EP2313527A4 - Lateral flow nucleic acid detector - Google Patents

Lateral flow nucleic acid detector

Info

Publication number
EP2313527A4
EP2313527A4 EP09798690A EP09798690A EP2313527A4 EP 2313527 A4 EP2313527 A4 EP 2313527A4 EP 09798690 A EP09798690 A EP 09798690A EP 09798690 A EP09798690 A EP 09798690A EP 2313527 A4 EP2313527 A4 EP 2313527A4
Authority
EP
European Patent Office
Prior art keywords
nucleic acid
lateral flow
acid detector
flow nucleic
detector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP09798690A
Other languages
German (de)
French (fr)
Other versions
EP2313527A2 (en
Inventor
Robert P Sambursky
Uma Mahesh Babu
Robert W Vandine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rapid Pathogen Screening Inc
Original Assignee
Rapid Pathogen Screening Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/502,626 external-priority patent/US8669052B2/en
Priority claimed from US12/502,662 external-priority patent/US8614101B2/en
Application filed by Rapid Pathogen Screening Inc filed Critical Rapid Pathogen Screening Inc
Publication of EP2313527A2 publication Critical patent/EP2313527A2/en
Publication of EP2313527A4 publication Critical patent/EP2313527A4/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
EP09798690A 2008-07-15 2009-07-15 Lateral flow nucleic acid detector Ceased EP2313527A4 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US8087908P 2008-07-15 2008-07-15
US9893508P 2008-09-22 2008-09-22
US17905909P 2009-05-18 2009-05-18
US12/502,626 US8669052B2 (en) 2008-06-10 2009-07-14 Lateral flow nucleic acid detector
US12/502,662 US8614101B2 (en) 2008-05-20 2009-07-14 In situ lysis of cells in lateral flow immunoassays
PCT/US2009/050645 WO2010009203A2 (en) 2008-07-15 2009-07-15 Lateral flow nucleic acid detector

Publications (2)

Publication Number Publication Date
EP2313527A2 EP2313527A2 (en) 2011-04-27
EP2313527A4 true EP2313527A4 (en) 2012-11-21

Family

ID=41550997

Family Applications (2)

Application Number Title Priority Date Filing Date
EP09798691A Withdrawn EP2313775A4 (en) 2008-07-15 2009-07-15 In situ lysis of cells in lateral flow immunoassays
EP09798690A Ceased EP2313527A4 (en) 2008-07-15 2009-07-15 Lateral flow nucleic acid detector

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP09798691A Withdrawn EP2313775A4 (en) 2008-07-15 2009-07-15 In situ lysis of cells in lateral flow immunoassays

Country Status (3)

Country Link
EP (2) EP2313775A4 (en)
JP (2) JP2012503170A (en)
WO (2) WO2010009203A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102236022B (en) * 2010-04-26 2015-04-22 艾博生物医药(杭州)有限公司 Detection device
MX340094B (en) 2010-11-02 2016-06-27 Kypha Inc Lateral flow immunoassay for complement activation and methods of use for point-of-care assessment of complement-associated disorders.
EP2734647B1 (en) * 2011-07-22 2018-10-17 Access Bio, Inc. A single-pad strip for an improved lateral flow assay and a test device using the same
US20150004624A1 (en) * 2012-01-16 2015-01-01 Koninklijke Philips N.V. Determining a presence of target molecules in a body fluid comprising cells
JP2013198482A (en) * 2012-02-22 2013-10-03 Nippon Meat Packers Inc Detection method of nucleic acid
KR101409263B1 (en) * 2012-10-16 2014-07-02 바디텍메드 주식회사 Strip with subpad for lateral flow analysis and cartridge for the same
CN104471398B (en) * 2012-11-28 2016-10-26 古河电气工业株式会社 The detection device used in immunochromatographic method, the method
CA2897495C (en) * 2013-03-07 2021-07-13 Rapid Pathogen Screening, Inc. Multiplanar lateral flow assay with diverting zone
JP6177009B2 (en) * 2013-06-03 2017-08-09 株式会社日立ハイテクノロジーズ Blood cell destruction reagent and blood cell destruction method using the same
EP3063317B1 (en) * 2013-10-28 2020-06-03 DOTS Technology Corp. Allergen detection
CA2941248A1 (en) * 2014-03-12 2015-09-17 Mc10, Inc. Quantification of a change in assay
US10808287B2 (en) 2015-10-23 2020-10-20 Rapid Pathogen Screening, Inc. Methods and devices for accurate diagnosis of infections
CN107478829A (en) * 2017-09-29 2017-12-15 亳州市新健康科技有限公司 A kind of illicit drugs inspection kit and its preparation technology based on double competition immunochromatographic methods

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994016108A1 (en) * 1993-01-15 1994-07-21 The Public Health Research Institute Of The City Of New York, Inc. Sensitive nucleic acid sandwich hybridization assays and kits
WO2000029112A1 (en) * 1998-11-18 2000-05-25 Orchid Biosciences, Inc. One-step nucleic acid dipstick device with movable membrane
WO2002004122A2 (en) * 2000-07-07 2002-01-17 Helen Lee Improved stability of hybridisation interactions in dipstick assays
WO2004007078A1 (en) * 2002-07-12 2004-01-22 British Biocell International Limited Lateral flow assay device and method
US20040072176A1 (en) * 2000-07-07 2004-04-15 Helen Lee Binding interactions in dipstick assays

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
WO1997023781A1 (en) * 1995-12-22 1997-07-03 Universal Healthwatch, Inc. Fecal test method and device
US6358752B1 (en) * 1996-09-27 2002-03-19 Cornell Research Foundation, Inc. Liposome-enhanced test device and method
DE19816550A1 (en) * 1997-12-24 1999-06-24 Roche Diagnostics Gmbh Universally applicable structure of an analysis element and its use for analyte determination
EP1192466B1 (en) * 1999-06-23 2004-08-11 Cornell Research Foundation, Inc. Dehydration/rehydration of marked liposomes on a test device
SE0103072D0 (en) * 2001-09-17 2001-09-17 Pharmacia Diagnostics Ab Multi-analyte assay device with multi-spot detection zone
US20040241779A1 (en) * 2003-02-24 2004-12-02 Piasio Roger N. Dry chemistry, lateral flow-reconstituted chromatographic enzyme-driven assays
ATE504660T1 (en) * 2003-05-07 2011-04-15 Coris Bioconcept Sprl SINGLE STAGE OLIGOCHROMATOGRAPHIC APPARATUS AND METHOD FOR USE THEREOF
JP2005017248A (en) * 2003-06-30 2005-01-20 Asahi Breweries Ltd Analysis device for immunochromatography
US20060019406A1 (en) * 2004-07-23 2006-01-26 Ning Wei Lateral flow device for the detection of large pathogens
EP1657550A1 (en) * 2004-11-10 2006-05-17 Coris Bioconcept SPRL Double-sided device for multiplex dipstick immunodiagnostic
NL1027737C2 (en) * 2004-12-14 2006-06-16 Teststrip B V Chromatographic analysis device and test kit.
US20060240569A1 (en) * 2005-04-20 2006-10-26 Becton, Dickinson And Company Semi-quantitative immunochromatographic device
US7618810B2 (en) * 2005-12-14 2009-11-17 Kimberly-Clark Worldwide, Inc. Metering strip and method for lateral flow assay devices
US8007999B2 (en) * 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994016108A1 (en) * 1993-01-15 1994-07-21 The Public Health Research Institute Of The City Of New York, Inc. Sensitive nucleic acid sandwich hybridization assays and kits
WO2000029112A1 (en) * 1998-11-18 2000-05-25 Orchid Biosciences, Inc. One-step nucleic acid dipstick device with movable membrane
WO2002004122A2 (en) * 2000-07-07 2002-01-17 Helen Lee Improved stability of hybridisation interactions in dipstick assays
US20040072176A1 (en) * 2000-07-07 2004-04-15 Helen Lee Binding interactions in dipstick assays
WO2004007078A1 (en) * 2002-07-12 2004-01-22 British Biocell International Limited Lateral flow assay device and method

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
D. J. CARTER ET AL: "Lateral flow microarrays: a novel platform for rapid nucleic acid detection based on miniaturized lateral flow chromatography", NUCLEIC ACIDS RESEARCH, vol. 35, no. 10, 22 April 2007 (2007-04-22), pages e74 - e74, XP055008543, ISSN: 0305-1048, DOI: 10.1093/nar/gkm269 *
DINEVA MAGDA ANASTASSOVA ET AL: "Simultaneous visual detection of multiple viral amplicons by dipstick assay", JOURNAL OF CLINICAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, DC, US, vol. 43, no. 8, 1 August 2005 (2005-08-01), pages 4015 - 4021, XP002449306, ISSN: 0095-1137, DOI: 10.1128/JCM.43.8.4015-4021.2005 *
R. BLAKE ET AL: "Thermodynamic effects of formamide on DNA stability", NUCLEIC ACIDS RESEARCH, vol. 24, no. 11, 1 June 1996 (1996-06-01), pages 2095 - 2103, XP055245590, DOI: 10.1093/nar/24.11.2095 *
RULE GEOFFREY S ET AL: "Rapid method for visual identification of specific DNA sequences based on DNA-tagged liposomes", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, vol. 42, no. 8 PART 1, 1 January 1996 (1996-01-01), pages 1206 - 1209, XP002559997, ISSN: 0009-9147 *

Also Published As

Publication number Publication date
WO2010009206A3 (en) 2010-05-14
WO2010009203A3 (en) 2010-04-08
WO2010009203A2 (en) 2010-01-21
WO2010009206A2 (en) 2010-01-21
JP2011528229A (en) 2011-11-17
JP2012503170A (en) 2012-02-02
EP2313775A2 (en) 2011-04-27
EP2313775A4 (en) 2012-03-14
EP2313527A2 (en) 2011-04-27
JP5948056B2 (en) 2016-07-06

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