PL2757091T3 - Stabilizowane ciemne wygaszające sondy fluoroforowe kwasu nukleinowego - Google Patents

Stabilizowane ciemne wygaszające sondy fluoroforowe kwasu nukleinowego

Info

Publication number
PL2757091T3
PL2757091T3 PL14152335T PL14152335T PL2757091T3 PL 2757091 T3 PL2757091 T3 PL 2757091T3 PL 14152335 T PL14152335 T PL 14152335T PL 14152335 T PL14152335 T PL 14152335T PL 2757091 T3 PL2757091 T3 PL 2757091T3
Authority
PL
Poland
Prior art keywords
nucleic acid
dark quencher
stabilized nucleic
fluorophore probes
acid dark
Prior art date
Application number
PL14152335T
Other languages
English (en)
Inventor
Ronald M Cook
Matt Lyttle
Original Assignee
Biosearch Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosearch Tech Inc filed Critical Biosearch Tech Inc
Publication of PL2757091T3 publication Critical patent/PL2757091T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B31/00—Disazo and polyazo dyes of the type A->B->C, A->B->C->D, or the like, prepared by diazotising and coupling
    • C09B31/02—Disazo dyes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
PL14152335T 2008-04-01 2009-04-01 Stabilizowane ciemne wygaszające sondy fluoroforowe kwasu nukleinowego PL2757091T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4151508P 2008-04-01 2008-04-01
EP14152335.7A EP2757091B1 (en) 2008-04-01 2009-04-01 Stabilized Nucleic Acid Dark Quencher-Fluorophore Probes
EP09726629A EP2268608A4 (en) 2008-04-01 2009-04-01 DARK NUCLEIC ACID STABILIZED FLUOROPHORE DEACTIVATOR PROBES

Publications (1)

Publication Number Publication Date
PL2757091T3 true PL2757091T3 (pl) 2017-10-31

Family

ID=41136104

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14152335T PL2757091T3 (pl) 2008-04-01 2009-04-01 Stabilizowane ciemne wygaszające sondy fluoroforowe kwasu nukleinowego

Country Status (15)

Country Link
US (3) US8466266B2 (pl)
EP (2) EP2268608A4 (pl)
JP (1) JP5669721B2 (pl)
CN (1) CN102037144B (pl)
CA (1) CA2720511A1 (pl)
CY (1) CY1119237T1 (pl)
DK (1) DK2757091T3 (pl)
ES (1) ES2633786T3 (pl)
HR (1) HRP20171087T1 (pl)
LT (1) LT2757091T (pl)
MX (1) MX2010010881A (pl)
PL (1) PL2757091T3 (pl)
PT (1) PT2757091T (pl)
SI (1) SI2757091T1 (pl)
WO (1) WO2009124150A2 (pl)

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PL2757091T3 (pl) 2008-04-01 2017-10-31 Biosearch Tech Inc Stabilizowane ciemne wygaszające sondy fluoroforowe kwasu nukleinowego
EP2553123B1 (en) * 2010-03-26 2016-08-24 Integrated DNA Technologies, Inc. Methods for enhancing nucleic acid hybridization
US9506057B2 (en) 2010-03-26 2016-11-29 Integrated Dna Technologies, Inc. Modifications for antisense compounds
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KR102360517B1 (ko) * 2014-05-09 2022-02-09 바이오서치 테크날로지즈, 인크. 코스믹 소광제
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KR102237237B1 (ko) * 2017-11-28 2021-04-07 에스에프씨 주식회사 소광자 및 이의 용도
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JP2023515053A (ja) * 2020-02-24 2023-04-12 インテグレーティッド ディーエヌエイ テクノロジーズ インコーポレーティッド 固体支持体上でのオリゴヌクレオチド合成
WO2021240443A1 (en) 2020-05-27 2021-12-02 King Abdullah University Of Science And Technology Iscan: an rt-lamp-coupled crispr-cas module for rapid, sensitive detection of sars-cov-2
CN111647073B (zh) * 2020-07-03 2022-10-18 广东工业大学 一种荧光探针及其制备方法
CN112500714B (zh) * 2020-09-25 2021-10-22 四川大学 基于磷原子取代罗丹明衍生物骨架的染色试剂及其制备方法和应用
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CN114295594B (zh) * 2021-12-06 2023-09-19 贵州理工学院 一种基于分子信标筛选三螺旋DNA嵌入剂的“turn on”型荧光传感器
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Also Published As

Publication number Publication date
MX2010010881A (es) 2011-03-04
CA2720511A1 (en) 2009-10-08
PT2757091T (pt) 2017-07-24
US20110282041A1 (en) 2011-11-17
WO2009124150A2 (en) 2009-10-08
EP2268608A4 (en) 2012-01-11
DK2757091T3 (en) 2017-08-14
EP2268608A2 (en) 2011-01-05
CN102037144B (zh) 2013-09-25
CN102037144A (zh) 2011-04-27
JP2011519356A (ja) 2011-07-07
HRP20171087T1 (hr) 2017-10-06
JP5669721B2 (ja) 2015-02-12
EP2757091A1 (en) 2014-07-23
EP2757091B1 (en) 2017-06-28
ES2633786T3 (es) 2017-09-25
CY1119237T1 (el) 2018-02-14
WO2009124150A3 (en) 2009-12-30
US9803240B2 (en) 2017-10-31
US8674094B2 (en) 2014-03-18
US20090259030A1 (en) 2009-10-15
US8466266B2 (en) 2013-06-18
LT2757091T (lt) 2017-09-11
US20140194611A1 (en) 2014-07-10
SI2757091T1 (en) 2018-01-31

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