MX2021010611A - Aves con genoma editado. - Google Patents
Aves con genoma editado.Info
- Publication number
- MX2021010611A MX2021010611A MX2021010611A MX2021010611A MX2021010611A MX 2021010611 A MX2021010611 A MX 2021010611A MX 2021010611 A MX2021010611 A MX 2021010611A MX 2021010611 A MX2021010611 A MX 2021010611A MX 2021010611 A MX2021010611 A MX 2021010611A
- Authority
- MX
- Mexico
- Prior art keywords
- genome
- birds
- present disclosure
- disclosure provides
- male
- Prior art date
Links
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 210000003837 chick embryo Anatomy 0.000 abstract 1
- 210000002257 embryonic structure Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/30—Bird
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Developmental Biology & Embryology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Environmental Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente descripción proporciona casetes de polinucleótidos exógenos para generar células de aves quiméricas y aves quiméricas. Los casetes de polinucleótidos se pueden utilizar para producir un fenotipo condicionalmente letal en embriones de aves machos. En una modalidad, la presente descripción proporciona métodos para destruir embriones de pollos machos in-ovo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962814162P | 2019-03-05 | 2019-03-05 | |
PCT/IL2020/050242 WO2020178822A1 (en) | 2019-03-05 | 2020-03-03 | Genome-edited birds |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021010611A true MX2021010611A (es) | 2021-11-12 |
Family
ID=70190050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021010611A MX2021010611A (es) | 2019-03-05 | 2020-03-03 | Aves con genoma editado. |
Country Status (13)
Country | Link |
---|---|
US (1) | US20220136003A1 (es) |
EP (1) | EP3934417A1 (es) |
JP (1) | JP2022522848A (es) |
KR (1) | KR20210137499A (es) |
CN (1) | CN113692225B (es) |
AR (1) | AR118239A1 (es) |
AU (1) | AU2020232441A1 (es) |
BR (1) | BR112021017265A2 (es) |
CA (1) | CA3128360A1 (es) |
EA (1) | EA202192430A1 (es) |
IL (1) | IL286011B2 (es) |
MX (1) | MX2021010611A (es) |
WO (1) | WO2020178822A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20200214273A1 (en) * | 2017-09-19 | 2020-07-09 | The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization | Genome-edited birds |
CN110169392B (zh) * | 2019-06-24 | 2021-06-04 | 四川省畜牧科学研究院 | 提高鸡专门化母系繁殖性能的选育方法 |
TW202241259A (zh) * | 2020-12-31 | 2022-11-01 | 以色列國家農業部、農村發展農業研究組織(沃爾卡尼研究所) | 不育禽類胚胎、其產生及用途 |
Family Cites Families (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
NL154599B (nl) | 1970-12-28 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking. |
US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
US3853987A (en) | 1971-09-01 | 1974-12-10 | W Dreyer | Immunological reagent and radioimmuno assay |
US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
NL171930C (nl) | 1972-05-11 | 1983-06-01 | Akzo Nv | Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen. |
US3850578A (en) | 1973-03-12 | 1974-11-26 | H Mcconnell | Process for assaying for biologically active molecules |
US3935074A (en) | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US4034074A (en) | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
US3984533A (en) | 1975-11-13 | 1976-10-05 | General Electric Company | Electrophoretic method of detecting antigen-antibody reaction |
US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
US4879219A (en) | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
US5011771A (en) | 1984-04-12 | 1991-04-30 | The General Hospital Corporation | Multiepitopic immunometric assay |
US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
US5281521A (en) | 1992-07-20 | 1994-01-25 | The Trustees Of The University Of Pennsylvania | Modified avidin-biotin technique |
US5944710A (en) | 1996-06-24 | 1999-08-31 | Genetronics, Inc. | Electroporation-mediated intravascular delivery |
US6774279B2 (en) | 1997-05-30 | 2004-08-10 | Carnegie Institution Of Washington | Use of FLP recombinase in mice |
EP1616943A1 (en) | 1997-08-04 | 2006-01-18 | University of Massachusetts, a Public Institution of Higher Education of The Commonwealth of Massachusetts, | Avian primordial germ cell (PGC) cell line and a method for long term culturing thereof |
CA2325823A1 (en) * | 1998-04-27 | 1999-11-04 | University Health Network | Gene screening methods and related assays |
US20050249735A1 (en) * | 2000-08-07 | 2005-11-10 | Centocor, Inc. | Methods of treating ankylosing spondylitis using anti-TNF antibodies and peptides of human tumor necrosis factor |
WO2002069840A2 (en) * | 2001-03-05 | 2002-09-12 | The State Of Oregon, Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Nucleic acids for transforming fish cells and methods for their use |
US20030232410A1 (en) | 2002-03-21 | 2003-12-18 | Monika Liljedahl | Methods and compositions for using zinc finger endonucleases to enhance homologous recombination |
DE10248361A1 (de) * | 2002-06-30 | 2004-01-22 | Beisswanger, Roland, Dr. | Unterdrückung eines Geschlechtes durch die Veränderung von Geschlechtschromosomen |
JP2006502748A (ja) | 2002-09-05 | 2006-01-26 | カリフォルニア インスティテュート オブ テクノロジー | 遺伝子ターゲッティングを誘発するキメラヌクレアーゼの使用方法 |
CN1761756B (zh) | 2003-01-16 | 2013-03-13 | 北卡罗来纳州大学 | 禽类物种中内源性原生殖细胞的耗减 |
US20060014264A1 (en) | 2004-07-13 | 2006-01-19 | Stowers Institute For Medical Research | Cre/lox system with lox sites having an extended spacer region |
US20060174362A1 (en) * | 2005-02-01 | 2006-08-03 | Origen Therapeutics, Inc. | Long-term culture of avian primordial germ cells (PGCs) |
US8088976B2 (en) * | 2005-02-24 | 2012-01-03 | Monsanto Technology Llc | Methods for genetic control of plant pest infestation and compositions thereof |
DK2650365T3 (en) | 2005-10-18 | 2016-12-05 | Prec Biosciences | RATIONAL MEGANUCLEASES constructed with altered sequence specificity and DNA binding affinity |
EP3159414A1 (en) * | 2006-02-10 | 2017-04-26 | Oxitec Limited | Expression system |
KR101563017B1 (ko) * | 2007-08-14 | 2015-10-23 | 오리겐 테라퓨틱스 인코포레이티드 | 불활성화된 내인성 유전자좌를 갖는 트랜스제닉 닭 |
US7732659B2 (en) * | 2007-11-20 | 2010-06-08 | Genetic Services, Inc. | Injecting Drosophila embryos |
EP2067402A1 (en) | 2007-12-07 | 2009-06-10 | Max Delbrück Centrum für Molekulare Medizin (MDC) Berlin-Buch; | Transponson-mediated mutagenesis in spermatogonial stem cells |
WO2009126250A2 (en) * | 2008-04-07 | 2009-10-15 | Nupotential, Inc. | Reprogramming a cell by inducing a pluripotent gene through rna interference |
CN102858985A (zh) * | 2009-07-24 | 2013-01-02 | 西格马-奥尔德里奇有限责任公司 | 基因组编辑方法 |
US20120192298A1 (en) * | 2009-07-24 | 2012-07-26 | Sigma Aldrich Co. Llc | Method for genome editing |
CN102695798A (zh) * | 2009-11-23 | 2012-09-26 | 水慷科技公司 | 母系诱导的动物不育 |
CN103025344B (zh) | 2010-05-17 | 2016-06-29 | 桑格摩生物科学股份有限公司 | 新型dna-结合蛋白及其用途 |
GB201112429D0 (en) * | 2011-07-19 | 2011-08-31 | Glaxo Group Ltd | Antigen-binding proteins with increased FcRn binding |
GB2500113A (en) * | 2012-03-05 | 2013-09-11 | Oxitec Ltd | Arthropod male germline gene expression system |
AU2013293270B2 (en) | 2012-07-25 | 2018-08-16 | Massachusetts Institute Of Technology | Inducible DNA binding proteins and genome perturbation tools and applications thereof |
JP6279574B2 (ja) * | 2012-07-30 | 2018-02-14 | イン オーヴォ ベスローデン フエンノートシャップ | 卵内の鳥類胚の性別、生存能および/または発生段階の決定 |
WO2014085593A1 (en) | 2012-11-27 | 2014-06-05 | Children's Medical Center Corporation | Targeting bcl11a distal regulatory elements for fetal hemoglobin reinduction |
US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
JP6497605B2 (ja) * | 2014-11-14 | 2019-04-10 | 国立研究開発法人農業・食品産業技術総合研究機構 | 雌蚕致死カイコ系統 |
EP3078675A1 (en) * | 2015-04-10 | 2016-10-12 | Ares Trading S.A. | Induction dosing regimen for the treatment of tnf alpha mediated disorders |
CN105524941A (zh) * | 2016-01-19 | 2016-04-27 | 扬州大学 | 一种特异于禽类原始生殖细胞的基因转移系统及方法 |
WO2018013759A1 (en) * | 2016-07-13 | 2018-01-18 | Yorktown Technologies, L.P. | Poultry and offspring sex selection |
US20180320164A1 (en) * | 2017-05-05 | 2018-11-08 | California Institute Of Technology | Dna sequence modification-based gene drive |
US20200214273A1 (en) * | 2017-09-19 | 2020-07-09 | The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization | Genome-edited birds |
-
2020
- 2020-03-03 CN CN202080024808.7A patent/CN113692225B/zh active Active
- 2020-03-03 MX MX2021010611A patent/MX2021010611A/es unknown
- 2020-03-03 AU AU2020232441A patent/AU2020232441A1/en active Pending
- 2020-03-03 EP EP20717323.8A patent/EP3934417A1/en active Pending
- 2020-03-03 JP JP2021552184A patent/JP2022522848A/ja active Pending
- 2020-03-03 KR KR1020217031931A patent/KR20210137499A/ko unknown
- 2020-03-03 WO PCT/IL2020/050242 patent/WO2020178822A1/en active Application Filing
- 2020-03-03 CA CA3128360A patent/CA3128360A1/en active Pending
- 2020-03-03 EA EA202192430A patent/EA202192430A1/ru unknown
- 2020-03-03 IL IL286011A patent/IL286011B2/en unknown
- 2020-03-03 US US17/435,485 patent/US20220136003A1/en active Pending
- 2020-03-03 BR BR112021017265A patent/BR112021017265A2/pt unknown
- 2020-03-04 AR ARP200100587A patent/AR118239A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
BR112021017265A2 (pt) | 2021-12-21 |
CN113692225A (zh) | 2021-11-23 |
CA3128360A1 (en) | 2020-09-10 |
EP3934417A1 (en) | 2022-01-12 |
AU2020232441A1 (en) | 2021-09-23 |
EA202192430A1 (ru) | 2022-02-11 |
IL286011B1 (en) | 2024-02-01 |
IL286011A (en) | 2021-10-31 |
US20220136003A1 (en) | 2022-05-05 |
JP2022522848A (ja) | 2022-04-20 |
CN113692225B (zh) | 2023-04-18 |
WO2020178822A1 (en) | 2020-09-10 |
KR20210137499A (ko) | 2021-11-17 |
AR118239A1 (es) | 2021-09-22 |
IL286011B2 (en) | 2024-06-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2021010611A (es) | Aves con genoma editado. | |
MX2019012311A (es) | Metodos y composiciones para modificaciones geneticas dirigidas y metodos de uso. | |
CO2019011450A2 (es) | Expresión transgénica selectiva de tejidos | |
SA517380984B1 (ar) | طريقة لإنتاج خلايا سليفة في كبد بالغ | |
MX2020004541A (es) | Edicion de genes de celulas primarias. | |
AR101080A1 (es) | Transformación de maíz haploide con una nucleasa específica de sitio | |
NZ738689A (en) | Engineered crispr-cas9 compositions and methods of use | |
MX2017004890A (es) | Metodos y composiciones para la generación o el mantenimiento de células pluripotentes. | |
GB2562396A (en) | Devices for simulating a function of a liver tissue and methods of use and manufacturing thereof | |
MX2016016903A (es) | Animales no humanos que tienen un gen de muerte celular programada 1 humanizado. | |
BR112017018885A2 (pt) | método de cultura celular para células-tronco mesenquimais | |
WO2017048809A8 (en) | Nk cells exhibiting an adaptive phenotype and methods for preparing and for using | |
ZA202004679B (en) | Regeneration of genetically modified plants | |
NZ728159A (en) | Nanos2 knock-out that ablates germline cells | |
SG11202104775SA (en) | Animal Cell Growth Promoter, Medium For Culturing Animal Cells, And Device For Culturing Animal Cells | |
MX2021007433A (es) | Metodos de cultivo de una celula de mamifero. | |
MX2020003954A (es) | Vectores lentivirales para suministro de pklr para el tratamiento de deficiencia de piruvato quinasa. | |
IL279172A (en) | Methods for the production of hematopoietic stem cells | |
BR112017013487A2 (pt) | sistema para cultura de células em um ambiente controlado | |
MX2016010284A (es) | Uso de acido guanidinoacetico y/o creatina para incrementar la proporcion de eclosion. | |
WO2015171852A3 (en) | Methods and compositions for non-cytotoxic stem cell transplantation | |
MX2020003123A (es) | Aves con genoma editado. | |
PH12018500117A1 (en) | Methods and compositions using bifidobacterium longum to optimize breastfeeding | |
WO2018144087A3 (en) | Dna plasmids for the fast generation of homologous recombination vectors for cell line development | |
SG10201912931RA (en) | Pluripotent stem cell manufacturing system, method for inducing stem cells, floating culture method for stem cells, floating culture vessel for stem cells, method for producing induced pluripotent stem cells, and method for producing particular somatic cells from animal cells |