) * 1999-03-29 2011-11-22 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US6303081B1 (en) * 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
CA2326392A1 (fr) 1998-03-30 1999-10-07 Epitope, Inc. Dispositif de recueil pour dosage de fluides en une seule operation
US6337200B1 (en) * 1998-03-31 2002-01-08 Geron Corporation Human telomerase catalytic subunit variants
EP1095183B1 (fr) * 1998-03-31 2012-02-22 Esoterix Genetic Laboratories, LLC Methodes de diagnostic et de traitement de cancer du poumon
US7715989B2 (en) * 1998-04-03 2010-05-11 Elitech Holding B.V. Systems and methods for predicting oligonucleotide melting temperature (TmS)
US7108968B2 (en) * 1998-04-03 2006-09-19 Affymetrix, Inc. Mycobacterial rpoB sequences
US6683173B2 (en) 1998-04-03 2004-01-27 Epoch Biosciences, Inc. Tm leveling methods
US6949367B1 (en) 1998-04-03 2005-09-27 Epoch Pharmaceuticals, Inc. Modified oligonucleotides for mismatch discrimination
US7045610B2 (en) * 1998-04-03 2006-05-16 Epoch Biosciences, Inc. Modified oligonucleotides for mismatch discrimination
WO1999051702A1 (fr) * 1998-04-08 1999-10-14 Terpetschnig Ewald A Composes luminescents
US20030235846A1 (en) * 1998-04-08 2003-12-25 Terpetschnig Ewald A. Luminescent compounds
US7250517B2 (en) * 1998-04-08 2007-07-31 Ewald A. Terpetschnig Luminescent compounds
US6538129B1 (en) 1999-04-07 2003-03-25 Ewald A. Terpetschnig Luminescent compounds
US7411068B2 (en) * 1998-04-08 2008-08-12 Terpetschnig Ewald A Luminescent compounds
US6872537B1 (en) 1998-04-14 2005-03-29 Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
AU3745799A (en) 1998-04-14 1999-11-01 Regents Of The University Of California, The Assays for the detection of microtubule depolymerization inhibitors
US6699969B1 (en) 1998-04-14 2004-03-02 The Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US20080206206A1 (en) 1998-05-07 2008-08-28 University Of South Florida Bone marrow-derived neuronal cells
US6153442A (en) * 1998-05-20 2000-11-28 Dade Behring Inc. Reagents and methods for specific binding assays
US6303325B1 (en) 1998-05-29 2001-10-16 Dade Behring Inc. Method for detecting analytes
EP1086123A1 (fr) * 1998-06-09 2001-03-28 Immco Diagnostics Technique elisa pour phase en solution
GB9814506D0 (en) * 1998-07-03 1998-09-02 Stanley Christopher J Optical sensor for insitu measurement of analytes
DK1095273T3 (da) 1998-07-03 2006-01-23 Precisense As Biologisk nedbrydelig optisk föler for in situ måling af analytter
USRE38525E1 (en) 1998-07-03 2004-06-08 Torsana Diabetes Diagnostics A/S Optical sensor for in situ measurement of analytes
US6344443B1 (en) 1998-07-08 2002-02-05 University Of South Florida Peptide antagonists of tumor necrosis factor alpha
AU4994899A (en) 1998-07-13 2000-02-01 University Of South Florida Modulation of the phospholipase a2 pathway as a therapeutic
ES2188190T5 (es) 1998-07-21 2007-11-16 Danisco A/S Producto alimentario.
EP1097378A2 (fr) * 1998-07-21 2001-05-09 Burstein Laboratories Inc. Dispositifs de dosage utilisant des disques optiques et methodes correspondantes
EP1018004B1 (fr) 1998-07-22 2006-11-22 Syntron Bioresearch, Inc. Dispositif permettant de deceler differents composants
US6187563B1 (en) 1998-08-07 2001-02-13 Yale University βIV-spectrin-polypeptides and nucleic acids encoding same
SE9803099D0 (sv) 1998-09-13 1998-09-13 Karolinska Innovations Ab Nucleic acid transfer
US6251303B1 (en) 1998-09-18 2001-06-26 Massachusetts Institute Of Technology Water-soluble fluorescent nanocrystals
US6617583B1 (en) 1998-09-18 2003-09-09 Massachusetts Institute Of Technology Inventory control
US6306610B1 (en) 1998-09-18 2001-10-23 Massachusetts Institute Of Technology Biological applications of quantum dots
CA2343979C (fr) 1998-09-21 2011-11-15 Schering Corporation Interleukine humaine b50, ses utilisations therapeutiques
JP4630459B2 (ja) * 1998-09-24 2011-02-09 インディアナ・ユニバーシティ・リサーチ・アンド・テクノロジー・コーポレーション 水溶性発光量子ドットおよびその生体分子コンジュゲート
EP0997476A3 (fr) 1998-09-25 2000-07-19 Schering-Plough Anticorps contre un antigène de cellules Langerhans mammifères et leurs utilisations
US6153411A (en) * 1998-10-30 2000-11-28 American Water Works Company, Inc. Methods and kits for detection of Cryptosporidium parvum using immunomagnetic separation and amplification
AR022236A1 (es) 1999-01-11 2002-09-04 Schering Corp Citoquinas mamiferas purificadas; reactivos y metodos relacionados
US6911201B1 (en) 1999-02-04 2005-06-28 Technion Research & Development Foundation Ltd. Method of producing undifferentiated hemopoietic stem cells using a stationary phase plug-flow bioreactor
US6156515A (en) * 1999-02-09 2000-12-05 Urocor, Inc. Prostate-specific gene for diagnosis, prognosis and management of prostate cancer
EP1942114A3 (fr) 1999-03-11 2008-08-27 Schering Corporation "Cytokines de mammifères ; réactifs et procédés associés"
IL146093A0 (en) 1999-04-20 2002-07-25 Target Discovery Inc Method of separating a polypeptide or protein from a solution containing a plurality thereof
KR101018134B1 (ko) 1999-05-13 2011-02-25 쉐링 코포레이션 Ｏｘ2 수용체 동족체
DK2385124T3 (da) 1999-05-14 2013-11-18 Arbor Vita Corp Peptider, eller peptid-analoger, til modulering af bindingen af et PDZ protein og et PL protein
US6440682B1 (en) * 1999-05-28 2002-08-27 Detroit R&D Inc. Detection of hypertension using immunoreactive metabolic products
US6787318B1 (en) * 1999-06-01 2004-09-07 Roskamp Research Institute, Llc Assay for evaluating the therapeutic effectiveness of agents in reducing Alzheimer's disease pathology
PT1181366E (pt) 1999-06-01 2009-05-25 Schering Corp Proteínas receptoras de mamífero; reagentes e métodos relacionados
US7534605B2 (en) * 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
GB9914210D0 (en) 1999-06-17 1999-08-18 Danisco Promoter
US6262265B1 (en) 1999-06-18 2001-07-17 Microgenics Corporation Non-hydrolyzable analogs of heroin metabolites suitable for use in immunoassay
WO2004006831A2 (fr) * 2002-07-12 2004-01-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methode et dispositif d'induction de processus biologiques par des micro-organismes
EP1374889A1 (fr) * 1999-06-25 2004-01-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Procédé permettant d'induire une angiogénèse au moyen des micro-organes
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
WO2001002374A1 (fr) 1999-07-06 2001-01-11 Surromed, Inc. Colorants fluorescents pontes, leur preparation et leur utilisation dans des dosages
WO2001009176A2 (fr) 1999-07-30 2001-02-08 Schering Corporation Cytokines mammaliennes; reactifs correspondants
US6875582B1 (en) 1999-08-19 2005-04-05 Omniscience Pharmaceuticals, Inc. Methods and targets of antibiotic resistance
US7811981B2 (en) 1999-08-30 2010-10-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
US7101839B1 (en) 1999-08-30 2006-09-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
EP1905832A3 (fr) 1999-09-09 2009-09-09 Schering Corporation Interleukin-12 P40 et interleukin B30 de mammifères, anticorps, utilisation dans des compositions pharmaceutiques
US6998232B1 (en) 1999-09-27 2006-02-14 Quark Biotech, Inc. Methods of diagnosing bladder cancer
US7668658B2 (en) 1999-10-13 2010-02-23 Sequenom, Inc. Methods for generating databases and databases for identifying polymorphic genetic markers
US7030228B1 (en) 1999-11-15 2006-04-18 Miltenyi Biotec Gmbh Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
ES2272333T3 (es) * 1999-11-19 2007-05-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Procedimiento para aumentar el nivel de una sustancia de fermentacion.
EP2275447A1 (fr) 1999-11-24 2011-01-19 Schering Corporation Procedes d'inhibition de metastases
DE60040556D1 (de) 1999-12-06 2008-11-27 Univ Illinois Hochaffine t-zellrezeptorproteine und verfahren
US6544792B1 (en) 1999-12-21 2003-04-08 Genencor International, Inc. Production of secreted polypeptides
EP1111050B1 (fr) * 1999-12-22 2007-03-14 Dade Behring Marburg GmbH Solutions de procalcitonine humaine
EP1110970B1 (fr) 1999-12-22 2008-05-14 Dade Behring Marburg GmbH Anticorps anti-procalcitonin, procédé de production et utilisation
US6544506B2 (en) * 2000-01-05 2003-04-08 Yeda Research & Development Co. Ltd. Veto cells effective in preventing graft rejection and devoid of graft versus host potential
US7230088B2 (en) * 2001-07-03 2007-06-12 Mallinckrodt, Inc. Compounds for dual photodiagnosis and therapy
US7385106B2 (en) * 2000-01-24 2008-06-10 Ramot At Tel Aviv University Ltd. Plants tolerant of environmental stress conditions, methods of generating same and novel polynucleotide sequence utilized thereby
DE10003734A1 (de) * 2000-01-28 2001-08-02 Bosch Gmbh Robert Detektionsverfahren und -vorrichtung
CA2400948A1 (fr) * 2000-02-25 2001-08-30 Ludwig Institute For Cancer Research Materiaux et procedes impliquant un hybride d'adn de facteur de croissance de l'endothelium vasculaire et de proteines
DE60142828D1 (de) 2000-03-01 2010-09-30 Epoch Biosciences Inc Modifizierte oligonukleotide zur unterscheidung von fehlpaarungen
US20040002068A1 (en) 2000-03-01 2004-01-01 Corixa Corporation Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
EP1944310A3 (fr) 2000-03-01 2008-08-06 Epoch Biosciences, Inc. Oligonucléotides modifiées pour discrimination de désadaptation
DE60035127T2 (de) 2000-03-06 2008-02-14 Dade Behring Marburg Gmbh Mit polysacchariden beschichtete träger, deren herstellung und verwendung
US7829313B2 (en) * 2000-03-24 2010-11-09 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
US7875442B2 (en) * 2000-03-24 2011-01-25 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
WO2006053769A1 (fr) 2004-11-18 2006-05-26 Eppendorf Array Technologies Quantification en temps reel de cibles multiples sur un microreseau
US8288128B2 (en) * 2004-11-18 2012-10-16 Eppendorf Array Technologies S.A. Real-time quantification of multiple targets on a micro-array
WO2001072768A2 (fr) 2000-03-27 2001-10-04 Technion Research And Development Foundation Ltd. Complexes majeurs d'histocompatibilite monocatenaires de classe 1, constructions les codant et leurs methodes de production
US20030108927A1 (en) * 2000-04-03 2003-06-12 Kathryn Leishman Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases
ATE416782T1 (de) 2000-04-18 2008-12-15 Schering Corp Medizinische verwendung von il-174 agonisten und antagonisten
IL135884A (en) * 2000-04-30 2005-08-31 Yissum Res Dev Co Method for measuring non-transferrin bound iron
JP4796259B2 (ja) 2000-05-04 2011-10-19 シーメンス・ヘルスケア・ダイアグノスティックス・プロダクツ・ゲーエムベーハー 複数のアナライトの検出において使用するための組成物
US7019129B1 (en) 2000-05-09 2006-03-28 Biosearch Technologies, Inc. Dark quenchers for donor-acceptor energy transfer
DK1287130T3 (da) 2000-05-10 2008-09-01 Schering Corp Cytokinreceptorunderenhedproteiner fra pattedyr, tilhörende reagenser og fremgangsmåder
US7422743B2 (en) 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
IL152725A0 (en) 2000-05-25 2003-06-24 Schering Corp Human receptor proteins, related reagents and methods
WO2005000087A2 (fr) * 2003-06-03 2005-01-06 Chiron Corporation Produits genetiques exprimes de facon differentielle dans des cellules cancereuses du colon et leurs methodes d'utilisation ii
US6936702B2 (en) * 2000-06-07 2005-08-30 Li-Cor, Inc. Charge-switch nucleotides
EP2226330B1 (fr) 2000-06-07 2013-09-18 Pacific Biosciences of California, Inc. Nucléotides à commutation de charge
US7846733B2 (en) 2000-06-26 2010-12-07 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
GB0016841D0 (en) 2000-07-07 2000-08-30 Stanley Christopher J Optical device for measurement of analytes in tears
US6958214B2 (en) * 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
HUP0300810A2 (hu) 2000-07-20 2003-08-28 M.G.V.S. Ltd. Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazása
US20040037828A1 (en) 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
DE60143754D1 (de) 2000-08-08 2011-02-10 Technion Res And Dev Of Foundation Ltd Pharmazeutische zusammensetzungen und methoden nützlich zur behandlung von krebs oder leberfibrose
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
EP1683874A3 (fr) 2000-08-29 2006-10-11 YEDA RESEARCH AND DEVELOPMENT Co. LTD. Méthode pour l'isolement de gènes codant pour des protéines à fonction spécifique et pour le criblage d'agents pharmaceutiques actifs
CA2421200A1 (fr) 2000-09-08 2002-03-14 Board Of Regents, The University Of Texas System Ciblage adenoviral et manipulation de la reponse du systeme immunitaire au moyen de peptides ciblants
MXPA03002049A (es) 2000-09-08 2003-07-24 Schering Corp Genes de mamiferos: reactivos y metodos relacionados.
US6673623B1 (en) 2000-09-12 2004-01-06 Novocure, Inc. Methods and compositions that control lipid production
DK1356060T3 (da) 2000-09-18 2006-05-01 Genencor Int Dobbeltarginintranslokation i Bacillus
US7632522B2 (en) * 2000-09-28 2009-12-15 Nanocyte Inc. Use of stinging cells/capsules for the delivery of active agents to keratinous substances
US20070281037A9 (en) * 2000-09-28 2007-12-06 Nanocyte Inc. Sterile preparations and compositions including stinging capsules and methods of producing and using same
EP1379127B1 (fr) * 2000-09-28 2013-04-17 Nanocyte Inc. Procedes, compositions et dispositifs utilisant des cellules/capsules urticantes pour administrer un agent therapeutique ou cosmetique dans un tissu
US6815164B2 (en) 2000-10-06 2004-11-09 Nugen Technologies, Inc. Methods and probes for detection and/or quantification of nucleic acid sequences
GB0025147D0 (en) 2000-10-13 2000-11-29 Torsana Diabetes Diagnostics A Optical sensor for in situ measurement of analytes
US7045283B2 (en) 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
EP2479578A1 (fr) 2000-10-19 2012-07-25 Target Discovery, Inc. Étiquetage des défauts de masse pour déterminer les séquences d'oligomère
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
IL155940A0 (en) 2000-11-17 2003-12-23 Vascular Biogenics Ltd Promoters exhibiting endothelial cell specificity and method of using same
AU2002218461B2 (en) 2000-11-24 2006-09-07 Vascular Biogenics Ltd Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
WO2002044366A2 (fr) * 2000-11-29 2002-06-06 Lynkeus Biotech Gmbh Nouvelles proteines humaines specifiques de la retine c7orf9, c12orf7, mpp4 et f379
AU2002221013A1 (en) * 2000-11-30 2002-06-11 Yeda Research And Development Co..Ltd. Methods of utilizing cultured non-gvhd inducing t lymphocytes to treat disease
JP2004524010A (ja) 2000-11-30 2004-08-12 モルキューラー スキンケア リミテッド 疾患の診断および処置
AU2002227156A1 (en) 2000-12-01 2002-06-11 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
NO20006130D0 (no) * 2000-12-01 2000-12-01 Erling Sundrehagen Reagens og analysemetode
US20020165149A1 (en) * 2000-12-08 2002-11-07 Kranz David M. Mutated class II major histocompatibility proteins
DE60142709D1 (de) 2000-12-13 2010-09-09 Nugen Technologies Inc Methoden und zusammensetzungen zur generierung einer vielzahl von kopien von nukleinsäuresequenzen und methoden zur detektion derselben
DE10064827A1 (de) * 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
IL157006A0 (en) * 2001-01-17 2004-02-08 Univ Ramot Chitinases, derived from carnivorous plants, polynucleotide sequence encoding thereof, and methods of isolating and using same
GB0101762D0 (en) * 2001-01-23 2001-03-07 Medical Res Council Method
CA2475021A1 (fr) * 2001-01-31 2002-08-08 Dror Mevorach Induction de tolerance par des cellules apoptotiques et/ou necrotiques
US20050202098A1 (en) 2001-01-31 2005-09-15 Tolaren Disease therapy using dying or dead cells
NZ523167A (en) 2001-03-09 2006-08-31 Nugen Technologies Inc Methods, compositions and kits for amplifying RNA sequences of interest which employ an RNA/DNA composite primer
EP1368497A4 (fr) 2001-03-12 2007-08-15 California Inst Of Techn Procedes et appareil d'analyse de sequences de polynucleotide par extension de base asynchrone
WO2002072779A2 (fr) 2001-03-12 2002-09-19 Affymetrix, Inc. Composes de marquage d'acide nucleique
US20030104410A1 (en) * 2001-03-16 2003-06-05 Affymetrix, Inc. Human microarray
US20030003454A1 (en) 2001-03-23 2003-01-02 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Methods and kits for determining a risk to develop cancer, for evaluating an effectiveness and dosage of cancer therapy and for correlating between an activity of a DNA repair enzyme and a cancer
US20030220475A1 (en) * 2001-04-03 2003-11-27 Fields Howard A. Neutralizing immunogenic hev polypepetides
AU2002254524A1 (en) * 2001-04-06 2002-10-21 The Government Of The United States Of America, Represented By The Secretary, Department Of Health A Use of semenogelin in the diagnosis, prognosis and treatment of cancer
ES2284897T3 (es) 2001-05-18 2007-11-16 Danisco A/S Procedimiento para la preparacion de una masa con una enzima.
CA2448142A1 (fr) 2001-05-22 2002-11-28 Merck & Co., Inc. Substrats de beta-secretase et leurs utilisations
US7118907B2 (en) * 2001-06-06 2006-10-10 Li-Cor, Inc. Single molecule detection systems and methods
US6770622B2 (en) 2001-06-08 2004-08-03 Gary A. Jarvis N-terminally truncated galectin-3 for use in treating cancer
US20070190534A1 (en) * 2001-06-11 2007-08-16 Genesis Genomics Inc. Mitochondrial sites and genes associated with prostate cancer
US20030003510A1 (en) * 2001-06-27 2003-01-02 Bray Terry L. Biophotonic sensors and methods of use thereof
JP2005508493A (ja) * 2001-06-28 2005-03-31 アドヴァンスト リサーチ アンド テクノロジー インスティテュート、インコーポレイティッド 多色量子ドット標識ビーズおよびそのコンジュゲートの製造方法
GB0116853D0 (en) 2001-07-10 2001-09-05 Torsana Diabetes Diagnostics A Optical sensor containing particles for in SITU measurement of analytes
MXPA04000397A (es) * 2001-07-19 2004-03-18 Yissum Res Dev Co Polipeptidos que tienen actividad catalitica de isomerasa de carotenoides, acidos nucleicos que los codifican y usos de los mismos.
US20030031627A1 (en) * 2001-07-31 2003-02-13 Mallinckrodt Inc. Internal image antibodies for optical imaging and therapy
ATE481497T1 (de) * 2001-08-01 2010-10-15 Univ Utah Am n-terminus trunkierte isoformen von zyklischen phosphodiesterasen pde3a
US6833441B2 (en) 2001-08-01 2004-12-21 Abmaxis, Inc. Compositions and methods for generating chimeric heteromultimers
US20030082596A1 (en) * 2001-08-08 2003-05-01 Michael Mittmann Methods of genetic analysis of probes: test3
US20060073530A1 (en) * 2001-08-15 2006-04-06 Olaf Schneewind Methods and compositions involving sortase B
WO2003017817A2 (fr) 2001-08-16 2003-03-06 Bar Ilan University Diagnostic, prevention et traitement du cancer
US20040136972A1 (en) 2001-09-07 2004-07-15 Yeda Research And Development Co. Ltd. Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
DE60233744D1 (de) 2001-09-20 2009-10-29 Univ Texas Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper-komplexe mit elisa-tests
US7393696B2 (en) * 2001-09-28 2008-07-01 Aspenbio Pharma, Inc. Bovine pregnancy test
GB0212544D0 (en) * 2002-05-30 2002-07-10 Microsens Biophage Ltd Methods for detection of target molecules and molecular interactions
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US7138370B2 (en) 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
EP2316485A1 (fr) 2001-10-12 2011-05-04 Schering Corporation Composition pour soins personnels
US8323903B2 (en) * 2001-10-12 2012-12-04 Life Technologies Corporation Antibody complexes and methods for immunolabeling
US20050069962A1 (en) 2001-10-12 2005-03-31 Archer Robert M Antibody complexes and methods for immunolabeling
CA2463816C (fr) 2001-10-19 2014-07-08 Vascular Biogenics Ltd. Constructions de polynucleotides, compositions pharmaceutiques et procedes de regulation negative de l'angiogenese et de therapie anticancereuse
US20040054162A1 (en) * 2001-10-30 2004-03-18 Hanna Michelle M. Molecular detection systems utilizing reiterative oligonucleotide synthesis
US7045319B2 (en) 2001-10-30 2006-05-16 Ribomed Biotechnologies, Inc. Molecular detection systems utilizing reiterative oligonucleotide synthesis
US7175983B2 (en) * 2001-11-02 2007-02-13 Abmaxis, Inc. Adapter-directed display systems
DE10153829A1 (de) * 2001-11-05 2003-05-28 Bayer Ag Assay basierend auf dotierten Nanoteilchen
US20030124599A1 (en) * 2001-11-14 2003-07-03 Shiping Chen Biochemical analysis system with combinatorial chemistry applications
MXPA04004880A (es) 2001-11-20 2004-09-03 Monsanto Technology Llc Composiciones y metodos para el diagnostico temprano y preciso de prenez.
US6952704B2 (en) * 2001-11-26 2005-10-04 Microsoft Corporation Extending a directory schema independent of schema modification
US9575070B2 (en) * 2001-12-04 2017-02-21 Wayne State University Neoepitope detection of disease using protein arrays
US8178128B2 (en) * 2001-12-05 2012-05-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Nanoparticles containing polymeric nucleic acid homologs
US20050085432A1 (en) * 2001-12-26 2005-04-21 Aviva Lapidot Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections
IL152904A0 (en) 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
WO2003062404A1 (fr) 2002-01-25 2003-07-31 Gamida-Cell Ltd. Methodes de developpement de cellules souches et de cellules precurseurs, populations de cellules multipliees obtenues a l'aide de ces methodes
US7781396B2 (en) * 2002-01-31 2010-08-24 Tel Aviv University Future Technology Development L.P. Peptides directed for diagnosis and treatment of amyloid-associated disease
US20040052928A1 (en) * 2002-09-06 2004-03-18 Ehud Gazit Peptides and methods using same for diagnosing and treating amyloid-associated diseases
US20030186875A1 (en) 2002-02-01 2003-10-02 Rene De Waal Malefyt Uses of mammalian cytokine; related reagents
US6992176B2 (en) 2002-02-13 2006-01-31 Technion Research & Development Foundation Ltd. Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease
SI1487972T1 (sl) 2002-02-21 2016-03-31 Institute Of Virology Slovak Academy Of Sciences Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe
US7053188B2 (en) 2002-02-22 2006-05-30 Purdue Research Foundation Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase
US7375206B2 (en) 2002-02-22 2008-05-20 The United States Of America As Represented By The Department Of Health And Human Services Brother of the regulator of imprinted sites (BORIS)
WO2003078567A2 (fr) * 2002-03-18 2003-09-25 Gamida-Cell Ltd. Procedes permettant d'induire la differenciation dans des cellules souches expansees ex vivo
US7872048B2 (en) 2004-09-18 2011-01-18 University Of Maryland, Baltimore Methods for treating spinal cord injury with a compound that inhibits a NCCa-ATP channel
DE60320793D1 (de) * 2002-03-26 2008-06-19 Nanocyte Inc Nesselzellen mit expression eines exogenen polynucleotids, das ein therapeutisches, diagnostisches oder kosmetisches mittel kodiert, und diese nesselzellen verwendende verfahren, zusammensetzungen und vorrichtungen oder daraus gewonnene kapseln zur ametischen mittels in ein gewebe
DE10214019A1 (de) * 2002-03-30 2003-10-16 Detlef Mueller-Schulte Lumineszierende, sphärische, nicht autofluoreszierende Silicagel-Partikel mit veränderbaren Emissionsintensitäten und -frequenzen
US7332585B2 (en) 2002-04-05 2008-02-19 The Regents Of The California University Bispecific single chain Fv antibody molecules and methods of use thereof
WO2003087302A2 (fr) 2002-04-12 2003-10-23 Stratagene Nucleotides a double marquage
CA2391438A1 (fr) * 2002-05-01 2003-11-01 Procyon Biopharma Inc. Reactifs et methodes diagnostiques a base de psp94
US7534580B2 (en) * 2002-05-01 2009-05-19 Ambrilia Biopharma Inc. PSP94 diagnostic reagents and assays
CA2483958A1 (fr) * 2002-05-02 2003-11-13 Aspenbio, Inc. Detection de la gravidite
CA2484676A1 (fr) * 2002-05-03 2003-11-13 Sequenom, Inc. Muteines de proteines d'ancrage de kinase, leurs peptides, et procedes associes
US20040121442A1 (en) * 2002-05-05 2004-06-24 Ilan Chet Fungal chitinase, polynucleotide sequences encoding same, promoters of same, and uses thereof
US20050221349A1 (en) * 2002-05-30 2005-10-06 Stuart Wilson Methods of detecting target molecules and molecular interactions
EP1509624A2 (fr) * 2002-05-31 2005-03-02 Secretary, Department Of Atomic Energy Procede de detection d'un acide nucleique cible par une technique met/fret dans lequel le donneur et l'accepteur sont sur des brins complementaires
CA2492631C (fr) * 2002-05-31 2013-03-12 Genetic Technologies Limited Anticorps maternels servant de marqueurs de cellules foetales permettant d'identifier et d'enrichir les cellules foetales du sang maternel
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
SI2269656T1 (sl) 2002-07-15 2014-11-28 Board Of Regents, The University Of Texas System Izbrana protitelesa, ki se veĹľejo na aminofosfolipide, in njihova uporaba v zdravljanju raka
AU2003304195B8 (en) 2002-07-15 2008-08-28 Board Of Regents, The University Of Texas System Combinatorial protein library screening by periplasmic expression
US7794716B2 (en) 2002-07-25 2010-09-14 Glenveigh Pharmaceuticals, Llc Antibody composition and passive immunization against pregnancy-induced hypertension
WO2004012762A2 (fr) 2002-08-01 2004-02-12 Yeda Research And Development Co. Ltd. Methode et composition pour la protection du tissu neuronal contre une lesion induite par des taux de glutamate eleves
CA2495121A1 (fr) * 2002-08-10 2004-02-19 Yale University Antagonistes de recepteur nogo
CN102023220A (zh) 2002-09-09 2011-04-20 生命树股份有限公司 诊断宫颈癌的方法
AU2003278832A1 (en) * 2002-09-13 2004-04-30 Carnegie Mellon University Optical biosensors and methods of use thereof
US20050042621A1 (en) * 2002-09-27 2005-02-24 Affymetrix, Inc. Method for preparing a nucleic acid sample for hybridization to an array
US7267981B2 (en) 2002-10-07 2007-09-11 Technion Research & Development Foundation Ltd. Human foreskin fibroblasts for culturing ES cells
CA2500407C (fr) * 2002-10-11 2009-05-26 Zbx Corporation Dispositifs de diagnostic
JP2006503582A (ja) * 2002-10-21 2006-02-02 ディスカヴァーエックス インコーポレイテッド Ｉｐ３タンパク質結合測定法
CA2501228A1 (fr) 2002-10-24 2004-05-06 Sterix Limited Inhibiteurs de 11-beta-hydroxy steroide dehydrogenase de type 1 et de type 2
US20040146949A1 (en) * 2002-10-25 2004-07-29 Jun Tan Methods and compounds for disruption of CD40R/CD40L signaling in the treatment of alzheimer's disease
WO2004040252A2 (fr) 2002-10-30 2004-05-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Molecules et leurs procedes d'utilisation pour la mesure de fer non lie par la transferrine
US20050054097A1 (en) * 2002-11-17 2005-03-10 Tony Peled EX-VIVO expansion of hematopoietic system cell populations in mononuclear cell cultures
FI20022048A0 (fi) * 2002-11-18 2002-11-18 Valtion Teknillinen Ei-kompetetiivinen immunomääritys pienille analyyteille
JP5271475B2 (ja) 2002-11-26 2013-08-21 ザ ユニヴァーシティー オヴ シカゴ 微生物媒介上皮疾患の予防及び治療のための材料並びに方法
US7947499B2 (en) * 2002-11-29 2011-05-24 Technion Research & Development Foundation Ltd. Method of dynamically culturing embryonic stem cells
EP2031070B1 (fr) 2002-12-04 2013-07-17 Life Technologies Corporation Amplification multiplexe de polynucléotides
US7491699B2 (en) 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
JP4676202B2 (ja) 2002-12-12 2011-04-27 アール．ビー．ティー （ラクト バイオ テクノロジーズ） リミテッド リグニンペルオキシオダーゼの製造方法ならびに皮膚および毛髪の明色化におけるその使用
EP2457999B1 (fr) 2002-12-16 2018-10-17 Technion Research & Development Foundation Ltd. Milieu de culture pour cellules souches pluripotentes
EP1587953B1 (fr) 2003-01-02 2012-02-22 Rappaport Family Institute for Research in the Medical Sciences Methodes de prediction de potentiel a tirer benefice d'un traitement antioxydant pour la prevention de maladies cardiovasculaires chez des patients hyperglycemiques
US20040229245A1 (en) * 2003-01-06 2004-11-18 Anton Bittner Methods and algorithms for performing quality control during gene expression profiling on DNA microarray technology
WO2004060791A1 (fr) 2003-01-07 2004-07-22 Ramot At Tel Aviv University Ltd. Nanostructures de peptides encapsulant une matiere etrangere ainsi que procede de fabrication correspondant
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
MXPA05007653A (es) * 2003-01-17 2005-09-30 Danisco Metodo.
ES2521681T3 (es) 2003-01-17 2014-11-13 Dupont Nutrition Biosciences Aps Método para producir un éster de carbohidrato
US20050014249A1 (en) * 2003-02-21 2005-01-20 Norbert Staimer Chromatographic analysis on optical bio-discs and methods relating thereto
EP1599598A4 (fr) 2003-03-04 2007-08-08 Yeda Res & Dev Polypeptides pon, polynucleotides les codant et compositions et procedes utilisant ces derniers
EP1599608A4 (fr) * 2003-03-05 2007-07-18 Genetic Technologies Ltd Identification d'adn foetal et de marqueurs de cellule foetale dans du plasma ou du serum maternel
AU2004217699B2 (en) * 2003-03-07 2008-07-03 Gamida-Cell Ltd. Expansion of renewable stem cell populations using modulators of PI 3-kinase
CN1777673B (zh) 2003-03-07 2010-04-28 新英格兰医学中心医院有限公司 IgA1沉积疾病的治疗
US8017113B2 (en) 2003-03-12 2011-09-13 Rappaport Family Institute For Research In The Medical Sciences Compositions and methods for diagnosing and treating an inflammation
US7294701B2 (en) * 2003-04-02 2007-11-13 Technion Research & Development Foundation Ltd. Antibody fragment capable of modulating multidrug resistance and compositions and kits and methods using same
WO2004087042A2 (fr) 2003-04-04 2004-10-14 Yeda Research And Development Co. Ltd. Anticorps et compositions pharmaceutiques contenant ces derniers utiles pour inhiber l'activite de metalloproteines
EP1611233B1 (fr) 2003-04-08 2016-01-06 Yeda Research And Development Co., Ltd. Cellules souches presentant une sensibilite accrue au sdf-1 et procedes pour leur obtention et utilisation
FR2853551B1 (fr) 2003-04-09 2006-08-04 Lab Francais Du Fractionnement Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee
CA2521084A1 (fr) 2003-04-14 2004-10-28 Nugen Technologies, Inc. Amplification globale effectuee avec une amorce composite amorcee de maniere aleatoire
KR20060023959A (ko) * 2003-04-16 2006-03-15 예일 유니버시티 아밀로이드 플라크 관련 상태의 치료용 ｎｏｇｏ-수용체길항자
US7917298B1 (en) 2003-04-17 2011-03-29 Nanosys, Inc. Nanocrystal taggants
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
AU2005234725B2 (en) 2003-05-22 2012-02-23 Evogene Ltd. Methods of Increasing Abiotic Stress Tolerance and/or Biomass in Plants and Plants Generated Thereby
US7554007B2 (en) 2003-05-22 2009-06-30 Evogene Ltd. Methods of increasing abiotic stress tolerance and/or biomass in plants
CN101942449B (zh) 2003-05-22 2014-07-02 伊沃基因有限公司 提高植物非生物胁迫耐受性和/或生物量的方法及用该方法所产生的植物
US8129514B2 (en) * 2003-06-19 2012-03-06 Evogene Ltd. Nucleotide sequences for regulating gene expression in plant trichomes and constructs and methods utilizing same
EP1636333A4 (fr) * 2003-06-19 2007-10-24 Evogene Ltd Sequences nucleotidiques pour reguler l'expression genetique chez des trichromes vegetaux, et genes hybrides et procedes dans lesquels elles interviennent
CN101415724B (zh) 2003-06-30 2015-12-02 特拉维夫大学未来科技开发有限公司 肽、抗肽抗体以及用它们来诊断和治疗淀粉样蛋白相关疾病的方法
WO2005006949A2 (fr) * 2003-07-07 2005-01-27 Wagner David H Methodes de prediction du developpement de maladies auto-immunes et traitement associe
US8454566B2 (en) * 2003-07-10 2013-06-04 Medtronic Minimed, Inc. Methods and compositions for the inhibition of biofilms on medical devices
US20090088337A1 (en) * 2003-07-10 2009-04-02 Ronald Gill RET-Based Analyte Detection
WO2005014795A2 (fr) 2003-08-08 2005-02-17 Genenews Inc. Biomarqueurs d'osteoarthrite et leurs utilisations
US20050064479A1 (en) * 2003-08-12 2005-03-24 Affymetrix, Inc. Compounds and methods for post incorporation labeling of nucleic acids
AU2004267383A1 (en) * 2003-08-14 2005-03-03 The Bio Balance Corporation Bacterial strains, compositions including same and probiotic use thereof
EP1651674B1 (fr) 2003-08-14 2010-09-29 Exelixis, Inc. Ups utilises comme modificateurs de la voie de la beta catenine et leurs procedes d'utilisation
DE602004030586D1 (de) 2003-09-15 2011-01-27 Oklahoma Med Res Found Verfahren zur verwendung von cytokintests zur diagnose, behandlung und beurteilung von ankyloider spondylitis
US7282339B2 (en) * 2003-09-17 2007-10-16 Invitrogen Corporation Competitive immunoassay
US20050064435A1 (en) * 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
WO2005031362A2 (fr) 2003-10-02 2005-04-07 Ramot At Tel Aviv University Ltd. Nouveaux agents antibacteriens et procedes permettant de les identifier et de les utiliser
IL158287A0 (en) 2003-10-07 2004-05-12 Yeda Res & Dev Antibodies to nik, their preparation and use
AU2004278175B2 (en) 2003-10-07 2010-11-04 Yeda Research And Development Co. Ltd. Antibodies to NIK, their preparation and use
MXPA06004537A (es) * 2003-10-23 2006-06-23 Pfizer Prod Inc Vacuna para la enfermedad periodontal.
US20050227251A1 (en) 2003-10-23 2005-10-13 Robert Darnell Method of purifying RNA binding protein-RNA complexes
AU2004286265A1 (en) * 2003-10-29 2005-05-12 Ribomed Biotechnologies, Inc. Compositions, methods and detection technologies for reiterative oligonucleotide synthesis
PE20090047A1 (es) 2003-11-10 2009-01-26 Schering Corp Anticuerpo recombinante humanizado anti-interleuquina 10
US7169560B2 (en) * 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
JP3615752B1 (ja) 2003-11-18 2005-02-02 淳 高橋 細径樹脂捩じりブラシ
US8034340B2 (en) 2003-11-30 2011-10-11 Yeda Research And Development Ltd. Method for treating an immune disorder by decreasing NIK-SIVA complex formation
US20050118727A1 (en) * 2003-12-01 2005-06-02 Carsten Schelp Conjugates and their use in detection methods
EP1695083A1 (fr) 2003-12-01 2006-08-30 Dade Behring Marburg GmbH Procede de detection homogene
US8039642B2 (en) 2003-12-09 2011-10-18 Life Technologies Corporation Pyrenyloxysulfonic acid fluorescent agents
WO2005064336A1 (fr) * 2003-12-09 2005-07-14 Molecular Probes, Inc. Reactif fluorescent a base d'acide pyrenyloxysulfonique
WO2005059100A2 (fr) * 2003-12-12 2005-06-30 New York University Procedes et compositions se rapportant a la cystatine c
US20100221233A1 (en) * 2003-12-15 2010-09-02 University Of South Florida Compositions and methods for enhancing neuroprotection via administration of stem cells and blood brain barrier permeabilizers
US6991911B2 (en) 2003-12-15 2006-01-31 Dade Behring Inc. Assay for entactogens
US7022492B2 (en) 2003-12-15 2006-04-04 Dade Behring Inc. Ecstasy haptens and immunogens
DK1722834T3 (da) 2003-12-22 2012-10-22 Regentis Biomaterials Ltd Matrix, som omfatter naturligt forekommende tværbundet proteinskelet
EP1708745B1 (fr) 2003-12-23 2012-04-18 Arbor Vita Corporation Anticorps pour des souches oncogenes du hpv et leurs methodes d'utilisation
US7718408B2 (en) * 2003-12-24 2010-05-18 Danisco A/S Method
BRPI0417533B1 (pt) 2003-12-24 2016-03-01 Danisco enzima variante glicolipídio aciltransferase, uso e método para sua produção, método para o preparo de um produto alimentício e produto assado de farinha, processo de refinamento enzimático
GB0716126D0 (en) * 2007-08-17 2007-09-26 Danisco Process
US8007847B2 (en) 2004-01-13 2011-08-30 Eytan Biderman Feeding formula appliance
US7423139B2 (en) * 2004-01-20 2008-09-09 Insight Biopharmaceuticals Ltd. High level expression of recombinant human erythropoietin having a modified 5′-UTR
US20050186646A1 (en) * 2004-01-26 2005-08-25 Cruz Miguel A. Rapid assay to detect ADAMTS-13 activity
WO2005071058A2 (fr) * 2004-01-27 2005-08-04 Compugen Ltd. Procedes et systemes pour l'annotation de sequences de biomolecules
US20070178462A1 (en) * 2004-02-18 2007-08-02 Uebele Victor N Nucleic acid molecules encoding novel murine low-voltage activated calcium channel proteins, designated-alpha1h, encoded proteins and methods of use thereof
EP1716254B1 (fr) 2004-02-19 2010-04-07 Helicos Biosciences Corporation Procedes pour analyser des sequences de polynucleotides
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
EP2208797A3 (fr) 2004-03-01 2010-11-24 Applied Biosystems, LLC Techniques, compositions et kits d'amplification de polynucleotide
EP3006039B1 (fr) 2004-03-02 2021-01-06 Acceleron Pharma Inc. Alk7 polypeptides pour stimuler la perte de graisse
US8352031B2 (en) 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
KR20070062945A (ko) * 2004-04-20 2007-06-18 더 유니버서티 오브 시카고 고분자량의 ｐｅｇ-유사 화합물을 포함하는 치료학적수송 시스템
WO2006083269A2 (fr) * 2004-05-14 2006-08-10 Florida Atlantic University Nanocapteurs luminescents
US8586294B2 (en) 2004-05-18 2013-11-19 The Board Of Trustees Of The Leland Stanford Junior University Detection of protein translocation by beta-galactosidase reporter fragment complementation
US7476734B2 (en) 2005-12-06 2009-01-13 Helicos Biosciences Corporation Nucleotide analogs
ATE507305T1 (de) 2004-05-25 2011-05-15 Helicos Biosciences Corp Verfahren zur nukleinsäureimmobilisierung
WO2005118864A2 (fr) 2004-05-28 2005-12-15 Agensys, Inc. Anticorps et molecules apparentees qui se lient aux proteines d'antigene des cellules souches de prostate (proteines de psca)
CA2877145C (fr) 2004-06-14 2020-03-24 Evogene Ltd. Polynucleotides et polypeptides impliques dans le developpement de la fibre vegetale et procedes permettant de les utiliser
US8034553B2 (en) 2004-06-24 2011-10-11 Kimberly-Clark Worldwide, Inc. Biomarkers for wound healing
JP4796059B2 (ja) * 2004-06-30 2011-10-19 ディスカヴァーエックス コーポレイション 細胞内修飾の分析
US8680062B2 (en) * 2004-07-06 2014-03-25 Deliversir Ltd. System for delivering therapeutic agents into living cells and cells nuclei
WO2006010038A2 (fr) * 2004-07-08 2006-01-26 Biosearch Technologies, Inc. Essai de fluorescence inductible
WO2006006172A2 (fr) * 2004-07-15 2006-01-19 Ramot At Tel Aviv University Ltd. Utilisation d'agents anti-amyloides pour traiter et determiner des infections pathogenes
MX2007000627A (es) 2004-07-16 2007-06-25 Danisco Metodo enzimatico de desgomado de aceite.
CA2579790A1 (fr) * 2004-07-30 2006-02-09 Mount Sinai School Of Medicine Of New York University Inhibiteurs de npc1l1 et npc1l1 et procedes d'utilisation associes
US20060073168A1 (en) * 2004-08-11 2006-04-06 Stephens David S Neisseria meningitidis serogroup a capsular polysaccharide acetyltransferase, methods and compositions
DE102005026163A1 (de) * 2004-08-24 2006-03-02 Dade Behring Marburg Gmbh Gegen den Marburg I Polymorphismus der Faktor VII aktivierenden Protease (FSAP) gerichtete Antikörper, ihre Herstellung und Verwendung
MX2007002294A (es) 2004-08-26 2007-10-19 Engeneic Molecular Delivery Pty Ltd Suministro de acidos nucleicos funcionales a celulas mamiferas via minicelulas intactas, derivadas bacterialmente.
FI20050753A7 (fi) 2004-09-03 2006-03-04 Licentia Oy Uudet peptidit
DE602005021525D1 (de) 2004-09-14 2010-07-08 Univ Colorado R behandlung mit bucindolol
WO2006030442A2 (fr) 2004-09-16 2006-03-23 Gamida-Cell Ltd. Methodes de culture ex vivo de cellules souches et de precurseur par co-culture avec des cellules mesenchymales
CN101043891A (zh) 2004-09-18 2007-09-26 巴尔的摩马里兰大学 靶向NCCa－ATP通道的治疗剂及其使用方法
EP1797127B1 (fr) 2004-09-24 2017-06-14 Amgen Inc. Molecules fc modifiees
US20060067889A1 (en) * 2004-09-27 2006-03-30 Light Sciences Corporation Singlet oxygen photosensitizers activated by target binding enhancing the selectivity of targeted PDT agents
ATE479762T1 (de) 2004-09-29 2010-09-15 Collplant Ltd Kollagenproduzierende pflanzen sowie verfahren zu deren erzeugung und verwendung
WO2006035439A2 (fr) * 2004-09-29 2006-04-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Rnase t2 humaine recombinee et utilisations associees
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
US7390489B2 (en) * 2004-10-08 2008-06-24 Komed Co., Ltd. Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody
US7781402B2 (en) * 2004-10-12 2010-08-24 Closed Loop Therapies Ltd. Methods and implantable devices for treating supraventricular arrhythmias
GB0423139D0 (en) 2004-10-18 2004-11-17 Danisco Enzymes
CA2589034C (fr) * 2004-11-02 2016-05-31 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Compositions et procedes pour traiter des etats hyperproliferatifs
GB0424940D0 (en) 2004-11-11 2004-12-15 Danisco Transcription factors
WO2006055635A2 (fr) * 2004-11-15 2006-05-26 Mount Sinai School Of Medicine Of New York University Compositions et methodes de modification de la signalisation autocrine wnt
IL165484A0 (en) 2004-11-30 2006-01-15 Applied Research Systems Production of proteins
JP2008521907A (ja) 2004-12-03 2008-06-26 シェーリング コーポレイション 抗ｉｇｆ１ｒ治療について患者を予め選択するためのバイオマーカー
US7504769B2 (en) * 2004-12-16 2009-03-17 E. I. Du Pont De Nemours + Company Aromatic chalcogen compounds and their use
US20060134680A1 (en) * 2004-12-22 2006-06-22 Alexander Kotlyar Homogeneous populations of nucleic acids, methods of synthesyzing same and uses thereof
US7220549B2 (en) * 2004-12-30 2007-05-22 Helicos Biosciences Corporation Stabilizing a nucleic acid for nucleic acid sequencing
US8375327B2 (en) 2005-01-16 2013-02-12 Zlango Ltd. Iconic communication
US8019818B2 (en) 2005-01-18 2011-09-13 Zlango Ltd. Communications network system and methods for using same
US7482120B2 (en) 2005-01-28 2009-01-27 Helicos Biosciences Corporation Methods and compositions for improving fidelity in a nucleic acid synthesis reaction
ES2562406T3 (es) 2005-01-31 2016-03-04 Realbio Technologies Ltd. Dispositivo capilar de flujo lateral de reacción multietapa
JP5265923B2 (ja) 2005-02-07 2013-08-14 ジーンニュース インコーポレーテッド 軽度の変形性関節症のバイオマーカーおよびその使用
WO2006087722A1 (fr) 2005-02-17 2006-08-24 Hadasit Medical Research Services And Development Ltd. Bisphosphonates pour le traitement de l'endometriose
GB0503546D0 (en) * 2005-02-21 2005-03-30 Hellenic Pasteur Inst Antibody
EP1871402B1 (fr) 2005-02-25 2017-07-26 State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (A.R.O.), Volcani Center Culture de cellules de grain de raisin pour le traitment de l'inflammation
US7695927B2 (en) * 2005-03-18 2010-04-13 Detroit R & D Detection of hypertension using glucuronidated metabolic products
RU2413735C2 (ru) 2005-03-31 2011-03-10 Эдженсис, Инк. Антитела и родственные молекулы, связывающиеся с белками 161p2f10b
ES2536915T5 (es) 2005-04-04 2023-03-01 Biogen Ma Inc Métodos y productos para evaluar una respuesta inmunitaria a una proteína terapéutica
US20090068207A1 (en) * 2005-04-15 2009-03-12 Vascular Biogenics Ltd. Compositions Containing Beta 2-Glycoprotein I-Derived Peptides for the Prevention and/or Treatment of Vascular Disease
US20130022979A1 (en) 2005-04-18 2013-01-24 Genesis Genomics Inc. 3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER
DE602006017534D1 (de) 2005-04-18 2010-11-25 Mitomics Inc Mitochondriale mutationen und umlagerungen als diagnostisches werkzeug zum nachweis von sonneneinstrahlung, prostatakrebs und anderen krebserkrankungen
US8834862B2 (en) * 2005-04-19 2014-09-16 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent
US7189582B2 (en) 2005-04-27 2007-03-13 Dade Behring Inc. Compositions and methods for detection of sirolimus
DE102005022047A1 (de) 2005-05-09 2006-11-30 Dade Behring Marburg Gmbh Bindungspartner des Plazentalen Wachstumsfaktors insbesondere gegen den Plazentalen Wachstumsfaktor gerichtete Antikörper, ihre Herstellung und Verwendung
WO2006126208A2 (fr) 2005-05-26 2006-11-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions et methodes d'utilisation desdites compositions dans l'administration d'agents dans un organe cible protege par une barriere sanguine
US20070021433A1 (en) 2005-06-03 2007-01-25 Jian-Qiang Fan Pharmacological chaperones for treating obesity
WO2006134602A2 (fr) 2005-06-16 2006-12-21 Ramot At Tel Aviv University Ltd. Cellules isolees et populations comprenant ces cellules pour le traitement de maladies du snc
ES2511218T5 (es) 2005-06-20 2017-12-07 Advanced Cell Diagnostics, Inc. Kits y productos para detección de ácidos nucleicos en células individuales y para identificación de células raras en grandes poblaciones de células heterogéneas
US20070225242A1 (en) * 2005-06-21 2007-09-27 The Board Of Trustees Of The Leland Stanford Junior University Method and composition for treating and preventing tumor metastasis in vivo
US7695975B2 (en) 2005-06-23 2010-04-13 Siemens Healthcare Diagnostics Inc. Detection of adulterated samples
US9051379B2 (en) 2005-07-07 2015-06-09 Fulcrum Sp Ltd. Sp1 polypeptides, modified Sp1 polypeptides and uses thereof
EP1915448B1 (fr) 2005-07-07 2013-09-04 Yissum Research Development Company, of The Hebrew University of Jerusalem Agents de type acide nucléique pour la régulation à la baisse de h19 et méthodes d'emploi desdits agents
EP2484768A3 (fr) 2005-07-18 2012-11-21 Protalix Ltd. Administration mucosale ou enterale de macromolecules biologiquement actives
JP2009504659A (ja) * 2005-08-08 2009-02-05 オンコノン・リミテッド・ライアビリティ・カンパニー 抗体組成物、腫瘍性疾患の処置方法、および受胎能の調節方法
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
WO2007023491A2 (fr) 2005-08-24 2007-03-01 Yeda Research And Development Co. Ltd. Cellules tolerogeniques derivees de donneurs universels et destinees a induire une tolerance a la transplantation non syngenique
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
AU2006286149B2 (en) 2005-08-29 2012-09-13 Technion Research And Development Foundation Ltd. Media for culturing stem cells
LT1931710T (lt) 2005-08-31 2017-03-27 Merck Sharp & Dohme Corp. Rekombinantiniai anti-il-23 antikūnai
WO2007030759A2 (fr) 2005-09-07 2007-03-15 Nugen Technologies, Inc. Procedure d'amplication d'acide nucleique amelioree
US7608395B2 (en) 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
ATE466079T1 (de) 2005-09-22 2010-05-15 Yissum Res Dev Co Nukleinsäure konstrukten, pharmazeutische kompositionen und methoden für die behandlung von krebs
JP2009510198A (ja) * 2005-09-26 2009-03-12 インヴィトロジェン コーポレーション 紫色レーザー励起性色素及びその使用方法
WO2007041340A2 (fr) * 2005-09-30 2007-04-12 The Trustees Of Columbia University In The City Of New York Cellules microfluidiques a arrangements paralleles de molecules d'adn individuelles
US20070202515A1 (en) * 2005-10-12 2007-08-30 Pathologica, Llc. Promac signature application
US20070087437A1 (en) * 2005-10-14 2007-04-19 Jifan Hu Methods for rejuvenating cells in vitro and in vivo
EP1945816B1 (fr) 2005-10-21 2011-07-27 GeneNews Inc. Procédé et appareil permettant de mettre des niveaux de produits de biomarqueurs en correlation avec une maladie
CN101505587A (zh) 2005-10-24 2009-08-12 伊沃基因有限公司 分离的多肽、编码其的多核苷酸、表达其的转基因植物和使用其的方法
US20070105160A1 (en) * 2005-10-24 2007-05-10 Discoverx Detection of intracellular enzyme complex
US7842823B2 (en) * 2005-10-27 2010-11-30 The Regents Of The University Of California Fluorogenic probes for reactive oxygen species
EP2395012B8 (fr) 2005-11-02 2018-06-06 Arbutus Biopharma Corporation Molécules d'ARNsi modifiées et leurs utilisations
UA94922C2 (ru) 2005-11-07 2011-06-25 Зе Скріпс Рісьорч Інстітьют Способ регулирования специфичности сигнализации тканевого фактора у млекопитающего, которое нуждается в этом, способ идентификации агента, который специфически ингибирует сигнализацию тканевого фактора
US8124351B2 (en) 2005-11-18 2012-02-28 Board Of Regents, The University Of Texas System Quantification of fusion proteins and their activity from chromosomal translocation
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
KR20080072748A (ko) 2005-11-29 2008-08-06 가미다-셀 리미티드 줄기세포 귀소 및 생착을 향상시키는 방법
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
US9056291B2 (en) 2005-11-30 2015-06-16 Micronics, Inc. Microfluidic reactor system
RU2008127252A (ru) 2005-12-08 2010-01-20 Новартис АГ (CH) Эффекты ингибиторов fgfr3 на транскрипцию генов
US20070134814A1 (en) * 2005-12-09 2007-06-14 Kajander E O Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease
EP2674440B1 (fr) 2005-12-16 2019-07-03 IBC Pharmaceuticals, Inc. Ensembles bioactifs à base d'immunoglobuline multivalent
SG163525A1 (en) 2005-12-23 2010-08-30 Partnership & Corp Technology Synthetic peptides for use as inhibitors of neurotransmitter secretion and as inducers of muscle relaxation
US7465544B2 (en) * 2006-01-11 2008-12-16 Wisconsin Alumni Research Foundation Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use
WO2007080559A2 (fr) 2006-01-16 2007-07-19 Zlango Ltd. Communication iconique
CA2640423C (fr) 2006-01-27 2016-03-15 Biogen Idec Ma Inc. Antagonistes des recepteurs nogo
TW200738752A (en) 2006-01-31 2007-10-16 Bayer Schering Pharma Ag Modulation of MDL-1 activity for treatment of inflammatory disease
US9249407B2 (en) 2006-02-03 2016-02-02 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US20150038413A1 (en) 2006-02-03 2015-02-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US8476234B2 (en) 2006-02-03 2013-07-02 Prolor Biotech Inc. Long-acting coagulation factors and methods of producing same
US10221228B2 (en) 2006-02-03 2019-03-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US7553940B2 (en) 2006-02-03 2009-06-30 Modigene Inc Long-acting EPO polypeptides and derivatives thereof and methods thereof
US8048849B2 (en) 2006-02-03 2011-11-01 Modigene, Inc. Long-acting polypeptides and methods of producing same
US10351615B2 (en) 2006-02-03 2019-07-16 Opko Biologics Ltd. Methods of treatment with long-acting growth hormone
US8946155B2 (en) 2006-02-03 2015-02-03 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US8759292B2 (en) 2006-02-03 2014-06-24 Prolor Biotech, Llc Long-acting coagulation factors and methods of producing same
US9458444B2 (en) 2006-02-03 2016-10-04 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US8048848B2 (en) 2006-02-03 2011-11-01 Prolor Biotech Ltd. Long-acting interferons and derivatives thereof and methods thereof
US8450269B2 (en) 2006-02-03 2013-05-28 Prolor Biotech Ltd. Long-acting growth hormone and methods of producing same
US20140113860A1 (en) 2006-02-03 2014-04-24 Prolor Biotech Ltd. Long-acting polypeptides and methods of producing and administering same
WO2007091254A1 (fr) 2006-02-06 2007-08-16 Rappaport Family Institute For Research In The Medical Sciences Méthodes et trousse pour le diagnostic du diabète de type 1
ES2700048T3 (es) 2006-02-08 2019-02-13 Genzyme Corp Terapia génica par la enfermedad de Niemann-Pick tipo A
HUE047230T2 (hu) 2006-02-28 2020-04-28 Biogen Ma Inc Gyulladásos és autoimmun betegségek natalizumabbal való kezelésének módszerei
EP4582099A3 (fr) 2006-03-03 2025-10-01 Biogen MA Inc. Procédés de traitement de maladies inflammatoires et auto-immunes avec du natalizumab
CA2641954C (fr) 2006-03-06 2016-04-26 Zetiq Technologies Ltd. Procedes et compositions pour identifier un phenotype cellulaire
US7397546B2 (en) 2006-03-08 2008-07-08 Helicos Biosciences Corporation Systems and methods for reducing detected intensity non-uniformity in a laser beam
WO2007109733A2 (fr) 2006-03-21 2007-09-27 The Johns Hopkins University Marqueurs de diagnostic et de pronostic et strategies de traitement de la sclerose en plaques
EP2010647A4 (fr) 2006-03-23 2010-05-19 Pluristem Ltd Procédés de développement cellulaire et utilisations thérapeutiques des cellules et des milieux conditionnés produits de cette maniere
WO2007110869A2 (fr) 2006-03-28 2007-10-04 Tel Hashomer Medical Research Infrastructure And Services Ltd. Procedes et kits pour determiner la predisposition a la resistance a la warfarine
US20070232556A1 (en) * 2006-03-31 2007-10-04 Montine Thomas J Methods and compositions for the treatment of neurological diseases and disorders
EP2010567A2 (fr) * 2006-04-07 2009-01-07 The Government of the United States of America as Represented by The Department of Health and Human Services Compositions d'anticorps et méthodes de traitement d'une maladie néoplasique
US8841134B2 (en) * 2006-04-10 2014-09-23 Bruker Biospin Corporation Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications
US20070281363A1 (en) * 2006-04-13 2007-12-06 Ewald Terpetschnig Luminescent compounds
FR2900341B1 (fr) * 2006-04-27 2012-09-14 Centre Nat Rech Scient Utilisation de ligands synthetiques multivalents de la nucleoline de surface pour le traitement du cancer
JP2009536739A (ja) * 2006-05-09 2009-10-15 エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント プロテアーゼおよびプロテアーゼ阻害剤の血漿プロファイリングによる拡張期心不全の検出
US7799534B2 (en) * 2006-05-09 2010-09-21 Beckman Coulter, Inc. Nonseparation assay methods
US7732153B2 (en) 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
US20100196336A1 (en) 2006-05-23 2010-08-05 Dongsu Park Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
US20080076188A1 (en) * 2006-06-19 2008-03-27 Patsenker Leonid D Luminescent compounds
EP2041573B1 (fr) * 2006-06-23 2019-09-04 PerkinElmer Health Sciences, Inc. Procédés et dispositifs destinés à des dosages immunologiques microfluidiques pratiqués au point de service
US20090092967A1 (en) * 2006-06-26 2009-04-09 Epoch Biosciences, Inc. Method for generating target nucleic acid sequences
CN101505795B (zh) 2006-07-03 2013-02-13 查尔斯·戴维·阿代尔 用于调节细胞粘附分子表达的组合物
WO2008008797A2 (fr) 2006-07-10 2008-01-17 The Regents Of The University Of California Chélate luminescent de 1-hydroxy-2-pyridinone et de lanthanides
US20080026394A1 (en) * 2006-07-11 2008-01-31 Antara Biosciences Inc. Methods of detecting one or more cancer markers
MX2009000059A (es) * 2006-07-11 2009-04-28 Musc Found For Res Dev Prediccion de falla del corazon despues del infarto al miocardio mediante el perfil de la proteasa y el inhibidor de proteasa.
WO2008010934A2 (fr) 2006-07-14 2008-01-24 Chemocentryx, Inc. Triazolyle phényle benzènesulfonamides
EP2046109A4 (fr) 2006-07-20 2010-01-06 Yeda Res & Dev Organismes photosynthetiques, compositions et procedes de generation desdits organismes
WO2008021954A2 (fr) * 2006-08-09 2008-02-21 Biogen Idec Ma Inc. Procédé de distribution d'un médicament
AU2007321881B2 (en) 2006-08-15 2012-11-01 The Regents Of The University Of California Luminescent macrocyclic lanthanide complexes
JP2008043332A (ja) 2006-08-17 2008-02-28 Panomics Inc 組織スライドからの核酸定量
US20100292090A1 (en) 2006-08-25 2010-11-18 Oncotherapy Science, Inc. Prognostic markers and therapeutic targets for lung cancer
US8809052B2 (en) 2006-08-28 2014-08-19 Yeda Research And Development Co. Ltd. Methods of generating mature oligodendrocytes
US7951776B2 (en) 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
JP2008111824A (ja) * 2006-09-01 2008-05-15 Nox Technologies Inc 腫瘍特異的ｔＮＯＸアイソフォーム及び方法
US7985542B2 (en) * 2006-09-07 2011-07-26 Institut Pasteur Genomic morse code
EP2469283B1 (fr) 2006-09-08 2014-01-15 The Chancellor, Masters and Scholars of the University of Oxford Diagnostic clinique de la fibrose hépatique utilisant le biomarqueur APOL1 du sérum humain
US7569396B1 (en) 2006-09-08 2009-08-04 Purplecow Llc Caffeine detection using internally referenced competitive assays
US8055034B2 (en) * 2006-09-13 2011-11-08 Fluidigm Corporation Methods and systems for image processing of microfluidic devices
US8050516B2 (en) * 2006-09-13 2011-11-01 Fluidigm Corporation Methods and systems for determining a baseline during image processing
ES2426754T3 (es) 2006-10-05 2013-10-25 Technion Research & Development Foundation Ltd. Microtubos y métodos para producirlos
US7888059B2 (en) * 2006-10-05 2011-02-15 Yeda Research And Development Co. Ltd. Highly purified and stabilized Na,K-ATPase isoforms and methods of producing same
US20100222228A1 (en) * 2006-10-11 2010-09-02 Janssen Pharmaceutica N.V. Compositions and methods for treating and diagnosing irritable bowel syndrome
EP1912067A1 (fr) * 2006-10-12 2008-04-16 Eppendorf Array Technologies S.A. Procédé de quantification d'un composé cible issu d'un échantillon biologique à l'aide de puces à microreseau
WO2008051491A2 (fr) 2006-10-20 2008-05-02 Danisco Us, Inc. Genencor Division Polyol oxydases
CA2667012A1 (fr) * 2006-10-26 2008-05-02 Abbott Laboratories Analyse immunologique d'analytes dans des echantillons contenant des anticorps anti-analytes endogenes
US7776605B2 (en) 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
US20080305512A1 (en) * 2006-10-26 2008-12-11 Mattingly Phillip G Assay for cardiac troponin autoantibodies
EP2407783A1 (fr) 2006-10-27 2012-01-18 Janssen Pharmaceutica, N.V. Procédé de profilage pharmacologique de composés
EP2450456A3 (fr) 2006-11-02 2012-08-01 Yale University Evaluation de la compétence d'oocyte
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
EP2102239B1 (fr) 2006-11-30 2012-04-25 Research Development Foundation Bibliothèques d'immunoglobulines améliorées
US8473216B2 (en) * 2006-11-30 2013-06-25 Fluidigm Corporation Method and program for performing baseline correction of amplification curves in a PCR experiment
KR20090088950A (ko) 2006-12-14 2009-08-20 쉐링 코포레이션 가공된 항-ｔｓｌｐ 항체
EP2383345B1 (fr) * 2006-12-20 2017-11-22 Evogene Ltd. Polynucléotides et polypeptides impliqués dans le développement de fibres végétales et procédés d'utilisation
WO2008085895A2 (fr) * 2007-01-04 2008-07-17 Musc Foundation For Research Development Prédiction de la récurrence de fibrillation atriale par profilage de protéase et d'inhibiteur de protéase
ES2634266T3 (es) * 2007-01-11 2017-09-27 Erasmus University Medical Center Captura de conformación cromosómica circular (4C)
EP2111224B1 (fr) 2007-01-12 2016-07-13 University of Maryland, Baltimore Ciblage de canal ncca-atp destiné à protéger les organes après un épisode ischémique
EP2111449B1 (fr) * 2007-01-16 2012-03-07 Yissum Research Development Company of the Hebrew University of Jerusalem Agents nucléotidiques de silençage de h19 destinés au traitement de l'arthrite rhumatoïde
JP5124593B2 (ja) 2007-01-25 2013-01-23 デュポン ニュートリション バイオサイエンシーズ エーピーエス 形質転換バチルス・リケニフォルミス細胞からの脂質アシルトランスフェラーゼの製造
ES2378490T3 (es) 2007-01-26 2012-04-13 University Of Louisville Research Foundation, Inc. Métodos de detección de autoanticuerpos para diagnosticar y caracterizar trastornos
WO2008093331A1 (fr) * 2007-01-29 2008-08-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Conjugues d'anticorps pour vaincre la multiresistances aux medicaments
US8911996B2 (en) 2007-01-31 2014-12-16 Technion Research & Development Foundation Limited Electrospun scaffolds and methods of generating and using same
EP2478924A1 (fr) 2007-02-01 2012-07-25 Technion Research & Development Foundation Fibres et tissus d'albumine et leurs procédés de génération et d'utilisation
TW201307390A (zh) 2007-02-02 2013-02-16 Amgen Inc 海帕西啶（ｈｅｐｃｉｄｉｎ）、海帕西啶拮抗劑及使用方法
US7751863B2 (en) 2007-02-06 2010-07-06 Glumetrics, Inc. Optical determination of ph and glucose
EP2120680A2 (fr) 2007-02-06 2009-11-25 Glumetrics, Inc. Systèmes et procédés optiques pour la mesure ratiométrique de la concentration en glucose dans le sang
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
KR100855299B1 (ko) * 2007-02-16 2008-08-29 건국대학교 산학협력단 인간 ｉｌ-32 특이 항원결정기를 갖는 단일클론항체,특이항체분비 융합 세포주 및 항체들을 이용한 ｉｌ-32측정법
RS58098B1 (sr) 2007-02-23 2019-02-28 Merck Sharp & Dohme Anti-il-23p19 antitela proizvedena genetičkim inženjerstvom
MX2009009080A (es) 2007-02-23 2009-11-02 Schering Corp Anticuerpos anti-interleucina-23p19 manipulados por ingenieria genetica.
WO2008106134A2 (fr) 2007-02-28 2008-09-04 Schering Corporation Anticorps anti-il-23r modifiés
US8748371B2 (en) 2007-02-28 2014-06-10 Yeda Research And Development Co. Ltd. Nuclear targeting sequences
EP2136843A1 (fr) 2007-03-12 2009-12-30 Miraculins Inc. Biomarqueurs du cancer de la prostate et utilisations de ceux-ci
AU2008234530B2 (en) 2007-03-29 2013-03-28 Technion Research & Development Foundation Ltd. Antibodies, methods and kits for diagnosing and treating melanoma
EP2865755B1 (fr) 2007-03-30 2017-02-01 EnGeneIC Molecular Delivery Pty Ltd ARN régulateurs englobant des minicellules intactes, dérivés de bactéries
WO2008120216A1 (fr) 2007-04-02 2008-10-09 Ramot At Tel Aviv University Ltd. Procédés permettant de détecter des cellules cancéreuses et leur utilisation pour diagnostiquer et surveiller le traitement de la maladie
CA2682299C (fr) 2007-04-06 2015-12-22 Becton, Dickinson And Company Compositions et procedes pour l'identification d'un gene de carbapenemase
BRPI0809796B1 (pt) 2007-04-09 2021-09-08 Evogene Ltd Métodos para aumentar o teor de óleo, taxa de crescimento, biomassa, vigor e/ou rendimento de uma planta, e para produzir óleo
WO2008127710A2 (fr) 2007-04-13 2008-10-23 Dana Farber Cancer Institute Méthodes de traitement d'un cancer résistant à des agents thérapeutiques anti-erbb
US8003314B2 (en) 2007-04-16 2011-08-23 Diagnostic Hybrids, Inc. Methods for direct fluorescent antibody virus detection in liquids
ES2516827T3 (es) * 2007-04-23 2014-10-31 Deliversir Ltd Un sistema para entregar agentes terapéuticos a células vivas y núcleos de células
US9556210B2 (en) 2007-04-23 2017-01-31 Sabag-Rfa Ltd. System for delivering therapeutic agents into living cells and cells nuclei
WO2014064687A1 (fr) 2012-10-22 2014-05-01 Deliversir Ltd Système d'administration d'agents thérapeutiques dans des cellules vivantes et des noyaux cellulaires
US9156865B2 (en) 2007-04-23 2015-10-13 Deliversir Ltd System for delivering therapeutic agents into living cells and cells nuclei
EP3032259B1 (fr) 2007-05-01 2020-04-15 Tel Hashomer Medical Research Infrastructure and Services Ltd. Procédés de détection des cellules trophoblastiques dans le sang maternel sur la base de la cytokératine-7
DK2155789T3 (da) 2007-05-01 2013-10-21 Res Dev Foundation Immunoglobulin-Fc-biblioteker
CA2688548A1 (fr) * 2007-05-02 2009-01-15 Emory University Amelioration d'incorporation de glycoproteine dans des particules de type viral
US8715674B2 (en) 2007-05-03 2014-05-06 Agency For Science, Technology And Research (A*Star) Antibodies binding to an intracellular PRL-1 or PRL-3 polypeptide
RU2468076C2 (ru) 2007-05-07 2012-11-27 Проталикс Лтд. Одноразовое устройство для культивирования и сбора растительной ткани и/или клеток, способ и система культивирования и сбора растительной ткани и/или растительных клеток
CA2686065A1 (fr) * 2007-05-10 2008-11-20 Glumetrics, Inc. Capteur de fluorescence d'equilibre de non consommation permettant de mesurer le taux de glucose intravasculaire en temps reel
US20090081639A1 (en) * 2007-05-31 2009-03-26 Phil Hill Assay for sensitivity to chemotherapeutic agents
US7776877B2 (en) 2007-06-22 2010-08-17 Chemocentryx, Inc. N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
WO2009000089A1 (fr) * 2007-06-28 2008-12-31 University Of Saskatchewan Compositions immunomodulantes et procédés de traitement d'une maladie par des peptides de défense modifiés de l'hôte
ATE540115T1 (de) 2007-07-11 2012-01-15 Yeda Res & Dev Nukleinsäurekonstruktsysteme mit fähigkeit zur diagnose oder behandlung eines zellzustands
JP5306344B2 (ja) 2007-07-12 2013-10-02 ケモセントリックス， インコーポレイテッド 炎症の治療のためのｃｃｒ２モジュレーターとしての縮合ヘテロアリールピリジルおよびフェニルベンゼンスルホンアミド
JP2010533705A (ja) 2007-07-15 2010-10-28 ヒルマン，イチャク 抗菌ペプチドまたはその阻害剤を用いた疾病治療
IL184627A0 (en) 2007-07-15 2008-12-29 Technion Res & Dev Foundation Agents for diagnosing and modulating metastasis and fibrosis as well as inflammation in a mammalian tissue
BR122020022203B1 (pt) 2007-07-24 2021-04-20 Evogene Ltd método de aumento da taxa de crescimento de uma planta
US8293685B2 (en) 2007-07-26 2012-10-23 The Regents Of The University Of California Methods for enhancing bacterial cell display of proteins and peptides
US8679485B2 (en) * 2007-08-02 2014-03-25 Gilead Biologics, Inc. Methods and compositions for treatment and diagnosis of fibrosis, tumor invasion, angiogenesis, and metastasis
AU2008284015B2 (en) 2007-08-03 2014-05-15 Musc Foundation For Research Development Human monoclonal antibodies and methods for producing the same
JP5777340B2 (ja) 2007-08-06 2015-09-09 オリオン ゲノミクス エルエルシー Ｉｇｆ２遺伝子の対立遺伝子特異的な発現を判定するための一塩基多型ならびに新規および公知の多型の組み合わせ
US7790401B2 (en) 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
WO2009032477A2 (fr) 2007-08-08 2009-03-12 The Board Of Regents Of The University Of Texas System Peptides ciblant vegfr-1/nrp-1
WO2009023676A1 (fr) 2007-08-12 2009-02-19 Integrated Dna Technologies, Inc. Système de microréseau avec spécificité de séquence améliorée
US20090136916A1 (en) * 2007-08-13 2009-05-28 Trustees Of Tufts College Methods and microarrays for detecting enteric viruses
DK2185175T3 (da) 2007-08-15 2013-05-13 Yeda Res & Dev MMP-9-regulatorer og anvendelser deraf
US8741315B2 (en) 2007-09-12 2014-06-03 Yeda Research And Development Co. Ltd. Methods of treating tumors in immune-privileged sites
EP2200622B2 (fr) 2007-09-19 2015-07-29 Pluristem Ltd. Cellules adhérentes provenant de tissus adipeux ou placentaires et leur utilisation thérapeutique
EP2511708B1 (fr) 2007-10-05 2016-09-14 Affymetrix, Inc. Analyses à base de particules hautement multiplexées
WO2009052179A2 (fr) 2007-10-15 2009-04-23 Idexx Laboratories, Inc. Lipase pancréatique féline
AU2008313274A1 (en) 2007-10-19 2009-04-23 Rappaport Family Institute For Research In The Medical Sciences Compositions comprising semaphorins for the treatment of angiogenesis related diseases and methods of selection thereof
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
US20100240070A1 (en) * 2007-11-07 2010-09-23 Beckman Coulter, Inc. Nonseparation Assay Methods Using Peroxide Generating Enzymes
WO2009067626A1 (fr) 2007-11-21 2009-05-28 Glumetrics, Inc. Utilisation d'un capteur intravasculaire à l'équilibre pour parvenir à une maîtrise précise de la glycémie
JP5264421B2 (ja) * 2007-11-22 2013-08-14 富士フイルム株式会社 被験物測定用担体およびその製造方法
EP2599790A1 (fr) 2007-11-26 2013-06-05 Yissum Research Development Company of The Hebrew University of Jerusalem Compositions comprenant des polypeptides fibreux et des polysachharides
US7910378B2 (en) 2007-12-14 2011-03-22 Siemens Healthcare Diagnostics Inc. Methods for detection of hydrophobic drugs
CA2710713C (fr) 2007-12-27 2017-09-19 Protiva Biotherapeutics, Inc. Silencage de l'expression de la polo-like kinase a l'aide d'un arn interferent
CN101977928B (zh) 2007-12-27 2014-12-10 伊沃基因有限公司 用于改进植物的水分利用效率、肥料利用效率、生物/非生物胁迫耐受性、产量和生物量的分离多肽、多核苷酸
US9605035B2 (en) 2008-01-10 2017-03-28 Research Development Foundation Vaccines and diagnostics for the ehrlichioses
MX2010008096A (es) 2008-01-25 2010-09-22 Amgen Inc Anticuerpos de ferroportina y metodos de uso.
AU2009208607B2 (en) * 2008-01-31 2013-08-01 Compugen Ltd. Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
ES2458870T3 (es) 2008-02-07 2014-05-07 Cornell University Procedimientos para prevenir o tratar la resistencia a la insulina
US20090203531A1 (en) 2008-02-12 2009-08-13 Nurith Kurn Method for Archiving and Clonal Expansion
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
WO2009104175A2 (fr) 2008-02-21 2009-08-27 Technion Research & Development Foundation Ltd. Utilisation de microtubes électrofilés pour l'administration de médicaments
US20090311695A1 (en) * 2008-03-12 2009-12-17 Talat Nasim Method
WO2009117698A2 (fr) 2008-03-21 2009-09-24 Nugen Technologies, Inc. Procédés d'amplification d'arn en présence d'adn
AU2009227935B2 (en) 2008-03-28 2015-07-09 Mdna Life Sciences Inc. Aberrant mitochondrial DNA, associated fusion transcripts and hybridization probes therefor
EP2107125A1 (fr) 2008-03-31 2009-10-07 Eppendorf Array Technologies SA (EAT) PCR en temps réel de cibles sur un micro-réseau
PL2757091T3 (pl) 2008-04-01 2017-10-31 Biosearch Tech Inc Stabilizowane ciemne wygaszające sondy fluoroforowe kwasu nukleinowego
JP2011516094A (ja) 2008-04-15 2011-05-26 プロチバ バイオセラピューティクス インコーポレイティッド 干渉ｒｎａを用いたｃｓｎ５遺伝子発現のサイレンシング方法
WO2009127060A1 (fr) 2008-04-15 2009-10-22 Protiva Biotherapeutics, Inc. Nouvelles formulations lipidiques pour l'administration d'acides nucléiques
WO2009129186A2 (fr) 2008-04-17 2009-10-22 Glumetrics, Inc. Capteur pour déploiement intra-vasculaire percutané sans canule à demeure
US9095569B2 (en) 2008-04-18 2015-08-04 Collplant Ltd. Methods of generating and using procollagen
DK2268129T3 (en) 2008-04-21 2015-09-28 Danziger Innovations Ltd PLANTEVIRUSEKSPRESSIONSVEKTORER AND USE THEREOF FOR GENERATING GENOTYPEVARIATIONER into plant genomes
EP2274592A4 (fr) * 2008-04-23 2011-09-07 Luminex Corp Méthode de création d un étalon pour plusieurs analytes présents dans une matière première d origine biologique
JP2012500620A (ja) 2008-04-24 2012-01-12 ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク Ｄｎａ分子組織化のための幾何学的パターンおよび脂質二重層、ならびにその使用
WO2009133464A2 (fr) 2008-04-30 2009-11-05 Danisco A/S Procédé d'oxydation
EP2620448A1 (fr) 2008-05-01 2013-07-31 Amgen Inc. Anticorps anti-hepcidine et méthodes d'utilisation associées
SG157299A1 (en) 2008-05-09 2009-12-29 Agency Science Tech & Res Diagnosis and treatment of kawasaki disease
WO2009140666A2 (fr) 2008-05-15 2009-11-19 Ribomed Biotechnologies, Inc. Procédés et réactifs pour détecter une méthylation de cpg avec une protéine de liaison méthyle-cpg (mbp)
MX2010012697A (es) 2008-05-22 2011-03-15 Evogene Ltd Polinucleotidos y polipeptidos aislados y metodos para usarlos para incrementar el rendimiento de plantas, biomasa, velocidad de crecimiento, vigor, contenido de aceite, tolerancia al estres abiotico de las plantas y eficiencia de uso de nitrogeno.
WO2009141687A1 (fr) * 2008-05-22 2009-11-26 Centre National De La Recherche Scientifique (Cnrs) Nouveaux composés optiquement purs pour une efficacité thérapeutique améliorée
WO2009144720A1 (fr) 2008-05-27 2009-12-03 Pluristem Ltd. Procédés de traitement de maladies inflammatoires du côlon
WO2009144718A1 (fr) 2008-05-28 2009-12-03 Ramot At Tel Aviv University Ltd. Cellules souches mésenchymateuses destinées au traitement de troubles du snc
US8791258B2 (en) * 2008-06-10 2014-07-29 The Regents Of The University Of California Pro-fluorescent probes
FI20085579A0 (fi) * 2008-06-12 2008-06-12 Valtion Teknillinen Kannabiskäytön toteaminen
EP2326419B1 (fr) 2008-06-29 2021-04-07 Realbio Technologies Ltd. Dispositif de transfert de liquide particulièrement utile comme dispositif de capture dans un processus de dosage biologique
WO2010009060A2 (fr) * 2008-07-13 2010-01-21 Ribomed Biotechnologies, Inc. Procédés par balise moléculaire pour la détection de cibles utilisant l'abscription
CN102176914B (zh) 2008-08-08 2014-12-17 新加坡科技研究局 用于诊断和治疗癌症的vhz
EP2320953B1 (fr) 2008-08-08 2015-07-15 Genisphere, LLC Dendrimères d'adn à longue durée d'action et méthodes afférentes
US20120034156A1 (en) * 2010-08-03 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Artificial cells
BR122021014165B1 (pt) 2008-08-18 2022-08-16 Evogene Ltd. Método para aumentar a eficiência de uso do nitrogênio, eficiência de uso de fertilizantes, produção, biomassa e/ou tolerância ao estresse por deficiência de nitrogênio e seca de uma planta, e, construção de ácido nucleico isolado
CA2735790C (fr) 2008-09-02 2017-02-28 Pluristem Ltd. Cellules adherentes provenant d'un tissu placentaire et leur utilisation en therapie
EP3216874A1 (fr) 2008-09-05 2017-09-13 TOMA Biosciences, Inc. Procédés pour la stratification et l'annotation des options de traitement médicamenteux contre le cancer
US8367392B2 (en) * 2008-09-05 2013-02-05 Transalgae Ltd. Genetic transformation of algal and cyanobacteria cells by microporation
US20110305682A1 (en) 2008-09-11 2011-12-15 Ben Gurion University Of The Negev Research And Development Authority Compositions and Methods for Treating S. Pneumonia Infection
RU2535966C2 (ru) 2008-09-12 2014-12-20 Криопрашис Криобиоложия Лтда. Клеточная терапия ишемической ткани
EP2344521B1 (fr) 2008-09-24 2019-08-21 Tel HaShomer Medical Research Infrastructure and Services Ltd. Peptides et compositions destinés à prévenir l'adhérence cellulaire et procédés d'utilisation de ceux-ci
WO2010036323A1 (fr) 2008-09-25 2010-04-01 University Of Massachusetts Medical School Procédé d'identification des interactions entre des loci génomiques
CA2736729A1 (fr) 2008-09-29 2010-04-01 Ben Gurion University Of The Negev Research And Development Authority Beta-peptides amyloides et procedes d'utilisation associes
DE102008049601A1 (de) 2008-09-30 2010-04-01 Siemens Healthcare Diagnostics Products Gmbh Antikörper zur Bestimmung des Prothrombin-Fragments F2/F1+2 in einem homogenen Immunoassay
MX345298B (es) * 2008-10-30 2017-01-24 Evogene Ltd Polinucleótidos y polipéptidos aislados y métodos para utilizarlos para aumentar el rendimiento de la planta, biomasa, tasa de crecimiento, vigor, contenido de aceite, tolerancia al estrés abiótico de las plantas y eficacia en el uso de nitrógeno.
EP2350131B1 (fr) 2008-11-07 2017-06-07 Research Development Foundation Compositions et méthodes pour l'inhibition de la formation et de la signalisation du complexe cripto/grp78
US20110229892A1 (en) 2008-11-17 2011-09-22 Yehuda G Assaraf Method for predicting a patient's responsiveness to anti-folate therapy
WO2010058396A1 (fr) 2008-11-19 2010-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Anticorps anti-cd44vra et procédés diagnostiques et thérapeutiques l'utilisant
WO2010061383A1 (fr) 2008-11-26 2010-06-03 Biodalia Microbiological Technologies Ltd. Procédé permettant d’enrichir in-situ des aliments avec des fructanes
WO2010064231A1 (fr) 2008-12-02 2010-06-10 Tel Hashomer Medical Research Infrastructure And Services Ltd. Procédés d’analyse d’édition d’arn a-i et constructions d’acide nucléique capables de ceux-ci
WO2010064247A1 (fr) 2008-12-03 2010-06-10 Tel Hashomer Medical Research Infrastructure And Services Ltd. Procédés et trousses pour déterminer une prédisposition au cancer
EP2370092A1 (fr) 2008-12-03 2011-10-05 Research Development Foundation Modulation de l'angiogenèse à médiation par olfml-3
US8445637B2 (en) 2008-12-05 2013-05-21 Abraxis Bioscience, Llc SPARC binding peptides and uses thereof
EP2633854B1 (fr) 2008-12-05 2015-09-16 Yeda Research And Development Co. Ltd. miRNA-9 or miRNA-9* pour l'uilisation dans le traitement de la SLA
WO2010066252A1 (fr) 2008-12-09 2010-06-17 Dako Denmark A/S Procédé d'évaluation de prétraitement
WO2010068757A1 (fr) 2008-12-12 2010-06-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions et procédés utiles pour détecter et traiter des maladies associées à des ruptures du chromosome 16p
WO2010071610A1 (fr) 2008-12-19 2010-06-24 Agency For Science, Technology And Research (A*Star) Marqueurs biologiques de chikungunya sévère
AU2009334452B2 (en) 2008-12-29 2015-06-11 Tel Hashomer Medical Research, Infrastructure And Services Ltd Peptides and compositions for prevention of cell adhesion and methods of using same
MX340023B (es) 2008-12-29 2016-06-22 Evogene Ltd Polinucleotidos, polipeptidos codificados, y metodos para utilizarlos para aumentar la tolerancia al estres abiotico, biomasa y/o rendimiento en plantas que los expresan.
EP2808402A3 (fr) 2008-12-29 2015-03-25 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Méthodes de prédiction de la réponse au traitement par interférons
US8455263B2 (en) 2008-12-30 2013-06-04 Jin Po Lee Quantitative analyte assay device and method
WO2010076794A1 (fr) 2008-12-31 2010-07-08 Technion Research & Development Foundation Ltd. Procédé pour dénitrifier une saumure et systèmes aptes à une telle dénitrification
WO2010080769A2 (fr) 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Procédés et compositions chimiothérapeutiques
IL196820A0 (en) 2009-02-01 2009-11-18 Yissum Res Dev Co Devitalized, acellular scaffold matrices derived from micro-organs seeded with various cells
CN102369015A (zh) 2009-02-02 2012-03-07 雷蒙特亚特特拉维夫大学有限公司 肽、包含该肽的药物组合物及其用途
WO2010089707A1 (fr) 2009-02-04 2010-08-12 Yeda Research And Development Co. Ltd. Procédé et trousses pour déterminer la sensibilité ou la résistance d'un cancer prostatique à une radiothérapie
PT3301446T (pt) 2009-02-11 2020-07-14 Caris Mpi Inc Perfilagem molecular de tumores
EP2396429B1 (fr) 2009-02-11 2015-05-27 Orion Genomics, LLC Combinaisons de polymorphismes destinées à déterminer l'expression spécifique des allèles d'igf2
WO2010096658A1 (fr) 2009-02-19 2010-08-26 The Cleveland Clinic Foundation Corine en tant que marqueur pour une insuffisance cardiaque
EP2401362B1 (fr) 2009-02-26 2017-04-12 Tel HaShomer Medical Research Infrastructure and Services Ltd. Populations isolées de cellules souches rénales et leurs procédés d'isolement et d'utilisation
EP2403956B1 (fr) 2009-03-02 2015-11-25 Evogene Ltd. Polynucléotides et polypeptides isolés, et procédés d'utilisation de ceux-ci pour augmenter un rendement végétal et/ou des caractéristiques agricoles
CN103604786B (zh) 2009-03-03 2017-01-11 万迈医疗仪器有限公司 用于高灵敏度荧光分析的检测系统和方法
PL2406279T3 (pl) 2009-03-09 2016-07-29 Univ Ramot Kompozycje do zapobiegania i leczenia chorób neurodegeneratywnych.
US9347947B2 (en) 2009-03-12 2016-05-24 Siemens Healthcare Diagnostics Inc. Immunoassays employing non-particulate chemiluminescent reagent
WO2010103517A1 (fr) 2009-03-12 2010-09-16 Rappaport Family Institute For Research In The Medical Sciences Compositions solubles pour le traitement de maladies associées aux ligands cxcr3
CN102421914A (zh) 2009-03-15 2012-04-18 里伯米德生物技术公司 基于流产转录的分子检测
US20100240065A1 (en) * 2009-03-18 2010-09-23 Boehringer Ingelheim International Gmbh Prolyl Hydroxylase Compositions and Methods of Use Thereof
US8481698B2 (en) * 2009-03-19 2013-07-09 The President And Fellows Of Harvard College Parallel proximity ligation event analysis
US10196700B2 (en) 2009-03-24 2019-02-05 University Of Chicago Multivolume devices, kits and related methods for quantification and detection of nucleic acids and other analytes
US9464319B2 (en) 2009-03-24 2016-10-11 California Institute Of Technology Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes
CN104722342B (zh) 2009-03-24 2017-01-11 芝加哥大学 滑动式芯片装置和方法
US9447461B2 (en) 2009-03-24 2016-09-20 California Institute Of Technology Analysis devices, kits, and related methods for digital quantification of nucleic acids and other analytes
US20100291100A1 (en) * 2009-03-27 2010-11-18 Gojo Industries, Inc. Compositions And Methods For Screening And Using Compounds Antagonizing Spore-Surface Interactions
RU2011137486A (ru) 2009-03-27 2013-05-10 Митомикс Инк. Аберрантная митохондриальная днк, ассоциированные с ней слитые транскрипты, продукты трансляции и гибрадизационные зонды
US20120020954A1 (en) 2009-03-30 2012-01-26 Anat Achiron Methods of predicting clinical course and treating multiple sclerosis
CA2759201A1 (fr) 2009-04-01 2010-10-07 The Medical Research, Infrastructure, And Health Services Fund Of The Te L Aviv Medical Center Procede de regulation de la proliferation et de la differenciation des keratinocytes
WO2010116375A1 (fr) 2009-04-08 2010-10-14 Yeda Research And Development Co. Ltd. Peptides isolés pour réguler l'apoptose
SG175282A1 (en) 2009-04-21 2011-11-28 Genetic Technologies Ltd Methods for obtaining fetal genetic material
GB0908770D0 (en) 2009-04-24 2009-07-01 Danisco Method
ES2668874T3 (es) 2009-04-30 2018-05-22 Tel Hashomer Medical Research Infrastructure And Services Ltd. Anticuerpos anti-CEACAM1 y métodos de uso de los mismos
WO2010124689A1 (fr) 2009-05-01 2010-11-04 Dako Denmark A/S Nouveau cocktail d'anticorps
CN102460174B (zh) * 2009-05-14 2016-03-16 牛津大学之校长及学者 使用一组新型低丰度人类血浆蛋白生物标记对肝纤维化进行临床诊断
BRPI1011036A8 (pt) 2009-05-19 2017-11-07 Danisco Uso
US9182403B2 (en) 2009-05-19 2015-11-10 Zetiq Technologies Ltd. Kits for and methods of differential staining of cervical cancer cells and/or tissues
EP2432499A2 (fr) 2009-05-20 2012-03-28 Schering Corporation Modulation de récepteurs pilr pour traiter les infections microbiennes
WO2010137013A1 (fr) 2009-05-27 2010-12-02 Ramot At Tel Aviv University Ltd. Unités cristallisées de photosystème i dérivées du pois et leur utilisation dans des dispositifs solides
WO2010137021A2 (fr) 2009-05-27 2010-12-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédé de génération de tissu conjonctif
EP2435072A2 (fr) 2009-05-27 2012-04-04 Yeda Research and Development Co. Ltd. Inhibiteurs des protéasomes et leurs utilisations
US20120070449A1 (en) 2009-05-28 2012-03-22 Yeda Research And Development Co. Ltd. Methods of treating inflammation
AU2010256880B2 (en) 2009-06-02 2015-01-22 Opko Health, Inc. Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases
US9096865B2 (en) 2009-06-10 2015-08-04 Evogene Ltd. Isolated polynucleotides and polypeptides, and methods of using same for increasing nitrogen use efficiency, yield, growth rate, vigor, biomass, oil content, and/or abiotic stress tolerance
AU2010264072A1 (en) 2009-06-24 2012-02-16 Health Corporation - Rambam Methods and kits for isolating placental derived microparticles and use of same for diagnosis of fetal disorders
JP2012531197A (ja) 2009-06-25 2012-12-10 デュポン ニュートリション バイオサイエンシーズ エーピーエス タンパク質
ES2613498T3 (es) 2009-07-01 2017-05-24 Protiva Biotherapeutics Inc. Nuevas formulaciones de lípidos para el suministro de agentes terapéuticos a tumores sólidos
US12203113B2 (en) 2009-07-09 2025-01-21 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US9663778B2 (en) 2009-07-09 2017-05-30 OPKO Biologies Ltd. Long-acting coagulation factors and methods of producing same
WO2011004379A1 (fr) 2009-07-10 2011-01-13 Tel Hashomer Medical Research Infrastructure And Services Ltd. Compositions et méthodes de traitement du cancer
DK2907873T3 (en) 2009-07-17 2016-06-13 Bioatla Llc Simultaneously integrated selection and development of antibody / protein performance and their expression in production hosts
WO2011011447A1 (fr) 2009-07-20 2011-01-27 Protiva Biotherapeutics, Inc. Compositions et méthodes pour rendre silencieuse l’expression du gène du virus ebola
CA2768725A1 (fr) 2009-07-21 2011-01-27 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methode de diagnostic du cancer
GB0913442D0 (en) 2009-07-31 2009-09-16 Univ Ramot Cell-targeting nanoparticles comprising polynucleotide agents and uses thereof
EP2462164A2 (fr) 2009-08-04 2012-06-13 Biosystems International SAS Biomarqueurs du cancer du poumon
US20120148546A1 (en) 2009-08-17 2012-06-14 Technion Research & Development Foundation Ltd. Pericyte progenitor cells and methods of generating and using same
WO2011021171A1 (fr) 2009-08-21 2011-02-24 Beeologics, Llc Prévention et traitement de maladies des insectes bénéfiques par l’intermédiaire de molécules transcrites végétales
EP2467396A4 (fr) 2009-08-21 2012-12-26 Gilead Biologics Inc Domaines catalytiques provenant de la lysyle oxydase et de loxl2
WO2011025790A1 (fr) 2009-08-24 2011-03-03 Lumiphore, Inc. Chélateurs hopo macrocycliques
WO2011024172A2 (fr) 2009-08-27 2011-03-03 Technion Research & Development Foundation Ltd. Compositions liposomales et leurs utilisations
CN103951753B (zh) 2009-09-03 2018-01-12 默沙东公司 抗‑gitr抗体
WO2011027966A2 (fr) 2009-09-03 2011-03-10 Seegene, Inc. Sonde td et ses utilisations
WO2011030336A1 (fr) 2009-09-08 2011-03-17 Ramot At Tel-Aviv University Ltd. Procédés de diagnostic de la sclérose latérale amyotrophique (sla)
EP2475381A2 (fr) 2009-09-08 2012-07-18 Yeda Research and Development Co. Ltd. Procédés pour la mobilisation de précurseur hématopoïétique
US20120171213A1 (en) 2009-09-10 2012-07-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of treating tumors
US20120244185A1 (en) 2009-09-16 2012-09-27 Vaxart ,Inc. Immunization strategy to prevent h1n1 infection
EP2478009B1 (fr) 2009-09-17 2016-06-01 Ramot at Tel-Aviv University Ltd. Peptides pour le traitement de troubles liés au stress oxydatif
US8735124B2 (en) 2009-09-17 2014-05-27 Yeda Research And Development Co. Ltd. Isolated PON1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
EP2478093A2 (fr) 2009-09-17 2012-07-25 Yeda Research and Development Co. Ltd. Polypeptides pon1 isolés, polynucléotides codant pour ceux-ci et utilisations de ceux-ci dans le traitement ou la prévention des dommages associés à l'exposition à un organophosphate
WO2011038160A2 (fr) 2009-09-23 2011-03-31 Protiva Biotherapeutics, Inc. Compositions et procédés pour réduire au silence des gènes exprimés dans le cancer
WO2011038403A1 (fr) 2009-09-28 2011-03-31 Yuling Luo Procédés de détection de séquences d'acide nucléique à spécificité élevée
WO2011041546A1 (fr) 2009-09-30 2011-04-07 Glumetrics, Inc. Capteurs dotés de revêtements thromborésistants
US20110081706A1 (en) * 2009-10-02 2011-04-07 TransAlgae Ltd Method and system for efficient harvesting of microalgae and cyanobacteria
WO2011044186A1 (fr) 2009-10-06 2011-04-14 The Board Of Trustees Of The University Of Illinois Récepteurs de lymphocytes t à chaîne unique humains
ES2666372T3 (es) 2009-10-11 2018-05-04 Biogen Ma Inc. Ensayos relacionados con anti-VLA-4
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
CN102906263B (zh) 2009-10-14 2017-05-31 耶路撒冷希伯来大学伊森姆研究发展公司 用于控制蜂中的瓦螨的组合物
CA2777663A1 (fr) 2009-10-16 2011-04-21 University Of Medicine And Dentistry Of New Jersey Procede de traitement d'une lesion chronique du tissu nerveux a l'aide d'une strategie de therapie de cellules
WO2011048600A1 (fr) 2009-10-21 2011-04-28 Danziger Innovations Ltd. Génération de variations génotypiques dans des génomes de plantes par infection d'un gamète
EP2494077A4 (fr) 2009-10-27 2013-08-21 Caris Mpi Inc Profilage moléculaire pour médecine personnalisée
US8467843B2 (en) 2009-11-04 2013-06-18 Glumetrics, Inc. Optical sensor configuration for ratiometric correction of blood glucose measurement
KR20110050327A (ko) 2009-11-07 2011-05-13 주식회사 씨젠 Ｔｈｄ 프라이머 타겟 검출
IL201999A (en) 2009-11-08 2017-10-31 Medical Res & Development Fund For Health Services Bnai Zion Medical Center The State Of Israel A knockout mouse of the 1 – mo gene, a gene associated with morbidly extreme obesity
WO2011058555A1 (fr) 2009-11-12 2011-05-19 Yeda Research And Development Co. Ltd. Procédé d'édition de l'adn dans une cellule et constructions ayant cette capacité
WO2011058557A1 (fr) 2009-11-12 2011-05-19 Ramot At Tel-Aviv University Ltd. Compositions contenant du pedf et leurs utilisations dans le traitement et la prévention de syndromes liés aux ovaires
EP2499236B1 (fr) 2009-11-12 2020-01-01 Technion Research & Development Foundation Ltd. Milieu de culture, cultures de cellules et procédés de culture de cellules souches pluripotentes dans un état indifférencié
CN108707584A (zh) 2009-11-17 2018-10-26 Musc研究发展基金会 针对人核仁素的人单克隆抗体
US20120230974A1 (en) 2009-11-17 2012-09-13 Protalix Ltd Alkaline alpha galactosidase for the treatment of fabry disease
US8592151B2 (en) * 2009-11-17 2013-11-26 Musc Foundation For Research Development Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids
GB0920089D0 (en) 2009-11-17 2009-12-30 Danisco Method
US9733242B2 (en) 2012-10-07 2017-08-15 Sevident, Inc. Devices for capturing analyte
US9910040B2 (en) 2012-07-09 2018-03-06 Sevident, Inc. Molecular nets comprising capture agents and linking agents
WO2011064773A1 (fr) 2009-11-24 2011-06-03 Collplant Ltd. Procédé de production de fibres de collagène
AU2010322808B9 (en) 2009-11-30 2014-08-07 Pluri Biotech Ltd Adherent cells from placenta and use of same in disease treatment
US8652788B2 (en) * 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
US8835120B2 (en) * 2009-12-02 2014-09-16 Abbott Laboratories Assay for cardiac troponin-T (cTnT)
US20110136141A1 (en) 2009-12-03 2011-06-09 Abbott Laboratories Peptide reagents and method for inhibiting autoantibody antigen binding
US8183002B2 (en) 2009-12-03 2012-05-22 Abbott Laboratories Autoantibody enhanced immunoassays and kits
WO2011067745A2 (fr) 2009-12-06 2011-06-09 Rosetta Green Ltd. Compositions et procédés d'amélioration de résistance de plantes au stress abiotique
WO2011072091A1 (fr) 2009-12-09 2011-06-16 Quark Pharmaceuticals, Inc. Méthodes et compositions utilisées pour le traitement de maladies, d'affections ou de lésions du snc
EP2513308B1 (fr) 2009-12-17 2017-01-18 Merck Sharp & Dohme Corp. Modulation de pilr pour le traitement de troubles immunitaires
EP2516679B1 (fr) 2009-12-21 2017-08-23 Seegene, Inc. Détection de cible par amorce tsg
WO2011087707A1 (fr) 2009-12-22 2011-07-21 Elitech Holding B.V. Sonde de substrat de l'endonucléase iv hyperthermostable
GB0922377D0 (en) 2009-12-22 2010-02-03 Arab Gulf University The Mutant LDL receptor
EP2519097B1 (fr) 2009-12-28 2016-03-02 Evogene Ltd. Polynucléotides isolés et polypeptides et procédés pour les utiliser afin d'augmenter le rendement des cultures, la biomasse, la vitesse de croissance, la vigueur, la teneur en huile, la tolérance au stress abiotique des plantes et l'efficacité d'utilisation de l'azote
AU2010337829B2 (en) 2009-12-29 2015-03-19 Gamida-Cell Ltd. Methods for enhancing natural killer cell proliferation and activity
SG182367A1 (en) 2010-01-05 2012-08-30 Vascular Biogenics Ltd Methods for use of a specific anti-angiogenic adenoviral agent
EP4152004B9 (fr) 2010-01-11 2025-04-09 Biogen MA Inc. Essai d'anticorps anti-virus jc
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
EP2523681A1 (fr) 2010-01-12 2012-11-21 Vascular Biogenics Ltd. Procédés de production de vecteurs adénoviraux et préparations virales générées par ce biais
WO2011092700A1 (fr) 2010-01-27 2011-08-04 Yeda Research And Development Co. Ltd. Anticorps inhibant les métalloprotéines
ES2719502T3 (es) 2010-01-29 2019-07-10 Advanced Cell Diagnostics Inc Métodos de detección in situ de ácidos nucleicos
KR101851117B1 (ko) 2010-01-29 2018-04-23 마이크로닉스 인코포레이티드. 샘플-투-앤서 마이크로유체 카트리지
US8574832B2 (en) * 2010-02-03 2013-11-05 Massachusetts Institute Of Technology Methods for preparing sequencing libraries
CN105622757A (zh) 2010-02-04 2016-06-01 吉联亚生物科技有限公司 结合赖氨酰氧化酶样2（loxl2）的抗体和其使用方法
US8609092B2 (en) 2010-02-08 2013-12-17 Agensys, Inc. Antibody drug conjugates (ADC) that bind to 161P2F10B proteins
US9410131B2 (en) 2010-02-11 2016-08-09 Yeda Research And Development Co. Ltd. Enzymatic systems for carbon fixation and methods of generating same
EP2538961B1 (fr) 2010-02-24 2016-10-12 Ben Gurion University Of The Negev Research And Development Authority Inhibition de la nécrose
WO2011107939A1 (fr) 2010-03-01 2011-09-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Méthodes de prédiction de l'efficacité d'un traitement par anti-vegfa pour des tumeurs solides
WO2011107994A1 (fr) 2010-03-04 2011-09-09 Yeda Research And Development Co. Ltd. Procédés de mesure de la stabilité d'une protéine
WO2011111034A1 (fr) 2010-03-08 2011-09-15 Yeda Research And Development Co. Ltd. Production de protéines recombinantes dans des systèmes hétérologues
BR112012022570A2 (pt) 2010-03-08 2015-10-06 Monsato Technology Llc moléculas de polinucleotídeo para regulação de gene em plantas.
US20120329089A1 (en) 2010-03-11 2012-12-27 Jacob Edrei Methods of generating hydrogen
WO2011114251A1 (fr) 2010-03-18 2011-09-22 Danisco A/S Produits alimentaires
WO2011125015A2 (fr) 2010-04-05 2011-10-13 Bar-Ilan University Polypeptides formant des pores pouvant être activés par une protéase
KR20130048217A (ko) 2010-04-06 2013-05-09 메사추세츠 인스티튜트 오브 테크놀로지 적은 수의 전사체 측정치를 이용한 유전자 발현 프로파일링
US9125931B2 (en) 2010-04-06 2015-09-08 Massachusetts Institute Of Technology Post-transcriptional regulation of RNA-related processes using encoded protein-binding RNA aptamers
WO2011128897A1 (fr) 2010-04-12 2011-10-20 Technion Research & Development Foundation Ltd. Population de cellules progénitrices pancréatiques et leurs méthodes d'isolement et d'utilisation
EP2557913B1 (fr) 2010-04-12 2016-08-03 Ben Gurion University Of The Negev Research And Development Authority Sulfotransférase d'une microalgue rouge et utilisations de celle-ci
JP5786020B2 (ja) 2010-04-16 2015-09-30 アボットジャパン株式会社 関節リウマチを診断する方法および試薬
CN103109185A (zh) 2010-04-18 2013-05-15 耶达研究及发展有限公司 用于治疗ErbB/ErbB配体相关疾病的分子和使用所述分子的方法
BR112012027504B1 (pt) 2010-04-28 2022-05-24 Evogene Ltd Método de aumento de produção, biomassa, taxa de crescimento, e/ou tolerância ao estresse abiótico de uma planta, e, construção de ácidos nucleicos
WO2011138778A2 (fr) 2010-05-04 2011-11-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédés permettant d'identifier des inhibiteurs de polypeptides d'intérêt
US9352000B2 (en) 2010-05-05 2016-05-31 Rappaport Family Institute For Research In The Medical Sciences Use of CCL1 in therapy
IL208820A0 (en) 2010-10-19 2011-01-31 Rachel Teitelbaum Biologic female contraceptives
US20120190563A1 (en) 2010-05-07 2012-07-26 Abbott Laboratories Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
MX2012012986A (es) 2010-05-07 2013-03-05 Abbvie Inc Metodos para predecir la sensibilidad al tratamiento con un inhibidor de cinasa de tirosina dirigido.
ES2672918T3 (es) 2010-05-13 2018-06-18 Tel Hashomer Medical Research Infrastructure And Services Ltd. Poblaciones aisladas de células renales adultas y métodos para aislar y usar las mismas
EP2572197A4 (fr) 2010-05-18 2013-08-28 Texas A & M Univ Sys Procédé et composition pour le diagnostic et le suivi de maladies inflammatoires
US9624285B2 (en) 2010-06-03 2017-04-18 Ramot a Tel-Aviv University Ltd. Methods of treating diabetes and compositions capable of same
CN102933723A (zh) 2010-06-07 2013-02-13 奥斯娜特·阿舒尔-费边 用于诊断与缺氧有关的病状的方法和试剂盒
EP2395354A1 (fr) 2010-06-10 2011-12-14 Siemens Healthcare Diagnostics Products GmbH Test d'activité homogène destiné à la détermination de réactions enzymatiques
US9187787B2 (en) 2010-06-16 2015-11-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of diagnosing and treating cancer
BR112012032126A2 (pt) 2010-06-16 2017-10-17 Futuragene Israel Ltd Empresa Isralense polinucleotídeo isolado, estrutura de ácido nucléico, sistema de estrutura de ácido nucléico, polipeptídeo isolado, planta, composição inseticida, e método para controlar ou exterminar um inseto
US8329424B2 (en) 2010-06-25 2012-12-11 Siemens Healthcare Diagnostics Reduction in false results in assay measurements
US20130316338A1 (en) 2010-06-29 2013-11-28 The United States Government As Represented By The Department Of Veterans Affairs CCR6 As A Biomarker of Alzheimer's Disease
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
ES2817780T3 (es) 2010-07-12 2021-04-08 The State Of Israel Ministry Of Agriculture And Rural Development Agricultural Res Organization A R Polinucleótidos aislados y métodos y plantas que usan los mismos para regular la acidez de las plantas
EP2407242A1 (fr) 2010-07-13 2012-01-18 Dublin City University Analyse de clone directe et technologie de sélection
BR112013000984A2 (pt) 2010-07-15 2017-10-03 Technion Res & Dev Foundation Estrutura de ácido nucleico para o aumento da tolerância ao estresse abiótico em plantas
BR112013000985A2 (pt) 2010-07-15 2017-09-05 Technion Res & Dev Foundation Entidades isoladas de alta afinidade com especificidade semelhante à do receptor de célula t em relação a complexos nativos de mhc classe ii e peptídeos autoantigênicos de descarboxilase do ácido glutâmico (gad)
WO2012007950A2 (fr) 2010-07-15 2012-01-19 Technion Research & Development Foundation Ltd. Entités de haute affinité isolées présentant une spécificité de type récepteur des lymphocytes t pour les complexes natifs du mhc de classe ii et les peptides auto-antigéniques associés au diabète
CA2804746C (fr) 2010-07-16 2022-01-11 Jay M. Short Nouveaux procedes d'evolution proteique
CN103153467A (zh) 2010-07-16 2013-06-12 范德比尔特大学 用于提取、浓缩和检测分子物类的使用表面张力阀的低资源处理器
EP2595637B1 (fr) 2010-07-22 2017-11-01 Cellect Biotherapeutics Ltd. Cellules immunitaires régulatrices possédant un effet de destruction cellulaire ciblé accru
WO2012012748A2 (fr) 2010-07-23 2012-01-26 Luminex Corporation Co-couplage pour réguler la réactivité des réactifs dans des dosages immunologiques
US9120862B2 (en) 2010-07-26 2015-09-01 Abbott Laboratories Antibodies relating to PIVKA-II and uses thereof
US9144585B2 (en) 2010-07-27 2015-09-29 Technion Research & Development Foundation Limited Isolated mesenchymal progenitor cells and extracellular matrix produced thereby
US20130130311A1 (en) 2010-07-27 2013-05-23 Yeda Research And Development Co., Ltd. Methods and systems for assessing clonality of cell cultures
JP2013535966A (ja) 2010-07-27 2013-09-19 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド 引き抜かれた毛包由来のケラチン生成細胞から誘導多能性幹細胞を生成させる方法
AU2011285694B2 (en) 2010-08-04 2014-12-18 Idexx Laboratories, Inc. Detection of degradation products of canine NT-proBNP
US8901074B2 (en) 2010-08-04 2014-12-02 Ramot At Tel-Aviv University Methods of treating autoimmune diseases of the central nervous system (CNS) and neurodegenerative diseases
US10088490B2 (en) 2010-08-20 2018-10-02 Siemens Healthcare Diagnostics Inc. Assay for analytes using multiple receptors
EP2606122A1 (fr) 2010-08-22 2013-06-26 Ramot at Tel Aviv University, Ltd. Cellules souches pluripotentes induites dérivées de cellules bêta pancréatiques humaines
WO2012025925A1 (fr) 2010-08-24 2012-03-01 Rappaport Family Institute For Research In The Medical Sciences Procédés d'amélioration de la transplantation en utilisant des sdf-1alpha
AU2011298034B2 (en) 2010-08-30 2016-05-26 Evogene Ltd. Isolated polynucleotides and polypeptides, and methods of using same for increasing nitrogen use efficiency, yield, growth rate, vigor, biomass, oil content, and/or abiotic stress tolerance
US10214722B2 (en) 2010-09-07 2019-02-26 Technion Research & Development Foundation Limited Methods for expanding and maintaining human pluripotent stem cells (PSCs) in an undifferentiated state in a single cell suspension culture
WO2012032519A2 (fr) 2010-09-07 2012-03-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Méthodes de diagnostic de la maladie de parkinson
EP2613799A1 (fr) 2010-09-07 2013-07-17 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Translecture d'acétylcholinestérase (ache-r) pour le traitement ou la prévention de la maladie de parkinson
WO2012032510A1 (fr) 2010-09-07 2012-03-15 Yeda Research And Development Co. Ltd. Amorces pour l'amplification d'adn et procédés de sélection de ces dernières
ES2589678T3 (es) 2010-09-08 2016-11-15 Yeda Research And Development Co. Ltd. Uso de linfocitos T de memoria central anti-terceros para el tratamiento anti-leucemia/linfoma
EP2614083A2 (fr) 2010-09-08 2013-07-17 Yeda Research and Development Co. Ltd Combinaison de médicaments immunosuppresseurs pour une prise de greffe à long terme et stable
CN103210082A (zh) 2010-09-15 2013-07-17 雷蒙特亚特特拉维夫大学有限公司 扩增胰岛β细胞和使其再分化的方法
US20130210901A1 (en) 2010-09-20 2013-08-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of treating neurodegenerative diseases
EP2619321B1 (fr) 2010-09-20 2018-08-01 Advanced Cell Diagnostics, Inc. Marqueurs biologiques permettant de différencier un mélanome d'un nævus bénin sur la peau
KR20130113447A (ko) 2010-09-24 2013-10-15 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 고정된 프라이머들을 이용하여 표적 dna의 직접적인 캡쳐, 증폭 및 서열화
PL3409287T3 (pl) 2010-09-29 2021-09-27 Agensys, Inc. Koniugaty leków i przeciwciał (adc), które wiążą białka 191p4d12
WO2012045751A2 (fr) 2010-10-04 2012-04-12 Centre National De La Recherche Scientifique (Cnrs) Composés synthétiques polyvalents en tant que traitement antibiotique
EP2441520A1 (fr) 2010-10-12 2012-04-18 Eppendorf AG Application en temps réel et détection basée sur un micro-réseau de cibles d'acides nucléiques dans un dosage sur puce de flux
US8951983B2 (en) 2010-10-17 2015-02-10 Yeda Research And Development Co. Ltd. Methods and compositions for the treatment of insulin-associated medical conditions
WO2012052878A1 (fr) 2010-10-19 2012-04-26 Vascular Biogenics Ltd. Polynucléotides isolés et constructions d'acide nucléique pour diriger l'expression d'un gène d'intérêt dans des cellules
CN104849472A (zh) 2010-10-21 2015-08-19 领先细胞医疗诊断有限公司 用于原位检测核酸的超灵敏方法
KR20120042100A (ko) 2010-10-22 2012-05-03 주식회사 씨젠 이중표지 고정화 프로브를 이용한 고상에서의 타겟 핵산서열 검출
WO2012056452A2 (fr) 2010-10-27 2012-05-03 Nanocyte (Israel) Ltd. Compositions pharmaceutiques et dispositifs d'administration comprenant des cellules ou capsules urticantes
CN103370337B (zh) 2010-10-28 2015-12-09 耶达研究及发展有限公司 用于产生针对金属酶的抗体的方法
US20130227724A1 (en) 2010-11-03 2013-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Transgenic plants with improved saccharification yields and methods of generating same
EP2635105B1 (fr) 2010-11-04 2017-12-20 Ben-Gurion University of The Negev Research and Development Authority Acyl-coa: gène de type diacylglycérol acyltransférase 1 (ptdgat1) et utilisations de celui-ci
RU2013126706A (ru) 2010-11-15 2014-12-27 Рамот Ат Тель-Авив Юниверсити Лтд. Дипептидные аналоги для лечения состояний, ассоциированных с образованием амилоидных фибрилл
EP2640404B1 (fr) 2010-11-17 2017-02-22 Ben Gurion University of The Negev Research and Development Authority Thérapie à base de cellules t pour les maladies neurodégénératives
US9574171B2 (en) 2010-12-02 2017-02-21 Technion Research & Development Foundation Ltd. Methods of generating corneal cells and cell populations comprising same
US20120183960A1 (en) 2010-12-07 2012-07-19 Enterologics, Inc. Method for identifying e. coli m-17
CA2816495C (fr) 2010-12-15 2020-10-13 Kadimastem Ltd. Cellules produisant de l'insuline derivees de cellules souches pluripotentes
US9551006B2 (en) 2010-12-22 2017-01-24 Evogene Ltd. Isolated polynucleotides and polypeptides, and methods of using same for improving plant properties
AR084358A1 (es) 2010-12-27 2013-05-08 Lilly Co Eli Composiciones y metodos para identificar y diferenciar componentes virales de vacunas multivalentes de la “fiebre de embarque” (complejo de enfermedad respiratoria bovina (brdc))
RU2013135305A (ru) 2010-12-28 2015-02-10 Камедис Лтд. Растительные экстракты для лечения и профилактики инфекций
EP2471945A1 (fr) 2010-12-30 2012-07-04 Siemens Healthcare Diagnostics Products GmbH Procédé de détermination d'inhibiteurs de coagulation
AU2011352207B2 (en) 2010-12-31 2016-03-03 Bioatla, Llc Comprehensive monoclonal antibody generation
MX340258B (es) 2011-01-11 2016-07-01 Seegene Inc Detección de secuencias de ácido nucleico objetivo mediante ensayo de escisión y extensión del pto.
WO2012099896A2 (fr) 2011-01-17 2012-07-26 Life Technologies Corporation Workflow pour la détection de ligands à l'aide d'acides nucléiques
JP5913372B2 (ja) 2011-01-20 2016-04-27 プロタリクス リミテッド 植物および植物細胞におけるα−ガラクトシダーゼの発現のための核酸発現構築物
CN103476948A (zh) 2011-01-28 2013-12-25 领先细胞医疗诊断有限公司 用于测定头颈癌和宫颈病变中的hpv状态的rnascope* hpv测定法
US20130316358A1 (en) 2011-01-31 2013-11-28 Yeda Research And Development Co. Ltd. Methods of diagnosing disease using overlap extension pcr
WO2012109133A1 (fr) 2011-02-07 2012-08-16 Research Development Foundation Polypeptides fc modifiés d'immunoglobuline
WO2012116073A2 (fr) 2011-02-23 2012-08-30 The Board Of Trustees Of The University Of Illinois Dendron-hélices amphiphiles, micelles de ceux-ci et utilisations
US20130330349A1 (en) 2011-02-23 2013-12-12 Rappaport Family Institute For Research In The Medical Sciences High affinity molecules capable of binding a type a plexin receptor and uses of same
BR112013022331B1 (pt) 2011-03-02 2021-01-26 Futuragene Israel Ltd. vetor de expressão de ácido nucleico, e, método para gerar uma planta que compreende resistência intensificada a um patógeno bacteriano
WO2012117373A1 (fr) 2011-03-03 2012-09-07 Ramot At Tel-Aviv University Ltd. Cellules musculaires génétiquement modifiées qui expriment des facteurs neurotrophiques
EA032513B1 (ru) 2011-03-06 2019-06-28 Мерк Сероно С.А. Клеточные линии с низким содержанием фукозы и их применение
WO2012120518A1 (fr) 2011-03-08 2012-09-13 Ramot At Tel-Aviv University Ltd. Compositions et méthodes de diagnostic et de traitement de phénylcétonurie (pcu)
CA2829300A1 (fr) 2011-03-08 2012-09-13 King Abdullah University Of Science And Technology Biomarqueur moleculaire destine a la detection precoce du cancer des ovaires
AU2012229156A1 (en) 2011-03-11 2013-10-31 Board Of Regents Of The University Of Nebraska Biomarker for coronary artery disease
WO2012123938A1 (fr) 2011-03-17 2012-09-20 Tel Hashomer Medical Research Infrastructure And Services Ltd. Analogues de quinolone pour le traitement de maladies auto-immunes
JP2014510084A (ja) 2011-03-17 2014-04-24 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド 二重特異性および単一特異性の非対称な抗体ならびにそれらの作製方法
KR101835917B1 (ko) 2011-03-22 2018-03-07 플루리스템 리미티드 방사선 또는 화학적 손상을 치료하는 방법들
US8969003B2 (en) 2011-03-23 2015-03-03 Elitech Holding B.V. Functionalized 3-alkynyl pyrazolopyrimidine analogues as universal bases and methods of use
WO2012129547A1 (fr) 2011-03-23 2012-09-27 Elitech Holding B.V. Analogues de 3-alcynyl pyrazolopyrimidines fonctionnalisées comme bases universelles et procédés d'utilisation
EP2688582B1 (fr) 2011-03-24 2017-02-15 Neurim Pharmaceuticals (1991) Limited Peptides neuroprotecteurs
WO2012131680A2 (fr) 2011-03-28 2012-10-04 Yeda Research And Development Co. Ltd. Compositions et procédés pour le traitement de l'inflammation
CN103476949A (zh) 2011-03-28 2013-12-25 诺瓦提斯公司 与细胞周期蛋白依赖性激酶抑制剂相关的标志物
CN103534358B (zh) 2011-03-29 2015-03-25 Seegene株式会社 基于pto切割以及延伸-依赖性切割的靶核酸序列的检测
CA3182262A1 (fr) 2011-04-01 2012-10-04 Immunogen, Inc. Procede pour augmenter l'efficacite d'une cancerotherapie ciblant folr1
DK2694095T3 (en) 2011-04-05 2018-05-28 Longevity Biotech Inc COMPOSITIONS COMPREHENSIVE GLUCAGON ANALOGS AND METHODS FOR PREPARING AND USING THE SAME
WO2012137202A1 (fr) 2011-04-05 2012-10-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Composition comprenant un indicateur de fer attaché à une microparticule et utilisations de celle-ci pour quantifier du fer non lié à la transferrine (ntbi) et du fer labile cellulaire (lci)
DK2694962T3 (en) 2011-04-06 2017-06-12 Ramot At Tel-Aviv Univ Ltd PROCEDURES FOR MONITORING AND ANALYSIS OF METABOLIC ACTIVITY PROFILES AND DIAGNOSTIC AND THERAPEUTICAL APPLICATIONS THEREOF
RU2013149861A (ru) 2011-04-08 2015-05-20 ДАНИСКО ЮЭс, ИНК. Композиции
WO2012142164A1 (fr) 2011-04-12 2012-10-18 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Anticorps monoclonaux humains qui se lient aux facteurs de croissance insulinomimétique (igf) de type i et ii
AU2012241521B2 (en) 2011-04-15 2016-07-14 Pluri Biotech Ltd Methods and systems for harvesting cells
EP2699906B1 (fr) 2011-04-20 2017-11-29 Access Medical Systems, Ltd. Amplification cyclique de polymère luminescent
MX354195B (es) 2011-05-03 2018-02-16 Evogene Ltd Polipeptidos y polinucleotidos aislados y metodos para su uso, para aumentar el rendimiento, la biomasa, el indice de crecimiento, el vigor, el contenido de aceite, la tolerancia al estrés abiotico de las plantas y la eficiencia en el uso de nitrogeno.
WO2012150749A1 (fr) 2011-05-04 2012-11-08 Seegene, Inc. Détection de séquences d'acide nucléique cibles par clivage et hybridation de po
US9192670B2 (en) 2011-05-04 2015-11-24 Ramot At Tel-Aviv University Ltd. Regulation of amyloid beta molecular composition for the treatment of alzheimer's disease
WO2012153333A1 (fr) 2011-05-09 2012-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Régénération et réparation de tissu mésenchymateux par utilisation d'amélogénine
CN103635594B (zh) 2011-05-09 2018-02-13 富鲁达公司 基于探针的核酸检测
WO2012153336A2 (fr) 2011-05-12 2012-11-15 Rakuto Bio Technologies Ltd. Procédés et dispositifs pour éclaircir la carnation de la peau
WO2012156976A1 (fr) 2011-05-16 2012-11-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédés de préparation d'artémisinine dans des plantes non-hôtes et vecteurs destinés à une utilisation dans celles-ci
WO2012161288A1 (fr) 2011-05-20 2012-11-29 Abbott Japan Co. Ltd. Procédés et réactifs d'immunodosage pour la diminution d'une liaison non spécifique
US9506051B2 (en) 2011-05-20 2016-11-29 Oligomerix, Inc. Tau protease compositions and methods of use
WO2012160526A2 (fr) 2011-05-23 2012-11-29 Ofir Menashe Formulations à base de particules contenant des micro-organismes et leurs utilisations
CA2836503C (fr) 2011-05-23 2020-09-22 Yeda Research And Development Co. Ltd. Utilisation de la phosphorylation d'akt en tant que biomarqueur pour le pronostic et le traitement de maladies neurodegeneratives
DK2801626T3 (en) 2011-05-24 2016-06-20 Elitechgroup B V Detection of methicillin-resistant Staphylococcus aureus.
EP2715353B1 (fr) 2011-05-31 2016-08-24 IDEXX Laboratories, Inc. Détection des produits de dégradation de la nt-probnp féline
SG195190A1 (en) 2011-05-31 2013-12-30 Hutchison Biofilm Medical Solutions Ltd Dispersion and detachment of cell aggregates
LT3575792T (lt) 2011-05-31 2023-03-10 Biogen Ma Inc. Pdl rizikos vertinimo būdas
US20140113376A1 (en) 2011-06-01 2014-04-24 Rotem Sorek Compositions and methods for downregulating prokaryotic genes
US10166295B2 (en) 2011-06-02 2019-01-01 Opko Biologics Ltd. Pegylated OXM variants
ES2670596T3 (es) 2011-06-14 2018-05-31 Yeda Research And Development Co. Ltd. Terapia de combinación para prevenir la formación del DCIS y la progresión hasta cáncer de mama
JP2014523240A (ja) 2011-06-23 2014-09-11 カイイマ バイオ アグリテック リミテッド 部分的多重ゲノムまたは完全多重ゲノムを有する普通コムギ、その植物体または一部分、そのハイブリッドおよび生成物、ならびに、それらの作製方法および使用方法
WO2013010170A1 (fr) 2011-07-14 2013-01-17 Lovell Mark A Procédé de détection de la maladie d'alzheimer à partir d'un échantillon de sérum
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
CA3149018A1 (fr) 2011-07-18 2013-01-24 President And Fellows Of Harvard College Molecules manipulees ciblant un microbe et leurs utilisations
WO2013011507A1 (fr) 2011-07-20 2013-01-24 Kaiima Bio Agritech Ltd. Plantes de maïs ayant un génome partiellement ou totalement multiplié et utilisations de celles-ci
EP2550982A1 (fr) 2011-07-27 2013-01-30 Technion Research & Development Foundation Ltd. Dispositifs pour applications chirurgicales
HUE044154T2 (hu) 2011-08-04 2019-09-30 Yeda Res & Dev MIR-15 mikro-RNS, valamint az ezt tartalmazó készítmények kortikotropin-felszabadító hormonhoz kapcsolódó orvosi állapotok kezelésére
DK2739310T3 (en) 2011-08-05 2018-07-16 Res Found Dev Improved methods and compositions for modulating OLFML3-mediated angiogenesis
WO2013021389A2 (fr) 2011-08-09 2013-02-14 Yeda Research And Development Co.Ltd. Régulation à la baisse de mir-7 pour favoriser la différenciation des cellules bêta et la production d'insuline
EP2742352B1 (fr) 2011-08-12 2018-02-28 Siemens Healthcare Diagnostics Inc. Détection de stéroïdes sexuels
RU2014108930A (ru) 2011-08-14 2015-09-20 Каиима Био Агритех Лтд. Растения твердой пшеницы, обладающие частично или полностью умноженным геномом, и их применения
US9556281B2 (en) 2011-08-15 2017-01-31 The University Of Chicago Compositions and methods related to antibodies to staphylococcal protein A
EP2744828A4 (fr) 2011-08-16 2014-12-31 Univ Emory Agents spécifiques de liaison à jaml, anticorps, et leurs utilisations associées
US9959392B2 (en) 2011-09-07 2018-05-01 Yeda Research And Development Co. Ltd. Olfactory signature and odorant mixture having the same
ES2657552T3 (es) 2011-09-08 2018-03-05 Yeda Research And Development Co. Ltd. Nuevos biomarcadores de riesgo para el cáncer de pulmón
CA2848121C (fr) 2011-09-08 2022-07-05 Yeda Research And Development Co. Ltd. Lymphocytes t memoires centraux anti-tierce partie, leurs procedes de production et leur utilisation dans le cadre d'une transplantation ou du traitement d'une maladie
CN107739737A (zh) 2011-09-13 2018-02-27 孟山都技术公司 用于杂草控制的方法和组合物
AR088155A1 (es) 2011-09-13 2014-05-14 Monsanto Technology Llc Metodos y composiciones para el control de malezas
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
WO2013040057A1 (fr) 2011-09-13 2013-03-21 Monsanto Technology Llc Procédés et compositions de lutte contre les mauvaises herbes
AU2012308765B2 (en) 2011-09-13 2018-06-21 Monsanto Technology Llc Methods and compositions for weed control
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
WO2013054320A1 (fr) 2011-10-11 2013-04-18 Tel Hashomer Medical Research Infrastructure And Services Ltd. Anticorps dirigés contre la molécule d'adhésion cellulaire associée à l'antigène carcino-embryonnaire (ceacam)
HUE035999T2 (hu) 2011-10-21 2018-06-28 Augurex Life Sciences Corp Citrullinezett 14-3-3 peptidekbõl származó antigének és azok alkalmazásai a reumatoid artritisz diagnózisában
US9145559B2 (en) 2011-10-27 2015-09-29 Yeda Research And Development Co. Ltd. Methods of treating cancer
EP2773758B1 (fr) 2011-11-03 2017-06-07 Quark Pharmaceuticals, Inc. Compositions pour la neuroprotection
WO2013070821A1 (fr) 2011-11-08 2013-05-16 Quark Pharmaceuticals, Inc. Méthodes et compositions destinées à traiter des maladies, des troubles ou une lésion du système nerveux
US9736998B2 (en) 2011-11-23 2017-08-22 Danziger Dan Flower Farm Otomeria plants
US9617331B2 (en) 2011-11-27 2017-04-11 Yeda Research And Development Co. Ltd. Methods of regulating angiogenesis by administering agents which increase apoB-100 polypeptide
WO2013084190A1 (fr) 2011-12-08 2013-06-13 Yeda Research And Development Co. Ltd. Cellules pulmonaires fœtales de mammifères et leur utilisation thérapeutique
WO2013093921A1 (fr) 2011-12-20 2013-06-27 Collplant Ltd. Fibres de polymère synthétique enrobées de collagène
EP2794107B1 (fr) 2011-12-22 2021-08-11 Life Technologies Corporation Dispositif capillaire à écoulement latéral séquentiel pour la détermination d'un analyte
CA2859952C (fr) 2011-12-22 2023-04-04 Yeda Research And Development Co. Ltd. Polytherapie mise en oeuvre pour obtenir une prise de greffe stable et a long terme au moyen de protocoles specifiques d'appauvrissement des lymphocytes t/b
US9035039B2 (en) 2011-12-22 2015-05-19 Protiva Biotherapeutics, Inc. Compositions and methods for silencing SMAD4
AR089461A1 (es) 2011-12-28 2014-08-27 Kaiima Bio Agritech Ltd Una planta de sorghum cultivada que tiene un genoma parcial o totalmente multiplicado y usos de la misma
WO2013101758A1 (fr) 2011-12-29 2013-07-04 Baylor Research Institute Biomarqueurs de la maladie de kawasaki
JP2015509085A (ja) 2012-01-01 2015-03-26 キュービーアイ エンタープライゼズ リミテッドＱｂｉ Ｅｎｔｅｒｐｒｉｓｅｓ Ｌｔｄ． 治療剤および診断剤の選択的送達のためのｅｎｄｏ１８０を標的とする粒子
CN104136123B (zh) 2012-01-09 2017-03-01 精密公司 微流体反应器系统
US10139405B2 (en) 2012-01-24 2018-11-27 Cd Diagnostics, Inc. System for detecting infection in synovial fluid
WO2013114363A2 (fr) 2012-01-30 2013-08-08 Yeda Research And Development Co.Ltd. Agents antimicrobiens
WO2013114371A1 (fr) 2012-02-01 2013-08-08 Protalix Ltd. Formulation en poudre sèche de dnase i
US8771964B2 (en) 2012-02-02 2014-07-08 Siemens Healthcare Diagnostics Inc. Compositions and methods for detection of methadone metabolite
WO2013118120A2 (fr) 2012-02-06 2013-08-15 Rosetta Green Ltd. Polynucléotides isolés exprimant ou modulant des microarn ou des cibles de ceux-ci, plantes transgéniques comprenant ceux-ci et leurs utilisations dans l'amélioration de l'efficacité d'utilisation de l'azote, de la tolérance au stress abiotique, de la biomasse, de la vigueur ou du rendement d'une plante
CN104204192A (zh) 2012-02-13 2014-12-10 加米达细胞有限公司 间充质干细胞调理的基质及其产生和使用方法
CN104427994A (zh) 2012-02-14 2015-03-18 奥普科生物制品有限公司 长效凝血因子和生产它们的方法
JP2015513666A (ja) 2012-02-17 2015-05-14 エヌブイエス テクノロジーズ，インコーポレイティド アッセイへの適用のためのポリマー骨格
IN2014MN01806A (fr) 2012-02-19 2015-07-03 Protalix Ltd
JP6329911B2 (ja) 2012-02-22 2018-05-23 ブレインステム バイオテック リミテッド 星状膠細胞作製のためのミクロｒｎａ
EP2844745A2 (fr) 2012-02-22 2015-03-11 Brainstem Biotec Ltd. Génération de cellules souches neuronales et de motoneurones
AU2013222179B2 (en) 2012-02-24 2017-08-24 Arbutus Biopharma Corporat ion Trialkyl cationic lipids and methods of use thereof
CA2865714C (fr) 2012-02-29 2021-06-15 Chemocentryx, Inc. Sulfonamides de pyrazol-1-yl benzene convenant comme antagonistes de ccr9
EP2833714A1 (fr) 2012-03-01 2015-02-11 The State of Israel - Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) Plantes d'ail stérile mâle, descendance hybride de celles-ci et procédés de génération et d'utilisation de celles-ci
US9650665B2 (en) 2012-03-05 2017-05-16 Seegene, Inc. Detection of nucleotide variation on target nucleic acid sequence by PTO cleavage and extension assay
CN104411724B (zh) 2012-03-07 2018-08-31 耶达研究及发展有限公司 抑制静止素巯基氧化酶(qsox1)的组合物及其用途
RS58910B1 (sr) 2012-03-20 2019-08-30 Biogen Ma Inc Antitela koja neutrališu virus jcv
US9334308B2 (en) 2012-03-22 2016-05-10 Ramot At Tel-Aviv University Ltd. PLIF multimeric peptides and uses thereof
US20140178869A1 (en) 2012-04-05 2014-06-26 Advanced Cell Diagnostics, Inc. Detection of immunoglobulin light chain restriction by rna in situ hybridization
US9568431B2 (en) 2012-04-16 2017-02-14 Access Medical Systems, Ltd. Luminescent immunoassays for quantitating analytes having a wide concentration range
IN2014MN01886A (fr) 2012-04-18 2015-07-10 Univ Ramot
US9522945B2 (en) 2012-04-19 2016-12-20 Opko Biologics Ltd. Long-acting oxyntomodulin variants and methods of producing same
US20130280696A1 (en) 2012-04-23 2013-10-24 Elliott Millenson Devices and methods for detecting analyte in bodily fluid
WO2013160895A1 (fr) 2012-04-24 2013-10-31 Biokine Therapeutics Ltd. Peptides et leur utilisation dans le traitement du cancer du poumon à grandes cellules
NZ702282A (en) 2012-04-26 2016-07-29 Univ Chicago Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease
ES2683707T3 (es) 2012-05-02 2018-09-27 Ibis Biosciences, Inc. Secuenciación de ADN
ES2833524T3 (es) 2012-05-02 2021-06-15 Ibis Biosciences Inc Secuenciación de ADN
EP2846819B1 (fr) 2012-05-09 2017-05-03 Yeda Research and Development Co. Ltd. Variants de pro-domaine tace en tant qu'inhibiteur de tnf-a et leur utilisation médicale
ES2749200T3 (es) 2012-05-10 2020-03-19 Bioatla Llc Anticuerpos monoclonales multiespecíficos
EP2850086B1 (fr) 2012-05-18 2023-07-05 Pacific Biosciences Of California, Inc. Colorants hétéroarylcyanines
US8865158B2 (en) 2012-05-22 2014-10-21 Ramot At Tel-Aviv University Ltd. Bacteriophages for reducing toxicity of bacteria
MX369626B (es) 2012-05-24 2019-11-13 Mountgate Group Ltd Composiciones y metodos relacionados con la prevencion y el tratamiento de infecciones por rabia.
US10240161B2 (en) 2012-05-24 2019-03-26 A.B. Seeds Ltd. Compositions and methods for silencing gene expression
HUE051020T2 (hu) 2012-06-01 2021-01-28 Icahn School Med Mount Sinai A ceramid szintjei a fertõzések kezelésében és megelõzésében
US9731048B2 (en) 2012-06-03 2017-08-15 Ben-Gurion University Of The Negev Research And Development Authority Functionalized titanium binding peptides and implants coated with same
EA201492269A1 (ru) 2012-06-04 2016-02-29 Опко Байолоджикс Лтд. Пегилированные варианты oxm
AU2013277971B2 (en) 2012-06-22 2018-11-15 Htg Molecular Diagnostics, Inc. Molecular malignancy in melanocytic lesions
US20150140679A1 (en) 2012-06-27 2015-05-21 Siemens Healthcare Diagnostics Inc. Compositions and methods for liquid mixing assessment
US10023474B2 (en) 2012-07-03 2018-07-17 Nanospun Technologies Ltd. Methods for adsorption and biodegradation of petroleum
JP6387001B2 (ja) 2012-07-09 2018-09-05 ノバルティス アーゲー Ｃｄｋ阻害剤と関連するバイオマーカー
EP2875078B1 (fr) 2012-07-18 2017-12-20 President and Fellows of Harvard College Modification de surfaces pour une répulsion et une liaison ciblée simultanées de fractions désirées
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
WO2014018375A1 (fr) 2012-07-23 2014-01-30 Xenon Pharmaceuticals Inc. Cyp8b1 et ses utilisations dans des méthodes thérapeutiques et diagnostiques
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
HK1211039A1 (en) 2012-07-27 2016-05-13 The Board Of Trustees Of The University Of Illinois Engineering t-cell receptors
EP3594331A1 (fr) 2012-07-29 2020-01-15 Yeda Research and Development Co. Ltd. Utilisation de la voie de la glycine réductrice en vue de la génération de microorganismes formatotrophes et autotrophes
US20150159222A1 (en) 2012-07-31 2015-06-11 Novartis Ag Markers associated with human double minute 2 inhibitors
HK1205453A1 (en) 2012-07-31 2015-12-18 Yeda Research And Development Co. Ltd. Methods of diagnosing and treating motor neuron diseases
CA2877223C (fr) 2012-08-06 2019-08-27 Brainstorm Cell Therapeutics Ltd. Procedes de generation de cellules souches mesechymateuses qui secretent des facteurs neurotrophiques
CN105073132B (zh) 2012-08-23 2020-01-10 艾更斯司股份有限公司 结合158p1d7蛋白的抗体药物偶联物(adc)
WO2014035712A1 (fr) 2012-08-28 2014-03-06 Pierce Biotechnology, Inc. Composés de benzopyrylium
US20140068814A1 (en) 2012-09-03 2014-03-06 A.B. Seeds Ltd. Method of improving abiotic stress tolerance of plants and plants generated thereby
WO2014041544A1 (fr) 2012-09-12 2014-03-20 Ramot At Tel-Aviv University Ltd. Immunoparticules et procédés pour les produire et les utiliser
US11105809B2 (en) 2012-10-09 2021-08-31 Ramot At Tel-Aviv University Ltd. Methods and kits for predicting prognosis of cancer using soluble mortalin in blood
EP2906607A2 (fr) 2012-10-12 2015-08-19 NVS Technologies Inc. Polymères ayant des groupes réactifs orthogonaux et leurs utilisations
WO2014059442A2 (fr) 2012-10-12 2014-04-17 Arizona Board Agents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Réactifs à base d'anticorps qui reconnaissent spécifiquement des formes oligomériques toxiques de tau
EP2909341A2 (fr) 2012-10-18 2015-08-26 Oslo Universitetssykehus HF Biomarqueurs pour le cancer du col de l'utérus
US10226744B2 (en) 2012-10-19 2019-03-12 Danisco Us Inc Stabilization of biomimetic membranes
US20150354006A1 (en) 2012-10-19 2015-12-10 Novartis Ag Markers for acute lymphoblastic leukemia
US9395369B2 (en) 2012-10-19 2016-07-19 Regents Of The University Of Minnesota Guinea pig cytomegalovirus (CIDMTR strain)
EP2912062A1 (fr) 2012-10-24 2015-09-02 Yeda Research and Development Co. Ltd. Combinaisons d'anticorps ciblant les récepteurs du facteur de croissance épidermique pour traiter le cancer
WO2014066590A1 (fr) 2012-10-24 2014-05-01 Research Development Foundation Anticorps anti-jam-c et procédés pour le traitement du cancer
US9926564B2 (en) 2012-10-29 2018-03-27 Yeda Research And Development Co. Ltd. Aptamers, multimeric aptamers and uses thereof
CA2890906A1 (fr) 2012-11-16 2014-05-22 The Regents Of The University Of California Ligature pictet-spengler pour la modification chimique de proteines
HUE055348T2 (hu) 2012-11-20 2021-11-29 Opko Biologics Ltd Eljárás polipeptidek hidrodinamikus térfogatának növelésére gonadotropin karboxil-terminális peptidekhez való kapcsolással
EP2925359A2 (fr) 2012-11-29 2015-10-07 Yeda Research and Development Co., Ltd. Méthodes de prévention d'une métastase tumorale, de traitement et de pronostic du cancer, et d'identification d'agents susceptibles de constituer des inhibiteurs de métastase
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
US9121859B2 (en) 2012-12-04 2015-09-01 Siemens Healthcare Diagnostics Inc. Compounds and methods for determination of FKBP-binding immunosuppressant drugs
US10065186B2 (en) 2012-12-21 2018-09-04 Micronics, Inc. Fluidic circuits and related manufacturing methods
JP6935167B2 (ja) 2012-12-21 2021-09-15 ペルキネルマー ヘルス サイエンシーズ， インコーポレイテッド マイクロ流体使用のための低弾性フィルム
CN104919035B (zh) 2012-12-21 2017-08-11 精密公司 便携式荧光检测系统和微测定盒
UY35252A (es) 2013-01-01 2014-07-31 Seeds Ltd Ab MÉTODOS PARA INTRODUCIR dsRNA EN SEMILLAS DE PLANTAS PARA MODULAR LA EXPRESIÓN GENÉTICA
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
WO2014108854A1 (fr) 2013-01-09 2014-07-17 Fusimab Ltd. Anticorps anti-hgf et anti-ang2 monospécifiques, et anticorps anti-hgf/anti-ang2 bispécifiques
WO2014108850A2 (fr) 2013-01-09 2014-07-17 Yeda Research And Development Co. Ltd. Analyse de transcriptome à haut débit
EP2946207B1 (fr) 2013-01-17 2018-05-16 Novellusdx Ltd. Procédés et systèmes pour identifier des mutations conductrices spécifiques à un patient
US9970929B2 (en) 2013-01-18 2018-05-15 Ark Diagnostics, Inc. Voriconazole immunoassays
WO2014116721A1 (fr) 2013-01-22 2014-07-31 The Arizona Board Of Regents For And On Behalf Of Arizona State University Vecteur geminiviral pour l'expression du rituximab
US10077475B2 (en) 2013-01-24 2018-09-18 California Institute Of Technology FRET-based analytes detection and related methods and systems
US20140213471A1 (en) 2013-01-24 2014-07-31 California Institute Of Technology Chromophore-based characterization and detection methods
US9411930B2 (en) 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
CA2899865C (fr) 2013-02-01 2023-10-10 Kapil BHARTI Procede de generation de cellules epitheliales pigmentaires retiniennes (epr) a partir de cellules souches pluripotentes induites (cspi)
CN108624668B (zh) 2013-02-01 2022-12-02 加利福尼亚大学董事会 用于基因组组装及单体型定相的方法
US10000737B2 (en) 2013-02-04 2018-06-19 Ramot At Tel-Aviv University Ltd. Generation of cytotoxic tumor specific cell lines and uses thereof
ES2674704T3 (es) 2013-02-13 2018-07-03 Ark Diagnostics, Inc. Inmunoensayos de posaconazol
WO2014130846A1 (fr) 2013-02-22 2014-08-28 Seungpyo Hong Administration d'un médicament par voie transdermique faisant appel à des micelles amphiphiles « dendron-coil »
EP2770065B1 (fr) 2013-02-25 2017-12-13 Seegene, Inc. Détection de variations de nucléotides sur une séquence d'acide nucléique cible
WO2014136117A1 (fr) 2013-03-06 2014-09-12 Protalix Ltd. Utilisation de cellules végétales exprimant un inhibiteur du polypeptide tnf alpha en thérapie
CA2904035A1 (fr) 2013-03-06 2014-09-12 Protalix Ltd. Polypeptides inhibiteurs de tnf alpha, polynucleotides codant pour ceux-ci, cellules exprimant ceux-ci et leurs procedes de production
TWI582239B (zh) 2013-03-11 2017-05-11 諾華公司 與ｗｎｔ抑制劑相關之標記
EP2971106B1 (fr) 2013-03-11 2020-02-26 ELITechGroup, Inc. Procédés d'amplification isotherme par déplacement de brin en temps réel
US10114015B2 (en) 2013-03-13 2018-10-30 Meso Scale Technologies, Llc. Assay methods
CN105263329B (zh) 2013-03-13 2020-09-18 孟山都技术公司 用于杂草控制的方法和组合物
WO2014142575A1 (fr) 2013-03-13 2014-09-18 Seegene, Inc. Quantification d'un acide nucléique cible à l'aide d'analyse du pic de fusion
US10609930B2 (en) 2013-03-13 2020-04-07 Monsanto Technology Llc Methods and compositions for weed control
AU2014248759B2 (en) 2013-03-13 2020-02-27 Meso Scale Technologies, Llc. Improved assay methods
WO2014159063A1 (fr) 2013-03-14 2014-10-02 Elitech Holding B.V. Analogues de 3-alcynyl pyrazolopyrimidines fonctionnalisés utilisés en tant que bases universelles et procédés d'utilisation
AU2014236495A1 (en) 2013-03-14 2015-11-05 NVS Technologies, Inc. Surface oxidation for sequestering biomolecules and related methods
WO2014159242A1 (fr) 2013-03-14 2014-10-02 Novartis Ag Mutants de notch 3 et leurs utilisations
CN105246916A (zh) 2013-03-14 2016-01-13 诺华股份有限公司 针对notch 3的抗体
US9273349B2 (en) 2013-03-14 2016-03-01 Affymetrix, Inc. Detection of nucleic acids
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
US9944992B2 (en) 2013-03-15 2018-04-17 The University Of Chicago Methods and compositions related to T-cell activity
PT3524618T (pt) 2013-03-15 2023-06-06 Gladiator Biosciences Inc Domínios gla como agentes de marcação
US9347095B2 (en) 2013-03-15 2016-05-24 Bio-Rad Laboratories, Inc. Digital assays for mutation detection
EP2968469A4 (fr) 2013-03-15 2016-08-31 Longevity Biotech Inc Peptides comprenant des acides aminés non endogènes et procédés de fabrication et d'utilisation associés
WO2014153394A1 (fr) 2013-03-21 2014-09-25 Genisphere, Llc Administration cellulaire d'agents intercalants de l'adn
CA2907680A1 (fr) 2013-03-21 2014-09-25 Collplant Ltd. Compositions comprenant du collagene et prp pour la regeneration tissulaire
KR101403507B1 (ko) 2013-03-21 2014-06-09 주식회사 현일바이오 결핵균 및 비결핵 마이코박테리아의 선택적 검출 방법, 그리고 이를 이용한 키트
AU2014240733B2 (en) 2013-03-24 2018-11-22 Biolinerx Ltd. Methods of treating myeloid leukemia
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
US20140308751A1 (en) 2013-04-12 2014-10-16 Siemens Healthcare Diagnostics Inc. Assays for Analyte Homologs
US20160122758A1 (en) 2013-04-21 2016-05-05 Yeda Research And Development Co. Ltd. Agents for downregulation of the activity and/or amount of bcl-xl and/or bcl-w
CN105531365A (zh) 2013-04-23 2016-04-27 耶达研究及发展有限公司 分离的幼稚多能干细胞和产生所述细胞的方法
ES2671002T3 (es) 2013-04-25 2018-06-04 Yeda Research And Development Co., Ltd. Uso de péptidos inhibidores para el tratamiento de enfermedades inflamatorias
US20160091485A1 (en) 2013-04-25 2016-03-31 The Broad Institute, Inc. Markers for ezh2 inhibitors
AU2014262726B2 (en) 2013-05-07 2019-09-19 Revvity Health Sciences, Inc. Device for preparation and analysis of nucleic acids
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
EP2994532B1 (fr) 2013-05-07 2017-11-15 Micronics, Inc. Procédés de préparation d'échantillons d'acides nucléiques faisant appel à des minéraux argileux et à des solutions alcalines
WO2014186147A2 (fr) 2013-05-13 2014-11-20 Elitech Holding B.V. Pcr numérique à gouttelettes (ddpcr) utilisant de petites sondes courtes cannelées
WO2014190040A1 (fr) 2013-05-21 2014-11-27 President And Fellows Of Harvard College Compositions se liant à l'hème manipulées et leurs utilisations
US20160115231A1 (en) 2013-05-21 2016-04-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Treatment of mast cell related pathologies
DK3003493T3 (da) 2013-05-27 2020-01-13 Rakuto Bio Tech Ltd Enzymatisk system, som indeholder kosmetiske sammensætninger
WO2014193804A1 (fr) 2013-05-28 2014-12-04 Biogen Idec Ma Inc. Méthodes d'évaluation de risque de développement d'une lemp
ES2754177T3 (es) 2013-06-12 2020-04-16 Massachusetts Gen Hospital Métodos para la detección multiplexada de moléculas diana y sus usos
RU2689553C2 (ru) 2013-06-18 2019-05-28 Днатрикс, Инк. Лечение рака головного мозга онколитическим аденовирусом
WO2014207744A1 (fr) 2013-06-24 2014-12-31 Ramot At Tel-Aviv University Ltd. Échafaudage à base d'épiploon et système d'administration
WO2014210540A1 (fr) 2013-06-28 2014-12-31 Baylor Research Institute Immunothérapie par ciblage d'asgpr de cellules dendritiques pour la sclérose en plaques
KR101863943B1 (ko) 2013-07-15 2018-06-01 주식회사 씨젠 Ｐｔｏ 절단 및 연장-의존적 고정화 올리고뉴클레오타이드 혼성화를 이용한 타겟 핵산 서열의 검출
WO2015010026A2 (fr) 2013-07-19 2015-01-22 Monsanto Technology Llc Compositions et méthodes de lutte contre leptinotarsa
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
WO2015015489A1 (fr) 2013-07-30 2015-02-05 Biolinerx Ltd. Anticorps convenant au traitement du diabète et de maladies autoimmunes
EP3027220A1 (fr) 2013-08-01 2016-06-08 Agensys, Inc. Conjugués anticorps-médicament (adc) se liant à la protéine cd37
US9914775B2 (en) 2013-08-21 2018-03-13 The Board Of Regents Of The University Of Texas System Methods for treating inflammatory disorders or cancer metastasis by administering antibodies to connexin 43 (Cx43) hemichannels
ES2702674T3 (es) 2013-08-29 2019-03-04 Yeda Res & Dev Inhibidores selectivos de la isoforma alfa2 de Na,K-ATPasa y el uso para la reducción de la presión intraocular
RS62240B1 (sr) 2013-08-30 2021-09-30 Immunogen Inc Antitela i testovi za detekciju folatnog receptora 1
US20160251410A1 (en) 2013-09-03 2016-09-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions and methods for expressing recombinant polypeptides
IL228284A (en) 2013-09-03 2016-12-29 Technion Res & Dev Foundation Implants from cellular scaffolding and blood vessel stalk
WO2015033344A1 (fr) 2013-09-05 2015-03-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédés et nécessaires permettant d'inhiber la pathogénicité d'un streptocoque du groupe a (sga) ou d'un streptocoque du groupe g (sgg)
WO2015037009A1 (fr) 2013-09-16 2015-03-19 Plexicure Ltd. Protéines isolées capables de se lier à la plexine-a4, et procédés de production et d'utilisation
WO2015040609A1 (fr) 2013-09-17 2015-03-26 Yeda Research And Development Co. Ltd. Nouveaux peptides d'erk et leurs utilisations
CA2926180A1 (fr) 2013-10-01 2015-04-09 Kadimastem Ltd. Differenciation dirigee d'astrocytes a partir de cellules souches pluripotentes humaines pour utilisation dans le criblage de medicaments et le traitement de la sclerose lateraleamyotrophique (sla)
SG11201602540XA (en) 2013-10-03 2016-04-28 Oklahoma Med Res Found Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare
US9476884B2 (en) 2013-10-04 2016-10-25 University Of Massachusetts Hybridization- independent labeling of repetitive DNA sequence in human chromosomes
US11447814B2 (en) 2013-10-18 2022-09-20 Seegene, Inc. Detection of target nucleic acid sequence on solid phase by PTO cleavage and extension using HCTO assay
KR20240110069A (ko) 2013-10-21 2024-07-12 옵코 바이오로직스 리미티드 장시간-작용하는 폴리펩티드, 그의 생산 방법, 및 그의 투여 방법
US20150158926A1 (en) 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
US10767156B2 (en) 2013-10-24 2020-09-08 Yeda Research And Development Co., Ltd. Polynucleotides encoding BREX system polypeptides and methods of using same
WO2015061260A1 (fr) 2013-10-24 2015-04-30 Siemens Healthcare Diagnostics Inc. Dosages pour analytes macromoléculaires
US20160243187A1 (en) 2013-10-31 2016-08-25 Biokine Therapeutics Ltd. Methods of treating acute myeloid leukemia with a flt3 mutation
ES3008698T3 (en) 2013-11-04 2025-03-24 Greenlight Biosciences Inc Compositions and methods for controlling arthropod parasite and pest infestations
EP3065775B1 (fr) 2013-11-08 2020-09-30 The Board of Regents of the University of Texas System Anticorps vh4 dirigés contre les astrocytes et les neurones de la matière grise
WO2015073707A1 (fr) 2013-11-15 2015-05-21 The Board Of Trustees Of The Leland Stanford Junior University Procédés de traitement d'une insuffisance cardiaque avec des agonistes de récepteur 2 d'hypocrétine
CA2931220A1 (fr) 2013-11-20 2015-05-28 University Of Iowa Research Foundation Procedes et compositions pour le traitement de depots de substance amyloide
CN105899530B (zh) 2013-11-22 2020-05-08 伊利诺伊州大学理事会 工程化的高亲和力人类t细胞受体
ES2754207T3 (es) 2013-11-28 2020-04-16 Tel Hashomer Medical Res Infrastructure & Services Ltd Inhibidores de la ARN polimerasa I y usos de los mismos
EP3074044A2 (fr) 2013-11-28 2016-10-05 Yeda Research and Development Co., Ltd. Inhibiteurs de synaptojanine-2 et leurs utilisations
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
US10053712B2 (en) 2013-12-10 2018-08-21 Yeda Research And Development Co. Ltd. Use of enzymes which catalyze pyruvate synthesis from formate and acetyl-CoA and bacteria expressing same
WO2015089172A1 (fr) 2013-12-13 2015-06-18 Siemens Healthcare Diagnostics Inc. Agent de pré-traitement dans des dosages de non agglutination
US20150191744A1 (en) 2013-12-17 2015-07-09 University Of Massachusetts Cas9 effector-mediated regulation of transcription, differentiation and gene editing/labeling
WO2015095604A2 (fr) 2013-12-18 2015-06-25 President And Fellows Of Harvard College Méthodes et analyses associées à des cellules tumorales circulantes
WO2015095426A1 (fr) 2013-12-18 2015-06-25 Siemens Healthcare Diagnostics Inc. Détection d'une maladie endothéliale
WO2015094527A1 (fr) 2013-12-19 2015-06-25 Danisco Us Inc. Utilisation d'hydrophobines pour augmenter le transfert de gaz dans des processus de fermentation aérobie
ES2819865T3 (es) 2014-01-07 2021-04-19 Bioatla Llc Proteínas dirigidas a ortólogos
EP3094652B1 (fr) 2014-01-13 2021-09-29 Baylor Research Institute Nouveaux vaccins contre le vph et maladies liées au vph
US10334848B2 (en) 2014-01-15 2019-07-02 Monsanto Technology Llc Methods and compositions for weed control using EPSPS polynucleotides
CN106132992B (zh) 2014-01-29 2020-08-07 达娜-法勃肿瘤研究所公司 针对muc1-c/胞外结构域(muc1-c/ecd)的抗体
US20160340659A1 (en) 2014-01-30 2016-11-24 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. Actin binding peptides and compositions comprising same for inhibiting angiogenesis and treating medical conditions associated with same
EP3102192A2 (fr) 2014-02-03 2016-12-14 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Méthode d'élimination de cellules souches
CN111733231A (zh) 2014-02-05 2020-10-02 耶达研究及发展有限公司 用于治疗和诊断的微rna和包含所述微rna的组合物
WO2015118538A1 (fr) 2014-02-06 2015-08-13 Yeda Research And Development Co. Ltd. Anticorps anti cd84, compositions les comprenant et leurs utilisations
WO2015120273A1 (fr) 2014-02-07 2015-08-13 The General Hospital Corporation Diagnostic différentiel de néoplasmes hépatiques
US20170101633A1 (en) 2014-02-10 2017-04-13 Protalix Ltd. Method of maintaining disease stability in a subject having gaucher's disease
BR112016018489A2 (pt) 2014-02-11 2017-08-08 Brainstorm Cell Therapeutics Ltd Método de qualificação de células, população isolada de células-tronco mesenquimais, método de tratamento de uma doença imune ou inflamatória, e uso de células-tronco mesenquimais
WO2015123565A1 (fr) 2014-02-14 2015-08-20 The General Hospital Corporation Méthodes de diagnostic d'une maladie liée à l'igg4
US9540688B2 (en) 2014-02-19 2017-01-10 Personal Genomics, Inc. Real-time sequencing method for single molecule
WO2015131099A1 (fr) 2014-02-28 2015-09-03 The General Hospital Corporation Diagnostic du myélome multiple et du lymphome
CN106255882A (zh) 2014-03-03 2016-12-21 耶路撒冷希伯来大学伊森姆研究发展公司 用于检测铜绿假单胞菌的方法和装置
EP2923709A1 (fr) 2014-03-28 2015-09-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vaccin contre la malaria multi-composants-multi-étapes
WO2015147370A1 (fr) 2014-03-28 2015-10-01 Seegene, Inc. Détection de séquences d'acide nucléique cible à l'aide de différentes températures de détection
CN106413390B (zh) 2014-04-01 2019-09-27 孟山都技术公司 用于控制虫害的组合物和方法
EP3129075B1 (fr) 2014-04-10 2024-09-18 Bonus Therapeutics Ltd. Compositions pour la réparation des os
WO2015159293A2 (fr) 2014-04-14 2015-10-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédé et kit permettant de déterminer l'origine tissulaire ou cellulaire de l'adn
US10590467B2 (en) 2014-04-17 2020-03-17 Yeda Research And Development Co. Ltd. Methods and kits for analyzing DNA binding moieties attached to DNA
WO2015166484A1 (fr) 2014-04-27 2015-11-05 Ccam Therapeutics Ltd. Anticorps humanisés dirigés contre ceacam1
US11427647B2 (en) 2014-04-27 2022-08-30 Famewave Ltd. Polynucleotides encoding humanized antibodies against CEACAM1
US20160263166A1 (en) 2014-04-28 2016-09-15 Yeda Research And Development Co., Ltd. Microbiome response to agents
CN108064133A (zh) 2014-05-04 2018-05-22 佛利斯特创新有限公司 用于蚊虫控制的组合物和所述组合物的用途
EP3502698A1 (fr) 2014-05-05 2019-06-26 MicroBPlex, Inc. Milieux préparés avec des anticorps nouvellement synthétisés et leurs utilisations
JP2017515130A (ja) 2014-05-07 2017-06-08 エヌプレックス・ピーティーワイ・リミテッド 合成糸をベースとする側方流動イムノアッセイ
JP6875129B2 (ja) 2014-05-08 2021-05-19 ノボダイアックス， インコーポレイテッド 直接的な免疫組織化学アッセイ
CA2948360C (fr) 2014-05-09 2022-12-13 Biosearch Technologies, Inc. Extincteurs cosmiques
KR20250011724A (ko) 2014-05-15 2025-01-21 메소 스케일 테크놀러지즈, 엘엘시 개선된 분석 방법
WO2015179435A1 (fr) 2014-05-19 2015-11-26 Bayer Healthcare Llc Anticorps monoclonaux humanisés optimisés dirigés contre la protéine c activée et leurs utilisations
WO2015177800A2 (fr) 2014-05-22 2015-11-26 Yeda Research And Development Co. Ltd. Micro-organismes recombinés pouvant fixer le carbone
US20170253881A1 (en) 2014-06-02 2017-09-07 Technion Research & Development Foundation Limited Compositions and methods of selectively inhibiting irp1 and treating inflammation
EP3149155B1 (fr) 2014-06-02 2020-09-23 Kadimastem Ltd. Procédés d'induction de la myélinisation et de maturation des oligodendrocytes
EP2955517A1 (fr) 2014-06-10 2015-12-16 Siemens Healthcare Diagnostics Products GmbH Procédé de stabilisation d'échantillons de liquide corporel par administration de détergent
CN106795515B (zh) 2014-06-23 2021-06-08 孟山都技术公司 用于经由rna干扰调控基因表达的组合物和方法
US20170183376A1 (en) 2014-06-24 2017-06-29 Insight Biopharmaceuticals Ltd. Methods of purifying antibodies
US11807857B2 (en) 2014-06-25 2023-11-07 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
KR20170041192A (ko) 2014-06-25 2017-04-14 텔 하쇼머 메디컬 리서치 인프라스트럭쳐 앤드 서비시스 리미티드． 암 줄기세포 마커의 동정 및 진단 및 치료를 위한 그의 사용
EP3160448B1 (fr) 2014-06-26 2025-08-06 Ramot at Tel-Aviv University Ltd. Formulations de liposome pour l'administration d'acides nucléiques
ES2853525T3 (es) 2014-06-27 2021-09-16 Siemens Healthcare Diagnostics Inc Parejas de unión específicas para epímeros de vitamina D en ensayos de vitamina D
BR112016030560A8 (pt) 2014-06-27 2021-07-13 Siemens Healthcare Diagnostics Inc parceiros de ligação específicos para epímeros de vitamina d, anticorpo e método para separar uma vitamina d epimérica de uma amostra suspeita de conter uma vitamina d epimérica
WO2016005985A2 (fr) 2014-07-09 2016-01-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Méthode pour reprogrammer des cellules
DK3169343T3 (da) 2014-07-15 2020-06-22 Yissum Research And Development Company Of The Hebrew Univ Of Jerusalem Ltd Isolerede cd44-polypeptider og anvendelser heraf
EP3172562B1 (fr) 2014-07-21 2019-03-13 Novellusdx Ltd. Procédés et systèmes pour déterminer un indice oncogénique de mutations spécifiques d'un patient
CA2955411A1 (fr) 2014-07-21 2016-01-28 Novellusdx Ltd. Procedes de determination d'une reponse a un medicament de mutations specifiques a un patient
AU2015296700B2 (en) 2014-07-29 2021-10-21 Monsanto Technology Llc Compositions and methods for controlling insect pests
WO2016016894A1 (fr) 2014-07-30 2016-02-04 Yeda Research And Development Co. Ltd. Milieux pour la culture de cellules souches pluripotentes
WO2016019360A1 (fr) 2014-08-01 2016-02-04 Dovetail Genomics Llc Marquage d'acides nucléiques pour l'assemblage de séquences
AU2015302870B2 (en) 2014-08-14 2021-12-23 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
WO2016030899A1 (fr) 2014-08-28 2016-03-03 Yeda Research And Development Co. Ltd. Méthodes de traitement de la sclérose latérale amyotrophique
EP2992895A1 (fr) 2014-09-08 2016-03-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vaccin contre la malaria multi-composants-multi-étapes
EP3191523B1 (fr) 2014-09-08 2019-08-07 Yeda Research and Development Co., Ltd. Compositions et procédés de traitement d'un cancer résistant à un inhibiteur de la tyrosine kinase (tki)
US10526416B2 (en) 2014-09-08 2020-01-07 Yeda Research And Development Co. Ltd. Anti-HER3 antibodies and uses of same
WO2016038550A1 (fr) 2014-09-11 2016-03-17 Novartis Ag Inhibition de prmt5 dans le traitement de maladies liées à une déficience en mtap
CA2972739A1 (fr) 2014-09-11 2016-03-17 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Procedes de production de mogrosides et compositions les comprenant et leurs utilisations
IL234638A0 (en) 2014-09-14 2014-12-02 Yeda Res & Dev NMDA receptor antagonists for the treatment of Gaucher disease
US10759860B2 (en) 2014-09-16 2020-09-01 Synermore Biologics Co., Ltd. Anti-EGFR antibody and uses of same
US10174320B2 (en) 2014-09-21 2019-01-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Downregulating miR-132 for the treatment of lipid related disorders
ES2971041T3 (es) 2014-10-06 2024-06-03 Chemocentryx Inc Terapia combinada de inhibidores del receptor 9 de quimiocina C-C (CCR9) y anticuerpos bloqueadores anti-integrina alfa4beta7 para el tratamiento de la enfermedad inflamatoria intestinal
EP3207156A1 (fr) 2014-10-13 2017-08-23 Life Technologies Corporation Procédés, kits et compositions pour déterminer des nombres de copies de gène
DE102015220401B4 (de) 2014-10-20 2022-12-29 Gen-Probe Incorporated Erythrozyten-Lyselösung
CN107075534A (zh) 2014-10-24 2017-08-18 丹尼斯科美国公司 使用三肽基肽酶制备醇的方法
EP3209773B1 (fr) 2014-10-24 2020-03-18 DuPont Nutrition Biosciences ApS Tripeptidyl-peptidases tolérant la proline et leurs utilisations
ES2965744T3 (es) 2014-11-13 2024-04-16 Enzootic Holdings Ltd Inversión sexual funcional de crustáceos decápodos hembras
EP3221470B1 (fr) 2014-11-17 2019-08-14 Yeda Research and Development Co., Ltd. Procédé d'analyse de microbiome
WO2016079736A2 (fr) 2014-11-17 2016-05-26 Yeda Research And Development Co. Ltd. Procédés de traitement de maladies associées à une fonction mitochondriale
CN107001455B (zh) 2014-11-19 2022-03-01 皇家飞利浦有限公司 利用hnl的诊断方法
BR112017010555A2 (pt) 2014-11-20 2018-02-27 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd composições e métodos para produção de polipeptídeos com padrão de glicosilação modificado em células vegetais
JP6860483B2 (ja) 2014-11-26 2021-04-14 テクノロジー イノベーション モメンタム ファンド（イスラエル）リミテッド パートナーシップＴｅｃｈｎｏｌｏｇｙ Ｉｎｎｏｖａｔｉｏｎ Ｍｏｍｅｎｔｕｍ Ｆｕｎｄ（ｉｓｒａｅｌ）Ｌｉｍｉｔｅｄ Ｐａｒｔｎｅｒｓｈｉｐ 細菌遺伝子の標的化削減
CA2968808A1 (fr) 2014-11-27 2016-06-02 Danziger Innovations Ltd. Construction d'acide nucleique pour l'edition de genome
WO2016089920A1 (fr) 2014-12-01 2016-06-09 The Broad Institute, Inc. Procédé de détermination in situ de proximité d'acide nucléique
US10479997B2 (en) 2014-12-01 2019-11-19 Novartis Ag Compositions and methods for diagnosis and treatment of prostate cancer
AU2015360694B2 (en) 2014-12-08 2021-10-14 Berg Llc Use of markers including filamin a in the diagnosis and treatment of prostate cancer
PH12021552108A1 (en) 2014-12-10 2022-05-11 Opko Biologics Ltd Methods of producing long acting ctp-modified growth hormone polypeptides
WO2016092554A1 (fr) 2014-12-11 2016-06-16 Memed Diagnostics Ltd. Combinaisons de marqueurs de diagnostic d'infections et leurs méthodes d'utilisation
WO2016092555A2 (fr) 2014-12-11 2016-06-16 Yeda Research And Development Co. Ltd. Polypeptides de phosphotriestérase isolés, polynucléotides codant pour ceux-ci et utilisations de ceux-ci dans le traitement ou la prévention des dommages associés à l'exposition aux organophosphates
US9988670B2 (en) 2014-12-12 2018-06-05 Elitechgroup B.V. Methods and compositions for detecting antibiotic resistant bacteria
US10266903B2 (en) 2014-12-12 2019-04-23 Elitechgroup, Inc. Methods and compositions for detecting antibiotic resistant bacteria
WO2016102950A1 (fr) 2014-12-23 2016-06-30 4D Pharma Research Limited Immunomodulation
HRP20180847T1 (hr) 2014-12-23 2018-08-24 4D Pharma Research Limited Pirinski polipeptid i imunološka modulacija
WO2016103269A1 (fr) 2014-12-23 2016-06-30 Ramot At Tel-Aviv University Ltd. Populations de cellules progénitrices neuronales et leurs procédés de production et d'utilisation
US11891622B2 (en) 2014-12-30 2024-02-06 Cell Cure Neurosciences Ltd. RPE cell populations and methods of generating same
WO2016108240A1 (fr) 2014-12-30 2016-07-07 Cell Cure Neurosciences Ltd. Évaluation de populations de cellules épithéliales pigmentaires rétiniennes
KR102359257B1 (ko) 2014-12-30 2022-02-07 셀 큐어 뉴로사이언시스 리미티드 망막 질환의 치료 방법
EP3240896A1 (fr) 2015-01-04 2017-11-08 Protalix Ltd. Dnase modifiée et ses utilisations
WO2016116935A1 (fr) 2015-01-21 2016-07-28 Yeda Research And Development Co. Ltd. Utilisation de la rasa2 en tant que marqueur pronostique et thérapeutique pour un mélanome
CA2974101A1 (fr) 2015-01-22 2016-07-28 Monsanto Technology Llc Compositions et methodes de lutte contre leptinotarsa
EP3256490A1 (fr) 2015-02-09 2017-12-20 Research Development Foundation Polypeptides ayant un domaine fc d'immunoglobuline modifié manifestant une activation du complément améliorée
JP6777966B2 (ja) 2015-02-17 2020-10-28 ダブテイル ゲノミクス エルエルシー 核酸配列アセンブリ
US10479825B2 (en) 2015-02-25 2019-11-19 Vanderbilt University Antibody-mediated neutralization of Marburg virus
WO2016135732A1 (fr) 2015-02-26 2016-09-01 Yeda Research And Development Co. Ltd. Procédé favorisant la pousse des cheveux
EP3268038B1 (fr) 2015-03-09 2021-05-05 Agensys, Inc. Conjugués anticorps-médicament (cam) se liant aux protéines flt3
WO2016142948A1 (fr) 2015-03-11 2016-09-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Oligonucléotides leurres pour le traitement de maladies
CN107614700A (zh) 2015-03-11 2018-01-19 布罗德研究所有限公司 基因型和表型偶联
IL237852A0 (en) 2015-03-19 2016-03-24 Yeda Res & Dev Antibodies against amphigoline, medical preparations containing them and their use
US10028659B2 (en) 2015-03-26 2018-07-24 Verily Life Sciences Llc Aptamer-based sensors, implantable devices and detection system
GB2554572B (en) 2015-03-26 2021-06-23 Dovetail Genomics Llc Physical linkage preservation in DNA storage
US11136401B2 (en) 2015-03-27 2021-10-05 University Of Southern California Car t-cell therapy directed to LHR for the treatment of solid tumors
US20180064748A1 (en) 2015-03-27 2018-03-08 Yeda Research And Development Co. Ltd. Methods of treating motor neuron diseases
US20180071369A1 (en) 2015-03-31 2018-03-15 Yeda Research And Development Co. Ltd. Glutamate oxaloacetate transaminase 1 (got1), preparations and methods of generating same and uses thereof
US9612534B2 (en) 2015-03-31 2017-04-04 Tokyo Electron Limited Exposure dose homogenization through rotation, translation, and variable processing conditions
EP3277260B1 (fr) 2015-04-01 2021-05-12 The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) Extraits végétaux de crassifolium erodium l'her et leurs utilisations
ES2912276T3 (es) 2015-04-07 2022-05-25 Ela Pharma Ltd Composiciones para tratar y/o prevenir necrosis celular o tisular que seleccionan como diana específicamente catepsina C y/o CELA1 y/o CELA3A y/o enzimas estructuralmente relacionadas con las mismas
ES2971094T3 (es) 2015-04-07 2024-06-03 Polyskope Labs Detección de uno o más patógenos
EP3081575A1 (fr) 2015-04-12 2016-10-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Anticorps anti-plasmodium pour parasite
ES2924731T3 (es) 2015-04-15 2022-10-10 Biosearch Tech Inc Sondas con extintor doble
AU2016255725B2 (en) 2015-04-27 2021-09-23 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center EGR1 targeting molecules for the treatment of inflammatory and hyperproliferative conditions
AU2016255724B2 (en) 2015-04-29 2020-05-14 The State of Israel, Ministry of Agriculture and Rural Development Agricultural Research Organization (ARO) (Volcani Center) Anti-phytopathogenic compositions
WO2016174652A1 (fr) 2015-04-30 2016-11-03 Technion Research & Development Foundation Limited Récepteurs antigéniques chimériques et méthodes d'utilisation correspondantes
US11845928B2 (en) 2015-05-04 2023-12-19 Tsinghua University Methods and kits for fragmenting DNA
EP3091026B1 (fr) 2015-05-08 2019-02-20 Centrillion Technology Holdings Corporation Terminateurs réversibles à liaison disulfure
EP3294280A1 (fr) 2015-05-11 2018-03-21 Yeda Research and Development Co., Ltd. Inhibiteurs de citrine pour le traitement du cancer
EP3298141A4 (fr) 2015-05-17 2019-01-09 The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center Compositions et méthodes de traitement du cancer
EP3297663B1 (fr) 2015-05-18 2025-11-12 Agensys, Inc. Anticorps qui se lient aux protéines axl
WO2016187354A1 (fr) 2015-05-18 2016-11-24 Agensys, Inc. Anticorps se liant à des protéines axl
RS60032B1 (sr) 2015-05-18 2020-04-30 Saga Diagnostics Ab Detekcija ciljne nukleinske kiseline i varijanti
WO2016185457A1 (fr) 2015-05-19 2016-11-24 Yeda Research And Development Co. Ltd. Méthodes pour favoriser la lymphagiogenèse
EP3297680A2 (fr) 2015-05-20 2018-03-28 Yeda Research and Development Co. Ltd Procédé destiné à cibler des cellules sénescentes
JP2018515564A (ja) 2015-05-21 2018-06-14 イェダ リサーチ アンド ディベロップメント カンパニー リミテッドＹｅｄａ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏ．Ｌｔｄ． 健康増進のための細菌群
KR20180014754A (ko) 2015-05-29 2018-02-09 옵코 바이오로직스 리미티드 페길화된 옥신토모둘린 변이체
US10883103B2 (en) 2015-06-02 2021-01-05 Monsanto Technology Llc Compositions and methods for delivery of a polynucleotide into a plant
US10655136B2 (en) 2015-06-03 2020-05-19 Monsanto Technology Llc Methods and compositions for introducing nucleic acids into plants
AU2016270474A1 (en) 2015-06-04 2018-01-04 University Of Southern California Lym-1 and Lym-2 targeted CAR cell immunotherapy
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
EP3662917A1 (fr) 2015-06-15 2020-06-10 4D Pharma Research Limited Compositions comprenant des souches bactériennes
RS59446B1 (sr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Blautia stercosis i wexlerae za upotrebu u lečenju inflamatornih i autoimunskih bolesti
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
PL3650033T3 (pl) 2015-06-15 2022-05-16 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
WO2016203476A1 (fr) 2015-06-18 2016-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédés et compositions pour le diagnostic et le traitement d'un cancer urothélial
ES2917884T3 (es) 2015-06-18 2022-07-12 Yeda Res & Dev Protocolos de acondicionamiento y uso de los mismos para la regeneración de tejidos
EP3988113A1 (fr) 2015-06-19 2022-04-27 OPKO Biologics Ltd. Facteurs de coagulation à action prolongée et ses procédés de production
CA2990822A1 (fr) 2015-06-26 2016-12-29 Dupont Nutrition Biosciences Aps Aminopeptidases pour hydrolysats de proteines
AU2016291558A1 (en) 2015-07-10 2018-02-08 West Virginia University Markers of stroke and stroke severity
PL3322425T3 (pl) 2015-07-16 2023-10-09 Yeda Research And Development Co., Ltd. Zmodyfikowane genetycznie, skierowane przeciwko osobie trzeciej centralne limfocyty T pamięci i ich zastosowanie w immunoterapii
CN116196426A (zh) 2015-07-16 2023-06-02 百欧肯治疗有限公司 治疗癌症的组合物及方法
EP3907231A1 (fr) 2015-07-19 2021-11-10 Yeda Research and Development Co., Ltd. Inhibiteurs séléctifs de na,k-atpase contenant des isoformes alpha2 et leur utilisation pour réduire la pression intraoculaire
US10877045B2 (en) 2015-07-21 2020-12-29 Saint Louis University Compositions and methods for diagnosing and treating endometriosis-related infertility
CN107846936B (zh) 2015-07-22 2021-06-01 芙图法尔马国际有限公司 蜜蜂可摄取组成物及使用其生产蜂蜜的方法与由此生产的蜂蜜
US11230696B2 (en) 2015-07-29 2022-01-25 Hadasit Medical Research Services And Development Ltd. Large scale production of retinal pigment epithelial cells
WO2017021963A1 (fr) 2015-08-03 2017-02-09 Biokine Therapeutics Ltd. Agents de liaison de cxcr4 pour le traitement de maladies
WO2017021961A1 (fr) 2015-08-04 2017-02-09 Yeda Research And Development Co. Ltd. Procédés de criblage pour riborégulateurs et atténuateurs
CA2994416A1 (fr) 2015-08-04 2017-02-09 Cd Diagnostics, Inc. Procedes de detection d'une necrose liee a une reaction locale indesirable sur les tissus (altr)
US11066642B2 (en) 2015-08-05 2021-07-20 Cell Cure Neurosciences Ltd Preparation of retinal pigment epithelium cells
US11090337B2 (en) 2015-08-05 2021-08-17 Cell Cure Neurosciences Ltd Preparation of photoreceptors for the treatment of retinal diseases
CN108289928B (zh) 2015-08-06 2024-09-17 哈佛大学校长及研究员协会 改进的微生物-结合分子和其用途
US10639350B2 (en) 2015-08-10 2020-05-05 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods and pharmaceutical compositions for improving wound healing using CD24
WO2017025967A1 (fr) 2015-08-13 2017-02-16 Forrest Innovations Ltd. Formulations et compositions d'administration d'acides nucléiques à des cellules végétales
US11214800B2 (en) 2015-08-18 2022-01-04 The Broad Institute, Inc. Methods and compositions for altering function and structure of chromatin loops and/or domains
WO2017033188A1 (fr) 2015-08-24 2017-03-02 Yeda Research And Development Co. Ltd. Huile et biocarburant d'origine algale et leurs procédés de production
WO2017033152A1 (fr) 2015-08-25 2017-03-02 Prothena Biosciences Limited Procédés de détection d'alpha-synucléine phosphorylée
WO2017040380A2 (fr) 2015-08-28 2017-03-09 Research Development Foundation Variants de fc d'anticorps modifiés
WO2017040813A2 (fr) 2015-09-02 2017-03-09 University Of Massachusetts Détection de loci de gènes comprenant des répétitions matricielles de crispr et/ou des acides ribonucléiques mono-guides polychromatiques
US10765706B2 (en) 2015-09-03 2020-09-08 University Of South Florida Method of stem cell delivery into the brain during chronic disease using blood brain barrier permeabilizers
US11453864B2 (en) 2015-09-08 2022-09-27 University Of Massachusetts DNase H activity of Neisseria meningitidis Cas9
WO2017042816A1 (fr) 2015-09-10 2017-03-16 Yeda Research And Development Co. Ltd. Ablation de cellules dendritiques dont le test est positif pour la perforine, dans le traitement du cancer
WO2017053567A1 (fr) 2015-09-22 2017-03-30 Delta Tm Technologies Conception de systèmes tampons personnalisés spécifiques à une protéine
CN108368554B (zh) 2015-09-29 2022-09-09 Htg分子诊断有限公司 弥漫性大b细胞淋巴瘤(dlbcl)亚型分型的方法
SG11201802912PA (en) 2015-10-10 2018-05-30 Intrexon Corp Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12
US11078528B2 (en) 2015-10-12 2021-08-03 Advanced Cell Diagnostics, Inc. In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto
JP7300831B2 (ja) 2015-10-19 2023-06-30 ダブテイル ゲノミクス エルエルシー ゲノムアセンブリ、ハプロタイプフェージング、および標的に依存しない核酸検出のための方法
WO2017072757A1 (fr) 2015-10-25 2017-05-04 Yeda Research And Development Co. Ltd. Anticorps ciblant la quiescine sulfhydryle oxydase (qsox1) et leurs utilisations
EP3368661B1 (fr) 2015-10-26 2025-01-22 Cell Cure Neurosciences Ltd. Procédé de production de cellules d'épithélium pigmentaire de la rétine
JP7078538B2 (ja) 2015-10-27 2022-05-31 ジェイ ファーマ、インコーポレイティッド がんの治療のためのカンナビジオール及び第二の治療剤を含む組成物
IL242380A0 (en) 2015-10-29 2016-02-01 Yeda Res & Dev A method for inducing the division of cardiomyocytes and treating heart diseases
US20180303974A1 (en) 2015-11-03 2018-10-25 Ariel-University Research And Development Company Ltd. Compositions for regeneration and repair of neural tissue
HUE067793T2 (hu) 2015-11-09 2024-11-28 Childrens Hospital Philadelphia Glipikán 2 mint rákmarker és terápiás célpont
WO2017081689A1 (fr) 2015-11-11 2017-05-18 Ramot At Tel-Aviv University Ltd. Procédés de détection de la 5-hydroxyméthylcytosine et diagnostic du cancer
PL3209310T3 (pl) 2015-11-20 2018-08-31 4D Pharma Research Limited Kompozycja zawierająca szczepy bakteryjne
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
EP4231015B1 (fr) 2015-11-30 2024-10-30 Kadimastem Ltd. Procédés de différenciation et de purification de cellules endocrines pancréatiques
EP3383911B1 (fr) 2015-12-02 2021-01-20 STCube & Co. Inc. Anticorps et molécules se liant de manière immunospécifique à btn1a1 et leurs utilisations thérapeutiques
KR102815803B1 (ko) 2015-12-02 2025-06-05 주식회사 에스티사이언스 당화된 btla(b- 및 t-림프구 약화인자)에 특이적인 항체
EP3176183A1 (fr) 2015-12-02 2017-06-07 Yeda Research and Development Co. Ltd Compositions et procédés pour traiter un cancer non résistant à un inhibiteur de la tyrosine kinase (tki)
ES2902477T3 (es) 2015-12-04 2022-03-28 Univ Texas Péptidos SLC45A2 para inmunoterapia
ES2984278T3 (es) 2015-12-16 2024-10-29 Univ Ramot Partículas que comprenden epiplón descelularizado
JOP20200228A1 (ar) 2015-12-21 2017-06-16 Novartis Ag تركيبات وطرق لخفض تعبير البروتين tau
EP3393524B1 (fr) 2015-12-22 2022-04-06 The Regents of The University of Colorado, A Body Corporate Protection d'arn de la dégradation à l'aide d'arn viraux modifiés
EP3397344A4 (fr) 2015-12-28 2019-08-28 B.G. Negev Technologies and Applications Ltd. at Ben-Gurion University Composition et méthode pour le traitement de la sclérose latérale amyotrophique
WO2017118985A1 (fr) 2016-01-06 2017-07-13 Yeda Research And Development Co. Ltd. Compositions et méthodes pour le traitement d'affections malignes, autoimmunes et inflammatoires
WO2017122203A1 (fr) 2016-01-11 2017-07-20 Technion Research & Development Foundation Limited Méthodes de détermination du pronostic de septicémie et traitement associé
JP7019580B2 (ja) 2016-01-21 2022-02-15 ザ ステイト オブ イスラエル ミニストリー オブ アグリカルチャー アンド ルーラル ディベロップメント アグリカルチュラル リサーチ オーガニゼイション （エー．アール．オー．） （ボルカニ センター） 単為結実植物およびその製造方法
IL243838A (en) 2016-01-28 2017-07-31 Sp Nano Ltd The composition containing sp1 protein and carbon nanoparticles and its uses
IL243839B (en) 2016-01-28 2018-01-31 Sp Nano Ltd Conductive wires
US11261433B2 (en) 2016-01-31 2022-03-01 Hadasit Medical Research Services And Development Ltd. Autosomal-identical pluripotent stem cell populations having non-identical sex chromosomal composition and uses thereof
CN108884137B (zh) 2016-02-04 2022-04-05 耶达研究及发展有限公司 肽及其在治疗与突变型p53相关的疾病、病症或病况中的用途
WO2017139415A2 (fr) 2016-02-11 2017-08-17 Qiagen Waltham, Inc. Composés piégeurs pour un séquençage par synthèse amélioré
CN109196113B (zh) 2016-02-11 2022-10-04 奇根科学有限责任公司 合成测序中的多酚添加剂
EP3414346B1 (fr) 2016-02-14 2019-11-13 Yeda Research and Development Co. Ltd. Diagnostic basé sur le microbiome, prédiction et traitement de l'obésité de rechute
WO2017138008A2 (fr) 2016-02-14 2017-08-17 Yeda Research And Development Co. Ltd. Procédés de modulation de l'exocytose de protéines et utilisations associées en thérapie
MX2018009984A (es) 2016-02-16 2019-01-21 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Análogos no proteínicos de fenilananina para la inhibicion del crecimiento de cianobacterias y plantas.
US12338435B2 (en) 2016-02-19 2025-06-24 Code Biotherapeutics, Inc. Nucleic acid carriers and therapeutic methods of use
US20200200735A9 (en) 2016-02-22 2020-06-25 Ursure, Inc. System and method for detecting therapeutic agents to monitor adherence to a treatment regimen
WO2017145162A1 (fr) 2016-02-23 2017-08-31 Chaya Brodie Production de cellules souches cancéreuses et leur utilisation
KR102744506B1 (ko) 2016-02-23 2024-12-18 더브테일 제노믹스 엘엘씨 게놈 어셈블리를 위한 페이징된 판독 세트의 생성 및 반수체형 페이징
WO2017147060A1 (fr) 2016-02-25 2017-08-31 Dupont Nutrition Biosciences Aps Procédé de production d'un hydrolysat protéique utilisant la tripeptidyl-peptidase aspergillus
JP7098527B2 (ja) 2016-02-26 2022-07-11 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム コネキシン（Ｃｘ）４３ヘミチャネル結合抗体及びその使用
IL296874A (en) 2016-03-01 2022-11-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Antibodies specific for the human poliovirus receptor
CN114959084A (zh) 2016-03-03 2022-08-30 米密德诊断学有限公司 分析rna用于诊断感染类型
MD3313423T2 (ro) 2016-03-04 2019-10-31 4D Pharma Plc Compoziții care conțin tulpini bacteriene de Blautia pentru tratamentul hipersensibilității viscerale
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
US20190216891A1 (en) 2016-03-06 2019-07-18 Yeda Research And Development Co., Ltd. Method for modulating myelination
IL244649A0 (en) 2016-03-17 2016-06-30 Yeda Res & Dev Methods for the isolation of barrel-like proteases and the identification of peptides that are cleaved by Alidan
US10458995B2 (en) 2016-03-25 2019-10-29 Muralidhar Reddy Moola Combinatorial synthesis and biomarker development
WO2017172518A1 (fr) 2016-03-29 2017-10-05 Stcube, Inc. Anticorps à fonction double spécifiques de pd-l1 glycosylée et leurs procédés d'utilisation
EP3436480A4 (fr) 2016-03-30 2019-11-27 Musc Foundation for Research Development Méthodes pour le traitement et le diagnostic du cancer par le ciblage d'une protéine à prédominance de répétitions de glycoprotéine a (garp) et la mise en uvre d'une immunothérapie efficace seule ou en association
EP3440461A4 (fr) 2016-04-06 2019-11-06 Technion Research & Development Foundation Limited Prédiction de la réponse anti-tnf dans des biopsies de côlon avec les proportions de cellules immunitaires infiltrantes
US10421785B2 (en) 2016-04-11 2019-09-24 Bar-Ilan University Delta receptor agonist peptides and use thereof
EP3736332B1 (fr) 2016-04-27 2025-02-12 Gen-Probe Incorporated Réactif de lyse de cellules sanguines
WO2017194589A1 (fr) 2016-05-10 2017-11-16 Vib Vzw Inhibition du dysfonctionnement synaptique précoce à médiation par tau
SG11201810088SA (en) 2016-05-13 2018-12-28 Dovetail Genomics Llc Recovering long-range linkage information from preserved samples
WO2017201064A1 (fr) 2016-05-16 2017-11-23 President And Fellows Of Harvard College Couplage de biomolécule aqueuse sur des surfaces activées par plasma de co2
WO2017203520A1 (fr) 2016-05-22 2017-11-30 Yeda Research And Development Co. Ltd. Méthodes d'utilisation de cellules pulmonaires pour transplantation et induction de tolérance
IL245861A0 (en) 2016-05-25 2016-09-04 Yeda Res & Dev Use of substances to treat drug-resistant tumors
WO2017208247A1 (fr) 2016-06-02 2017-12-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Essai pour l'élimination de résidus de méthyle-cytosine de l'adn
WO2017212476A1 (fr) 2016-06-05 2017-12-14 Tel Hashomer Medical Research Infrastructure And Services Ltd. Nouvelles molécules destinées au traitement de l'inflammation
EP3465200A4 (fr) 2016-06-05 2020-07-08 Berg LLC Systèmes et procédés de stratification de patient et identification de biomarqueurs potentiels
EP3468610A1 (fr) 2016-06-09 2019-04-17 OPKO Biologics Ltd. Formulation d'oxyntomoduline à action prolongée, et procédés de production et procédés d'administration de cette dernière
US11859232B2 (en) 2016-06-19 2024-01-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Screening for chemotherapy resistance in human haploid cells
AU2017280943B2 (en) 2016-06-20 2023-05-18 Emory University Circular RNAs and their use in immunomodulation
EP3475414B1 (fr) 2016-06-27 2025-03-26 Yeda Research and Development Co. Ltd Cellules veto generer de cellules t memoires
JP7112966B2 (ja) 2016-06-30 2022-08-04 シーメンス ヘルシニアーズ ネイザランド ビー．ブイ． 複数の細胞を含む体液試料内で分析物を検出するための装置、システム及び方法
MA54568A (fr) 2016-07-01 2021-10-27 Carlsberg As Substitutions de nucléotides prédéterminées
EP4141448A1 (fr) 2016-07-10 2023-03-01 MeMed Diagnostics Ltd. Signatures protéiques permettant de faire la distinction entre des infections bactériennes et virales
CN109804245B (zh) 2016-07-10 2022-10-25 米密德诊断学有限公司 感染的早期诊断
IL246722A0 (en) 2016-07-11 2016-09-29 Yeda Res & Dev Combination therapy to increase endogenous nitric oxide (no) synthesis
AU2017296175B2 (en) 2016-07-11 2023-11-02 Bonus Therapeutics Ltd. Cell compositions for tissue regeneration
CN109563145B (zh) 2016-07-11 2024-01-26 Opko生物科学有限公司 长效凝血因子及其制备方法
CN109714962A (zh) 2016-07-11 2019-05-03 耶路撒冷希伯来大学的益生研究开发有限公司 用于在体外培养细胞的系统和方法
TWI802545B (zh) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
US11708421B2 (en) 2016-07-18 2023-07-25 Ramot At Tel-Aviv University Ltd. Modular platform for targeted therapeutics
US11746152B2 (en) 2016-07-20 2023-09-05 Stcube, Inc. Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated PD-L1
US10829528B2 (en) 2016-07-20 2020-11-10 Vib Vzw Therapeutic agents for neurological and psychiatric disorders
WO2018020489A1 (fr) 2016-07-24 2018-02-01 Yeda Research And Development Co. Ltd. Méthodes et kits pour analyser des fragments de liaison à l'adn liés à l'adn
WO2018029682A1 (fr) 2016-08-08 2018-02-15 Ramot At Tel-Aviv University Ltd. Systèmes bactériens servant à analyser des polypeptides ubiquitinylés
EP3504553B1 (fr) 2016-08-10 2022-04-20 Memed Diagnostics Ltd. Système et procédé d'analyse de données biologiques
US10633706B2 (en) 2016-08-10 2020-04-28 Ramot At Tel-Aviv University Ltd. Analysis of methylation status and copy number
EP3496730B1 (fr) 2016-08-14 2022-05-25 Ramot at Tel-Aviv University Ltd. Exosomes dérivés de cellules mésenchymateuses pour traiter des troubles neurologiques
IL247368A0 (en) 2016-08-18 2016-11-30 Yeda Res & Dev Diagnostic and therapeutic uses of exosomes
WO2018037416A1 (fr) 2016-08-25 2018-03-01 Yeda Research And Development Co. Ltd. Procédés et compositions pour le traitement de maladies auto-immunes
CN109890205A (zh) 2016-08-28 2019-06-14 以色列农业和农村发展部农业研究组织(范卡尼中心) 控制植物中的真菌感染的方法
JP2020501506A (ja) 2016-09-07 2020-01-23 イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム エルティーディー． 抗ＮＫｐ４６抗体およびその治療的使用
WO2018051347A1 (fr) 2016-09-14 2018-03-22 Yeda Research And Development Co. Ltd. Crisp-seq, procédé intégré pour séquençage massivement parallèle d'arn unicellulaire et criblages regroupés par crispr
US11385241B2 (en) 2016-09-29 2022-07-12 Memed Diagnostics Ltd. Methods of prognosis and treatment
IL248468A0 (en) 2016-10-13 2017-01-31 Technion Res & Dev Foundation Use of caspase-3 inhibitors and caspase-3 activators in the manufacture of medicament for treating cancer and wound healing
IL248385A0 (en) 2016-10-18 2017-02-01 Yeda Res & Dev Treatment of circadian rhythm disorder
EP3534953A4 (fr) 2016-11-02 2020-10-07 Vanderbilt University Anticorps contre le virus zika humain et leurs procédés d'utilisation
EP3535409B1 (fr) 2016-11-04 2024-03-20 CD Diagnostics, Inc. Détection directe de micro-organismes dans des échantillons de patient par dosage immunologique
CN110121563A (zh) 2016-11-09 2019-08-13 奇根科学有限责任公司 在边合成边测序中作为成像试剂的光保护混合物
WO2018087759A1 (fr) 2016-11-10 2018-05-17 Yeda Research And Development Co. Ltd. Phosphotriestérases destinés au traitement ou à prévention des dommages associés à l'exposition aux organophosphates
US10973809B2 (en) 2016-11-23 2021-04-13 Chemocentryx, Inc. Method of treating focal segmental glomerulosclerosis
JP2019535298A (ja) 2016-11-28 2019-12-12 イェダ リサーチ アンド ディベロップメント カンパニー リミテッドＹｅｄａ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏ．Ｌｔｄ． 単離ポリヌクレオチドおよびポリペプチドおよび関心のある発現産物を発現させるためにそれらを使用する方法
WO2018100431A1 (fr) 2016-11-29 2018-06-07 Genomic Vision Procédé de conception d'un ensemble de séquences polynucléotidiques destiné à l'analyse d'événements spécifiques dans une région génétique d'intérêt
WO2018100574A1 (fr) 2016-11-30 2018-06-07 Yeda Research And Development Co. Ltd. Méthodes de traitement de maladies et de la toxicité hépathique
EP3548106B1 (fr) 2016-12-01 2023-01-04 Ramot at Tel-Aviv University Ltd. Traitement combiné pour lésions nerveuses
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
US10851410B2 (en) 2017-01-04 2020-12-01 Mgi Tech Co., Ltd. Nucleic acid sequencing using affinity reagents
US11555178B2 (en) 2017-01-18 2023-01-17 Yeda Research And Development Co. Ltd. Genetically modified veto cells and use of same in immunotherapy
CN116908476A (zh) 2017-01-25 2023-10-20 St创新诊断有限公司 诊断恶性疾病的方法
RU2665631C2 (ru) 2017-01-25 2018-09-03 Общество с ограниченной ответственностью "Секвойя Дженетикс" Способ специфической идентификации последовательностей днк
CA3049778C (fr) 2017-01-26 2024-06-18 Oklahoma Medical Research Foundation Biomarqueurs de l'activite, de l'intensite et de l'eruption de la maladie du lupus erythemateux dissemine
WO2018137705A1 (fr) 2017-01-26 2018-08-02 Zai Lab (Shanghai) Co., Ltd. Unité de liaison à l'antigène cd47 et ses utilisations
CA3051466A1 (fr) 2017-01-31 2018-08-09 Vanderbilt University Generation d'anticorps monoclonaux ige specifiques d'allergenes et d'helminthes humains pour une utilisation diagnostique et therapeutique
IL250479A0 (en) 2017-02-06 2017-03-30 Sorek Rotem Genetically engineered cells expressing a disarm system that confers resistance to phages and methods for their production
AU2018217992B2 (en) 2017-02-08 2023-12-14 Hadasit Medical Research Services And Development Ltd. Photoreceptor cells for the treatment of retinal diseases
IL250916A0 (en) 2017-03-02 2017-06-29 Geiger Benjamin Methods for growing t cells in culture and their use
US11179413B2 (en) 2017-03-06 2021-11-23 Novartis Ag Methods of treatment of cancer with reduced UBB expression
WO2018167780A1 (fr) 2017-03-12 2018-09-20 Yeda Research And Development Co. Ltd. Méthodes de diagnostic et de traitement du cancer
WO2018167778A1 (fr) 2017-03-12 2018-09-20 Yeda Research And Development Co. Ltd. Procédés de diagnostic et de pronostic du cancer
US20200085882A1 (en) 2017-03-16 2020-03-19 Lineage Cell Therapeutics, Inc. Methods for measuring therapeutic effects of retinal disease therapies
IL269821B2 (en) 2017-04-05 2024-02-01 Yeda Res & Dev In vitro culture system and methods for its use
CN108823287B (zh) 2017-04-28 2019-04-12 厦门大学 一种检测靶核酸序列的方法
IL252151A0 (en) 2017-05-07 2017-07-31 Fainzilber Michael Treatment of stress disorders
US20210003570A1 (en) 2017-05-10 2021-01-07 Rowan University Diagnostic biomarkers for detecting, subtyping, and/or assessing progression of multiple sclerosis
US12091445B2 (en) 2017-05-10 2024-09-17 Ariel Scientific Innovations Ltd. Methods of purifying antibodies
US11714089B2 (en) 2017-05-21 2023-08-01 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Combination of markers for diagnosing cancer
CA3064171A1 (fr) 2017-05-22 2018-11-29 4D Pharma Research Limited Compositions comprenant des souches bacteriennes
WO2018216011A1 (fr) 2017-05-23 2018-11-29 Technion Research & Development Foundation Limited Agents inhibant la dimérisation de gads et leurs procédés d'utilisation
WO2018215782A1 (fr) 2017-05-24 2018-11-29 4D Pharma Research Limited Compositions comprenant des souches bactériennes
GB201708662D0 (en) 2017-05-31 2017-07-12 Tropic Biosciences Uk Ltd Compositions and methods for increasing shelf-life of banana
WO2018220582A1 (fr) 2017-05-31 2018-12-06 Tropic Biosciences UK Limited Méthodes de sélection de cellules comprenant des événements d'édition de génome
KR20200015602A (ko) 2017-05-31 2020-02-12 주식회사 에스티큐브앤컴퍼니 Btn1a1에 면역특이적으로 결합하는 항체 및 분자 및 이의 치료적 용도
GB201708665D0 (en) 2017-05-31 2017-07-12 Tropic Biosciences Uk Ltd Compositions and methods for increasing extractability of solids from coffee beans
KR20250139417A (ko) 2017-05-31 2025-09-23 주식회사 에스티큐브앤컴퍼니 Btn1a1에 면역특이적으로 결합하는 항체 및 분자를 사용하여 암을 치료하는 방법
KR20200026209A (ko) 2017-06-06 2020-03-10 주식회사 에스티큐브앤컴퍼니 Btn1a1 또는 btn1a1-리간드에 결합하는 항체 및 분자를 사용하여 암을 치료하는 방법
ES2826394T3 (es) 2017-06-09 2021-05-18 Siemens Healthcare Diagnostics Products Gmbh Ensayo de activación para el diagnóstico de una trombocitopenia inducida por heparina
WO2018229764A1 (fr) 2017-06-13 2018-12-20 Yeda Research And Development Co. Ltd. Traitement de la sclérose en plaques avancée ou progressive
JP6840272B2 (ja) 2017-06-14 2021-03-10 フォーディー ファーマ リサーチ リミテッド４Ｄ Ｐｈａｒｍａ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ 細菌株を含む組成物
MA49373B1 (fr) 2017-06-14 2021-02-26 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
HRP20201629T1 (hr) 2017-06-14 2020-12-25 4D Pharma Research Limited Sastavi koji sadrže bakterijski soj roda megasphaera i njihove upotrebe
US12140592B2 (en) 2017-06-16 2024-11-12 Oklahoma Medical Research Foundation Biomarkers for assessing risk of transitioning to systemic lupus erythematosus classification and disease pathogenesis
WO2019012544A1 (fr) 2017-07-13 2019-01-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Stratégie de pcr en gouttelettes à double sonde pour la détection spécifique de molécules d'adn circulantes spécifiques d'un tissu
WO2019012543A1 (fr) 2017-07-13 2019-01-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Cibles d'adn à titre de marqueurs de méthylation spécifiques de tissu
US20200165671A1 (en) 2017-07-13 2020-05-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Detecting tissue-specific dna
US10768185B2 (en) 2017-07-20 2020-09-08 Trustees Of Boston University Tenofovir detection assay
WO2019016772A2 (fr) 2017-07-21 2019-01-24 Novartis Ag Compositions et procédés permettant de traiter un cancer
IL253642A0 (en) 2017-07-24 2017-09-28 Seger Rony Combined treatment for cancer
ES2862434T3 (es) 2017-08-02 2021-10-07 Siemens Healthcare Diagnostics Products Gmbh Prueba de unión para el diagnóstico de trombocitopenia inducida por heparina
EP3665283A4 (fr) 2017-08-08 2021-04-21 Technology Innovation Momentum Fund (Israel) Limited Partnership Protéine tronquée résistante au chloramphénicol et ses utilisations
IL253984A0 (en) 2017-08-14 2017-09-28 Yeda Res & Dev Immunotherapy against aranviruses that bind through transferrin receptor 1 (tfr1
US10677728B2 (en) 2017-08-17 2020-06-09 Elitechgroup B.V. Duplex stabilizing fluorescence quenchers for nucleic acid probes
WO2019038761A1 (fr) 2017-08-21 2019-02-28 Savicell Diagnostic Ltd. Procédés pour le diagnostic et le traitement du cancer du poumon
US11692166B2 (en) 2017-08-23 2023-07-04 Technion Research & Development Foundation Limited Compositions and methods for improving alcohol tolerance in yeast
PE20200797A1 (es) 2017-08-25 2020-08-10 Five Prime Therapeutics Inc Anticuerpos que se unen especificamente a b7-h4 humana
WO2019045532A2 (fr) 2017-08-31 2019-03-07 Seegene, Inc. Évaluation de la performance de composants à l'aide d'une paire d'amorces de formation de dimères
EP3626745A4 (fr) 2017-09-01 2021-03-17 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Anticorps bispécifique recombinant
PE20201263A1 (es) 2017-09-05 2020-11-19 Gladiator Biosciences Inc Suministro de cargas utiles a las celulas madre
WO2019055825A1 (fr) 2017-09-15 2019-03-21 The Regents Of The University Of California Inhibition de l'aminoacylase 3 (aa3) dans le traitement du cancer
ES2915576T3 (es) 2017-09-19 2022-06-23 Tropic Biosciences Uk Ltd Modificación de la especificidad de moléculas de ARN no codificantes de plantas para silenciar la expresión génica
CA3075956A1 (fr) 2017-09-19 2019-03-28 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Oiseaux a edition de genome
AU2018341454B2 (en) 2017-09-26 2023-09-28 The Regents Of The University Of California Compositions and methods for treating cancer
WO2019066461A2 (fr) 2017-09-29 2019-04-04 Seegene, Inc. Détection de séquences d'acides nucléiques cibles par analyse par clivage et extension de pto
WO2019071054A1 (fr) 2017-10-04 2019-04-11 The Broad Institute, Inc. Procédés et compositions permettant de modifier la fonction et la structure de boucles et/ou de domaines de chromatine
US11525002B2 (en) 2017-10-11 2022-12-13 Board Of Regents, The University Of Texas System Human PD-L1 antibodies and methods of use therefor
MX386699B (es) 2017-10-11 2025-03-19 Chemocentryx Inc Tratamiento de glomerulosclerosis segmentaria focal con antagonistas ccr2
US12178787B2 (en) 2017-10-12 2024-12-31 Board Of Regents, The University Of Texas System T cell receptors for immunotherapy
CN111565731B (zh) 2017-10-24 2024-03-08 达莉亚·伊兰妮 治疗缺血性疾病的方法
JP2021502125A (ja) 2017-11-09 2021-01-28 ピンテオン セラピューティクス インコーポレイテッド ヒト化コンホメーション特異的リン酸化タウ抗体の作製および使用のための方法および組成物
IL255664A0 (en) 2017-11-14 2017-12-31 Shachar Idit Hematopoietic stem cells with enhanced properties
US20200390800A1 (en) 2017-11-29 2020-12-17 Ramot At Tel-Aviv University Ltd. Methods of preventing or treating neurogenic shock
AR114936A1 (es) 2017-11-29 2020-11-11 Weedout Ltd Composiciones, kits y métodos para controlar la maleza del género amaranthus
EP3716993A1 (fr) 2017-12-03 2020-10-07 Yeda Research and Development Co. Ltd Traitement d'une maladie cardiaque ischémique
CN109870581B (zh) 2017-12-04 2021-05-04 厦门万泰凯瑞生物技术有限公司 一种定量检测HBsAg的试剂盒及方法
CA3085324A1 (fr) 2017-12-15 2019-06-20 Syngenta Participations Ag Ligands non-anticorps pour la detection de proteines cibles
EP3723785A1 (fr) 2017-12-17 2020-10-21 Yeda Research and Development Co. Ltd Modulateurs du complexe signalosome cop9 (csn) et leurs utilisations
WO2019130313A1 (fr) 2017-12-28 2019-07-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Procédé pour reproduire des rythmes circadiens sur une puce microfluidique
WO2019156758A2 (fr) 2018-01-05 2019-08-15 Vanderbilt University Neutralisation à médiation par anticorps du virus chikungunya
EP3514541A1 (fr) 2018-01-17 2019-07-24 Siemens Healthcare Diagnostics Products GmbH Procédé de détermination quantitative d'un inhibiteur du tnf-alpha thérapeutique
IL257225A (en) 2018-01-29 2018-04-09 Yeda Res & Dev Treatment of sarcoma
CA3087291A1 (fr) 2018-01-29 2019-08-01 Lavie Bio Ltd. Preparations microbiennes vegetales, compositions et formulations les comprenant et leurs utilisations
IL257269A (en) 2018-01-31 2018-04-09 Olender Tsviya Signaling is directed to the endoplasmic reticulum
US12378592B2 (en) 2018-01-31 2025-08-05 Dovetail Genomics, Llc. Sample prep for DNA linkage recovery
EP3749368A1 (fr) 2018-02-08 2020-12-16 Yeda Research and Development Co. Ltd Procédés d'identification et d'utilisation d'agents pour traiter des maladies associées à un dysfonctionnement de la barrière intestinale
EP3749689A1 (fr) 2018-02-08 2020-12-16 Yeda Research and Development Co. Ltd Inhibiteurs du protéasome 20s
WO2019155041A1 (fr) 2018-02-12 2019-08-15 Vib Vzw ANTICORPS COMPLEXES Gβγ ET LEURS UTILISATIONS
WO2019165077A1 (fr) 2018-02-21 2019-08-29 Five Prime Therapeutics, Inc. Formulations d'anticorps b7-h4
WO2019165217A1 (fr) 2018-02-22 2019-08-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cd153 et/ou cd30 dans une infection
WO2019162945A1 (fr) 2018-02-23 2019-08-29 Carmel Haifa University Economic Corporation Ltd. Méthodes de traitement d'un trouble de la mémoire et d'un dysfonctionnement cognitif
EP3759493A1 (fr) 2018-02-28 2021-01-06 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Méthodes de diagnostic et de traitement du cancer de la vessie
KR20200144094A (ko) 2018-03-02 2020-12-28 파이브 프라임 테라퓨틱스, 인크. B7-h4 항체 및 이의 사용 방법
WO2019175869A1 (fr) 2018-03-12 2019-09-19 Yeda Research And Development Co. Ltd Traitement d'une maladie cardiaque
AU2019239568B2 (en) 2018-03-23 2025-09-11 Board Of Regents, The University Of Texas System Dual specificity antibodies to human PD-L1 and PD-L2 and methods of use therefor
EP3768726B1 (fr) 2018-03-23 2024-10-30 Board of Regents, The University of Texas System Anticorps à double spécificité pour pd-l1 et pd-l2 et leurs procédés d'utilisation
CN112236131A (zh) 2018-03-29 2021-01-15 技术研究及发展基金有限公司 包含pten抑制剂的囊泡及其用途
IL258467A (en) 2018-03-29 2018-07-04 Ilana Kolodkin Gal Methods of disrupting a biofilm and/or preventing formation of same
EP3774047A1 (fr) 2018-03-29 2021-02-17 Yeda Research and Development Co. Ltd Utilisation de gradients de champ électrique pour commander l'expression génique
WO2019199643A1 (fr) 2018-04-09 2019-10-17 Bio-Techne Corporation Procédés d'amélioration supplémentaire de l'amplification de signal pour la détection in situ d'acides nucléiques
CN112004941B (zh) 2018-04-20 2023-10-27 Seegene株式会社 用于检测样品中的多个靶核酸序列的方法及装置
EP3785732A4 (fr) 2018-04-24 2022-02-23 Ampsource Biopharma Shanghai Inc. Anticorps dirigé contre tim-3 et application associée
GB201807192D0 (en) 2018-05-01 2018-06-13 Tropic Biosciences Uk Ltd Compositions and methods for reducing caffeine content in coffee beans
WO2019213276A1 (fr) 2018-05-02 2019-11-07 Novartis Ag Régulateurs de cellules souches pluripotentes humaines et leurs utilisations
WO2019220441A1 (fr) 2018-05-15 2019-11-21 Hadasit Medical Research Services And Development Ltd. Compositions et méthodes de traitement du cancer résistant à un agent anticancéreux
IL259392A (en) 2018-05-15 2018-08-01 Yeda Res & Dev Vaccination with cancer neoantigens
WO2019229745A1 (fr) 2018-05-27 2019-12-05 Biolinerx Ltd. Agi-134 combinée à un inhibiteur de point de contrôle pour le traitement de tumeurs solides
US11155713B2 (en) 2018-05-29 2021-10-26 Elitechgroup, Inc. Carborhodamine compounds and methods of preparation thereof
WO2019234750A1 (fr) 2018-06-07 2019-12-12 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Procédés de régénération et de transformation de cannabis
CN112424365A (zh) 2018-06-07 2021-02-26 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 核酸构建体及其使用方法
TW202016144A (zh) 2018-06-21 2020-05-01 日商第一三共股份有限公司 包括cd3抗原結合片段之組成物及其用途
WO2020003311A1 (fr) 2018-06-25 2020-01-02 Yeda Research And Development Co. Ltd. Systèmes et procédés permettant d'améliorer l'efficacité de l'édition génomique
AU2019297677B2 (en) 2018-07-04 2024-11-07 Ukko Inc. Methods of de-epitoping wheat proteins and use of same for the treatment of celiac disease
EP3818529A2 (fr) 2018-07-08 2021-05-12 Yeda Research and Development Co. Ltd Évaluation spécifique à une personne de la sensibilité aux probiotiques
KR20210044220A (ko) 2018-07-11 2021-04-22 카 메디컬 리미티드 SIRPalpha-4-1BBL 변이체 융합 단백질 및 이의 사용 방법
SG11202012773QA (en) 2018-07-11 2021-01-28 Immunity Pharma Ltd Peptide compounds and therapeutic uses of same
KR20210042430A (ko) 2018-07-31 2021-04-19 콜플랜트 리미티드 담배 형질전환 이벤트 및 이의 검출 방법 및 용도
IL261156A (en) 2018-08-14 2020-02-27 Fass Deborah Chimeric quiescin sulfhydryl oxidase (qsox1) antibodies and uses of same
CN113227359A (zh) 2018-08-24 2021-08-06 耶达研究及发展有限公司 调节m2巨噬细胞极化的方法及其在治疗中的用途
WO2020056077A1 (fr) 2018-09-13 2020-03-19 The Board Of Regents Of The University Of Texas System Nouveaux anticorps anti-lilrb4 et leurs utilisations
EP3852759A2 (fr) 2018-09-20 2021-07-28 Yeda Research and Development Co. Ltd Méthodes de traitement de la sclérose latérale amyotrophique
EP3856225A1 (fr) 2018-09-25 2021-08-04 BioLineRx Ltd. Procédés de sélection d'un traitement contre un cancer associé aux récepteurs cxcr4
CN113195511A (zh) 2018-09-28 2021-07-30 生捷科技控股公司 二硫键连接的可逆终止剂
KR102220701B1 (ko) 2018-09-28 2021-03-03 (주)나노헬릭스 형광기반의 다중 융해 분석을 이용한 증폭 산물의 다중 분석방법
MY209774A (en) 2018-10-15 2025-08-03 Univ Massachusetts Programmable dna base editing by nme2cas9-deaminase fusion proteins
WO2020081204A1 (fr) 2018-10-18 2020-04-23 Oklahoma Medical Research Foundation Biomarqueurs d'indice immunitaire d'activité de maladie du lupus érythémateux disséminé (sle) qui caractérise une activité de maladie
BR112021007690A2 (pt) 2018-10-22 2021-08-10 Shanghai GenBase Biotechnology Co., Ltd. anticorpo anti-cldn18.2 e uso do mesmo
CA3115887A1 (fr) 2018-10-23 2020-04-30 Glycardial Diagnostics, S.L. Anticorps specifiques de l'apoj glycosylee et leurs utilisations
IL262658A (en) 2018-10-28 2020-04-30 Memorial Sloan Kettering Cancer Center Prevention of age related clonal hematopoiesis and diseases associated therewith
WO2020102660A1 (fr) 2018-11-16 2020-05-22 President And Fellows Of Harvard College Molécules et procédés d'immunodétection améliorée de petites molécules, telles que l'histamine
CN111196851B (zh) 2018-11-20 2021-11-16 厦门万泰凯瑞生物技术有限公司 针对人抗缪勒管激素的特异性抗体及其应用
IL263184A (en) 2018-11-21 2020-05-31 Yarden Yosef Method of treating cancer and compositions for same
JP7478149B2 (ja) 2018-11-28 2024-05-02 オレゴン ヘルス アンド サイエンス ユニバーシティー 治療用第ｘｉｉ因子抗体
CA3121170A1 (fr) 2018-11-30 2020-06-04 Caris Mpi, Inc. Profilage moleculaire de nouvelle generation
US12441776B2 (en) 2018-11-30 2025-10-14 Eirgen Pharma Ltd. Oxyntomodulin peptide analog formulations
US12478571B2 (en) 2018-12-17 2025-11-25 Pontis Biologics, Inc. Enzyme based compositions and methods for removing dental calculi
EP3904386A4 (fr) 2018-12-28 2022-09-07 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Anticorps et son utilisation
EP3914698B1 (fr) 2019-01-23 2024-12-11 Yeda Research and Development Co. Ltd Milieux de culture pour cellules souches pluripotentes
US20220056498A1 (en) 2019-01-25 2022-02-24 President And Fellows Of Harvard College Compositions and method for synthesizing nucleic acids
SG11202107720UA (en) 2019-01-31 2021-08-30 Agency Science Tech & Res Cnx/erp57 inhibitor for use in the treatment or prevention of cancer
IL264768A (en) 2019-02-10 2020-08-31 Sagi Irit ANTI-MATRIX METALLOPROTEINASE 7 (MMP-7) inhibitory antibody and its use
IL264854A (en) 2019-02-14 2020-08-31 Bahat Anat Spt5 inhibitors and methods of use thereof
CN114555825A (zh) 2019-02-15 2022-05-27 领先细胞医疗诊断有限公司 用于通过原位杂交进行核酸的多路复用检测的方法
JP2022521010A (ja) 2019-02-21 2022-04-04 イッスム・リサーチ・デベロプメント・カムパニー・オブ・ザ・ヘブリュー・ユニバシティー・オブ・エルサレム リミテッド 薬物誘導性腎毒性を減少させるための方法
EP3927807A1 (fr) 2019-02-21 2021-12-29 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Procédés de génération d'organoïdes pour criblage à haut rendement de médicaments
MX2021010611A (es) 2019-03-05 2021-11-12 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo Aves con genoma editado.
WO2020185763A1 (fr) 2019-03-11 2020-09-17 Memorial Sloan Kettering Cancer Center Anticorps cd22 et leurs procédés d'utilisation
GB201903519D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Introducing silencing activity to dysfunctional rna molecules and modifying their specificity against a gene of interest
GB201903520D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Modifying the specificity of non-coding rna molecules for silencing genes in eukaryotic cells
GB201903521D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd No title
IL265486A (en) 2019-03-19 2020-09-30 Yeda Res & Dev Bistable type ii opsins and uses thereof
WO2020194317A1 (fr) 2019-03-28 2020-10-01 Yeda Research And Development Co. Ltd. Méthode de traitement de troubles liés aux lipides
WO2020202142A2 (fr) 2019-03-31 2020-10-08 Yeda Research And Development Co. Ltd. Composés anti-viraux et anti-tumoraux
WO2020211674A1 (fr) 2019-04-16 2020-10-22 四川科伦博泰生物医药股份有限公司 Anticorps anti-fxi/fxia et son utilisation
US20200377951A1 (en) 2019-04-30 2020-12-03 Chondrial Therapeutics, Inc. Frataxin-sensitive markers for determining effectiveness of frataxin replacement therapy
IL266433B (en) 2019-05-02 2020-11-30 Sagi Irit Preparations containing the propeptide of lysyl oxidase and their uses
WO2020230133A1 (fr) 2019-05-13 2020-11-19 Yeda Research And Development Co. Ltd. Biomarqueurs de micro-adn acellulaire pour le pronostic et le diagnostic de maladies neurodégénératives
IL266728B (en) 2019-05-19 2020-11-30 Yeda Res & Dev Identification of recurrent mutant neopeptides
AU2020279080B2 (en) 2019-05-22 2025-11-27 Hadasit Medical Research Services And Development Ltd. Methods of culturing human pluripotent cells
CN114599675B (zh) 2019-05-28 2024-08-16 上海科技大学 用于治疗clouston型外胚层发育不良2的组合物和方法
JP7668233B2 (ja) 2019-06-12 2025-04-24 ハダシット メディカル リサーチ サービシーズ アンド ディベロップメント リミテッド オリゴデンドロサイトの産生方法
EP3983540A1 (fr) 2019-06-16 2022-04-20 Yeda Research and Development Co. Ltd Méthode de stabilisation de l'arn intracellulaire
JP7653924B2 (ja) 2019-06-27 2025-03-31 ダブテイル ゲノミクス エルエルシー 近接ライゲーションのための方法および組成物
US20220251193A1 (en) 2019-06-27 2022-08-11 Ramot At Tel-Aviv University Ltd. Semaphorin 3a antibodies and uses thereof
EP3994268A1 (fr) 2019-07-04 2022-05-11 Ukko Inc. Alpha gliadine sans épitope et son utilisation pour la gestion de la maladie coeliaque et de la sensibilité au gluten
EP3997114A1 (fr) 2019-07-11 2022-05-18 KAHR Medical Ltd. Hétérodimères et procédés d'utilisation correspondants
WO2021009740A1 (fr) 2019-07-16 2021-01-21 Ramot At Tel-Aviv University Ltd. Compositions et procédés pour le traitement de la tuberculose
IL268111A (en) 2019-07-16 2021-01-31 Fainzilber Michael Methods of treating pain
WO2021016062A1 (fr) 2019-07-19 2021-01-28 The Children's Hospital Of Philadelphia Récepteurs antigéniques chimériques contenant des domaines de liaison au glypicane 2
CA3145278A1 (fr) 2019-07-26 2021-02-04 Vanderbilt University Anticorps monoclonaux humains diriges contre l'enterovirus d68
CA3147575A1 (fr) 2019-07-29 2021-02-04 Yeda Research And Development Co. Ltd. Procedes de traitement et de diagnostic du cancer du poumon
WO2021019536A1 (fr) 2019-07-30 2021-02-04 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Méthodes de régulation de la synthèse de cannabinoïdes chez la plante ou dans des cellules et plantes et cellules ainsi produites
WO2021028909A1 (fr) 2019-08-12 2021-02-18 Yeda Research And Development Co. Ltd. Test sanguin de réparation de l'adn pour prédire la réponse de patients atteints d'un cancer du poumon à une immunothérapie
WO2021033176A1 (fr) 2019-08-22 2021-02-25 Ariel Scientific Innovations Ltd. Procédés mis à l'échelle de purification d'anticorps
EP4021463A1 (fr) 2019-08-27 2022-07-06 Yeda Research and Development Co. Ltd Traitement de la vaginose bactérienne
WO2021048852A1 (fr) 2019-09-11 2021-03-18 Yeda Research And Development Co. Ltd. Méthodes de traitement du cancer du sein
US20220296622A1 (en) 2019-09-16 2022-09-22 The Children's Hospital Of Philadelphia Compositions and methods for the treatment of swi-snf mutant tumors
US20220331363A1 (en) 2019-09-20 2022-10-20 Shanghai GenBase Biotechnology Co., Ltd. Bcma-targeted antibody and chimeric antigen receptor
IL269674B (en) 2019-09-25 2020-08-31 Roy Bar Ziv Assembling protein complexes on a chip
US20220411511A1 (en) 2019-09-26 2022-12-29 Stcube & Co. Antibodies specific to glycosylated ctla-4 and methods of use thereof
WO2021063201A1 (fr) 2019-09-30 2021-04-08 四川科伦博泰生物医药股份有限公司 Anticorps anti-pd-1 et son utilisation
KR20220088438A (ko) 2019-10-09 2022-06-27 주식회사 에스티큐브앤컴퍼니 글리코실화된 lag3에 대해 특이적인 항체 및 이의 사용 방법
AU2020361455A1 (en) 2019-10-10 2022-04-21 Carlsberg A/S Methods for preparing mutant plants
WO2021080629A1 (fr) 2019-10-23 2021-04-29 Elitechgroup, Inc. Procédés d'amplification par déplacement de brin isotherme véritable
IL270306A (en) 2019-10-30 2021-05-31 Yeda Res & Dev Prevention and treatment of pre-myeloid and myeloid malignancies
EP4051695A1 (fr) 2019-10-31 2022-09-07 Yeda Research and Development Co., Ltd. Bactéries autotrophes génétiquement modifiées pour la conversion de co2 en matériaux organiques
AU2020384953A1 (en) 2019-11-11 2022-06-23 Ibi-Ag Innovative Bio Insecticides Ltd. Insect control nanobodies and uses thereof
IL293148A (en) 2019-11-19 2024-07-01 Protalix Ltd Removal of constructs from transformed cells
IL270800A (en) 2019-11-20 2021-05-31 Yeda Res & Dev A method for treating Alzheimer's disease
US10792360B1 (en) 2019-11-21 2020-10-06 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
IL293489A (en) 2019-12-02 2022-08-01 Caris Mpi Inc predictor of pan-cancer platinum response
EP4073246A4 (fr) 2019-12-12 2023-12-06 President And Fellows Of Harvard College Compositions et méthodes pour le codage à barres biomoléculaire dirigé par la lumière
CA3155759A1 (fr) 2019-12-13 2021-06-17 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Anticorps anti-tslp et utilisations de celui-ci
CN115135671A (zh) 2019-12-20 2022-09-30 新石生物制药有限公司 抗白介素-23 p19的抗体及其使用方法
IL271656A (en) 2019-12-22 2021-06-30 Yeda Res & Dev System and methods for identifying cells that have undergone genome editing
EP4077731A1 (fr) 2019-12-22 2022-10-26 Yeda Research and Development Co. Ltd Diagnostic de la démence frontotemporale
EP3842452A1 (fr) 2019-12-26 2021-06-30 Universitat Autònoma de Barcelona Protéines d'échafaudage et nanoconjugués thérapeutiques à base de nidogène
CN113046421B (zh) 2019-12-26 2022-09-30 厦门大学 一种不对称扩增靶核酸的方法
CN113046420B (zh) 2019-12-26 2022-10-04 厦门大学 一种不对称扩增多个靶核酸的方法
US20230048361A1 (en) 2019-12-31 2023-02-16 Kahr Medical Ltd. Methods of culturing t cells and uses of same
IL271778A (en) 2019-12-31 2021-06-30 Ichilov Tech Ltd Methods for treating atopic dermatitis
WO2021137231A1 (fr) 2019-12-31 2021-07-08 Kahr Medical Ltd. Procédés de culture de lymphocytes t avec un polypeptide de fusion 4-1bbl et leurs utilisations
CN113061165A (zh) 2020-01-02 2021-07-02 厦门大学 EB病毒BNLF2b基因编码多肽及其检测用途
IL272074B2 (en) 2020-01-15 2024-12-01 Immunity Pharma Ltd Peptide compounds and methods of treating diseases using same
IL272194A (en) 2020-01-22 2021-07-29 Yeda Res & Dev Multi-target antibodies for use in the treatment of diseases
WO2021152584A1 (fr) 2020-01-28 2021-08-05 Ariel Scientific Innovations Ltd. Procédés d'analyse de membranes cellulaires
EP4097485A4 (fr) 2020-01-29 2024-05-15 MeMed Diagnostics Ltd. Méthodes de diagnostic et de classification d'infections virales
EP4096647A1 (fr) 2020-01-30 2022-12-07 Yeda Research and Development Co. Ltd Traitement d'une maladie hépatique aiguë à l'aide d'inhibiteurs de tlr-mik
IL272389A (en) 2020-01-30 2021-08-31 Yeda Res & Dev Kits containing antibodies to PD-L1 and their uses in therapy
IL272390A (en) 2020-01-30 2021-08-31 Yeda Res & Dev Cancer treatment methods
WO2021152586A1 (fr) 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Procédés d'analyse du microbiome, du profil d'immunoglobuline et de l'état physiologique
WO2021156490A2 (fr) 2020-02-06 2021-08-12 Vib Vzw Liants du coronavirus
JP2023513334A (ja) 2020-02-09 2023-03-30 エヌエルシー ファーマ リミテッド Ｓａｒｓ－ｃｏｖ－２の迅速検出検査
IL272586A (en) 2020-02-10 2021-08-31 Yeda Res & Dev A method for cell cluster analysis
JP2023519105A (ja) 2020-02-11 2023-05-10 ヴァンダービルト ユニバーシティ 重症急性呼吸器症候群コロナウイルス２（ｓａｒｓ－ｃｏｖ－２）に対するヒトモノクローナル抗体
CA3168337A1 (fr) 2020-02-17 2021-08-26 Marie-Andree Forget Procedes d'expansion de lymphocytes infiltrant les tumeurs et leur utilisation
WO2021170540A1 (fr) 2020-02-25 2021-09-02 Vib Vzw Modulateurs allostériques de la kinase à répétitions riches en leucines 2
EP4110823A1 (fr) 2020-02-26 2023-01-04 A2 Biotherapeutics, Inc. Polypeptides ciblant des complexes mage-a3 peptide-mhc et leurs méthodes d'utilisation
US20230127559A1 (en) 2020-03-16 2023-04-27 Yeda Research And Development Co. Ltd. Peptide analogs and use of same in treating diseases, disorders or conditions associated with mutant p53 protein
US20230150926A1 (en) 2020-03-17 2023-05-18 Genevant Sciences Gmbh Cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells
WO2021195385A1 (fr) 2020-03-26 2021-09-30 Vanderbilt University Anticorps monoclonaux humains dirigés contre le coronavirus du syndrome respiratoire aigu sévère 2 (sras-cov-2)
RS65199B1 (sr) 2020-03-26 2024-03-29 Univ Vanderbilt Humana monoklonska antitela na teški akutni respiratorni sindrom koronavirus 2 (sars-cov-2)
CA3174917A1 (fr) 2020-03-29 2021-10-07 Yeda Research And Development Co. Ltd. Variants de beta-glucocerebrosidase destines a etre utilises dans le traitement de la maladie de gaucher
CN115484944A (zh) 2020-03-31 2022-12-16 坎莫森特里克斯公司 使用ccr9抑制剂和抗il-23阻断抗体治疗炎症性肠病的组合物和方法
AU2021248783A1 (en) 2020-03-31 2022-12-01 Biomuse Ltd. Bacteria for the prevention and treatment of smoke-induced lung damage
EP4133107A1 (fr) 2020-04-06 2023-02-15 Yeda Research and Development Co. Ltd Méthodes de diagnostic du cancer et de prédiction de la réactivité à une thérapie
WO2021205459A1 (fr) 2020-04-07 2021-10-14 Ramot At Tel-Aviv University Ltd. Compositions contenant du cannabidiol et leurs utilisations
US20230135456A1 (en) 2020-04-13 2023-05-04 Exoprother Medical Ltd. Cell-derived vesicles comprising wild-type p53 protein for antiviral therapy
US20210322483A1 (en) 2020-04-16 2021-10-21 Ichilov Tech Ltd. Cell-derived particles presenting heterologous cd24 and use thereof in therapy
BR112022020949A2 (pt) 2020-04-17 2022-12-06 Idexx Lab Inc Imunoensaio de diminuição de fluorescência
WO2021216728A1 (fr) 2020-04-22 2021-10-28 President And Fellows Of Harvard College Procédés isothermes, compositions, kits et systèmes de détection d'acides nucléiques
WO2021229577A1 (fr) 2020-05-12 2021-11-18 Collplant Ltd. Collagène utilisé comme outil d'administration d'agents antiviraux à base de métaux
EP4151235A4 (fr) 2020-05-15 2025-08-06 Sichuan Kelun Biotech Biopharmaceutical Co Ltd Conjugué anticorps-médicament, son procédé de préparation et son utilisation
IL274811B (en) 2020-05-20 2021-05-31 Yeda Res & Dev Spatial information is developed for the analysis of individual cells
IL298934A (en) 2020-06-10 2023-02-01 Univ Ramot Methods for identifying CpGs are implicated
CA3186887A1 (fr) 2020-06-22 2021-12-30 Ramot At Tel-Aviv University Ltd. Modules de proteine a sous-unites multiples, cellules exprimant ceux-ci et leurs utilisations
US20230293530A1 (en) 2020-06-24 2023-09-21 Yeda Research And Development Co. Ltd. Agents for sensitizing solid tumors to treatment
EP3939999A1 (fr) 2020-07-14 2022-01-19 Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Anticorps neutralisant la sous-unité alpha du récepteur de l'interleukine 11 (il11ra) et leurs utilisations
IL276599A (en) 2020-08-09 2022-03-01 Yeda Res & Dev T cell receptor unique to mage-a1 and its uses
IL276627A (en) 2020-08-10 2022-03-01 Yeda Res & Dev Compositions for diagnosis and treatment of coronavirus infections
WO2022038539A2 (fr) 2020-08-18 2022-02-24 Yeda Research And Development Co. Ltd. Composés anti-viraux et anti-tumoraux
WO2022038536A1 (fr) 2020-08-18 2022-02-24 International Rice Research Institute Procédés d'augmentation des taux de croisement de gramineae
WO2022040455A1 (fr) 2020-08-21 2022-02-24 Advanced Cell Diagnostics, Inc. Compositions et procédés pour déterminer une clonalité de lymphocytes t
WO2022047359A1 (fr) 2020-08-31 2022-03-03 Berg Llc Biomarqueurs protéiques du cancer du pancréas
IL277488A (en) 2020-09-21 2022-04-01 Yeda Res & Dev Weight regulation method
IL301503A (en) 2020-09-23 2023-05-01 Yeda res & development co ltd Methods and compositions for treating coronaviral infections
IL277743A (en) 2020-10-01 2022-04-01 Yeda Res & Dev A method for diagnosing breast cancer
US20230374447A1 (en) 2020-10-05 2023-11-23 Protalix Ltd. Dicer-like knock-out plant cells
CA3194643A1 (fr) 2020-10-07 2022-04-14 Ilya Ruderfer Dnase a action prolongee
JP7660671B2 (ja) 2020-10-09 2025-04-11 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 融合前安定化ｈｍｐｖ ｆタンパク質
WO2022079719A1 (fr) 2020-10-15 2022-04-21 Yeda Research And Development Co. Ltd. Méthode de traitement des cancers myéloïdes
IL278401A (en) 2020-10-29 2022-05-01 Yeda Res & Dev Polynucleotides for editing RNA and a method for using them
WO2022097157A2 (fr) 2020-11-09 2022-05-12 1E Therapeutics, Ltd. Méthodes de traitement ou de prévention d'infections bactériennes faisant appel à une séquence catalytique
GB202105804D0 (en) 2020-11-20 2021-06-09 Univ Cape Town Use of microvirin in the identification of mycobacterium tuberculosis mannose-capped lipoarabinomannan
IL302707A (en) 2020-11-26 2023-07-01 Ukko Inc Modified high molecular weight glutenin subunit and uses thereof
US20240101667A1 (en) 2020-12-03 2024-03-28 The Board Of Regents Of The University Of Texas System Methods for identifying lilrb-blocking antibodies
CA3200167A1 (fr) 2020-12-04 2022-06-09 Jonathan S. Wall Procede de diagnostic de maladies amyloides
IL279559A (en) 2020-12-17 2022-07-01 Yeda Res & Dev Controlling ubiquitination of mlkl for treatment of disease
WO2022133344A1 (fr) 2020-12-18 2022-06-23 Genevant Sciences Gmbh Lipides peg et nanoparticules lipidiques
WO2022144882A2 (fr) 2020-12-28 2022-07-07 1E Therapeutics, Ltd. Zones cibles de l'arnm p21 pour le silençage
IL304068A (en) 2020-12-28 2023-08-01 1E Therapeutics Ltd P21 mrna targeting dnazymes
EP4253413A4 (fr) 2020-12-31 2024-11-06 Nona Biosciences (Suzhou) Co., Ltd. Protéine liant un antigène lifr humain, son procédé de préparation et son utilisation
AU2022206415A1 (en) 2021-01-10 2023-08-17 Supermeat The Essence Of Meat Ltd. Pluripotent stem cell aggregates and microtissues obtained therefrom for the cultured meat industry
WO2022153286A1 (fr) 2021-01-14 2022-07-21 Yeda Research And Development Co. Ltd. Procédés de production de vitamine d
IL280340B (en) 2021-01-21 2022-04-01 Yeda Res & Dev Antibodies, peptides and their combinations for the treatment and prevention of corona virus infections
GB2603166A (en) 2021-01-29 2022-08-03 Thelper As Therapeutic and Diagnostic Agents and Uses Thereof
MX2023008895A (es) 2021-02-09 2023-08-09 Medilink Therapeutics Suzhou Co Ltd Conjugado de sustancia bioactiva, metodo de preparacion y uso del mismo.
CA3208536A1 (fr) 2021-02-18 2022-08-25 Ravid STRAUSSMAN Bacteries genetiquement modifiees pour generer des vaccins
EP4294428A1 (fr) 2021-02-18 2023-12-27 Yeda Research and Development Co. Ltd Procédé de génération de vaccins
CA3211270A1 (fr) 2021-02-19 2022-08-25 Vib Vzw Liants de recepteur de mannose-6-phosphate independants des cations
CA3212530A1 (fr) 2021-03-05 2022-09-09 Shanghai GenBase Biotechnology Co., Ltd. Anticorps anti-cldn6 et son utilisation
WO2022192134A1 (fr) 2021-03-08 2022-09-15 Immunogen, Inc. Procédés d'augmentation de l'efficacité d'immunoconjugués ciblant adam9 pour le traitement du cancer
WO2022188652A1 (fr) 2021-03-09 2022-09-15 四川科伦博泰生物医药股份有限公司 Protéine de liaison à ror1 et son utilisation
IL281561A (en) 2021-03-16 2022-10-01 Yeda Res & Dev Methods and devices for ex-utero mouse embryonic development
US20240173369A1 (en) 2021-03-30 2024-05-30 Biomx Ltd. Pseudomonas bacteriophage and uses thereof
CA3214833A1 (fr) 2021-04-06 2022-10-13 Bpgbio, Inc. Marqueurs proteiques pour le pronostic de la progression du cancer du sein
IL307530A (en) 2021-04-06 2023-12-01 Bpgbio Inc Estrogen receptor-like (ER) breast cancer protein markers LUMINAL A (LA) and LUMINAL B1 (LB1)
US20230059578A1 (en) 2021-04-06 2023-02-23 Berg Llc Protein markers for estrogen receptor (er)-positive-like and estrogen receptor (er)-negative-like breast cancer
IL282188A (en) 2021-04-08 2022-11-01 Yeda Res & Dev Combined use of ketamine and bretigabine for the treatment of psychiatric disorders
US20240212150A1 (en) 2021-04-16 2024-06-27 Advanced Cel Diagnostics, Inc. Materials and methods related to image processing
AU2022260794A1 (en) 2021-04-19 2023-11-23 Temple Therapeutics BV Methods for detecting or treating endometrial and ovarian hyperproliferative disorders
AU2022272135A1 (en) 2021-05-12 2024-01-04 Biomx Ltd. Staphylococcus bacteriophage and uses thereof
IL283563A (en) 2021-05-30 2022-12-01 Yeda Res & Dev Profiling of amps for the diagnosis, monitoring and treatment of microbiome-related diseases
CA3219233A1 (fr) 2021-06-06 2022-12-15 Ravid STRAUSSMAN Traitement combine du cancer
AU2022294310A1 (en) 2021-06-13 2024-05-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method for reprogramming human cells
KR20240035997A (ko) 2021-06-16 2024-03-19 시드엑스 테크놀로지스 인코포레이티드 마티올라 종자들을 선별하는 방법들
NL2028466B1 (en) 2021-06-16 2022-12-21 Sakata Holland B V Methods of sorting matthiola seeds
CA3223344A1 (fr) 2021-07-02 2023-01-05 Tropic Biosciences UK Limited Retardement ou prevention du brunissement de bananes
CA3223081A1 (fr) 2021-07-15 2023-01-19 Samir Mitragotri Compositions et methodes associees a des cellules comprenant des particules adherees
IL310226A (en) 2021-07-18 2024-03-01 Gamida Cell Ltd Therapeutic nk cell populations
WO2023002492A1 (fr) 2021-07-22 2023-01-26 Yeda Research And Development Co. Ltd. Optimisation de codon d'acides nucléiques
CA3228014A1 (fr) 2021-07-30 2023-02-16 Vib Vzm Liants du recepteur mannose-6-phosphate independants des cations pour la degradation ciblee de proteines
WO2023012798A2 (fr) 2021-08-02 2023-02-09 Yeda Research And Development Co. Ltd. Anticorps pour le traitement du cancer
CA3226947A1 (fr) 2021-08-03 2023-02-09 Muhammad YASSIN Complexe tcr modifie et ses procedes d'utilisation
EP4130028A1 (fr) 2021-08-03 2023-02-08 Rhazes Therapeutics Ltd Complexe tcr modifié et leurs procédés d'utilisation
JP2024531212A (ja) 2021-08-10 2024-08-29 ガミダ セル リミテッド 改変ｎｋ細胞、その作製方法及びその使用
GB202112865D0 (en) 2021-09-09 2021-10-27 Tropic Biosciences Uk Ltd Resistance to black sigatoka disease in banana
GB202112866D0 (en) 2021-09-09 2021-10-27 Tropic Biosciences Uk Ltd Resistance to fusarium wilt in a banana
IL286430A (en) 2021-09-14 2023-04-01 Yeda Res & Dev Multispecific antibodies for use in the treatment of diseases
WO2023043280A1 (fr) 2021-09-17 2023-03-23 주식회사 씨젠 Détection d'une séquence d'acide nucléique cible à l'aide d'un oligonucléotide marqueur porteur de base non naturelle synthétique
CN117999481A (zh) 2021-10-26 2024-05-07 卡里布生物科学公司 核酸外切酶偶联实时核酸内切酶活性测定
WO2023081070A1 (fr) 2021-11-02 2023-05-11 University Of Massachusetts Protéines de fusion à domaine nme2cas9 incrusté
AU2022392804A1 (en) 2021-11-19 2024-05-02 Mirobio Limited Engineered PD-1 antibodies and uses thereof
US11833503B2 (en) 2021-12-07 2023-12-05 Insilixa, Inc. Methods and compositions for surface functionalization of optical semiconductor-integrated biochips
EP4444864A1 (fr) 2021-12-08 2024-10-16 Yeda Research and Development Co. Ltd Cellules progénitrices pulmonaires multipotentes pour la régénération pulmonaire
WO2023106866A1 (fr) 2021-12-10 2023-06-15 주식회사 씨젠 Amorce à boucle marquée comprenant un système de double marquage interactif simple brin, et procédé d'amplification isotherme d'acide nucléique l'utilisant
JP2025503322A (ja) 2022-01-25 2025-01-30 メディリンク セラピューティクス （スージョウ） カンパニー リミテッド Ｈｅｒ３に対する抗体、複合体、及びその使用
GB202201137D0 (en) 2022-01-28 2022-03-16 Thelper As Therapeutic and diagnostic agents and uses thereof
EP4574172A3 (fr) 2022-01-31 2025-10-01 Genevant Sciences Gmbh Lipides cationiques ionisables pour nanoparticules lipidiques
EP4238988A1 (fr) 2022-03-01 2023-09-06 Consejo Superior De Investigaciones Científicas Anticorps dirigés contre le sars-cov-2 et leurs utilisations
EP4239338A1 (fr) 2022-03-03 2023-09-06 Siemens Healthcare Diagnostics Products GmbH Essai général destiné à la détermination de l'état du système de coagulation sanguine
CN114853890B (zh) 2022-03-16 2023-04-28 沈阳三生制药有限责任公司 一种prlr抗原结合蛋白及其制备方法和应用
KR20240167703A (ko) 2022-04-01 2024-11-27 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 인간 pd-l1 및 pd-l2에 대한 이중 특이성 항체 및 이의 사용 방법
GB202204813D0 (en) 2022-04-01 2022-05-18 Bradcode Ltd Human monoclonal antibodies and methods of use thereof
JP2025511332A (ja) 2022-04-06 2025-04-15 ミロバイオ・リミテッド 操作されたｃｄ２００ｒ抗体及びその使用
KR20240169114A (ko) 2022-04-06 2024-12-02 라리마 테라퓨틱스, 인코포레이티드 프라탁신 대체 요법 모니터링을 위한 프라탁신 민감성 마커
WO2023209708A1 (fr) 2022-04-25 2023-11-02 Yeda Research And Development Co. Ltd. Compositions pour modifier la signalisation de messager secondaire de l'adp-ribose cyclique
CN119744260A (zh) 2022-06-08 2025-04-01 恩库勒公司 作为pi3k抑制剂的苯并嘧啶-4(3h)-酮
WO2023240201A1 (fr) 2022-06-08 2023-12-14 Larimar Therapeutics, Inc. Marqueurs sensibles à la frataxine pour surveiller la progression et le traitement du syndrome de leigh
AU2023283773A1 (en) 2022-06-10 2024-12-19 Research Development Foundation Engineered fcriib selective igg1 fc variants and uses thereof
AU2023286928A1 (en) 2022-06-20 2025-01-02 Sichuan Huiyu Pharmaceutical Co., Ltd. Antibody and use thereof
KR20250034099A (ko) 2022-06-27 2025-03-10 주식회사 씨젠 베타-하이드록시산을 이용한 타겟 핵산의 증폭 방법
TW202404647A (zh) 2022-07-14 2024-02-01 大陸商蘇州宜聯生物醫藥有限公司 抗體藥物偶聯物及其製備方法和用途
WO2024028794A1 (fr) 2022-08-02 2024-02-08 Temple Therapeutics BV Méthodes de traitement de troubles de l'endomètre et de l'hyperprolifération ovarienne
WO2024040020A1 (fr) 2022-08-15 2024-02-22 Absci Corporation Enrichissement de cellule spécifique à une activité d'affinité quantitative
WO2024038160A1 (fr) 2022-08-18 2024-02-22 Vib Vzw Moyens et méthodes pour moduler l'excitabilité neuronale
EP4325224A1 (fr) 2022-08-18 2024-02-21 Siemens Healthcare Diagnostics Products GmbH Essai d'activation plaquettaire destiné au diagnostic d'une thrombocytopénie induite à l'héparine
KR20250080854A (ko) 2022-09-08 2025-06-05 온쿠레 인코포레이티드 Pi3k 억제제로서의 이소퀴놀론
WO2024064024A1 (fr) 2022-09-19 2024-03-28 Onkure, Inc. Dérivés de ((4-oxo-3,4-dihydroquinazolin-8-yl)méthyl)amine utilisés en tant qu'inhibiteurs de p13k pour le traitement du cancer
AU2023344281A1 (en) 2022-09-20 2025-03-13 Onkure, Inc. Hdac inhibitor oki-179 for the treatment of cancers resulting from a mapk pathway mutation
EP4594348A1 (fr) 2022-09-27 2025-08-06 Vib Vzw Antiviraux dirigés contre le virus parainfluenza humain
WO2024081345A1 (fr) 2022-10-14 2024-04-18 Onkure, Inc. Benzopyrimidin-4(3h)-ones utilisées en tant qu'inhibiteurs de pi3k
WO2024080818A1 (fr) 2022-10-14 2024-04-18 주식회사 씨젠 Procédé de détection d'un acide nucléique cible dans un échantillon à l'aide de deux sondes à valeurs tm différentes
KR20250114034A (ko) 2022-11-11 2025-07-28 아이간 바이오사이언스 Iga 프로테아제 폴리펩타이드 제제
KR20250110818A (ko) 2022-11-16 2025-07-21 주식회사 씨젠 퀀칭-pto 절단 및 연장(quenching-pto cleavage and extension；q-ptoce) 어세이에 의한 타겟 핵산의 검출
WO2024124041A1 (fr) 2022-12-07 2024-06-13 Advanced Cell Diagnostics, Inc. Détection multiplexée de cibles d'acides nucléiques
EP4648796A2 (fr) 2023-01-09 2025-11-19 Board of Regents, The University of Texas System Protéines du virus parainfluenza humain 3f stabilisées dans la préfusion
CN120769910A (zh) 2023-02-23 2025-10-10 罗切斯特大学 用于制备封闭端dna线分子的药剂和方法
AU2024252135A1 (en) 2023-04-11 2025-11-27 Sterling Ip Pte. Ltd. Treatment of haematological cancer
TW202504637A (zh) 2023-06-13 2025-02-01 美商艾德森特克斯治療股份有限公司 與結合至nectin-4蛋白之抗體及抗體藥物結合物(adc)相關之方法及組合物
WO2024261344A1 (fr) 2023-06-23 2024-12-26 Vib Vzw Nouveaux liants ciblant le pathogène résistant aux médicaments multiples acinetobacter baumannii
WO2025038395A1 (fr) 2023-08-11 2025-02-20 Onkure, Inc. Benzopyridinones et benzopyrimidinones utilsées en tant qu'inhibiteurs de pi3k
WO2025052278A1 (fr) 2023-09-05 2025-03-13 Genevant Sciences Gmbh Lipides cationiques à base de pyrrolidine pour administration de nanoparticules lipidiques d'agents thérapeutiques à des cellules stellaires hépatiques
WO2025054524A1 (fr) 2023-09-07 2025-03-13 University Of Tennessee Research Foundation Méthode de diagnostic de maladies amyloïdes
WO2025125577A1 (fr) 2023-12-14 2025-06-19 Vib Vzw Anticorps dirigés contre le virus de la grippe b
WO2025133951A1 (fr) 2023-12-21 2025-06-26 Genevant Sciences Gmbh Lipides ionisables appropriés pour des nanoparticules lipidiques
EP4585926A1 (fr) 2024-01-09 2025-07-16 Siemens Healthcare Diagnostics Products GmbH Procédé et kit pour réduire les interférences dans des dosages immunologiques
WO2025150045A1 (fr) 2024-01-12 2025-07-17 Gabriel Nussbaum Cibles bactériennes, agents thérapeutiques, compositions, kits et procédés d'utilisation dans le traitement et/ou la prévention du cancer
WO2025155991A2 (fr) 2024-01-19 2025-07-24 Bpgbio, Inc. Biomarqueurs prédictifs pour la réponse à un traitement par coenzyme q10 dans le cadre d'un cancer du pancréas
WO2025202871A1 (fr) 2024-03-27 2025-10-02 Pfizer Inc. Procédés d'identification de biomarqueurs de réponse à un traitement et leur utilisation avec un inhibiteur de cdk4
WO2025207755A1 (fr) 2024-03-29 2025-10-02 Onkure, Inc. Quinolizinones utilisés en tant qu'inhibiteurs de pi3k
WO2025212360A1 (fr) 2024-04-01 2025-10-09 Onkure, Inc. Isoquinolones en tant qu'inhibiteurs de pi3k

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901654A (en) * 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3935074A (en) * 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies

Also Published As

Publication number Publication date
AU501140B2 (en) 1979-06-14
FR2282115A1 (fr) 1976-03-12
CA1042792A (fr) 1978-11-21
SE426746B (sv) 1983-02-07
SE7509028L (sv) 1976-02-13
GB1526242A (en) 1978-09-27
NL7509587A (nl) 1976-02-16
BR7505107A (pt) 1976-08-31
NL185423C (nl) 1990-04-02
SE7609841L (sv) 1977-03-09
FR2282115B1 (fr) 1981-08-21
JPS6018940B2 (ja) 1985-05-13
US3996345A (en) 1976-12-07
JPS5144628A (fr) 1976-04-16
GB1526241A (en) 1978-09-27
DE2535574C2 (de) 1986-01-16
SE427504B (sv) 1983-04-11
CH621873A5 (fr) 1981-02-27
ES440173A1 (es) 1977-03-01
DE2535574A1 (de) 1976-03-04
IL47835A0 (en) 1975-10-15
AU8388175A (en) 1977-02-17

Similar Documents

Publication Publication Date Title
IL47835A (en) Immunoassay method by fluorescence quenching
EP0399184A3 (fr) Réactifs, procédés et trousses pour un essai immunologique à polarisation de fluorescence d'amphétamines
DE69029016D1 (de) Heterogene Immuntests
AU498364B2 (en) Assaying antibody, antigen or antibody-antigen complex in fluid sample
IE820574L (en) Non-isotopic assay
AU6762087A (en) Method of measuring antigens or antibodies in biological fluids using ligand labelled antigens or ligand labelled antibodies
EP0214847A3 (en) Squarate dye conjugate, process for making it and its use in assay methods and kits
NO175657C (no) Fremgangsmåte for utförelse av en immunologisk bestemmelse av et antigen i en væskepröve samt reagens for bruk til dette
HK11987A (en) Assay
DE3855535D1 (de) Elektrochemilumineszente rhenium-fraktionen und verfahren
NO874140L (no) Immunometriske bestemmelsesfremgangsmaater.
DE3781582D1 (de) Verfahren und reagenz zur bestimmung eines reaktionspartners einer immunologischen reaktion.
KR950006462A (ko) 면역 분석 방법
ATE67599T1 (de) Heterogenes immunoassay.
CA2097952A1 (fr) Diagnostic precoce de la sepsie au moyen des interactions antigene-anticorps amplifiees par chimiluminescence du sang total
ES2081861T3 (es) Inmunoensayo de polarizacion de fluorescencia para la metadona.
ES2076221T3 (es) Derivados geminales de difenilo y su uso en inmunoensayos.
Gomez-Hens Modern aspects of fluorimetry as applied to clinical chemistry
IT1237809B (it) Metodo per la determinazione qualitativa e quantitativa di anticorpi diretti contro antigeni batterici attraverso la misurazione fotometrica dell'agglutinazione.
JPS5712363A (en) Immunoassay for various simultaneous measurement