FI973559A - Menetelmiä ja koostumuksia heterologisten polypeptidien erittämiseksi - Google Patents

Menetelmiä ja koostumuksia heterologisten polypeptidien erittämiseksi Download PDF

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Publication number
FI973559A
FI973559A FI973559A FI973559A FI973559A FI 973559 A FI973559 A FI 973559A FI 973559 A FI973559 A FI 973559A FI 973559 A FI973559 A FI 973559A FI 973559 A FI973559 A FI 973559A
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FI
Finland
Prior art keywords
compositions
polypeptide
methods
interest
heterologous polypeptides
Prior art date
Application number
FI973559A
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English (en)
Swedish (sv)
Other versions
FI120357B (fi
FI973559A0 (fi
Inventor
Laura C Simmons
Daniel G Yansura
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of FI973559A0 publication Critical patent/FI973559A0/fi
Publication of FI973559A publication Critical patent/FI973559A/fi
Application granted granted Critical
Publication of FI120357B publication Critical patent/FI120357B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Electrotherapy Devices (AREA)
  • External Artificial Organs (AREA)
FI973559A 1995-03-01 1997-08-29 Menetelmiä ja koostumuksia heterologisten polypeptidien erittämiseksi FI120357B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39861595 1995-03-01
US08/398,615 US5840523A (en) 1995-03-01 1995-03-01 Methods and compositions for secretion of heterologous polypeptides
US9602858 1996-02-27
PCT/US1996/002858 WO1996027016A1 (en) 1995-03-01 1996-02-27 Methods and compositions for secretion of heterologous polypeptides

Publications (3)

Publication Number Publication Date
FI973559A0 FI973559A0 (fi) 1997-08-29
FI973559A true FI973559A (fi) 1997-10-29
FI120357B FI120357B (fi) 2009-09-30

Family

ID=23576066

Family Applications (1)

Application Number Title Priority Date Filing Date
FI973559A FI120357B (fi) 1995-03-01 1997-08-29 Menetelmiä ja koostumuksia heterologisten polypeptidien erittämiseksi

Country Status (18)

Country Link
US (1) US5840523A (fi)
EP (1) EP0815246B1 (fi)
JP (1) JP3375970B2 (fi)
CN (1) CN1154736C (fi)
AT (1) ATE358181T1 (fi)
AU (1) AU701476B2 (fi)
BR (1) BR9607464B1 (fi)
CA (1) CA2213813C (fi)
DE (1) DE69636996T2 (fi)
DK (1) DK0815246T3 (fi)
ES (1) ES2285711T3 (fi)
FI (1) FI120357B (fi)
IL (1) IL117314A0 (fi)
NO (1) NO324920B1 (fi)
NZ (1) NZ303619A (fi)
RU (1) RU2208639C2 (fi)
WO (1) WO1996027016A1 (fi)
ZA (1) ZA961688B (fi)

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* Cited by examiner, † Cited by third party
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BR9607464B1 (pt) 2009-01-13
NO973985D0 (no) 1997-08-29
IL117314A0 (en) 1996-06-18
NO324920B1 (no) 2008-01-07
CA2213813A1 (en) 1996-09-06
DK0815246T3 (da) 2007-08-06
JPH10507368A (ja) 1998-07-21
EP0815246A1 (en) 1998-01-07
FI120357B (fi) 2009-09-30
JP3375970B2 (ja) 2003-02-10
ZA961688B (en) 1997-09-01
CN1154736C (zh) 2004-06-23
AU4998496A (en) 1996-09-18
DE69636996D1 (de) 2007-05-10
BR9607464A (pt) 1997-12-23
RU2208639C2 (ru) 2003-07-20
WO1996027016A1 (en) 1996-09-06
ATE358181T1 (de) 2007-04-15
DE69636996T2 (de) 2007-12-06
NO973985L (no) 1997-10-29
AU701476B2 (en) 1999-01-28
NZ303619A (en) 2000-02-28
CN1180379A (zh) 1998-04-29
ES2285711T3 (es) 2007-11-16
CA2213813C (en) 2008-05-27
MX9706607A (es) 1997-11-29
EP0815246B1 (en) 2007-03-28
FI973559A0 (fi) 1997-08-29
US5840523A (en) 1998-11-24

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