BR112022024996A2 - Anticorpos, ácido nucleico, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, agente terapêutico, uso do anticorpo e método para tratar um indivíduo com hepatite b - Google Patents

Anticorpos, ácido nucleico, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, agente terapêutico, uso do anticorpo e método para tratar um indivíduo com hepatite b

Info

Publication number
BR112022024996A2
BR112022024996A2 BR112022024996A BR112022024996A BR112022024996A2 BR 112022024996 A2 BR112022024996 A2 BR 112022024996A2 BR 112022024996 A BR112022024996 A BR 112022024996A BR 112022024996 A BR112022024996 A BR 112022024996A BR 112022024996 A2 BR112022024996 A2 BR 112022024996A2
Authority
BR
Brazil
Prior art keywords
antibody
antibodies
hepatitis
treating
producing
Prior art date
Application number
BR112022024996A
Other languages
English (en)
Inventor
Bourgine Maryline
Beretta Maxime
Mouquet Hugo
Hehle Verena
Pol Stanislas
Strick-Marchand Hélène
Ait-Goughoulte Malika
Peletier Nadège
Fischer Jens
Schlothauer Tilman
Van Puijenbroek Erwin
Driessen Wouter
Georges Guy
Original Assignee
Hoffmann La Roche
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche, Pasteur Institut filed Critical Hoffmann La Roche
Publication of BR112022024996A2 publication Critical patent/BR112022024996A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/082—Hepadnaviridae, e.g. hepatitis B virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

ANTICORPOS, ÁCIDO NUCLEICO, CÉLULA HOSPEDEIRA, MÉTODO PARA PRODUZIR UM ANTICORPO, COMPOSIÇÃO FARMACÊUTICA, AGENTE TERAPÊUTICO, USO DO ANTICORPO E MÉTODO PARA TRATAR UM INDIVÍDUO COM HEPATITE B. A invenção fornece anticorpos anti-S-HBs e métodos de uso dos mesmos.
BR112022024996A 2020-06-08 2021-06-08 Anticorpos, ácido nucleico, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, agente terapêutico, uso do anticorpo e método para tratar um indivíduo com hepatite b BR112022024996A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20305612 2020-06-08
PCT/EP2021/065260 WO2021249990A2 (en) 2020-06-08 2021-06-08 Anti-hbv antibodies and methods of use

Publications (1)

Publication Number Publication Date
BR112022024996A2 true BR112022024996A2 (pt) 2022-12-27

Family

ID=71614786

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022024996A BR112022024996A2 (pt) 2020-06-08 2021-06-08 Anticorpos, ácido nucleico, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, agente terapêutico, uso do anticorpo e método para tratar um indivíduo com hepatite b

Country Status (17)

Country Link
US (1) US20230340081A1 (pt)
EP (1) EP4161644A2 (pt)
JP (1) JP2023527918A (pt)
KR (1) KR20230020975A (pt)
CN (1) CN115697489A (pt)
AR (1) AR122569A1 (pt)
AU (1) AU2021288916A1 (pt)
BR (1) BR112022024996A2 (pt)
CA (1) CA3184495A1 (pt)
CL (1) CL2022003288A1 (pt)
CO (1) CO2022019225A2 (pt)
CR (1) CR20220659A (pt)
IL (1) IL298302A (pt)
MX (1) MX2022015206A (pt)
PE (1) PE20240080A1 (pt)
TW (1) TW202204396A (pt)
WO (1) WO2021249990A2 (pt)

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Also Published As

Publication number Publication date
US20230340081A1 (en) 2023-10-26
CL2022003288A1 (es) 2023-05-12
IL298302A (en) 2023-01-01
CA3184495A1 (en) 2021-12-16
PE20240080A1 (es) 2024-01-16
CN115697489A (zh) 2023-02-03
WO2021249990A2 (en) 2021-12-16
AU2021288916A1 (en) 2022-11-24
TW202204396A (zh) 2022-02-01
EP4161644A2 (en) 2023-04-12
AR122569A1 (es) 2022-09-21
CO2022019225A2 (es) 2023-03-17
KR20230020975A (ko) 2023-02-13
JP2023527918A (ja) 2023-06-30
WO2021249990A3 (en) 2022-02-10
CR20220659A (es) 2023-08-21
MX2022015206A (es) 2023-01-05

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