HUE035999T2 - Citrullinezett 14-3-3 peptidekbõl származó antigének és azok alkalmazásai a reumatoid artritisz diagnózisában - Google Patents

Citrullinezett 14-3-3 peptidekbõl származó antigének és azok alkalmazásai a reumatoid artritisz diagnózisában

Info

Publication number
HUE035999T2
HUE035999T2 HUE12842377A HUE12842377A HUE035999T2 HU E035999 T2 HUE035999 T2 HU E035999T2 HU E12842377 A HUE12842377 A HU E12842377A HU E12842377 A HUE12842377 A HU E12842377A HU E035999 T2 HUE035999 T2 HU E035999T2
Authority
HU
Hungary
Prior art keywords
citrullinated
diagnosis
rheumatoid arthritis
antigens derived
antigens
Prior art date
Application number
HUE12842377A
Other languages
English (en)
Inventor
Anthony Marotta
Original Assignee
Augurex Life Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Augurex Life Sciences Corp filed Critical Augurex Life Sciences Corp
Publication of HUE035999T2 publication Critical patent/HUE035999T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
    • G01N2440/18—Post-translational modifications [PTMs] in chemical analysis of biological material citrullination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/105—Osteoarthritis, e.g. cartilage alteration, hypertrophy of bone

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HUE12842377A 2011-10-21 2012-10-19 Citrullinezett 14-3-3 peptidekbõl származó antigének és azok alkalmazásai a reumatoid artritisz diagnózisában HUE035999T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161550046P 2011-10-21 2011-10-21

Publications (1)

Publication Number Publication Date
HUE035999T2 true HUE035999T2 (hu) 2018-06-28

Family

ID=48140274

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE12842377A HUE035999T2 (hu) 2011-10-21 2012-10-19 Citrullinezett 14-3-3 peptidekbõl származó antigének és azok alkalmazásai a reumatoid artritisz diagnózisában

Country Status (17)

Country Link
US (2) US10132806B2 (hu)
EP (1) EP2768851B1 (hu)
JP (2) JP6844939B2 (hu)
KR (1) KR20140100939A (hu)
CN (1) CN104011068A (hu)
AU (1) AU2012325604B2 (hu)
BR (1) BR112014009536A2 (hu)
CA (1) CA2852758C (hu)
DK (1) DK2768851T3 (hu)
ES (1) ES2638331T3 (hu)
HK (1) HK1201538A1 (hu)
HU (1) HUE035999T2 (hu)
IL (1) IL232169B (hu)
IN (1) IN2014DN03200A (hu)
PL (1) PL2768851T3 (hu)
PT (1) PT2768851T (hu)
WO (1) WO2013056377A1 (hu)

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US10132806B2 (en) * 2011-10-21 2018-11-20 Augurex Life Sciences Corp. Antigens derived from citrullinated 14-3-3 and uses thereof in the diagnosis of rheumatoid arthritis
EP3140323B8 (en) * 2014-05-05 2018-05-23 Novio TH B.V. Method for the serological diagnosis of rheumatoid arthritis.
CN104262489B (zh) * 2014-09-30 2017-01-11 陈仁奋 一种环状瓜氨酸嵌合肽抗原及其应用
KR101758354B1 (ko) 2015-03-26 2017-07-17 한국과학기술연구원 신규한 시클릭 시트룰리네이티드 펩티드, 이를 포함하는 류마티스 관절염 진단용 조성물 및 이를 이용한 진단 방법, 및 류마티스 관절염 마커 스크리닝 방법
WO2017021552A1 (en) * 2015-08-06 2017-02-09 Novimmune Sa Methods and compositions for identifying patient populations for diagnosis and treatment of tlr4-dependent disorders
WO2017139577A1 (en) * 2016-02-10 2017-08-17 Cayman Chemical Company Incorporated Anti-citrullinated hla polypeptide antibodies and uses thereof
CN106644985B (zh) * 2016-12-29 2021-02-05 广州市雷德生物科技有限公司 标志物及其应用、试剂盒、该标志物的检测方法
KR102529594B1 (ko) * 2021-06-23 2023-05-09 재단법인 아산사회복지재단 대동맥판막 협착증 진단 및 예후 예측을 위한 바이오마커로서 항-시트룰린화 펩티드 항체의 용도
CN118240057B (zh) * 2024-05-28 2024-07-23 北京大学人民医院 一种抗原肽及其在制备类风湿关节炎诊断产品中的应用

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Also Published As

Publication number Publication date
US11913950B2 (en) 2024-02-27
EP2768851A1 (en) 2014-08-27
US10132806B2 (en) 2018-11-20
EP2768851A4 (en) 2015-03-11
HK1201538A1 (en) 2015-09-04
AU2012325604B2 (en) 2017-08-03
IL232169B (en) 2018-12-31
US20190310249A1 (en) 2019-10-10
CA2852758A1 (en) 2013-04-25
ES2638331T3 (es) 2017-10-19
PL2768851T3 (pl) 2018-05-30
CA2852758C (en) 2020-12-29
EP2768851B1 (en) 2017-05-31
JP6844939B2 (ja) 2021-03-17
BR112014009536A2 (pt) 2017-04-18
KR20140100939A (ko) 2014-08-18
IL232169A0 (en) 2014-06-30
AU2012325604A1 (en) 2014-06-05
US20140255957A1 (en) 2014-09-11
JP2014530826A (ja) 2014-11-20
PT2768851T (pt) 2017-09-08
WO2013056377A1 (en) 2013-04-25
DK2768851T3 (en) 2017-09-18
JP2019081774A (ja) 2019-05-30
CN104011068A (zh) 2014-08-27
IN2014DN03200A (hu) 2015-05-22

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