MX2021010559A - Polipéptidos efectores de crispr-cas y métodos de uso de estos. - Google Patents

Polipéptidos efectores de crispr-cas y métodos de uso de estos.

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Publication number
MX2021010559A
MX2021010559A MX2021010559A MX2021010559A MX2021010559A MX 2021010559 A MX2021010559 A MX 2021010559A MX 2021010559 A MX2021010559 A MX 2021010559A MX 2021010559 A MX2021010559 A MX 2021010559A MX 2021010559 A MX2021010559 A MX 2021010559A
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Mexico
Prior art keywords
present disclosure
cas effector
rna
crispr
disclosure provides
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MX2021010559A
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English (en)
Inventor
Jennifer A Doudna
Jillian F Banfield
Basem Al-Shayeb
Patrick Pausch
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Univ California
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Publication of MX2021010559A publication Critical patent/MX2021010559A/es

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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

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Abstract

La presente descripción proporciona proteínas efectoras CRISPR-Cas guiadas por ARN, ácidos nucleicos que las codifican y composiciones que las comprenden. La presente descripción proporciona complejos de ribonucleoproteína que comprende: una proteína efectora CRISPR-Cas guiada por ARN de la presente descripción; y un ARN guía. La presente descripción proporciona métodos para modificar un ácido nucleico objetivo mediante el uso de una proteína efectora CRISPR-Cas guiada por ARN de la presente descripción; y un ARN guía. La presente descripción proporciona métodos para modular la transcripción de un ácido nucleico objetivo.
MX2021010559A 2019-03-07 2020-03-05 Polipéptidos efectores de crispr-cas y métodos de uso de estos. MX2021010559A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962815173P 2019-03-07 2019-03-07
US201962855739P 2019-05-31 2019-05-31
US201962907422P 2019-09-27 2019-09-27
US201962948470P 2019-12-16 2019-12-16
PCT/US2020/021213 WO2020181101A1 (en) 2019-03-07 2020-03-05 Crispr-cas effector polypeptides and methods of use thereof

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Publication Number Publication Date
MX2021010559A true MX2021010559A (es) 2021-12-15

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MX2021010559A MX2021010559A (es) 2019-03-07 2020-03-05 Polipéptidos efectores de crispr-cas y métodos de uso de estos.
MX2023003255A MX2023003255A (es) 2019-03-07 2021-09-02 Polipeptidos efectores crispr-cas y metodos para su uso.

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US (13) US20210324356A1 (es)
EP (2) EP4219700A1 (es)
JP (2) JP7239725B2 (es)
CN (2) CN113811607A (es)
AU (2) AU2020231380A1 (es)
CA (1) CA3130789A1 (es)
DE (1) DE212020000516U1 (es)
GB (1) GB2595606B (es)
MX (2) MX2021010559A (es)
WO (1) WO2020181101A1 (es)

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