JP6144355B2 - 化学修飾ｍＲＮＡ - Google Patents

化学修飾ｍＲＮＡ Download PDF

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Publication number
JP6144355B2
JP6144355B2 JP2015544065A JP2015544065A JP6144355B2 JP 6144355 B2 JP6144355 B2 JP 6144355B2 JP 2015544065 A JP2015544065 A JP 2015544065A JP 2015544065 A JP2015544065 A JP 2015544065A JP 6144355 B2 JP6144355 B2 JP 6144355B2
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mir
mrna
modified
utr
sequence
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Japanese (ja)
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JP2015535430A (ja
Inventor
チャクラボルティ、ティルタ
バンセル、ステファヌ
ジー． ホーグ、スティーブン
ジー． ホーグ、スティーブン
ロイ、アタヌ
フジェローレ、アントニン ドゥ
フジェローレ、アントニン ドゥ
ビー． アフェヤン、ヌバール
ビー． アフェヤン、ヌバール
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ModernaTx Inc
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ModernaTx Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49447811&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP6144355(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
JP2015544065A 2012-11-26 2013-10-02 化学修飾ｍＲＮＡ Active JP6144355B2 (ja)

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US201261729933P 2012-11-26 2012-11-26
US61/729,933 2012-11-26
US201261737224P 2012-12-14 2012-12-14
US61/737,224 2012-12-14
US201361758921P 2013-01-31 2013-01-31
US61/758,921 2013-01-31
US201361775509P 2013-03-09 2013-03-09
US61/775,509 2013-03-09
US201361781139P 2013-03-14 2013-03-14
US61/781,139 2013-03-14
US201361829372P 2013-05-31 2013-05-31
US201361829359P 2013-05-31 2013-05-31
US61/829,359 2013-05-31
US61/829,372 2013-05-31
US201361839903P 2013-06-27 2013-06-27
US61/839,903 2013-06-27
US201361842709P 2013-07-03 2013-07-03
US61/842,709 2013-07-03
US201361857436P 2013-07-23 2013-07-23
US61/857,436 2013-07-23
PCT/US2013/062943 WO2014081507A1 (en) 2012-11-26 2013-10-02 Terminally modified rna

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017093692A Division JP6377804B2 (ja) 2012-11-26 2017-05-10 末端修飾ｒｎａ

Publications (2)

Publication Number Publication Date
JP2015535430A JP2015535430A (ja) 2015-12-14
JP6144355B2 true JP6144355B2 (ja) 2017-06-07

Family

ID=49447811

Family Applications (5)

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JP2015544065A Active JP6144355B2 (ja) 2012-11-26 2013-10-02 化学修飾ｍＲＮＡ
JP2017093692A Active JP6377804B2 (ja) 2012-11-26 2017-05-10 末端修飾ｒｎａ
JP2018138949A Active JP6666391B2 (ja) 2012-11-26 2018-07-25 化学修飾ｍＲＮＡ
JP2020026728A Active JP7047002B2 (ja) 2012-11-26 2020-02-20 化学修飾ｍＲＮＡ
JP2022046812A Pending JP2022093332A (ja) 2012-11-26 2022-03-23 化学修飾ｍＲＮＡ

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2017093692A Active JP6377804B2 (ja) 2012-11-26 2017-05-10 末端修飾ｒｎａ
JP2018138949A Active JP6666391B2 (ja) 2012-11-26 2018-07-25 化学修飾ｍＲＮＡ
JP2020026728A Active JP7047002B2 (ja) 2012-11-26 2020-02-20 化学修飾ｍＲＮＡ
JP2022046812A Pending JP2022093332A (ja) 2012-11-26 2022-03-23 化学修飾ｍＲＮＡ

Country Status (16)

Country Link
US (5) US9597380B2 (enExample)
EP (2) EP4074834A1 (enExample)
JP (5) JP6144355B2 (enExample)
AU (3) AU2017202228B2 (enExample)
CA (1) CA2892529C (enExample)
CY (1) CY1125236T1 (enExample)
DK (1) DK2922554T3 (enExample)
ES (1) ES2921623T3 (enExample)
HR (1) HRP20220607T1 (enExample)
LT (1) LT2922554T (enExample)
PL (1) PL2922554T3 (enExample)
PT (1) PT2922554T (enExample)
RS (1) RS63237B1 (enExample)
SI (1) SI2922554T1 (enExample)
SM (1) SMT202200337T1 (enExample)
WO (1) WO2014081507A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3312494B2 (ja) 1994-08-31 2002-08-05 富士ゼロックス株式会社 データ処理装置

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